NEW YORK, Nov. 7, 2025 /PRNewswire/ — The New York Stock Exchange (NYSE) provides a daily pre-market update directly from the NYSE Trading Floor. Access today’s NYSE Pre-market update for market insights before trading begins. 

Kristen Scholer delivers the pre-market update on November 7th

• Equities are lower Friday morning after the major indices retreated Thursday in a volatile session. The S&P 500 shed 1.1% as signs of a cooling jobs market pushed down tech stocks and cryptocurrency.
• Traders scooped up bonds amid bets that the Federal Reserve will cut interest rates due to a softening labor market. The Central Bank has one final meeting scheduled this year in Mid-December.
• NYSE IPO’s Evommune and Grupo Aeromexico popped on their first day of trading yesterday. Evommune rallied 26% in its debut while Aeromexico rose 7.1%.

Opening Bell
PENCIL celebrates its 30^th anniversary

Closing Bell
World Leaders in Data and AI (WLDA) celebrates the 2025 WLDA Summit

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GUIYANG, China, Nov. 7, 2025 /PRNewswire/ — The International Conference of Mountain Tourism and Outdoor Sports (MTOS) 2025 is scheduled to open on November 11 in Guiyang City, Guizhou Province, China. With the continued theme “Integration of Culture, Tourism and Sports Presents a High-Quality Life,” the Conference will feature a series of events including the International Mountain Tourism Alliance (IMTA) Annual Conference, the International Mountain Tourism Promotion Conference, a Field Trip to Guizhou Mountain Tourism Destinations, and the Bank of Guizhou – Mountain Culture, Tourism and Outdoor Sport Equipment Exhibition.

The Conference is hosted by IMTA and supported by the Department of Culture and Tourism of Guizhou Province, Sport Administration of Guizhou Province, the Foreign Affairs Office of Guizhou Province, the Guiyang Municipal People’s Government, the Guizhou Tourism Industry Development Group Co., Ltd., and the Guizhou International Cultural Science and Technological Exchange Center. Bank of Guizhou serves as the sponsor of the Conference.

As one of the main events, the IMTA Annual Conference 2025 is a key exchange and cooperation platform for mountain tourism sector. During the Conference, the “IMTA 2025 Work Summary and 2026 Priorities” will be presented, the special publication of Innovation in Mountain Tourism and Community Co-development will be released, and designations for the second group of “World Famous Tourism Mountains” and “International Mountain Hiking Tourism Demonstration Routes” will be announced. In addition, certificates will be issued to new IMTA members.

The International Mountain Tourism Promotion Conference 2025, themed “Promote Mountain Prosperity and Create Shared Brilliance,” will bring together representatives from tourism authorities of various countries, embassies and consulates in China, mountain tourism destination management organizations, and tourism-related enterprises. Insights on mountain tourism destination development will be shared, experiences in building “World-class Mountain Tourism Destinations” will be exchanged, and achievements in sustainable mountain tourism will be showcased. The Research Report on Strategies for Developing Guizhou’s Inbound Tourism Market Targeting Key Countries in the Asia-Pacific Region will also be released during the session.

Titled exclusively by Bank of Guizhou, the “Bank of Guizhou – Mountain Culture, Tourism and Outdoor Sport Equipment Exhibition” will present photographic works themed “Life Amid the Earth’s Folds”, along with distinctive cultural tourism products and innovative outdoor sports equipment. The Exhibition is intended to to highlight the diverse appeal of mountain tourism, embody the concept of “High-quality Life,” and enhance the multidimensional experience for attendees.

ABU DHABI, UAE, Nov. 7, 2025 /PRNewswire/ — In the presence of His Highness Sheikh Theyab bin Mohamed bin Zayed Al Nahyan, Deputy Chairman of the Presidential Court for Development and Fallen Heroes’ Affairs, and His Excellency Dr. Thani bin Ahmed Al Zeyoudi, Minister of Foreign Trade, Silal, Abu Dhabi’s leading agri-food and technology company, signed a landmark joint venture (JV) agreement with Shouguang Colorful Manor Modern Agriculture Co., Ltd (SVG), one of China’s leading agricultural technology companies, during the China International Import Expo (CIIE) 2025.

Theyab bin Mohamed bin Zayed Witnesses JV Agreement Signing between Silal and SVG at China International Import Expo 2025

The agreement marks a major milestone in advancing UAE–China collaboration in sustainable agriculture, reinforcing the UAE’s vision to strengthen food security, diversify local production, and accelerate the adoption of advanced agri-tech solutions for harsh climates.

H.E. Dr. Thani bin Ahmed Al Zeyoudi, Minister of State for Foreign Trade, said: “The UAE continues to build strategic partnerships that strengthen our national food security ecosystem while deepening economic ties with key global partners like China. This joint venture reflects our shared commitment to innovation, sustainability, and responsible growth that benefits both nations and contributes to global food system resilience.”

Under the agreement, Silal and SVG will establish the region’s first facility for agricultural biological insects and jointly develop next-generation greenhouse infrastructure to serve the UAE and broader GCC markets. The partnership combines Silal’s deep market insight and farmer network with SVG’s technological expertise in AI-driven greenhouse systems, biological pollination, and precision farming. Reinforcing their shared vision for global market expansion, both parties have also established a long-term strategic partnership in fruit and vegetable trading, anticipating more than 1,000 containers of selected products from China to the UAE and surrounding markets annually.

H.E. Dhafer Al Qasimi, Group CEO of Silal, added: “This partnership represents a major step forward in Silal’s mission to advance sustainable agriculture through science and innovation. By combining SVG’s technological expertise with Silal’s deep understanding of the UAE’s agricultural landscape, this joint venture will enable long-term resilience, efficiency, and competitiveness across the agri-food value chain. Beyond innovation, our goal is to empower local farmers with access to cost-effective agricultural inputs and the latest technologies, helping them increase productivity, reduce costs, and enhance resource efficiency in a rapidly evolving environment.”

This collaboration will localize key agricultural inputs, reduce import dependency, and enable climate-smart, resource-efficient farming across the region. By integrating SVG’s advanced manufacturing capabilities with Silal’s operational leadership, the partnership will deliver scalable, cost-efficient solutions that enhance water efficiency, improve yields, and strengthen the UAE’s position as a regional hub for sustainable agriculture and innovation.

Mr. Ming Yang, Founder of Shouguang Colorful Manor Modern Agriculture Co., Ltd (SVG), said: “Our partnership with Silal presents an unparalleled opportunity to further enhance our advanced technologies and farming expertise under the region’s unique climate conditions. Together, we will combine our strengths to make a significant contribution to building a sustainable, innovative, and resilient food security ecosystem in the UAE.”

As part of the joint venture, USD 38 million will be invested to build an AI- and robotics-powered vegetable production hub in Al Foah, Al Ain, on a 9.8-hectare plot. The facility will serve as a regional innovation hub showcasing modern greenhouse technologies, water-efficient systems, and climate-smart agricultural models adaptable to Gulf environments.

The agreement follows the signing of two major MoUs between Silal and SVG, and represents a deepening of technical and commercial collaboration. It will enable knowledge transfer, capacity building, and technology localization, empowering UAE farmers with solutions that reduce import dependence, enhance yield, and promote environmental stewardship.

Theyab bin Mohamed bin Zayed Witnesses JV Agreement Signing between Silal and SVG at China International Import Expo 2025

Theyab bin Mohamed bin Zayed Witnesses JV Agreement Signing between Silal and SVG at China International Import Expo 2025

• Findings provide scientific insights into the contribution of small interfering RNA (siRNA) and therapeutic vaccination towards the HBV functional cure strategy

DURHAM, N.C. and BEIJING, Nov. 7, 2025 /PRNewswire/ — Brii Biosciences Limited (“Brii Bio,” or the “Company,” stock code: 2137.HK), a biotechnology company developing therapies to improve patient health across diseases with high unmet medical need, today announced the publication of results from its Phase 2 ENSURE study in the peer-reviewed journal Nature Medicine. The study evaluates the efficacy and safety of an siRNA, elebsiran, in combination with pegylated interferon alfa (PEG-IFNα), compared to PEG-IFNα monotherapy. Furthermore, this study evaluates the potential role of an HBV therapeutic vaccine, BRII-179, in identifying immunologically responsive patients and improving hepatitis B surface antigen (HBsAg) loss rates.

The article, titled “Elebsiran and PEG-IFNα for chronic hepatitis B infection: a partially randomized, open-label, phase 2 trial“, is now available online [link].

The ENSURE study was conducted in two parts in virally suppressed chronic HBV patients. In Part I (Cohorts 1-3), participants naïve to BRII-179 were randomized to receive 48 weeks of PEG-IFNα alone or in combination with elebsiran (200 mg or 100 mg administered every 4 weeks [Q4W]). In Part II (Cohort 4), participants previously treated with 9 doses of elebsiran and BRII-179 in a completed Phase 2 study (BRII-179-835-001) were categorized as BRII-179 anti-HBs responders or non-responders based on peak hepatitis B surface antibody (anti-HBs) levels (≥10 IU/L or <10 IU/L, respectively), and subsequently received 48 weeks of elebsiran (100 mg Q4W) plus weekly PEG-IFNα in the ENSURE study.

Key results from this publication include:

• Cohorts 1-3: At 24 weeks post-EOT, HBsAg loss was observed in 4 of 19 participants (21.1%) in Cohort 2 (elebsiran 200 mg + PEG-IFNα) and 6 of 18 participants (33.3%) in Cohort 3 (elebsiran 100 mg + PEG-IFNα), compared to 1 of 18 participant (5.6%) in Cohort 1 (PEG-IFNα monotherapy).
• Cohort 4: At 24 weeks post-EOT, HBsAg loss was observed in 9 of 31 participants (29.0%), with a notably higher response among BRII-179 anti-HBs responders (8/19, 42.1%) compared to non-responders (1/12, 8.3%). BRII-179 anti-HBs responders also achieved more rapid HBsAg reductions and HBsAg seroclearance compared to non-responders.
• Elebsiran and PEG-IFNα combination therapy was generally safe and well tolerated across all cohorts.

The randomized, active-controlled design of Cohorts 1-3 was a gold standard in validating the clinical benefit of elebsiran over PEG-IFNα monotherapy, providing an important benchmark for future development of siRNA towards HBV functional cure.

The novel design of Cohort 4 explored a patient response-guided treatment approach for more personalized decision-making, maximizing response rates in those most likely to benefit while avoiding unnecessary and lengthy treatments in others.

Other important observations are 1) participants previously treated with BRII-179 and elebsiran experienced faster decline and loss of HBsAg, suggesting that BRII-179 may prime the immune system for improved responsiveness to subsequent curative therapy; 2) 50% (4/8) of anti-HBs responders who achieved sustained HBsAg loss had baseline HBsAg levels exceeding 1,500 IU/mL when enrolled in the previous BRII-179-835-001 study, suggesting that BRII-179 may elicit anti-HBs responses in patients with high baseline HBsAg levels. With its favorable safety profile, BRII-179 could play a unique role in priming and enriching patients regardless of the baseline HBsAg levels, expanding the population eligible for future curative regimens.

“The ENSURE study was designed to provide much-needed clarity and to answer critical scientific questions about curative treatment for chronic hepatitis B,” said Professor Jidong Jia, lead principal investigator of the ENSURE study, “It is encouraging to see that the 24-week follow-up data remain consistent with the EOT results, substantiating the added clinical benefit of elebsiran and pointing to the potential new roles of BRII-179 in priming and enriching CHB patients for achieving higher cure rates. We look forward to validating these findings in confirmatory studies.”

About Hepatitis B

Hepatitis B virus (HBV) infection is one of the world’s most significant infectious disease threats with more than 254 million people infected globally.^[1] Chronic HBV infection is the leading cause of liver disease and an estimated 820,000 people die of complications from chronic HBV infection each year.^[1] HBV is of exceptional concern in China, where 87 million people are chronically infected.^[2]

About BRII-179

BRII-179 is a novel recombinant protein-based HBV immunotherapeutic candidate that expresses the Pre-S1, Pre-S2, and S HBV surface antigens, and is designed to induce enhanced and broad B-cell and T-cell immunity. In November 2023, the Center for Drug Evaluation (the “CDE”) of the National Medical Products Administration (the “NMPA”) granted BRII-179 Breakthrough Therapy Designation.

About Elebsiran

Elebsiran is an investigational subcutaneously administered HBV-targeting siRNA designed to degrade hepatitis B virus RNA transcripts and limit the production of hepatitis B surface antigen. It has the potential to have direct antiviral activity against HBV and HDV. It is the first siRNA in the clinic to include Enhanced Stabilization Chemistry Plus technology to enhance stability and minimize off-target activity, which potentially can result in an increased therapeutic index. Brii Bio licensed exclusive rights to develop and commercialize elebsiran for the Greater China territory from Vir Biotechnology, Inc. in 2020. In May 2024, the CDE of the NMPA granted elebsiran Breakthrough Therapy Designation.

About Brii Bio

Brii Biosciences Limited (“Brii Bio“, stock code: 2137.HK) is a biotechnology company developing therapies to address major public health challenges where patients experience high unmet medical needs, limited choice and significant social stigmas. With a focus on infectious diseases, the Company is advancing a broad pipeline of unique therapeutic candidates with lead programs against hepatitis B virus (HBV) infection. The Company is led by a visionary and experienced leadership team and has operations in key biotech hubs, including Raleigh-Durham, the San Francisco Bay Area, Beijing and Shanghai. For more information, visit www.briibio.com.

– Tickets and travel packages now available for global K-pop fans 

– “Play&Stay” package combines live performances with premium Korean travel experiences

SEOUL, South Korea, Nov. 7, 2025 /PRNewswire/ — interpark Global, a travel and ticketing platform operated by NOL Universe for international visitors, is inviting global fans to Korea this holiday season with exclusive access to two of the year’s most anticipated K-pop events — G-DRAGON’s encore concert and the SBS Gayo Daejeon. The platform will offer both ticket-only options and combined travel packages, introducing a new way for fans to experience K-culture through live performances and immersive travel. 

G-DRAGON’s “2025 WORLD TOUR [Übermensch] IN SEOUL: ENCORE” will take place from December 12 (Fri) to 14 (Sun) at Gocheok Sky Dome in Seoul. interpark Global will open ticket sales for international fans, providing both standard tickets and “Play&Stay” packages that include hotel accommodations. These packages allow visitors to enjoy a seamless premium experience combining live K-pop performances with Korean travel. Fan club pre-sales begin on November 10 (Mon) at 9 PM KST / 7 AM ET, followed by general sales on November 11 (Tue) at 8 PM KST / 6 AM ET.

interpark Global will also serve as a major partner for the “2025 SBS GAYO DAEJEON Winter,” taking place on December 25 (Thu) at Inspire Arena in Incheon. Featuring a star-studded first lineup including Stray Kids, TOMORROW X TOGETHER, ENHYPEN, IVE, and LE SSERAFIM, this year’s event — themed “Golden Loop” — will mark the grand finale of the 2025 K-pop season. interpark Global will offer exclusive “Play&Stay” packages that combine the special pre-show “Blue Carpet” session with shuttle service and hotel accommodations, providing fans with a unique on-site experience. K-culture travel packages are scheduled to go on sale in mid-November, and interpark Global members can also receive a ₩30,000 discount coupon for shuttle packages purchased through the end of November.

An interpark Global representative said, “This holiday season, we look forward to welcoming global fans to experience K-pop up close through interpark Global. We will continue expanding our services to help fans from around the world experience the vibrant energy of Korean culture firsthand through innovative travel-linked concert experiences.”

interpark Global serves over 7.6 million international users, offering ticketing for K-pop concerts, festivals, musicals, and other cultural events. The platform’s signature Play&Stay program bundles accommodations and transportation with live performance access, creating an integrated cultural tourism experience that strengthens Korea’s position as a global hub for entertainment. 

EL MONTE, Calif., Nov. 7, 2025 /PRNewswire/ — NAVEE, a fast-growing leader in electric mobility, today announced the launch of its all-new G5 Series Electric Scooter, featuring the G5, G5 Pro, and G5 Max, designed to deliver a more connected, more stable, and more inspiring commuting experience.

The G5 Series Electric Scooter showcases a futuristic diamond-cut frame paired with intelligent control systems and advanced suspension technology, combining modern aesthetics with precision engineering. Prices start at $549.99 for G5, $599.99 for G5 Pro, and $699.99 for G5 Max. The Max model is now available on NAVEE’s official online store, while other models will be gradually launched on the store and Amazon.

“With the G5 Series, we set out to redefine urban riding,” said Loong, Product Manager at NAVEE. “Every detail was designed to make riding smarter, safer, and more enjoyable.”

The G5 Series features NAVEE’s Advanced Traction Control System (TCS) for enhanced grip on wet or uneven surfaces, combined with dual suspension and 10-inch tubeless tires for a smooth and confident ride. The dual-braking system and IPX5 water resistance further ensure safety in all conditions.

Built with automotive-grade QSTE 420 high-strength steel, each scooter has passed static load tests supporting over 2,205 lbs (1,000 kg), demonstrating exceptional structural integrity and long-term durability.

In terms of range reliability, all G5 models were tested at 77°F(25°C) with a 165 lbs(75 kg) rider, traveling at an average speed of 9 mph(15 km/h) on flat pavement. Under these conditions, the G5 Max achieves up to 44 miles of range, offering dependable performance for daily commutes and longer weekend rides alike.

The G5 Max also brings a new level of intelligence to electric mobility with features such as Bluetooth proximity unlock, Apple Find My integration, and smart energy recovery, allowing riders to enjoy both performance and peace of mind on every journey.

Looking ahead, NAVEE plans to expand its intelligent ecosystem with more connected mobility solutions, integrating data, sustainability, and rider experience to shape the future of green transportation.

About NAVEE

NAVEE is a leading brand in electric mobility, recognized for its industry-leading suspension technology, and as the fastest-growing new brand in sales, delivering products with cutting-edge design and sustainability. Discover how NAVEE is shaping the next generation of smart urban mobility at https://naveetech.us/.

Japan’s newly appointed Foreign Minister Toshimitsu Motegi sparked an unexpected viral moment at APEC 2025 after stopping by Imunika — the official coffee sponsor of APEC 2025 Korea, a Korea–U.S. startup redefining “Wellness Specialty Coffee.”

SEOUL, South Korea and WASHINGTON, Nov. 7, 2025 /PRNewswire/ — A quiet exchange at the APEC 2025 Korea Summit became one of the event’s most unexpected stories. Toshimitsu Motegi, Japan’s newly appointed Foreign Minister — soon to help steer Japan–U.S. tariff negotiations — was filmed sampling Imunika, a small bio-fermented coffee startup that unexpectedly found global attention.

The clip, posted to Motegi’s official social-media account, drew over 4 million views, 60,000 shares, and 15,000 comments within 48 hours, softening his characteristically firm public image. In a follow-up interview, Motegi said, “I didn’t expect the video introducing the coffee to be viewed more than four million times.”

Founded in Korea and the US, Imunika created a disruptive innovation in coffee, representing a new wave of Wellness Specialty Coffee that blends Korea’s fermentation technique with Seattle’s specialty roasting profile. Through its patented bio-fermentation process, medicinal mushrooms are integrated with coffee beans, producing a smoother, lower-caffeine cup that supports immune health, gut balance, and mental clarity — what the company calls “Mushroom Coffee 2.0.”

“It was a completely serendipitous moment for us,” said Jinhu Park, Imunika’s Founder and CEO. “Imunika represents Korea’s wellness culture — each cup is meant as an investment in oneself, not a mere act of consumption. At APEC, it was humbling to see how naturally that idea resonated among the world’s leaders.”

The company’s story is rooted in a personal journey. Park, a Cornell-educated entrepreneur, began developing Imunika’s mushroom fermentation technique with his family after losing his younger brother to cancer in 2020 — turning that tragic experience into a mission to redefine the world’s most beloved beverage, coffee.

What began as a search for healing became a cup now connecting Korea, Japan, and the United States — proof that shared taste can sometimes achieve what diplomacy aims for.

About Imunika
Imunika is a premium wellness brand rooted in Korea’s fermentation heritage. Through a patented four-week bio-fermentation process and a proprietary seven-mushroom complex, Imunika crafts low-caffeine, immune-supporting whole-bean coffee made for decision makers and intention seekers

Website: www.imunika.com
Instagram: @imunika