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Chubb Wealth Q4 2026 Investment Outlook: A Less Synchronized World


HONG KONG SAR – Media OutReach Newswire – 5 October 2026 – Chubb Wealth released its Q4 2026 Investment Outlook, A Less Synchronized World, highlighting a resilient but increasingly uneven global economy and a broader opportunity set across equities, fixed income, alternatives and Asian markets.

According to Chubb Wealth, the global economy remains resilient despite ongoing uncertainty in the Middle East, but that resilience is not uniform. The U.S., Europe, Japan and China are each facing different growth drivers and constraints. Energy uncertainty, trade restrictions, fiscal spending and large infrastructure requirements may keep inflation more volatile than in the decade before the pandemic.

Ben Rudd, General Manager of Chubb Wealth, says: “As investors assess their portfolios going into 2027, the answer is not to retreat to cash in the face of uneven growth and continued investment uncertainty. The opportunity set is broader than it has been for years, so the focus should be on building portfolios that can earn returns from multiple sources, including alternatives.”

Chubb Wealth remains generally constructive on risk assets and highlights four investment priorities for Q4 2026:

  • Income matters again: Starting bond yields allow fixed income to contribute meaningfully to total portfolio returns.
  • Follow the artificial intelligence (AI) investment dollar: The opportunity is moving from chips into data centers, cooling, power, grids, software and ultimately productivity.
  • Tap into Asia’s diversified investment cycles: China, Japan, Korea/Taiwan, India and Southeast Asia offer different policy, valuation, earnings and currency drivers.
  • Give alternatives a portfolio role: Private credit, infrastructure, hedge funds and private equity should each address a specific portfolio objective.

Chubb Wealth remains neutral on global equities and bonds. In fixed income, we prefer higher starting yields, including high-yield, Asian and USD emerging market bonds, and believe bonds can once again be owned primarily for income. We believe a weaker U.S. dollar will remain a key theme, supporting greater geographic and currency diversification.

In alternatives, infrastructure remains the favored allocation, supported by electrification, energy security, renewable generation, grid modernization and digital infrastructure.

For the full report, please visit: https://www.chubbwealth.com/hk-en/wealth-insight/q4-2026-outlook.html

Hashtag: #Chubb #ChubbWealth

The issuer is solely responsible for the content of this announcement.

About Chubb Wealth

Chubb Wealth is a Hong Kong wealth management platform with a mission to empower high-net-worth investors to achieve their long-term wealth goals and aspirations with ease. As a global insurer-backed wealth management platform, Chubb Wealth offers clients seamless digital investing and wealth management capabilities, access to a carefully curated range of funds, and bespoke advisory services. Chubb Wealth is operated by Chubb Investment Management (HK) Limited, an indirect wholly owned subsidiary of Chubb Limited. Additional information can be found at

About Chubb

Chubb is a world leader in insurance. With operations in 54 countries and territories, Chubb provides commercial and personal property and casualty insurance, personal accident and supplemental health insurance, reinsurance and life insurance to a diverse group of clients. The company is defined by its extensive product and service offerings, broad distribution capabilities, exceptional financial strength and local operations globally. Parent company Chubb Limited is listed on the New York Stock Exchange (NYSE: CB) and is a component of the S&P 500 index. Chubb employs approximately 45,000 people worldwide. Additional information can be found at: .

Disclaimer

Chubb Wealth only conducts regulated activities in Hong Kong, and the information herein is only intended for distribution to and used by recipients located in territories where such use does not constitute a violation of applicable laws and regulations.

The views and opinions herein are current as of the date of this news release and are solely for general informational purposes only and do not consider any specific investment objectives, financial situation and/or particular needs of any specific person who may receive this document. Reliance upon information in this news release is at the sole discretion of the reader, and Chubb Wealth shall not be liable for any damages arising out of any person’s reliance upon this information. Please be cautioned that investment involves risks, and you may lose part or all of your investment. Please consult your own professional adviser and consider your own financial objectives, risk tolerance and circumstances before making any investment decisions. This news release discusses general market activity, industry or sector trends, or other broad-based economic, market, or political conditions and should not be construed as research or investment advice. This news release is not intended as a promotion, an offer, a solicitation of an offer, or a recommendation, to deal in any securities or any financial instruments or services.

This news release represents the views and opinions solely of Chubb Wealth and not of its indirect parent company, Chubb Limited, or any other subsidiary or representative of Chubb Limited.

Licensing information

Chubb Investment Management (HK) Limited (trading as “Chubb Wealth”) is an indirect wholly-owned subsidiary of Chubb Limited, and is licensed (CE No. AVR438) under the Hong Kong Securities and Futures Ordinance (Cap. 571) to carry on business in Type 1 (Dealing in Securities), Type 4 (Advising on Securities) and Type 9 (Asset Management) regulated activities in Hong Kong.

Thailand’s LTR Visa Hits 12,000 Approvals in Four Years, Adding USD 1.28 Billion to the Economy


BANGKOK, THAILAND – Media OutReach Newswire – 5 October 2026 – The Long-Term Resident (LTR) visa has attracted 12,010 high-potential foreigners to Thailand in four years, generating approximately USD 1.28 billion (THB 43 billion) in economic value, according to the Board of Investment (BOI). The visa is a key mechanism for attracting executives and highly skilled personnel for future industries while increasing purchasing power and stimulating domestic spending and economic activity. A new online system now links services from four government agencies in an integrated process.

Mr. Narit Therdsteerasukdi, Secretary General of the Thailand Board of Investment (BOI)
Mr. Narit Therdsteerasukdi, Secretary General of the Thailand Board of Investment (BOI)

Introduced in September 2022 to attract high-potential foreigners to reside and conduct economic activities in Thailand, the LTR visa program has generated an average economic value of more than USD 107,000 (THB 3.6 million) per recipient, according to BOI data. The calculation covers visa fees, spending in Thailand by visa holders, direct investment, and tax revenue from highly skilled professionals.

Amid intensifying global competition for highly skilled personnel, the LTR visa is an important mechanism for bringing global talent into Thailand. This is particularly relevant as the country prepares for a new wave of investment in advanced-technology industries, including semiconductors and advanced electronics, digital technology and AI, humanoid robotics, aviation, and biotechnology.

“The LTR visa is a strategic pillar to attract global talent as Thailand absorbs a new wave of advanced technology investments,” said Narit Therdsteerasukdi, Secretary General of the Board of Investment. “Drawing top-tier executives and technical specialists from around the world is vital to strengthening our national competitiveness and securing technology transfers from international partners.”

Approved LTR visa recipients primarily come from leading economies. The United States accounts for the largest group, with more than 2,400 approvals, followed by Japan with more than 1,300 and the United Kingdom with more than 1,000. Japanese nationals comprise a notable share of the specialist bracket, aligning with Japan’s heavy footprint in Thailand’s automotive and precision-electronics supply networks.

The 12,010 approved LTR visa recipients fall into five categories: 1,779 Highly-Skilled Professionals; 1,043 Work-from-Thailand Professionals, who work from Thailand for overseas employers; 737 Wealthy Global Citizens; 4,561 Wealthy Pensioners; and 3,891 Dependents of recipients in the first four categories.

Among recipients in the Highly-Skilled Professionals and Work-from-Thailand Professionals categories, 54% hold executive-level positions and 36% are professionals in various fields; the remainder are at the technical level. Applicants in each category must meet specific criteria, such as requirements relating to assets, income, investment evidence, work experience, and health insurance, and undergo rigorous checks by the relevant agencies.

To handle rising application volumes and remove long-standing administrative bottlenecks, the BOI rolled out an integrated digital processing portal in September 2026. The platform centralizes review procedures across four primary state bodies: the Department of Consular Affairs, the Immigration Bureau, the Department of Employment, and the Revenue Department.

Complementing the portal, the Thailand Investment and Expat Services Center (TIESC), a one-stop service center, is located on floors 6-7 of the Parade Zone at One Bangkok. “The center is intended to strengthen Thailand’s competitiveness in continuously attracting high-potential talent from around the world,” said Mr. Narit.

In addition to attracting foreign talent through the LTR visa, BOI also facilitates visas and work permits for executives and personnel working in BOI-promoted businesses through the BOI Visa, and offers the Smart Visa for startups. BOI also supports the skills development of Thai personnel through the Skill Bridge measure, and helps Thai entrepreneurs adopt modern technology to enhance their competitiveness through the Business Transformation measure. These measures work hand in hand to attract international experts, develop Thai personnel, and upgrade Thai businesses, strengthening Thailand’s readiness for the transition to a new economy driven by technology and innovation.


Note: Currency conversions are based on the Bank of Thailand’s average selling rate of approximately 1 USD = 33.6 THB.

Hashtag: #Thailandboardofinvestment #BOI #FDI #Investment

The issuer is solely responsible for the content of this announcement.

Thailand Board of Investment (BOI)

Established in 1966, the Office of the Board of Investment (BOI) has played an important role for more than 60 years in promoting value-creating investment by both foreign and Thai investors, strengthening competitiveness and supporting Thailand’s sustainable economic restructuring toward the new economy.

Laos Hands Over Nearly 200 Suspected Scammers to Thailand, China in Early October

Bokeo authorities handed over 78 Thai suspects to Thai officials at the 4th Lao-Thai Friendship Bridge. Bokeo Province, Laos. 01 October 2026. (Photo: Lao Security News)

Laos handed 196 Chinese and Thai nationals back to authorities in their home countries on 1 October, as authorities continue a nationwide crackdown on cybercrime and scam operations.

The group was transferred in two separate handovers in Bokeo. Most of them, 189 people, face allegations linked to cybercrime or telecom fraud, while seven were accused of entering Laos illegally.

At the Boten-Mohan International Checkpoint in Luang Namtha Province, Lao officials handed 118 Chinese nationals to Chinese authorities. The group included 113 people accused of cybercrime and five accused of illegal entry. They will face deportation and further legal proceedings in China.

Later that day, 78 Thai nationals were handed over at the 4th Lao-Thai Friendship Bridge. Thai authorities will handle the cases from there. Among the group, 76 are accused of working with call center scam gangs, while two face illegal entry charges.

Lao authorities also handed over equipment seized from the group, including 107 desktop computers, dozens of personal phones, and three tablets.

Recent Handovers and Raids

The Bokeo transfers are part of a wider series of handovers in recent weeks.

In Vientiane, authorities handed 25 Thai nationals, including 11 women, to Thai police on 30 September at the 1st Lao-Thai Friendship Bridge. They face allegations involving cybercrime and online gambling.

Another 129 Thai nationals were transferred to Thai authorities at the same bridge on 17 September.

Meanwhile, police in Savannakhet were dealing with suspected illegal activity at home.

On 28 September, officers raided two rental properties in Kaysone Phomvihane City, detaining 17 people.

At one property in Phonsavang Tai Village, police detained 14 Chinese nationals and one Lao national and seized 38 desktop computers and 41 smartphones.

At a second property in Sanamxay Village, police detained two Lao nationals and seized kratom leaves and 22,963 bottles of cough syrup.

The latest operations add to a much larger crackdown that has swept across Laos this year. Since January, authorities have detained more than 6,200 suspected scammers from more than 25 nationalities.

Dahua and PARC Foundation Join Forces to Protect Dreams and Empower Young Filipino Talent

TAGUIG CITY, Philippines, Oct. 5, 2026 /PRNewswire/ — Every young person deserves the opportunity to discover their talent, pursue their dreams, and build a brighter future. Yet for children from low-income families and children with special needs, access to opportunities can often be limited by circumstances beyond their control.

Recognizing the importance of giving these young talents a chance to be seen, heard, and supported, global security brand Dahua Technology is partnering with the PARC Foundation, a nonprofit organization dedicated to helping young people develop their potential through music and the arts.

Through the “WITHS You, Protect Dreams” campaign, Dahua is extending its commitment beyond protecting people and places to supporting something equally valuable—the dreams and potential of young people who may face greater barriers in pursuing them.

The partnership supports talented children, including those from underserved families and children with special needs, who have a passion and ability in music and the arts. For some of these young talents, access to instruments, training, teachers, and learning opportunities may simply be out of reach for their families. By helping provide these resources, the initiative gives them a chance to develop their abilities, build confidence, express themselves, and explore what they may be capable of achieving.

For children with special needs in particular, music and the arts can provide meaningful ways to communicate, connect with others, and express themselves. For families with limited resources, access to quality arts education can also open a door that might otherwise remain closed—not simply as an artistic pursuit, but as an opportunity for children to discover their strengths and build confidence in themselves.

Their stories remind us that talent can be found everywhere, but opportunity is not always equally accessible.

As part of the campaign, Dahua will donate PHP 25 to the PARC Foundation for every participating Dahua WITHS product purchased during the campaign period. Through this initiative, customers can make their purchases part of a meaningful cause, while Dahua contributes additional support to help young talents access the resources they need.

“Through WITHS You, Protect Dreams, we want to extend our commitment to protecting what matters most—not only people and places, but also the dreams and potential of young people. By working together with PARC Foundation, we hope to help create more opportunities for young talents to learn, grow, express themselves, and pursue their dreams,” said Dahua Philippines.

The initiative reflects Dahua’s belief that security goes beyond technology. It is also about creating a more supportive environment where people can pursue what matters to them and build a better future.

Together with PARC Foundation, Dahua hopes to help more young talents be seen, heard, and supported.

Every dream deserves a chance. Every talent deserves support. And Dahua is WITHS them.

Follow Dahua Philippines on Facebook to learn more about the campaign.

Patience Is Being Repriced as Government Borrowing, AI And Energy Compete For Long-Term Capital: GIC CEO Lim Chow Kiat

Fifth WMI Global-Asia Family Office Summit examines portfolio resilience and next-generation readiness as WMI research identifies meaningful participation as a key marker of preparedness


SINGAPORE – Media OutReach Newswire – 5 October 2026 – Government borrowing, the artificial intelligence (AI) build-out and the overhaul of energy systems are all competing for the same pool of long-term money at a time when lenders demand more compensation to commit for long, WMI Chairman and GIC CEO Mr Lim Chow Kiat said today at the fifth WMI Global-Asia Family Office Summit.

Lim Chow Kiat Press photo

Mr Lim said: “There is no shortage of capital in the world. What is shorter is patience, and patience is being repriced.” He added:”The advantage of long-term capital—whether it is a family’s wealth or a country’s reserves—is that we do not have to predict the outcome. We have to be prepared for it, selective in what we own, and ready to move when others cannot.”

In his opening keynote, Mr Lim encouraged investors to look beyond the level of bond yields to what is driving them: stronger growth and investment, or doubts about inflation and public finances. He noted that AI has become a credit story as well as an equity one, with more of the build-out funded by debt. As outcomes widen across AI and energy, he said granularity matters more than ever, with GIC looking at assets one at a time rather than buying a broad theme.

Family offices navigate a new era of disruption and opportunity
Held under the theme Legacy in Action: Capital for the New Horizon, the two-day Summit will welcome close to 650 participants from across the family office ecosystem to discuss investing, family office governance, leadership and social impact.

The opening-day Single Family Office Forum brings together more than 240 participants, comprising families and their family office teams from Asia, Australia, Europe and the United States, at different stages of building, stewarding and carrying forward their family enterprises and legacies.

Over five years, the Summit has grown alongside Singapore’s family office ecosystem into a trusted community where families, investors and professionals connect, learn from one another and explore opportunities together.

Preparing the next generation for stewardship
Alongside discussions on the investment landscape, the Summit examined how families can prepare the next generation to assume responsibility for capital, enterprise and legacy.

In her welcome address, Ms Foo Mee Har, CEO of WMI, launched Stewardship by Design: Preparing Asia’s Next Generation for Leadership and Impact, a study conducted jointly with academics from Harvard Business School and the University of Chicago Booth School of Business.

The research draws on responses from about 150 family offices, primarily in Asia. It compares their responses with those of family offices worldwide, with the majority from the Americas.

According to the study, 49% of Asian respondents consider the next generation prepared, compared with 52% in the comparison group. The figures are close, but they also reveal a shared challenge: only about half of respondents see the next generation as ready.

Ms Foo said: “Our study found that when next-generation members have the opportunity to contribute alongside senior family members on consequential decisions, families are almost seven times more likely to see them as ready.”

“The next generation does not develop judgement by waiting on the sidelines for responsibility to arrive, yet many families face a practical challenge. They want to prepare the next generation, yet they are not ready to hand over major decisions. Nor do they have to.”

Ms Foo added: “But there is no single structure that every family should follow. Asian families differ in size, history and complexity. What matters is having a clear path for development that fits the family’s circumstances.”

Translating research into practical support
To put these findings into practice, Ms Foo announced two distinct new WMI programmes to help prepare the next generation.

The first is PATH: Purpose, Aspiration, Trust and Heritage, a new programme for next-generation members of business-owning and wealth-owning families.

PATH will help participants explore their values and aspirations, deepen their understanding of enterprise, ownership and governance, and consider the different roles they can play as family stewards. They will identify practical next steps towards making a meaningful contribution to their families.

Connecting family offices with innovation
Ms Foo also shared with participants that WMI is working to connect family offices with globally leading innovation ecosystems.

Through learning journeys and direct engagement with founders, investors, researchers and technology leaders, family offices and next-generation members will get firsthand exposure to emerging technologies and business models, helping them understand the latest developments and where new opportunities may lie.

Insights from global business and technology leaders
Day One also features Dr David K. Lam, Founder of Lam Research and Chairman and CEO of Multibeam Corporation; Mr Mark Lee, CEO of Singlun; and Ms Cindy Karim, Principal of the Karim Family Foundation, alongside other prominent family principals, investors and technology leaders.

Discussions span emerging technologies and investment judgement, next-generation leadership, family enterprise, governance and long-term impact.

Deputy Prime Minister Gan Kim Yong, Minister for Energy, Trade and Industry (Trade), and Chairman of the Monetary Authority of Singapore will attend the Summit as Guest of Honour later today.

The WMI Global-Asia Family Office Summit continues on 6 October 2026 with the Partners Forum, bringing together financial institutions, advisers and other professionals supporting families across investments, governance, succession, philanthropy and legacy.

For Mr Lim Chow Kiat’s full speech, click here.
For Ms Foo Mee Har’s full speech, click here.
To download the report, click here.

Hashtag: #WMI

The issuer is solely responsible for the content of this announcement.

About WMI

Established in 2003, the Wealth Management Institute (WMI) is committed to building capabilities for investing in a better tomorrow. Founded by GIC and Temasek, our vision is to be Asia’s Centre of Excellence for wealth and asset management education and research.

WMI provides a comprehensive suite of practice-based certification and diploma programmes and collaborates with leading universities for master’s degrees. With over 20,000 annual enrolments, WMI serves a diverse community of professionals across Asia—including wealth and asset managers, family offices, and professionals in tax, legal, compliance, and financial regulation across more than 160 programmes. WMI is recognised as Singapore’s lead training provider for private banking and wealth management.

WMI helms the Global-Asia Family Office (GFO) Circle, a trusted network platform that builds capabilities and fosters community within the family office sector. The GFO Circle is supported by the Singapore Economic Development Board (EDB) and the Monetary Authority of Singapore (MAS). WMI also leads the Asia Centre for Changemakers (ACC), supported by Temasek Trust and the Philanthropy Asia Alliance (PAA). The ACC aims to build capacity and nurture a strong pipeline of active and informed changemakers with a focus on Asia.

Benchmarking Asia’s Global Hubs: Hong Kong General Chamber of Commerce Unveils the Asian Cities Internationality Index 2026

Tracking 11 major cities to assess internationality, the index provides data-driven insights to shape urban policy, guide business strategy, and encourage regional exchange

HONG KONG SAR – Media OutReach Newswire – 5 October 2026 – The Hong Kong General Chamber of Commerce (HKGCC) and independent research firm Ipsos launched the second edition of the Asian Cities Internationality Index (ACII), a comprehensive evaluation of 11 major hubs across seven core dimensions. By assessing cities on Business and Economy, Quality of Life, Infrastructure and Connectivity, Innovation and Ideas, Human Capital Diversity, Cultural Interaction, and Government and Legal System for Business, the multifaceted index equips policymakers and business leaders with actionable strategies to elevate Asia’s standing in the global economy.

This year, Hong Kong continued to be Asia’s top international city and the region’s premier gateway for regional and global operations. Out of a maximum score of 100, Hong Kong ranked first with 74.6 (up from 73.7 in 2025), followed by Singapore and Seoul. Elsewhere across the region, Tokyo adjusted to fourth, while Shanghai retained fifth, leading the region in innovation. Bangkok, Kuala Lumpur and Taipei each demonstrated their distinct strengths, as Mumbai rose to ninth place, representing its growing emergence as a globally oriented business hub. Jakarta and Ho Chi Minh City rounded out the list at 10 and 11 respectively.

“By launching the ACII 2026, HKGCC provides a vital, data-driven tool to understand the shifting competitive landscape in Asia”, said HKGCC Chairman Jacob Kam. “Hong Kong’s top ranking proves our fundamental resilience and underscores that global businesses continue to view the city as the ultimate bridge between East and West. From a broader perspective, the ACII provides the strategic insights necessary for Asian cities to collaborate and complement one another’s strengths, fostering a formidable regional economic cluster.”

Download the full report at: www.chamber.org.hk

Hashtag: #HKGCC

The issuer is solely responsible for the content of this announcement.

About Hong Kong General Chamber of Commerce (HKGCC)

For 165 years, the Hong Kong General Chamber of Commerce has been the voice of business, growing together with Hong Kong and the business community. Our mission is to promote, represent and safeguard the interests of the business community in Hong Kong, and at the same time provide support, networks, training and business services to help the business community grow. For more details, please visit .

The Coffee Bean & Tea Leaf® Turns 63 and Sets a New Direction for Its Next Chapter of Growth

Global anniversary campaign marks the first step of the brand’s transformation

SINGAPORE, Oct. 5, 2026 /PRNewswire/ — On the eve of its 63rd anniversary, The Coffee Bean & Tea Leaf® (CBTL) has unveiled a global anniversary campaign, the first milestone in its brand transformation journey. For 63 years, CBTL has brought people together over specialty coffee and tea. Now it’s handing the pen to a new generation of artists and creators to write what’s next.

The Coffee Bean & Tea Leaf® is celebrating 63 years of helping people find their flavor.
The Coffee Bean & Tea Leaf® is celebrating 63 years of helping people find their flavor.

At the heart of the refresh are the principles that have guided CBTL from the start: a vision to deliver simply the best coffee and tea experience in every community it serves, and a purpose to help people find their flavor, turning an ordinary day into something a little more special. It builds on what has always set CBTL apart: real craft, made by real people.

That spirit comes to life in a refreshed visual identity that pairs contemporary energy with 63 years of coffee and tea craft. It’s bold, expressive and unmistakably CBTL.

Real people are front and center. The campaign features emerging artists, the CBTL brew crew and customers, each with a story to tell across campaign assets, on- and offline. Across participating markets, it will take shape in different ways, reflecting the culture and communities of each place it touches.

“Turning 63 is a moment to look ahead as much as looking back. We’ve built something lasting on craft and community, and now we’re evolving the brand to matter as much to the next generation as it has to the last. This anniversary is the first step of a bigger transformation, and the start of our next chapter of growth.” – Ken Lingan, Chief Executive Officer, The Coffee Bean & Tea Leaf®

“We’re tuned in to culture and the people driving it, and we’re leaning into our role as a creator brand. Craft and self-expression have been part of who we are for 63 years, and this anniversary is as much about celebrating our past as it is about inviting the next generation to bring their own flavor.” – Anshul Laroia, Global Head of Marketing, The Coffee Bean & Tea Leaf®

The Story Continues, One Drink at a Time.

The 63rd anniversary campaign marks the first step in CBTL’s brand transformation, building on more than six decades of craft, community and heritage. As it unfolds across participating markets, CBTL will continue to invite a new generation to Find Their Flavor.

Keep up with the 63rd Anniversary on cbtl.com/makeityours.

About The Coffee Bean & Tea Leaf®
Headquartered in Asia and a proud member of the Jollibee Group, The Coffee Bean & Tea Leaf® is a modern, global specialty coffee and tea house. With a legacy that began in Southern California in 1963, The Coffee Bean & Tea Leaf® now operates in over 1,200 locations across more than 20 countries. We source the finest coffees and teas from local communities and then handcraft every beverage to bring out the freshest flavors. As the creator of The Original Ice Blended®, we continue to innovate to enable people everywhere to enjoy the classics as well as new flavors, both in our cafés and at home. For more information, visit https://corporate.thecoffeebeanandtealeaf.com.

 

Symphony™ Randomized Controlled Trial Demonstrates Significantly Improved Healing of Diabetic Foot Ulcers

Published multicenter study found higher complete wound closure rates and faster healing with Symphony plus standard of care

AUCKLAND, New Zealand, Oct. 5, 2026 /PRNewswire/ — Aroa Biosurgery Limited (ASX: ARX), a soft tissue regeneration company, today announced positive results from a prospective, multicenter randomized controlled trial (RCT) of Symphony™, published in the International Wound Journal.

The study enrolled 143 patients across 10 U.S. sites and found that adding Symphony to standard of care significantly improved healing outcomes for diabetic foot ulcers (DFUs):

  • 55% of DFUs achieved complete wound closure within 12 weeks, compared with 35% receiving standard of care alone (p=0.039).
  • Mean time to complete wound closure was reduced by 7.8 days: 65.4 days with Symphony plus standard of care, compared with 73.2 days with standard of care alone (p=0.041).

The trial enrolled patients with challenging Wagner Grade 1 or 2 DFUs, ranging from ulcers involving the full thickness of the skin to deeper ulcers extending into ligaments, tendons, joint capsules or deep fascia. Patients were randomly assigned to receive weekly Symphony plus standard of care or standard of care alone, for up to 12 weeks or until complete wound closure.

The findings provide high-quality clinical evidence supporting Symphony’s effectiveness and are expected to support product differentiation, clinical adoption and evolving U.S. reimbursement requirements.

“New technologies and high-quality randomised clinical evidence are essential if we are to continue improving outcomes for patients with diabetic foot ulcers,” said lead investigator Dr David Armstrong. “The Symphony trial demonstrates that combining a novel extracellular matrix bioscaffold with high molecular weight hyaluronic acid can significantly improve wound healing when added to good standard of care. Studies like this help clinicians make informed treatment decisions based on robust evidence.”

“This is a major milestone for Symphony. The study delivered clear, statistically significant results: adding Symphony to standard of care for DFUs increased complete wound closure at 12 weeks to 55%, compared with 35% for standard of care alone, and reduced mean healing time by 7.8 days,” said AROA CEO Brian Ward.

“The multicentre design and involvement of recognised key opinion leaders strengthen the evidence’s credibility and clinical relevance. Amid growing demand from clinicians, payors and reimbursement authorities for robust RCT data, this publication places Symphony among a small group of CAMPs with Level I effectiveness data, strengthening its differentiation and commercial value proposition.”

The full study, A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People with Diabetes: A Randomized Controlled Trial, is available at https://pubmed.ncbi.nlm.nih.gov/42823610/.

About Symphony™
Symphony is AROA’s Cellular, Acellular and Matrix-like Product (CAMP, or “skin substitute”), combining AROA ECM™ with high molecular weight hyaluronic acid (HMWHA). It is designed to treat hard-to-heal wounds such as DFUs and venous leg ulcers.

HMWHA is a naturally occurring polymer with anti-inflammatory properties and the ability to retain approximately 1,000 times its weight in water, making it well suited to chronic wounds with persistent inflammation and moisture imbalance.

While CAMPs are commonly used to treat DFUs, AROA understands Symphony is the only commercially available product incorporating HMWHA.

About Aroa Biosurgery
Aroa Biosurgery Limited (ASX: ARX) is a New Zealand-based soft tissue regeneration company developing and commercializing products to improve healing in complex wounds and soft tissue reconstruction.