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Google AI Breakthrough Highlights Silmitasertib (CX-4945) as a Novel Pathway in Cancer Immunotherapy

TAIPEI and SAN DIEGO, Oct. 21, 2025 /PRNewswire/ — Senhwa Biosciences’s investigational new drug Silmitasertib (CX-4945) was recently featured in an official post by Google DeepMind, following a major breakthrough by the tech giant’s biological artificial intelligence (AI) system.

DeepMind reported that its latest AI model successfully generated and experimentally validated a new hypothesis for cancer treatment, calling it “a milestone for AI in science.” Through large-scale analysis of tumor cell data and more than 4,000 potential drug candidates, DeepMind’s model identified CX-4945 as a key molecule that significantly enhances antigen presentation—a crucial process that enables the immune system to recognize and attack tumor cells.

This groundbreaking finding suggests that CX-4945 could unlock a new therapeutic direction in cancer immunotherapy, potentially transforming how “cold tumors”—those invisible to immune cells—can be converted into “hot,” immune-responsive ones.

AI-Driven Biomedical Innovation: Turning Cold Tumors Hot

Google CEO Sundar Pichai wrote on X (formerly Twitter), “With further preclinical and clinical testing, this discovery could reveal a promising new avenue for developing anti-cancer therapies.”

Developed in collaboration with Yale University, DeepMind’s C2S-Scale model, built on the Gemma architecture and comprising 27 billion parameters, successfully predicted that inhibiting protein kinase CK2 with CX-4945 could significantly increase MHC-I expression and antigen presentation—a concept never previously documented in scientific literature.

Follow-up laboratory studies confirmed these hypotheses: when human neuroendocrine cells were treated with CX-4945 and low-dose interferon, antigen presentation increased by approximately 50%, making tumor cells more visible to immune attack.

Silmitasertib Recognized in DeepMind’s Research Findings

Silmitasertib (CX-4945) is Senhwa’s first-in-class CK2 inhibitor, currently under clinical development across multiple cancer indications. To date, the compound has been administered to hundreds of patients worldwide, demonstrating a favorable safety profile and encouraging efficacy signals.

In the United States, CX-4945 has been selected by the Beat Childhood Cancer Research Consortium and is now being evaluated in collaboration with the Penn State Health Children’s Hospital for the treatment of relapsed pediatric solid tumors.

Being identified and validated by Google DeepMind’s advanced AI platform not only strengthens the scientific foundation of CX-4945, but also highlights its strategic potential in the next generation of cancer immunotherapies.

A New Era of AI-Enabled Drug Discovery

DeepMind researchers noted that scaling biological AI models not only enhances prediction accuracy but also enables the generation of entirely new, testable scientific hypotheses. This integration of AI-driven simulation with experimental validation represents a new paradigm for biomedical discovery and drug development.

Although this research remains in the preclinical stage, it marks a transformative moment for the intersection of artificial intelligence and medicine. Senhwa believes that, through continued collaboration between AI innovation and clinical science, CX-4945 could accelerate its path toward becoming a breakthrough immuno-oncology therapy that benefits cancer patients globally.

As Taiwan’s biopharmaceutical innovation gains international recognition, Senhwa aims for its CX-4945 program to stand alongside the nation’s semiconductor success — becoming a new “National Shield” for global health.

News source:
https://blog.google/technology/ai/google-gemma-ai-cancer-therapy-discovery/

Vegatron Unveils Next-Gen Fuel Management Software in Singapore, Accelerating Digital Transformation in Oil and Gas


SINGAPORE – Media OutReach Newswire – 21 October 2025 – Vegatron Pte Ltd, a Singapore-based leader in oil and gas distribution and speciality lubricants, is strengthening its technology roadmap through the ongoing advancement of its Vegatron V-7 Smart Technology System, a proprietary fuel management software built from scratch as a long-term strategy to drive sustainable efficiency, informed decision-making, and seamless operations.

Vegatron Diesel Truck
Vegatron Diesel Truck

Empowering Businesses Through Technology

The Vegatron V-7 Smart Technology System combines real-time data, automation, and secure cloud-based access to help businesses manage orders, accounts, and reports with greater efficiency. As a comprehensive fuel management software, it supports digital invoicing, e-signature authorisations, and centralised dashboards that improve visibility and operational control.

Designed with usability in mind, the platform allows users to automate recurring workflows and consolidate financial and operational data within a single system. Its flexibility suits businesses of all sizes, helping them optimise refuelling services, monitor consumption patterns, and enhance productivity through a connected, data-driven process.

From Fuel Supplier to Digital Innovator

Vegatron has grown from a trusted fuel supplier in Singapore into a forward-looking company that integrates digital solutions within the energy sector. The introduction of the V-7 fuel management software marked a significant step in this evolution, providing businesses with a comprehensive smart operations platform that enables efficient order management, real-time tracking of usage, and streamlined administrative workflows.

This strategic shift reflects Vegatron’s belief that innovation must be built in-house to ensure long-term adaptability and continuous improvement. By creating the V-7 Smart Technology System from the ground up, the company has developed more than just a management application; it has established a framework for future digital growth in the energy industry.

Driving Digital Transformation in the Oil and Gas Industry

Vegatron’s continued development of V-7 reflects its broader vision for digital transformation in the oil and gas industry. By integrating automation into fuel and lubricant management, the company is bridging conventional energy operations with modern business automation technology. The continuous improvement of the Vegatron V-7 Smart Technology System signals Vegatron’s intent to introduce new capabilities to the industry and maintain a culture of iterative product enhancement.

Chief Executive Officer Mr Daniel Koh stated, “The V-7 system demonstrates how technology can simplify daily operations while supporting sustainability goals. Our objective is to develop digital solutions that enable businesses to manage resources efficiently and make informed decisions in an increasingly competitive environment.”

Commitment to Sustainability and Efficiency

The development of Vegatron’s fuel management software supports more sustainable business practices. Features such as digital invoicing and e-documentation help reduce paper usage while improving operational efficiency and transparency. Streamlined processes also support cost savings and stronger data security for clients.

Vegatron remains committed to reducing greenhouse gas emissions within its own operations and across its network of partners. The company’s ongoing enhancements to the Vegatron V-7 Smart Technology System demonstrate a sustained commitment to modernising energy workflows while upholding the reliability and service standards expected of leading oil and gas trading companies in Singapore.Hashtag: #vegatron #oil&gas #fueldistributor #dieselsupplier

The issuer is solely responsible for the content of this announcement.

About Vegatron

Vegatron Pte Ltd is a Singapore-based company specialising in the distribution of petroleum and speciality lubricants. As a trusted , Vegatron provides reliable products and technology-driven solutions that enhance operational efficiency across diverse industries. Guided by its mission to bring digitisation to the fuel and lubricant sector, the company develops proprietary tools, such as the Vegatron V-7 Smart Technology System, to simplify operations and support sustainability.

For more information, visit .

MAY ZHOU, Chairwoman of School Board of KL International School of Chongqing Bashu: A Decade of Dedication — “A Responsive School for A Changing World”

CHONGQING, China, Oct. 21, 2025 /PRNewswire/ — In 2015, KL International School of Chongqing Bashu (KLIS) was officially established, introducing authentic American education to Southwest China. Over the past decade, the school has grown into an important AP, SAT, PSAT, and ISEE testing center, earned Cognia accreditation—the world’s largest education accreditation organization—and risen steadily in the Forbes China International Schools Ranking.

How was this remarkable success achieved step by step? On the occasion of the school’s 10th anniversary, May Zhou, Chairwoman of the School Board, shared her reflections on this extraordinary journey.

A Journey Rooted in the Original Aspiration of Education

“Ten years ago, what we had in front of us was almost a blank canvas—just three students, a few passionate teachers, and one school building,” May Zhou recalled vividly. The beginnings were humble, but the conviction was firm—to build a school that truly prepares children for a rapidly changing world.

“In Chinese culture, the number ‘three’ symbolizes infinity—’one gives birth to two, two gives birth to three, and three gives birth to all things,'” Zhou explained. “KLIS started with three students and has since expanded into infinite possibilities.”

Today, the school has established a comprehensive K–12 American curriculum system, bringing together students from nearly 20 countries, and a diverse, professional team of educators. “The value of education is not determined by the size of its beginnings,” Zhou emphasized, “but by how faithfully it follows its founding mission to create the future.”

As a fully independent, nonprofit American international school, KLIS was founded with a clear mission—to serve the educational needs of foreign and overseas Chinese families living in Chongqing, while supporting the city’s efforts to build a more international business environment. To date, KLIS has provided quality education to over 800 students from the United States, Korea, Canada, Japan, Germany, Brazil, and many other countries and regions.

Building the Core of Future-Oriented Education

With the canvas laid out, how should it be painted? For Zhou, the heart of education is always people—especially in today’s world reshaped by artificial intelligence.

“Education is far more than the delivery of static knowledge; it’s about developing students’ abilities for rapid learning, interdisciplinary thinking, cross-cultural communication, and emotional well-being,” she said. KLIS follows the U.S. Common Core State Standards across all K–12 grades, adhering to a Student First approach that combines whole-child education with personalized learning pathways.

At KLIS, educational philosophy is put into daily practice. The school now offers over 20 AP courses and multiple interdisciplinary projects. Teachers customize learning paths based on individual differences, helping each student uncover their potential and pursue their aspirations.

Aside from Chinese courses, instruction at KLIS is entirely in English, emphasizing the cultivation of critical thinking, creativity, and problem-solving skills. “KLIS students should not only excel academically,” Zhou noted, “but also develop logical reasoning, mental wellness, global competence, and lifelong learning abilities—these are the true foundations for the future.”

Harvesting the Fruits of Forward-Thinking Education

“Over the past decade, there have certainly been challenges,” Zhou reflected, “but what remains constant is the emotion and fulfillment that come from witnessing our students’ growth and breakthroughs.”

In recent years, KLIS students have continued to excel, powerfully demonstrating the school’s educational philosophy in action. In the MAP testing, all grades scored above the global average in mathematics, and 9 out of 12 grades exceeded the English averages of native English-speaking countries. Students have also achieved outstanding results in international competitions, including the iGEM (International Genetically Engineered Machine Competition), the American Computer Science League, various mathematics contests, and the Asia Junior Golf Tour. Graduates have been admitted to top universities worldwide, such as University of California, Davis, University of Washington (Seattle), Purdue University, University of Toronto, McGill University, Yonsei University, Baylor University, and Imperial College London. In the 2025 Forbes China International School Rankings, KLIS ranked 34th nationwide for high schools and 29th for middle schools, both securing the top position in Chongqing.

“Standing at the new starting point of our 10th anniversary, the path ahead for KLIS is clearer than ever,” Zhou concluded. “As education evolves in the era of AI, KLIS will continue to uphold its three core values—personalized learning, cross-cultural understanding, and global competence—while exploring the frontiers of education in theory and practice. We look forward to walking hand in hand with parents, students, teachers, and partners to create an even more exciting decade ahead.”

Southern Cross University and NSBM Green University partner to deliver Australian degrees locally

LISMORE, Australia, Oct. 21, 2025 /PRNewswire/ — Southern Cross University (Australia) and NSBM Green University (Sri Lanka) will sign a groundbreaking partnership this Friday, 24 October, to deliver an offshore program that will allow Sri Lankan students to earn Australian degrees locally at NSBM – without needing to relocate to Australia.

Southern Cross University Australia and the National School of Business Management (NSBM) in Sri Lanka have partnered to offer an international business degree pathway delivered in Colombo.
Southern Cross University Australia and the National School of Business Management (NSBM) in Sri Lanka have partnered to offer an international business degree pathway delivered in Colombo.

This collaboration aims to expand access to globally recognised qualifications, enhance academic mobility, and deliver industry-aligned learning, while advancing joint research, enabling staff and student exchange, and strengthening ties between Australia and Sri Lanka.

“This initiative will provide highly cost-effective, world-class education to Sri Lankan students who can save a substantial amount on tuition and living expenses,” said Associate Dean (International & Engagement) Professor Darshana Sedera, who pioneered this program.

“This program will offer students a seamless pathway to transfer credits or continue their postgraduate studies at Southern Cross University in Australia,” said Professor Sedera. “At NSBM, we will launch the program with a Bachelor of Business in January 2026, with plans to later expand into information technology and health degrees. The collaboration will also involve Southern Cross University academics from Australia visiting NSBM regularly to deliver face-to-face teaching and engage in impactful research alongside NSBM staff and students.”

“We look forward to working closely with NSBM over the coming months and years, sharing knowledge, expertise, and best practices to drive mutual benefit and growth. Together, we will foster new opportunities for research, education, and community engagement, ultimately enriching the lives of students, staff and communities in both Australia and Sri Lanka,” said Professor Mike Ewing, Executive Dean of the Faculty of Business, Law and Arts at Southern Cross University.

The program will integrate Southern Cross’ innovative SCU Model and high academic standards with NSBM’s strong local infrastructure and faculty support, ensuring students receive the same quality education as their counterparts in Australia.

“We are excited to partner with Southern Cross University to offer their renowned, job-ready business programs at NSBM Green University. This collaboration provides our students with the opportunity to earn an Australian degree locally, equipping them with practical skills and industry-focused knowledge needed to succeed in a global economy and be workforce-ready,” said Professor. E.A. Weerasinghe, Vice-Chancellor at NSBM Green University.

This program ensures industry alignment, equipping graduates with globally relevant skills, and marks a significant step toward advancing accessible, high-quality education in Sri Lanka.

OH!SOME Launches Two Special Themed Collections Featuring Disney and Pixar’s Toy Story and Disney’s Zootopia


SINGAPORE – Media OutReach Newswire – 21 October 2025 – As Toy Story celebrates its 30th anniversary this year, OH!SOME launches an all-new collection inspired by the timeless charm of Disney and Pixar’s Toy Story. The special series debuts on October 15, celebrating the animated classic that has captured hearts across generations.

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Drawing inspiration from the iconic Pizza Planet scene first introduced in Toy Story (1995), OH!SOME brings Toy Story memories into everyday dining and cooking scenes. From bento boxes and tableware to sealed bags, insulation mats, fridge magnets and storage containers, the brand turns routine moments into playful, character-filled interactions.

“We hope to create a dialogue between iconic movie moments and everyday life,” said a spokesperson of OH!SOME. “This retro-styled line transforms beloved characters and scenes into functional art for daily use, taking fans back in time to relive treasured memories.”

The excitement doesn’t stop at the shelves. OH!SOME stores now feature themed check-in corners where fans can snap photos and share their favorite Toy Story memories. From October 16 to 30, fans can also join the challenge on Instagram and share personal memories in the designated post comments for a chance to win exclusive mystery IP gifts.

Launching alongside the Toy Story-themed collection, OH!SOME’s new Zootopia -themed series brings even more imaginative collectibles this season, including items designed for life on the go.

As a one-stop trendy retail brand under Blue Origin Group, OH!SOME has introduced several Disney-themed collections in 2025, catering to diverse lifestyle scenes. With over 150 stores across seven countries and regions, OH!SOME continues to expand its footprint across Asia, bringing more collaborations that merge lifestyle, creativity, and art.

Hashtag: #OH!SOME

The issuer is solely responsible for the content of this announcement.

VILEBREQUIN ARRIVES AT THE ST. REGIS BALI RESORT

A Celebration of Family Traditions and Elevated Seaside Living

BALI, Indonesia, Oct. 21, 2025 /PRNewswire/ — On the storied shores of Nusa Dua, The St. Regis Bali Resort proudly announces an exclusive collaboration with Vilebrequin, the iconic French luxury swimwear house from Saint-Tropez. Launching across select St. Regis resorts worldwide, the partnership introduces a limited-edition Family Capsule Collection alongside curated resort experiences designed to celebrate coastal living with refined sophistication.

Sunshine, family, and playful elegance at The St. Regis Bali Resort, where Vilebrequin brings a touch of Saint-Tropez charm to the Bali beach.
Sunshine, family, and playful elegance at The St. Regis Bali Resort, where Vilebrequin brings a touch of Saint-Tropez charm to the Bali beach.

A Capsule Collection Inspired by Family Traditions

At the heart of the collaboration lies the St. Regis x Vilebrequin Family Capsule Collection, a fusion of timeless elegance and Vilebrequin’s playful spirit.

The collection features exclusive swimwear for men, women, and children, complemented by pareos, plush towels, tote bags, and beach toys for little explorers. Each piece is adorned with vibrant illustrations inspired by cherished seaside moments, from building sandcastles under the sun to sailing on open waters, enhanced by a bespoke stripe pattern created exclusively for this collaboration.

Available from September 2025 through March 2026, the collection can be discovered at La Boutique within The St. Regis Bali Resort and select St. Regis resorts worldwide.

Immersive Experiences Beyond the Boutique

The collaboration transforms the resort into a stylish sanctuary where Vilebrequin’s playful designs meet St. Regis’s legendary elegance.

Along the golden sands of Nusa Dua, the beachfront Vista Bar adopts a vibrant new look, with co-branded umbrellas, cushions, and cabanas creating a chic seaside retreat.

Guests are invited to indulge in a bespoke dining journey at Vista Bar, featuring a specially curated menu of light, coastal-inspired seafood dishes paired with refreshing cocktails infused with a Vilebrequin twist.

Beyond dining, families can enjoy curated activities such as pony rides through lush gardens, sandcastle-building competitions, and interactive workshops at the resort’s Children’s Learning Center.

For ocean lovers, the experience continues with exclusive water-based adventures, from snorkeling in crystal-clear waters over thriving coral reefs to stand-up paddle yoga on custom-designed Vilebrequin boards and surfing lessons tailored to every skill level.

The Family Traditions Package

To complement the collaboration, The St. Regis Bali Resort introduces a Family Traditions Package designed to elevate family stays.

The package offers 20% savings on a second room for children up to 21 years old, complimentary dining for children under 12, and full access to the resort’s engaging Children’s Learning Center.

Completing the experience, the hallmark St. Regis Butler Service ensures every detail is flawlessly orchestrated, from unpacking the capsule wardrobe to arranging personalized family itineraries filled with memorable seaside moments.

A Shared Vision of Playful Sophistication

“At The St. Regis Bali Resort, each day unfolds in a palette of sun, sea, and shared moments,” said Héctor Busto, General Manager. “Our partnership with Vilebrequin brings Bali’s coastal charm to life, blending the resort’s family traditions with a spirited sense of style and sophistication.”

Availability

The St. Regis x Vilebrequin Family Capsule Collection and exclusive activations will launch in September 2025 and run through March 2026.

Guests can explore and purchase the collection at La Boutique within The St. Regis Bali Resort, with select pieces also available at St. Regis resorts worldwide, including Riviera Maya, Los Cabos, Bora Bora, Langkawi, Abu Dhabi, and more.

Discover more with our St. Regis x Vilebrequin Booklet or visit our website at www.stregisbali.com for additional information.

Orbbec Captures 72% of Korea’s Mobile Robot 3D Vision Market, New Report Shows

SHANGHAI, Oct. 21, 2025 /PRNewswire/ — Global market research firm Interact Analysis has released its 3D Vision for South Korean Mobile Robots report, revealing that Orbbec holds the No.1 position in Korea’s mobile robot 3D vision market with 72% market share in 2024.

According to Interact Analysis, Orbbec led Korea's commercial and industrial mobile robot 3D vision market with 72% share
According to Interact Analysis, Orbbec led Korea’s commercial and industrial mobile robot 3D vision market with 72% share

Based on surveys of over 60 robot manufacturers and distributors, the report finds Korea’s commercial and industrial mobile robot market reached KRW 300 billion (USD 220 million) in 2024. With the world’s highest robot density — 1,012 units per 10,000 employees — Korea remains a proving ground where robotics technologies must meet stringent performance standards before wider adoption.

The study highlights 3D cameras as key components enabling robots to navigate autonomously, detect obstacles, and ensure safe human-robot collaboration. In this field, Orbbec achieved 74% share in commercial mobile robots and 46% in industrial models, outperforming other suppliers including RealSense.

Analysts attribute Orbbec’s leadership to its comprehensive depth-sensing portfolio, robust supply chain, and collaboration with robot makers across Asia, North America, and Korea. Many of Korea’s leading logistics, hospitality, and manufacturing robots — operating in warehouses, restaurants, and factories — now use Orbbec’s 3D cameras as their primary vision systems.

Korea’s robotics sector plays a pivotal role in global automation, spanning electronics, automotive, and logistics. The growing integration between Korean robotics expertise and global 3D vision technologies reflects the region’s evolving ecosystem, where complementary strengths drive innovation.

“Achieving market leadership in Korea — known for demanding quality standards and technological sophistication — validates our commitment to delivering world-class depth-perception solutions,” said Felix Zheng, Managing Director, APAC Region at Orbbec. “We view Korea as a long-term strategic market and will continue investing in partnerships and technical support to advance robotics innovation with Korean partners.”

About Orbbec
Founded in 2013, Orbbec (SHA: 688322) is a leading provider of robotics and AI vision technologies, offering advanced 3D sensing solutions based on structured light, stereo vision, ToF, and LiDAR. An official ecosystem partner of NVIDIA, Microsoft, and AMD, Orbbec combines deep R&D expertise with proven OEM/ODM capabilities, serving over 3,000 clients worldwide across manufacturing, logistics, and service robotics — including extensive deployments in Korea.

Trinasolar and Mestron Energy Ink MOU to Strengthen Malaysia’s National Energy Transition Roadmap Goals

Partnership to supply 50MW of Vertex N-type modules for renewable projects across Malaysia.

SINGAPORE, Oct. 21, 2025 /PRNewswire/ — Trinasolar, a global leader in smart photovoltaic (PV) and energy storage solutions, has signed a memorandum of understanding (MoU) with Mestron Energy, a specialist in renewable power generation in Malaysia, to deploy solar energy in Malaysia. As per the terms of the agreement, Trinasolar will supply 50MW of Vertex N solar modules, supporting Mestron’s renewable energy projects and Malaysia’s broader sustainability ambitions.

This collaboration demonstrates the synergy of two industry leaders: Trinasolar, bringing world-class solar technology and global expertise, and Mestron Energy, leveraging its strong local footprint and experience in renewable energy deployment.

“We’re pleased to partner with Mestron Energy to deliver advanced, cost-effective solar solutions that support Malaysia’s clean-energy ambitions,” said Ku Jun Heong, Vice President of Trinasolar‘s Asia Pacific, Middle East and Africa region. “Our Vertex N modules are designed to maximize energy yield and help lower levelized cost of energy.”

“Partnering with Trinasolar presents an excellent opportunity to support Malaysia’s and ASEAN’s renewable energy development. We believe that solar installations will significantly reduce greenhouse gas emissions and help create a sustainable future.” Por Teong Eng, Managing Director of Mestron Energy, said.

Mestron Energy, a publicly-listed company within the Mestron Holdings Berhad group on the Malaysian Stock Exchange, has comprehensive expertise in managing renewable energy projects—including solar and energy management solutions. By integrating Trinasolar’s cutting-edge technologies, Mestron Energy is well-positioned to scale its renewable portfolio and drive Malaysia’s transition toward a low-carbon economy.

This partnership underscores the growing demand for corporate renewable energy solutions in Malaysia, while also highlighting ASEAN’s potential as a hub for clean energy development.

The MoU was exchanged by Por Teong Eng, Managing Director of Mestron Energy (Left), and KU Jun Heong, Trinasolar’s Vice President of Asia Pacific, Middle East and Africa Region (Right)
The MoU was exchanged by Por Teong Eng, Managing Director of Mestron Energy (Left), and KU Jun Heong, Trinasolar’s Vice President of Asia Pacific, Middle East and Africa Region (Right)

About Trinasolar 

Founded in 1997, Trinasolar Co., Ltd., specializes in PV products, system solutions, and smart energy. Our PV products encompass research and development, production, and sales of PV modules. Our PV systems include power stations and related products. In smart energy, we focus on PV power generation, operation and maintenance, energy storage solutions, smart microgrids, and the development and sales of multi-energy systems. We are dedicated to leading the way in smart solar energy solutions and supporting the transition to new power systems for a net-zero future.

Globalization is a key strategy for Trinasolar. From its inception, the company has been building its global presence. Trinasolar was founded in Changzhou, Jiangsu Province, China, where our global headquarters remain. In 2022, we established our international headquarters in Shanghai and have been actively strengthening our global teams. As a global leader in solar and smart energy storage solutions, Trinasolar has delivered numerous integrated solar and energy storage projects worldwide. Testament to its bankability and reliability, Trina Storage retains Top Rank in BNEF’s 2024 Global Storage Providers and Integrators Bankability

About Mestron Energy

Mestron Energy, part of Mestron Holdings Berhad, is a Malaysia-based renewable energy developer with expertise across solar, and energy management solutions. The company is committed to supporting Malaysia’s clean energy transition and contributing to sustainable growth in the ASEAN region.