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YEAHKA Accelerates Overseas Growth in Q3, with its Invested Company Fushi Empowering Jumbo with One-Stop CRM Solution

HONG KONG, Nov. 27, 2025 /PRNewswire/ — On November 24, 2025, YEAHKA Limited (Stock Code: 9923.HK), a leading commerce enablement technology platform, issued a voluntary announcement. The report indicated that the Company’s overseas business maintained robust growth in the third quarter, with its one-stop payment and value-added services continuing to expand its base of branded clients. During the quarter, through its invested company Fushi Technology, YEAHKA served well-known chain brands such as PlayMade, Jumbo, and Shihlin Taiwan Street Snacks. Notably, the overseas Gross Payment Volume (GPV) for the third quarter in 2025 reached nearly RMB 1.3 billion, surpassing the total overseas GPV for the full year of 2024.

It is reported that the membership management product developed for Jumbo by Fushi Technology, a company invested in by YEAHKA, has recently been officially launched. Jumbo is a renowned chain seafood brand founded in Singapore in 1987, famous among customers for its signature Singapore-style Chilli Crab and Black Pepper Crab. The brand has now expanded its presence to countries including China, Vietnam, and Thailand.

This membership management product is built upon Fushi’s self-developed, all-in-one intelligent customer loyalty and marketing automation platform. It is designed to enhance Jumbo’s capability in managing customer assets, further improve customer retention rates, and create a seamless dining experience for their users.

Through Fushi’s CRM solution, Jumbo can achieve deep integration across its multiple restaurant outlets, allowing diners to accumulate points and redeem rewards across venues. By incorporating multiple service features and reward mechanisms such as integrated loyalty points, e-vouchers, and mobile ordering, the solution helps Jumbo optimize the entire consumer journey from reservation to payment.

According to public data, the Southeast Asian region, with a population of over 600 million and high penetration of mobile payments, offers broad prospects for the F&B and retail markets. However, local merchants commonly face challenges such as high customer acquisition costs, low conversion rates, and difficulty in measuring marketing ROI. Recognizing this market gap, Fushi precisely addresses it by providing digital tools that empower merchants to shift their operational focus from “traffic acquisition” to “existing customer value maximization.” This enables refined operation and value enhancement of customer assets, helping merchants gain a competitive edge and overcome growth bottlenecks in the rapidly evolving market.

The successful deployment of this collaborative product not only signifies important market recognition for Fushi’s CRM solution, but also demonstrates the vast potential for the global expansion of YEAHKA’s one-stop payment and value-added service business, driven by its unique strengths of vertical expertise, rich consumer behavior data, and strong capacity for innovation.

 

Minesto AB: Interim Management Statement 1 January – 30 September 2025

GOTHENBURG, Sweden and VÄSTRA GÖTALAND, Sweden, Nov. 27, 2025 /PRNewswire/ — CEO Dr Martin Edlund:”Minesto moves forward with a funded and reinforced action plan for commercial breakthrough.”

Significant events July-September 2025

In July Minesto announced a reorganization over the last year was completed, resulting in readiness to deliver commercial projects and reduced fixed costs. Reshaping of the organization include relocation geographically, management team set-up and product development focus. The completed reorganization resulted in a reduction of fixed costs by approximately 35%.

In August the company appointed new CFO, Alexander Jancke, strengthening the business development agenda with start October 2025. Former CFO Gustav Kvibling leaves his position to pursue opportunities outside the company.

Together with project partners Sev, Capture Energy and IVL, Minesto completed a planning and project set-up workshop for the 25 MSEK Microgrid Project awarded by Swedish Energy Agency. In parallel with the project, Minesto has added an integration of two local end-user applications of tidal energy in the Faroe Islands to strengthen customer involvement.

On 16 September 2025, Minesto announced that the Board of Directors, conditional on the subsequent approval of an extraordinary general meeting, had resolved on a rights issue of shares of approximately SEK 152.4 million. The subscription price was determined to SEK 1.85 per share. Minesto received guarantee commitments subject to customary conditions which, in aggregate, amount to SEK 99.0 million, corresponding to approximately 65.0 percent of the Rights Issue.

After the end of the period

On 28 October, Minesto announced the outcome of the company’s rights issue of up to 82,364,595 shares. 33,436,356 shares, corresponding to approximately 40.6 percent of the Rights Issue, had been subscribed for with the support of subscription rights. Additionally, applications for subscription of 575,828 shares, corresponding to approximately 0.7 percent of the Rights Issue, had been received for subscription of shares without the support of subscription rights. In aggregate, the subscriptions with the support of subscription rights and the applications for subscription without the support of subscription rights correspond to approximately 41.3 percent of the Rights Issue. Hence, guarantee commitments of 19,501,329 shares, corresponding to approximately 23.7 percent of the Rights Issue, will be utilized. The Rights Issue provides the company with proceeds of approximately SEK 99.0 million before deduction of costs related to the Rights Issue.

On 30 October, Git Sturesjö Adolfsson resigned as a member of the Company’s Board. Deputy Board Member Andreas Gunnarsson assumed her position.

The Board of Directors resolved to allow Fenja Capital to set off its outstanding loan claims, including accrued interest, totalling approximately SEK 22.2 million as payment for part of the shares that Fenja Capital has been allocated and subscribed for in the Rights Issue.

On 8 October, Minesto invited investors and the public with an interest in technology and energy systems to a unique opportunity to experience firsthand the tidal energy kite Dragon 4 “Íðunn” as she was brought home for a break from production duty at the company’s demonstration site in the North Atlantic where it produces electricity to the Faroe Islands grid. The event attracted around 150 guests, presentations are available on the company’s youtube channel.

In October, Minesto was part of a high-level Swedish delegation to South Korea aiming to explore new partnerships and strengthen bilateral collaboration in the green transition. The delegation was led by HRH Crown Princess of Sweden and supported by Swedish minister for Foreign Affairs and Swedish minister for Infrastructure and Housing. The delegation was part of Focus Asia – Sweden’s strategy for trade and investment in the region. Extensive tidal and ocean current resources make South Korea a highly attractive market for Minesto.

In November, Minesto participated in high-level Swedish business delegation to Canada in connection with the royal couple’s state visit. The delegation, led by the Swedish Minister for Energy and Business and Minister for Defence, aimed to strengthen Swedish-Canadian relations and promote innovation with focus on AI, defence & security and electrification. Significant ocean resources with tidal streams and political support for ocean energy make Canada a highly attractive market for Minesto.

Minesto was selected to be part of InnoEnergy’s annual industry event The Business Booster, this year in Lisbon in October. InnoEnergy, initiated by the European Institute of Innovation and Technology (EIT), is Europe’s investment company at the forefront of clean energy transition and Minesto was invited as one of the industrial scale-ups driving Europe’s energy transition.

During the third quarter, Minesto continued to attract credible media publicity – the tidal energy kites were featured in Forbes online as well as in a new in-depth TV documentary, airing on Arte and available in German and French.

The Group in summary 1 January–30 September 2025

  • Total operating income for the period amounted to SEK 17,046 thousand (19,320) and mainly consist of capitalised development work. Net sales amounted to SEK 0 thousand (75).
  • Operating loss for the period amounted to SEK –28,158 thousand (–32,884). The negative result is largely attributable to business development and administration related to technology development. During the period personnel costs of SEK 17,045 thousand (19,222) has been capitalised as development work.
  • At the end of the period, the intangible fixed assets amounted to SEK 567,805 thousand (531,569), of which capitalised development costs SEK 549,991 thousand (514,633) and capitalised patent expenses SEK 17,814 thousand (16,937).
  • During the period, payments of SEK 4,416 thousand (27,803) were received from public funding schemes, of which SEK 54 thousand (26,474) is approved claims and the remaining part is advance payments. Grants of SEK 1,263 thousand (716) were accounted for during the period, of which SEK 1,263 thousand (716) has reduced the acquisition value of the capitalised development costs.
  • Cash flow for the period amounted to SEK –8,182 thousand (39,418). At the end of the period, cash and cash equivalents amounted to SEK 26,422 thousand (54,790).
  • At the end of the period, equity amounted to SEK 554,230 thousand (571,836) divided into 205,911,488 shares (194,116,040), of which loss for the period amounted to SEK –30,138 thousand (–32,731).

The Interim Management Statement t is available to download at Minesto’s website:
www.minesto.com/investor/investor-information

CEO comment:

Minesto moves forward with a funded and reinforced action plan for commercial breakthrough

This Third quarter and beyond have been a busy period for Minesto. First and foremost, we have secured funding by a rights issue to keep pushing our commercial agenda forward. This was achieved in a tough capital market with proceeds of SEK 99 million before deduction of transaction fees and loan payback. The size of this investment is satisfactory and immediately creates momentum in reinforcing our action plan for commercial breakthrough. However, the overall message from the capital market to Minesto is clear: the commercial roll-out needs to accelerate.

Let me give you a brief run-through on how we execute our plan to deliver business based on our groundbreaking innovation.

A unique sales team

The volume of sales offers is on the rise, as well as the number of markets where step-in offers are made. It is no secret that most actors in a novel market are “late movers” so the increasing volume in market activities and sales offers is key to push customers into faster and larger commitments.

We have expanded and organized a multidisciplinary commercial team with expertise in key areas necessary for promoting our power plants:

  • Site identification expertise (ocean flow simulations etc.)
  • Power plant design adaptation to maximize production yield
  • Design of tidal energy parks and associated business simulation
  • Construction of project investment cases
  • Energy system analysis for assessment of the value of adding tidal energy production

Our approach is process-oriented where re-use and improvement iterations of product descriptions, tender documentation, legal-frameworks and content of customer offers also supports an increased volume of sales activities, but even more so the quality of our work. Given the novel nature of our ocean energy sector and the uniqueness of our technology, we have been forced to and succeeded with putting together a truly unique sales team to deliver business.

Putting the Rights issue investment to work

The purpose of our recent investment round is to strengthen our commercial offer and contribute to risk reduction of investment offers for Dragon farms (tidal array projects). This marks a substantial shift in focus, built on the following core activities.

  • Since August, with substantial technical contributions from partners and funding from the Swedish Energy Agency of 25 MSEK, we are expanding the test site in Vestmanna into a complete microgrid-system for sales and delivery. With this system, we will be able to address non-grid connected needs in the Faroe Islands, but also to offer tidal microgrids in all suitable commercial contexts globally. We have end-customer involvement to make it into a complete microgrid business set-up where we will be paid for fossil fuel and CO2 emission reductions.
  • We are also adding substantial value to the project investment case at Hestfjord in the Faroe Islands via site development activities. We have progress in a range of areas to further reduce environmental risks (an example of this includes sound measurements), to make assessments of production yield more robust (with simulations of array design) and improvements of our maintenance set-up. This work is all done in close collaboration with SEV and other potential commercial partners. Our goal is clearly within reach, to secure that the world’s first commercial tidal array at scale will be a Minesto Dragon Farm.
  • We limit site development investments to the Hestfjord project, but all aspects of maturing that project has merits for other Dragon Farm opportunities, both existing and new. In this way, our ability to on-board project development partners and site project investments is significantly increasing. Our extended sales capability combined with the site-development achievements in Hestfjord makes it possible for us to revisit existing partnerships in markets such as Wales, Taiwan and the Philippines, but also to add new ones in a range of markets such as Canada, Ireland and Japan. Our go-to-market model is based on forming strategic partnerships with project developers in basically all relevant tidal markets. We have serious interest from potential partners across the globe and are organized to engage with all of them.

The value of tidal energy from our Dragons

Minesto continues to lead the industry in terms of LCOE, with a 2,5 M EUR/MW in CAPEX, thanks to our outstanding power-to-weight-ratio and efficient energy conversion. With the first 30 M EUR investment for the first tidal energy farm (10 MW), we foresee an LCOE at 150 EUR/MWh – outperforming other ocean renewables. Notably, this is the world-first installation and standard cost-reductions from learning and increased scale will enable large scale (multimegawatt) commercial build out at competitive cost-levels.

As an extension to our business development work on analyzing our cost-competitiveness, we now also assess how our tidal electricity production contributes to the total cost of electricity to serve consumers in a given market. In-short, markets with a solid tidal resource can shape a cost-efficient roadmap towards net-zero if they rely on our Dragons. If not, the cost of storage, build of over-capacity and system losses makes it economically unfeasible to reach net-zero relying only on the so-called mature renewables, solar and wind. We conclude that for our target markets an energy system including our tidal technology will be able to cut cost-of-electricity in half compared to a renewable scenario without us. The message we send to potential customers and energy stakeholders is that it may be perceived as risky to “bet” on our novel renewable energy technology, but it is even more risky to stick to existing solutions that are proven insufficient to deliver an affordable energy transition towards sustainability.

Thus, our tidal energy offer has a key role to play with its base-load characteristics and competitive cost levels. We are, more than ever in the driver’s seat to be the true pioneers, delivering the large-scale commercial breakthrough for ocean renewable energy.

/Martin Edlund, CEO of Minesto

Contact
Cecilia Sernhage, Chief Communications Officer
+46 735 23 71 58
ir@minesto.com 

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https://news.cision.com/minesto-ab/r/interim-management-statement-1-january—30-september-2025,c4273429

The following files are available for download:

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Minesto AB_Interim Management Statement Q3_2025

https://mb.cision.com/Public/14621/4273429/8d391cf52a968824.pdf

PR 271125 Interim Management Statement 1 January 30 September 2025 Minesto AB

 

Lenovo Neptune Powers the World’s Greenest and Most Efficient HPC & AI Systems, Delivering up to 40% Lower Energy Use

  • Lenovo ranks #1 on the Top500 Supercomputers and Green500 lists
  • Neptune systems deliver up to 100% heat removal achieving 1.1 PUE
  • Warm-water cooling operates up to ~45 °C, eliminating chilled-water requirements

SYDNEY, Nov. 27, 2025 /PRNewswire/ — Lenovo today announced expansion of its Neptune liquid cooling technology across its data center portfolio, advancing sustainable infrastructure for the age of AI. Designed to address the rising compute and energy demands of modern data centers, Lenovo Neptune enables servers to operate with about 40% lower power than air-cooled systems, ensuring consistent performance while lowering environmental impact.

Lenovo continues to strengthen its leadership in energy-efficient computing. As of November 2025, Lenovo ranks #1 on both the Top500 and Green500 lists, powered significantly by Neptune-enabled supercomputers that deliver world-class performance with industry-leading sustainability.

A Cooling Approach for the AI Era

The IDC & Lenovo CIO Playbook 2025 highlights improving sustainability as a top business priority. As organizations accelerate AI adoption, data centers are facing unprecedented thermal and performance pressures due to soaring compute density and energy use. Traditional air cooling is no longer sufficient to manage the heat generated by modern AI systems.

Lenovo’s Neptune Direct Water-Cooling (DWC) technology addresses these challenges by circulating warm water directly to system nodes to remove heat from CPUs, GPUs, and memory. Unlike chilled-water systems that operate at around 18 °C, Neptune allows coolant temperatures up to ~45 °C, eliminating chiller requirements, reducing reliance on air-handling units, and ensuring a stable thermal envelope for AI and HPC workloads.

Built on more than a decade of innovation and hundreds of patents, the sixth-generation Neptune systems feature advanced water-based cooling architectures designed to support higher rack densities and enable efficient operations without specialized air conditioning. The new vertical liquid-cooling chassis delivers accelerated computing in a compact, 100% liquid-cooled system, eliminating the need for power-hungry fans and lowering energy use across the data center.

Advancing Lenovo’s Net-Zero Vision

Lenovo is progressing on its mission to achieve net-zero carbon emission by 2050 (validated by Science Based Targets initiative (SBTi)), advancing long-term emissions reduction through renewable energy adoption, efficient product design, and more sustainable data center operations. Neptune technology is integral to this journey, offering tangible reductions in data center power consumption and enabling customers to progress toward their sustainability goals without compromising on AI performance.

Meeting Global Demand for Sustainable Data Infrastructure

Driven by soaring demand for AI, cloud, and advanced digital services, data centers across Asia Pacific are expanding rapidly – and so is their need for power. Electricity consumption in the region is expected to rise from 320 terawatt-hours in 2024 to 780 terawatt-hours by 2030.

“Across Asia Pacific, organizations are looking for AI infrastructure that is not only powerful but also fundamentally more energy efficient. Neptune gives our customers that advantage. Our leadership on the Top500 and Green500 rankings demonstrates the real-world impact of these innovations. As AI scales, solutions that combine performance with responsible energy use will define the next era of digital growth, and that is exactly what Lenovo is delivering,” said Kumar Mitra, Executive Director, Lenovo Infrastructure Solutions Group (ISG), Central Asia Pacific and Australia & New Zealand.

Sustainable Performance at Scale

Lenovo continues to advance sustainable AI-ready infrastructure through its Neptune ecosystem, which integrates Direct-to-Node warm-water cooling, Rear Door Heat Exchangers, and Thermal Transfer Modules into a highly efficient, closed-loop design. Warm coolant flows through precision cold plates on key components, rising by about 10–15 °C before transferring heat through a separate facility loop for reuse, removing the need for chilled water while maintaining stable performance. Combined with Lenovo’s ThinkSystem and ThinkAgile servers, Neptune helps customers lower power consumption and TCO while supporting reliable, high-density AI and HPC workloads.

Lenovo’s ThinkSystem SR780a powered by Lenovo Neptune, shows how warm-water cooling delivers real efficiency benefits. The system has achieved a Power Usage Effectiveness (PUE) of 1.1, a milestone in data center efficiency. PUE indicates how much of power is used for computing versus cooling. A perfect score is 1.0. A PUE of 1.1 means 0.1 watts are spent on cooling, a level that is very difficult to achieve with air-cooled systems.

Lenovo is already driving measurable impact for some of the world’s most demanding workloads. For example, at DreamWorks Animation, Neptune-powered HPC systems delivered a 20% increase in performance while reducing cooling requirements. The technology is also trusted across Asia Pacific by leading meteorological agencies in Korea and Malaysia, as well as universities, research organizations, and digital content creators. Its broad adoption underscores Neptune’s ability to support diverse, high-density AI and HPC workloads efficiently and reliably.

The technology is already deployed in several of the world’s most energy-efficient supercomputers, reinforcing Lenovo’s position as a leader in responsible computing. Neptune is a key enabler of Lenovo’s broader goal of helping customers build AI-ready infrastructure that is both powerful and environmentally responsible.

About Lenovo

Lenovo is a US$69 billion revenue global technology powerhouse, ranked #196 in the Fortune Global 500, and serving millions of customers every day in 180 markets. Focused on a bold vision to deliver Smarter Technology for All, Lenovo has built on its success as the world’s largest PC company with a full-stack portfolio of AI-enabled, AI-ready, and AI-optimized devices (PCs, workstations, smartphones, tablets), infrastructure (server, storage, edge, high performance computing and software defined infrastructure), software, solutions, and services. Lenovo’s continued investment in world-changing innovation is building a more equitable, trustworthy, and smarter future for everyone, everywhere. Lenovo is listed on the Hong Kong stock exchange under Lenovo Group Limited (HKSE: 992) (ADR: LNVGY). To find out more visit https://www.lenovo.com, and read about the latest news via our StoryHub.

Media Contact:
LenovoISGIndia@zenogroup.com 

Hengan International Donates a Total of HKD6 Million in Cash and Daily Supplies to Support Post-fire Relief Efforts at Tai Po Wang Fuk Court


HONG KONG SAR – Media OutReach Newswire – 27 November 2025 – Hengan International Group Company Limited (“Hengan International” or the “Company”, SEHK stock code: 1044, together with its subsidiaries, the “Group”) announces a donation of total HK$6 million in cash and daily supplies to fully support post-disaster relief and resettlement efforts at Wang Fuk Court in Tai Po, helping affected residents overcome the challenges they face.

The donation comprises HK$3 million in cash and emergency daily supplies valued at HK$3 million, aimed at supporting the emergency relief and transitional needs of affected residents.

Hengan International extends its deepest condolences to the victims of fire at Tai Po Wang Fuk Court and pays the highest tribute to frontline rescue and relief personnels. The Group will continue to closely monitor the progress of relief efforts and provide ongoing support in full swing.

With unity and solidarity, Hengan International stands with the people of Hong Kong.

Blessings upon Hong Kong and the nation.Hashtag: #恒安國際

The issuer is solely responsible for the content of this announcement.

Hengan International Group Company Limited

Hengan Group was established in 1985. It is principally engaged in production, distribution and sales of personal hygiene products in mainland China. The shares of Hengan International have been listed on the Hong Kong Stock Exchange since 1998. The Group has been a Hang Seng Index constituent since June 2011 and a constituent of the Hang Seng Corporate Sustainability Benchmark Index (HSSUSB) since September 2024.

Philippines Ready to Take Helm of 2026 ASEAN Chairmanship

Association of Southeast Asian Nations (ASEAN). This photo is used for representational purposed only.

By Alina Khai and Laotian Times – Malaysia’s 2025 Association of Southeast Asian Nations (ASEAN) chairmanship delivered renewed momentum in economic integration and regional cooperation, but the bloc now faces defining strategic tests as leadership transitions to the Philippines next year.

After a year of high-stakes diplomacy, Malaysia helped drive progress on the ASEAN Digital Economy Framework Agreement (DEFA), launched the ASEAN Geo-Economics Task Force, introduced the ASEAN Community Vision 2045, and advanced efforts toward a long-term strategic roadmap. 

Vietnam’s deputy foreign minister Dong Hoang Giang said 2025 saw “strong breakthroughs in economic growth and innovation,” with new frameworks in digital cooperation, energy connectivity, and technology-led development.

A major achievement was the inaugural ASEAN-Gulf Cooperation Council (GCC)-China Summit, which analysts say deepened ASEAN’s role as a regional convener. Institute of Strategic and International Studies chairman Faiz Abdullah said China’s technological strength “complements the GCC’s substantial resources,” reinforcing ASEAN’s centrality in an increasingly contested Indo-Pacific.

US Ambassador Edward Kagan also highlighted Southeast Asia’s rising strategic significance, noting that key “chapters of the 21st century” will be written in the Indo-Pacific.

Zanariah Zainal Abidin, director general of the ASEAN-Malaysia National Secretariat, stressed that the region must remain inclusive. 

“The Indo-Pacific is not a battleground to be won,” she said. “ASEAN’s strength lies in dialogue, bridging divides, and keeping the region open and cooperative.”

Unfinished Business

Despite momentum, the bloc now faces pressure to deliver. 

Several new frameworks remain conceptual, with limited mechanisms for implementation. Senior fellow Joanne Lin of Institute of Southeast Asian Studies (ISEAS)-Yusof Ishak Institute argued that ASEAN must operationalize these initiatives through clear roadmaps, financing, and deeper private-sector engagement-especially as global tech competition intensifies.

Deputy investment minister Liew Chin Tong said ASEAN could become a “champion of middle technology” and a reliable semiconductor hub if member states maintain neutrality and trust.

Development gaps continue to widen following Timor-Leste’s entry as the 11th members of the association, with veteran diplomat Ilango Karuppannan warning that ASEAN risks splitting into “three tiers of wealth” without urgent corrective action.

Regional political sensitivities also remain. 

The Thai-Cambodian detente is still fragile, and ASEAN has yet to build a robust peacekeeping architecture. International Islamic University’s Phar Kim Beng emphasized renewed political will to activate existing mechanisms as consensus remains vital to the bloc’s identity.

The border clashes between two nations erupted in late July 2025 near the disputed areas surrounding the Preah Vihear Temple. Both sides agreed to an unconditional ceasefire on 7 August in Kuala Lumpur, brokered by Malaysia in its role as ASEAN chair. 

However, the truce remains fragile.

Philippines Takes the Helm in 2026

The Philippines will chair ASEAN in 2026 under the theme “Navigating Our Future, Together”. Foreign secretary Maria-Theresa Lazaro said Manila aims to maintain continuity, not reinvention, focusing on the three pillars of the ASEAN Community.

Priorities include advancing the long-delayed South China Sea Code of Conduct, climate action, and further steps on Myanmar-issues expected to dominate ASEAN’s agenda as geopolitical tensions persist.

Faiz Abdullah noted that Southeast Asia’s fortunes are increasingly tied to a complex global environment. 

“The lines between geopolitics and geoeconomics have blurred,” he said, warning that cooperation will be essential amid heightened uncertainty.

A New Beginning for ASEAN

Malaysia’s 2025 chairmanship reinforced the bloc’s foundations after years of cumulative work. But the next phase requires execution, not more frameworks.

ASEAN’s ability to act with clarity will be tested more than ever in 2026. The scaffolding has been strengthened; the region must now decide what to build on top of it.

Once-Monthly GLP-1 RA | Gan & Lee Pharmaceuticals Initiates Phase 3 Clinical Study (GRADUAL-3) of the First Chinese Once-Monthly GLP-1 RA for Weight Management

BEIJING, Nov. 27, 2025 /PRNewswire/ — Gan & Lee Pharmaceuticals (Gan & Lee, stock code: 603087.SH) announced the initiation of GRADUAL-3, its third large-scale phase 3 clinical study of the glucagon-like peptide-1 receptor agonist (GLP-1 RA) bofanglutide (research code: GZR18) injection in adults with obesity or overweight. In this study, bofanglutide injection will be administered subcutaneously once every four weeks (once-monthly) to explore its potential to maintain the achieved weight loss and improved long-term adherence.

This phase 3 study (Chinadrugtrials.org.cn: CTR20254659) is designed to evaluate the efficacy and safety of once-monthly bofanglutide injection on body weight after 24 weeks of continuous treatment. Professor Linong Ji from Peking University People’s Hospital is the leading principal investigator of the study. The primary endpoints were the change and the percentage change from baseline in body weight at Week 24.

Previously, Gan & Lee has conducted two phase 3 clinical studies (GRADUAL-1 and GRADUAL-2) of bofanglutide injection for weight management in adults with obesity or overweight. In GRADUAL-2 study, bofanglutide injection is the first GLP-1 RA globally to be evaluated in a head-to-head, parallel-group comparison with semaglutide 2.4 mg (Wegovy®) in Chinese adults with obesity or overweight, with or without type 2 diabetes. These studies are designed to comprehensively assess and confirm the efficacy and safety of bofanglutide injection in patients with obesity or overweight, as well as its overall impact on metabolic parameters and cardiovascular risk factors. The GRADUAL-3 clinical study will further explore the potential of once-monthly bofanglutide injection to maintain the achieved weight loss and improved long-term adherence. By reducing injection frequency and offering a more convenient treatment regimen, GRADUAL-3 is expected to support long-term treatment adherence and address key challenges associated with GLP-1 RA therapy, including weight regain and suboptimal durability of weight-loss efficacy over time.

GRADUAL Clinical Development Program
The GRADUAL clinical development program of bofanglutide injection is designed to comprehensively evaluate its efficacy and safety in adults with overweight or obesity. Three large-scale phase 3 clinical studies are currently ongoing in China, with a planned total enrollment of more than 1,000 participants.

  • GRADUAL-1 is a 52-week, phase 3 clinical study in approximately 630 Chinese adults with obesity or overweight who have not achieved adequate weight loss with diet and exercise, evaluating the weight-loss efficacy and safety of bofanglutide injection.
  • GRADUAL-2 is a 52-week, phase 3 clinical study in approximately 471 Chinese adults with obesity or overweight who have not achieved adequate weight loss with diet and exercise, with or without type 2 diabetes, assessing the weight-loss efficacy and safety of bofanglutide injection compared with Wegovy ® (semaglutide 2.4 mg, for weight management).
  • GRADUAL-3 is a 24-week, phase 3 clinical study designed to explore the efficacy and safety of once-monthly bofanglutide injection on maintaining weight-loss effect.

Bofanglutide injection
Bofanglutide injection (research code: GZR18) is a novel GLP-1 RA developed by Gan & Lee Pharmaceuticals. Its clinical development currently focuses on two indications: obesity/overweight and type 2 diabetes. Bofanglutide injection has demonstrated outstanding weight-loss and glucose-lowering effects in clinical studies, while also providing comprehensive metabolic benefits. The overall safety and tolerability profile of bofanglutide is consistent with that of marketed GLP-1 RAs. Currently, the global development of bofanglutide has advanced to the phase 3 stage.

Forward-looking statements
Forward-looking statements are based on our expectations and assumptions as of the date of the statements. Actual results may differ materially from those expressed in these forward-looking statements due to a variety of factors, and we can give no assurance that such results will be achieved in the future. We undertake no obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. 

Xinhua Silk Road: Exhibition on China’s Dehua white porcelain opens in Los Angeles

BEIJING, Nov. 27, 2025 /PRNewswire/ — An exhibition showcasing China’s Dehua white porcelain opened here Friday, drawing over 100 attendees from both countries and aiming to highlight traditional Chinese culture while promoting cross-cultural exchange.

Visitors view an artwork at an exhibition showcasing China's Dehua white porcelain in Los Angeles, the United States, Nov. 21, 2025. The exhibition opened here Friday, drawing over 100 attendees from both countries and aiming to highlight traditional Chinese culture while promoting cross-cultural exchange. Titled
Visitors view an artwork at an exhibition showcasing China’s Dehua white porcelain in Los Angeles, the United States, Nov. 21, 2025. The exhibition opened here Friday, drawing over 100 attendees from both countries and aiming to highlight traditional Chinese culture while promoting cross-cultural exchange. Titled “The Aesthetics of Harmony: Blanc de Chine, Porcelain from Dehua,” the exhibition featured around 100 finely crafted ceramic artworks and photographic pieces. (Photo by Qiu Chen/Xinhua)

The exhibition, titled “The Aesthetics of Harmony: Blanc de Chine, Porcelain from Dehua,” featured around 100 finely crafted ceramic artworks and photographic pieces. Blending traditional techniques with contemporary design concepts, the displays highlight the cultural legacy, artistic beauty and innovative spirit embodied in Dehua ceramics.

Addressing the event, Huang Hongjiang, deputy consul general of China in Los Angeles, said Dehua porcelain represents not only China’s long-standing cultural traditions but also its refined modern craftsmanship.

Huang said China’s upcoming 15th Five-Year Plan offers broad prospects for mutually beneficial cooperation with the United States in trade, investment and other areas, calling for joint efforts to increase exchanges and deliver more benefits to people in both countries.

Fang Junqin, head of Dehua County in southeast China’s Fujian Province, hoped that the exhibition will give the American public a chance to appreciate the elegance of Dehua porcelain and the Eastern aesthetic it embodies.

Fred Stehle, a local resident from Whittier in Los Angeles County, told Xinhua the porcelain pieces “are incredibly fine and delicate, rich in detail,” and reflect a blend of Chinese tradition, culture and modern craftsmanship.

“We’re very interested in Chinese culture and hope to learn more,” he said. “We also hope to visit China again in the near future.”

Original link: https://en.imsilkroad.com/p/348511.html

Laos Steps Up Debt Reforms With New Strategy, Stronger Oversight

Laos Steps Up Debt Reforms With New Strategy, Stronger Oversight
This image is used only for representational purpose (photo credit: pixabay/freemalaysiatoday)

Laos is advancing major public debt management reforms with a new medium-term strategy and tighter oversight of state-owned enterprises to strengthen fiscal stability and support economic growth, Deputy Minister of Finance Soulivath Souvannachoumkham said on 25 November.