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Study Suggests Food Can Suppress Main Dengue Fever-Like Symptoms

Clinical trial confirms Kirin Holdings’ Lactococcus lactis strain Plasma effective against the cureless and vaccineless virus

TOKYO, JAPAN – Media OutReach – 17 September 2021 – A joint clinical trial confirmed that continuous intake of Kirin Holdings Company, Limited’s (Kirin Holdings) Lactococcus lactis strain Plasma (LC-Plasma)*1 for two months significantly reduced the cumulative number of days of fever, muscle pain, joint pain, and pain behind the eyes, which are known to be the main symptoms of dengue fever. LC-Plasma is the same functional ingredient in Kirin Holdings’ stable of IMMUSE material that help maintain the immune system. The study was conducted by The Kirin Central Research Institute in collaboration with Professor Dr. Sazaly Abu Bakar, Director of the Tropical Infectious Diseases Research & Education Centre (TIDREC) at the University of Malaya.

*1: Lactococcus lactis subsp. lactis JCM 5805 is owned by the RIKEN BioResource Research Center.

  • No Cure, No Vaccine… But Hope Against Symptoms Arises – In Food!

There is still no definitive cure or vaccine for dengue fever. However, the study results show there is hope for dealing with symptoms. The results of a clinical trial have confirmed the suppression of dengue fever-like symptoms through a food that is safe and does not rely on medical infrastructure, reflecting a groundbreaking achievement that has the potential to provide a solution to the global social issue of dengue fever. The results of this research were presented at the 25th Annual Meeting of the Japanese Society of Travel and Health on August 22.

Since LC-Plasma activates the command center of antiviral immunity, it has been shown to contribute to the prevention of a wide range of viral infections other than the dengue fever virus*2. Moving forward, Kirin Holdings and the University of Malaya will accelerate joint research aiming to verify the antiviral effects of LC-Plasma on tropical disease viruses other than the dengue virus.

*2: Lactococcus lactis strain Plasma Research Report https://health.kirin.co.jp/ps/index.html

 

Kirin Holdings has reported that LC-Plasma has shown immunostimulatory effects in the body’s defense against viral infections through activation of plasmacytoid dendritic cells*3 in non-clinical and clinical trials, and that LC-Plasma can reduce the incidence of influenza*4 in clinical trials. In collaboration with TIDREC, a WHO Collaborating Centre for Arbovirus Reference and Research, our collaboration will continue to verify the effects of LC-Plasma on other tropical infectious diseases, which are expected to expand further due to global warming. In tandem, Kirin Holdings will make LC-Plasma more accessible to more people in Southeast Asia through alliances and business expansion, providing a solution to a major social issue.

*3: Jounai et al., PLoS One (2012) / Sugimura et al., Clin. Immunol (2013)

*4: Sakata et al., Health (2017)

[Attachments]

1. Dengue Fever Joint Research Results Summary (1 page)

ATTACHMENT

 

DENGUE FEVER JOINT RESEARCH RESULTS SUMMARY

Clinical trial

According to the previous research outcomes performed by Kirin Holdings Company Limited*5, the Kirin Central Research Institute at Kirin Holdings Company Limited and the Tropical Infectious Diseases Research and Education Center (TIDREC) at the University of Malaya collaborated on a joint research project on Lactococcus lactis strain Plasma (LC-Plasma) against dengue fever from December 2019 to February 2020. During this time, approximately 100 healthy adults of Malaysian nationality living in dengue infection cluster areas near Kuala Lumpur, Malaysia, were asked to take a tablet containing LC-Plasma (approximately 100 billion cells) or a placebo for 8 weeks, and symptoms were measured. The results showed that LC-Plasma significantly reduced the cumulative number of days with dengue fever-like symptoms such as headache, joint pain, and pain behind the eyes (Figures 1-3). These results suggest that LC-Plasma, a food product, can help alleviate the symptoms and prevent the severity of the disease, while the only other option currently available for dengue fever is coping therapy.

Figs. 1-3 Comparison of the cumulative number of days of occurrence of symptoms specific to tropical diseases such as dengue fever(Representative symptoms)

*5: Tsuji et al., Antiviral Res (2018) / Suzuki et al., Int J Mol Med. (2019)

Outline of Collaborative Research

  • Location: Laboratory for Immuno-Regulation Studies, Tropical Infectious Disease Research and Education Centre (TIDREC), University of Malaya
  • Visiting Fellow: One Research Fellow appointed as visiting professor from Kirin Holdings Company, Limited.
  • Research Period: From the end of 2021 to December 2023 (thereafter, the period will be extended as the project and research progress)
  • Research Topics: Conduct immunological research on tropical infectious diseases in order to , to contribute to public health in the region and accelerate the overseas business development of Kirin Holdings’ health science business by:
    –  Confirmation of the efficacy of LC-Plasma against tropical disease viruses (non-clinical research). Confirmation of the efficacy of LC-Plasma against tropical disease virus infection  (clinical trials).
    –  Confirmation of the efficacy of LC-Plasma against tropical disease virus infection  (clinical trials).
    –  Research support for LC-Plasma business development in Southeast Asia region.

About Kirin Holdings

Kirin Holdings Company, Limited is an international company that operates in the Food & Beverages domain (Food & Beverages businesses), Pharmaceuticals domain (Pharmaceuticals businesses), and Health Science domain (Health Science business), both in Japan and across the globe.

Kirin Holdings can trace its roots to Japan Brewery which was established in 1885. Japan Brewery became Kirin Brewery in 1907. Since then, the company expanded its business with fermentation and biotechnology as its core technologies, and entered the pharmaceutical business in the 1980s, all of which continue to be global growth centers. In 2007, Kirin Holdings was established as a pure holding company and is currently focusing on boosting its Health Science domain.

Under the Kirin Group Vision 2027 (KV 2027), a long-term management plan launched in 2019, the Kirin Group aims to become “A global leader in CSV*, creating value across our world of Food & Beverages to Pharmaceuticals.” Going forward, the Kirin Group will continue to leverage its strengths to create both social and economic value through its businesses, with the aim of achieving sustainable growth in corporate value.

* Creating Shared Value: combined added value for consumers as well as for society at large.

#KirinHoldings

Singapore to Trial Import of Electricity from Laos

Singapore

Singapore is to trial the import of electricity from Laos via Thailand and Malaysia following an agreement between Keppel Electric and Electricite du Laos (EDL).

Cushman & Wakefield First Named Top Real Estate Advisor Globally, in Asia Pacific & Greater China by Euromoney

Cushman & Wakefield Hong Kong has ranked first in categories of “Overall Agency”, “Valuation”, “Letting/Sales” and “Research” for two consecutive years

HONG KONG SAR – Media OutReach – 16 September 2021 – Cushman & Wakefield, a leading global real estate services firm, has recently announced that the firm has been named the world’s top commercial real estate advisor and consultant for the fourth consecutive year in the Euromoney Real Estate Survey. This marks the first time for the firm to be awarded a clean swamp of Number Ones in Greater China, Asia Pacific, and worldwide, in all four categories of “Overall Agency”, “Valuation”, “Letting / Sales”, and “Research”.

 

Cushman & Wakefield Hong Kong

Cushman & Wakefield Hong Kong team is the only commercial real estate advisor and consultant that has been recognized as the top in the industry in categories of “Overall Agency”, “Valuation”, “Letting/Sales” and “Research” for two consecutive years.

 

John Siu, Managing Director, Hong Kong, Cushman & Wakefield, said, “We are honoured to win numerous awards in the 2021 Euromoney Real Estate Survey. Thanks to the endeavor of our teams for this significant achievement. We will uphold our customer-oriented principle and continue our provision of professional and high-quality services to assist our customers’ business growth”.

 

Cushman & Wakefield Greater China

Cushman & Wakefield Greater China team (including China, Hong Kong and Taiwan) was named the top real estate advisor and consultant in all four categories. In fact, China team alone has ranked first in all categories for the past years and entitled as “the top CRE advisor and consultant in China”.

 

KK Chiu, Chief Executive, Greater China, Cushman & Wakefield, said “We’re honored that Euromoney has now named Cushman & Wakefield the top CRE advisor and consultant in China, with Number One ranking across all categories. This is a testament to our culture of excellence and market-leading position across Greater China. Going forward, we will further focus on our clients’ needs and ensure that we continue to set the highest industry standards as we continue to grow in this important market”.

 

Louise Bowman, Euromoney editor, said “The Euromoney real estate awards are voted for by all constituents in the industry — developers, advisers and banks. This makes them of particular importance in recognizing strength in each individual sector. We congratulate Cushman & Wakefield for their achievement in winning Best Global Overall real estate Advisers and Consultants for the fourth consecutive year; and for earning the respect of their peers and colleagues in the highly competitive global real estate market.”

Euromoney 2021 Real Estate Survey

Euromoney’s 17th annual survey canvassed the opinions of leading firms involved in the real estate sector worldwide to determine which firms they believed to be the best providers of real estate products and services in their market during the past 12 months. Advisers, developers, investment managers, banks and corporate end-users of real estate were invited to take the survey. The full results are published on www.euromoney.com.  

 

About Cushman & Wakefield

Cushman & Wakefield (NYSE: CWK) is a leading global real estate services firm that delivers exceptional value for real estate occupiers and owners. Cushman & Wakefield is among the largest real estate services firms in the world, with approximately 50,000 employees in over 400 offices and 60 countries. In Greater China, a network of 22 offices serves local markets across the region, earning recognition and winning multiple awards for industry-leading performance. The firm had global revenues of $7.8 billion in 2020 across core services including valuation, consulting, project & development services, capital markets, project & occupier services, industrial & logistics, retail and others. To learn more, visit www.cushmanwakefield.com or follow us on LinkedIn (https://www.linkedin.com/company/cushman-&-wakefield-greater-china)

#Cushman&Wakefield

Pearl FALCO Launches Kickstarter Project ‘Pearl of Hope’ to Help the Underprivileged Children

SINGAPORE – Media OutReach – 16 September 2021 – Pearl FALCO today announced the launch of its annual Kickstarter initiative, Pearl of Hope, to create educational opportunities for underprivileged children in the Philippines and Himalayas.

It is hoped that this initiative empowers the children to reach their full potential and excel in school by providing them with tuition assistance. Donors will be able to help change a child’s future with the purchase of Pearl FALCO Jewellery. Through this initiative, 10% of the proceeds from each purchase will go directly to the “Pearl of Hope” fund.

Maiko Makito, Owner and Managing Director of Pearl FALCO, commented, “This campaign complements Pearl FALCO’s corporate social responsibility (CSR) objective and commitment to provide financial assistance to the less-privileged children especially at a turbulent time like this. Education offers children the best pathway to a better life and no child should to be denied that opportunity regardless of their present circumstances. Through Pearl of Hope, we hope to provide more educational opportunities to the children for them to pursue their dreams, now and in the future.”

“We are extremely excited with this year’s Pearl of Hope Challenge, knowing that it will be timely for the Christmas season, as a gift to the children. We hope this year will be a fantastic experience for all of those taking part and raise more funds for a wonderful cause.” She added.

 

Since its inception in 1987, the Pearl of Hope campaign has granted more than 50 educational scholarships to underserved children all over Asia. Many of Pearl FALCO team members have donated to the program from their own salaries and the team in Ise Japan also includes recipients of the grant who have graduated from college.

 

With this campaign, Pearl FALCO also hopes to connect Ise Shima, the birthplace of cultured pearls, with the rest of the world, helping more people learn about timeless pearl jewellery.

 

How The Pearl Of Hope Challenge Works

 

Each Pearl FALCO necklace contains 50 pieces of 8mm Akoya pearls, with a total value of S$4250. With that, 1 Akoya pearl is approximately S$85. Each donor may choose the number of pearls they would like to purchase, making the Pearl of Hope campaign affordable for everyone.

 

For more information on Pearl of Hope, please visit https://www.kickstarter.com/projects/pearlfalco/beautiful-luxury-pearls-from-japan-share-a-pearl-of-hope

 

#PearlFALCO

Taskforce Issues New Covid-19 Prevention Guidelines for Funerals

Funeral

Authorities in Laos have issued guidelines for the attendance of funerals across the country, stating that  Covid-19 prevention measures must be strictly followed.

StaffAny Announces the Launch of Sales-based Scheduling, a New Product Feature for Managers and HR to Schedule Based on Sales and Labour Productivity Goals

SINGAPORE – Media OutReach – 16 September 2021 – StaffAny, a staff scheduling, clock-in and timesheets tool, has just launched their latest upgrade: Sales-based Scheduling.

Businesses can now look forward to planning schedules with their sales goals in mind / that support their sales goals. This comes on top of the existing benefits StaffAny scheduling provides, such as up to 70% time saved in planning schedules, visibility on scheduled labour costs and instant team communication on schedule updates via the StaffAny app.

Sales-based scheduling enables managers to visualise target sales on a 30-minute interval basis against manpower coverage in a day. This helps managers plan schedules more efficiently, by avoiding over-scheduling during low peak periods, and still ensuring sufficient coverage by not under-scheduling.

 

As an added advantage, the new feature also allows teams to input actual sales, so businesses can compare actual vs. target sales. Using this data, they can plan target sales more accurately in the future.


With sales data, businesses are also better able to understand their labour productivity in terms of Sales per Labour Hour (SPLH). When the actual SPLH is less than the target SPLH, managers have the option to reduce the staff or motivate them to reach more sales. If the actual SPLH is higher than the target SPLH (benchmark), the target is met and overscheduling is averted. Managers can also spur productivity by setting SPLH targets for managers and standardising that across outlets.

 

Ultimately, businesses are in a better position to hit their sales goals, and can also easily compare Sales, Labour Hours and Productivity Metrics using StaffAny reports to make data-driven decisions.


The solution offers HR not just time saving benefits, pure labour cost savings of up to 3% but most importantly alignment with business revenue goals. StaffAny supports tens of thousands of users in the hourly work industry across countries such as Singapore, Malaysia, Vietnam, Indonesia and more.  


About StaffAny

StaffAny is a software-as-a-service that helps business owners reduce work dedicated to scheduling and time-tracking, as well as reduce the cost of operations by minimising time theft and overtime spend.

The solution is designed specifically for hourly workers as well as the gig economy. Key verticals served include F&B, Retail, Events and Healthcare. Successful case studies include large chains such as Royal T Group and Kiosks Collective, as well as small business owners such as Good Luck Beerhouse and Foreword Coffee.

Visit https://www.staffany.com/ to find out more.

#StaffAny

Laos Records 131 New Community Cases of Covid-19

Covid-19 update Khammouane

The Covid Taskforce reported that 5,270 tests were conducted over the last 24 hours, with 154 new cases of Covid-19 recorded.

GBG Named to Prestigious IDC FinTech Top 100 Rankings List

Ranking marks GBG’s inaugural participation in the distinguished list

SINGAPORE – Media OutReach – 16 September 2021 GBG (AIM:GBG), the global expert in digital identity, helping businesses prevent fraud and meet complex compliance requirements, today announces its inaugural placement as one of the top 100 financial technology providers around the globe by IDC Financial Insights, coming in at 66th position on the 2021 IDC FinTech Rankings.

 

GBG’s long-standing focus and success with the financial services industry, coupled with its record financial year performance earned GBG a coveted spot as a new entrant to the 2021 IDC FinTech Rankings.

Dev Dhiman, Managing Director, APAC, says, “It’s an honour to be recognised as a new entrant amongst the top 100 fintech providers around the world. For over 30 years, GBG has served more than 20,000 customers across the globe across 70 countries, including top tier banks and fintechs in APAC. We have grown and expanded rapidly to stay abreast of rapid digital disruption and the increasing focus in AI, cloud, financial inclusion, and cross-vertical collaboration in the financial services industry.”

 

“GBG has upscaled and modernised our end-to-end suite of identity verification, fraud detection, and compliance technology to manage the complexity and volume of today’s financial crimes, to ensure banks and fintechs are enabled with agile and dynamic solutions to create better customer experience for consumers to onboard and transact with them.”

 

“This recognition is testament to our commitment to deliver seamless, real-time activation of enriched solutions to help manage emerging financial crimes better. Today, GBG’s solutions are trusted by companies large and small to make digital living simpler and safer for businesses and consumers alike,” concludes Dhiman.

 

The 18th annual vendor ranking represents the leading hardware, software, and service providers to the financial services industry from around the world. The Fortune 500-style ranking categorises and evaluates the top global providers of financial technology based on calendar year revenues from financial institutions for hardware, software and/or services. These providers supply the technological backbone of the financial services industry, an industry in which IDC Financial Insights forecasts worldwide spending on IT across the globe to be $590 billion (USD) by 2025.

 

The inaugural placement on the 2021 IDC FinTech Rankings is the latest in a string of successes for GBG. These include:

“Being named in the IDC FinTech Rankings is a significant accomplishment, demonstrating a provider’s commitment to the success of its financial institution clients,” states Marc DeCastro, Research Director at IDC Financial Insights. “The IDC Fintech Rankings, now in its 18th year, is the global standard list of fintech providers to the industry, and we congratulate the 2021 winners.”

About GBG

GBG (AIM: GBG) offers a range of solutions that help organisations quickly validate and verify the identity and location of their customers. Our market-leading technology, data and expertise help our customers improve digital access, deliver a seamless experience and establish trust so that they can transact quickly, safely and securely with their customers online. Headquartered in the UK and with over 1,000 team members across 16 countries, we work with 20,000 customers in over 70 countries. Some of the world’s best-known businesses rely on GBG to provide digital services and keep the economy moving, from US e-commerce giants to Asia’s biggest banks and European household brands. To find out more about how we help our clients establish trust with their customers, visit www.gbgplc.com/apac, follow us on Twitter @gbgplc or LinkedIn.

#GBG