TAIPEI and SAN DIEGO, Dec. 23, 2025 /PRNewswire/ — Senhwa Biosciences, Inc. (TPEx: 6492), a clinical stage companies focusing on development of first-in-class therapeutics for oncology, rare diseases, and infectious diseases, today outlined continued progress across its AI-enabled drug development platform at its 2025 annual investor conference, reinforcing its strategic position as the global immuno-oncology landscape enters a period of generational transition.

Global blockbuster immune-oncology products now face major patent expirations before 2030 pharmaceutical companies are either actively developing or acquiring next-generation assets that are highly combinable, scalable across multiple tumor types with potential of becoming treatment standard in different types of cancers. Senhwa is addressing this demand through an integrated strategy that combines artificial intelligence validation, precision clinical development, and global pharmaceutical partnerships.

Recently, Google DeepMind applied its latest C2S-Scale biological AI model to analyze more than 4,000 drug candidates and identified Senhwa’s lead compound Silmitasertib (CX-4945) as the most potential compound to revigorate immune system to combat with cancer. The study, supported by Google’s computing infrastructure, DeepMind’s proprietary AI models, and preclinical validation conducted by Yale University, demonstrated that CX-4945 significantly enhances tumor antigen presentation—an essential mechanism for improving immune recognition of cancer cells.

This independent third-party validation highlights the potential of CX-4945 as an immune-sensitizing agent and represents a notable milestone in the application of AI to oncology drug discovery. By addressing the long-standing challenge of immunologically “cold” tumors, which had limited response to immunotherapy, CX-4945 has a unique position in the rapidly expanding field of cold-to-hot tumor conversion.

In parallel, Senhwa continues to advance its clinical pipeline through strategic international collaboration. The company recently announced a clinical collaboration with BeOne Medicines to evaluate Senhwa’s lead candidate, Pidnarulex (CX-5461), in combination with BeOne’s commercially approved, best-in-class PD-1 inhibitor tislelizumab. The initial focus of the collaboration includes pancreatic cancer and advanced solid tumors, including immunotherapy-resistant melanoma.

CX-5461 is a first-in-class small molecule with a differentiated dual mechanism of action that stabilizes DNA G-quadruplex (G4) structures while inhibiting RNA polymerase I (Pol I). This dual activity induces replication stress in tumor cells and activates the innate immune cGAS–STING pathway, effectively converting immune-cold tumors into immune-active environments. Robust preclinical data supports the application of CX-5461 in enhancing the efficacy of existing immunotherapies and becoming the ideal candidate for combination therapy with immune-oncology products.

Senhwa believes this pathway-level, multi-target strategic approach positions CX-5461 as a potential next-generation treatment back bone in cancers where immunotherapy is used, rather than positioning the compound as a single-asset or indication-specific solution. This strategic positioning has attracted interest from global pharmaceutical companies seeking high value added platform assets, as reflected by ongoing and prior collaborations involving leading multinational partners.

Looking ahead, Senhwa expects multiple value-driving catalysts over the next one to three years, including clinical data readouts for CX-5461 and CX-4945, expansion of global partnerships, potential licensing collaborations, and increased visibility at major international medical conferences such as ASCO, AACR, and ESMO.

“Senhwa has transitioned beyond early-stage discovery and development into a company building a scalable, AI-validated oncology platform,” said the Company. “At a pivotal moment for immuno-oncology, we are focused on advancing differentiated science with the potential to create long-term value for patients, partners, and shareholders.”

NEW YORK, Dec. 23, 2025 /PRNewswire/ — The latest winners of the MUSE Design Awards have just been announced, and Skydream — a global innovator in the RV industry — has stood out from the competition. Its next-gen new-energy smart travel trailer for off-grid travel, Space Camping, has been honored with the Platinum Award, the highest recognition of the program.

Established in 2015 by the International Awards Associate (IAA) in the United States, the MUSE Design Awards are renowned for their rigorous evaluation system and high standards of excellence. Today, they are recognized as one of the most prestigious and influential honors in the global design industry. Divided into three levels — Platinum, Gold, and Silver — the MUSE Design Awards honor excellence and innovation across the fields of creative design, advertising, and digital media worldwide. Space Camping’s Platinum Award signifies a resounding affirmation from global design authorities of its aesthetic vision and innovative excellence.

Design Vision: Redefining Freedom in Mobile Living

Despite being a massive, trillion-dollar global industry, the RV sector has been slow to adopt electrification and intelligent technologies, with limited product innovation overall. These challenges — ranging from energy dependence to complex operations — significantly limit the freedom of mobile living for users. Meanwhile, RV design has long been trapped in a rigid visual language, with countless models still echoing the outdated “white box” form — failing to resonate with today’s pursuit of personal expression and emotional freedom.

Freedom, in its truest form, transcends convention — it mirrors the infinite expanse of the universe. Guided by this vision, Skydream introduced its pioneering design philosophy: Interstellar Camping. The design team fused the rational order and technological aesthetics of spacecraft with the human warmth essential to mobile living — breaking through the formal and experiential boundaries of traditional RVs to create a mobile space that embodies both futuristic vision and the spirit of freedom.

Was it the space camping aesthetic that captivated the MUSE judges?

With flowing contours and a luminous pearl-white finish, Space Camping channels the elegance of spacecraft into a vision of the future. The lighting system reinforces the narrative theme: a continuous strip of cool white light and indicator lamps shift to a tranquil blue in smart mode, echoing the technological aura of space exploration. The taillights, crafted with an ice-crystal-like transparency, subtly reference the extreme cold and vacuum of outer space — deepening the storytelling embedded in the Space Camping design.

Echoing the space-travel aesthetic of its exterior design, the interior adopts a tri-color scheme, where white evokes the tangible form of the RV, black reflects the infinite expanse of space, and silver captures the motion of starlight. The main furnishings, ceiling light panels, and kitchen volumes appear to float within a cosmic void. Paired with dynamic lighting and shadows, they evoke a sense of spatial levitation — expressing the tension in postmodern design.

The next-gen RV: a complete reinvention of nomadic living

As a new species of RV envisioned for future nomadic life, Space Camping doesn’t stop at design. It redefines the journey with advanced energy systems and intelligent technologies that transform how we live on the move. Equipped with a high-efficiency solar charging system and a large-capacity battery pack, the ERV supports up to 14 days of off-grid living. As a self-powered travel trailer, its advanced all-scenario intelligent driving assistance system integrates driving support, automatic parking, and one-touch trailer hitching — greatly enhancing safety and ease of use. It also features the world-leading full-vehicle intelligent control system for RVs, enabling multimodal interaction through voice commands, mobile apps, and integrated control panels. This allows for seamless human-vehicle interaction and scenario-based smart management — freeing users’ hands and delivering a truly effortless, harmonious travel experience.

Skydream Space Camping is more than just an electric travel trailer — it is a mobile living vehicle that fuses space aesthetics, intelligent technology, and sustainable energy. It embodies Skydream’s groundbreaking exploration in the field of RV design. Building on this prototype, Skydream will launch a new-generation production model of its new-energy smart travel trailer next year. Set to debut in North America, it promises a mobile living experience defined by freedom, comfort, and imagination.

Discover More in Skydream:

https://www.youtube.com/watch?v=3h9s3rZA7Lc

HONG KONG, Dec. 23, 2025 /PRNewswire/ — NetDragon Websoft Holdings Limited (“NetDragon” or “the Company”; Hong Kong Stock Code: 777), a global leader in building internet communities, is pleased to announce that it plans to invest in the AI-driven, globally co-created and shared, decentralized educational ecosystem Open Quest Academy (“Open-Q”), in return will receive utility token – Q101.

The Open-Q ecosystem made its debut during the Digital Learning Week, held by UNESCO in early September this year at its headquarters in Paris. It has attracted extensive attention from senior UNESCO officials, education ministers from more than 30 countries, as well as experts, scholars, seasoned educators, and educational content creators. Aligned with the global consensus on reimagining the future of learning, Open-Q is committed to building a next-generation educational ecosystem that promotes equity, technology empowerment, and global collaboration. Open-Q brings together experts, teachers, and practitioners to collaborate on metaverse-based learning and teaching platforms. The ecosystem is anchored in three core principles: technology for equity, co-creation of resources, and incentive-driven participation.

Open-Q’s mission of global education equity highly aligns with UNESCO’s policy goals, as it offers open, high-quality digital learning resources that can be localized and adapted to the curriculum needs of specific regions. This approach helps promote global education equity and quality improvement, positioning Open-Q as a transformative open platform for teaching and learning in the digital era. Open-Q also aims to achieve shared governance among global users by building a decentralized and vibrant “Learn-and-Earn” community to incentivize and reward learners worldwide. By combining economic incentives with competency-based learning, it creates a virtuous cycle in which learners acquire market-relevant skills, educators receive recognition and compensation for creating high-quality content, and the entire community benefits from a continuously expanding shared knowledge base.

NetDragon has been deeply engaged in the online education business since the early 2010s, accumulating extensive technology know-how, resources, and experiences across areas such as digital textbooks, AI-powered courseware, virtual experiments, classroom SaaS solutions, interactive educational games, and more importantly, the development and operation of national-level AI education platforms that integrate the above-mentioned resources. Since 2025, NetDragon has further upgraded its strategy into “AI + Education”, enabling highly efficient production of high-quality AIGC educational content through its self-developed AI Content Factory. In the future, there is significant potential for strategic synergies between Open-Q and NetDragon, and the proposed investment of Q101 token will further diversify the Company’s digital asset portfolio, with the potential to create significant value for shareholders.

TORTOLA, British Virgin Islands, Dec. 23, 2025 /PRNewswire/ — Worldwide Stablecoin Payment Network (WSPN), a leading provider of next-generation stablecoin infrastructure, today announced a strategic partnership with TradeGo, a digital service platform specializing in global commodity trade documentation. The collaboration aims to digitize commodity documentation and cross-border settlements, modernizing supply chains and reshaping trade finance across Australia, Asia, and Latin America. The partnership integrates WSPN’s stablecoin settlement technology with TradeGo’s blockchain-based electronic Bill of Lading (eBL) infrastructure, enabling businesses to access faster, more transparent, and cost-effective global trade operations.

Closing the Digital Loop with Stablecoin Settlements

As global trade increasingly demands greater speed and transparency, stablecoins are emerging as critical infrastructure for cross-border settlements. WSPN’s stablecoin technology addresses the fundamental challenge of traditional banking rails: slow, geographically constrained, and dependent on multiple intermediaries. When combined with TradeGo’s blockchain-based eBL, which provides cryptographic security and real-time verification, the solution eliminates both documentation fraud and settlement delays.

WSPN’s USD-based stablecoin completes the digital loop by enabling instant settlement once documents and title transfers are validated on-chain. The technology removes time-zone delays, correspondent banking friction, and multi-day clearing cycles that constrain traditional payment systems.

The joint solution synchronizes cargo title transfers with stablecoin payments. When a shipment is verified and title is transferred on TradeGo’s platform, payment is released instantly via WSPN’s infrastructure. This turns a multi-day process into an immediate transaction, reducing credit risks, minimizing trade fraud, and accelerating liquidity for all parties involved.

Reshaping Trade Finance for the Digital Economy

The integration of WSPN’s stablecoin settlements reshapes how trade finance operates. Lenders gain real-time visibility into supply chain data and reduce fraud risks. Borrowers, particularly SMEs and mid-market exporters, access faster liquidity and more inclusive financing options outside traditional banking channels.

This is especially impactful for high-growth trade corridors including Australia-Southeast Asia (agriculture, minerals, metals), China-LATAM (energy products, industrial commodities), and ASEAN-Australia-LATAM (diversified commodities and manufacturing inputs).

This partnership marks a significant step in bringing global commodity trade on-chain, enabling businesses to settle transactions at blockchain speed with full transparency and regulatory compliance.

About WSPN

WSPN is a leading provider of next-generation stablecoin infrastructure, dedicated to building a more secure, efficient, and transparent global payment ecosystem. Our flagship stablecoin, WUSD, is fully backed and pegged 1:1 to the U.S. Dollar, serving as the foundation for a suite of integrated financial solutions. These solutions support a range of financial applications from institutional treasury management to programmable payments and decentralized finance. With a strong focus on transparency, regulatory compliance, and user accessibility, WSPN bridges the gap between Web3 innovation and traditional financial systems, driving the global adoption of stablecoins at scale.

Learn more: www.wspn.io | X | LinkedIn

About TradeGo

Founded in Singapore in November 2021, TradeGo is backed by major industry players including Sinochem, PetroChina, Macquarie, COSCO Shipping Energy, China Merchants Energy Shipping, Saudi Aramco, Mitsui, Bank of China, China Construction Bank, and Wanxiang Blockchain. TradeGo leverages blockchain technology to ensure transaction security, efficiency, and privacy in the transmission of trade documents. For more information, visit: https://www.tradego.com/