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First Phosphate Obtains High Purity 40.2% Apatite Concentrate in Metallurgical Testwork Based on Lac à L’Orignal Property in Quebec, Canada

Saguenay, Quebec – Newsfile Corp. – 20 March 2023 – First Phosphate Corp. (CSE: PHOS) (FSE: KD0) (“First Phosphate” or the “Company“) is pleased to announce that it has obtained Metallurgical Testwork results on mineralization sourced from its Lac à l’Orignal Property in the region of Saguenay-Lac-St-Jean, Quebec, Canada. The testwork was completed by an independent laboratory, SGS Canada Inc., Quebec City, Quebec, and dated March 13, 2023. The full report is available at: https://firstphosphate.com/projects/assets.

The results from the batch and locked cycle tests were used to prepare an overall mass balance for the proposed flowsheet. The overall mass balance showed that the flowsheet could recover 91.4% of the apatite to a concentrate containing 40.2% P2O5.

Preliminary upgrading testwork on the ilmenite and magnetite streams achieved an ilmenite concentrate grading 39.3% TiO2 and a magnetite concentrate grading 69.0% Fe (99.2% Fe2O3). Further testwork is recommended to optimize the ilmenite circuit.

“We are pleased with the results of our high purity apatite recovery which has the potential to allow us to create a large amount of purified phosphoric acid for the production of LFP batteries,” says First Phosphate President, Peter Kent. “Our secondary recovery of ilmenite is equally important in that its upgrading may allow us to create the iron sulphate required as another important ingredient in the production of LFP batteries. The magnetite remains a potential tertiary recovery of value. We are now able to proceed towards a beneficiation pilot plant ahead of schedule.”

The metallurgical testwork program was undertaken on a composite of 75 fluoroapatite half drill cores from the Lac à l’Orignal Deposit with the objective of recovering and upgrading the apatite (removing silicates, ilmenite, magnetite, etc.) to produce high grade concentrate feed for phosphoric acid production to be used in the production of LFP cathode active material. The composite sample had a head grade of 5.55% P2O5.

Qualified Person

The scientific and technical disclosure for First Phosphate included in this news release have been reviewed and approved by D. Grant Feasby, P.Eng. of P&E Mining Consultants Inc. Mr. Feasby is a metallurgist and a Qualified Person under National Instrument 43-101 Standards of Disclosure of Mineral Projects (“NI 43-101”).

About First Phosphate Corp.

First Phosphate is a mineral development company fully dedicated to extracting and purifying phosphate for the production of cathode active material for the Lithium Iron Phosphate (“LFP”) battery industry. First Phosphate is committed to producing at high purity level, at full ESG standard and with low anticipated carbon footprint. First Phosphate plans to vertically integrate from mine source directly into the supply chains of major North American LFP battery producers that require battery grade LFP cathode active material emanating from a consistent and secure supply source. First Phosphate holds over 1,500 sq. km of total land claims in the Saguenay-Lac-St-Jean Region of Quebec, Canada that it is actively developing. First Phosphate properties consist of rare anorthosite igneous phosphate rock that generally yields high purity phosphate concentrate devoid of high levels of deleterious elements.

For additional information, please contact:

Peter Kent, President
peter@firstphosphate.com
Tel: +1 (647) 707-1943

Investor Relations: investor@firstphosphate.com
Media Relations: media@firstphosphate.com
Website: www.FirstPhosphate.com

Follow First Phosphate:
Twitter: https://twitter.com/FirstPhosphate
LinkedIn: https://www.linkedin.com/company/first-phosphate/

Forward-Looking Information and Cautionary Statements

Certain information in this news release constitutes forward-looking statements under applicable securities laws. Any statements that are contained in this news release that are not statements of historical fact may be deemed to be forward-looking statements. Forward-looking statements are often identified by terms such as “may”, “should”, “anticipate”, “expect”, “potential”, “believe”, “intend” or the negative of these terms and similar expressions. Forward-looking statements in this news release include statements relating to: the Company’s commitment to producing high purity phosphate materials at full ESG standard under a low carbon footprint; the Company’s plans to integrate directly into the functions of certain major North American LFP Battery producers; the Company’s proposed development of its land claims in the region of Saguenay-Lac-St-Jean, Quebec; the availability of the metallurgical testwork report on the Company’s website; the estimated recovery rates contained in the report and the potential of such recovery rates in allowing the Company to create a large amount of purified phosphoric acid and iron sulphate, both used in the production of LFP batteries; the potential recovery of magnetite as a potential tertiary recovery of value; and the Company’s plans, if any, to expand or carryout its metallurgical programs.

Forward-looking information in this press release are based on certain assumptions and expected future events, namely: the Company’s ability to producing high purity phosphate materials at full ESG standard under a low carbon footprint; the Company’s ability to integrate directly into the functions of certain major North American LFP Battery producers; the Company’s ability to develop its land claims in the region of Saguenay-Lac-St-Jean, Quebec; the ability of the Company to provide the metallurgical testwork report on the Company’s website; the Company’s ability to meet and exceed the stated recovery rates to allow the Company to create a large amount of purified phosphoric acid and iron sulphate; the Company’s ability to carry out its recovery of magnetite as a tertiary recovery of value; and the Company’s ability to accomplish its plans, if any, with respect to its metallurgical programs or the expansion thereof.

These statements involve known and unknown risks, uncertainties and other factors, which may cause actual results, performance or achievements to differ materially from those expressed or implied by such statements, including but not limited to: the Company’s inability to produce high purity phosphate materials at full ESG standard under a low carbon footprint; the Company’s inability to integrate directly into the functions of certain major North American LFP Battery producers; the Company’s inability to develop its land claims in the region of Saguenay-Lac-St-Jean, Quebec; the inability of the Company to provide the metallurgical testwork report on the Company’s website; the Company’s inability to meet and exceed the stated recovery rates to allow the Company to create a large amount of purified phosphoric acid and iron sulphate; the Company’s inability to carry out its recovery of magnetite as a tertiary recovery of value; and the Company’s inability to accomplish its plans, if any, with respect to its metallurgical programs or the expansion thereof.

Readers are cautioned that the foregoing list is not exhaustive. Readers are further cautioned not to place undue reliance on forward-looking statements, as there can be no assurance that the plans, intentions or expectations upon which they are placed will occur. Such information, although considered reasonable by management at the time of preparation, may prove to be incorrect and actual results may differ materially from those anticipated.

Forward-looking statements contained in this press release are expressly qualified by this cautionary statement and reflect the Company’s expectations as of the date hereof and are subject to change thereafter. The Company undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, estimates or opinions, future events or results or otherwise or to explain any material difference between subsequent actual events and such forward-looking information, except as required by applicable law.

The issuer is solely responsible for the content of this announcement.

Fosun’s Businesses Show an Upward Trend, Nomura Reiterates its “Overweight” Rating

HONG KONG SAR – Media OutReach – 20 March 2023 – On 19 March 2023, Nomura Orient International Securities (“Nomura”) published a research report, stating that with the strategy of focusing on core businesses, Fosun International Limited’s (“Fosun International” or the “Company”) (stock code: 00656.HK) operations have continued to improve. In the future, Fosun will focus on core businesses, innovation, and globalization. Nomura believes that with strong strategic determination, Fosun’s business recovery is just around the corner, thus maintaining “overweight” rating on Fosun International, with a target price of HK$9.20.

Nomura pointed out that Fosun recently announced it has formally signed an agreement with Shagang Group on the transfer of 60% of the equity of Nanjing Nangang Iron & Steel United, and the overall transaction plan is progressing smoothly. Nomura believes that focusing on its core businesses and streamlining the organization is still the main strategic direction of Fosun International. Nomura also believes that Fosun’s accelerated disposal of non-core businesses, consolidated capital buffer, active approach to adjust business structure, and focus on core businesses with high growth potential in the household consumption sector will enable the Company to achieve more valuable growth. At the same time, as Fosun continues to implement the strategy, Nomura believes that concerns regarding the Company’s leverage ratio and liquidity will subside, and Fosun’s fundamental operations are on an upward trend.

In addition, Nomura expressed optimism about Fosun’s globalization strategy, and believes that Fosun International has formed solid globalization capability, which allows the Company to leverage its global business presence to gather resources around the world for customers worldwide. In terms of innovation, Fosun has always maintained a high investment in R&D, building a global innovation system led by product innovation, digital intelligence innovation, and management innovation, and leading the upgrade of family happiness with innovation.

On 17 and 18 March, Guo Guangchang, Chairman of Fosun International, attended the 23rd Annual Conference of Yabuli China Entrepreneurs Forum 2023, and the 6th Shanghai Forum Themed Zhejiang Entrepreneurs in the World & the 11th Member Representative Conference of ZCCS (Zhejiang Chamber of Commerce in Shanghai) hosted by the ZCCS, respectively. Guo Guangchang pointed out in his speech that for the future development, Fosun will first focus on innovation and R&D investment, especially in biopharmaceuticals. Secondly, Fosun will step up its efforts to improve global innovation capabilities and operational capabilities. Fosun has full confidence in its overall development goals for this year.

Guo Guangchang said that since the beginning of this year, he has truly felt the rapid recovery of consumption, offline consumption in particular. In fact, Fosun’s various businesses demonstrated optimistic performance in both domestic and overseas markets: Yuyuan Garden Lantern Festival became an Internet sensation this year and attracted more than 4 million visitors. The recovery of the tourism industry is even more evident, the occupancy rate of Atlantis Sanya under Fosun Tourism Group (FTG) has exceeded 90% since mid-January and has exceeded 99% during Chinese New Year. In terms of overseas markets, Club Med posted the highest single-month business volume in its history of more than 70 years since its establishment.

The robust recovery and steady development of various businesses conveyed a positive signal of Fosun’s development momentum. Fosun will continue to focus on innovation, adhere to global operations, and continue to achieve steady development this year.

Hashtag: #Fosun

The issuer is solely responsible for the content of this announcement.

First, Largest Youth-Led Economic Forum Takes Place in Southeast Asia

First Youth-Led Economic Forum in Southeast Asia Building Cooperation for a Sustainable Future
A group photo with all the delegates and VIP guests

The ASEAN Youth Organization has organized the first and largest youth economic forum, called the ASEAN Youth Economic Forum (AYEF) 2023 with the theme of “Building A More Inclusive Youth Participation in ASEAN-Japan Friendship” to celebrate the commemoration of the 50th ASEAN-Japan Relationship Anniversary.

Thailand Dissolves Parliament Ahead Of May Election

Thailand Dissolves Parliament Ahead Of May Election
Thai PM Prayuth Chan-ocha's main opponent will be his predecessor Thaksin Shinawatra's daughter Paetongtarn ( Photo : REUTERS )

King Maha Vajiralongkorn of Thailand has sanctioned the dissolution of the country’s House of Representatives, effectively launching the campaign season ahead of the forthcoming May elections.

Top 10 Largest Spiders in the World- The Biggest is in Laos!

Close-up female of Spider Tarantula in threatening position. ( Photo: iStock).
Close-up female of Spider Tarantula in threatening position. ( Photo: iStock).

Decorations of realistic spiders or webs hanging from the ceiling make the house feel spookier on Halloween, but the spiders on this list will surprise you with their giant body sizes and unique characteristics. Hopefully, they don’t creep up behind you!

Hong Kong Baptist University-led research unveils cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19

HONG KONG SAR – Media OutReach – 20 March 2023 – A study led by scientists from Hong Kong Baptist University (HKBU) has identified a protease called MT1-MMP that is a major host factor behind the infectivity of the SARS-CoV-2 virus in the human body, which leads to the infection of COVID-19 and multi-organ failure. By applying a humanised antibody called 3A2 that can inhibit the activity of MT1-MMP, the viral load of infected mice was reduced by almost 90%. The research team also demonstrated that the protease is a potential therapeutic target for COVID-19.

Dr Xavier Wong Hoi-leong, Assistant Professor, and Dr Guo Xuanming, researcher of the Teaching and Research Division of the School of Chinese Medicine, introduce the research findings on the cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19.
Dr Xavier Wong Hoi-leong, Assistant Professor, and Dr Guo Xuanming, researcher of the Teaching and Research Division of the School of Chinese Medicine, introduce the research findings on the cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19.

The research findings have been published in the internationally renowned scientific journal Nature Communications.

ACE2 as a receptor for SARS-CoV-2 cell entry

Vaccination can protect people against COVID-19 and its potential complications, but it is not always effective in individuals with weak immune systems, or against some COVID-19 variants of concern. Thus, the development of a more effective treatment for COVID-19 remains a huge challenge in the post-vaccine era. Understanding the cell entry mechanism of SARS-CoV-2 is vital to curb the spread of the virus, and it will also aid the search for new COVID-19 treatments.

SARS-CoV-2 requires angiotensin-converting enzyme 2 (ACE2), a protein found on the membrane of human cells, as its receptor for cellular entry. Despite the lungs being the major organ affected by SARS-CoV-2 infection, only a small proportion of lung cells express ACE2.

Previous studies found that the infection of organs with low levels of ACE2 expression by SARS-CoV-2 is made possible by a soluble form of ACE2. The soluble ACE2 binds with SARS-CoV-2, carries the virus to cells with low levels of ACE2 expression, and facilitates its entry into the cells.

MT1-MMP mediates cell entry of SARS-CoV-2

A research team led by Dr Xavier Wong Hoi-leong, Assistant Professor of the Teaching and Research Division of the School of Chinese Medicine at HKBU, in collaboration with Dr Yuan Shuofeng, Assistant Professor of the Department of Microbiology at The University of Hong Kong, further studied how the physiological regulation of soluble ACE2 shedding contributes to the aetiology of COVID-19.

The team found that SARS-CoV-2 infection leads to the increased activation of MT1-MMP, a protease crucial for many physiological processes. MT1-MMP mediates the release of soluble ACE2 from ACE2-expressing cells. This soluble ACE2 in turn binds to the spike proteins of SARS-CoV-2 and carries it to the uninfected cells with low levels of ACE2 expression.

Notably, the team demonstrated that the introduction of human-soluble ACE2 enables SARS-CoV-2 to infect the lungs of a laboratory mouse strain (C57BL/6 mice) that is naturally insusceptible to SARS-CoV-2 infection due to the incompatibility of its mouse ACE2 and the viral spike proteins. The findings unveil the mechanism by which the virus hijacks host enzymes to enhance its infectivity, triggering multi-organ infections.

Antibody 3A2 blocks MT1-MMP activity

To study MT1-MMP’s functions and how it affects viral infection, the researchers used human cells to create organoids, a 3D tissue structure grown in vitro to resemble and model different organs in the laboratory.

They discovered that blocking MT1-MMP activity with the monoclonal antibody 3A2 effectively depleted soluble ACE2 levels and reduced the degree of infection of SARS-CoV-2 in human lung, heart and liver organoids by 60-80%. Consistent results were obtained using the original strain of SARS-CoV-2, as well as variants of concern, such as Delta and Omicron. The results demonstrate that MT1-MMP is a major host factor that mediates the cell entry of SARS-CoV-2, and that it is also a potential therapeutic target for COVID-19 drugs.

The researchers further tested the effects of applying 3A2 in a mouse COVID-19 model. A group of 11 mice were treated with either 3A2 or vehicle controls. Older mice were used in the experiment as old age is a major risk factor for severe symptoms and mortality for COVID-19. The results show that 3A2 reduced the viral load of SARS-CoV-2 by almost 90% and dramatically alleviated lung tissue damage resulting from infection.

MT1-MMP as a therapeutic target

Dr Wong said: “Two major challenges when it comes to developing COVID-19 drugs are how to enhance treatment results for patients with weakened immune systems, and how to maintain the drugs’ effectiveness across different viral strains. 3A2 has good potential to become an effective drug for curing COVID-19 because it antagonises the activity of MT1-MMP, instead of boosting the immunity of patients or acting directly on the virus.

“Our previous studies have demonstrated that 3A2 also offers protection against obesity and diabetes, two major risk factors for severe symptoms and mortality for COVID-19. Therefore, 3A2 could be particularly suitable for high-risk groups, including older adults and people with metabolic disorders. It could also be effective against emerging coronaviruses in the future, because ACE2 is a doorway for many such viruses with similar cell entry mechanisms. Further research and experiments on 3A2 are required before it can be applied in humans.”

Hashtag: #HKBU

The issuer is solely responsible for the content of this announcement.

Burning, Logging Rife in Phou Khao Khouay National Park

Logging, burning rife in Phou Khao Khouay National Park
Logging, burning rife in Phou Khao Khouay National Park.

Tourists visiting the Phou Khao Khouay National Park in Laos have reported witnessing widespread logging and agricultural burning, practices that are damaging the park’s delicate ecosystem.

China’s High-end Manufacturing Products from Electromechanical Field Show up in Singapore

BEIJING, CHINA – Media OutReach – 20 March 2023 – From March 22 to 24, China’s Machinery & Electronics Show in Singapore (CMESS 2023), together with the First International Industrial Cooperation Conference jointly hosted by China Chamber of Commerce for Import and Export of Machinery and Electronic Products (CCCME) and Singapore Chinese Chamber of Commerce & Industry (SCCCI) will be launched in Hall D &E, B2, Marina Bay Sands in Singapore.

A number of central state-owned enterprises and leading private sectors from China are coming to Singapore with their high-end manufacturing products from electromechanical industry this time, so as to open new opportunities for win-win cooperation with international enterprises from the globe.

  1. About CMESS 2023
    1. Exhibition area: 8000m²
    2. Exhibitors: 133 Branding Companies
    3. Audience: 5000 to 6000 persons
    4. Media: 50
  2. Exhibits
    1. Infrastructure: comprehensive solutions of infrastructure.
    2. Home appliances and Innovative products: home appliances and consumer electronics industry, Internet of things, video and audio entertainment, cooking and delicacy, intelligent security, health and other smart home scenes, from “smart home” to “smart community” to “smart city” in the full scene smart life application scheme in the future.
    3. Electric power & New energy: PV and other new energy power generation technology and equipment, power transmission and distribution and control equipment, intelligent technology and application of electric power, etc.
    4. Industrial machinery: machine tools, agricultural and food machinery, etc.
  3. Spotlights
    1. High-profile exhibition combined with series of forums topic on international industrial cooperation, accompanied with showcases of fruitful technical achievement.
    2. Industrial leaders combined with SMEs, jointly shape the international brand image featuring with “Intelligent Manufacturing in China”.
    3. Supported by China’s provincial government from Beijing, Shandong, Guizhou, Fujian, Henan and other official sectors, industrial cluster effect can be enlarged.
  1. The list of exhibitors from China(Partially Only)
    1. China State Construction Engineering Corporation (CSCEC)
    2. China Communications Construction Company Limited
    3. China National Chemical Engineering Group Corporation Limited
    4. Power Construction Corporation Of China(POWER CHINA)
    5. Haier
    6. Ecovacs Robotics Co., Ltd.
    7. JA SOLAR Technology Co., Ltd.
    8. LONGi Green Energy Technology Co., Ltd. (LONGi)
    9. Zhejiang CHINT Electrics Co., Ltd.
    10. Gacia Electrical Appliance Co., Ltd.
    11. Guangzhou Industrial Investment Holdings Group
    12. Lingdu (Guangdong) Intelligent Technology Development Co., Ltd.
  1. Registration for professional visitors and buyers

https://www.gevme.com/cmes2023-register

  1. Contacts of CCCME:

Ms. Zhu Xiaomin, Ms. Liu Zhuohan
Email:cmess@cccme.org.cn

Hashtag: #CMESS2023

The issuer is solely responsible for the content of this announcement.