Results demonstrate a favorable safety profile and functional improvements in patients with severe tricuspid regurgitation including patients with reduced right ventricle function

YOKNEAM, Israel, Jan. 21, 2026 /PRNewswire/ — Trisol Medical, a clinical-stage medical device company developing a transcatheter tricuspid valve replacement system, today announced positive results from its FDA-approved U.S. Early Feasibility Study evaluating the Trisol Transcatheter Tricuspid Valve in patients with severe to torrential tricuspid regurgitation.

Illustration of Trisol Medical’s transcatheter tricuspid valve replacement system used in the company’s U.S. Early Feasibility Study for patients with severe to torrential tricuspid regurgitation.

Trisol’s Transcatheter Tricuspid Valve Replacement (TTVR) system is designed to treat severe to torrential tricuspid regurgitation (TR), a condition in which the tricuspid valve fails to close properly, allowing blood to flow backward from the right ventricle to the right atrium. Patients with this condition often have limited treatment options.

To date, 22 patients with severe to torrential TR who were considered high risk for conventional surgery have been treated at leading U.S. centers, including Piedmont Heart Institute, Vanderbilt University Medical Center, University of Virginia Health System, Columbia University Medical Center, and Cedars-Sinai Medical Center, using a trans-jugular (TJ) access approach. Enrollment in the TJ cohort is now complete, and the study is proceeding with continued enrollment using Trisol’s newly developed trans-femoral access route.

Key Study Results

• Safety: Less than 5% need for permanent pacemaker at 30-day follow-up. 
• Effectiveness: Considerable reduction in TR following implantation. 
• Functional outcomes: At 30-day and 12-month follow-up, notable improvements were observed in quality of life (KCCQ), heart failure symptoms (NYHA class), 6-minute walk distance, right ventricular function, and cardiac output. 
• Technical performance: Successful deployment of the device and no incidents of migration.

Importantly, these encouraging results include patients with reduced right ventricular function, a large, high-risk subgroup associated with poorer outcomes and underserved by existing and emerging treatment approaches. Early clinical experience reported to date across emerging therapies highlights a persistent unmet need in this patient population, suggesting the Trisol valve could help address this critical gap.

Dr. Pradeep Yadav commented: “Trisol brings several novel features from ease of use to recapturable anchors, broad size range, lower pacemaker rate and performance in dysfunctional right ventricles. We are very excited to investigate the next phase with its transfemoral delivery system and pivotal trial.”

“We are thrilled by these positive outcomes, which further validate the potential of our best-in-class technology to improve care for patients with severe TR. I would like to thank our clinical investigators and the entire clinical teams for their dedication and outstanding patient care,” said Ron Davidson, CEO of Trisol Medical.

Dr. Shimon Eckhouse, Chairman of Trisol, added: “Millions of Americans suffer from TR, and despite recent advances, effective treatment options remain limited for patients with severe TR. The Trisol valve was developed to address this significant unmet need and has the potential to redefine the standard of care.”

About Trisol Medical

Trisol Medical Ltd. is a clinical-stage medical device company specializing in the development of a novel TTVR. Founded within the Alon MedTech Ventures incubator, Trisol is dedicated to advancing minimally invasive heart valve therapies that offer safer alternatives to traditional surgical procedures. For further details, please visit: www.trisol-medical.com.

Media contact:
Ron Davidson
CEO
rond@trisol-medical.com

WASHINGTON, Jan. 21, 2026 /PRNewswire/ — The Drug Information Association (DIA) today announced the launch of DIA ASCENT, a new global platform designed to support early-stage biotechnology drug development innovation, along with its inaugural initiative, the LIFT (Linking Innovation, Funding, and Translation) Series. Together, ASCENT and LIFT create a structured, multi-stage pathway to educate, prepare, and connect emerging biotech and startup companies with investors, regulators, pharma leaders, and development organizations across the full product lifecycle.

Built to address persistent barriers facing early-stage innovators, such as limited investor access, fragmented access to expertise, and unclear regulatory pathways, and steep execution gaps, ASCENT extends DIA’s role as a trusted, multi-stakeholder convener to the earliest phases of innovation. Through curated education, mentorship, regulatory insight, and global exposure, the platform aims to strengthen the life sciences innovation pipeline worldwide.

The DIA LIFT Series unfolds across three integrated program offerings in 2026. Phase I launches with a Virtual Masterclass Series beginning in February 2026, featuring expert-led sessions with case studies focused on fund-raising, drug development including the role of AI, regulatory strategy, clinical development and financial modeling.

Phase II brings LIFT Series to DIA Europe 2026 in Rotterdam, Netherlands (March 24–26, 2026), with dedicated LIFT Programming for Biotech & Startups embedded within a globally attended meeting of more than 2,500 professionals. Programming includes expert coaching, live pitch competitions, regulator and investor roundtables, and curated networking opportunities.

Phase III culminates at the DIA 2026 Global Annual Meeting  in Philadelphia, Pennsylvania (June 14–18, 2026), featuring expanded LIFT Series Biotech & Startup programming, a Startup Row, and two targeted pitch events focused on drug and therapy development and techbio innovation, all within a 4,000+ attendee global forum.

“Our mission has always been to convene the global life sciences community to improve health worldwide,” said Marwan Fathallah, CEO of DIA. “With ASCENT and the LIFT Series Program, we are extending that mission earlier in the innovation journey providing emerging companies with the insight, connections, and visibility needed to advance promising science and strengthen the entire ecosystem.”

Registration for the LIFT Virtual Masterclass Series is now open. Details for Annual Meeting registrations and pitch competitions is available with pitch applications opening soon.

To learn more, visit: https://connect.diaglobal.org/dia-ascent-1

About DIA

DIA is a leading global non-profit life science membership association that drives collaboration in drug, device, and diagnostics development in pursuit of a healthier world. Founded in 1964 with headquarters in Washington, D.C., and offices in Europe and Asia, DIA provides unparalleled networking opportunities, educational resources, scientific research publications, and professional development programs to members in more than 80 countries.

Learn more at DIAglobal.org.

Contracts Expected to Increase YY Circle HK Monthly Revenue by 700-800%

New Partnerships Advance Regional Expansion Strategy and Further Diversify Revenue Streams

SINGAPORE, Jan. 21, 2026 /PRNewswire/ — YY Group Holding Limited (NASDAQ: YYGH) (“YY Group” or the “Company”), a global leader in on-demand workforce solutions and integrated facilities management (IFM), today announced that its Hong Kong subsidiary, YY Circle HK, has initiated service on casual staffing agreements with 12 premier hotels across Hong Kong, including 10 new partners and two previously announced properties under a leading Hong Kong hotel group. These new partnerships significantly broaden YY Group’s hospitality footprint in the region and contribute meaningfully to the Company’s growing base of recurring, contract-driven revenue, with an expected increase of 700-800% in monthly revenue from YY Circle HK starting in February 2026.

With the addition of these hotels, YY Circle HK’s client network now encompasses over 30 hotels and catering groups in Hong Kong, representing a robust 150% year-over-year increase and demonstrating the Company’s accelerating market penetration in one of Asia’s top hospitality hubs. Across the 12 properties, YY Circle HK expects to deliver tens of thousands of worker assignments annually in areas such as housekeeping, front office, F&B service, concierge operations, and recreational facilities.

These high-volume, multi-department engagements broaden the Company’s revenue base and enhance visibility into future operating performance. The growing scale of YY Circle HK’s hospitality business also strengthens operating leverage, as technology-driven deployment improves both efficiency and margin potential across the Company’s regional operations.

“We are pleased to deepen our presence in Hong Kong with another meaningful step forward in our hospitality expansion,” said Mike Fu, Chief Executive Officer of YY Group Holding Limited. “The addition of these premier hotels reflects the trust the industry places in our scalable and technology-driven labor solutions. As we continue to expand across Asia, these partnerships will provide long-term, predictable revenue streams that enhance our growth outlook, accelerating our development while creating value for our clients and shareholders.”

Anthony Ip, Co-founder and Country Director of YY Circle HK, added, “Partnering with this group of esteemed hotels represents a significant milestone for YY Circle HK in just our third year of operation, highlighting our growing reputation for excellence. Supported by YY Group’s advanced tech and extensive labor pool, we are uniquely equipped to deliver professionally trained manpower at scale and solve hospitality’s most complex staffing challenges. We look forward to empowering these local partners and further strengthening our brand presence across the Hong Kong market.”

Hong Kong’s casual labor sector is experiencing a demand surge driven by policy changes and favorable economic conditions. As hospitality operators seek more agile and efficient workforce solutions, YY Group’s flexible deployment capabilities, advanced workforce-management technology, and broad geographic scale position the Company to capture growing demand and capitalize on rising opportunities in Hong Kong and beyond.

About YY Holdings Limited

YY Group Holding Limited (Nasdaq: YYGH) is a Singapore-headquartered, technology-enabled platform providing flexible, scalable workforce solutions and integrated facility management (IFM) services across Asia and beyond. The Group operates through two core verticals: on-demand staffing and IFM, delivering agile, reliable support to industries such as hospitality, logistics, retail, and healthcare.

Leveraging proprietary digital platforms and IoT-driven systems, YY Group enables clients to meet fluctuating labor demands and maintain high-performance environments. In addition to its core operations in Singapore and Malaysia, the Group maintains a growing presence in Asia, Europe, Africa, Oceania and the Middle East.

Listed on the Nasdaq Capital Market, YY Group is committed to service excellence, operational innovation, and long-term value creation for clients and shareholders.

For more information on the Company, please visit https://yygroupholding.com/.

Safe Harbor Statement

This press release contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. Statements that are not historical facts, including statements about the YY Group Holding Limited’s beliefs and expectations, are forward-looking statements. Forward-looking statements involve inherent risks and uncertainties, and a number of factors could cause actual results to differ materially from those contained in any forward-looking statement. These factors include, but are not limited to, (i) growth of the hospitality market in Hong Kong, (ii) capital and credit market volatility, (iii) local and global economic conditions, (iv) our anticipated growth strategies, (v) governmental approvals and regulations, and (vi) our future business development, results of operations and financial condition. In some cases, forward-looking statements can be identified by words or phrases such as “may,” “will,” “expect,” “anticipate,” “target,” “aim,” “estimate,” “intend,” “plan,” “believe,” “potential,” “continue,” “is/are likely to” or other similar expressions. All information provided in this press release is as of the date of this press release, and YY Group Holding Limited undertakes no duty to update such information, except as required under applicable law.

Investor Contact

Jason Phua Zhi Yong, Chief Financial Officer
YY Group
enquiries@yygroupholding.com

Former Cisco and Meraki executive to oversee Plume’s go-to-market strategy with a focus on deepening engagement with ISP customers and building subscriber confidence by turning intelligence into action

PALO ALTO, Calif., Jan. 21, 2026 /PRNewswire/ — Plume, a leader in cloud-managed Wi-Fi, security, and smart home services for Internet Service Providers (ISPs), today announced the appointment of Rebecca Stone as the company’s new Chief Marketing Officer.

Plume Appoints Rebecca Stone as Chief Marketing Officer

Stone brings more than 20 years of experience leading global enterprise and service provider marketing organizations across brand, product marketing, growth, and revenue strategy, as well as a deep understanding of service provider needs across multiple industry tiers. Most recently, she served as Senior Vice President of Revenue Marketing and Customer Solutions Marketing at Cisco, where she oversaw media, integrated marketing, campaign planning, content marketing and operations, and demand marketing for Cisco’s $50B networking portfolio.

At Plume, Stone will help Plume deepen engagement with ISP customers while clearly articulating the value of the company’s expanding capabilities around intelligent Wi-Fi management, telemetry and analytics, cybersecurity, and customer care, powered by an unprecedented dataset and artificial intelligence. Plume aims to work with ISPs to strengthen subscriber confidence by turning data and insights into action, including a more robust offering that incorporates powerful AI orchestration technology from recently acquired Sweepr.

“The industry is shifting quickly, and Plume is entering a new chapter: one platform, a stronger customer experience, and more value from data and AI for ISPs,” said Dan Herscovici, CEO of Plume. “In a market this crowded, clarity wins and we’re going to make Plume the obvious choice. Rebecca has built and scaled world-class marketing teams across cloud, networking, and service providers. Her customer empathy and ability to translate complex technology into differentiated value will be critical as we help partners stand out, grow, and compete.”

Plume’s cloud platform connects nearly half a billion devices, creating an unmatched foundation of real-world network and device telemetry across diverse home environments. In this rapidly evolving broadband landscape—with rising subscriber expectations, intensifying competition, and AI shaping service delivery—Stone will oversee marketing strategy, brand positioning, and go-to-market execution as the company enters its next phase of growth. She will play an integral role in how Plume communicates this refreshed approach and suite of new capabilities to ISPs and the broadband industry, bringing them to life with clarity and inspiration across channels.

“I’m delighted to join Plume at this transformative moment in the company’s growth,” says Rebecca Stone, Chief Marketing Officer at Plume. “I’ve spent my career focused on building innovative marketing teams that accelerate growth and drive customer success, especially in an increasingly AI-powered landscape. There’s nothing more valuable than hearing from your customers, learning from them, and turning those insights into action that propels their success. I look forward to curating experiences where Plume can engage in a deeper and more meaningful way with them in the year ahead.”

Prior to Cisco, Stone was Chief Marketing Officer at Meraki, where she doubled the global marketing team to 150 employees, led a major rebrand and messaging transformation, and grew marketing-sourced pipeline contribution to 35%. At LiveRamp, she served as VP of Marketing, leading a team of 70 marketers and sales staff and helping the company expand from $20M to $300M+ in four years. She previously held marketing leadership roles at DataSift and Calix, and holds a Bachelor of Arts in Communications from UC Santa Barbara.

About Plume
Plume created the first managed Wi-Fi platform for Internet Service Providers (ISPs) in 2016 and continues to lead today with a best-in-class solution for cloud-managed Wi-Fi, security, and workflow orchestration – all powered by an unmatched dataset and AI. With almost half a billion devices connected to its platform, Plume is a trusted technology partner for more than 400 ISPs around the world, helping them deliver subscriber confidence through better Wi-Fi experiences, new services, and proactive customer care. Plume leverages OpenSync®, an open-source framework that comes pre-integrated and supported on the leading silicon, CPE, and platform SDKs, and supports leading industry standards like RDK-B and prplWave. Combined with powerful AI orchestration tools with its acquisition of Sweepr, Plume now offers ISPs a true end-to-end solution to power their most important workflows and customer experiences, while making deployment simpler and faster. Plume is leading the way in providing ISPs an intelligence and innovation edge to stay competitive, build subscriber confidence, and adapt to the changing needs of the market. Discover more about how Plume is empowering ISPs by visiting https://www.plume.com.

• TECNIMONT has signed a term sheet to participate as integrated engineering service provider in the development of Argent LNG’s groundbreaking 25 MTPA LNG project in Louisiana, United State

• TECNIMONT will leverage its proven ability to integrate advanced Original Equipment Manufacturers (OEM) technologies, across engineering, Federal Energy Regulatory Commission (FERC) permitting and Front-Engineering Design (FEED) development, for which contracts are expected to be finalized soon

• The collaboration represents a platform for innovation, linking Italian and American expertise to build resilient, scalable, and repeatable LNG infrastructures

MILAN, Jan. 21, 2026 /PRNewswire/ — MAIRE (Milan: MAIRE) announces that TECNIMONT S.p.A. has signed a term sheet with Argent LNG, LLC (“Argent LNG”), marking TECNIMONT’s strategic entry into the global LNG market. The term sheet lays the foundation for TECNIMONT’s participation in the development of the Argent LNG export facility project located in Port Fourchon, Louisiana – one of the most strategically hurricane-resilient energy hubs in the United States.

This strategic framework represents TECNIMONT’s first operational step into the LNG export segment, a business area identified among the growth drivers for MAIRE’s Integrated Engineering & Construction (IE&CS) business unit.

TECNIMONT and Argent LNG establish a long–term alignment across engineering and project development as the project advances through Federal Energy Regulatory Commission (FERC) permitting, Front–End Engineering Design (FEED), for which contracts are expected to be finalized soon, in order to support the final investment decision.

The Argent LNG and TECNIMONT modular platform is designed to be fully replicable, scalable, and financeable, enabling rapid and predictable responses to global LNG demand. Every module has been optimized for constructability, transportability, and integration with proven Original Equipment Manufacturers (OEM) technologies. The Argent LNG platform, in fact, has been engineered around modular solutions from globally recognized technology leaders. This integrated approach is intended to enhance execution certainty, reduce interface risk, and support a disciplined pathway to final investment decision.

The collaboration delivers a truly bankable and repeatable solution that can be deployed across multiple projects and geographies, establishing a new global standard for modular LNG infrastructure.

This achievement represents further evidence of TECNIMONT’s ability to deliver disciplined development, precise engineering execution, and integration of OEM technologies such as Baker Hughes.

Alessandro Bernini, Chief Executive Officer of MAIRE, commented: “We are extremely proud and excited to start this innovative project. This collaboration with Argent LNG not only strengthens our presence in the US but also opens to a new market for the Group, thanks to TECNIMONT’s recognized capabilities in the modularized approach and its flexibility to adapt to new challenging opportunities”

Jonathan Bass, Founder and Executive Chairman of Argent LNG, commented: “This term sheet represents a meaningful alignment between capital, engineering, and execution. Engaging a Tier-1 global engineering organization at this stage underscores the seriousness, discipline, and long-term vision behind the Argent LNG platform. Our objective is to build a project that meets the highest standards of technical excellence, regulatory credibility, and capital efficiency.”

MAIRE S.p.A. is a leading technology and engineering group focused on advancing the Energy Transition. We provide Integrated E&C Solutions for the downstream market and Sustainable Technology Solutions through three business lines: Sustainable Fertilizers & Nitrogen-Based Fuels, Low-Carbon Energy Vectors, and Circular Solutions. With operations across 50 countries, MAIRE employs approximately 10,500 people, supported by around 50,000 professionals involved in its projects worldwide. MAIRE is listed on the Milan Stock Exchange (ticker “MAIRE“). For further information: www.groupmaire.com.

MOMENCE, Ill., Jan. 21, 2026 /PRNewswire/ — New research published in Frontiers in Nutrition has revealed the significant impact of Organic NatureKnit®, an all-natural and patent-pending gut health innovation from FutureCeuticals, on the human gut microbiome.

The study, conducted in partnership with ProDigest, a leading microbiome research organization based in Ghent, Belgium, demonstrates that Organic NatureKnit exhibits significant prebiotic activity within the human gut microbiome. The research demonstrates that Organic NatureKnit induces significant and sustained metabolic activity and modulates the microbiome more comprehensively than commonly used purified organic fiber ingredients. Utilizing ProDigest’s validated and widely regarded M-SHIME model to simulate the human gastro-tract and microbial system, the effects of Organic NatureKnit on the active human microbiome were observed for the first time.

The results demonstrated that just 2.5 grams of Organic NatureKnit led to a slow, gentle fermentation profile, as well as a sustained, long-lasting prebiotic effect. Compared to popular organic purified fibers, Organic NatureKnit had a significantly greater prebiotic effect at 48 hours across measures of total abundance of healthy gut bacteria, bacterial species richness, and total short-chain fatty acids (SCFAs).

“Our NatureKnit portfolio represents an exciting fusion of our passion for creating natural, sustainable ingredients with state-of-the-art scientific research methods,” said Brendan Kesler, Innovation Director at FutureCeuticals and Postgraduate Researcher at The Rowett Institute. “This new research demonstrates that our patented blend of diverse fruit and vegetable fibers, along with naturally occurring fiber-bound polyphenols, delivers a greater and more sustained prebiotic effect compared to purified fibers within the human gut microbiome.”

“It’s an exciting development for the nutrition industry, because Organic NatureKnit goes beyond popular purified fibers to deliver several key attributes consumers are seeking in gut health products,” Kesler added. “It’s fully organic and sustainable, gentle, and offers a comprehensive microbiome benefit much broader than purified fibers.”

About FutureCeuticals, Inc.

FutureCeuticals, Inc. is the exclusive developer of NatureKnit® and a leader in the research, development, and manufacture of plant-based powders and extracts for the functional food, beverage, and dietary supplement markets.

SEOUL, South Korea, Jan. 21, 2026 /PRNewswire/ — Uncle Gurye, a premium food specialist based in South Korea, has announced the expansion of its Home Meal Replacement (HMR) lineup with the global launch of two new products: the Dried Herb Kit for Bibimbap and the Korean Savory Pancake Kit. Both products are crafted using pristine raw ingredients harvested from Korea’s most renowned natural highlands.

By working closely with local Korean farms through contract farming, Uncle Gurye ensures the highest quality of produce. This direct partnership reinforces product reliability and supports the sustainable growth of Korea’s agricultural communities.

Innovation in Convenience: No Soaking Required

The brand’s flagship product, the Dried Herb Kit for Bibimbap, is the result of a precision-controlled process of washing, blanching, and specialized drying. This innovative method allows the herbs to be used immediately, eliminating the long preparation times traditionally associated with dried Korean vegetables.

• Effortless Preparation: Unlike conventional dried vegetables that require hours of soaking, these herbs can be cooked directly with rice. This allows anyone to enjoy a healthy, authentic bowl of bibimbap with minimal effort.
• Premium Korean Ingredients: The kit features carefully selected herbs such as Ssukbujaengi (Aster yomena), known for its unique aroma and health benefits, ensuring a deep and rich flavor for your bibimbap.
• Nutrient Retention: The specialized processing method minimizes nutrient loss, enabling health-conscious consumers to enjoy a nutrient-dense, traditional bibimbap even with a busy modern lifestyle.

Authentic Flavors Made Easy: Korean Savory Pancake Kit

The newly released Korean Savory Pancake Kit (Buchimgae) is designed to bring the quintessential taste of Korean soul food to kitchens around the world.

• Balanced Formulation: This pancake kit features an optimal blend of premium Korean herbs and high-quality pancake mix, ensuring a consistent flavor and a perfect crispy texture every time.
• Just Add Water: Preparing a delicious meal is simpler than ever; users only need to add water to the pancake kit. This convenience makes it an ideal choice for quick home meals or outdoor activities such as camping.
• Versatile Applications: The pancake kit serves as a perfect solution for those wanting to experience authentic Korean cuisine or for families looking for a healthy, vegetable-rich snack.

Commitment to Honest Food and Global Quality

Uncle Gurye adheres to strict hygiene standards and avoids chemical additives to preserve the natural, earthy taste of its ingredients. The company is dedicated to sharing the true value of Korean food culture through a transparent distribution network that connects Korean producers directly with global consumers.

“These products were developed to deliver the richness of Korea’s natural herbs in the most convenient form,” said a representative from Uncle Gurye. “Whether through our bibimbap kit or our pancake kit, we aim to provide honest, high-quality food that people everywhere can trust and enjoy.”

Uncle Gurye’s products are currently available through its official online store. The company plans to continue its research and development to further expand its lineup of herb-based HMR and Korean fusion food products.

▶ Official Website: http://www.guryeuncle.com/en/product