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HKU engineering researchers develop revolutionary diamond fabrication technology


HONG KONG SAR – Media OutReach Newswire – 20 December 2024 – A research team led by Professor Zhiqin Chu, Associate Professor in the Department of Electrical & Electronic Engineering, and Professor Yuan Lin, Professor in the Department of Mechanical Engineering, Faculty of Engineering at the University of Hong Kong (HKU), has developed a groundbreaking method for massively producing ultrathin and ultra-flexible diamond membranes, in collaboration with Professor Kwai Hei Li, Assistant Professor of the Southern University of Science and Technology, and Professor Qi Wang, Professor of the Dongguan Institute of Opto-Electronics of Peking University.

HKU engineering researchers develop revolutionary diamond fabrication technology
HKU engineering researchers develop revolutionary diamond fabrication technology

These ultrathin and ultra-flexible diamond membranes are compatible with existing semiconductor manufacturing technologies, and thus can, in principle, be fabricated into a variety of electronic, photonic, mechanical, acoustic, and quantum devices.

The innovative edge-exposed exfoliation method discovered by the team facilitates the rapid production of scalable, free-standing diamond membranes. This approach is superior to traditional methods, which are typically time- and costly and limited in size. Remarkably, the new process can manufacture a two-inch wafer within 10 seconds, offering unmatched efficiency and scalability.

These ultra-flat diamond surfaces, essential for high-precision micromanufacturing, along with the flexibility of the membranes, open up new possibilities for next-generation flexible and wearable electronic and photonic devices. The research team envisions significant industrial applications in electronics, photonics, mechanics, thermics, acoustics, and quantum technologies.

“We hope to promote the usage of the high-figure-of-merit diamond membrane into various fields, and to commercialise this cutting-edge technology and deliver premium diamond membranes, setting a new standard in semiconductor industry. We are eager to collaborate with academic and industry partners to bring this revolutionary product to market and accelerate the arrival of diamond era,” concluded Professor Chu.

Diamonds, renowned globally as valuable gemstones, possess exceptional versatility in various scientific and engineering applications. They are the hardest natural material, boasting unparalleled thermal conductivity at room temperature, extremely high carrier mobility, dielectric breakdown strength, an ultrawide bandgap, and optical transparency spanning from the infrared to the deep-ultraviolet spectrum. These remarkable properties make diamonds ideal for fabricating advanced high-power, high-frequency electronic devices, photonic devices, and heat spreaders to cool high-power density electronic components, such as those in processors, semiconductor lasers, and electric vehicles. However, the inert nature and rigid crystal structure of diamonds pose significant challenges in fabrication and mass production, particularly for ultrathin and freestanding diamond membranes, thereby restricting their widespread usage.

The full paper can be accessed here: https://www.nature.com/articles/s41586-024-08218-x

About Professor Zhiqin Chu

Prof. Zhiqin Chu received his B.S. and Ph.D. degrees in Physics from Northwest University (China) and The Chinese University of Hong Kong, in July 2008 and July 2012, respectively. After spending one year as a postdoctoral fellow in the same group, he conducted postdoctoral research at The University of Stuttgart (Germany) from April 2014 to September 2016. Since November 2018, he has been an Assistant Professor in the Department of Electrical and Electronic Engineering (with a joint appointment in the School of Biomedical Sciences) at The University of Hong Kong, and was promoted to tenured Associate Professor in November 2024. Since joining HKU, Prof. Chu has published over 60 peer-reviewed articles in journals such as Nature, Nature Communications, and Science Advances, and has filed 14 patents related to diamond technology. Prof. Chu has received multiple awards, including the Gold Medal at the 2023 International Invention Innovation Competition in Canada (iCAN), the Top 10 Best Invention Award at the 2023 iCAN, the Silver Medal at the 2022 Inventions Geneva Evaluation Days, and the Gold Medal at the 2024 International Exhibition of Inventions of Geneva.

About Professor Yuan Lin

Prof. Yuan Lin earned his B.S. and M.S. in Engineering Mechanics from Tsinghua University, followed by another M.S. in Applied Mathematics and a Ph.D. in Solid Mechanics from Brown University. He joined The University of Hong Kong in 2008 and is now a full Professor in the Department of Mechanical Engineering. His research on cell/tissue mechanics and mechanics of functional materials led to publications in top journals, including Nature, PNAS, Nature Communications, Science Advances and PRL. Prof. Lin has served as Chair of the Gordon Research Conference on Nano-Mechanical Interfaces and keynote speaker in numerous international conferences. As the PI or Co-PI, he has secured more than 15 research grants. Prof. Lin currently serves as the Secretary for the Hong Kong Society of Theoretical and Applied Mechanics.

Hashtag: #HKU

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Rising Costs Prompt Market Reform Proposals

Local shop in Laos (Photo: IDSALA)

National Assembly Representative for Vientiane Capital, Valy Vethsaphong, has called on the Lao government to address the rising prices of essential goods, despite the stability of the country’s exchange rates. Speaking at the 8th Ordinary Session of the Vientiane Capital People’s Assembly on 18 December, Valy highlighted the financial strain facing many citizens, particularly civil servants, who are struggling to meet their daily expenses.

Agilis Robotics completes world’s first robot-assisted bladder tumour resection in clinical trial


HONG KONG SAR – Media OutReach Newswire – 20 December 2024 – Agilis Robotics has announced the successful completion of the world’s first robot-assisted en-bloc resection of a bladder tumour (ERBT) using its self-developed, fully flexible endoscopic surgical robotic system. The procedure was performed by a renowned urology team at a leading hospital in Hong Kong as part of an ongoing clinical trial.

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The groundbreaking achievement represents a significant milestone in the application of robotic technology for minimally invasive treatment of bladder cancer, offering a promising new surgical option for patients worldwide. Robot-assisted ERBT can enable surgeons to remove bladder tumours in a single piece with greater precision, improving cancer staging accuracy and lowering recurrence rates compared to traditional techniques.

Transforming Bladder Cancer Treatment with Robotic Innovation

The gold standard for early-stage bladder cancer treatment is transurethral resection of bladder tumours (TURBT), which involves removing tumours in a piece-by-piece fashion. However, this traditional piecemeal approach can result in floating tumour cells and incomplete tumour resection, leading to higher recurrence rates and poor cancer staging.

Agilis Robotics’ endoscopic surgical robotic system addresses these challenges with a pair of fully flexible robotic arms that allow surgeons to precisely resect tumours in one piece (i.e. en-bloc). This approach reduces the risk of tumour cell reimplantation, improves specimen integrity for pathological analysis, and significantly decreases the likelihood of cancer recurrence.

Precision, Usability, and Accessibility Redefined

Bladder tumour resections are often complicated by the location of tumours, such as the bladder dome and anterior wall, which are highly challenging to resect completely. The robotic system developed by Agilis Robotics can provide urologists with dexterous and delicate control over the tumour resection process, enabling safer and more precise tumour resection, even in challenging cases.

Agilis Robotics completes world's first robot-assisted bladder tumour resection in clinical trial

Designed with intuitive controls and advanced robotic capabilities, the system can be adopted easily by both experienced surgeons and trainees. By reducing the learning curve for performing ERBT, it has the potential to make this advanced technique more widely available, improving outcomes for patients around the world.

Pioneering Natural Orifice Surgical Robotics

Founded in 2021, the Hong Kong-based Agilis Robotics specializes in developing innovative surgical robots designed to operate through natural orifices such as the urethra, mouth, or anus, eliminating the need for external incisions to treat early-stage tumours.

The company’s robotic system has reached the critical stages of regulatory applications to the FDA and NMPA. If approved, it is poised to become the first commercially available robotic system for transurethral bladder tumour resection.

With its unique technological advantages and significant market potential, the company has secured more than US$17 million in funding, positioning itself as a leader in natural orifice surgical robotics.

Expanding the Boundaries of Minimally Invasive Surgery

The successful demonstration of robot-assisted ERBT not only provides a breakthrough treatment option for bladder cancer but also opens the door to broader applications of minimally invasive robotic surgery through natural orifices, including procedures for the colon and upper gastrointestinal tract.

Agilis Robotics is committed to advancing medical technology, driving innovation, and delivering impactful solutions that benefit patients worldwide.
Hashtag: #agilisrobotics

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LOFTER GROUP Awarded 12 Honors at PropertyGuru Asia Property Awards, Recognized as Best Boutique Developer (Hong Kong and Macau)

UPPER PRINCE Triumphs as Best Connectivity Condo Development in Asia


HONG KONG SAR – Media OutReach Newswire – 20 December 2024 – LOFTER GROUP (“LOFTER” or “the Group”), a Hong Kong-based property developer, is thrilled to announce its recognition at the recently concluded 2024 PropertyGuru Asia Property Awards. The Group has been honored with the Best Boutique Developer (Hong Kong and Macau), while “UPPER PRINCE”, the new residential development of the Group located in Prince Edward, has been recognized with the Best Connectivity Condo Development (Asia). Together with the project at 2C Boundary Street in West Kowloon, the Group has won a remarkable total of 12 awards.

Leveraging exemplary performance in innovative architectural design and distinctive landscape design, both “UPPER PRINCE” and the project at 2C Boundary Street have been honored with multiple awards across several categories, including architectural design, landscape design, and interior design for Hong Kong and Macau. As these significant projects are expected for completion next year, alongside the residential development “Elize PARK” in Mong Kok, the Grade A commercial project “ONE BEDFORD PLACE” in West Kowloon, and the contemporary industrial project “TWO BEDFORD PLACE,” are poised to generate substantial synergistic effects. Collectively, these initiatives are anticipated to rejuvenate the area and transform its overall aesthetic, fostering a vibrant and dynamic environment.

Ms. Carol Chow, Founder and Chairperson of LOFTER said, “we are deeply honored to receive multiple accolades at the PropertyGuru Asia Property Awards for the recognition of our group’s projects. This is an affirmation of the professionalism and dedication to the excellence exhibited by our team. As a local property developer, we are committed to providing high-quality residential projects for the public, while actively preserving the existing cultural heritage and seamlessly integrating into our innovative architectural designs.

We aim to showcase not only the meticulous craftmanship and distinctive advantages of our projects, but also our contribution to the preservation of cultural heritage, thereby achieving sustainable development. ”

List of awards received by the Group is as follows:

LOFTER GROUP

  • Best Boutique Developer (Hong Kong and Macau)


UPPER PRINCE, Prince Edward

  • Best Connectivity Condo Development (Asia)
  • Winner – Best Connectivity Condo Development (Hong Kong and Macau)
  • Winner – Best Condo Architectural Design (Hong Kong and Macau)
  • Winner – Best Condo Landscape Design (Hong Kong and Macau)
  • Highly Commended – Best Condo Interior Design (Hong Kong and Macau)
  • Asia Finalist – Best Condo Architectural Design (Hong Kong and Macau)
  • Asia Finalist – Best Condo Landscape Design (Hong Kong and Macau)


2C Boundary Street, West Kowloon

  • Winner – Best Condo Interior Design (Hong Kong and Macau)
  • Highly Commended – Best Condo Architectural Design (Hong Kong and Macau)
  • Highly Commended – Best Condo Landscape Design (Hong Kong and Macau)
  • Asia Finalist – Best Condo Interior Design (Hong Kong and Macau)

Click here to download HD photos.
Hashtag: #LOFTERGroup #樂風集團 #UPPERPRINCE #PropertyGuru #AsiaPropertyAwards

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LOFTER GROUP

Founded in 2012, LOFTER GROUP is a property developer based in Hong Kong. It is principally engaged in developing exceptional and high-quality residential, commercial, retail, and industrial properties. Leverage on its extensive experience, the Group is actively exploring a variety of opportunities for developing urban renewal projects across core districts of Hong Kong, with key focus on Grade A Commercial and Luxury Residential Projects. The Group vows to accommodate the needs of a diverse market and dynamic social policies, while maintaining a good balance between profitability, responsibility, and sustainability.

Delta Dunia Group Delivers Steady 9M 2024 Results with Transformative Milestones to Fuel Long-Term Growth

  • Despite significant challenges posed by extreme weather conditions in Indonesia and Australia, Delta Dunia Group reported a stable revenue of USD 1.35 billion during 9M 2024.
  • EBITDA for 9M 2024 declined by 16% YoY to USD 252.3 million, impacted by weather-related production declines and planned investments.
  • Net loss significantly improved to USD 17.4 million, down from USD 26.6 million reported in 1H 2024, despite a 20% increase in finance costs and forward-looking investments. A strengthening currency, stable SOFR rates, and ACG’s results – denominated in USD – supported this improvement.
  • Capex increased by 79% YoY to USD 133.1 million, focused on supporting existing site ramp-up and Repair and Maintenance costs. The Group remains on track to meet its full-year capex guidance of USD 150 million to USD 190 million.
  • Operating cash flow increased by 2% YoY to USD 232 million, driven by effective working capital management. The Group’s free cash flow was impacted by strategic investments in ACG and contract-linked Capex.
  • Net Debt to EBITDA maintained at a healthy 2.17x as of September 2024, with acquisitions like ACG expected to improve the ratio.
  • The Group strengthened its operational footprint with significant contracts, including an 11-year, USD 7.8 billion agreement with PT Indonesia Pratama (a Bayan Group subsidiary), a two-year extension at Australia’s Meandu Mine with TEC Coal Pty Ltd, valued at AUD 200 million annually, and a new USD 755 million Life-of-Mine contract with PT Persada Kapuas Prima in Central Kalimantan. These contracts have effectively tripled the Group’s order book to over USD 12.7 billion.
  • The Group also marked pivotal milestones through the transformative acquisitions of ACG, the binding agreement to acquire 51% stakes in the Dawson Complex [1], one of Australia’s largest metallurgical coal mines, and increased investments in 29Metals, an ASX-listed copper-focused base and precious metals mining company.
  • Non-thermal coal revenue is projected to reach 28% by the end of 2024, up from 26% in 9M 2024, aligning with the Group’s strategy to reduce reliance on thermal coal and transition towards a more diversified portfolio.

JAKARTA, INDONESIA – Media OutReach Newswire – 20 December 2024 – PT Delta Dunia Makmur Tbk (“Delta Dunia Group” or “the Group”, IDX: DOID) announced stable results for the first nine months of 2024 (“9M 2024”), forging ahead on its path to sustainable growth in key global markets, demonstrating resilience in its operations and financial performance despite extreme weather conditions and operational challenges. The Group is making significant strides in strengthening its core business and laying a solid foundation for future growth through strategic acquisitions and investments.

In 9M 2024, the Group maintained stable revenue of USD 1.35 billion, compared to USD 1.36 billion year-on-year (“YoY”), despite operational disruptions caused by increased rainfall in Indonesia and Australia, which rose by 38% and 53%, respectively. The effective recovery-after-rain initiative limited the decline in overburden (OB) removal to just 9% YoY, while coal production increased by 3%, demonstrating the effectiveness of its mitigation strategies and operational resilience. The Group’s EBITDA declined by 16.4% YoY to USD 252.3 million, impacted by these extreme conditions and planned investments aimed at enhancing the Group’s long-term production capacity.

The strengthening of the Indonesian Rupiah (IDR) and Australian Dollar (AUD) against the US Dollar (USD), along with a stable Secured Overnight Financing Rate (SOFR), has enabled the Group to manage financial pressures more effectively. In 9M 2024, the Group experienced a 20% YoY increase in finance costs due to forward-looking growth investments, leading to a net loss of USD 17.4 million – a significant improvement from the USD 26.6 million net loss reported in the first half of 2024. It’s important to note that this loss is primarily attributed to proactive measures taken to strengthen the Group’s financial foundation, including early debt repayment and bond buybacks. These actions, while impacting short-term results, are expected to reduce interest expenses and enhance financial flexibility over the long term.

Iwan Fuad Salim, Director at Delta Dunia Group, stated, “9M 2024 marked another pivotal phase in our transformation journey, underscored by major milestones solidifying our path toward sustained growth. Our rigorous focus on operational excellence, geographic expansion, commodity diversification, and sustainability positions us robustly in the global mining landscape. Through strategic acquisitions, significant contract wins, and our further diversification toward non-thermal coal and base metals, we are building a diversified, future-ready business that delivers enduring value for all stakeholders.”

Strategic Investments and Important Contracts Fuel Long-Term Growth

The Group has achieved significant milestones that substantially enhanced its future growth. Key developments include an 11-year, USD 7.8 billion contract extension with PT Indonesia Pratama (IPR), a Bayan Group subsidiary, and a two-year, AUD 200 million annual extension for Australia’s Meandu Mine with TEC Coal Pty Ltd. Additionally, a new USD 755 million Life-of-Mine contract with PT Persada Kapuas Prima (PKP) in Central Kalimantan. These agreements not only spread-out risks but also strengthened the Group’s portfolio’s geographic spread, effectively tripling the Group’s order book to over USD 12.7 billion, reinforcing customer confidence in the Group’s operational capabilities and commitment to long-term partnerships.

The Group also took significant steps to solidify its foundation for sustainable growth through strategic acquisitions. The acquisition of a majority stake in Atlantic Carbon Group, Inc. (“ACG”) marks its entry into the US market, expanding its business into mine ownership. ACG’s financial and performance results, denominated in USD and thereby insulated from foreign exchange risks and currency fluctuations, have been consolidated into the Group’s Q3 2024 results. With the inclusion of ACG’s ultra-high-grade anthracite, non-thermal coal now accounts for 26% of the Group’s revenue, reducing the proportion derived from thermal coal, which currently stands at 74%. Non-thermal coal revenue is projected to reach 28% by the end of 2024.

Moreover, to strengthen its presence as a mine owner, the Group has further entered a binding agreement to acquire a 51% stake in the Dawson Complex, one of Australia’s largest metallurgical coal mines. This high-capacity operation features an annual production capacity of more than 8 million bcm, over 20 years of reserves, and a resource life of 50 years, with a Coal Handling and Preparation Plant (CHPP) capacity surpassing 12 million tons per annum. The Dawson Complex, operational for over 60 years, has fostered strong relationships with key Asian markets, including India and Japan. The Group has also increased its stake in 29Metals Limited, an Australian copper-focused base and precious metals mining company, to advance its diversification into base and precious metals, further reducing its reliance on thermal coal.

Focusing on strategic expansion and diversification, the Group’s capital expenditures reached USD 133.1 million in Q3 2024, marking a 79% increase YoY. These investments enhance operational efficiency and facilitate growth through expansions at existing sites, alongside Repair and Maintenance (R&M) costs that ensure the longevity and efficiency of the Group’s assets, in line with its full-year Capex guidance of USD 150 million to USD 190 million. Simultaneously, improved working capital management led to a 2% increase in operating cash flow, reaching approximately USD 232 million. Free cash flow (FCF) was recorded at USD 80.2 million. However, post-acquisition FCF decreased to USD -35.6 million due to strategic investments, particularly in ACG and contract-linked Capex. These investments represent the Group’s commitment to growth and building a lasting legacy.

Financial Strength and Commitment to Shareholder Value

The Group remains committed to enhancing shareholder value while sustaining a strong financial position through prudent financial management, strategically aligning debt maturity with the lifespan of its operational equipment. As of September 2024, the Group marks a healthy Net Debt/EBITDA ratio of 2.17x. Recent acquisitions, including ACG, are expected to drive improved performance and further strengthen this ratio as ACG’s EBITDA is fully integrated.

The successful issuance of BUMA II 2024 Rupiah Bonds in September 2024, which was 1.4x oversubscribed, demonstrates robust investor demand and confidence in BUMA’s cash flow management and credit profile. This bond issuance has enabled BUMA to secure greater investor commitments for longer-term tenors, significantly enhancing its ability to manage its debt maturity profile effectively.

“We are dedicated to maintaining solid financial management, especially in upholding strong credit metrics and reinforcing our strong presence in the mining sectors in Indonesia, Australia, and the US. The financing strategy we have implemented strengthens our financial foundation and enables us to grow our business, cementing our reputation as a globally diversified mining company,” Iwan concluded.

[1] Subject to Peabody’s acquisition of Dawson, certain pre-emptive rights, consents, and regulatory approvals
Hashtag: #DeltaDuniaGroup

The issuer is solely responsible for the content of this announcement.

About PT Delta Dunia Makmur Tbk (Delta Dunia Group):

Established in 1990, PT Delta Dunia Makmur Tbk (Delta Dunia Group) is a prominent holding company operating in Indonesia, Australia, and the USA. Our principal subsidiary, PT Bukit Makmur Mandiri Utama (BUMA), is a leading provider of mining services to some of the largest miners in Indonesia and Australia (through BUMA Australia Pty Ltd). In June 2024, through PT Bukit Makmur Internasional (BUMA International), it acquired the majority of Atlantic Carbon Group, Inc. (ACG) and became the leading producer of ultra-high-grade anthracite coal in the USA, further strengthening the Group’s global footprint in the mining industry.

In 2023, Delta Dunia Group expanded its portfolio with the addition of two new subsidiaries: PT Bukit Teknologi Digital (BTech), developing AI deep learning technologies to improve operational efficiency, reduce emissions, and minimize Occupational Health and Safety (OHS) operational risks and PT BISA Ruang Nuswantara (BIRU), a social enterprise dedicated to education, vocational schools, and fostering circular economy.

Listed on the Indonesia Stock Exchange (IDX Code: DOID), Delta Dunia Group is headquartered in Jakarta, Indonesia, and is supported by a workforce of over 16,000 employees across Indonesia, Australia, and the USA. In June 2024, Delta Dunia Group was recognized among the Top 200 in the inaugural FORTUNE Southeast Asia 500 rankings, a prestigious list that identifies the region’s largest companies by revenue.

Exchange Plastic for Rewards with 1win and Recycledge


IBADAN, NIGERIA – Media OutReach Newswire – 20 December 2024 – Leading global iGaming brand 1win and non-profit environmental organization Recycledge are thrilled to announce the launch of their collaborative Plastic Waste Exchange (PWE) project—a community-driven initiative to combat plastic waste and promote responsible plastic management in Nigeria.

Plastic Waste Exchange by 1win and Recycledge
Plastic Waste Exchange by 1win and Recycledge

The launch event takes place on December 28, 2024, at IDC School, Old Ife Road, New Gbagi, Ibadan, starting at 10 AM. Members of the public are encouraged to bring their plastic bottles in exchange for vouchers, food items, gifts, or cash rewards. The more kilograms of plastic attendees bring, the more tangible rewards from 1win they will receive.

The event promises to be engaging and fun, with activities including games and entertainment for participants of all ages, exclusive 1win merchandise giveaways, and appearances by renowned Nigerian personalities

Social media influencers Moyin and Doyin Oladimeji (known as @Twinz_Love) and famous Nigerian actor and producer Femi Adebayo will appear on the day to lend their voices to the campaign and inspire community participation.

The PWE project addresses the issue of plastic waste in Ibadan and surrounding areas. Citizens are encouraged to recycle PET bottles by bringing them to 1win-branded PWE stations. With an ambitious goal to collect 5,000 kilograms of plastic waste, 1win and Recycledge aim to send it to recycling sites and prevent plastics from polluting landfills, waterways, and natural habitats in Nigeria.

Following the launch event, 1win-facilitated plastic receptacle stations can be found across Ibadan in the following locations: Ilaji Hotel and Resorts, Hybrid Heights, Agodi Parks and Gardens, and IDC School (New Gbagi).

For more details about the PWE project and event updates, visit www.1win.charity.
Hashtag: #1win #1recycle1win #CSR #recycling


The issuer is solely responsible for the content of this announcement.

About 1win

1win is a leading iGaming brand that offers an unparalleled range of services and is licensed in Nigeria. With a solid seven-year track record, the brand caters to a diverse clientele across the globe, illustrating its strong influence in the iGaming sector. Effective August 2024, 1win has cricketer David Warner as its sports ambassador.

About Recycledge

Recycledge is a Nigerian non-profit organization committed to sustainable waste management solutions, with a focus on plastic waste reduction and recycling education.

Vientiane Economy Hits 5.85 Percent Growth, Beating Expectations

Vientiane Capital (Photo: KPL)

Vientiane Capital’s economy grew by 5.85 percent, surpassing the National Assembly’s initial target of 0.30 percent, according to the city Mayor Atsaphangthong Siphandone. 

AIM Vaccine has obtained clinical approval for two heavyweight products, creating new growth points for performance

HONG KONG SAR – Media OutReach Newswire – 20 December 2024 – AIM Vaccine (06660.HK) has added good news to the research and development of its heavyweight single product. According to the announcement on December 19, the clinical trial approval for the Group’s suspension culture quadrivalent influenza vaccine (MDCK cells) with new technological route and second generation of highly-effective absorbed tetanus vaccine have been recently obtained from the National Medical Products Administration. AIM Vaccine was intensively applied for and won two more clinical trial approvals in this year, creating new growth driver for the company’s future performance.

According to the announcement, currently, all influenza vaccines available on the domestic market are produced using chicken embryo technology. There have not been cell-based influenza vaccines approved for marketing. Compared with the traditional chicken embryo influenza split vaccine, the influenza vaccine (MDCK cells) developed by the Group has been significantly improved in terms of production quality and safety.

The MDCK cells developed by AIM Vaccine has the characteristics of easy cultivation, fast proliferation and susceptibility to influenza virus, etc. By large-scale cultivation of influenza virus in MDCK cells, it can achieve higher production volume, more stable production quality and lower production cost. Furthermore, this product has robust capability to withstand virus mutations, and does not contain ovalbumin, significantly reducing the risk of allergic reactions.

Compared with the influenza vaccines (MDCK cells) developed by other domestic manufacturers, AIM Vaccine adopts the suspension culture method for cell culture, which can be cultivated in bioreactors at scale with low contamination risks and is conducive to large-scale industrial production.

According to the announcement, based on the research and development of the second generation of highly-effective absorbed tetanus vaccine, AIM Vaccine is actively promoting the research and development of diphtheria, tetanus and acellular pertussis – HIB combined vaccine (the “Tetravaccine”), pentavalent vaccine and other multidisease vaccine. Among them, the Tetravaccine is used to prevent invasive infections caused by pertussis, diphtheria, tetanus and Haemophilus Influenzae type b, and has the advantages of reducing the number of vaccinations for infants and young children, and enhancing the vaccination compliance of parents, infants and young children.

The two heavyweight vaccine products announced by AIM Vaccine successfully obtained clinical trial approval documents, and its research and development has entered a new stage. According to the data of China Insights Industry Consultancy Limited, China’s influenza vaccine market will reach approximately RMB20 billion and , the Chinese market size of the multidisease vaccine is expected to reach RMB10 billion in 2030. Therefore, the suspension culture quadrivalent influenza vaccine (MDCK cells) with new technological route and the Tetravaccine will further improve the company’s product pipeline after the market, help enrich the product pipeline, consolidate the industry position, and promote the continued rapid growth of performance.

AIM Vaccine has always focused on unmet clinical needs in key disease areas to advance vaccine development. This year is an intensive year for AIM Vaccine. Up to now, the company has obtained 17 clinical approvals and carried out 21 clinical trials, among which international cutting-edge technology products such as mRNA respiratory syncytial virus (RSV) vaccine (large age group) have also obtained clinical approvals. In addition, the 13-valent pneumonia conjugate vaccine has been accepted, and the serum-free iterative rabies vaccine has also submitted a pre-registration application for listing, and the upcoming blockbuster new product is expected to bring stable revenue growth.
Hashtag: #AIMVaccine

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