SHANGHAI, March 31, 2026 /PRNewswire/ — On 30 March, 2026, Abbisko Therapeutics Co., Ltd. (“Abbisko Therapeutics” hereafter, HKEX code: 02256.HK) announced that the U.S. Food and Drug Administration has cleared the Investigational New Drug (IND) application for ABSK061, a highly selective small-molecule FGFR2/3 inhibitor, for the treatment of children with achondroplasia (ACH). Coupled with the recent Rare Pediatric Disease Designation (RPDD) and Orphan Drug Designation (ODD) granted by the FDA, this will help Abbisko accelerate the overseas clinical development process for ABSK061.

ABSK061 is currently being evaluated in a Phase II clinical trial for ACH, and in December 2025, the study dosed its first patient in China. Preliminary data are expected to be reported in the second half of 2026. As an important part in the global development strategy for ABSK061, Abbisko plans to enroll US patients into the Phase II study to further evaluate safety, tolerability, and efficacy of ABSK061 for the treatment of ACH.

Achondroplasia is a rare autosomal genetic disorder that causes severe growth and developmental impairments. Research has shown that the pathogenesis of ACH is driven by aberrant activation of the fibroblast Growth Factor Receptor 3 (FGFR3) caused by FGFR3 gene mutations, which suppress normal endochondral ossification ^[1]. Targeted inhibitors offer the potential to deliver more precise and effective treatment options for ACH patients.

ABSK061, independently developed by Abbisko Therapeutics, is a highly potent and selective small-molecule FGFR2/3 inhibitor. It has demonstrated robust target inhibitory activity, favorable pharmacokinetic properties, and a promising safety profile in preclinical studies. Its oral administration offers significant advantages in terms of convenience and treatment compliance-particularly for pediatric patients—and positions ABSK061 as a potentially valuable therapeutic candidate for children and adolescents with ACH.

About ABSK061

ABSK061 is a novel, orally bioavailable, highly potent and selective small molecule inhibitor of FGFR2 and FGFR3 independently discovered and wholly-owned by Abbisko Therapeutics. It is the first FGFR2/3 inhibitor to enter clinical trials globally. First-generation pan-FGFR inhibitors demonstrated clinical efficacy in multiple tumors carrying FGFR2/3 variants and have steadily gained regulatory approval globally. However, the therapeutic window of pan-FGFRs and their clinical efficacy have been limited by side effects associated with FGFR1 inhibition. By reducing FGFR1 activity while maintaining potency against FGFR2 and FGFR3, ABSK061 is expected to achieve a wider therapeutic window with improved clinical efficacy as a new-generation of FGFR inhibitors. ABSK061 for the treatment of achondroplasia has received both Rare Pediatric Disease Designation (RPDD) and Orphan Drug Designation (ODD) from the U.S. Food and Drug Administration (FDA), and its Phase II clinical trial is currently ongoing.

MUMBAI, India, March 31, 2026 /PRNewswire/ — Tata Communications today redefined resilience for the global digital economy with the launch of IZO™ Data Centre* Dynamic Connectivity, a software-defined platform designed to transform how enterprises connect their Data Centres in an increasing AI driven and distributed world. 

In today’s digital economy, every enterprise depends on the ability to always be connected with an uninterrupted data flow. From financial transactions, IT-ITeS, Manufacturing etc. to streaming platforms and online retail, the connections between data centres keep the modern world running. When those connections are interrupted, businesses do not just slow down, they bring them to a complete standstill.

Yet the networks connecting many enterprise data centres were built for a different era. Traditional DC-to-DC links were designed for predictable workloads and stable traffic patterns. Today’s reality is far more dynamic. Enterprises operate across global locations and cloud environments, moving massive volumes of data in real time to support AI workloads and business needs.

In an environment shaped by increasing geopolitical constraints, cable outages, route failures, or sudden spikes in demand, these can quickly cascade into service disruption and operational risk, leading to a costly downtime. In such scenarios, the response is often reactive and manual, consuming valuable time when business need certainty and speed.  

Tata Communications’ IZO™ DC Dynamic Connectivity addresses this challenge by introducing a self-healing, intelligent network that covers key global data centers across 5 continents. Unlike conventional architectures, this platform uses deterministic multi-path routing to deliver predictable latency and performance. This means the platform  is smart enough to automatically re-route traffic within seconds – without manual intervention during disruptions. This enables enterprises to achieve >99.99% service availability across mission-critical infrastructure that supports business-critical applications, turning resilience from a contingency into a default state.

The platform also gives enterprises access over their connectivity. Through a unified digital interface and APIs, enterprises can monitor performance, receive proactive alerts, and dynamically scale bandwidth as workloads evolve. Business leaders no longer have to guess their future needs or over-pay for ‘just in case’ bandwidth. The system provides Al-driven predictive insights allowing companies to forecast their capacity requirements in advance. If a sudden workload demands more capacity or choice of route, users can instantly scale their bandwidth or add route through self-service feature.

The business impact is a shift from crisis management to strategic growth. By moving to a flexible, consumption-based pricing model, enterprises can reduce the need for idle backup capacity and save up to 30% on operational costs. Enterprises can activate resilience and bandwidth only when required, helping optimise costs while maintaining deterministic performance across geographies.

This is the Tata Communications advantage: combining enterprise-grade agility with predictive intelligence to keep the world’s most important data moving and ensuring enterprises are always on and always connected.

Commenting on the launch, Genius Wong, Executive Vice President, Core and Next-Gen Connectivity Services and Chief Technology Officer, Tata Communications, said: “Data centres are the core engines of today’s digital economy, and the connections between them must be as resilient as the networks that connect them. They must be just as dynamic as the applications they support. With IZO™ DC Dynamic Connectivity, we are shifting resilience from a reactive process to an autonomous capability. By combining global reach, deterministic routing and intelligent automation, we are enabling enterprises to build a digital foundation that scales with confidence and operates without disruption.”

About Tata Communications

A part of the Tata Group, Tata Communications (NSE: TATACOMM) (BSE: 500483) is a global digital ecosystem enabler powering today’s fast-growing digital economy in more than 190 countries and territories. Leading with trust, it enables digital transformation of enterprises globally with collaboration and connected solutions, core and next gen connectivity, cloud hosting and security solutions and media services. 300 of the Fortune 500 companies are its customers and the company connects businesses to 80% of the world’s cloud giants. For more information, please visit www.tatacommunications.com       

Forward-looking and cautionary statements

Certain words and statements in this release concerning Tata Communications and its prospects, and other statements, including those relating to Tata Communications’ expected financial position, business strategy, the future development of Tata Communications’ operations, and the general economy in India, are forward-looking statements. Such statements involve known and unknown risks, uncertainties and other factors, including financial, regulatory and environmental, as well as those relating to industry growth and trend projections, which may cause actual results, performance or achievements of Tata Communications, or industry results, to differ materially from those expressed or implied by such forward-looking statements. The important factors that could cause actual results, performance or achievements to differ materially from such forward-looking statements include, among others, failure to increase the volume of traffic on Tata Communications’ network; failure to develop new products and services that meet customer demands and generate acceptable margins; failure to successfully complete commercial testing of new technology and information systems to support new products and services, including voice transmission services; failure to stabilize or reduce the rate of price compression on certain of the company’s communications services; failure to integrate strategic acquisitions and changes in government policies or regulations of India and, in particular, changes relating to the administration of Tata Communications’ industry; and, in general, the economic, business and credit conditions in India. Additional factors that could cause actual results, performance or achievements to differ materially from such forward-looking statements, many of which are not in Tata Communications’ control, include, but are not limited to, those risk factors discussed in Tata Communications Limited’s Annual Reports. 

The Annual Reports of Tata Communications Limited are available at www.tatacommunications.com. Tata Communications is under no obligation to, and expressly disclaims any obligation to, update or alter its forward-looking statements.

^© 2026 Tata Communications Ltd. All rights reserved. TATA COMMUNICATIONS and TATA are trademarks or registered trademarks of Tata Sons Private Limited in India and certain countries. All other third-party trademarks belong to their respective owners.

*DC Stand for Data Centre

A bold cultural experiment turns TikTok’s addictive storytelling style into a gateway for falling in love with books again

KUALA LUMPUR, Malaysia, March 31, 2026 /PRNewswire/ — Today, BookXcess launched The Brain Un-Rot Library, a groundbreaking campaign designed to help reverse the effects of ‘brain rot’, specifically the decline in reading focus caused by endless scrolling and bite-sized dopamine hits from social media.

Comprising 100 of the world’s best loved books, The Brain-Un Rot Library is being released throughout March and April on TikTok. Utilising the fast-paced, deliberately random format of brain rot, it re-engineers the content to foster engagement with compelling narratives from real books by real authors, uniquely retold in native Gen-Z language. From hand-picked titles used in the educational curriculum, like Animal Farm, Wuthering Heights, and 1984, to modern classics and #BookTok Hits like The Hunger Games and Foul Lady Fortune, the library features a wide range of books and genres, designed to appeal to a wide range of young minds.

The format also progressively builds longer text and richer storytelling, gradually re-training brains, ultimately guiding viewers back to immersive reading by engaging them in longer focus and, ultimately, books.

Speaking about the campaign, Prof. Stijn Massar, from the National University of Singapore (NUS), “Our own research shows that people spend an average of 6 hours per day on their phones, which means a lot of people now don’t have the patience to sit through a 60-second video, let alone reading a book. The Brain-Un Rot Library utilises the addictive format of brain rot, re-engineered to foster engagement and focus through compelling narratives from real books by real authors.  I’m excited to see how we could reclaim our attention and rekindle our curiosity for thoughtful, meaningful, and deep engagement with written content.”

Launched at The Sunway Library by BookXcess in Kuala Lumpur, the largest 24-hour bookstore in Southeast Asia, BookXcess also launched the first of its Brain Un-Rot Islands, a dedicated physical version of the Brain Un-Rot Library that will be rolled out nationwide across BookXcess stores.

The campaign could not have come at a better time, as according to research an individual’s average attention span on a digital devices have declined from 2.5 minutes in 2004 to 47 seconds in 2024, driven by how information is now produced, curated or distributed, and consumed, namely through a relentless wave of stimuli that included constant notifications, short-form videos, and infinite scrolling.^[1] 

More importantly, research also revealed that reduced attention span has also disrupted the cognitive processes required for academic success, leading to fragmented learning and lower performance. As a result, students with shorter attention spans often receive lower grades and experience significant academic difficulties.^[2]

Jacqueline Ng, Co-Founder and Executive Director of BookXcess, explained the motivation behind the campaign, “One thing that really concerns me is the impact that shrinking attention spans are having on youth today. Attention and mental health are closely connected, and it’s quite concerning to see how easily the younger generation loses focus after just a short while, even when they are genuinely interested in something. You can’t help but think about how this might affect them in their education and in their daily lives. That’s why the Brain Un-Rot Library is important to us — it’s our way of trying to support young readers and help them slowly build back the ability to focus and enjoy reading again.”

See The Brain Un-Rot Library here: https://www.tiktok.com/@bookxcess.

^[1] Mark, G. (2023). Attention span: A ground-breaking way to restore balance, happiness and productivity

^[2] Media use, attention, mental health and academic performance among 8- to 12-year-old children