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TEWAMOTO Unveils HydraX Electric Personal Watercraft Concept at the Miami International Boat Show

MIAMI, Feb. 14, 2026 /PRNewswire/ — TEWAMOTO, a U.S.-registered and globally focused mobility brand, unveiled its HydraX electric personal watercraft design concept at the Miami International Boat Show, showcasing its latest vision for high-performance electric mobility on the water.

TEWAMOTO showcases its HydraX electric personal watercraft concept model at the Miami International Boat Show.
TEWAMOTO showcases its HydraX electric personal watercraft concept model at the Miami International Boat Show.

“HydraX is more than a design concept — it reflects TEWAMOTO’s long-term thinking about the future of water mobility,” said Wayne Wang, Founder and Chief Operating Officer of TEWAMOTO. “We believe that meaningful electrification is not simply about changing the power source, but about redefining the balance between performance, freedom, and environmental responsibility. With HydraX, we aim to demonstrate that high-performance water sports can be clean, quiet, and genuinely enjoyable.”

As the global marine and water sports industry continues to transition toward electrification and sustainability, TEWAMOTO positions HydraX as a forward-looking exploration of how power, environmental impact, and real-world usability can be integrated into the next generation of personal watercraft.

HydraX and the Future of Electric Personal Watercraft Performance

HydraX is a fully electric personal watercraft concept designed for individual water sports enthusiasts who seek exceptional performance while also valuing sustainability and long-term cost efficiency.

Developed around real-world riding scenarios, HydraX addresses several key limitations of traditional gas-powered personal watercraft, including noise, emissions, restricted water access, and high maintenance costs. Its core highlights include:

  • Fully electric propulsion, delivering zero emissions and low noise, enabling access to more regulated and environmentally sensitive waterways.
  • A high-output electric powertrain exceeding 240 horsepower, positioning HydraX among the most powerful electric personal watercraft concepts in the industry.
  • 5C ultra-fast charging capability, allowing the battery to recharge from 30% to 90% in approximately five minutes, significantly reducing downtime.
  • Lower total cost of ownership, minimizing long-term maintenance and energy expenses while enhancing overall riding enjoyment.

Rather than focusing solely on peak performance figures, HydraX emphasizes stable power delivery, usability, and reliability across high-frequency riding scenarios, reflecting TEWAMOTO’s user-centered approach to electric mobility design.

Miami: A Global Stage for the Future of Electric Water Mobility

The Miami International Boat Show is one of the world’s most influential events for the marine and water sports industry, bringing together leading brands, professionals, and enthusiasts from around the globe. TEWAMOTO’s decision to debut HydraX at the show underscores its commitment to engaging the global market in a broader dialogue on the next phase of electric personal watercraft development.

The unveiling of HydraX also marks an important milestone in TEWAMOTO’s expansion beyond electric two-wheel mobility, extending its technological capabilities and design philosophy into water-based applications.

About TEWAMOTO

As a U.S.-registered, based, and globally focused international company, TEWAMOTO brings together top talent in design, engineering, and manufacturing from around the world. Our mission is simple yet ambitious: to deliver clean, powerful, and fun mobility experiences for the next generation of riders. We are not just building vehicles — we are building a new way of moving, playing, and living with energy.

BougeRV Launches the All-New Constant-Temp Metal Water Heater: Professional-Grade Comfort for Off-Grid Living

All-in-one outdoor water heating solution features 3-second flash heating, precise ±1°F temperature control, multi-power compatibility, and advanced safety protection

HOUSTON, Feb. 14, 2026 /PRNewswire/ — BougeRV, a leader in portable outdoor appliances and energy solutions, today announced the launch of its Portable Propane Water Heater, a compact, high-performance system designed to provide instant hot water for campers, overlanders, RV travelers, and outdoor enthusiasts seeking comfort and convenience in off-grid environments.

BougeRV Outdoor Portable Propane Water Heater
BougeRV Outdoor Portable Propane Water Heater

Engineered for reliability and ease of use, the BougeRV Portable Propane Water Heater delivers hot water in as little as three seconds and features a streamlined, three-step setup process. Built for rugged outdoor use, the unit combines advanced temperature stability, multiple power options, and layered safety protections in a portable, user-friendly design.

“Outdoor experiences shouldn’t mean sacrificing comfort or convenience,” said Jason Zheng, a BougeRV spokesperson. “Our portable propane water heater was designed to give adventurers reliable, easy-to-use hot water wherever their journey takes them — from remote campsites to overlanding expeditions and roadside needs.”

Instant Hot Water Designed for Off-Grid Living

The BougeRV Portable Propane Water Heater offers flash heating technology that eliminates long wait times for hot water, allowing users to quickly shower, wash gear, or clean cookware in remote environments. The system supports adjustable water temperatures between 70°F and 118°F, while maintaining precise heat control within ±1°F for consistent performance.

A built-in smart temperature lock preserves water temperature for up to two minutes when paused, allowing users to resume showers without waiting for reheating.

Flexible Power and Efficient Performance

Designed for versatility, the water heater supports three power options, including AC outlet, DC 12V vehicle socket, and propane operation, giving users flexibility across camping, road trip, and vehicle-based travel scenarios.

The system also features three adjustable flow modes — low, medium, and high — enabling users to balance water efficiency with comfort based on available water supply and outdoor conditions.

Built for Durability and Portability

Constructed with a sleek metallic shell and IPX4 water resistance rating, the BougeRV Portable Propane Water Heater is designed to withstand demanding outdoor environments. Its ultra-compact form factor measures approximately 15.55 × 12.50 × 6.69 inches, allowing for easy storage and transport.

Additional design features include:

  • Magnetic mounting capability for vehicle attachment and hands-free overhead shower use
  • Lightweight, one-handed carry portability
  • Quick 60-second setup with pump, shower, and propane connection

Advanced Multi-Layer Safety Protection

BougeRV integrates a comprehensive 5-way safety shield that includes:

  • Tilt protection
  • Anti-scald temperature protection
  • Gas safety monitoring
  • Windproof design
  • Automatic shutoff when no water flow is detected

The unit also features high-temperature shutdown protection to maintain safe operation in outdoor environments.

Availability

The BougeRV Portable Propane Water Heater is available now with an MSRP of $399.99. Order now on our official website to enjoy the exclusive pre-sale price of $319.99. The product is also available for purchase on Amazon.

About BougeRV

BougeRV is dedicated to empowering outdoor adventurers with reliable, portable, and high-performance appliances. Through a thoughtfully designed ecosystem of outdoor appliances, batteries, and solar solutions, BougeRV helps consumers go further, stay longer, and live better — wherever their journeys lead.

Milano Cortina 2026 Licensed Candies Released Globally

Developed by Amos Sweets, the collection brings together playful designs, innovative textures, and interactive candy experiences inspired by the Olympic Winter Games Milano Cortina 2026.

MILAN, Feb. 14, 2026 /PRNewswire/ — The Milano Cortina 2026 licensed candy collection, developed by Amos Sweets under licence from the International Olympic Committee, has been released to bring playful and innovative treats to fans and candy lovers. Created specifically for the occasion, the collection features fun designs, unique textures, and interactive experiences that add a touch of sweetness in the celebration of the Winter Olympics.

AMOS Milan-Cortina 2026 Licensed Product Collection KV
AMOS Milan-Cortina 2026 Licensed Product Collection KV

 

AMOS Milan-Cortina 2026 (Paralympic) Licensed Product Collection KV
AMOS Milan-Cortina 2026 (Paralympic) Licensed Product Collection KV

The collection includes the following creative candies:

4D Mascot Gummies – Featuring three-dimensional shapes of the official Olympic and Paralympic mascots, offering a fun and collectible treat experience.

4D Gummy Mascot & Toy Box – Combining 4D mascot gummies with exclusive mascot figurines for an interactive unboxing delight.

TastySounds Music Lollipops – Integrating bone-conduction audio technology with candy, these lollipops play the official Milano Cortina 2026 song Fino all’alba (Until the Dawn) and create a new multi-sensory way to enjoy sweets.

Peelerz Mango Gummies – A peelable mango-shaped gummy with a soft inner center, encouraging playful sharing and exploration — echoing the Olympic spirit of discovery and connection.

Under the IOC licence, the Milano Cortina 2026 candy collection will be available across key global markets, including the European Union, the United Kingdom, the United States, Canada, China, Japan, and South Korea. Distribution in each market complies with the applicable local licensing scope and regulatory requirements.

Available through selected offline and online channels, the collection invites fans and candy lovers alike to celebrate the Olympic spirit through playful, interactive treats that add a touch of sweetness to every moment of the Olympic Winter Games.

ABOUT AMOS FOOD GROUP

Founded in 2004, Amos Food Group is a global confectionery enterprise integrating manufacturing, research and development, and brand management. Guided by its mission to be “the sweet messenger to the world,” the Group delivers joyful and imaginative candy experiences to consumers in more than 75 countries and regions worldwide.

Ranked No. 66 in the 2025 Global Top 100 Candy Companies by Candy Industry, Amos has received international recognition, including the Most Innovative New Products Awards from the National Confectioners Association (USA) and the Superior Taste Awards from the International Taste Institute.

Its flagship brand Amos represents Happiness, known for viral innovations such as Peelerz peelable gummies, 4D Gummies, and TastySounds™ music lollipops. Its nutraceutical gummy brand Biobor represents Health, offering functional gummies formulated with carefully selected nutrients. Through continuous innovation and global partnerships, Amos Food Group brings creativity, joy, and meaningful sweet moments to consumers worldwide.

About the IOC Global Licensing Programme

The licensing agreement between the IOC and Amos Food is the result of the IOC’s Global Licensing Strategy that aims to engage and connect fans through official licensed products that strengthens and promotes the Olympic brand, not only during the Olympic Games, but between Games editions as well.

Alongside the Olympic and Paralympic Games Collections, which celebrate each upcoming edition of the Games, and include a wide range of accessories, souvenirs, fan gear and apparel, the IOC’s core licensing programmes include the Olympic Heritage Collection, which offers products featuring art and design elements from previous Games, and the Olympic Collection, which seeks to engage a young and active audience through unique branded products such as apparel, toys and games, bags, stationery items and sports equipment.

Through the sale of official licensed products, collectables and souvenirs, the Olympic licensing programmes provide fans with a tangible connection to the Olympic Games and the Olympic values. Olympic merchandising items are available for sale at the Olympic Shop.

HTX and AINFT Collaborate to Build New Web3 AI Gateway, Offering Free Access to Leading AI Models and 40,000 USDT Prize Pool

PANAMA CITY, Feb. 14, 2026 /PRNewswire/ — As global artificial intelligence capabilities continue to advance and Web3 infrastructure matures, AI and the crypto ecosystems are entering a new phase of seamless integration. HTX has recently collaborated with AINFT to co-hosted a special AI Challenge campaign featuring a combined prize pool of 40,000 USDT. This innovative event invites users worldwide to experience a new generation of Web3-native AI access.

AINFT: Web3 Gateway to AI

AINFT positions itself as a Web3-native AI gateway designed to provide permissionless, seamless access to leading large language models (LLMs). Users can log in instantly by signing via a TronLink wallet, eliminating the need for email registration or KYC verification and enabling direct on-chain identity authentication. The platform integrates top-tier AI models including Claude Opus 4.5, ChatGPT-5.2, and Gemini 3 Pro, offering unified access for dialogue, reasoning, and content creation across multiple scenarios.

To lower entry barriers, AINFT provides each new user with a one-time allocation of one million free points, allowing immediate access to premium AI models without upfront payment. Once the free quota is exhausted, users can top up on demand using USDT, USDD, USD1, TRX, or NFTs on the TRON network. The platform’s official TRC20 token, $NFT, offers an additional 20% bonus in points when used for payment, supporting a flexible pay-as-you-go model with no subscription requirements.

40,000 USDT Prize Pool: Multiple Rewards in the Second Season

The campaign runs through March 13 at 08:00 (UTC). Following strong engagement in the first phase, Season 2 was launched with an initial 4,000 USDT prize pool unlocked. The overall campaign prize pool totals 40,000 USDT. To participate, users must log in to AINFT’s official website, connect their TronLink wallet, submit their HTX UID and wallet address through the designated form, and complete both the AI challenge tasks on AINFT and the trading tasks on HTX. 

AINFT AI Challenge Offers 13,000 USDT Prize Pool

Users who log in to AINFT and participate in the challenge can compete for three separate prize pools.

  1. Boosted Gift Package: Unlocks progressively based on the number of valid connected wallets within the community. For Season Two, if the valid address count reaches 5,000, the rewards of up to 7,000 USDT will be activated.
  2. Early Bird Gift Package: Rewards the first 500 users each season who connect via TronLink and claim their initial points. 25 users will be selected per season to receive 20 USDT each.
  3. Deposit Gift Package: Users who complete a deposit of any amount during the period will automatically enter a lucky draw. Twenty winners will be selected to share 500 USDT.

Exclusive Triple Rewards for HTX Users: Share 27,000 USDT

Users who complete the registration form and submit their HTX UID and TronLink wallet address can unlock three exclusive incentives:

  • Point Bonus: 1 million points will be awarded to HTX users who access AINFT through the designated link and connect a TronLink wallet. [Join now >>]
  • Welcome Bonus: A 20 USDT bonus is available for users who join AINFT events and sign up for an HTX account during the campaign. Limited to the first 950 registered users.
  • Trading Reward: Users who complete HTX trading tasks—at least 100 USDT in spot volume or 500 USDT in futures volume—will receive a 40 USDT airdrop. Limited to the first 200 qualified users.

Ecosystem Synergy: Practical Case of AI and Crypto

As a global exchange that has long focused on AI-related sectors and innovative asset discovery, HTX continues to support high-quality AI projects and promote collaboration across technology, traffic, and users. As AI computing demand increases and crypto payment systems mature, decentralized AI portals are expected to become cornerstones of next-generation Web3 infrastructure.

The collaboration between HTX and AINFT represents a forward-looking position within this trend. Looking ahead, HTX will continue working with high-quality ecosystem partners to build a more open, efficient, and sustainable Web3 innovation network, providing global users with forward-looking digital asset opportunities and application experiences.

About HTX

Founded in 2013, HTX (formerly Huobi) has evolved from a virtual asset exchange into a comprehensive ecosystem of blockchain businesses that span digital asset trading, financial derivatives, research, investments, incubation, and other businesses.

As a world-leading gateway to Web3, HTX harbors global capabilities that enable it to provide users with safe and reliable services. Adhering to the growth strategy of “Global Expansion, Thriving Ecosystem, Wealth Effect, Security & Compliance,” HTX is dedicated to providing quality services and values to virtual asset enthusiasts worldwide.

To learn more about HTX, please visit https://www.htx.com/ or HTX Square , and follow HTX on X, Telegram, and Discord.

Shining in Hong Kong: HTX Ventures and HTX DAO Attend Consensus 2026, Advancing a Sustainable Web3 Ecosystem

PANAMA CITY, Feb. 14, 2026 /PRNewswire/ — Consensus Hong Kong 2026 was successfully held from February 11-12, bringing together global blockchain leaders, developers, and institutional investors. As key industry participants, HTX Ventures and HTX DAO took part in the main conference and a series of high-level satellite events, presenting their long-term strategic roadmap for propelling technical innovation and ecosystem development.


HTX Ventures at Consensus 2026: Justin Sun Delivers Keynote Speech

During the conference, HTX Ventures highlighted its continued focus on early-stage innovation, foundational infrastructure, and global ecosystem synergy. With increasingly defined global regulatory frameworks and maturing digital asset infrastructure, the platform emphasized forward-looking investments across AI, Web3, Real-World Assets (RWA), and modular blockchains. HTX Ventures engaged in in-depth exchanges and strategic resource matchmaking with developers, investment institutions, and project teams from around the globe.

HTX Ventures at Consensus Hong Kong 2026
HTX Ventures at Consensus Hong Kong 2026

On February 12, Justin Sun, Founder of TRON and Advisor to HTX, delivered a keynote speech at the main forum titled “Building Resilient Blockchain Infrastructure for a World in Constant Change.”

Justin Sun keynotes at the main forum.
Justin Sun keynotes at the main forum.

HTX DAO at GWDC 2026: Deepening Engagement in the Developer Ecosystem

Ahead of Consensus, HTX DAO appeared as a Gold Sponsor at Global Web3 Dev Con 2026 (GWDC 2026), held February 8-9 at Hong Kong Cyberport.

At the conference, HTX DAO Ambassador Molly delivered a speech titled “The DAO Path: Decentralization Without Dogma.” Her speech provided a candid reflection on HTX DAO’s evolution and practices on the concept of “The People’s Exchange.”

Molly shared that in its early stages, the team explored radical decentralization models, including proposals to burn 99% of the token supply through community voting. While such experiments embodied strong democratic ideals, they also revealed structural vulnerabilities: emotional, short-term decision-making could undermine long-term ecosystem stability. Over time, the community reached a shared understanding: neither hype-driven proposals nor radical operations bolster token price in the long run. Instead, value is anchored in sound tokenomics, sustainable real-world utility, and a steadfast foundation of long-term holders.

Consequently, over the past two years, HTX DAO has shifted toward a more balanced governance architecture built on three pillars:

  • Optimized Tokenomics: A transparent deflation mechanism to strengthen market trust. This includes allocating 50% of HTX’s quarterly revenue to $HTX token burns—a commitment formally integrated into the whitepaper with regular disclosure of revenue and burn data.
  • Pragmatic On-chain Governance: The DAO preserves community participation while avoiding “performative decentralization” detached from operational sustainability.
  • A Culture of Longtermism: The platform embeds real economic incentives into governance design, ensuring holders benefit from asset growth and risk mitigation.

According to the official data, HTX DAO’s token holder addresses have expanded from approximately 40,000 in its early phase to over 800,000 today. Amid significant market volatility, $HTX has demonstrated relative stability, an outcome the team attributes to its structured tokenomics. At the same time, the team hosted dozens of global offline meetups, spanning various countries and regions to foster direct engagement with their community. This effort has been instrumental in transforming the DAO vision into a tangible reality for users worldwide.

Molly also outlined the DAO’s three major initiatives for 2026:

  • Opening on-chain product interfaces to global developers to foster co-creation and innovation
  • Launching dedicated support programs for emerging narratives such as RWA
  • Expanding volunteer and ambassador systems to cultivate a diverse DAO culture and advance governance

Molly keynotes at GWDC 2026.
Molly keynotes at GWDC 2026.

Expanding the Global Web3 Footprint Through Strategic Engagement

Beyond the developer summit, HTX Ventures and HTX DAO participated in multiple high-profile side events in Hong Kong to boost their global influence.

On February 9, representatives of both platforms attended the “Alpha Night,” hosted by MyToken. During this gathering, which brought together top-tier alpha hunters and institutional investors, the HTX Ventures team established deep connections with numerous high-potential projects, demonstrating their keen insight in identifying premium early-stage assets.

The following day, February 10, HTX DAO appeared as a brand-certified partner at the “Build and Scale in 2026” forum, co-hosted by ChainCatcher, RootData, and Alibaba Cloud.

Throughout this visit to Hong Kong, HTX Ventures and HTX DAO demonstrated their comprehensive penetration into the Web3 space. Moving forward, both platforms will remain committed to the vision of “Building a Metaverse Free Port.” Through continuous ecological investment and collaborative industry development, they aim to lead the industry through market cycles and usher in the next golden era of the crypto world.

About HTX Ventures

HTX Ventures is the global investment arm of HTX, integrating investment, incubation, and research to identify and discover the best and most innovative projects in the market. Visit us here.

 

Login Now & Claim Rewards! HTX Unveils 3,000,000 USDT Mega Airdrop

PANAMA CITY, Feb. 14, 2026 /PRNewswire/ — As the Lunar New Year approaches, HTX is proud to announce the launch of its flagship festive event: the Mega Spring Festival Airdrops. To usher in the Year of the Horse with prosperity and fortune, HTX has committed a massive 3,000,000 USDT prize pool for its global community. Running from February 15, 03:00 (UTC) to March 3, 03:00 (UTC), this comprehensive campaign marks the year’s first major digital asset celebration, featuring daily login rewards, community engagement challenges, “trade & draw” mechanics, and social sharing incentives.


Log in to Claim Your Share of 2,600,000 USDT in Airdrops

During the event, users can claim daily airdrops simply by logging into the HTX App at 03:00 (UTC) and visiting any Spot, Margin, or Futures trading page. Each airdrop contains a randomized selection of rewards, including popular cryptocurrencies, Trading Fee Rebate Vouchers, Futures Trial Bonuses, 0% Margin Interest Vouchers, and APY Booster Coupons. Individual participants can win up to 2,026 USDT!

By removing entry barriers and offering diverse rewards, HTX strives to deliver a seamless “Instant Login Rewards” experience, ensuring that every member of our global community can enjoy effortless participation and immediate rewards.

HTX Community Interaction: 300,000 USDT Giveaway Frenzy

The campaign also introduces the “Ride the Golden Trend” feature, allowing users to earn airdrops directly through the app homepage and comment sections. By exploring the K-line comment sections for designated tokens, users can claim valuable surprise gifts daily at 03:00 (UTC).

HTX has partnered with seven distinguished Diamond Partners—SUN, JST, NFT, BTT, WIN, TRX, and STEEM—to present an exclusive, cross-project “Surprise Gifts” mega drop. Users who engage with the K-line comments for these seven tokens will have the opportunity to claim exclusive rewards on a first-come, first-served basis. Additionally, those who comment daily on relevant posts within the HTX community section will unlock a special, large-scale airdrop during the Lantern Festival.

Complete Tasks for a Chance to Win Big in the 50,000 USDT Lucky Draw

HTX is boosting the festive spirit with a high-stakes lucky draw. By completing simple trades or interactive tasks, users can compete for a 50,000 USDT total prize pool, with a grand prize of 18,888 USDT.

  • Boost Your Odds: Trading designated tokens (SUN, JST, NFT, BTT, WIN, TRX, and STEEM) in Spot or Futures markets will count for triple (3x) the trading volume toward task calculations, significantly increasing your chances of winning.

Visit the event page>>

Send Crypto Gifts to Friends and Share 50,000 USDT

The Lunar New Year is a season for sharing. During this event, users whosend an HTX Crypto Gift of 10 USDT or more to friends will earn a cash reward of up to 20 USDT once the gift is claimed.  This 50,000 USDT prize pool is available on a first-come, first-served basis. This “Share Crypto Gifts & Get Reimbursed” model is designed to foster a cycle of prosperity and luck among friends and family. 

Send Crypto Gifts>>

Compliance, Transparency, and Fairness

To ensure a level playing field, HTX is dedicated to maintaining the highest standards of transparency and equity. The platform strictly monitors for irregular activities to ensure a secure environment.

  • Limit: Each device is limited to one airdrop claim per day.
  • Distribution: All rewards will be credited to the winner’s “My Rewards” section or “Assets” in accordance with the event rules.

HTX remains committed to its user-centric philosophy, continuously expanding its asset ecosystem and creative reward systems. This Mega Spring Festival Airdrop is a sincere expression of gratitude for the continued loyalty of our users. As we embark on a new journey of wealth in the 2026 Year of the Horse, HTX ensures that every login is a step toward a prosperous future.

The luck begins here—let the rewards keep rolling in!

About HTX

Founded in 2013, HTX (formerly Huobi) has evolved from a virtual asset exchange into a comprehensive ecosystem of blockchain businesses that span digital asset trading, financial derivatives, research, investments, incubation, and other businesses.

As a world-leading gateway to Web3, HTX harbors global capabilities that enable it to provide users with safe and reliable services. Adhering to the growth strategy of “Global Expansion, Thriving Ecosystem, Wealth Effect, Security & Compliance,” HTX is dedicated to providing quality services and values to virtual asset enthusiasts worldwide.

To learn more about HTX, please visit https://www.htx.com/ or HTX Square , and follow HTX on X, Telegram, and Discord

 

Alphamab Oncology Announces the First Patient Dosed in a Phase III Clinical Study for Colorectal Cancer of Biparatopic HER2-targeting ADC JSKN003

SUZHOU, China, Feb. 14, 2026 /PRNewswire/ — Alphamab Oncology (stock code: 9966.HK) announced that the first patient has been successfully dosed in the Phase III clinical study (Study ID: JSKN003-005) of the biparatopic HER2-targeting antibody-drug conjugate (ADC) JSKN003, for the treatment of HER2-positive advanced colorectal cancer (CRC). JSKN003 is independently developed by the Company, and co-developed with JMT-Bio Technology Co., Ltd., a wholly-owned subsidiary of CSPC Pharmaceutical Group Co., Ltd. (stock code: 1093.HK).

Colorectal cancer is among the most common malignancies worldwide. China has a high incidence of CRC, with over 500,000 new cases diagnosed annually. Approximately 83% of patients are initially diagnosed at an advanced stage, and about 44% already have distant metastases to organs such as the liver or lungs. Despite advances in systemic therapies, the 5-year survival rate for patients with metastatic CRC remains below 20%, indicating a poor prognosis. There are currently no HER2-targeted therapies approved in China for CRC. For patients with HER2-positive advanced CRC who have failed prior treatments with oxaliplatin, fluorouracil and irinotecan, the median progression-free survival (mPFS) of approved therapies is only 2.0 to 3.7 months, and the median overall survival (mOS) is approximately 7 to 10 months. There remains a significant unmet clinical need within this patient population. Early clinical data of JSKN003 are promising, and JSKN003 has been granted Breakthrough Therapy Designation by the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) for this indication. According to the data presented at the 2025 European Society for Medical Oncology (ESMO) Congress, JSKN003 demonstrated an objective response rate (ORR) of 68.8% and a mPFS of 11.04 months in 32 patients with HER2-positive advanced colorectal cancer, showing a clear therapeutic advantage over existing therapies.

JSKN003-005 is a randomized, open-label, controlled, multicenter Phase III clinical study designed to evaluate the efficacy and safety of JSKN003 versus investigator’s choice of regimen (regorafenib/fruquintinib/trifluridine tipiracil) in HER2-positive advanced CRC patients who have failed prior oxaliplatin, fluorouracil, and irinotecan therapy. The primary endpoint is PFS assessed by blinded independent central review (BICR) according to RECIST v1.1. Secondary endpoints include OS, as well as investigator-assessed PFS and ORR, disease control rate (DCR), duration of response (DOR), time to response (TTR), and other endpoints evaluated by BICR/investigator according to RECIST v1.1. The rapid progression of this study marks a critical stage in the development of JSKN003 for colorectal cancer, and is expected to provide patients with a new therapeutic option.

About JSKN003

JSKN003 is developed by site-specific conjugation to the Fc glycans of anbenitamab, resulting in a homogeneous and stable ADC with a DAR of 4. JSKN003 binds to two HER2 epitopes on tumor cells and release topoisomerase I inhibitors through cellular endocytosis, exerting anti-tumor effects.

Compared to similar ADCs, JSKN003 demonstrates better serum stability, reduced hematological toxicity, and stronger tumor inhibition and bystander effect, resulting in significantly wider therapeutic window.

Multiple registrational studies of JSKN003 are ongoing, including trials in HER2-positive breast cancer (BC), all-comer platinum-resistant ovarian cancer (PROC), HER2-low BC, and HER2-positive colorectal cancer (CRC).

JSKN003 has been granted Orphan Drug Designation (ODD) by the U.S. Food and Drug Administration (FDA) for gastric cancer (GC) and gastroesophageal junction cancer (GEJ), has been granted Fast Track Designation (FTD) by the FDA for the treatment of advanced or metastatic platinum-resistant recurrent epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer (PROC), not restricted by HER2 expression, has been granted Breakthrough Therapy Designation (BTD) by the FDA for the treatment of patients with HER2-expressing PROC who have received prior treatment with bevacizumab. It has also been granted two BTDs by the National Medical Products Administration (NMPA) for PROC and HER2-positive advanced CRC that has failed prior oxaliplatin, fluorouracil, and irinotecan therapy.

In September 2024, the Company entered a licensing agreement with JMT-Bio Technology Co., Ltd. (“JMT-Bio”), a wholly-owned subsidiary of CSPC Pharmaceutical Group Co., Ltd. (“CSPC”) (stock code: 1093.HK). JMT-Bio was granted the exclusive license and sublicense rights to develop, sell, offer for sale and commercialize JSKN003, for tumor-related indications in mainland China (excluding Hong Kong, Macau or Taiwan). Alphamab retains exclusive production rights for JSKN003.

About Alphamab Oncology

Alphamab Oncology (Stock Code: 9966.HK) is an innovative biopharmaceutical company focused on oncology. Leveraging proprietary platforms-including single-domain antibodies, bispecific antibodies, glycan-specific conjugation, linker-payloads, dual-payload ADCs, and high-concentration subcutaneous formulations, the Company has built a differentiated and globally competitive pipeline, covering cutting-edge candidates in ADCs, bispecific antibodies, and single-domain antibodies.

One product has received market approval: Envafolimab (KN035, brand name: 恩维达®), the world’s first subcutaneously injected PD-(L)1 inhibitor, offering greater convenience and accessibility in cancer treatment. The NMPA has accepted the new drug application for KN026 (Anbenitamab Injection), a HER2 bispecific antibody, for second-line or later HER2-positive gastric cancer. Four bispecific ADC candidates have entered clinical stages, and next-generation ADC pipelines—such as dual-payload ADCs—are advancing rapidly. The Company has established strategic partnerships with organizations including CSPC, ArriVent, and Glenmark, covering both product development and technology platforms.

Our overarching mission is to make cancer manageable and curable by addressing unmet clinical needs in oncology. Alphamab Oncology is continuously dedicated to the development of effective, safe, and globally competitive anti-tumor drugs, delivering China-innovated cancer therapies to benefit patients worldwide.

Visa-Free Policies Fuel New Trend in Medical Tourism: International Patients Praise Parkway in Shanghai

SHANGHAI, Feb. 14, 2026 /PRNewswire/ — With the implementation of 144-hour visa-free transit across multiple cities in China, international visitors now enjoy significantly greater convenience. Recently, an intriguing trend has emerged: many foreign nationals arriving in Shanghai for business or tourism are now incorporating “health management” or “convenient medical access” into their packed itineraries, blurring the lines between “leisure travel to China” and “medical travel in China”. Parkway MediCentre Xintiandi, located in the heart of downtown Shanghai, and Parkway Shanghai Hospital, situated near the Hongqiao transportation hub, are increasingly favored by international patients for their high-quality, internationally aligned healthcare services, strategic locations, and seamless communication.

Having been rooted in Shanghai for over two decades, Parkway has witnessed and contributed to the “golden era” of the city’s—and the nation’s—opening-up. To date, Parkway has served nearly 500,000 patients from 77 countries and regions, and has been designated as an official medical examination provider for several embassies, including those of the United Kingdom, Canada, and New Zealand. This extensive international service experience and brand trust position Parkway as a key bridge connecting global health needs with Shanghai’s premium healthcare resources.

As one of the first international high-quality healthcare providers to enter China, Parkway continues to optimize its service network in Shanghai. Through a three-tiered service system—integrating a comprehensive hospital, medical centers, and community clinics across Huangpu, Changning, Minhang, and Pudong—Parkway ensures citywide coverage and efficient linkage with the Yangtze River Delta healthcare ecosystem, continuously enhancing the accessibility and coordination of regional medical services.

As a comprehensive medical institution, Parkway Shanghai Hospital derives its core strength from a highly experienced medical team, complemented by its proximity to Hongqiao International Airport. The hospital offers multidisciplinary outpatient services staffed by full-time seasoned physicians and also leverages an extensive network of high-quality medical resources, including collaborations with nearly 300 clinically experienced experts from Shanghai’s Class A Tertiary hospitals. Through a streamlined appointment system, patients can efficiently access the specialists they need, completing the entire process—from consultation and diagnosis to treatment planning—in a comfortable environment, effectively eliminating long waiting times. Whether for joint replacement, gallbladder surgery, or thyroid cancer surgery—common or complex procedures—patients receive professional, seamless, and high-quality care.

Besides, Parkway MediCentre Xintiandi, Parkway Medical Clinic Gubei, and Parkway Medical & Dental Clinic Biyun cater to medical needs in commercial hubs and tourist-heavy areas. The Parkway MediCentre Xintiandi, spanning nearly 7,000 square meters in the city center, offers fast, precise, and personalized healthcare services tailored to travelers with tight schedules. Two services are particularly noteworthy. To accommodate patients requiring special preparation, the center provides overnight health screening packages, allowing patients to check in the day before their tests to a well-equipped, private observation room. This ensures a comfortable and convenient environment for necessary preoperative or pre-examination preparation. The following morning, patients can efficiently complete their tests, optimizing both time utilization and overall experience. For eligible minor to moderate surgeries, the center has optimized its procedures to enable patients to safely complete admission, surgery, recovery observation, and discharge within 24 hours—saving significant time and offering particular value to business professionals who cannot afford prolonged interruptions to their schedules.

As China continues to deepen its opening-up, Shanghai’s appeal as an international metropolis is increasingly evident in its healthcare sector. With its distinctive brand advantages, strategic locations, and patient-centric service model, Parkway is redefining the “international medical travel” experience, serving as a vital bridge between global healthcare demands and Shanghai’s premier medical resources.