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Asian Hardware Online Exhibition 2025 Grand Opening – A Premier B2B Hardware Event


TAIPEI, TAIWAN – Media OutReach Newswire – 25 February 2025 – The Asian Hardware Online Exhibition 2025 (AsianHardware 2025) is set to redefine the hardware products industry with its innovative hybrid format, seamlessly blending virtual and physical elements. Scheduled to run from February 25, 2025, to May 31, 2025, the exhibition provides an unparalleled opportunity for Asian suppliers, importers, and exporters to connect, collaborate, and showcase their brands on a global scale.

Asian Hardware Online Exhibition 2025 Grand Opening – A Premier B2B Hardware Event

Jointly organized by AsianNet and TradeAsia (www.e-tradeasia.com), AsianHardware 2025 has delivered exceptional results since its inception in 2022, attracting international buyers and generating significant business opportunities. The 2025 edition promises to be even more expansive, with a three-month exhibition period strategically aligned with major international events, including Expo Nacional Ferretera 2025 (Mexico City), National Hardware Show, Fastener Fair Global 2025 and MosBuild – Buildex. This alignment creates a synergistic platform for global buyers, facilitating convenient comparisons and streamlined purchasing experiences.

AsianHardware 2025 has already secured the participation of numerous esteemed Taiwanese suppliers, including industry leaders such as ASCCO INTERNATIONAL, SCANO INDUSTRIAL, KINGDOM ABRASIVE, RAI ANG ENTERPRISE, CHUN CHENG PLASTICS, MASTER RESOURCE INDUSTRIES, CASEMATE PLASTICS INDUSTRIES, A-BELT-LIN INDUSTRIAL, YI CHI HSIUNG, OAV EQUIPMENT & TOOLS, CHU-SHIANG INDUSTRIAL, FLYWELL INTERNATIONAL, YAU YOUNG AUTO PARTS and LEAVEN ENTERPRISE. These exhibitors will present their latest innovations across a diverse range of categories, including general hardware, door & window hardware, furniture hardware, cabinet hardware, bathroom hardware, plumbing hardware, sanitary ware & plumbing, bathroom & fitting, lock & safe, hand tool, power tool & accessory, pneumatic & air tool, hydraulic tool, measuring & gauging tool, building apparatus, building material, construction tool, outdoor furniture, light and lighting, tool part & accessory, screw, fastener and nail, paint & coating, adhesive & sealant, battery, wire, cable & cable assembly, agricultural & gardening tool, vehicle equipment & tool, auto accessories, general industrial equipment, machine tool, metal processing machinery, industrial supporting machinery, logistic supply, workplace safety products, fire & safety products, and environmental equipment. With thousands of innovative hardware products, along with practical accessories and solutions on display, AsianHardware 2025 promises a comprehensive, engaging, and highly focused experience tailored to the needs of buyers and professionals in the hardware supplies industry.

AsianHardware 2025 Online Exhibition:
https://www.etradeasia.com/online-show/37/Asian-Hardware-Online-Exhibition-2025.html

In response to the evolving landscape of international trade, AsianHardware 2025 offers an array of virtual solutions to ensure accessibility and global reach. These include dedicated exhibitor pages, electronic catalogs, and immersive virtual exhibition halls—all seamlessly integrated with TradeAsia. Buyers can explore products, initiate inquiries, and engage in procurement discussions in real time, eliminating geographical barriers and travel constraints.

Founded in 1997, TradeAsia (www.e-tradeasia.com) is a premier B2B international trade platform, serving as a vital link between global buyers and suppliers. With millions of registered members, over 600,000 suppliers, and a vast catalog of products, TradeAsia is a trusted resource for businesses seeking to expand their international presence. By fostering collaborations with hundreds of trading entities worldwide, TradeAsia amplifies visibility and marketing impact for its members, providing a competitive edge in the global market.

With its extended duration and comprehensive platform, AsianHardware 2025 is poised to be the most influential event for the hardware products industry in Asia. Don’t miss this opportunity to connect with leading suppliers and explore the latest innovations.Hashtag: #TradeAsia

The issuer is solely responsible for the content of this announcement.

Musk, memecoins, and the crypto market: Octa broker’s expert view


KUALA LUMPUR, MALAYSIA – Media OutReach Newswire – 25 February 2025 – Over the past few years, the strategic endorsements, enigmatic tweets, and business manoeuvres of Elon Musk have caused shock waves in the cryptocurrency market with wild price fluctuations. Today, he is creating a native cryptocurrency on the X platform under the temporary name, X Money.

Source: Shutterstock
Source: Shutterstock

When and if it happens, the project can turn X (ex. Twitter) into a complete financial system, making Musk an overnight competitor for traditional banking systems as well as traditional crypto payment systems. Others believe this could be an attempt by Musk to create a decentralised alternative to PayPal and traditional fintech platforms, counting on X’s massive user base to drive its uptake. Kar Yong Ang, a financial market analyst at Octa Broker, elaborates: Will X Money be the disruptive force that reshapes digital finance, or just another speculative experiment.

The Musk factor
When Elon Musk set his sights on Dogecoin, the market took notice. His influence became undeniable when a single tweet sent the price soaring. In December 2020, a seemingly casual tweet, ‘One word: Doge’, triggered a 20% price surge within hours.

By May 2021, following Musk’s Saturday Night Live appearance, Dogecoin had skyrocketed to $0.73, marking an astronomical rise of over 10,000% from the previous year. However, the euphoria was short-lived, as Musk jokingly referred to Dogecoin as a ‘hustle’ on national television, prompting an immediate crash. The cycle repeated as Musk continued to tease integrations with Tesla, Twitter (now X), and even SpaceX. Each hint of Dogecoin adoption sent waves through the market, illustrating an unprecedented case of social media-driven price manipulation.

Market impact analysis: price movement correlation
A close look at the price movement of Dogecoin shows an unavoidable connection between Musk’s interest and its price. Between December 2020 and May 2021, Dogecoin pumped from $0.003 to its all-time high, over 24,000%. The next year, as Musk’s attention turned elsewhere, it fell by 90%, showing its speculative volatility. When Musk floated the idea of accepting Dogecoin payments on Twitter in early 2023, its price jumped 30% in a day, indicating his influence had not diminished.

The broader crypto market, on the other hand, tended to mirror Dogecoin’s peaks and valleys, highlighting Musk’s broader sway. When Tesla announced that it would no longer accept Bitcoin due to environmental concerns, the entire market tanked, with Dogecoin shedding 40% of its value in a matter of days.

Dogecoin is not the only Musk-linked token to experience extreme price swings. The rise of Musk-inspired coins, such as ElonCoin, MuskSwap, and even parody tokens like Dogelon Mars, has followed a similar trajectory. In 2021, Dogelon Mars ($ELON) surged 4,000% in under a month, fueled by speculation that Musk would support it. Similarly, Musk’s offhand social media posts have caused ElonCoin to spike over 600% in a single week before rapidly retracing. Musk’s mere association with crypto—whether intentional or not—creates instant market distortions.

Legal and regulatory implications
Musk’s market-shaping tweets have not gone unnoticed by regulators. In 2022, a class-action lawsuit alleged that he had engaged in deliberate market manipulation, artificially inflating Dogecoin’s price before selling off at a profit. While Musk dismissed the case as frivolous, regulatory bodies, particularly the SEC, have intensified their scrutiny of influencer-driven market movements. ‘If the lawsuit succeeds, it could set a precedent for greater oversight in cryptocurrency markets, potentially curbing speculative hype cycles‘, Kar Yong Ang explains. ‘Such intervention could reshape the industry, making it less susceptible to manipulation but also reducing the high-risk, high-reward nature that attracts many traders’, concludes the expert.

Future Outlook: Market Predictions
The broader ‘Musk Effect’ continues to fuel speculative hysteria in the crypto markets. The effect is not limited to Musk’s own initiatives: coins tied to his public persona, family, and even unrelated memes tend to experience parabolic price appreciation.

Most recently, Trump and Melania-themed memecoins have introduced a fresh wave of speculative trading. Meanwhile, Musk himself still indirectly impacts the memecoin universe. His recent internet antics, such as rebranding himself ‘Harry Bōlz’ on X, coincided with a $28 million trading volume spike in niche tokens, demonstrating how market volatility triggers can stem from seemingly trivial events.

Investment considerations and risk assessment
With Musk potentially entering the cryptocurrency market directly through X Money, the landscape could shift dramatically. Unlike Dogecoin, which remains largely speculative and community-driven, a Musk-backed financial token could introduce tangible use cases, particularly within X’s expanding payment ecosystem.

Key risk factors for investors include:

  • Regulatory uncertainty: authorities are closely monitoring Musk’s financial ventures, and any potential legal challenges could impact X Money’s development.
  • Market volatility: If history is any indication, Musk’s crypto projects tend to cause significant market swings, benefiting early adopters but posing risks for those entering peak hype cycles.
  • Adoption challenges: For X Money to succeed, it must offer compelling advantages over existing payment solutions like PayPal and USDC-backed stablecoins. Its adoption will depend on how well it integrates with financial services within the X platform.

Despite these risks, the possibility of Musk disrupting the digital payments space cannot be overlooked. If X Money launches successfully, it could become a dominant force in fintech, further cementing Musk’s influence over global markets.

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Disclaimer: Trading involves risks and may not be suitable for all investors. Use your expertise wisely and evaluate all associated risks before making an investment decision.
Hashtag: #Octa

The issuer is solely responsible for the content of this announcement.

Octa

is an international CFD broker that has been providing online trading services worldwide since 2011. It offers commission-free access to financial markets and various services used by clients from 180 countries who have opened more than 52 million trading accounts. To help its clients reach their investment goals, Octa offers free educational webinars, articles, and analytical tools.

The company is involved in a comprehensive network of charitable and humanitarian initiatives, including the improvement of educational infrastructure and short-notice relief projects supporting local communities.

In the APAC region, Octa received the ‘Best Trading Platform Malaysia 2024’ and the ‘Most Reliable Broker Asia 2023’ awards from Brands and Business Magazine and International Global Forex Awards, respectively.

ADA and IPification Partner to Revolutionize Seamless Authentication for Digital Apps

SINGAPORE, Feb. 25, 2025 /PRNewswire/ — ADA, a leader in data and AI-driven digital transformation and all-in-one authentication solutions, and IPification, a pioneer in seamless mobile authentication, have announced their strategic partnership to drive next-generation authentication solutions for enterprises and digital applications.

By leveraging carrier API-based authentication, ADA and IPification will enable businesses to enhance security, streamline user experiences, and reduce fraud, all without compromising user privacy or convenience.

As part of this partnership, ADA will serve as a strategic go-to-market partner for IPification, ensuring seamless enterprise adoption and integration of authentication solutions. 

With a robust network across enterprises and mobile operators, ADA already provides a holistic approach to security, offering seamless carrier API-based authentication alongside multi-channel verification via SMS, WhatsApp, email, and other regional OTTs. This business and platform integration uniquely positions ADA to deliver a comprehensive authentication ecosystem that caters to the full spectrum of enterprise needs.

“ADA is committed to transforming digital experiences with the power of data, AI, and technology,” said Srinivas Gattamneni, CEO at ADA. “Our partnership with IPification marks a significant step in redefining authentication standards, enabling our partners to provide users with seamless, one-tap security that enhances both trust and engagement.”

IPification’s CEO Stefan Kostic added, “We are excited to collaborate with ADA, a company that shares our vision for frictionless security in the digital world. This partnership will empower enterprises with a best-in-class authentication solution that is both user-friendly and highly secure, eliminating the need for traditional passwords and one-time PINs.”

This joint business effort will drive enterprise adoption of carrier API-based authentication, ensuring organizations can meet the growing demand for secure and user-friendly authentication while maintaining compliance with evolving digital security standards.

For more information about this partnership, please visit adagobal.com and ipification.com.

About ADA
ADA is a leading provider of data and AI-driven solutions that transform businesses across digital, marketing, and commerce. With a strong presence in Asia and beyond, ADA empowers enterprises with advanced technology solutions to drive business growth, optimize customer experiences, and enhance digital transformation. For more information, visit www.adaglobal.com.

About IPification
IPification is building the backbone of mobile authentication of today and tomorrow. By verifying the phone number, SIM card, and device via IP address, IPification patented technology is enabling secure, passwordless, zero-tap compatible mobile user authentication, registration, transaction approval, and fraud prevention solutions for any mobile application. Readily available across numerous countries and regions, IPification is trusted by the leading telecom, technology, payment, and OTT companies.

For more information, please visit www.ipification.com

Medtronic Malaysia and Malaysian Society of Colorectal Surgeons sign MOU to enhance medical training and education programs

KUALA LUMPUR, Malaysia, Feb. 25, 2025 /PRNewswire/ — Medtronic plc, a global leader in healthcare technology, announced that Medtronic Malaysia and Malaysian Society of Colorectal Surgeons (MSCRS) have signed a Memorandum of Understanding (MoU) to jointly organize surgical workshops aimed at enhancing the skills of colorectal surgeons in Malaysia.

Dr Nurhashim Haron, Vice President of the Malaysian Society of Colorectal Surgeons, Dr Luqman Mazlan, President of the Malaysian Society of Colorectal Surgeons, Simon Yam, Country Director, Medtronic Malaysia, Sam Teoh, Senior Sales Field Manager, Medical Surgical, Medtronic Malaysia
Dr Nurhashim Haron, Vice President of the Malaysian Society of Colorectal Surgeons, Dr Luqman Mazlan, President of the Malaysian Society of Colorectal Surgeons, Simon Yam, Country Director, Medtronic Malaysia, Sam Teoh, Senior Sales Field Manager, Medical Surgical, Medtronic Malaysia

Through this collaboration, Medtronic Malaysia and MSCRS will partner with hospitals nationwide to organize surgical workshops tailored to the evolving needs of the medical community. These workshops will focus on advancing knowledge, improving surgical techniques, and ensuring optimal patient outcomes in colorectal care.

Paul Verhulst, vice president of Medtronic Southeast Asia, provided the following statement on the partnership: “This partnership underscores Medtronic’s commitment to advancing innovation and education in colorectal surgery. By working alongside MSCRS and hospitals in Malaysia, we aim to equip surgeons with the tools and techniques to enhance patient care. We strive to elevate surgical standards and drive better health outcomes through continuous learning and collaboration.”

Dr. Luqman Mazlan, president of the Malaysian Society of Colorectal Surgeons, commented: “This collaboration with Medtronic marks a significant milestone in advancing colorectal surgical education and training in Malaysia. Together, we will empower surgeons with the latest knowledge and techniques to address the growing complexities of colorectal health. This initiative will facilitate the exchange of expertise and best practices among healthcare professionals, ultimately benefiting patients nationwide.”

This partnership reflects Medtronic’s mission to support healthcare professionals through cutting-edge technologies, specialized training, and a strong network of expertise. By driving advancements in colorectal surgery, Medtronic Malaysia and MSCRS aim to enhance treatment standards and improve patient care across Malaysia.

About Medtronic

Bold thinking. Bolder actions. We are Medtronic. Medtronic plc, headquartered in Galway, Ireland, is the leading global healthcare technology company that boldly attacks the most challenging health problems facing humanity by searching out and finding solutions. Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people across more than 150 countries. Our technologies and therapies treat 70 health conditions and include cardiac devices, surgical robotics, insulin pumps, surgical tools, patient monitoring systems, and more. Powered by our diverse knowledge, insatiable curiosity, and desire to help all those who need it, we deliver innovative technologies that transform the lives of two people every second, every hour, every day. Expect more from us as we empower insight-driven care, experiences that put people first, and better outcomes for our world. In everything we do, we are engineering the extraordinary. For more information on Medtronic, visit www.Medtronic.com and follow on LinkedIn.

About Malaysian Society of Colorectal Surgeons

The Malaysian Society of Colorectal Surgeons was registered with the Registrar of Societies on March 30, 2005.  Since then, the Society has pursued its goals of promoting colorectal services, training and research through a multitude of activities, including scientific conferences, workshops, access to academic literature and postgraduate training funding, as well as advocating for colorectal surgeons. The Society also maintains strong collaborations with sister societies internationally, as well as related societies such as enterostomal therapy nurses’ associations, ostomy societies and colorectal cancer survivor support groups.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic’s periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.

NTU Singapore and Trinasolar to advance AI-powered smart energy storage solutions

SINGAPORE, Feb. 25, 2025 /PRNewswire/ — Nanyang Technological University, Singapore (NTU Singapore) and Trinasolar, a global smart photovoltaic (PV) and energy storage solutions provider, are collaborating to develop smart energy storage systems (ESS) to enhance efficiency, reliability, and economic viability in renewable energy applications.

(L-R) Executive Director of ERI@N Professor Madhavi Srinivasan and Executive President of Trinasolar, Helena Li signed a technology research collaboration agreement at Trinasolar’s Regional Headquarters in Singapore.
(L-R) Executive Director of ERI@N Professor Madhavi Srinivasan and Executive President of Trinasolar, Helena Li signed a technology research collaboration agreement at Trinasolar’s Regional Headquarters in Singapore.

As solar, wind, and hydrogen energy sources expand globally, energy storage technologies will play a critical role in ensuring power grid stability and optimising energy use.

Led by the Energy Research Institute @ NTU (ERI@N), the collaboration aims to develop AI-driven tools that can improve investment decisions, enhance system stability through intelligent energy forecasting, and deploy smart optimisation algorithms for diverse energy storage applications.

By combining Trinasolar’s expertise in PV and ESS technologies with NTU’s leading research in energy innovation, the collaboration seeks to address key challenges in smart energy storage through three strategic focus areas:

  1. Smart Investment Decision-making
  2. Ensuring System Stability with AI-Powered Forecasting
  3. Smart Optimisation Algorithms

NTU and Trinasolar formalised their partnership through a signing of a technology research collaboration agreement.

NTU Vice President (Industry) Professor Lam Khin Yong, highlighted the importance of academia-industry collaboration: “This partnership between NTU and Trinasolar reflects our commitment to advancing energy technologies that will support global efforts towards a low-carbon future. NTU has deep links with industry players and a strong track record in successful industry collaborations for renewable energy powergrids, thus enabling smooth commercialisation pathways for any intellectual property developed in our joint partnerships. By aligning cutting-edge research with industry needs, we want to develop impactful solutions that build a more sustainable and energy-resilient future.”

Helena Li, Executive President, Trinasolar emphasized the company’s commitment to research and development collaborations to create cutting-edge solar solutions: “As one of the global leading manufacturers of PV and ESS solutions with 30 world records under our belt, Trinasolar brings to the table its expertise in global solar-storage market trends and cutting-edge technologies. We are proud to collaborate with NTU, a top-tier research institution renowned for its academic excellence. This initiative aims to deliver tangible value to energy storage customers, including cost optimization, improved return on investment (ROI), and enhanced system reliability.”

Trinasolar and NTU Singapore are committed to deepening their collaboration in AI-powered energy storage applications and developing innovations to meet the evolving demands of the renewable energy sector.

Reducing Plastic Waste in North America: APP Group and Charta Global Paper Straws Lead Sustainable Packaging Efforts

JAKARTA, Indonesia, Feb. 25, 2025 /PRNewswire/ — Paper straws have become almost omnipresent in restaurants, bars, and fast food outlets as the hospitality industry has rushed to abandon plastic in response to consumer backlash. According to Data Intelligence, the drinking straw market in North America itself was valued at USD 3,208.44 million in 2022 and is expected to grow at a CAGR of 5.26% to reach USD 5,099.80 million by 2031.

Although plastic straw is still used by millions of people in the US, paper straw has been a common alternative to combat plastic waste, with the paper straw market significantly increasing over the years. U.S. citizens consider environmental sustainability important when making purchasing decisions. This shift in consumer sentiment is fostering greater demand for sustainable products like paper straws.

Despite paper straws having a positive impact on a greener environment, there are several challenges to using them compared to plastic straws. Some paper straws are found to contain PFA, which can harm the environment and tend to disintegrate after prolonged exposure to liquids, limiting their functional lifespan. To tackle these challenges, APP Group through its strategic partnership with Charta Global and Foopak Bio Natura has released a biodegradable and compostable paper straw that has received a plastic-free certification from Flustix since 2021. These straws are more durable, having excellent water resistance and other advantages such as being microwaveable and freezer friendly.

“A cornerstone of our sustainability efforts is the production of recyclable and biodegradable packaging. Unlike traditional plastic options, our paper-based products are crafted from renewable resources and are easily recyclable or compostable, helping to alleviate landfill waste.” stated Kin Keung Christopher Wong, Senior Vice President and Global Business Unit Head Industrial White at APP Group.

Together with APP Group, Charta Global’s tested biodegradable paper products are in line with sustainability trends and, more importantly, the government’s green initiatives in the U.S. Charta Global offers an extensive line of plastic-free, compostable paperboard and flexible grades for foodservice packaging.

About APP Group

APP is a leading pulp, paper, and forestry company based in Indonesia, supplying high-quality tissue, packaging, and paper to over 150 countries. With operations in Indonesia and China, we prioritize sustainability, ethical practices, and the well-being of our employees, society, and the environment. Our Sustainability Roadmap Vision 2030, aligned with ESG principles, guides our efforts in environmental protection, community support, biodiversity preservation, and carbon neutrality.

 

Oregon State University President highlights AI, innovation, and global careers for Taiwanese students


TAIPEI, TAIWAN Media OutReach Newswire – 25 February 2025 – As Taiwan continues to rise as a global powerhouse in semiconductors, AI, and advanced computing, Oregon State University (OSU) President Professor Jayathi Y. Murthy has made a compelling case for Taiwanese students to pursue world-class education and global career opportunities at OSU.

The OSU delegation with alumni and newly admitted students in Taipei.
The OSU delegation with alumni and newly admitted students in Taipei.

Addressing OSU alumni, newly admitted students, and their families at an exclusive event organized by the OSU Foundation, Murthy emphasized OSU’s leadership in AI, robotics, semiconductors, and sustainability research, making it an ideal destination for Taiwanese students seeking world-class research opportunities and career prospects.

“We provide the research environment, industry connections, and global opportunities to prepare OSU students to play a leading role in shaping the future of technology and innovation,” said Murthy.

Founded in 1868, OSU is a premier Tier 1 research university, ranked among the top 1.4% of higher education institutions globally. With US$422 million in annual research expenditures and a goal to double that by 2030, OSU remains at the forefront of AI, advanced computing, semiconductors, and engineering research. It hosts the largest Computer Science program in the U.S. and world-renowned programs in engineering, robotics, AI, oceanography, and sustainability.

Home to nearly 38,000 students from over 100 countries, OSU has a growing international student population, including more than 230 students from Taiwan.

Murthy highlighted OSU’s interdisciplinary approach to tackling global challenges, stating: “Our faculty are at the forefront of research in AI and robotics, climate science, clean energy and biotechnology – areas that will define the future of technology and sustainability worldwide.”

OSU’s impact in AI, advanced computing, semiconductors and robotics is underscored by its partnerships with global tech leaders, such as Google, Intel, NVIDIA, Amazon, and Tesla.

Notably, NVIDIA Founder and CEO Jen-Hsun Huang, an OSU alumnus, and his wife Lori Mills Huang have made a transformative US$50 million philanthropic investment in the Jen-Hsun and Lori Mills Huang Collaborative Innovation Complex at OSU. Set to open in 2026, this state-of-the-art facility will house one of the most powerful supercomputers in the United States, supporting research in AI, climate science, sustainability, and beyond.

“The Huang Collaborative Innovation Complex will be a game-changer for AI and climate science research,” Murthy noted. “It will empower OSU students and faculty to push the boundaries of innovation.”

The event celebrated OSU alumni in Taiwan as well as newly admitted Taiwanese students who will soon embark on their academic journey at OSU. With parents in attendance, Murthy emphasized OSU’s student-centered approach, career-integrated education, and commitment to student success.

“Our priority is to provide every OSU student with a strong foundation for success,” she said. “From our ‘Beyond OSU’ career initiative to our strong industry connections, we are committed to equipping students with the skills, experience, and networks to thrive in their chosen fields.”

For more information, visit www.oregonstate.edu.
Hashtag: #studyabroad #OSU #internationalstudents #intled #Taiwan #AI #Robotics #technology


The issuer is solely responsible for the content of this announcement.

Akeso Highlights Collaboration Between Its Partner Summit Therapeutics and Pfizer to Explore Ivonescimab in Combination with Pfizer’s ADCs

HONG KONG, Feb. 25, 2025 /PRNewswire/ — Akeso, Inc. (9926.HK) (“Akeso” or the “Company”) today announced that its partner on ivonescimab, Summit Therapeutics Inc. (NASDAQ: SMMT) has entered into a clinical trial collaboration with Pfizer Inc. (NYSE: PFE) to evaluate ivonescimab, a novel, investigational PD-1 / VEGF bispecific antibody, in combination with several of Pfizer’s antibody drug conjugates (ADCs) across multiple solid tumor settings.

“Rapidly developing novel mechanisms that go beyond what is currently available to patients and physicians is what we believe will make the most significant impact for those facing the greatest challenges from cancer today,” noted Bob Duggan and Dr. Maky Zanganeh, Summit’s Co-CEOs. “As we seek to accelerate the development of our potentially transformative ivonescimab across non-small cell lung cancer and other solid tumor settings, this collaboration will allow us to quickly advance beyond our promising late-stage development plan to evaluate ivonescimab in combination with some of the most innovative ADCs from Pfizer.”

The goal of the collaboration is to evaluate ivonescimab, in combination with several unique Pfizer ADCs across multiple solid tumor settings to accelerate the advancement of potentially landscape-changing combinations, which seek to improve the standards of care for patients facing serious unmet needs. Each study intends to evaluate ivonescimab plus one of Pfizer’s vedotin ADCs in individual, distinct solid tumor settings to determine the safety profile and potential anti-tumor activity of the combinations.

“We are excited to partner with Summit Therapeutics to explore the clinical synergy of our therapies,” said Megan O’Meara, M.D., Head, Oncology Early Stage Development, Pfizer. “Together, we are advancing the exploration of our ADCs in rational, differentiated combinations with a bispecific antibody designed to address the unique complexities of tumor biology. This collaboration represents the next wave of investigational targeted combinations with the potential to transform treatment options for people living with cancer.”

Under the terms of the agreement, Summit will provide ivonescimab for use in the proposed studies, and Pfizer will be responsible for conducting the operations of the studies. The studies will be overseen by both Summit and Pfizer. Both parties retain their respective rights to their products. The studies combining ivonescimab with Pfizer’s vedotin ADCs are planned to begin in the middle of this year. Further details on the clinical trials will be announced at a later date by Summit.

About Ivonescimab (AK112/SMT112)

Ivonescimab is a novel global first-in-class PD-1/VEGF bi-specific immunotherapy drug independently developed by Akeso. Ivonescimab is known as SMT112 in Summit Therapeutics’s license territories, including the United States, Canada, Europe, Japan, Central America, South America, the Middle East and Africa. Ivonescimab was granted marketing approval by NMPA for the treatment of EGFR mutated locally advanced or metastatic non-squamous NSCLC patients who have progressed after EGFR TKI treatment. Currently, ivonescimab’s first indication has been approved in China, and Akeso is conducting 6 registrational trials versus anti-PD-1/L1 therapeutics. Akeso is also conducting multiple clinical trials of ivonescimab covering 17 indications including gastrointestinal cancer, hepatocellular carcinoma and colorectal cancer.

About Akeso
Akeso (HKEX: 9926.HK) is a leading biopharmaceutical company committed to the research, development, manufacturing and commercialization of the world’s first or best-in-class innovative biological medicines. Founded in 2012, the company has created a unique integrated R&D innovation system with the comprehensive end-to-end drug development platform (ACE Platform) and bi-specific antibody drug development technology (Tetrabody) as the core, a GMP-compliant manufacturing system and a commercialization system with an advanced operation mode, and has gradually developed into a globally competitive biopharmaceutical company focused on innovative solutions. With fully integrated multi-functional platform, Akeso is internally working on a robust pipeline of over 50 innovative assets in the fields of cancer, autoimmune disease, inflammation, metabolic disease and other major diseases. Among them, 23 candidates have entered clinical trials (including 11 bispecific/multispecific antibodies and bispecific antibody-drug conjugates). Additionally, 5 new drugs are commercially available, and 5 new drugs across 7 indications are currently under regulatory review for approval. Through efficient and breakthrough R&D innovation, Akeso always integrates superior global resources, develops the first-in-class and best-in-class new drugs, provides affordable therapeutic antibodies for patients worldwide, and continuously creates more commercial and social values to become a global leading biopharmaceutical enterprise.

For more information, please visit https://www.akesobio.com/en/about-us/corporate-profile/ and follow us on Linkedin, and X (formerly Twitter).