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Wired Magazine Founding Editor Kevin Kelly Visits Rokid Headquarters, Exploring the Future of AR and AI

HANGZHOU, China, Oct. 17, 2025 /PRNewswire/ — Kevin Kelly, founding executive editor of Wired magazine, visited Rokid headquarters in Hangzhou for a deep dialogue with Misa Zhu, Founder & CEO of Rokid.


They engaged in a forward-looking conversation on the convergence of artificial intelligence (AI), augmented reality (AR), and the evolution of human-computer interaction. The meeting came as Rokid transitions from a record-setting Kickstarter campaign into a global pre-order phase.

A Meeting Focused on the Future of Technology

During the visit, Kevin Kelly shared his insights on the development of AI and AR, reaffirming his belief that “smart glasses will be the next iPhone” and suggesting that Chinese companies could take the lead in this area.

Misa Zhu presented Rokid’s history, its advancements in AR and AI, and its long-term goal of “Leave Nobody Behind.” The two parties discussed future human-computer interaction models and the worldwide uptake of AR technologies.

At Rokid’s headquarters, Kevin Kelly explored the newest product lineup, including Rokid Glasses, Rokid AR Spatial, and Rokid AR Studio. He praised the company’s technological innovations and its method of integrating virtual interfaces with physical environments.

Dialogue on AI and Human-Computer Interaction

Following the product demonstrations, the participants engaged in an in-depth discussion on key industry topics, including the evolution of AI, the critical moment for AR adoption, and the long-term development cycle of emerging technologies.


Kevin Kelly highlighted that “the future is already here, but unevenly distributed.” He praised Rokid’s forward-looking strategy and perseverance in developing AR and AI technologies, considering these vital steps to make this future accessible to the public.

Misa Zhu stated that Kevin Kelly’s insights have inspired many in the technology industry, noting that “the future Kevin Kelly envisions is what Rokid works to build every day. His visit and recognition provide great encouragement for us.”

Strengthening Shared Belief in AR and AI Integration

The visit facilitates an exchange of ideas between a global technology thought leader and a top AR enterprise. Kevin Kelly’s insights support Rokid’s ongoing belief that the integration of AR and AI will shape the future of human-computer interaction.

Earlier this month, Rokid announced the successful completion of its Kickstarter campaign for Rokid Glasses, which raised more than US$3.6 million from over 5,000 backers, setting a new global record for XR (mixed reality) crowdfunding.

In addition to its global crowdfunding success, Rokid Glasses recently received the “Product of the Year” and “Golden Prize” awards at the 2025 Hong Kong Electronic Industries Awards (EIA) during the Hong Kong Electronics Fair. These awards further reinforce Rokid’s status as a leading innovator in next-generation human-computer interaction technologies and solidify its worldwide leadership in wearable AI and mixed reality applications.


Although the initial campaign has ended, Rokid Glasses are still available for pre-order on Kickstarter. Customers can continue to order through the official campaign page. Although early discounts and bundle deals are no longer available, Rokid continues to accept pre-orders to satisfy ongoing international demand for its AI-enabled AR glasses.

Rokid continues to dedicate itself to advancing AR+AI integration, improving access to Human-Computer Interaction technologies, and fostering innovation that empowers users across various industries and everyday life.

About Rokid

Rokid is a product-oriented platform company with a focus on human-computer interaction for over ten years. As a pioneer in augmented reality, Rokid develops both hardware and software for AR headsets and their surrounding ecosystem, with a mission to ensure that the magic of AI and AR leaves no one behind. With the largest XR developer community in China, its products are consistently regarded among the best wearable devices in the country. It has won the Las Vegas CES Innovation Award for three consecutive years and the German IF Design Award five times.

Website: https://global.rokid.com/ 

Future-Ready Together: CEAT Specialty Partners with Mahindra & Mahindra for OJA Tractor Launch in Australia

  • CEAT Specialty chosen as the preferred OEM tyre partner for Mahindra’s future-ready OJA tractor range in Australia.
  • Range includes tyres for agricultural, industrial and turf applications for the compact and sub compact tractors (20-25 hp range)

BRISBANE, Australia, Oct. 17, 2025 /PRNewswire/ — CEAT Specialty partners with Mahindra & Mahindra’s next-generation OJA tractor range, launched in Australia this September. Mahindra & Mahindra (M&M), the world’s largest tractor manufacturer by volume, unveiled its future-ready OJA series in Brisbane with CEAT as its first-source tyre supplier.

Ahead of the launch, CEAT supplied desired quantities to Mahindra Australia in August 2025. With in-house rim assembly capability at CEAT’s Ambernath facility, the company ensured complete, ready-to-fit solutions for Mahindra’s OJA tractors. The supply covers Farm/Industrial as well as Turf applications, supporting tractors equipped with loaders, backhoes and mowers designed for hobby farming.

CEAT Specialty, already an established brand in the Australian market, has developed tyres precisely engineered to meet the unique demands and challenging terrains of the region. Leveraging its deep understanding of local requirements, CEAT’s engineers worked closely with the M&M team to deliver a meticulously designed range of products tailored for Australian customers.

  • FARMAX – built for superior traction and durability in agriculture.
  • TYROCK Super X3 – designed for industrial strength with loaders and backhoes.
  • TURF XL – ensuring low compaction and smooth turf care for hobby farmers.

Built tough and purpose-driven, Mahindra & Mahindra’s OJA tractors are engineered with robust construction to take on demanding Australian conditions while offering longevity, reliability, and operator comfort. By offering superior traction, durability, and low-compaction performance, CEAT Specialty tyres further strengthen the OJA series, benefiting farmers and hobby users alike

Amit Tolani, Chief Executive, CEAT Specialty, said: “We are proud to partner with Mahindra once again, this time for their future-ready OJA launch in Australia. Our tyres are engineered to deliver performance across industries and applications. This partnership is another step forward in our journey with Mahindra, and a strong example of how CEAT is enabling farmers worldwide with trusted, efficient products.”

Speaking about the partnership, Ravindra S Shahane – Head, Global Product Planning & International Operations (ASEAN & ROW), Mahindra & Mahindra Ltd., commented, “We are proud to introduce the globally acclaimed Mahindra OJA tractor range in an important market like Australia. CEAT Specialty and Mahindra already share a long-standing partnership in the United States, where CEAT has been delivering high performing tyres for farmers. This extension into Australia further strengthens the bond between the two brands, both committed to offering future-ready solutions.”

Setting new standards for Australian farmers and property owners, the OJA range is based on an ergonomic platform with advanced technologies, powerful engine technology and first in segment innovations like button-operated PTO and loader with class-leading lift capacity. The new Mahindra tractors are equipped with features like a digital driver display panel, advanced hydraulics, power steering system and optional cabin configurations – delivering unmatched comfort and control.

With this milestone, CEAT Specialty further cements its position as a global OEM partner of choice, delivering tyres that power some of the world’s most trusted tractor brands.

About CEAT Specialty (www.ceatspecialty.com)

CEAT, an RPG Company, is one of India’s leading tyre companies making passenger car, two-wheeler, truck and bus, light commercial and off highway tyres. It caters to leading OEMs as well as domestic and international markets, exporting to 110+ countries. CEAT is the first tyre brand globally and one amongst only 33 companies in the world ever to be awarded the Deming Grand Prize for its contribution to Total Quality Management. CEAT is also the first tyre brand globally to be accorded ‘Lighthouse Designation’ for adoption of Industry 4.0 technologies by the World Economic Forum. CEAT Specialty is CEAT’s division for off-highway (OTR and Agricultural) tyres.

About RPG Group (www.rpggroup.com)

A US$ 5.2 billion diversified global conglomerate, RPG Group was founded in 1979 by the legendary industrialist Dr R.P. Goenka and has a lineage dating to the early 19th century. Today, its businesses span key sectors of infrastructure, tyres, IT & technology, pharmaceuticals, energy products and plantations among others, with a footprint in over 135 countries. RPG Group’s prominent companies include CEAT, KEC International, Zensar Technologies, RPG Life Sciences, Raychem RPG, Harrisons Malayalam and Spencer International Hotels. The group is home to over 35,000 RPGians from 40 nationalities and is widely recognised for its high standards of corporate governance and a culture of respect for people and the environment.

NYSE Content Advisory: Pre-Market Update + Automakers await 5-year tariff relief extension

NEW YORK, Oct. 17, 2025 /PRNewswire/ — The New York Stock Exchange (NYSE) provides a daily pre-market update directly from the NYSE Trading Floor. Access today’s NYSE Pre-market update for market insights before trading begins. 

 

NYSE Content Advisory: Pre-Market Update + Automakers await 5-year tariff relief extension

Kristen Scholer delivers the pre-market update on October 17th

  • Stocks are lower early Friday after regional bank reports created concerns over bad loans. Loose lending practices pushed traders into safe havens. Activity in the banking sector could inform the Fed’s next decision on interest rates.  
  • Tariff relief is expected for the auto industry after a lobbying push according to reports. The Commerce Department will announce a five-year extension for an agreement that allows carmakers to reduce what they pay in tariffs on car imports.
  • Koom 2025 kicked off yesterday in Brooklyn. The three-day conference celebrates Korean start-up culture, innovation, and K-Pop. Korean business leaders will be in attendance.

Opening Bell
The Breast Cancer Research Foundation highlights its mission to end breast cancer by advancing the world’s most promising research

Closing Bell
National Fallen Firefighters Foundation honors and remembers 176 Fallen Firefighters

Click here to download the NYSE TV App

 

Video – https://mma.prnasia.com/media2/2799213/NYSE_Market_Update_Oct_17.mp4

 

SparkRWA Expands AI Applications to Empower the Global Green Economy and Drive Sustainable Innovation

HONG KONG, Oct. 17, 2025 /PRNewswire/ — GIBO Holdings Ltd. (NASDAQ: GIBO), Asia’s leading innovation-driven creative ecosystem, today announced an extended application of its proprietary AI technologies under the SparkRWA Green Creator Framework, marking a major step toward integrating artificial intelligence into the green economy and sustainable development sectors.

This strategic expansion reinforces GIBO’s commitment to bridge creativity, technology, and environmental responsibility — using AI to measure, optimize, and accelerate sustainable transformation across industries.

Extending AI from Creative Innovation to Green Transformation

Building upon the success of its AIGC-powered platforms, including GIBO.ai and GIBO Click, GIBO is now extending its core AI capabilities into green infrastructure intelligence, eco-design optimization, and sustainability verification.
The goal is to empower creators, innovators, and enterprises to integrate measurable sustainability into their projects — from content production and storytelling to technology development and energy solutions.

The upgraded SparkRWA Green Framework now enables:

  • AI-Powered Environmental Analytics — Leveraging machine learning to assess the efficiency and environmental impact of products, projects, or creative outputs.
  • Smart Energy & Design Optimization — AI models that simulate and refine processes to reduce waste, emissions, and energy consumption.
  • Impact Measurement & Verification — Automated evaluation of sustainability indicators, supporting organizations in achieving data-driven ESG reporting and compliance.
  • Creative Integration with Sustainability — Encouraging filmmakers, designers, and innovators to embed environmental narratives into their work using AI-assisted creative tools.

“AI is no longer just a creative tool — it’s a transformative instrument for sustainability,” said Zelt Kueh, CEO of GIBO Holdings Ltd.
“Through SparkRWA, we are extending GIBO’s AI systems beyond content creation into the green economy, ensuring that innovation can be both intelligent and responsible.”

Laying the Foundation for a Smart and Measurable Green Economy

SparkRWA’s AI-driven ecosystem plays a crucial role in establishing a data-backed sustainability framework that can be applied across renewable energy, mobility, and environmental design sectors.
The initiative enables businesses and creators to quantify their contributions to carbon reduction, resource efficiency, and circular innovation — aligning creativity with measurable green impact.

Early focus areas include:

  • Renewable Energy Intelligence: AI-assisted analysis and visualization of solar, wind, and hydrogen project performance.
  • Sustainable Production Systems: Smart AI scheduling and optimization tools to reduce energy consumption and material waste.
  • Green Storytelling & Media: Empowering short film creators and digital platforms to promote awareness of sustainability and climate innovation.

Bridging AI Innovation with Real-World Sustainability

SparkRWA represents a strategic evolution of GIBO’s ecosystem from AI-generated content toward AI-applied sustainability.
The initiative aligns with GIBO’s long-term vision to empower industries with AI that can understand, measure, and improve the environmental performance of real-world operations — laying the groundwork for AI-integrated renewable systems, smart cities, and green mobility solutions.

About GIBO Holdings Limited

GIBO Holdings Ltd. is a unique and integrated AIGC animation streaming platform with extensive functionalities provided to both viewers and creators that serves a broad community of young people across Asia to create, publish, share and enjoy AI-generated animation video content. With over 83 million registered users and advanced AI-powered tools, GIBO seeks to redefine the landscape of digital content creation.

Forward-Looking Statements

This press release includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as “estimate,” “plan,” “project,” “forecast,” “intend,” “will,” “expect,” “anticipate,” “believe,” “seek,” “target” or other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements also include, but are not limited to, statements regarding projections, estimates and forecasts of revenue and other financial and performance metrics, projections of market opportunity and expectations, the Company’s ability to scale and grow its business, the Company’s advantages and expected growth, the Company’s ability to source and retain talent, and the Company’s cash position, as applicable. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the Company’s management and are not predictions of actual performance. These statements involve risks, uncertainties and other factors that may cause the Company’s actual results, levels of activity, performance, or achievements to be materially different from those expressed or implied by these forward-looking statements. Although the Company believes that it has a reasonable basis for each forward-looking statement contained in this press release, the Company cautions you that these statements are based on a combination of facts and factors currently known and projections of the future, which are inherently uncertain. The forward-looking statements in this press release represent the views of the Company as of the date of this press release. Subsequent events and developments may cause those views to change. Except as may be required by law, the Company does not undertake any duty to update these forward-looking statements.

Contact Information
Investor Relations:
Bill Zima
ICR, Inc.
William.zima@icrinc.com 

Media Relations:
Edmond Lococo
ICR, Inc.
Edmond.Lococo@icrinc.com

For more information and the latest updates, please visit:
 https://www.globalibo.com/gibo-click/

Re-imagining Neo-Pragmatic Lifestyle: EPWK Launches Strategic Upgrade with “EPWK Curated Goods”

XIAMEN, China, Oct. 17, 2025 /PRNewswire/ — “We grew weary of life’s monotony, so we embarked on a journey to find ‘EPWK Curated Goods.’ Each selected item must pass our stringent ‘Three Goods’ standard: Good-looking, Good-to-use, and Good-surprise. We believe that truly excellent products can illuminate every ordinary day.”

EPWK (stock code: EPWK), the first Chinese concept stock in creative design on the NASDAQ Global Market, that the company will launch a Chinese and English e-commerce platform for “EPWK Curated Goods” – a creative physical product marketplace – within the next three months.

Positioned as the “Wellspring of Neo-Pragmatic Living,” EPWK Curated Goods focuses on discovering and providing creative physical products that possess a trifecta of outstanding design, practical function, and emotional resonance. Its mission is to upgrade the ordinary routine of modern consumers who pursue quality of life into an experience filled with surprise and aesthetic delight.

In an era of highly developed material supply, consumers’ basic needs are fully met. The prevailing dilemma is no longer “can I buy it?” but rather the decision-making struggle of “what is truly worthwhile?” Concurrently, a consumption tendency that prioritizes emotional value and aesthetic expression—known as “Neo-Pragmatism”—is gradually becoming the core lifestyle philosophy of the younger generation. They expect products to not only fulfill their functions but also convey attitude, inspire resonance, and serve as an extension of their personal lifestyle.

Based on this profound insight into the trend, EPWK views the launch of the EPWK Curated Goods project as a crucial strategic upgrade—transitioning from a creative service ecosystem to the direct shaping of consumer lifestyles. Specifically, the future English version marks the starting point for building a global brand ecosystem.

Xiamen EPWK Network Technology Co., Ltd. (EPWK) was founded in March 2011. It is China’s leading digital and intelligent creative transaction service e-commerce platform and the first “Chinese Crowdsourcing Platform Stock” to be listed on the NASDAQ Global Market in the United States.

As of June 30, 2024, the platform has accumulated over 25.66 million registered users. Between 2019 and June 30, 2024, a total of 4.6 million projects were completed, with Gross Merchandise Volume (GMV) exceeding USD $1.67 billion.

The profound resources and brand credibility the company has accumulated in the creative service industry will provide strong support for the product selection logic and supply chain construction of “EPWK Curated Goods.”

From “Tool” to “Companion”: The Evolution of Consumer Values

In the traditional sense, “utility” focuses on a product’s basic functional attributes, with its core purpose being to solve specific problems. However, for Generation Z and Millennials, who have become the dominant consuming force, the value of goods is expanding from a single functional dimension to encompass emotional connection and aesthetic expression.

This demographic grew up in an era of rapid economic development and high internet penetration, and they are accustomed to constructing their self-identity within an environment of information overload. Built upon a foundation of material affluence, they are more eager to achieve spiritual satisfaction and identity recognition through their consumption behaviors.

Specifically, their consumer motivation is reflected in two key dimensions:

Firstly, at the level of “Emotional Utility,” the product’s role shifts from a tool to a companion. For instance, an alarm clock used merely for waking up is functionally no different in essence from a wake-up light that simulates sunrise and plays natural sounds. However, the latter offers the user a more caring experience, establishing an emotional connection that transcends mere function. This concept of “Emotional Utility” is precisely the core screening criterion for “EPWK Curated Goods.”

As Feng Mei, EPWK’s Head of Product Technology, stated, the “utility” defined by EPWK Curated Goods is not limited to the satisfaction of basic needs. She provided an example: a cup that is both ergonomically designed and equipped with a starry sky projection function on its base not only serves the physical need for drinking but also provides companionship and comfort on a spiritual level, achieving the unity of “Functional Utility” and “Emotional Utility.”

Secondly, at the level of “Aesthetic Utility,” a product’s exterior design and aesthetic expression itself become a form of social capital and status symbol. In a highly visual communication environment, high-aesthetic products not only enhance the user experience but also serve as an important medium for users to showcase their personal taste and lifestyle. For example, a cleverly designed portable coffee cup, while ensuring practicality, has an appearance that acts as a stylish accessory during the user’s daily commute, reinforcing their identity as an “urban explorer.”

The Differentiated Path of “EPWK Curated Goods”: Building Lifestyles with a Curatorial Mindset

Based on a profound insight into contemporary consumer culture, “EPWK Curated Goods” does not position itself as a generic creative product sales channel. Instead, it aims to become a trusted “Lifestyle Curator,” precisely addressing the market gap between mass e-commerce platforms and high-end concept stores.

In its positioning, “EPWK Curated Goods” explicitly rejects the industry status quo characterized by a combination of cheapness and inaccessibility. Compared to the widespread product homogenization problem found in the creative channels of large e-commerce platforms, and the prohibitive pricing of high-end design concept stores, “EPWK Curated Goods” advocates establishing a balance between the two. It focuses on providing goods that are “acceptably priced, cleverly designed, and well functional,” precisely matching the Neo-Pragmatist consumer’s comprehensive demand for quality, value, and design aesthetics.

In its model, “EPWK Curated Goods” builds a trust mechanism with “curation” at its core. Against the backdrop of information overload, user attention and trust have become scarce resources. “EPWK Curated Goods” employs a stringent screening process by a professional team, selecting products from a massive pool based on the “Three Goods” standard: Good-looking, Good-to-use, and Good-surprise. This allows users to reduce their decision-making costs, transforming the shopping process from tedious information filtering into an enjoyable discovery of inspiration. Users are choosing not just the product itself, but the aesthetic guarantee and selection professionalism provided by “EPWK Curated Goods.”

In terms of user experience, “EPWK Curated Goods” is committed to upgrading from a transactional marketplace to a source of inspiration. “EPWK Curated Goods” does not only provide product transaction functions but also guides users to re-imagine their daily life scenarios through themed and contextualized content curation—such as featured topics like “Ten Small Items to Boost Home Happiness” or “Perfect Gifts for Creative Professionals.” Under this logic, consumption is no longer the end point, but the starting point for achieving a higher quality of life and emotional satisfaction.

Core User Profile: Aligning with the Values of the “Urban Life Explorer”

“EPWK Curated Goods” defines its core user as the “Urban Life Explorer” aged 25 to 40. This demographic is primarily concentrated in first- and second-tier cities, represented by white-collar professionals, creative workers, teachers, and young managers. They generally possess good educational backgrounds and stable middle-to-higher income levels. They not only have the willingness and ability to pay for emotional and aesthetic value but also regard consumption as a crucial way to construct identity, resist repetition, and seek belonging.

In terms of identity recognition, in highly atomized urban life, individual consumption choices become a crucial way of self-definition. A designer speaker or a set of eco-friendly tableware is not merely a practical object; it is an external expression of personal taste and values. The high-quality, highly recognizable products offered by “EPWK Curated Goods” are thus becoming powerful tools for users to build and reinforce their self-identity.

In terms of emotional appeal, the fast-paced, high-pressure urban life can easily lead individuals into a state of repetition and numbness. The brand proposition, “EPWK Curated Goods, Illuminating Daily Surprises,” is precisely a response to this emotional pain point. Those products possessing the “Good-surprise” attribute, such as a starry sky projection at the bottom of a cup or a brightly colored ergonomic chair, inject novelty and poetic moments into the user’s life in small yet tangible ways.

In terms of social interaction, as KOL active on social networks, this demographic enjoys sharing and seeking like-minded individuals. The unique products sourced from “EPWK Curated Goods” can serve both as effective conversation starters in social interactions and as “non-clash” gift choices that precisely convey heartfelt intentions. Consumption behaviors rooted in shared aesthetics and values further reinforce the sense of belonging and identity within their social circles.

Neo-Pragmatism: A Rational Expression of a Lifestyle Philosophy

“Neo-Pragmatism” fundamentally represents a contemporary life attitude: rational yet warm, practical yet aesthetic. It reflects people’s legitimate desire for aesthetic experience and emotional resonance, built upon the foundation of pursuing efficiency and function.

Leveraging the profound heritage accumulated by EPWK over more than a decade in the creative ecosystem, “EPWK Curated Goods” serves as the materialized embodiment of this lifestyle attitude. “EPWK Curated Goods” does not encourage aimless consumption; rather, it advocates for a smarter, more conscious way of living, ensuring that every purchase acts as a positive vote for an ideal life and a gentle revolution against daily mediocrity.

Behind this lifestyle philosophy lies the deep synergy between “EPWK Curated Goods” and the EPWK ecosystem. As a natural strategic extension, “EPWK Curated Goods” can directly interface with the massive pool of designers and creative agencies aggregated on the platform. This not only provides a continuous source of innovation for the products but also establishes a unique “Creator Economy” loop. Simultaneously, data feedback from the consumer end will feed back into the creative platform, helping creators accurately grasp market demand, forming a closed-loop of growth that moves from creation to consumption, and then back to driving creation. This is not just product curation; it is the vivid realization of EPWK initiating a strategic upgrade with “EPWK Curated Goods,” dedicated to reimagining the Neo-Pragmatic lifestyle.

Consumers are choosing not just products with excellent designs, but the lifestyle philosophy they represent. To trust “EPWK Curated Goods” is to endorse a belief: that truly “good products,” beyond their functional attributes, should carry human emotion, express human individuality, and illuminate daily life. This is the profound logic of “Useful, and Must Be Meaningful,” and it is the new consumption philosophy that this era is jointly writing.

Kelun-Biotech’s Core product Trastuzumab Botidotin Approved for Marketing by NMPA for HER2-positive BC

CHENGDU, China, Oct. 17, 2025 /PRNewswire/ — Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (the “Company”) announced that the Company’s human epidermal growth factor receptor 2 (HER2)-directed antibody-drug conjugate (ADC) trastuzumab botidotin (also known as A166)  was approved for marketing by the National Medical Products Administration (NMPA) for the treatment of adult patients with unresectable or metastatic HER2-positive breast cancer (BC) who have received one or more prior anti-HER2 therapy.

The approval is based on a multi-center, randomized, open-label, controlled, Phase 3 KL166-III-06 study that evaluates the efficacy and safety profile of trastuzumab botidotin versus T-DM1 in patients with HER2-positive unresectable or metastatic BC who have received prior trastuzumab and taxane-containing regimens. At a pre-specified interim analysis, trastuzumab botidotin monotherapy demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint of progression-free survival (PFS) as assessed by the blinded independent central review (BICR) compared with T-DM1; the beneficial trend for overall survival (OS) of trastuzumab botidotin was also observed. Results from this study will be presented as an oral report at the 2025 European Society for Medical Oncology (ESMO) Congress held in Berlin, Germany (Presentation # LBA24, Proffered paper session 1: Breast cancer, metastatic).

The Company has initiated an open, multi-center Phase 2 clinical study of trastuzumab botidotin in the treatment of HER2+ unresectable or metastatic BC that previously received a topoisomerase inhibitor ADC.

Dr. Michael Ge, CEO of Kelun-Biotech said, “We are thrilled to see our first HER2 ADC drug, trastuzumab botidotin, successfully approved for market. This marks a significant advancement in the treatment of HER2-positive breast cancer. As China’s first domestically developed HER2 ADC capable of broadly covering 2L+ HER2 BC patients, trastuzumab botidotin leverages its differentiated structural design to deliver superior efficacy while addressing unmet clinical needs in this population.”

About HER2+ BC

Breast cancer, as the most common malignant tumor, poses a serious threat to women’s health. Among its subtypes, HER2-positive breast cancer accounts for approximately 15%–20% of all breast cancer cases[1], and is characterized by its aggressiveness and high malignancy. According to the 2025 CSCO guidelines, first-line treatment for HER2-positive breast cancer primarily consists of trastuzumab and pertuzumab in combination with taxane-based chemotherapeutic agents. Second-line treatment regimens comprise tyrosine kinase inhibitors (TKIs, such as pyrotinib) and antibody-drug conjugates (ADCs, such as T-DM1 and T-DXd). Following disease progression on second-line therapy, subsequent treatment strategies are determined based on prior second-line regimens, the patient’s tolerance to therapy, tumor burden, and other relevant factors. Despite recent advances in anti-HER2 therapeutics, a significant number of patients still experience drug resistance or severe adverse effects, highlighting an urgent need for agents with improved safety profiles to address the treatment requirements of patients with recurrent or drug-resistant HER2-positive breast cancer.

About trastuzumab botidotin

Trastuzumab botidotin is a differentiated HER2 ADC to treat advanced HER2+ solid tumors. As an innovative HER2 ADC developed by the Company, it conjugates a novel, monomethyl auristatin F (MMAF) derivative (a highly cytotoxic tubulin inhibitor, Duo-5) via a stable, enzyme-cleavable linker to a HER2 monoclonal antibody with a drug-to-antibody-ratio (DAR) of 2. Trastuzumab botidotin specifically binds to HER2 on the surface of tumor cells and is internalized by tumor cells, releasing the toxin molecule Duo-5 inside the cell. Duo-5 induces tumor cell cycle arrest in the G2/M phase, leading to tumor cell apoptosis. After targeting HER2, trastuzumab botidotin can also inhibit the HER2 signaling pathway; it has antibody-dependent cell-mediated cytotoxicity (ADCC) activity.

About Kelun-Biotech

Kelun-Biotech (6990.HK) is a holding subsidiary of Kelun Pharmaceutical (002422.SZ), which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. The company focuses on major disease areas such as solid tumors, autoimmune, inflammatory, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. The Company is committed to becoming a leading global enterprise in the field of innovative drugs. At present, the Company has more than 30 ongoing key innovative drug projects, of which 4 projects have been approved for marketing, and more than 10 projects are in the clinical stage. The company has established one of the world’s leading proprietary ADC and novel DC platforms, OptiDC™, and has 2 ADC projects approved for marketing, and multiple ADC and novel DC assets in clinical or preclinical research stage. For more information, please visit https://kelun-biotech.com/

Reference:

[1]. CRONIN K A, HARLAN L C, DODD K W, et al. Population-based estimate of the prevalence of HER2-positive breast cancer tumors for early stage patients in the US [J]. Cancer Invest,2010, 28(9): 963-968. DOI: 10.3109/07357907.2010.496759.

 

Bybit x Block Scholes Quarterly Report: Rise of Perp DEXs — and How to Catch the Opportunity

DUBAI, UAE, Oct. 17, 2025 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, has released its latest Bybit x Block Scholes Crypto Derivatives Analytics Report.

Key Highlights:

  • Perp DEXs surge in adoption: Decentralized perpetual exchanges (perp DEXs) have seen explosive growth since late 2024, reshaping the trading landscape with speed, accessibility, and on-chain transparency.
  • Hyperliquid dominates: Hyperliquid captured 58% of trading volume across the top eight perp DEXs in 2025, with daily fee generation consistently outpacing Uniswap since May. The exchange has contributed up to 60% of total fees across major blockchains.
  • Why traders are migrating: Traders are shifting from centralized exchanges (CEXs) and spot DEXs to perp DEXs due to frictionless onboarding, self-custody, faster token listings, competitive fee structures, and leverage up to 100x.
  • HYPE token performance: Hyperliquid’s native token, HYPE, has surged more than six-fold since April 2025, supported by a 97% revenue buyback program. However, a major token unlock beginning November 29, 2025, could dilute this momentum unless buybacks scale further.

Perp DEXs are increasingly viewed as the next frontier in crypto trading, offering a blend of speed, security, and transparency that rivals traditional centralized platforms. With traders prioritizing autonomy and efficient market access, the shift toward decentralized perpetual trading has accelerated throughout 2025.

The report underscores how Hyperliquid’s innovative tokenomics, user-friendly design, and liquidity incentives have positioned it as a frontrunner in this sector. However, with challenges such as liquidity fragmentation and upcoming token unlocks, the market remains dynamic, presenting both opportunities and risks for traders and investors alike.

The full analysis is available in the Bybit x Block Scholes Crypto Derivatives Analytics Report.

#Bybit / #CryptoArk /#BybitResearch / #BybitLearn

About Bybit

Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving a global community of over 70 million users. Founded in 2018, Bybit is redefining openness in the decentralized world by creating a simpler, open and equal ecosystem for everyone. With a strong focus on Web3, Bybit partners strategically with leading blockchain protocols to provide robust infrastructure and drive on-chain innovation. Renowned for its secure custody, diverse marketplaces, intuitive user experience, and advanced blockchain tools, Bybit bridges the gap between TradFi and DeFi, empowering builders, creators, and enthusiasts to unlock the full potential of Web3. Discover the future of decentralized finance at Bybit.com.

For more details about Bybit, please visit Bybit Press
For media inquiries, please contact: media@bybit.com
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Patented Innovation Empowers Home Creators Delivering Professional Customization with Simplified Operation and Friendly Pricing

NEW YORK, Oct. 17, 2025 /PRNewswire/ — VEVOR, a leading home improvement brand empowering home creators worldwide, announced the launch of its Hybrid Heat Press, a patented heat transfer machine designed to make professional-grade customization accessible to young creators, DIY enthusiasts, and small business owners. Combining simplified operation with competitive pricing, the Hybrid Heat Press delivers professional results without the complexity or cost of traditional equipment.

Three Steps to “Set It and Forget It” Experience: Simplified Professional Pressing

The Hybrid Heat Press features a 3-step operation designed to create a “set it and forget it” workflow. This approach addresses a common pain point in heat pressing: the physical effort and constant attention required throughout the pressing process.

Picture a young designer working on custom streetwear in studio. With the Hybrid Heat Press, the process is intuitive:Step one—pull out the smooth-gliding press board. Step two—place the design and fabric, then push to position. Step three—one pull of the handle activates 170kg of consistent pressure. Once these three steps are complete, the machine takes over. The user can walk away to prep their next project while the press works – a true “set it and forget it” experience.

Bridging Manual and Automatic: Performance Meets Friendly Price

The Hybrid Heat Press is available in two press sizes: 15″x15″ and 12″x15″. It can be easily stored in a closet when not in use or displayed on a desk without dominating the room. The multi-functionality options include 5-in-1 and 8-in-1 configurations, allowing users to customize not only T-shirts but also caps, mugs, plates, and other items with a single machine.

Temperature control ranges from 150-240℃ with a digital display, giving users precise command over diverse materials—from cotton tees to technical fabrics like polyester blends and performance wear. This range means a creator can press a vintage-style design onto a soft cotton sweatshirt in the morning, then switch to sublimation on a synthetic sports jersey in the afternoon, all under the same machine.

The maximum opening height of 50mm addresses a limitation that often frustrates creators using entry-level presses: the inability to work with thicker items. The Hybrid Heat Press accommodates hoodies, layered garments, and even household textiles like blankets and tote bags. For a small business owner, this translates to more diverse product offerings. The message is clear: don’t let your tools limit your creativity.

Safety features include a full pull-out design that keeps users’ hands away from the heat plate, preventing burns during operation. The 15-minute auto shut-off function protects against fire hazards if users forget to turn off the machine. The Hybrid Heat Press works with various materials including PUFF HTV, DTF transfers, sublimation, and other heat transfer mediums, providing versatility for different creative projects.

The robust frame structure features dual-column support that ensures the press maintains its 170kg pressure capacity without bending or deforming, even with extended use. This consistent pressure delivery is what separates the Hybrid Press from manual swing-away models, where pressure consistency depends entirely on user strength and technique.

For years, creators faced an uncomfortable choice—struggle with unreliable manual equipment that demands constant physical effort and produces inconsistent work, or invest $400+ in an automatic press that may exceed their budget. VEVOR’s patented design removes this trade-off centered on its patented design, covering both its core features and its unique external appearance. Users get the reliability and hands-free convenience they need—consistent pressure, automated operation, the ability to walk away—without the budget barrier.

Meeting the Moment: Responding to Market Trends

The Hybrid Heat Press launch comes at a pivotal moment for home creativity. From young creators designing custom streetwear to families making matching themed apparel for backyard gatherings, the demand for accessible customization tools continues to grow. Small business owners are building online shops around personalized merchandise, while DIY enthusiasts craft meaningful one-of-a-kind gifts that can’t be found in stores.

“We’re seeing a rise in DIY culture and demand for affordable creative tools, especially among younger generations,” said Gavin, Brand Director. “The customization market is thriving, but many creators have been priced out of quality equipment or intimidated by complex machinery. We developed the Hybrid Heat Press to remove those barriers.”

VEVOR’s brand positioning centers on “Upgrade your stories—the home creator way to unleash your personality.” This ethos explains the company’s focus on younger generations, who actively seek authentic channels for self-expression. Whether through street art, custom fashion, or personalized home décor, young creators want tools that help them tell their unique stories without creative or financial constraints. The Hybrid Heat Press embodies this vision—providing an accessible, high-performance avenue for turning ideas into tangible expressions of identity.

This product also exemplifies VEVOR’s broader mission of democratizing premium home ecosystems through vertical integration and accessible pricing. Since 2007, VEVOR has been dismantling price barriers in home improvement, enabling customers to transform their spaces without compromise. This reflects VEVOR’s commitment to supporting the “Home Creator” community—those who actively reshape their living spaces to express their inner pursuits and find joy in turning visions into reality with their own hands.

The VEVOR Hybrid Heat Press is available now through vevor.com, Amazon and a few other authorized channels, with pricing starting at $189.9 for the 12″x15″ 5-in-1 model and $239.9 for the 15″x15″ 8-in-1 model.

About VEVOR

VEVOR is a global home improvement brand that empowers home creators, who actively reshape living spaces to express their inner pursuits, finding joy in turning visions into reality with their own hands to upgrade spaces with pro-level gear at fair prices. From backyard makeovers to apartment innovations, VEVOR delivers uncompromised quality through vertical integration—combining precision engineering with the joy of making.

Founded in 2007 as an eBay seller, VEVOR began selling on Amazon in 2013 and launched vevor.com in 2020. The brand unveiled its refreshed identity in 2025. Today, VEVOR operates in over 50 countries, with a network of 200+ global warehouses and a catalog of over 40,000 products spanning tools, outdoor equipment, and home improvement solutions.

The brand’s promise is built on four pillars: professional-grade performance, unexpected value, complete home ecosystem coverage, and uncompromising quality. This commitment is reflected in its 90% customer satisfaction rate, supported by 24/7 assistance and a 30-day hassle-free return policy.

For more information, visit vevor.com or search “vevor” on Amazon.

Media Contact: VEVOR Communications Team media@vevor.com