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HanchorBio Announces Oral Presentation of HCB101 at the ESMO Immuno-Oncology Congress 2025

International debut underscores emerging role for macrophage checkpoint therapy in gastric cancer, triple-negative breast cancer, and other hard-to-treat solid tumors

TAIPEI, SHANGHAI, AND SAN FRANCISCO, Dec. 11, 2025 /PRNewswire/ — HanchorBio Inc. (TPEx: 7827), a global clinical-stage biotechnology company advancing next-generation immunotherapies for oncology and autoimmune diseases, today announced that new clinical data from its flagship macrophage-checkpoint program, HCB101, has been selected for a mini oral presentation at the ESMO Immuno-Oncology Congress 2025 in London, United Kingdom. Only 26 abstracts were chosen for mini-oral presentation this year, marking a major milestone for HanchorBio as it delivers its first-ever oral presentation of clinical data at an international oncology congress, following its prior preclinical oral presentation of HCB101 at CSCO 2022.

HanchorBio Announces Oral Presentation of HCB101 at the ESMO Immuno-Oncology Congress 2025
HanchorBio Announces Oral Presentation of HCB101 at the ESMO Immuno-Oncology Congress 2025

The ESMO Immuno-Oncology Congress is Europe’s premier meeting dedicated exclusively to immuno-oncology science, distinct from the broader ESMO Annual Congress. While the annual ESMO meeting spans all oncology disciplines, ESMO-IO focuses on immune mechanisms, translational innovation, and next-generation therapeutic strategies across innate and adaptive immunity.

Presentation Details:

Abstract ID: 242MO
Title: HCB101, a Differentiated SIRPα Fusion Protein, Demonstrates Favorable Safety and Early Antitumor Activity Across Solid Tumors and Lymphoma
First Author: Dr. Fangling Ning, Affiliated Hospital of Binzhou Medical University
Date / Time: 11 December 2025 / 11:45 – 12:45 GMT
Location: Whittle Room, Queen Elizabeth II Centre, London
Presenter: Alvin Luk, PhD, MBA, CCRA – President & CMO (Group) and CEO (U.S.A.), TIME100 Health 2025 Honoree

“For nearly a decade, CD47 therapies were held back not by flawed biology but by flawed molecules, which struggled to balance safety and efficacy at the same time, especially in immunologically cold tumors,” said Scott Liu, PhD, Founder, Chairman, and CEO of HanchorBio. “HCB101 was engineered from the ground up to solve that problem. Using AI-guided structural modeling, we identified three core mutations that reshape SIRPα’s interaction with CD47, allowing us to combine the strengths of first- and second-generation approaches into a single, differentiated molecule. Being selected as one of only 26 mini-oral presentations at ESMO Immuno-Oncology reinforces the field’s recognition of this effort and redefines the CD47 therapies. With its clean safety profile, strong target engagement, and early activity in cold tumors, HCB101 is emerging as a true macrophage-checkpoint backbone – much like the transformative PD-1/PD-L1 therapies that were based on T-cell checkpoint inhibition.”

Key Findings Highlighted in the Mini-Oral

Monotherapy (HCB101-101; NCT05892718)

  • Clean, cytopenia-sparing safety across 12 cohorts up to 36 mg/kg QW
  • No bleeding events or immune-related toxicities, with the majority of treatment-related adverse events being Grade 1-2
  • Linear PK (T1/2 ~3 days) with receptor occupancy (RO) >99% at ≥8 mg/kg
  • Durable antitumor activity, including confirmed PRs in:
    • HNSCC -Head and neck squamous cell carcinoma (~42% tumor regression, ≥32 weeks)
    • MZL – Marginal zone lymphoma (~89% tumor regression, ≥16 weeks)
  • Stable disease ≥4-9 months across colorectal cancer (CRC), ovarian cancer, non-small cell lung cancer (NSCLC), and sarcoma
  • Combination Therapy (HCB101-201; NCT06771622)
  • Well-tolerated across gastric cancer (GC), triple-negative breast cancer (TNBC), CRC, and HNSCC
  • No new safety signals across all evaluated combinations
  • Cytopenias fully attributable to chemotherapy, not HCB101
  • 2L GC:
    • 58.3% ORR (7/12) for all cohorts evaluated, 77.8% ORR (7/9) for mid-dose cohorts, and 100% DCR
    • Tumor shrinkage up to -78.2%
  • 1L HER2+ GC: 33% ORR (1/3)
  • 1L TNBC: 50% ORR (3/6) and 100% DCR

Alvin Luk, PhD, MBA, CCRA, President & Chief Medical Officer (Group) and Chief Executive Officer (U.S.A.) of HanchorBio, added, “The early efficacy signals from HCB101 are unusually compelling for this stage of development. In second-line GC, where standard therapy achieves an ORR of about 27%, HCB101 combinations exceed 78% ORR, achieve 100% disease control, and result in tumor reduction approaching -78%. These results are not incremental; they meaningfully exceed expectations and reflect robust macrophage checkpoint engagement. With clean safety and sustained receptor occupancy, the data give us confidence to anchor development in second-line disease and expand into first-line and perioperative settings where depth and durability of response matter most.”

About HCB101: A Next-Generation SIRPα Fc-Fusion Protein

HCB101 is a 3.5th-generation engineered SIRPα-Fc fusion protein with an intact IgG4 Fc backbone, developed using HanchorBio’s FBDB™ platform to selectively target tumor CD47 while minimizing binding to red blood cells. This design avoids the anemia and thrombocytopenia that limited early anti-CD47 programs, while preserving potent macrophage activation and downstream T-cell engagement. Key differentiators include:

  • Cytopenia-sparing safety up to 30-36 mg/kg
  • Receptor occupancy (RO) >99% at clinically active exposures
  • Strong macrophage and downstream T-cell activation
  • Broad antitumor activity across >80 PDX/CDX models and multiple clinical tumor types
  • Robust early combination efficacy in tumors that historically respond poorly to immunotherapy

Unlike earlier approaches, HCB101’s safety, target selectivity, and RO profile support its use as a macrophage-checkpoint backbone – analogous to how PD-1/PD-L1 inhibitors function as foundational T-cell backbones in oncology. HCB101 is designed for broad combinability across established and emerging treatment modalities, including:

  • Chemotherapy
  • Antibody-drug conjugates (ADCs)
  • Anti-PD-1/anti-PD-L1 checkpoint inhibitors
  • Anti-VEGF inhibitors
  • Anti-EGFR therapies
  • Anti-HER2 regimens

This versatility positions HCB101 as a modular, next-generational immuno-oncology component capable of enhancing the efficacy of multiple therapeutic backbones across solid tumors and hematologic malignancies.

About HanchorBio

Based in Taipei, Shanghai, and the San Francisco Bay Area, HanchorBio (TPEx: 7827) is a global biotechnology company specializing in immuno-oncology. It is led by an experienced team of pharmaceutical industry veterans with a proven track record in biologics discovery and international development, aiming to rewrite the landscape of cancer therapies. Committed to reactivating the immune system to fight diseases, the proprietary Fc-based designer biologics (FBDB™) platform enables the development of unique biologics with diverse multi-targeting modalities, unleashing both innate and adaptive immunity to overcome the current challenges of anti-PD1/L1 therapies. The FBDB™ platform has successfully delivered proof-of-concept data in several in vivo tumor animal models. By advancing breakthroughs in multi-functional, innovative molecular configurations in R&D and improving CMC manufacturing processes, HanchorBio develops transformative medicines to address unmet medical needs. For more information, please visit: https://www.hanchorbio.com/

O-RAN Global PlugFest Fall 2025 Showcased Continued Evolution of Advanced Use Cases and Scenarios Featuring AI in the RAN

  • O-RAN ALLIANCE PlugFests offer collaborative environment to accelerate the development of open and intelligent RAN-based solutions
  • The O-RAN Global PlugFest Fall 2025 showcased advances in automation, network optimization, energy efficiency, and security – many featuring AI in the RAN
  • The Fall 2025 PlugFest was co-hosted by 25 operators, OTICs and institutions in 19 labs worldwide – with a total of 64 companies and institutions participating

BONN, Germany, Dec. 11, 2025 /PRNewswire/ — The O-RAN ALLIANCE (O-RAN) today announced successful completion of the O-RAN Global PlugFest Fall 2025.

O-RAN PlugFests are designed to accelerate the development of O-RAN based products and solutions by offering structured testing and integration opportunities in a neutral and collaborative environment.

Building on the momentum of previous PlugFests, the Fall 2025 event showcased continued evolution of open, intelligent, virtualized and interoperable Radio Access Network (RAN) solutions – with advances in automation, end-to-end integration of multi-vendor solutions, network optimization, energy efficiency, security, and more.

The Fall 2025 PlugFest showcased O-RAN performance in advanced scenarios like autonomous network operation agent, Distributed Antenna Systems (DAS) and O-RAN deployment for high-speed trains. Proofs of concept were conducted on compact GenAI models for O-RAN testing. Several scenarios were tested in live networks, and some are already being adopted in commercial operation.

O-RAN Global PlugFest Fall 2025 was hosted by 25 operators, Open Testing and Integration Centres (OTICs) and independent institutions in 19 labs worldwide. It was conducted from August to November 2025 with a total of 64 companies that took part, some of which involved in multiple venues.

“Our regular PlugFests provide incentives to diverse companies and institutions in the RAN industry to mature innovative O-RAN based solutions,” said Chih-Lin I, Co-chair of O-RAN ALLIANCE’s Technical Steering Committee and China Mobile Chief Scientist, Wireless Technologies, China Mobile Research Institute. “We are pleased to see demonstrations of readiness of many multi-vendor O-RAN deployments, and also advanced use cases and scenarios featuring AI in the RAN. A big thank you to all hosts, labs and participants for their great efforts and achievements.”

Participants in O-RAN ALLIANCE Global PlugFest Fall 2025

O-RAN ALLIANCE appreciates high interest from the community in testing and integration at the O-RAN Global PlugFest Fall 2025 and would like to recognize hosts, labs and participants, including:

1Finity, Accuver, Airhop Communications, AmpliTech Group, ANDREW – an Amphenol Company, AT&T, Calnex Solutions, DeepSig, Dell Technologies, Deutsche Telekom, Digital Catapult, EANTC, Eridan Communications, ETRI, EURECOM, G Reigns, Gigalane, HCL Technologies, HFR, HPE, i14y Lab, Intel, Iowa State University (ARA), IS-Wireless, Industrial Technology Research Institute (ITRI), KDDI, Keysight Technologies, Korea Telecom, Kumoh National Institute of Technology, LG Electronics, LG Uplus, LIONS Technology, LITE-ON Technology, NEC, Nokia, North Carolina State University (AERPAW), Northeastern University, NTT DOCOMO, Orange, Pegatron, Quanta Cloud Technology (QCT), Rakuten Mobile, Rakuten Symphony, Red Hat, Rohde & Schwarz, Rutgers University (COSMOS/WINLAB), Samji Electronics, Singapore University of Technology and Design (SUTD), SK Telecom, SoftBank, Software Radio Systems, SOLiD, Super Micro, TIM, TTA, University of New Hampshire Interoperability Labs (UNH-IOL), University of Utah (POWDER), Verizon, VIAVI Solutions, Vodafone, VVDN Technologies, Wave Electronics, Wind River, YRP R&D Promotion Committee.

About O-RAN ALLIANCE
The O-RAN ALLIANCE is a world-wide community of mobile operators, vendors, and research & academic institutions operating in the Radio Access Network (RAN) industry. As the RAN is an essential part of any mobile network, the O-RAN ALLIANCE’s mission is to re-shape the industry towards more intelligent, open, virtualized and fully interoperable mobile networks. The new O-RAN specifications enable a more competitive and vibrant RAN supplier ecosystem with faster innovation to improve user experience. O-RAN based mobile networks at the same time improve the efficiency of RAN deployments as well as operations by mobile operators. To achieve this, the O-RAN ALLIANCE publishes new RAN specifications, releases open software for the RAN, and supports its members in integration and testing of their implementations.
For more information, please visit www.o-ran.org.

O-RAN ALLIANCE PlugFest
O-RAN ALLIANCE PlugFest

 

MATELASER W1 REGEN: The Lightest 24g and Highest 5,100 mW/cm² Wearable Red Light Therapy Device Debuts on Kickstarter

MIAMI, Dec. 11, 2025 /PRNewswire/ — MATELASER, INC., a pioneer in mobile laser therapy, today announced the official launch of its global crowdfunding campaign for the W1 REGEN, a breakthrough device that brings clinic-grade laser therapy into an ultra-miniature 24g wearable form. Priced at just $99, W1 REGEN officially breaks the cost barrier for true medical-grade photobiomodulation, marking a major step forward in the consumerization of laser therapy.

A New Category: Pocket-Sized, Deep-Tissue Laser Therapy

Unlike large LED-panel “red light masks” and low-irradiance consumer gadgets, the W1 REGEN delivers 5100 mW/cm² via dual-wavelength VCSEL architecture (US patent pending), engineered for muscle, tendon, joint and bone-level penetration.

Wavelength

Tissue Target

Clinical Role

660 nm

Skin & capillary beds

Microcirculation, surface repair

810 nm

Deep muscle, fascia, periosteum

Gold-standard wavelength for functional recovery

Early Validation at Bryan Johnson’s “Don’t Die Summit”

On December 7, just days before its official Kickstarter launch, the W1 REGEN debuted at Bryan Johnson’s “Don’t Die Summit,” drawing intense interest from bio-optimization leaders, longevity researchers, and elite recovery specialists. Attendees expressed immediate purchasing intent, reinforcing the device’s emergence as a credible tool in evidence-driven performance medicine.

MATELASER W1 REGEN
MATELASER W1 REGEN

Who It Helps — and Why It Matters

The W1 REGEN was engineered for users who need real therapeutic depth, not cosmetic glow:

  • Endurance athletes & marathon runners
  • Chronic lower-back & cervical tension sufferers
  • Post-surgical tissue healing
  • Tendinitis, tennis elbow, runner’s knee
  • Office-based inflammation & scapular tightness
  • Aging-related joint discomfort & microvascular decline

From recovery labs to living rooms, deep-penetration laser therapy is now portable.

Experience the W1 REGEN at CES 2026

Building on momentum from the Summit and Kickstarter activation, MATELASER will showcase the full Unbound wearable recovery ecosystem at CES.

Date: January 6-9, 2026
Location: Venetian Expo, Halls A-D
Booth: 56549

Kickstarter Campaign Details

The W1 REGEN is now live on Kickstarter. Backers can secure early bird pricing and become the first users to join MATELASER’s “Unbound” pain management ecosystem.

To learn more or support the campaign, Kickstarter: Search ‘W1 REGEN’

About MATELASER, INC.

Headquartered in Miami, MATELASER, INC. is an FDA-certified manufacturer specializing in mobile and professional laser therapy systems. With decades of leadership in photobiomodulation engineering, the company is committed to making clinically effective laser therapy safe, accessible, and affordable for everyday users worldwide.

Temu’s Brand Guardian Initiative Tops 1,500 Partners, Boosting Trademark Protection and IP Enforcement

Online marketplace now works directly with more than 1,500 brands to strengthen IP protection on and off its platform

BOSTON, Dec. 11, 2025 /PRNewswire/ — Temu, the global online marketplace, now works directly with more than 1,500 brands through its Brand Guardian Initiative, launched in April 2024 to provide stronger protection for intellectual property rights.

The program builds on Temu’s wider efforts to fight counterfeits and misuse of brands. It offers hands-on support, brand protection tools, and clear reporting, whether or not the brand sells on Temu.

Key features of the program include:

  • Protection for brands even if they don’t sell on Temu
  • Trademark and other IP rights embedding into the protection system for quicker spotting and removal of suspected violations
  • One-on-one support through tutorials, takedown help, and handling of complex IP cases
  • Regular insight reports to keep brands informed and improve results

“The Brand Guardian Initiative helps us create a safer, more trustworthy shopping experience,” said a Temu spokesperson. “We work with brands to protect their IP both on and off our platform and appreciate the collaboration that raises standards for online brand protection.”

Temu plans to expand the program further, adding more resources and strengthening enforcement.

Other brand protection measures and resources at Temu include:

  • Notice and Takedown portals covering various types of IP issues
  • 24/7 monitoring powered by proprietary algorithms and expert review
  • An in-house team that handles requests promptly
  • Seller education courses focusing on IP-related knowledge

Temu currently conducts proactive monitoring for over 5,000 brands and resolves more than 99% of takedown requests within three business days, with an average turnaround of less than 24 hours. Its proprietary proactive monitoring database has incorporated over 5 million images and 9 million keywords.

In addition, Temu works with global IP organizations and takes part in industry forums to share best practices and improve enforcement worldwide.

About Temu: 
Temu is a global e-commerce platform connecting consumers with millions of manufacturers, brands and business partners. Operating in more than 90 markets worldwide, Temu is committed to providing affordable, high-quality products that enable customers to live better lives.

Temu’s Brand Guardian Initiative Tops 1,500 Partners, Boosting Trademark Protection and IP Enforcement

Online marketplace now works directly with more than 1,500 brands to strengthen IP protection on and off its platform

BOSTON, Dec. 11, 2025 /PRNewswire/ — Temu, the global online marketplace, now works directly with more than 1,500 brands through its Brand Guardian Initiative, launched in April 2024 to provide stronger protection for intellectual property rights.

The program builds on Temu’s wider efforts to fight counterfeits and misuse of brands. It offers hands-on support, brand protection tools, and clear reporting, whether or not the brand sells on Temu.

Key features of the program include:

  • Protection for brands even if they don’t sell on Temu
  • Trademark and other IP rights embedding into the protection system for quicker spotting and removal of suspected violations
  • One-on-one support through tutorials, takedown help, and handling of complex IP cases
  • Regular insight reports to keep brands informed and improve results

“The Brand Guardian Initiative helps us create a safer, more trustworthy shopping experience,” said a Temu spokesperson. “We work with brands to protect their IP both on and off our platform and appreciate the collaboration that raises standards for online brand protection.”

Temu plans to expand the program further, adding more resources and strengthening enforcement.

Other brand protection measures and resources at Temu include:

  • Notice and Takedown portals covering various types of IP issues
  • 24/7 monitoring powered by proprietary algorithms and expert review
  • An in-house team that handles requests promptly
  • Seller education courses focusing on IP-related knowledge

Temu currently conducts proactive monitoring for over 5,000 brands and resolves more than 99% of takedown requests within three business days, with an average turnaround of less than 24 hours. Its proprietary proactive monitoring database has incorporated over 5 million images and 9 million keywords.

In addition, Temu works with global IP organizations and takes part in industry forums to share best practices and improve enforcement worldwide.

About Temu: 
Temu is a global e-commerce platform connecting consumers with millions of manufacturers, brands and business partners. Operating in more than 90 markets worldwide, Temu is committed to providing affordable, high-quality products that enable customers to live better lives.

China Matters’ Feature: Global Creators Unveil Yichun’s Allure

YICHUN, China, Dec. 11, 2025 /PRNewswire/ — A group of five influencers and four young creators from around the world recently journeyed to central China’s Yichun city, sharing its unique charm globally.


China Matters’ Feature: Global Creators Unveil Yichun’s Allure

They kicked off with traditional Chinese wellness, trying acupuncture and cupping. The gentle insertion of needles and the soothing suction left them fascinated by ancient healing arts.

At a pottery studio, they got hands – on, shaping clay into beautiful pieces, connecting with Yichun’s artistic heritage. They also delved into local culture, playing the lively Desheng Drum and being mesmerized by the mysterious Nuo Dance, while a fireworks factory tour set the stage for a nighttime spectacle. In Wanzai, a dazzling fireworks show lit up the sky, blending tradition with modern entertainment.

The next day, climbing Mingyue Mountain, they were greeted by a breathtaking sea of clouds at the summit. This awe – inspiring sight marked a perfect end to their adventure.

All the real experience the influencers had would be presented in their videos that’ll take the world on a virtual tour of Yichun’s wonders, fostering global appreciation for this Chinese gem.

YouTube Link:https://www.youtube.com/watch?v=qraTf-zOBHU

China Matters’ Feature: Global Creators Unveil Yichun’s Allure

YICHUN, China, Dec. 11, 2025 /PRNewswire/ — A group of five influencers and four young creators from around the world recently journeyed to central China’s Yichun city, sharing its unique charm globally.


China Matters’ Feature: Global Creators Unveil Yichun’s Allure

They kicked off with traditional Chinese wellness, trying acupuncture and cupping. The gentle insertion of needles and the soothing suction left them fascinated by ancient healing arts.

At a pottery studio, they got hands – on, shaping clay into beautiful pieces, connecting with Yichun’s artistic heritage. They also delved into local culture, playing the lively Desheng Drum and being mesmerized by the mysterious Nuo Dance, while a fireworks factory tour set the stage for a nighttime spectacle. In Wanzai, a dazzling fireworks show lit up the sky, blending tradition with modern entertainment.

The next day, climbing Mingyue Mountain, they were greeted by a breathtaking sea of clouds at the summit. This awe – inspiring sight marked a perfect end to their adventure.

All the real experience the influencers had would be presented in their videos that’ll take the world on a virtual tour of Yichun’s wonders, fostering global appreciation for this Chinese gem.

YouTube Link:https://www.youtube.com/watch?v=qraTf-zOBHU

“No Limits” 2026: A Celebration of Inclusion and Creativity All of Us, All Ways

11 Extraordinary Programmes Featuring Differently-Abled Local and International Artists Tickets Now Available at URBTIX


HONG KONG SAR – Media OutReach Newswire – 11 December 2025 – The eighth edition of “No Limits”, co-presented by the Hong Kong Arts Festival (HKAF) and The Hong Kong Jockey Club Charities Trust, will open on 27 February 2026 (Friday), under the theme “All of Us, All Ways”. This year’s programme invites audiences to reimagine the value of diversity through inclusion, celebrating the extraordinary talent and creativity of local and international artists of varying abilities.

No Limits Theme Banner (1).jpg

“No Limits” 2026 presents 11 groundbreaking works across music, theatre, dance and film, with a total of 29 performances and events. The season also features over 20 Jockey Club “No Limits” Education and Community Programmes, including school tours, workshops, public showcases and an international symposium. These events aim to foster greater understanding, creativity and connection across communities.

This year marks an important milestone for “No Limits” as it collaborates for the first time with two of Hong Kong’s flagship performing arts companies—the Hong Kong Dance Company and the Hong Kong Chinese Orchestra—to present multidisciplinary inclusive programmes. These trailblazing partnerships highlight the growing integration of inclusivity into Hong Kong’s mainstream cultural landscape.

Celebrating its eighth edition, the theme of this year’s “No Limits” – “All of Us, All Ways” – reflects its commitment to promoting diversity and connecting people through the arts. By embracing differences and fostering inclusive collaborations, “No Limits” seeks to inspire new perspectives and unlock the imaginative possibilities that diversity brings. Building on the success of the 2025 “No Limits”‘ International Symposium, the programme continues to promote the growth of an Asian network of inclusive arts partners. In this way, “No Limits” reaffirms its vision of becoming a transformative force both locally and regionally.

Tickets to all performances are now available at URBTIX. A limited early bird offer of a 20% discount on all standard price tickets will be available until 5 January 2026. Half-price tickets are available for full-time students, people with disabilities and one companion, and Comprehensive Social Security Assistance (CSSA) recipients. (Link: www.urbtix.hk/series/124?bannerCode=NL2026)

Community programmes, including public showcases and screenings, are free of charge and open to everyone. Selected online programmes can also be accessed for free on the official website, https://www.nolimits.hk.

In collaboration with the Arts with the Disabled Association Hong Kong, “No Limits” will once again provide a range of accessibility services, including audio description, Hong Kong sign language interpretation, accessible captions, braille and audio booklets, and relaxed performances. Additional wheelchair seats may be available in some venues. Guide dogs are welcome.

To carry the spirit of inclusion beyond the stage, “No Limits” is launching a series of inclusive-themed plush toys. Purchasers of tickets worth HK$500 or more in a single transaction will receive a souvenir plush toy, while stocks last.

In-venue Programme

Opening Programme: The Nature of Why

The internationally acclaimed Paraorchestra, the world’s first professional inclusive orchestra, presents an immersive symphonic dance-theatre experience inspired by Nobel Prize-winning physicist Richard Feynman. Featuring live orchestral music, contemporary dance and audience interaction, this groundbreaking performance challenges perceptions of inclusion and art.

Dates: 27 February – 1 March 2026, Auditorium, Kwai Tsing Theatre

Wayfaring Beyond

A unique outdoor performance co-produced by the Hong Kong Dance Company and the China Hong Kong Para Dance Sport Association. Drawing on Daoist philosophy, this powerful collaboration blends traditional Chinese dance and wheelchair dance sport, exploring the beauty of diverse physicality and the freedom that transcends the body.

Dates: 28 February – 1 March 2026, Parade Ground, Tai Kwun

Light and Shadow on Strings

The Hong Kong Chinese Orchestra, in collaboration with visually impaired erhu prodigy Yang Enhua, presents a mesmerising concert of traditional and contemporary Chinese string music. The programme also includes a newly commissioned work inspired by the experiences of visually impaired individuals.

Date: 28 March 2026, Auditorium, Tsuen Wan Town Hall

Two Blind Women in the Snowy Tokugawa Nights – Sleeping Fires

Commissioned by “No Limits”, director Kuro Tanino creates a poignant and visually stunning theatrical work inspired by the lives of blind massage therapists in ancient times. This world premiere reflects on themes of trust, independence and belonging.

Dates: 27–29 March 2026, Studio Theatre, Hong Kong Cultural Centre

Zer-Brech-Lich

Swiss choreographer Alessandro Schiattarella presents a witty and heartfelt musical theatre performance led by three disabled performers. Through original music and dance, the production transforms vulnerability into a celebration of strength and diversity.

Dates: 13–15 March 2026, Black Box Theatre, Kwai Tsing Theatre

Precarious Moves

Vienna-based artist Michael Turinsky performs a thought-provoking solo exploring the choreography of resistance and the relationship between body, time and space. This work challenges societal expectations surrounding disabled bodies.

Dates: 17–18 March 2026, The Box, Freespace, WestK

Harmonia

This award-winning dance work by Theatre Bremen and choreographer Adrienn Hód dismantles conventional notions of the body in dance. Featuring a diverse cast of performers with and without disabilities, the piece highlights the possibilities of inclusive choreography.

Dates: 21–22 March 2026, The Box, Freespace, WestK

Free Screenings and Online Programmes

“No Limits” 2026 offers an exciting selection of films and documentaries that highlight themes of inclusion, resilience and the human experience. These screenings are free of charge, with in-venue viewings at Tai Kwun Laundry Steps and online accessibility through the “No Limits” website*.

A Space in Time (Riccardo Servini and Nick Taussig)

A heartfelt documentary capturing the journey of a family raising two sons with Duchenne muscular dystrophy. Through interviews and candid home videos, this film explores their resilience and the role of supportive communities.

Dates: 17 January (Sat) & 18 January (Sun), 3:20 PM
Language: English with Chinese and English subtitles, Cantonese dubbing, and audio description in Cantonese.

Away from Her (Sarah Polley)

A poignant feature film about love, memory and loss, as a married couple of over 40 years faces the challenges of early-onset Alzheimer’s disease. Based on the short story The Bear Came Over the Mountain by Alice Munro.

Dates: 17 January (Sat) & 18 January (Sun), 4:50 PM
Language: English with Chinese and English subtitles, Cantonese dubbing, and audio description in Cantonese.

Lapse (Caroline Cavalcanti)

A Brazilian short film about friendship and understanding, as two teenagers—one a deaf skateboarder, the other a rap enthusiast—form a connection through sign language and shared struggles.

Dates: 28 February (Sat) & 1 March (Sun), 5:45 PM; 7 March (Sat) & 8 March (Sun), 3:10 PM
Language: Portuguese with Chinese and English subtitles, Cantonese dubbing, and audio description in Cantonese.

Fujiyama Cottonton (Taku Aoyagi)

A reflective Japanese documentary set at Mirai Farm, a facility for differently-abled individuals, exploring their daily lives, creativity and the beauty of community. Inspired by the French film On the Adamant.

Dates: 7 March (Sat) & 8 March (Sun), 3:35 PM
Language: Japanese with Chinese and English subtitles, Cantonese dubbing, and audio description in Cantonese.

*From 30 March to 25 May 2026, all films will be available for free online viewing. Each film includes Chinese and English accessible subtitles, Cantonese and English dubbing, and audio description services in both languages.

Audiences can visit https://www.nolimits.hk to stream these films free of charge during the scheduled dates.

Jockey Club “No Limits” Education and Community Programme

The Jockey Club “No Limits” Education and Community Programme continues to promote inclusion and creativity through a range of impactful initiatives, including community showcases, a school touring programme, a creative training programme, an international symposium and an innovative research scheme.

Community Showcases and Live Screenings

Taking place on 17–18 January and 7–8 March 2026 at the Laundry Steps, Tai Kwun, these showcases feature performances co-created by participants of the Pilot Creative Training Programme and community organisations. The events also include live performances, post-show sharing sessions and film screenings. Accessibility features include audio description, sign language interpretation and subtitles in Chinese and English. Admission is free, with no registration required.

Pilot Creative Training Programme

Running from September to October 2025, this programme, in collaboration with Candoco Dance Company (UK), offers two pathways:

  • Fundamental Course: For teaching artists with 0–2 years’ experience, focusing on inclusive teaching methods.
  • Advanced Course: For experienced teaching artists, exploring reflective and innovative practices.

Participants will undertake three-month placements at community centres, co-creating workshops with individuals of all abilities. The results will be performed during the Community Showcases.

School Touring Programme: “The Ways We Move”

In March 2026, this a cappella concert will tour schools, featuring choirs of mixed abilities performing original and popular songs inspired by real-life stories. The performance explores how we express ourselves through our bodies and emotions, inviting students to participate in group singing and movement activities. Schools can enquire at outreach@nolimits.hk.

International Symposium: “The Way Forward: A Humanistic–Tech Framework for Inclusive Innovation”

To be held on 8 March 2026 at JC Cube, Tai Kwun, this symposium brings together experts from arts, technology, urban planning, healthcare and community advocacy to discuss how creativity and technology can drive inclusion. Topics include democratising access to the arts, sensory design in urban planning, and co-creation with disabled individuals. The event is free of charge with Cantonese and English interpretation provided.

Local Creative Research and Development Scheme

This nine-month initiative pairs local artists with individuals of different abilities to co-create new works exploring inclusive practices. Highlights include:

  • Jezrael Lucero and Daniel Chu: Exploring Lucero’s journey as a blind Filipino jazz musician.
  • Miu Law and Sham Chung-tat: Redefining mapmaking through sound and tactile experiences.
  • Amy Chan and Chu Po: Investigating creativity and societal norms through ceramics and light.
  • Tsz Wai-pun and Nathan Fong: Combining robotics and puppetry to innovate storytelling.

The results will be presented as part of “No Limits” 2026, showcasing the potential of inclusive arts to audiences.

Arts Accessibility Services

“No Limits” continues its collaboration with the Arts with the Disabled Association Hong Kong to offer a range of accessibility services, including audio description, Hong Kong sign language interpretation, accessible captions, braille and audio booklets, and relaxed performances; additional wheelchair seats may be available in some venues. Guide dogs are welcome.

For more event details, please visit the “No Limits” website: www.nolimits.hk
Click here for programme details: www.nolimits.hk/programme
Urbtix: https://www.urbtix.hk/series/124?bannerCode=NL2026
Click here to download programme images.

Appendix

Programme

Date Programme Performer/ Director Venue
Highlights
27 Feb – 1 Mar 2026 The Nature of Why Paraorchestra Auditorium,

Kwai Tsing Theatre

28 Feb – 1 Mar 2026 Wayfaring Beyond Hong Kong Dance Company & China Hong Kong Para Dance Sport Association Parade Ground,

Tai Kwun

13-15 Mar 2026 Zer-Brech-Lich Alessandro Schiattarella and Ensemble Black Box Theatre,

Kwai Tsing Theatre

17-18 Mar 2026 Precarious Moves Michael Turinsky The Box,

Freespace, WestK

21-22 Mar 2026 Harmonia Unusual Symptoms / Theatre Bremen / Adrienn Hód The Box,

Freespace, WestK

27-29 Mar 2026 Two Blind Women in the Snowy Tokugawa Nights – Sleeping Fires Kuro Tanino Studio Theatre, Hong Kong Cultural Centre
28 Mar 2026 Light and Shadow on Strings Hong Kong Chinese Orchestra (Chamber Ensemble)

Yang Enhua (Solo and Ensemble)

Auditorium,

Tsuen Wan Town Hall

“No Limits” International Symposium
8 Mar 2026 The Way Forward: A Humanistic–Tech Framework for Inclusive Innovation JC Cube, Tai Kwun

Free Screenings and Online Programmes

In-venue Free Screening @Laundry Steps, Tai Kwun Free screening available on “No Limits” website Programme Director
17-18 Jan 2026 30 Mar – 25 May 2026 A Space in Time Riccardo Servini & Nick Taussig
17-18 Jan 2026 30 Mar – 25 May 2026 Away From Her Sarah Polley
28 Feb – 1 Mar,

7 – 8 Mar 2026

30 Mar – 25 May 2026 Lapse Caroline Cavalcanti
7 – 8 Mar 2026 30 Mar – 25 May 2026 Fujiyama Cottonton Taku Aoyagi

Hashtag: #NoLimits

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About the Hong Kong Arts Festival

Launched in 1973, the Hong Kong Arts Festival is a major international arts festival committed to enriching the cultural life of the city. In February and March every year, the Festival presents leading local and international artists from all genres of the performing arts, giving equal importance to great traditions and contemporary creations. The Festival also commissions and produces work in theatre, music, chamber opera and contemporary dance by Hong Kong’s own creative talents and emerging artists, many of which have subsequently had successful runs in Hong Kong and overseas. Every year, the Festival also presents more than 250 “PLUS” and educational activities that offer diverse arts experiences to the community as well as tertiary, secondary and primary school students. In addition, through the “No Limits” project co-presented with The Hong Kong Jockey Club Charities Trust, the Festival strives to create an inclusive space for people of different abilities to share the joy of the arts together.

For more information about the Hong Kong Arts Festival, please visit .

About “No Limits”

Launched in 2019 and co-presented by the Hong Kong Arts Festival and The Hong Kong Jockey Club Charities Trust, “No Limits” offers barrier-free performances and events, and explores and promotes inclusiveness and understanding through the arts.

In 2026, the eighth edition of “No Limits” showcases a series of fascinating programmes of music, dance, theatre and film by international and Hong Kong artists of different abilities.

“No Limits” 2026 presents accessible in-venue performances, free film screenings and a symposium, as well as education and community programmes for young people, highlighting creativity and talent in a variety of forms.

For more information about “No Limits”, please visit