27.6 C
Vientiane
Saturday, June 21, 2025
spot_img
Home Blog Page 373

Yatsen Filed 2024 Annual Report on Form 20-F

GUANGZHOU, China, April 22, 2025 /PRNewswire/ — Yatsen Holding Limited (“Yatsen” or the “Company”) (NYSE: YSG), a leading China-based beauty group, today announced that the Company has filed its annual report on Form 20-F for the fiscal year ended December 31, 2024 with the U.S. Securities and Exchange Commission (“SEC”) on April 22, 2025.

The annual report is available on the Company’s investor relations website at ir.yatsenglobal.com and on the SEC’s website at https://www.sec.gov/. The Company will provide hard copies of the annual report, free of charge, to its shareholders and ADS holders upon written request. Requests should be directed to Investor Relations Department, Yatsen Holding Limited, Floor 39, Poly Development Plaza, No. 832 Yue Jiang Zhong Road Haizhu District, Guangzhou 510335, People’s Republic of China.

About Yatsen Holding Limited

Yatsen Holding Limited (NYSE: YSG) is a leading China-based beauty group with the mission of creating an exciting new journey of beauty discovery for consumers around the world. Founded in 2016, the Company has launched and acquired numerous color cosmetics and skincare brands including Perfect Diary, Little Ondine, Pink Bear, Galénic, DR.WU (its mainland China business), Eve Lom and EANTiM. The Company’s flagship brand, Perfect Diary, is one of the leading color cosmetics brands in China in terms of retail sales value. The Company primarily reaches and engages with customers directly both online and offline, with expansive presence across all major e-commerce, social and content platforms in China.

For more information, please visit http://ir.yatsenglobal.com/.

For investor and media inquiries, please contact:

In China:

Yatsen Holding Limited
Investor Relations
E-mail: ir@yatsenglobal.com 

Piacente Financial Communications
Hui Fan
Tel: +86-10-6508-0677
E-mail: yatsen@thepiacentegroup.com 

In the United States:

Piacente Financial Communications
Brandi Piacente
Tel: +1-212-481-2050
E-mail: yatsen@thepiacentegroup.com 

 

Gaotu Techedu Files Its Annual Report on Form 20-F

BEIJING, April 22, 2025 /PRNewswire/ — Gaotu Techedu Inc. (NYSE: GOTU) (“Gaotu” or the “Company”), a technology-driven education company and online large-class tutoring service provider in China, today filed its annual report on Form 20-F for the fiscal year ended December 31, 2024 with the U.S. Securities and Exchange Commission. The annual report on Form 20-F can be accessed on the Company’s investor relations website at https://ir.gaotu.cn/.

The Company will provide a hard copy of its annual report containing the audited consolidated financial statements, free of charge, to its shareholders and ADS holders upon request. Requests should be directed to Investor Relations Department, Gaotu Techedu Inc., 5F, Gientech Building, 17 East Zone, 10 Xibeiwang East Road, Haidian District, Beijing 100193, People’s Republic of China.

About Gaotu Techedu Inc.

Gaotu is a technology-driven education company and online large-class tutoring service provider in China. The Company offers learning services and educational content & digitalized learning products. Gaotu adopts an online live large-class format to deliver its courses, which the Company believes is the most effective and scalable model to disseminate scarce high-quality teaching resources to aspiring students in China. Big data analytics permeates every aspect of the Company’s business and facilitates the application of the latest technology to improve teaching delivery, student learning experience, and operational efficiency.

For further information, please contact:

Gaotu Techedu Inc.
Investor Relations
E-mail: ir@gaotu.com 

Piacente Financial Communications
Brandi Piacente
Tel: +1 212 481-2050
Jenny Cai
Tel: +86 10 6508-0677
Email: Gaotu@tpg-ir.com

Phra Man Buddha Now Open for Merit-Making Activities at Wat Xieng Thong in Luang Prabang

Phra Man Procession at Xieng Thong Temple. (Photo: Tourism Luang Prabang)

Xieng Thong Temple in Luang Prabang has officially opened the Ho Phra Man shrine, inviting locals and tourists to pay their respects to the sacred Phra Man Buddha statue as part of the annual Lao New Year (Pi Mai) tradition.

Cost and Performance Advantages of Replacing HBase with TencentDB TDSQL TDStore Engine in Historical Data Scenarios

SHENZHEN, China, April 22, 2025 /PRNewswire/ — HBase has long been a preferred solution for large-scale data storage due to its scalability, high availability, and cost-effectiveness on commodity hardware. However, evolving business demands—such as the need for structured data management, real-time analytics, and cost optimization—have exposed limitations in HBase’s functionality. TencentDB TDSQL  (TDStore Engine) addresses these gaps with a NewSQL architecture, offering MySQL 8.0 compatibility, cloud-native elasticity, and advanced compression, making it a superior alternative for historical data storage.

Key Limitations of HBase

  1. Operational Complexity: HBase’s reliance on multiple components (e.g., Hadoop ecosystem tools) complicates deployment and maintenance. Declining community support further exacerbates these challenges.
  2. Lack of Secondary Indexes: Queries require sequential access to index and primary tables, increasing latency (e.g., 150 ms average query time).
  3. Transactional Constraints: HBase only guarantees single-row atomicity, complicating consistency between primary and index tables.
  4. High Disaster Recovery Costs: Dual-cluster setups (5–6 replicas) for cross-AZ redundancy inflate storage costs.
  5. Compression Limitations: Default Snappy compression offers suboptimal efficiency, while upgrading to ZSTD risks instability.

Advantages of TDSQL TDStore Engine

  1. Cost Efficiency
    a.   Storage Optimization: TDStore’s LZ4+ZSTD compression achieves a 47% reduction in single-replica storage size compared to HBase’s Snappy. Combined with reduced replica requirements (one TDStore cluster replaces dual HBase clusters), overall costs drop significantly.
    b.   Native Compression: Transparent data compression minimizes storage footprints without compromising query performance.
  2. Performance Improvements
    a.   Latency Reduction: By eliminating redundant query steps (e.g., secondary index lookups), TDStore cuts average query latency from 150 ms to 37 ms.
    b.   High Throughput: A multi-master architecture supports horizontal scaling, handling millions of QPS for real-time transactions.
  3. Enhanced Data Governance
    a.   Structured Schema: Unlike HBase’s schema-less KV design, TDStore enforces predefined columns and data types, preventing invalid data ingestion and reducing post-validation efforts.
    b.   Unified SQL Access: Native MySQL compatibility simplifies integration with existing systems, avoiding middleware like Phoenix.
  4. Operational Simplicity
    a.   Cloud-Native Elasticity: Containerized management enables seamless scaling and upgrades without downtime.
    b.   Online DDL Support: Schema changes (e.g., adding columns or indexes) execute natively without external tools, ensuring uninterrupted operations.

Case Study: Tencent Financial Services

In a payment records system, migrating from HBase to TDStore reduced storage costs by 47% and query latency by 75%. The elimination of dual-cluster redundancy and streamlined SQL access further enhanced operational efficiency.

Conclusion

TencentDB TDSQL TDStore Engine demonstrates clear superiority over HBase in historical data scenarios, balancing cost, performance, and manageability. Its cloud-native design, MySQL compatibility, and advanced compression align with modern requirements for scalable, low-latency data management. As Tencent continues refining TDStore, it aims to solidify its role in enterprise-grade data solutions.

#TencentDB #TDSQL #Tencent Cloud Big Data

CK Life Sciences’ Investigational Cancer Vaccines Deliver Promising Results – New Preclinical Study Data to be Presented at the 2025 American Association for Cancer Research (AACR) Annual Meeting


HONG KONG SAR – Media OutReach Newswire – 22 April 2025 – CK Life Sciences Int’l., (Holdings) Inc. (“the Company”) announced that the Company will be presenting new data from its cancer vaccine research pipeline at the 2025 American Association for Cancer Research (AACR) Annual Meeting in Chicago, USA.

The AACR Annual Meeting is a gathering central to the global cancer research community, bringing together scientists, clinicians, other healthcare professionals, survivors, patients and advocates every year to share the latest breakthroughs and developments in cancer science and medicine. Last year, the 2024 Annual Meeting attracted 23,000 in-person attendees and 6,700 online participants from 78 countries.

In recent years, CK Life Sciences has regularly participated at the AACR Annual Meeting. The 2025 Annual Meeting will be held from 25-30 April. At the event, CK Life Sciences will exhibit posters highlighting data from preclinical studies of investigational cancer vaccines programs targeting (i) PRAME (Preferentially Expressed Antigen in Melanoma), (ii) PD-L1 (programmed cell death ligand 1), (iii) B7-H3 (B7 homolog 3) and (iv) Claudin 6 proteins, respectively.

PRAME is a protein highly expressed in several cancers, including melanoma, liver cancer and leukemia.

PD-L1 is one of the most important immune checkpoint proteins that is highly expressed in cancer cells to block T cell activation in the tumour microenvironment.

B7-H3 is another immune checkpoint protein that modulates T cell responses and is often overexpressed in cancer.

Claudin 6 is a tight junction protein that regulates epithelial barrier integrity and is overexpressed in cancers like breast cancer, lung cancer and endometrial cancer, where it is associated with tumour progression and metastasis.

In addition, CK Life Sciences will be co-presenting with our research collaborator two posters showcasing our Artificial Intelligence (AI)-empowered platform for designing cancer vaccines.

“CK Life Sciences is pleased with the preclinical efficacy results of its investigational cancer vaccines targeting PRAME, PD-L1, B7-H3 and Claudin 6 proteins, and we hope to further advance the research & development of these and other cancer vaccines. We are also excited about the progress achieved in our efforts to develop an AI platform aimed at designing cancer vaccines that are more likely to be immunogenic and clinically effective,” said Melvin Toh, Vice President and Chief Scientific Officer at CK Life Sciences.

Dr. Toh continued, “CK Life Sciences is determined to accelerate its R&D to benefit cancer patients. Currently, a number of therapeutic cancer vaccines are in clinical and discovery/preclinical research stages. Amongst them, seviprotimut-L, a cancer vaccine already in the final research stage, is being tested for the adjuvant treatment of stage IIB or IIC melanoma following definitive surgical resection.

DETAILS ON POSTER PRESENTATIONS:

  • Abstract 853: PDL1-PRAME dual antigen cancer vaccine inhibits melanoma growth in syngeneic mouse model and induces antigen-specific immune responses

Authors: Kin-Tak Chan, Hsin-Wei Chen, Pi-Hui Liang, You-Yu Lin, Tristan Zhang, Melvin Toh

Session Category: Clinical Research
Session Title: Vaccines and Cell Therapies
Session Date and Time: 4/27/2025 2:00 PM – 5:00 PM
Location: Poster Section 35
Poster Board Number: 9

  • Abstract 3533: Claudin 6 vaccines effectively inhibit tumor growth in a syngeneic mouse colon cancer model

Authors: Na Wang, Melvin Toh, Hong Wang

Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 9

  • Abstract 3536: Synergistic effects of combined PD-L1 and B7-H3 fusion protein vaccination in a mouse model of pancreatic cancer
Authors: Kenneth Nansheng Lin, Melvin Toh, Hong Wang
Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 12

  • Abstract 3538: The development of neoantigen-derived peptide vaccine driven by AI epitope design and computer assisted epitope enhancement

Authors: Chi Han Samson Li, Hong Wang, Kin Tak Chan, Genwei Zhang, Jiewen Du, Lipeng Lai, Melvin Toh

Session Category: Immunology
Session Title: Vaccines, In Situ Vaccines, and Vaccine Combinations
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 39
Poster Board Number: 14

  • Abstract 3649: Artificial intelligence accelerates shared neoantigen peptide cancer vaccine development

Authors: Genwei Zhang, Jiewen Du, Xiangrui Gao, Zhenghui Wang, Qingxia Zhang, Tongren Liu, Dong Chen, Chi Han Samson Li, Kin Tak Chan, Hong Wang, Melvin Toh, Lipeng Lai

Session Category: Bioinformatics/ Computational Biology/ Systems Biology/ Convergent Science
Session Title: Artificial Intelligence and Machine Learning for Therapeutic Election and Discovery
Session Date and Time: 4/28/2025 2:00 PM – 5:00 PM
Location: Poster Section 45
Poster Board Number: 11

The full abstracts are available in the AACR Online Itinerary Planner, which can be accessed at: https://www.abstractsonline.com/pp8/#!/20273


DISCLAIMER
This press release may contain forward-looking statements regarding the Group’s research and development projects which may involve risks and uncertainties. Actual results may differ materially from expectations discussed in such forward-looking statements.
All information in this press release is for general reference only and is not intended as investment advice or medical advice. CK Life Sciences Int’l., (Holdings) Inc. does not warrant or represent, express or implied, as to the accuracy, completeness or updated status of such information. No liability will be accepted for any loss or damage howsoever arising from or in reliance upon such information.
Copyright ©2025 CK Life Sciences Int’l., (Holdings) Inc. All rights reserved.

Hashtag: #CKLifeSciences #CancerVaccines #R&D #Pharmaceutical #AmericanAssociationforCancerResearch #AACR #PRAME #PD-L1 #B7-H3 #Claudin6Proteins #Melanoma #AI

The issuer is solely responsible for the content of this announcement.

DXC Announces AI Workbench; Ferrovial to Serve as Anchor Client

DXC’s AI Workbench combines industry and AI expertise to scale outcomes for global customers

ASHBURN, Va., April 22, 2025 /PRNewswire/ — DXC Technology (NYSE: DXC), a leading Fortune 500 global technology services provider, introduced today DXC AI Workbench, a generative AI offering which combines consulting, engineering, and secure enterprise services to help businesses worldwide integrate and scale responsible AI into their operations. Ferrovial (NASDAQ: FER), a leading global infrastructure company, is already using AI Workbench to enhance operations for its 24,000 employees. With more than 30 AI agents making real-time decisions, Ferrovial is improving efficiency and safety measures across its business.

 

DXC Announces AI Workbench with Ferrovial

DXC helps clients across industries find scalable solutions to meet their unique challenges, so they can move fast. With its new AI Workbench offering, DXC is delivering a pre-built scalable solution with necessary safeguards and governance for secure deployment.

“AI isn’t a plug-and-play solution—leveraging GenAI securely and in compliance with regulations requires human due diligence, customization, and the right skill sets,” said Howard Boville, President, DXC Consulting & Engineering Services – Powered by AI. “We’re helping clients, such as Ferrovial, build and implement AI solutions throughout their operations to drive outcomes at scale and unlock opportunities to innovate.

“By working with DXC, we’ve unlocked new levels of operational efficiency and reduced risks,” said Dimitris Bountolos, Chief Information and Innovation Officer (CIIO) of Ferrovial. “The ability to integrate AI into our core business processes has revolutionized how we reduce operational costs, manage knowledge, and make decisions, providing us with a competitive edge in the industry.”

Ferrovial is leveraging DXC’s industry and AI expertise to build and deploy AI-powered solutions across a wide range of business functions. With over 30 specialized AI agents deployed on a cloud-based AI platform running on Microsoft Azure, Ferrovial is now able to optimize field operations, elevate safety measures, manage business knowledge, analyze competition, and assess regulatory impacts. The platform’s seamless integration with Ferrovial’s back-office systems, such as Workday, ServiceNow, Microsoft Teams, and Ferrovial’s custom apps, has accelerated automation and data-driven decision-making across its global operations.

With deep industry expertise, DXC is uniquely positioned to help organizations adopt and scale AI solutions to drive real business outcomes.

For more on DXC Consulting & Engineering Services, visit here

About DXC Technology
DXC Technology (NYSE: DXC) helps global companies run their mission-critical systems and operations while modernizing IT, optimizing data architectures, and ensuring security and scalability across public, private, and hybrid clouds. The world’s largest companies and public sector organizations trust DXC to deploy services to drive new levels of performance, competitiveness, and customer experience across their IT estates. Learn more about how we deliver excellence for our customers and colleagues at DXC.com.

About Ferrovial
Ferrovial is one of the world’s leading infrastructure companies. The Company operates in more than 15 countries and has a workforce of over 25,000 worldwide. Ferrovial is triple listed on Euronext Amsterdam, the Spanish Stock Exchanges and Nasdaq and is a member of Spain’s blue-chip IBEX 35 index. It is also included in globally recognised sustainability indices such as the Dow Jones Best in Class Index (former Dow Jones Sustainability Index), and all its operations are conducted in compliance with the principles of the UN Global Compact, which the Company adopted in 2002.

Video – https://mma.prnasia.com/media2/2667818/DXC_Technology_Company_DXC_Announces_AI_Workbench__Ferrovial_to.mp4

Hisense Launches New ULED MiniLED U8 Series TV, Elevating Home Entertainment to Cinematic Heights

QINGDAO, China, April 22, 2025 /PRNewswire/ — Hisense, a global leader in consumer electronics and home appliances, today launched its groundbreaking ULED MiniLED U8 Series TV. As the No. 1 maker of 100-inch+ TVs globally, Hisense continues to lead the large-screen revolution, bringing cinematic scale and premium performance into the living room. Designed for cinephiles, gamers, and sports fans, the U8 Series TV redefines home entertainment. With advanced Mini-LED PRO and the Hi-View AI Engine PRO, every frame bursts with vibrant color, precise detail, and striking contrast — from the truest blacks to brilliant highlights.

Hisense U8 Series TV
Hisense U8 Series TV

The U8 Series TV sets a new benchmark for picture quality. Mini-LED PRO technology delivers unparalleled brightness and deep, true darkness. Meticulous backlight control renders each nuance with pristine accuracy, whether you’re watching high-octane sports or an intimate film scene. The result is a display that captivates with dynamic range and lifelike clarity. Powered by the Hi-View AI Engine PRO with AI Picture, AI Sound, AI Scenario, and AI Energy—the U8 Series TV smartly optimizes visuals, audio, scene settings, and energy use for an enhanced experience. Engineered for dynamic content, the U8 Series TV offers a native 165Hz refresh rate and Variable Refresh Rate (VRR), ensuring ultra-smooth, lag-free visuals — ideal for competitive gaming and fast-paced action.

Hisense tackles diverse viewing conditions with Anti-Reflection PRO technology, reducing glare in both bright and dim settings for a consistently clear display. The QLED Colour system, validated by Pantone standards, delivers over a billion true-to-life shades, turning every scene into a visual masterpiece.

In addition to its visual prowess, the U8 Series TV offers a compelling audio experience with its advanced 4.1.2 multi-channel sound system. Integrating side speakers, rear subwoofers, and upward-firing units, the U8 Series TV creates an immersive soundscape that perfectly complements its visuals. Every sound is rendered with exceptional clarity, while Devialet certification—configurable via OTA (over-the-air) updates—ensures ongoing, state-of-the-art performance.

Smart connectivity is seamlessly integrated, allowing users to access a wide range of content via popular streaming platforms. With voice control support through “Hey Google/VIDAA,” navigation becomes intuitive, placing a world of entertainment and smart home functionality at your fingertips.

The ULED MiniLED U8 Series TV sets a new standard in home entertainment by combining state-of-the-art technology with elegant design. It is a testament to Hisense’s commitment to innovation and excellence, offering a unified experience where visionary visuals and immersive audio converge to redefine what’s possible in the living room.

As the first official partner of the FIFA Club World Cup 2025™, Hisense brings the U8 Series TV to homes worldwide—delivering cinema-level picture and sound that make every football match, game, or movie feel larger than life, right from your couch.

The Hisense U8 Series TV is now available worldwide, with specific release dates determined by local channels. It is offered in six sizes—55, 65, 75, 85, and 100 inches—to perfectly suit any home environment. (*Availability of size options may vary by region.)

About Hisense

Hisense, founded in 1969, is a globally recognized leader in home appliances and consumer electronics with operations in over 160 countries, specializing in delivering high-quality multimedia products, home appliances, and intelligent IT solutions. According to Omdia, Hisense ranks No. 2 worldwide in total TV shipments (2022-2024) and No. 1 globally in the 100-inch and over TV segment (2023-2024). As the first official partner of the FIFA Club World Cup 2025™, Hisense is committed to global sports partnerships as a way to connect with audiences worldwide.

HUYA Inc. to Report First Quarter 2025 Financial Results on Tuesday, May 13, 2025

-Earnings Webinar Scheduled for 8:00 a.m. ET on May 13, 2025

GUANGZHOU, China, April 22, 2025 /PRNewswire/ — HUYA Inc. (“Huya” or the “Company”) (NYSE: HUYA), a leading game live streaming platform in China, today announced that it will report its first quarter 2025 unaudited financial results on Tuesday, May 13, 2025, before the open of U.S. markets.

The Company’s management will host a Tencent Meeting Webinar at 8:00 a.m. U.S. Eastern Time on May 13, 2025 (8:00 p.m. Beijing/Hong Kong time on May 13, 2025), to review and discuss the Company’s business and financial performance.

For participants who wish to join the webinar, please complete the online registration in advance using the links provided below. Upon registration, participants will receive an email with webinar access information, including meeting ID, meeting link, dial-in numbers, and a unique attendee ID to join the webinar.

Participant Online Registration

A live webcast of the webinar will be accessible at https://ir.huya.com, and a replay of the webcast will be available following the session.

[1] For the purpose of this announcement only, Chinese Mainland excludes the Hong Kong Special Administrative Region, the Macao Special Administrative Region of the People’s Republic of China, and Taiwan.

About HUYA Inc.

HUYA Inc. is a leading game live streaming platform in China. As a technology-driven company, Huya offers rich and dynamic content across games, e-sports, and other entertainment genres where it has cultivated a large, highly engaged, interactive, immersive community of game enthusiasts. Building on its success in game live streaming and through close collaboration with game companies, e-sports tournament organizers, broadcasters and talent agencies, Huya is expanding its presence in the game industry, both domestically and internationally. By providing more innovative game-related services, the Company is committed to meeting the evolving needs of game enthusiasts, content creators, and industry partners.

For more information, please visit: https://ir.huya.com.

For investor and media inquiries, please contact: 

In China:

HUYA Inc.
Investor Relations
Tel: +86-20-2290-7829
E-mail: ir@huya.com

Piacente Financial Communications
Jenny Cai
Tel: +86-10-6508-0677
E-mail: huya@tpg-ir.com

In the United States:

Piacente Financial Communications
Brandi Piacente
Tel: +1-212-481-2050
E-mail: huya@tpg-ir.com