Study highlights potential to produce a value-added lithium chemical at site, offering further opportunities to reduce logistics intensity over time and aligning with Canada’s and Québec’s objectives for domestic processing of critical minerals 

MONTREAL, June 15, 2026 /PRNewswire/ — June 15, 2026 – Sydney, Australia 

Highlights

• Concept study completed evaluating future potential to process spodumene concentrate into a value-added lithium product, directly at the Shaakichiuwaanaan site.
• Following a structured review of seven processing flowsheet options to produce a “value added” lithium product, the study identified Primero’s (NRW Holdings (ASX: NWH) subsidiary “Primero”) proprietary ALi® atmospheric leach processas the preferred value-added pathway for further study, given:
  • its overall economic potential, strong logistics efficiency benefits and technical risk profile, and
  • its alignment with the Company’s sustainability objectives through practicing environmental care in processing and minimizing the Project’s environmental footprint.
• Bench scale testwork on Shaakichiuwaanaan spodumene concentrate samples has been undertaken by Primero in Perth – Western Australia using the ALi® process, producing a 99.8% Li₂CO₃ battery-grade lithium carbonate.
• If combined with the use of electric calcination through Québec’s low-cost renewable energy, on-site value-added processing has future potential to reduce carbon intensity and improve efficiencies within the battery materials supply chain.
• Supports the Québec and Canada’s objectives for domestic, value-added processing, consistent with their respective Critical Minerals Strategies.
• The On-Site Refining Strategy is a staged, longer term, growth opportunity and is not required for the current proposed development of the base spodumene concentrate project outlined in the 2025 Feasibility Study.
• Next steps – future work expected to determine how to capture further economic benefits of value-added products at site including potential introduction of electrical calcination technology to leverage the full potential of Québec’s renewable and low-cost hydroelectric power.

Frederic Mercier-Langevin, Chief Operations/Development Officer for the Company comments: “Shaakichiuwaanaan is already a Tier-1 asset under our 2025 Feasibility Study, and this concept study potentially identifies a credible pathway to capture additional value on top of it. Converting spodumene concentrate to a “value added” and potentially battery-grade lithium chemical on-site could deliver a lower-cost, lower-carbon flowsheet powered by Québec hydroelectricity.

“Bench scale results on Shaakichiuwaanaan concentrates indicate battery-grade purity is potentially achievable and the logistics savings could be material. Importantly, subject to further test work and demonstration at scale being undertaken, this could be a staged value-add opportunity for Shaakichiuwaanaan for future development beyond the base spodumene project. Further study work now underway will continue to test and determine the path forward,” added Mr. Mercier-Langevin. 

Ken Brinsden, President, CEO & Managing Director comments: “For decades the industry has mined hard-rock lithium in one place and refined it in another, often overseas, which is hardly the most efficient supply chain solution. The work we’re reporting today points to the potential for a redefinition of the supply chain. It could be a credible alternate pathway, demonstrated at bench scale with our spodumene concentrates, to refine battery-grade lithium at the mine gate in a stable Western, low-carbon supply chain. This is the kind of industry step-change, supported by Shaakichiuwaanaan’s premier geology, that drew me to this Project.”

PMET Resources Inc. (the “Company” or “PMET”) (TSX: PMET) (ASX: PMT) (OTCQX: PMETF) (FSE: R9GA) is pleased to report on initiatives to develop value-added lithium chemical products at its 100%-owned Shaakichiuwaanaan Project (the “Project”), located in the Eeyou Istchee James Bay region of Quebec, Canada.

The Project’s 2025 Feasibility Study base case has already demonstrated the resource scale and grade that contributes to the low-cost of a spodumene concentrate produced at Shaakichiuwaanaan.¹ The Project also benefits from being adjacent to some of the lowest-cost renewable hydroelectric power in North America. With these strategic advantages as a backdrop, the Company is progressing the Project’s further assessment and development progress of its CV5 lithium-only project, with final mine authorization and extensive community consultation processes underway.

As part of its stated growth and diversification strategy to further add value to the Project, the Company has now completed a Concept Study assessing the potential to process spodumene concentrate into higher-value lithium chemical products directly at site. The work forms part of the Company’s broader long-term growth strategy to capture the potential additional value within the lithium supply chain while establishing a lower-carbon, Western-facing lithium chemicals platform in Québec. The Concept Study is based on low-level economic and technical assessments that are not sufficient to support the Company publishing production targets and economic outcomes or to provide assurance of an economic development case. The Concept Study does not constitute a preliminary economic assessment, pre-feasibility study, or feasibility study as defined under NI 43-101. Given the uncertainties involved, investors should not make any investment decision based solely on the results of the Concept Study.

A Potential redefinition of the North American Lithium Chemicals Supply

The Company believes the Shaakichiuwaanaan Project has the potential over its life to support an improved and more efficient lithium chemicals supply chain model, leveraging Québec’s abundant low-cost renewable hydroelectric power, strategic location within North America and proximity to key European and North American markets. Spodumene concentrate produced at Shaakichiuwaanaan is expected to be a raw material feed for a high-value chemical industry that is, to this day, largely conducted outside of Canada.

Producing a more concentrated, value-added lithia product on site is expected to provide the following benefits:

–  Redefine the lithium value chain model by locating electric calcination and some or all of the chemical conversion at the mine site, capturing significant logistical benefits by materially reducing shipped volumes and costs through the production of a concentrated higher lithia content product;

–  Leverage Québec’s renewable and low-cost hydroelectric power to support a lower-carbon lithium chemical supply chain, with the potential to enhance sustainability and materially reduce logistics-related emissions and fossil-fuel dependence;

–  Creation of a western-facing lithium chemical supply chain, supporting western mineral sovereignty and re-shoring value traditionally retained by downstream spodumene converters outside of Québec and Canada; and

–  Enhance Project value through the transformation of spodumene into a higher lithia content product that has the potential to command higher values and potentially broadening the Project’s customer-base.

Selecting the Process: Seven Options, One Preferred Pathway

The Company engaged Primero Group to complete a Concept Study to evaluate potential value-added processing routes for the spodumene concentrate produced at the Shaakichiuwaanaan Project. The primary objectives of the Study were to:

• Reduce the logistics associated with transporting 5.5% Li₂O Spodumene Concentrate (SC5.5) over long distances (844 km trucking to Matagami with subsequent 1,075 km rail route to shipping port);
• Evaluate whether producing an industrial or battery grade lithium chemical could improve market flexibility and project value; and
• Identify the most technically and economically robust processing route to progress into future study stages.

Phase 1 of the Study provided a concept level assessment of seven alternative flowsheets for chemical processing options, with the goal of narrowing down options to progress to a Phase 2 assessment, which focused on detailed refinement of product pathways. Within the Phase 2 assessment, both Acid Roast and Atmospheric Leach options were considered.

The Atmospheric Leach option (through Primero’s proprietary ALi® process) was found to deliver the strongest overall performance in the areas that most influence long-term Project value. At a conceptual level, it delivered the lowest comparable capital costs and operating costs, reagent and trucking burden, HSE and environmental risks and the shortest payback period with the highest overall potential financial return. Due to the preliminary nature of the Concept Study, Australian disclosure law prohibits the Company from presenting potential production and economic scenarios. Further detailed work is required before such information can be presented (see Next Steps – PEA Study below).  

ALi® Process Description

The ALi® flowsheet recovers lithium from beta spodumene through an atmospheric (low-pressure, lower-temperature) leach, stepping through ion exchange, before producing lithium carbonate by precipitation. Unlike the conventional high-temperature sulfuric acid roast that dominates hard-rock lithium refining, the atmospheric leach route is designed to operate with lower energy intensity, lower reagent consumption and resulting in a cleaner residue stream. Locating it at the mine gate keeps conversion close to the orebody and to the Project’s anticipated low-cost renewable power, regionalising a step in the supply chain that is conventionally performed offshore.

ALi® is one of a new generation of ‘acid-free’ lithium conversion flowsheets that replaces the conventional high-temperature sulfuric-acid roast (being the long-standing conventional industry route), with alkaline chemistry. The approach is designed to reduce reagent intensity and concentrated-acid handling, lower the process waste burden, while producing a more benign, potentially reusable residue.

In developing the ALi® process, Primero has processed several tonnes of 3rd party spodumene concentrate at its Pilot scale facility, producing several hundred kilograms of battery grade lithium carbonate. The same facilities have processed a smaller scale spodumene concentrate sample from Shaakichiuwaanaan to produce battery grade product, further supporting the proof of concept being applied by PMET to its downstream processing initiative.

The same acid-free approach (albeit leaching at high-pressure) is used at Tesla’s lithium refinery in Texas, the highest-profile commercial-scale example to date. Tesla refines spodumene at the chemical conversion facility in Texas, rather than shipping concentrate offshore for conversion. ALi® would apply that same principle at the Shaakichiuwaanaan mine gate, while targeting battery-grade lithium carbonate.

ALi® Process – Phase Two Testwork

As part of Phase 2 of the Concept Study, a bench-scale test program was conducted on approximately 10kg of an alpha spodumene lithium concentrate by ALS Metallurgy (Balcatta, Western Australia). The lithium concentrate used was generated from the dense media separation of material sourced from Shaakichiuwaanaan via the ApplePick program²

The concentrate was calcined (laboratory) at 1,050°C for 30 minutes, resulting in the conversion of 98.8% of the spodumene from the alpha to the beta phase. After milling, 2.2kg of the milled calcine was used for lithium extraction test work, utilizing Primero’s proprietary ALi® refining process (Figure 1 and Figure 2). The process resulted in a laboratory lithium extraction of 93.6%, based on beta spodumene lithium, with overall process recovery of 92.5%, inclusive of calcination.

A high-grade lithium carbonate product, prepared by crystallization of carbonate leach solutions was analysed by Intertek (Perth, Western Australia). The purity was found to be 99.8% Li₂CO₃, and all contaminants of concern were found to be well within 2023 Chinese standards for lithium carbonate³ tolerances, thereby potentially making the product suitable for battery grade carbonate.

Transport Logistics

By introducing the chemical conversion at the mine site, the Concept Study naturally identified the opportunity to significantly reduce transport and logistics costs, given the total tonnage of material to transport (both reagents and product) would be substantially reduced, leading to a natural reduction of the number of trucks on the road on a daily basis.

Further details pertaining to the overall value-added products assessment process and outcomes can be found in Appendix 1.

Next Steps – PEA Study

Based on the results outlined above, production of lithium carbonate using Primero’s ALi® Atmospheric Leach process was found to have the potential to deliver the most favorable overall Project outcome both from an economic and sustainability perspective. It combines strong relative economics compared to other options with lower operational complexity and the greatest improvement in logistics (both quantity and nature of material to be hauled over considerable distances).

The potential to generate a battery-grade product, commanding higher product value and improved marketability, represents meaningful upside that warrants advancing this flowsheet further. While the more conventional Acid Roast option remains a technically feasible alternative, its higher costs and risk profile and comparatively less beneficial logistics make it less attractive as the primary development path for operation at site.

The testwork completed to date has significantly advanced this potential value-add opportunity for the Shaakichiuwaanaan Project – which is already demonstrated as a Tier-1 lithium asset through the 2025 Feasibility Study – providing a compelling reason to continue with the initiative to unlock this additional upside. The next phase of work will therefore focus on advancing the Ali® process towards a PEA level of detail, inclusive of the following:

• Additional testwork to support flowsheet design and environmental testwork for residue characterization;
• Flowsheet development, including option to produce battery-grade lithium carbonate;
• Detailed logistics study, with the intent of fully fleshing out synergistic opportunities between inbound reagents and outbound product transport;
• Determination of residue management and disposal requirements, including investigation of potential to offset cement costs in underground mine pastefill based on pozzolanic properties of ALi® residue streams;
• The inclusion of electric calcination equipment (kiln) is expected to harness Québec’s renewable, low-cost hydro-electric power, lowering operating costs and further reducing the Project’s carbon footprint – building on the initial emissions benefits delivered through reduced trucking and fossil-fuel dependence.

The next phase of work is expected to be completed over the next calendar year and will inform whether, when and how the value-added products opportunity could potentially be integrated into the broader Shaakichiuwaanaan development plan in the future. The initiative is being advanced as a staged value-add growth opportunity and is not required for the current proposed development of the base spodumene concentrate project contemplated in the 2025 Feasibility Study.

Provided this next stage of work continues to support the potential for the application of the ALi® process at Shaakichiuwaanaan, further development steps, such as the deployment of the process at pilot-scale, would likely be required.

Qualified/Competent Person

The technical and scientific information in this news release that relates to the Mineral Resource  Estimate, and exploration results for the Company’s properties is based on, and fairly represents, information compiled by Mr. Darren L. Smith, M.Sc., P.Geo., who is a Qualified Person as defined by National Instrument 43-101 – Standards of Disclosure for Mineral Projects (“NI 43-101”), and member in good standing with the Ordre des Géologues du Québec (Geologist Permit number 01968), and with the Association of Professional Engineers and Geoscientists of Alberta (member number 87868). Mr. Smith has reviewed and approved the related technical information in this news release.

Mr. Smith is an Executive and Vice President of Exploration for PMET Resources Inc. and holds common shares, Restricted Share Units (RSUs), Performance Share Units (PSUs), and options in the Company.

The information in this news release that relates to the Mineral Reserve Estimate and Feasibility Study and the bench-scale testwork results is based on, and fairly represents, information compiled by Mr. Frédéric Mercier-Langevin, Ing. M.Sc., who is a Qualified Person as defined by NI 43-101, and member in good standing with the Ordre des Ingénieurs du Québec. Mr. Mercier-Langevin has reviewed and approved the related technical information in this news release.

Mr. Mercier-Langevin is the Chief Operating and Development Officer for PMET Resources Inc. and holds common shares, RSUs, PSUs, and options in the Company.

About PMET Resources Inc.

PMET Resources Inc. is a pegmatite critical mineral exploration and development company focused on advancing its district-scale 100%-owned Shaakichiuwaanaan Property located in the Eeyou Istchee James Bay region of Quebec, Canada, which is accessible year-round by all-season road and proximal to regional hydro-power infrastructure.

In late 2025, the Company announced a positive lithium-only Feasibility Study on the CV5 Pegmatite for the Shaakichiuwaanaan Property and declared a maiden Mineral Reserve of 84.3 Mt at 1.26% Li₂O (Probable)⁴. The study outlines the potential for a competitive and globally significant high-grade lithium project targeting up to ~800 ktpa spodumene concentrate using a simple Dense Media Separation (“DMS”) only process flowsheet. Further, the results highlight Shaakichiuwaanaan as a potential North American critical mineral powerhouse with significant opportunity for tantalum and caesium in addition to lithium.

The Project hosts a Consolidated Mineral Resource⁵ totaling 108.0 Mt at 1.40% Li₂O and 166 ppm Ta₂O₅ (Indicated) and 33.4 Mt at 1.33% Li₂O and 155 ppm Ta₂O₅ (Inferred), and ranks as a top ten lithium pegmatite globally in size. Additionally, the Project hosts the world’s largest pollucite-hosted caesium pegmatite Mineral Resource at the Rigel and Vega zones with 0.69 Mt at 4.40% Cs₂O (Indicated), and 1.70 Mt at 2.40% Cs₂O (Inferred).

For further information, please contact us at info@pmet.ca or by calling +1 (604) 279-8709, or visit www.pmet.ca. Please also refer to the Company’s continuous disclosure filings, available under its profile at www.sedarplus.ca and www.asx.com.au, for available exploration data.

This news release has been approved by

“KEN BRINSDEN”                                                         

Kenneth Brinsden, President, CEO, & Managing Director

Disclaimer for Forward-Looking Information

This news release contains “forward-looking statements” and “forward-looking information” within the meaning of applicable securities laws.

All statements, other than statements of present or historical facts, are forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and assumptions and accordingly, actual results could differ materially from those expressed or implied in such statements. You are hence cautioned not to place undue reliance on forward-looking statements. Forward-looking statements are typically identified by words such as “plan”, “development”, “growth”, “continued”, “intentions”, “expectations”, “emerging”, “evolving”, “strategy”, “opportunities”, “anticipated”, “trends”, “potential”, “outlook”, “ability”, “additional”, “on track”, “prospects”, “viability”, “estimated”, “reaches”, “enhancing”, “strengthen”, “target”, “believes”, “next steps” or variations of such words and phrases or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved. 

Forward-looking statements include, but are not limited to, statements concerning the potential to process spodumene concentrate into higher-value lithium chemical products directly at site, including expected recoveries and product quality, the potential for transport and other logistics cost reductions where spodumene concentrate is processed directly at site, the preparation and release of a preliminary economic assessment (PEA) with respect to the processing of spodumene concentrate at site within the next calendar year, the matters that such PEA will consider and the timing thereof, the Company’s long-term growth strategy to capture additional value within the lithium supply chain while establishing a lower-carbon, Western-facing lithium chemicals platform in Québec, the selection, advancement and potential commercial application of ALi®’s process principles at the Shaakichiuwaanaan Property, the potential Project outcome both from an economic and sustainability perspective by producing lithium carbonate using Primero’s ALi® Atmospheric Leach process, the potential to generate a battery-grade product at scale with enhanced marketability and value, the potential of on-site value-added processing to reduce carbon intensity and improve efficiencies within the battery materials supply chain, the Company’s plans to advance further technical studies, testwork, pilot-scale activities and engineering work, the potential integration of value-added processing into the Project’s development plan, obtaining the required authorizations, approvals and permits for processing facilities, the preliminary nature of the Concept Study and its ability to support further technical and economic evaluation , and the preparation and release of an updated Feasibility Study in the second half of 2026.

Forward-looking statements are based upon certain assumptions and other important factors that, if untrue, could cause actual results to be materially different from future results expressed or implied by such statements. There can be no assurance that forward-looking statements will prove to be accurate. Key assumptions upon which the Company’s forward-looking information is based include, without limitation, the ability of the Company to leverage Québec’s renewable and low-cost hydroelectric power and other required infrastructure, the ability of the Company to successfully develop, scale, operate and implement ALi® and its Atmospheric Leach option at the Shaakichiuwaanaan Property and the technical, economic and commercial viability of such process, that the results of the Concept Study and other testwork may be indicative of potential future performance, the Company’s ability to achieve battery-grade carbonate, the ability to achieve anticipated reduction in transportation costs, the accuracy of reserve and resource estimates, the classification of resources and the assumptions on which the reserve and resource estimates are based, long-term demand and pricing for lithium (spodumene), tantalum (tantalite), and caesium (pollucite) supply, that exploration and development results continue to support management’s current plans for the Shaakichiuwaanaan Property development, the availability and cost of reagents, consumables and equipment, the Company’s ability to obtain required authorizations, approvals and permits for value-added processing, that the Concept Study results, which are preliminary in nature and not based on a PEA or feasibility study, will support further advancement of the project and the ability of the Company to complete the proposed PEA.

Forward-looking statements are also subject to risks and uncertainties facing the Company’s business, any of which could have a material adverse effect on the Company’s business, financial condition, results of operations and growth prospects. Readers should review the detailed risk discussion in the Company’s most recent Annual Information Form filed on SEDAR+, for a fuller understanding of the risks and uncertainties that affect the Company’s business and operations.

Although the Company believes its expectations are based upon reasonable assumptions and has attempted to identify important factors that could cause actual actions, events or results to differ materially from those described in forward-looking statements, there may be other factors that cause actions, events or results not to be as anticipated, estimated or intended. There can be no assurance that forward-looking information will prove to be accurate. If any of the risks or uncertainties mentioned above, which are not exhaustive, materialize, actual results may vary materially from those anticipated in the forward-looking statements.

The forward-looking statements contained herein are made only as of the date hereof. The Company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except to the extent required by applicable law. The Company qualifies all of its forward-looking statements by these cautionary statements.

Competent Person Statement (ASX Listing Rules)

The information in this news release that relates to the Feasibility Study (“FS”) for the Shaakichiuwaanaan Project, which was first reported by the Company in a market announcement titled “PMET Resources Delivers Positive CV5 Lithium-Only Feasibility Study for its Large-Scale Shaakichiuwaanaan Project” dated October 20, 2025 (Montreal time) is available on the Company’s website at www.pmet.ca, on SEDAR+ at www.sedarplus.ca and on the ASX website at www.asx.com.au. The production target from the Feasibility Study referred to in this news release was reported by the Company in accordance with ASX Listing Rule 5.16 on the date of the original announcement. The Company confirms that, as of the date of this news release, all material assumptions and technical parameters underpinning the production target in the original announcement continue to apply and have not materially changed.

The Mineral Resource and Mineral Reserve Estimates in this release were first reported by the Company in accordance with ASX Listing Rules 5.8 and 5.9 in market announcements titled “World’s Largest Pollucite-Hosted Caesium Pegmatite Deposit” dated July 20, 2025 (Montreal time) and “PMET Resources Delivers Positive CV5 Lithium-Only Feasibility Study for its Large-Scale Shaakichiuwaanaan Project” dated October 20, 2025 (Montreal time) and are available on the Company’s website at www.pmet.ca, on SEDAR+ at www.sedarplus.ca and on the ASX website at www.asx.com.au. The Company confirms that, as of the date of this news release, it is not aware of any new information or data verified by the competent person that materially affects the information included in the relevant announcement and that all material assumptions and technical parameters underpinning the estimates in the relevant announcement continue to apply and have not materially changed. The Company confirms that, as at the date of this announcement, the form and context in which the competent person’s findings are presented have not been materially modified from the original market announcement.

Appendix 1 – JORC Code 2012 Table 1 (ASX Listing Rule 5.8.2)

Section 1 – Sampling Techniques and Data

Section 2 – Reporting of Exploration Results

APPENDIX 1

Phase 1: Options Assessment

Seven flowsheet options were evaluated across three processing routes (Acid Roast, Pressure Leach and Atmospheric Leach) as well as three different products (lithium carbonate, lithium sulfate and lithium phosphate).

Phase 1 provided a concept level comparison of all process options, with the goal of narrowing down options to progress to a Phase 2, focused on detailed refinement of product pathways.

The seven (7) options were evaluated using a multi-factor analysis using a combination of qualitative and quantitative factors:

• CapEx;
• OpEx;
• Product and Reagents Logistics;
• Reagent Sourcing and Availability;
• Technology Maturity;
• Recovery Risk;
• Flowsheet complexity;
• Product marketing;
• Residue Handling;
• Labour Availability.

The major project drivers – such as CAPEX, OPEX, technology maturity, product and reagent logistics and reagent sourcing – were assigned heavier relative weighting to reflect their increased influence on project viability. The remaining categories were considered secondary categories and assessed using a lighter relative weighing. Quantitative metrics were scored proportionally based on relative performance across the options, while qualitative criteria were evaluated using engineering judgement informed by industry precedent and operational experience.

Phase 1 shortlisted two lithium carbonate pathways to be advanced to the next stage for more detailed analysis; the Atmospheric Leach process achieved the highest score, with the Acid Roast process coming in second place.

Phase II: Concept Study

The Phase 2 design basis built upon the Phase 1 assumptions while incorporating updated process parameters. While Phase 1 assigned 100% lithium recovery to all options for concept–level comparability and to isolate CAPEX/OPEX and logistics differences, Phase 2 introduced more realistic recovery assumptions, with a lower recovery applied to the Atmospheric Leach option to account for the novel technology. This assumption affects consumptions, product mass, and trucking requirements.

Phase II Outcomes

Due to the preliminary nature of the Concept Study, Australian disclosure law prohibits the Company from presenting potential production and economic scenarios. Further detailed work is required before such information can be presented (see Next Steps – PEA Study above).

The reagent quantities were estimated using the refined recoveries and material balances and the logistics were re-evaluated for Phase 2, calculating the inbound (reagents) and outbound (product) transportation requirements for both options for comparison against the outbound-only transportation requirements of the spodumene concentrate (base case).

The Study outlined that, beyond the expected reduction in transportation costs due to the inherent significant drop in volume from concentrate to carbonate, the two options could capture varying degrees of synergies between outbound trucks leaving site with product and returning to site with reagents, synergies that do not exist under the base case where spodumene concentrate trucks leave the mine site full and return empty.

Based on the above, the Study concluded that introducing value-added products at the mine site could significantly reduce transport and logistics costs, given the total tonnage of material to transport (both reagents and product) would be substantially reduced, leading to a natural reduction of the number of trucks on the road on a daily basis.

The Atmospheric Leach option was found to deliver the strongest overall performance in the areas that most influence long-term project value, delivering the lowest capital costs, operating costs, reagent and trucking burden, HSE and environmental risks and the shortest payback period with the highest potential financial return.

Although the Acid Roast option benefits from greater process maturity and existing industrial references, these advantages are outweighed by its higher reagent demand, increased logistics requirements, more complex residue management, and higher sensitivity to market and operating conditions.

• The combination of selinexor plus ruxolitinib met the first co-primary endpoint demonstrating a statistically significant improvement of spleen volume reduction (SVR35) of 49.8% for the combination arm vs 28% for the control arm at week 24.
• Post-hoc analysis from the phase 3 SENTRY trial suggests SVR35 may predict overall survival (OS); new data from the phase 1 SENTRY trial demonstrates a similar finding.
• Data selected by EHA’s Scientific Program Committee for late-breaking oral presentation.
• Data stems from the pivotal study conducted in collaboration with Karyopharm Therapeutics, Inc.

FOR MEDICAL AND PHARMACEUTICAL TRADE MEDIA ONLY

FLORENCE, Italy and NEW YORK, June 14, 2026 /PRNewswire/ — The Menarini Group (“Menarini”), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. (“Stemline”), a wholly-owned subsidiary of the Menarini Group focused on bringing transformational oncology treatments to cancer patients, announced that new data related to the pivotal Phase 3 SENTRY trial will be presented as a late-breaking oral[i] at The European Hematology Association (EHA) 2026 Congress.

SENTRY (NCT04562389), a pivotal Phase 3 trial, is a randomized, double-blind, placebo-controlled trial of 60 mg selinexor in combination with ruxolitinib in frontline myelofibrosis (MF) (n=353), versus ruxolitinib monotherapy. Conducted by Karyopharm Therapeutics, Inc., in collaboration with the Menarini Group, SENTRY was designed to evaluate two co-primary endpoints: spleen volume reduction of 35% or more (SVR35) and absolute total symptom score (Abs-TSS).

The trial met the first co-primary endpoint, demonstrating that patients who were treated with the combination of selinexor plus ruxolitinib achieved a clear and statistically significant improvement in SVR35, compared to patients who received ruxolitinib alone. These results highlight that the combination arm enabled rapid, deep and sustained spleen volume reductions.

“Achievement of spleen reduction is the essential goal of myelofibrosis treatment. Importantly, the spleen reduction results seen in SENTRY were rapid, deep and durable, and associated with potential overall survival benefit for the patients receiving the combination,” said Dr. Claire Harrison, Professor of Myeloproliferative Neoplasms and Deputy Chief Medical Officer at Guy’s and St. Thomas’ NHS Foundation Trust. “We are encouraged that these results represent a potential new therapeutic advance for our patients who are in dire need of better options.”

Other key highlights include:

• Absolute Total Symptom Score (Abs-TSS): The combination arm demonstrated a comparable benefit to ruxolitinib alone, with a 9.9 point improvement in Abs-TSS at week 24, in patients who received the combination, compared to a 10.9 point improvement in patients who received ruxolitinib alone. The difference across the two arms was not statistically significant, and the combination arm did not meet this second co-primary endpoint.
• Overall Survival (OS): While these data were immature at the time of analysis, a promising early OS signal, a pre-specified secondary endpoint, was observed with the selinexor combination compared to ruxolitinib alone. The study showed a greater than 50% reduction in the risk of death for patients receiving the selinexor combination (HR 0.43).
• Spleen Volume Reduction: Consistent SVR35 benefit was observed across prespecified subgroups. Notably, at week 24, superior spleen volume reduction was achieved by the selinexor combination, regardless of the ruxolitinib dose, including by patients receiving less than 15 mg of ruxolitinib per day.
• Variant Allele Frequency (VAF) Reduction: This pre-specified exploratory endpoint, which is associated with SVR35, was observed in 32% of patients in the selinexor plus ruxolitinib arm at week 24 versus 23.9% of patients treated with ruxolitinib alone, indicating the combination’s potential for disease modification.
• Safety and Tolerability: The combination demonstrated a manageable safety and tolerability profile consistent with the known profile of selinexor and ruxolitinib individually. No new safety signals were observed.

“The strength of the spleen response and the encouraging early overall survival data observed in the SENTRY study creates hope for a potential new treatment option for patients suffering from this devastating disease with dismal outcomes,” said Elcin Barker Ergun, CEO of the Menarini Group. “Our dedication and commitment to bring transformational treatments to patients facing cancer is stronger than ever.”

About Myelofibrosis (MF)

Myelofibrosis (MF) is a type of blood cancer that belongs to a group of diseases called Myeloproliferative Neoplasms (MPNs). These diseases are caused by the overgrowth of abnormal blood-forming cells in the bone marrow, which leads to the formation of scar tissue. This scarring makes it difficult for the body to produce healthy blood cells. The incidence of MF is rare, with only about one or two people diagnosed each year for every 100,000 individuals, and the median survival after diagnosis is six years. Additionally, for people living with MF, their quality of life can be compromised by symptoms including fatigue, an enlarged spleen, and low blood counts, all of which are caused by the disease. ^1,2,3

To report SUSPECTED ADVERSE REACTIONS, contact Stemline Therapeutics, Inc. at adverseevents@menarinistemline.com. All of the relevant information can be found at https://stemline.com/contact/

Please see Summary of Product Characteristics (SmPC) and European Public Assessment Report at www.ec.europa.eu.

Please refer to local prescribing information where selinexor is approved for full information. Menarini Group holds licensing rights for selinexor and currently markets it in numerous European countries and global territories. In the U.S., Karyopharm Therapeutics markets selinexor and the full prescribing information is available here.

About The Menarini Group

The Menarini Group is a leading international pharmaceutical and diagnostics company, with a turnover of $5.5 billion and over 17,000 employees. Menarini is focused on therapeutic areas with high unmet needs with products for cardiology, oncology, pneumology, gastroenterology, infectious diseases, diabetology, inflammation, and analgesia. With 18 production sites and 9 Research and Development centers, Menarini’s products are available in 140 countries worldwide. For further information, please visit www.menarini.com.

About Stemline Therapeutics Inc.
Stemline Therapeutics, Inc. (“Stemline”), a wholly-owned subsidiary of the Menarini Group, is a commercial-stage biopharmaceutical company focused on bringing transformational oncology treatments to patients. Stemline commercializes elacestrant, an oral endocrine therapy indicated for the treatment of postmenopausal women or adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy, in the U.S., Europe, and other global regions. Stemline also commercializes tagraxofusp-erzs, a novel targeted therapy directed to CD123, for patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic cancer, in the United States, Europe, and other global regions. In addition, Stemline commercializes selinexor, an XPO1 inhibitor for multiple myeloma, in Europe. The company is also conducting multiple label-expansion studies with elacestrant and tagraxofusp in breast and hematologic cancer indications, respectively, and has an extensive clinical pipeline of additional drug candidates in various stages of development for a host of solid and hematologic cancers.

References

1.  Myelofibrosis. NORD (National Organization for Rare Disorders). https://rarediseases.org/mondo-disease/myelofibrosis/
2.  Myelofibrosis. The Leukemia & Lymphoma Society (LLS). https://bloodcancerunited.org/blood-cancer/myeloproliferative-neoplasms-mpns/myelofibrosis-mf
3.  Myelofibrosis. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/myelofibrosis/symptoms-causes/syc-20355057

^[i] The safety and efficacy of the investigational combinations and unapproved indications discussed in this press release have not been established by the FDA, EMA, or any other regulatory authority.

KUALA LUMPUR, Malaysia, June 14, 2026 /PRNewswire/ — Ddrops^®, a Canadian family health and nutritional supplement brand, participated as a supporting sponsor of Aqua Champs League Fest 2026 (ACLF 2026) in Malaysia, reinforcing its commitment to children’s healthy growth through active lifestyles, positive family routines and simple daily nutrition.

Organised by Parenthood and Swimin12, ACLF 2026 brought together young swimmers, parents, coaches and community partners for a day of youth swimming, family engagement and health-focused activities. The event encouraged children to stay active, build confidence in the water and experience the benefits of structured sports participation in a supportive community setting.

“At Ddrops^®, we believe healthy growth begins with the small habits families practise every day,” said a spokesperson for Ddrops^®. “Whether children are swimming, learning, playing or growing through each stage of childhood, they need support that fits naturally into family life. ACLF 2026 is exactly the kind of initiative we are proud to support because it encourages children to stay active, build confidence and develop positive health habits in a fun and memorable way.“

Throughout the event, families visited the Ddrops^® booth to learn more about children’s nutrition and practical ways to support daily wellness at home. Parents shared common concerns around children’s growth, bone health, immunity, picky eating and the challenges of maintaining consistent supplement routines, especially when children are sensitive to taste, texture or swallowing tablets.

Known for its “Just One Drop” approach to vitamin D supplementation, Ddrops^® offers convenient liquid formats designed to make daily nutrition easier, and can be added to food or drink without adding complexity to busy family routines. 

As part of the event, Ddrops^® sponsored the Champions Challenge Grand Prize, awarding one winning family with a full year’s supply of Ddrops^® nutritional products to support their family’s daily wellness journey.

Ddrops^®‘ participation coincides with an important brand milestone. Ddrops^® Kids Liquid Algae Calcium was recently recognised with the “Best Liquid Calcium Supplement for Kids” award at the Parenthood Parents’ Choice Awards 2026, reflecting growing consumer trust in child-friendly nutritional solutions that combine convenience, taste and daily wellness support.

As more families across Malaysia and Southeast Asia embrace active lifestyles and preventive health, Ddrops^® remains committed to supporting parents with science-backed, family-friendly nutritional solutions that help children build strong foundations for lifelong health and wellbeing.

CHONGQING, China, June 14, 2026 /PRNewswire/ — At the 28th Chongqing International Auto Exhibition, Changan Group showcased its full brand lineup including CHANGAN NEVO, CHANGAN DEEPAL and AVATR at Hall N8, and officially launched its self-developed Advanced Driver-Assistance System, SDA Pilot.

At the press conference, Zhu Huarong, Chairman of Changan Group, stated: “Changan will work together with partners and users worldwide to make ADAS better, more practical, and more accessible, protecting every journey with smart technology.” It is announced that the CHANGAN NEVO Q06 will come standard with SDA Pilot across all trim levels and hit its domestic market in the second half of 2026.

SDA Pilot Takes the Spotlight: Three-tier Safety Defenses Upgrade the ADAS Experience

As Changan’s latest technological achievement in smart mobility, SDA Pilot breaks the boundaries of traditional physical safety and establishes three comprehensive safety defense systems covering physical well-being, mental comfort and emotional interaction.

The entry-level SDA Pilot Pro comes standard with LiDAR, capable of identifying obstacles in low-light conditions such as at night or in tunnels two seconds faster than the human eye. Supported by the globally leading SDA Central Ring Network Architecture, the system cuts response time by an additional 150 milliseconds. SDA Pilot Max, leverages over 20 million high-quality real-world driving data segments for training, delivering exceptional perception and predictive capabilities to confidently navigate complex, high-frequency commuting scenarios. The top-tier SDA Pilot Ultra is integrated with the VLM (Vision Language Model), which greatly enhances the vehicle’s environmental perception and enables interactive advanced driver-assistance functions, turning the vehicle into an intuitive travel companion. In the future, an active driver incapacitation protection function will also be introduced to safeguard driving safety at the first moment.

While continuously evolving its ADAS user experience, Changan remains committed to its safety bottom line, clearly reminding: “Driver assistance is not autonomous driving. Drivers are still required to take on the core responsibilities of real-time monitoring and taking over control at any time.”

Advancing the “1445” Global Strategy: 17 Years of Intelligent R&D Build Solid Safety Foundations

Changan Group lives by the tenet of “Intelligence defines Changan.” As a core component of the “1445” Global Strategy that underpins four transformation priorities (The four priorities refer to: intelligent mobility, electrification, a unified ecosystem, and globalization), intelligent mobility stands as the primary driving force for Changan’s upgrading. The company is committed to building a world-class auto group with global competitiveness and independent core technologies, aiming to rank among the world’s top 10 automobile brands by 2030. The launch of SDA Pilot marks a landmark achievement of this strategy in the advanced driving-assistance sector.

Behind this technological breakthrough lies a solid intelligent foundation built by Changan over 17 years. Since establishing its intelligent R&D team in 2009, Changan has forged ahead in uncharted technological territories and built the China’s only national key laboratory dedicated to intelligent vehicle safety technology — CHANGAN SDA LAB. The lab supports round-the-clock global collaborative testing with more than 400,000 virtual simulation scenarios.

Over the past five years, more than 2,000 Changan engineers have completed over 5 million kilometers of real-road tests across Chongqing’s notoriously complex road conditions, covering 185 typical driving scenarios. Rich field experience has been embedded into the system, which keeps evolving based on user feedback and forms the unshakable safety strength of SDA Pilot.

Empowered by intelligent technologies, Changan continues to accelerate its global footprint. To date, the group has established 22 overseas manufacturing bases with an annual capacity of 350,000 vehicles, and 1,124 overseas sales outlets, covering 118 countries and regions, with 41 global models launched. In 2025, Changan’s overseas sales reached 637,000 vehicles, a year-on-year increase of 18.9%.

Since the start of 2026, Changan has made successive moves in its globalization strategy: launching the Vast Ocean Plan 2.0 during the AutoChina 2026 in Beijing, establishing four core principles: long-term development, localization, systematization, and responsible ESG practices; and more recently, partnering with the Portuguese Football Federation (FPF) to become the Official Global Partner of the Portugal National Football Team, using sports as a bond to deepen global user connections and brand engagement.

The “TAIWAN DESIGN POWER” Taiwan Pavilion, showcased at the Busan Design Festival in South Korea, brings together 25 design projects and 20 industry representatives, demonstrating Taiwan’s diverse design capabilities—from public service innovation and everyday-life solutions to brand development and market-driven design.

BUSAN, South Korea, June 14, 2026 /PRNewswire/ — Organized by the Industrial Development Administration, Ministry of Economic Affairs, and executed by the Taiwan Design Research Institute (TDRI), the TAIWAN DESIGN POWER Pavilion will be showcased at the Busan Design Festival 2026 in South Korea from June 11 to June 14. Centered around three themes—From Places to Experiences, From Needs to Solutions, and From Design to Market—the exhibition brings together 25 design projects and 20 industry partners, demonstrating how Taiwan leverages design to address public services, everyday needs, and market development.

From Places to Experiences: Design Driving Public Service Innovation

The exhibition features public design initiatives including the Taipei Main Station MRT Redesign, the Taiwan Public Pictogram System, and the Design Movement on Campus. These projects reflect TDRI’s long-term efforts to integrate design into public governance through cross-sector collaboration, creating more user-friendly, inclusive, and efficient public service environments.

From Needs to Solutions: Innovative Designs Inspired by Everyday Needs

Highlights include minica e-cargo bike, developed by GWA Energy, INC., a smart mobility solution designed for family transportation with enhanced safety, convenience, and cargo capacity; the Momax PinBuzz Rechargeable Anti-Theft Personal Alarm With Find My Locator, an Apple-certified device featuring a 100dB alarm, anti-theft vibration alerts, waterproof functionality, and built-in lighting; and the H h L Master Bowl | Dual-Layer Ant-Proof Pet Bowl, showcasing how design can transform everyday observations into practical solutions.

From Design to Market: From Cultural Creativity to Global Markets

The exhibition also showcases Taiwan brands successfully expanding internationally through cultural creativity, sustainability, and cross-disciplinary collaboration. Featured works include FILTER017®, which has entered overseas markets such as Japan and Hong Kong through international collaborations, cultural projects, and brand curation; and OR｜Persimmon Story – Persimmon-Shaped Lotos Silt & Areca Charcoal Aroma Stone by Grand Vision Co., Ltd., which combines reservoir sediment recycling technology, agricultural waste reutilization, and traditional Taiwanese persimmon dyeing techniques, highlighting Taiwan’s innovative approach to sustainable and culturally driven design.

In addition, the pavilion itself embodies circular design principles, utilizing a honeycomb paper system developed by Taiwanese brand The Young Square. The reusable and recyclable structure demonstrates Taiwan’s innovation in sustainable materials and exhibition design.

Student Design Showcase: Emerging Taiwanese Talent Takes the International Stage

In addition to professional design projects and industry collaborations, the Taiwan Pavilion also featured a dedicated Student Design Showcase. Curated by TDRI, the section presented nine outstanding works created by six Young Pin Design Award teams from four leading Taiwanese universities, including Ming Chi University of Technology, National Cheng Kung University, Fu Jen Catholic University, and National Taiwan University of Arts.

A total of 13 students traveled to Busan to participate in the exhibition, opening ceremony, and Taiwan–Korea student networking events. The showcase highlighted the creativity, innovation, and international potential of Taiwan’s next generation of designers. The student works attracted considerable attention from local media and visitors, while the enthusiastic participation and vibrant atmosphere throughout the exchange activities injected new momentum into Taiwan–Korea design collaboration.

TDRI President Highlights Taiwan’s Design-Driven Innovation at BUSAN GLOBAL DESIGN SEMINAR 2026

Among the highlights, Busan Global Design Seminar 2026, the international forum of the 2026 Busan Design Festival, was held on June 11, bringing together leading representatives from Taiwan, Korea, and the global design community to discuss how design can respond to contemporary social and everyday-life challenges. Chi-Yi Chang, President of the Taiwan Design Research Institute (TDRI), was invited by the Busan Design Center (DCB) as a keynote speaker and delivered a presentation titled “Design to Everyday Life.” In his talk, he shared how Taiwan leverages design in public services, urban governance, and daily life to create social value that is both inclusive and innovative.

According to TDRI, the exhibition aims to deepen Taiwan–Korea and international design exchanges while showcasing Taiwan’s comprehensive design capabilities—from public innovation to market applications—to a global audience.

Exhibition Information

Dates:
June 11–13, 2026 | 10:30 AM – 6:00 PM
June 14, 2026 | 10:30 AM – 5:00 PM

Venue:
Busan BEXCO 2nd Exhibition Hall
(30 APEC-ro, Haeundae-gu, Busan, South Korea)

Organizer: Industrial Development Administration, Ministry of Economic Affairs, Taiwan
Executive Organizer: Taiwan Design Research Institute (TDRI)

Exhibitor: GWA Energy, INC. , Momax Taiwan Co., LTD. , ORIGEN CULTURAL&CREATIVE CO., LTD. , Kiddie’s Paradise Inc. , B&B Best Industrial Co., Ltd , D. JIA International Ltd. , DOT DESIGN CO., LTD. , Grand Vision Co., Ltd. ,  Lupao Fine China Co. Ltd. , BLACK DESIGN CO.,LTD. , Lion Travel Service Co., Ltd. , YIN Operation , BAUJIE AGARWOOD , Yuan Xin Chi international CO.,LTD. , Maomaoyu Design Ltd. , Senmade Production Co., Ltd. , Kyoku Haku Co., Ltd. , WHITEFERN DESIGN LIMITED COMPANY , FILTER017® , KINGJUN

SHANGHAI, June 14, 2026 /PRNewswire/ — The Gala Night of the 28th Shanghai International Film Festival (SIFF) was held in Shanghai today, bringing together filmmakers, industry professionals and audiences from around the world in celebration of cinema.

Running through June 20, this year’s festival will present more than 420 films across over 1,600 screenings in Shanghai and cities throughout the Yangtze River Delta. As one of only 17 film festivals worldwide to hold official A-list classification from FIAPF, SIFF continues to serve as a major platform for international cinematic exchange.

The winners of the Golden Goblet Awards will be announced at the Golden Goblet Awards Ceremony of the 28th Shanghai International Film Festival on June 20.

A Night of Cinema Along the Huangpu River

The Gala Night transformed Shanghai into a vibrant stage for global cinema, welcoming filmmakers, actors and industry professionals from around the world. Golden Goblet Awards jurors, nominated filmmakers and representatives of major Chinese and international productions gathered on the red carpet, showcasing the festival’s growing international profile and influence.

One of the evening’s most significant moments was the presentation of the festival’s honorary awards. Renowned actress and cultural ambassador Lisa Lu received the Lifetime Achievement Award, while acclaimed Chinese director Zhang Yimou was honored with the Outstanding Contribution to Chinese Cinema Award, recognizing their exceptional achievements and enduring contributions to the development of cinema.

The celebration once again highlighted Shanghai’s unique role as a city where cinema, culture and international exchange converge.

Opening Film Afterpiece Makes World Premiere

This year’s opening film, Afterpiece, made its world premiere as one of the festival’s most anticipated events. Directed by Keane T.K. Wong and produced by Derek Yee, the film stars Stephen Fung, Chrissie Chau, Myolie Wu and Angela Yuen. The story follows a once-celebrated theatre director seeking creative redemption while navigating the increasingly blurred boundaries between performance and reality.

Developed under a Hong Kong film mentorship initiative pairing established filmmakers with emerging directors, Afterpiece reflects the continued transmission of creative talent across generations in Hong Kong cinema.

Members of the cast and creative team attended the Gala Night and participated in audience activities following the premiere screening.

International Jury Reflects Global Vision

Members of the Golden Goblet Awards jury met with the media in Shanghai ahead of this year’s festival activities, representing filmmakers and industry professionals from around the world.

The seven-member Main Competition jury is chaired by acclaimed actor Tony Leung Chiu-wai and includes Chinese director Guan Hu, actress Xin Zhilei, Tunisian producer Dora Bouchoucha, Kyrgyz director Aktan Arym Kubat, Georgian filmmaker Déa Kulumbegashvili and Mexican director Fernanda Valadez.

“It is a great honor to serve as jury president of the 28th Shanghai International Film Festival. Cinema is the art of dreaming, and Shanghai is the very vessel on which the Chinese film dream set sail. I hold a few more tickets for this voyage—would you like to join me?” said Tony Leung Chiu-wai.

The jury’s diverse composition reflects SIFF’s longstanding commitment to fostering dialogue among filmmakers from different cultures and creative traditions.

A Truly Global Stage for Cinema

This year, SIFF received approximately 4,100 submissions from 125 countries and regions, setting a new record in the festival’s history. Among nearly 3,000 eligible entries, 82 percent are world or international premieres, underscoring the festival’s growing global influence and appeal.

Audience enthusiasm remained strong, with online ticket sales launching on June 5 and 250,000 tickets sold within the first 15 minutes.

Beyond screenings, SIFF continues to promote international collaboration through initiatives including SIFF PROJECT, the International Film & TV Market, industry forums and masterclasses. The Belt and Road Film Festival Alliance, initiated by SIFF, now includes 57 member institutions from 50 countries, further strengthening cooperation among film communities worldwide.

Chen Guo, Managing Director of Shanghai International Film & TV Events Center, said: “Our goal is to use the festival platform to help films transcend geographic, linguistic and cultural boundaries, encouraging deeper cultural dialogue and creative exchange among filmmakers and audiences from different parts of the world.”

The International Film & TV Market will be held during the festival period, bringing together exhibitors, industry organizations and professionals from around the world to explore new opportunities in content creation, technological innovation and international cooperation.

For more information and the full festival schedule, please visit the official SIFF website at https://www.siff.com/english/