• Bitmine’s Board of Directors declares initial cash dividends on the Company’s 9.50% Series A Perpetual Preferred Stock
• Series A Preferred Stock approved for listing on the New York Stock Exchange under the symbol “BMNP” with trading expected to commence on Tuesday, June 16, 2026

NORWALK, Conn., June 13, 2026 /PRNewswire/ — (NYSE: BMNR) Bitmine Immersion Technologies, Inc. (“Bitmine” or the “Company“) announced today that its Board of Directors has declared the initial cash dividends on the Company’s 9.50% Series A Perpetual Preferred Stock (CUSIP: 09175D 200) (the “Series A Preferred Stock“).

The initial dividend, which represents accumulated regular dividends from the initial issue date of June 10, 2026, will be payable in cash in accordance with the terms of the Certificate of Designations governing the Series A Preferred Stock. The initial dividend of $0.316667 per share will be paid on June 22, 2026 to holders of record of the Series A Preferred Stock as of the close of business on June 12, 2026.

The Company further announced that the Board of Directors also declared the second weekly cash dividend of $0.105556 per share on the Series A Preferred Stock, which will be paid on June 26, 2026 to holders of record of the Series A Preferred Stock as of the close of business on June 16, 2026.

The Company also announced that the Series A Preferred Stock has been approved for listing on the New York Stock Exchange and will begin trading on Tuesday, June 16, 2026 under the ticker symbol “BMNP”. Equiniti Trust Company, LLC serves as the transfer agent, registrar and paying agent for the Series A Preferred Stock.

About Bitmine
Bitmine (NYSE: BMNR) is a Bitcoin miner with operations in the US. The company is deploying its excess capital to be the leading Ethereum Treasury company in the world, implementing an innovative digital asset strategy for institutional investors and public market participants. Guided by its philosophy of “the alchemy of 5%,” the Company is committed to ETH as its primary treasury reserve asset, leveraging native protocol-level activities including staking and decentralized finance mechanisms. The Company launched MAVAN (Made-in America VAlidator Network), a dedicated staking infrastructure for Bitmine assets, in 2026.

For additional details, follow on X:
https://x.com/bitmnr
https://x.com/fundstrat

Forward-Looking Statements

This press release contains statements that constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. The statements in this press release that are not purely historical are forward-looking statements which involve risks and uncertainties. These forward-looking statements can be identified by terms such as “expects,” “projects,” “projected,” “intends,” “believes,” “anticipates,” “estimates,” and similar expressions. This document specifically contains forward-looking statements regarding the Company’s dividend payments on the Series A Preferred Stock, the listing and commencement of trading of the Series A Preferred Stock on the New York Stock Exchange, and the Company’s digital asset accumulation strategy and staking operations. In evaluating these forward-looking statements, you should consider various factors, including: Bitmine’s ability to finance its current business, Ethereum treasury operations, and proposed future business; market conditions affecting the trading price of the Company’s common stock and Series A Preferred Stock; regulatory developments affecting digital assets, including the ultimate enactment and implementation of pending legislation and SEC initiatives; the volatility and unpredictability of digital asset prices; the performance, reliability, and security of the Company’s staking operations; and the future value of Bitcoin and Ethereum. Actual future performance outcomes and results may differ materially from those expressed in forward-looking statements. Forward-looking statements are subject to numerous conditions, many of which are beyond Bitmine’s control, including those set forth in the Risk Factors section of Bitmine’s Form 10-K filed with the SEC on November 21, 2025, as well as all other SEC filings, as amended or updated from time to time. Copies of Bitmine’s filings with the SEC are available on the SEC’s website at www.sec.gov. Bitmine undertakes no obligation to update these statements for revisions or changes after the date of this release, except as required by law.

LOS ANGELES, June 13, 2026 /PRNewswire/ — Southern California homeowners are facing longer hot seasons, rising utility costs, and evolving lifestyle needs. As a result, demand for flexible, energy-efficient cooling solutions continues to rise across the region with no signs of slowing down.

DELLA, a leading provider of ductless mini split systems, is helping homeowners meet these changing demands with smart, room-specific cooling solutions. As modern households seek greater comfort, convenience, and energy efficiency, ductless systems offer an effective alternative to relying solely on traditional whole-home climate control.

The Shift Toward Smarter Home Climate Control

This pronounced shift reflects a growing trend reshaping home comfort. Today’s homeowners are no longer focused only on keeping a house cool. Increasingly, they want personalized comfort that adapts to how different rooms are being used throughout the day.

Modern smart homes no longer function as a single environment with a uniform temperature. Climate fluctuates naturally throughout the day based on a variety of factors, and each room serves a completely different purpose.

Yet many traditional HVAC systems continue to cool the entire household as though every room and every person require the same temperature.

To remedy this, homeowners across Southern California are exploring room-by-room climate control solutions that provide greater flexibility and efficiency.

Why Traditional Central AC Often Feels Inconsistent

Most central air systems were designed around a simple old-fashioned idea: one thermostat controls the entire home. But modern living has changed dramatically.

Different rooms heat up differently based on sunlight, layout, occupancy, electronics, cooking activity, ceiling height, and even the time of day. The result is a home that constantly feels slightly off balance.

Common frustrations include:

• Bedrooms that stay warm long after sunset
• Overcooled living rooms during the day
• Upstairs areas that never feel comfortable
• Constant thermostat adjustments
• Rising summer energy bills without better comfort

The issue isn’t always that a system is failing—it’s that the system was designed for an older idea of how homes function.

Today, homeowners are searching for energy efficient cooling systems that support room-by-room living rather than treating the home as a single environment.

Because real comfort is not just about what the thermostat says.

It’s about how a home actually feels.

This is why DELLA provides energy efficient cooling systems that adapt to how people actually live instead of forcing one fixed temperature across the entire home.

How DELLA Mini Split Systems Address Changing Homeowner Needs

DELLA mini split systems were designed around the growing demand for personalized comfort and more efficient cooling.

Instead of pushing air through extensive ductwork from a single central source, mini split systems deliver targeted comfort directly into individual rooms. Each indoor unit operates independently, allowing temperatures to adjust naturally based on how each space is being used.

That flexibility changes the entire home comfort experience.

Rather than overcooling one area to compensate for another, homeowners can create balanced comfort throughout the home in a way that feels quieter, more efficient, and better aligned with daily routines.

This is one reason ductless mini splits and smart climate systems continue gaining popularity throughout Southern California, particularly during extended periods of summer heat.

The goal is no longer simply more air conditioning.

It is smarter comfort that works in the background while adapting naturally to everyday life.

Key advantages include:

• Room-by-room temperature control
• Faster cooling response times
• Lower energy waste compared to traditional ducted systems
• Quiet air conditioner performance for bedrooms and living spaces
• Flexible installation without major renovation work
• More balanced airflow throughout the home

For many homeowners, the biggest difference is how natural the comfort feels.

The best climate systems don’t constantly remind you they’re running. They quietly support the way people actually live.

Homes Aren’t One Temperature Anymore

A bedroom may require cooler nighttime temperatures for improved sleep quality.

A home office may need consistent daytime cooling during work hours.

A kitchen naturally generates heat during cooking.

Living rooms may fluctuate based on gatherings, sunlight exposure, entertainment equipment, and daily activity.

Traditional HVAC systems often struggle to respond to these changing conditions because they treat the entire house as a single cooling zone.

That is where zoned cooling for homes becomes a significant advantage.

Mini split systems allow homeowners to cool spaces individually rather than forcing a single setting throughout the home. The result is more precise comfort, improved efficiency, and a living environment that better reflects how people use their homes today.

The DELLA Mini Split Collection

DELLA offers a complete collection of ductless cooling systems designed to adapt to virtually any lifestyle, home layout, or comfort preference. Three of the company’s most popular models — the Serena, Optima, and Vario Series — each deliver a different approach to modern comfort while emphasizing efficiency, quiet performance, and flexible everyday living.

The Serena Series focuses on balanced whole-home comfort with smooth, quiet operation and up to 22 SEER2 efficiency, making it an ideal choice for consistent daily use.

The Optima Series is designed for multi-zone precision, allowing homeowners to independently control temperatures in different rooms for greater comfort and improved efficiency throughout the home.

Meanwhile, the Vario Series offers a practical and budget-conscious solution for targeted cooling in bedrooms, home offices, garage conversions, apartments, and ADUs.

Together, these systems reflect DELLA’s broader approach to smart, adaptable comfort built around the way modern homeowners actually live.

Quiet Comfort Is the New Luxury

One of the biggest changes happening in modern home comfort is that homeowners are becoming more sensitive to how cooling feels — not just whether cold air exists.

Older systems often rely on aggressive airflow, loud cycling, or constant thermostat adjustments that make the cooling experience feel noticeable and disruptive.

But modern comfort trends are shifting toward quieter, more balanced environments.

People want bedrooms that stay cool without loud airflow at night.

They want living spaces that feel evenly comfortable without cold blasts of air hitting one side of the room.

They want systems that operate quietly in the background while daily life continues naturally.

This is why mini split systems are increasingly viewed as both a lifestyle upgrade and an efficiency upgrade.

DELLA’s technology supports a softer, more adaptive approach to cooling that aligns with how modern homes are actually being used.

Energy Efficiency That Supports Everyday Living

Energy savings remain one of the strongest practical advantages of mini split systems.

Unlike traditional HVAC systems that repeatedly cycle on and off, inverter technology continuously adjusts output to maintain stable temperatures more efficiently.

This leads to:

• Lower monthly utility costs
• Reduced energy waste
• More stable indoor temperatures
• Less system strain over time
• Improved long-term efficiency performance

For homeowners dealing with Southern California summers, those efficiency gains often become noticeable quickly, especially during extended heat waves when cooling systems run for longer periods throughout the day.

Southern California Home Comfort

Real comfort is about creating spaces that feel balanced, natural, and comfortable exactly where and when you need them most. DELLA provides homeowners, especially those in areas with hot climates like Southern California, with all the right options to save money, conserve energy, and stay truly comfortable.

New capabilities transform rigid company and team operations, complex payment setups, and developer workflows into seamless, natural-language actions—drastically shortening the bridge between product launch and revenue.

SAN FRANCISCO, June 13, 2026 /PRNewswire/ — Subotiz, the AI-driven subscription commerce and payment infrastructure platform tailored for AI, SaaS, and digital entertainment enterprises, recently announced the launch of its pioneering AI Agent Suite and Subotiz MCP Server. This unified release introduces a powerful new layer of capability, enabling AI companies and developers to architect, manage, and scale global subscription commerce entirely through natural language.

The launch addresses a critical bottleneck in the fast-moving digital economy. While the generative AI boom has made building a digital product faster and cheaper than ever, the commercialization phase remains bogged down by legacy complexity. Transitioning from a viable product to a revenue-generating business still requires navigating fractured workflows: configuring complex subscription tiers, aligning localized payment gateways, auditing data anomalies, and debugging developer APIs.

Traditionally, these tasks forced lean teams to context-switch across disconnected dashboards, dense API references, and internal support tickets. Subotiz is collapsing these silos into a single, cohesive, AI-assisted operating experience. While the AI Agent Suite automates complex operational workflows inside the Subotiz platform, the Subotiz MCP Server allows external AI tools to hook directly into Subotiz’s subscription, billing, and developer pipelines.

“AI shouldn’t just answer user prompts; it should execute heavy-lifting operational workflows,” said Ryan Yang, Solution Director at Subotiz. “With our AI Agent Suite and MCP Server, we are shifting subscription commerce from manual configuration to intent-driven execution. Companies simply describe the business outcome they want, and Subotiz translates that intent into production-ready operational and technical reality.”

The AI Agent Suite: Five Specialized Agents, One Conversational Dashboard

Rather than relying on a generic chatbot, Subotiz has engineered five purpose-built agents mapped to high-frequency subscription commerce friction points:

• The Collect Agent (Frictionless Intake): Streamlines the initial onboarding grind. By ingestion of unstructured business context during registration, it eliminates the need to study compliance documentation, automatically recommending tailored payment methods, optimal pricing structures, and localized operational setups.

• The Onboard Agent (Accelerated Time-to-Value): Cross-references merchant profiles with Subotiz’s proprietary business strategy library to map out a customized, step-by-step launch path, auto-filling technical configuration fields to accelerate time-to-market.

• The Merchant Agent (Conversational Operations): Acts as a 24/7 co-pilot for daily business tweaks. Through multi-turn natural language conversations that retain context, users can spin up new subscription products, modify pricing plans, or update business settings without digging through menus.

• The Data Agent (Proactive Business Diagnosis): Moves beyond passive, static reporting. The agent actively detects revenue anomalies, analyzes root causes behind churn or transaction drops, drills into subscription patterns, and delivers visual, actionable optimization strategies.

• The Email Agent (Natural-Language HTML Editing): Empowers marketing and ops teams to modify transactional HTML email templates dynamically. Users can command font changes, adjust CTA placements, or insert compliance language via natural text. The agent features real-time visual previews, version controls, and automated risk checks for sensitive words and broken links.

Extending AI to the Dev Environment via Model Context Protocol (MCP)

Recognizing that modern tech teams live inside their code editors, Subotiz is extending this natural-language capability directly into the developer workflow via the Subotiz MCP Server. Built on the open-source Model Context Protocol (MCP), the emerging standard for connecting AI assistants to secure data sources, Subotiz allows teams to manage their billing infrastructure straight from environments like Cursor, VS Code and Claude Desktop.

Through the Subotiz MCP Server, engineers and operations teams can query or create customer profiles, adjust pricing plans, audit live webhook event logs, inspect refund histories, and retrieve documentation using natural language commands. This eliminates the need to manually write boilerplate API scripts for routine troubleshooting and testing.

The real-world impact is already clear for lean, high-growth startups. In a recent deployment, a short-form digital content provider with zero dedicated back-end engineers utilized Subotiz’s embedded payment modules, automated compliance support, and MCP-driven testing environment to successfully simulate and validate its first subscription payment pipeline in just three days, all without writing a single line of custom code.

“Product iteration cycles have collapsed to days, but monetization remains trapped in weeks of configuration,” said Adam Mawdesley, Chief Revenue Officer of Subotiz. “Subotiz is closing that final gap. We are ensuring that business intent instantly translates into working payment and subscription infrastructure.”

The AI Agent Suite and Subotiz MCP Server are available now to all Subotiz users worldwide.

About Subotiz

Subotiz is a next-generation payment and revenue infrastructure platform designed for global digital businesses. By combining payments, subscription management, usage-based billing, tax and compliance automation, and fraud prevention into a unified platform, Subotiz enables SaaS, AI, eCommerce, and platform businesses to scale globally with greater operational efficiency and revenue flexibility. Learn more at Subotiz.

News Summary:

• Relativity has acquired Gavel, an AI-native legal technology company whose solutions are used by thousands of legal professionals to draft, review and automate legal work product.
• With the integration of Gavel, work product created in RelativityOne and Relativity aiR could be opened, drafted, edited, redlined and finalized inside Microsoft Word, with each edit syncing back to the matter in RelativityOne.
• The Gavel team joins Relativity, bringing deep expertise in AI-native drafting, document automation and the Microsoft Word experience that lawyers depend on.

CHICAGO, June 13, 2026  /PRNewswire/ — Relativity, a legal data intelligence company, today announced its acquisition of Gavel, an AI-native legal technology company whose solutions are used by thousands of legal professionals to draft, review and automate work product directly in Microsoft Word and on the web. Through the acquisition, Relativity plans to extend its AI platform for legal data intelligence into Microsoft Word, helping keep work product connected to the data and context behind matters.

“We believe that Relativity’s role as a driving force in legal AI innovation requires investing in the technology and people that create real value for our customers and partners. We’re delivering on that through Rel Labs, our partnership and startup investment program, and strategic moves like this one,” said Phil Saunders, CEO of Relativity. “This acquisition enhances our ability to support a wider arc of legal work, in the place where lawyers spend most of their time. The Gavel team is exceptional, and we’re excited to come together and bring what they’ve built to the Relativity community.”

RelativityOne serves as the AI platform for legal data intelligence and the system of action where teams organize, analyze and act on the evidence at the heart of their most important matters. Yet the documents that follow from that work—motions, briefs and contracts—have historically remained in Microsoft Word, separate from the data and context that shaped them. With Relativity’s integration of Gavel, that work should no longer need to leave the platform, deepening attorney engagement with RelativityOne across the full matter lifecycle.

Work product generated by Relativity aiR for Case Strategy, aiR Assist and more could become editable directly in Microsoft Word, enabling lawyers to refine, route for comments and redlines, and finalize documents within their natural workflow. Every change could sync back to the matter in RelativityOne, creating a more connected experience where legal intelligence and the work product it shapes move together.

“With Gavel, drafting and collaboration happen directly in Microsoft Word. Once integrated with RelativityOne, that work could happen against the full context of the matter, with edits syncing back to the platform,” said Chris Brown, Chief Product Officer at Relativity. “We would be taking the system of action that lawyers already rely on and extending it into the surfaces where they actually do the work.”

Gavel was founded by Dorna Moini, a former associate at Sidley Austin LLP, who began building document automation tools for pro bono clients and eventually grew Gavel into an AI-native platform used by legal teams worldwide. Gavel’s Chief Technology Officer, Pierre Martin, joined the company in 2022, bringing deep experience at the intersection of AI and enterprise software, with previous leadership and executive roles at Microsoft, Amazon and high-growth startups. Now, the Gavel team joins Relativity with a shared commitment to helping legal professionals work smarter, move faster and act with greater confidence.

“This is an exciting next chapter for Gavel employees and our customers,” said Dorna Moini, Founder and CEO of Gavel. “Joining Relativity gives us an unrivaled opportunity to scale our shared vision for the industry, build faster and bring our technology to more legal teams. Relativity’s footprint, data platform and deep trust across the legal industry will help us take everything we’ve built at Gavel to the next level.”

Law firms and organizations across 28 countries use Gavel to draft, edit and automate legal work product with a combination of generative AI and rules-based workflows. Operating in Microsoft Word and on the web, Gavel supports drafting, contract review, redlining and analysis with contextual guidance grounded in legal norms and playbooks, helping work product stay consistent with firm standards and connected to the most relevant information.

Relativity’s immediate focus is on thoughtful integration and continuity for customers. The company intends to maintain Gavel’s regular operations while bringing its capabilities into RelativityOne over time.

About Relativity 
Relativity is a leading legal data intelligence company that builds technology to help users organize data, discover the truth, and act on it. Its extensible, AI cloud platform, RelativityOne, transforms complex data into actionable insights at massive scale for litigation, investigations, regulatory inquiries, data breach responses, and other legal use cases. The world’s largest law firms and corporations, government agencies, and a robust network of channel partners rely on Relativity’s legal AI software to securely surface and manage the most relevant and impactful information in their matters. The company also expands access to technology by providing its platform at no cost to academic institutions through its Relativity Academic program and to organizations supporting pro bono legal work through its Justice for Change initiative. 

CONTACT: PR@relativity.com

LOS ANGELES, June 13, 2026 /PRNewswire/ — Insta360 has filed two countersuits against DJI in the U.S., asserting five utility patents covering technology used in gimbal and 360-degree cameras.

The company asserts that DJI infringed its patents relating to gimbal stabilization, gimbal directional control, camera smooth stabilization, telemetry overlay, and panoramic video stabilization. These technologies are incorporated into several major DJI products, including the Osmo Pocket series, Ronin/RS series, Osmo Mobile series, and Osmo 360.

“At Insta360, we prefer to let our products do the talking. But we are not afraid of a legal battle when challenged,” said JK Liu, Founder of Insta360. “We are fully committed to protecting our innovations and will take decisive action to defend our intellectual property from infringement.”

These countersuits are a direct response to patent lawsuits initiated by DJI on June 10—the day Insta360 launched its Luna Ultra camera. DJI’s legal action seeks a permanent injunction to ban Luna Ultra from the U.S. market. 

Insta360 categorically rejects DJI’s infringement claims regarding the new Luna Ultra camera, emphasizing the device’s unique engineering footprint.

“Luna Ultra is the result of years of independent R&D, not a response to any competitor’s product,” added Liu. “Development began in 2020, with earlier Insta360 products including the ONE R, Link Series webcams, and Flow Series gimbals helping shape the technology and design direction behind Luna Ultra. DJI filing lawsuits on the same day we launched Luna Ultra speaks volumes—exposing their fear of competition from a highly competitive product.”

Initial consumer response has been strong, with Luna Ultra seeing significant demand in North America and ranking as the top seller in Amazon’s camcorder category in the U.S. over its first 24 hours of availability. Insta360 remains fully committed to defending its IP portfolio while working to ensure the continued availability of its products for creators worldwide.

Insta360

With a “Think bold” mindset, Insta360 empowers people to capture and share their lives in extraordinary ways. Recognized as a market leader and innovator, Insta360’s vast lineup includes the world’s best-selling 360 cameras in the X Series, the pocket-sized GO Series for everyday capture, as well as an extensive range of action cameras, gimbals, webcams, and professional photography solutions. With intuitive, AI-powered software, Insta360 simplifies the creative process, allowing users to focus on storytelling without technical barriers. Insta360 is dedicated to helping a new generation of athletes, creatives, travelers and professionals bring their ideas to life.

For more details visit: http://www.insta360.com
About the Think Bold Fund: https://www.insta360.com/ThinkBoldFund
Read our blog: https://www.insta360.com/blog
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• Heart symptoms continue to be dismissed or mistaken for other conditions, such as anxiety, new global patient-led research reveals.
• Findings were presented at the European Society of Cardiology’s ACNAP Congress 2026, organised by the Association of Cardiovascular Nursing & Allied Professions, the leading congress for nurses and allied professionals committed to advancing patient-centred cardiovascular care.

GALWAY, Ireland, June 13, 2026 /PRNewswire/ — Global Heart Hub, the international alliance of heart patient organisations, has released insights from their latest patient-led qualitative research study exploring women’s experiences with cardiovascular disease. The findings reveal that women are slow to seek medical help and there are ongoing gaps in the recognition and diagnosis of heart disease in women despite it remaining the leading cause of death among women globally.

The study, IPEC2 (Insights & Patient Experiences with Cardiovascular Disease), collected patient experience data from women across eight countries and includes women with elevated low-density lipoprotein cholesterol (LDL-C), elevated LP(a), heart valve disease and cardiomyopathy. The research explored women’s experiences of heart disease; their awareness and recognition of cardiovascular symptoms; barriers across the care pathway and assessed the burden of managing heart disease on women’s lives. The Global Heart Hub study is guided by both an independent Steering Committee and Review Committee. The committees are comprised of people with lived experience, patient organisation leaders and international clinical experts.

ACNAP 2026

IPEC2 preliminary findings were presented at the European Society of Cardiology’s ACNAP Congress 2026 on 12 June, focusing on women with elevated low-density lipoprotein cholesterol who were hospitalised at least once for a cardiac event (heart attack, stroke, or unstable angina). Uncontrolled elevated LDL cholesterol is a primary driver of atherosclerotic cardiovascular disease (ASCVD), the leading cause of death in women across the world. The IPEC2 preliminary findings included women aged 18 years or older in the US, Canada, China and Italy.

“We now have incredible therapies to deal with high LDL-C ‘bad cholesterol’. However, the study findings highlight that women may not receive a timely diagnosis and, therefore, cannot access any treatment. The reasons are due to delays in women seeking care, frequently putting others (family) before their own health. In addition, the findings describe delays in diagnosis due to under-recognition of symptoms, life factors and clinician bias. This means that women continue to be treated later in the disease progression, sometimes at the point of their life-threatening cardiac event, which often diminishes their opportunity for better outcomes,” says Professor Vijay Kunadian, Professor of Interventional Cardiology and Cardiovascular Medicine, Newcastle University & Newcastle Hospitals, UK; and Member of IPEC2’s Steering Committee.

The preliminary findings reveal that women across every focus group experienced perceived bias in their healthcare journey, sharing their perceptions of times in their diagnosis and treatment journey where others indicated they were “too young” or “not the type” for cardiovascular disease. The gender bias in diagnosis is also evident, with women reporting that their cardiovascular disease symptoms were commonly misdiagnosed as other non-cardiac conditions, most frequently anxiety. Women described a broad and varied range of cardiovascular symptoms, including symptoms beyond those reported in guidelines. These findings highlight the need for improved symptom recognition and patient education to support earlier identification and more equitable, patient-centred care across cardiovascular settings.

“Cardiovascular disease is the leading cause of death among women, and the IPEC2 findings confirm that women continue to experience late, missed or misdiagnosed heart disease, often compounded by fragmented care. Women often experience symptoms that differ from those traditionally described in men, yet these are frequently not recognised as cardiac. We need to think ‘heart first’ for every woman, everywhere,” says Neil Johnson, Executive Director, Global Heart Hub.

IPEC2 seeks to deepen understanding of women’s experiences with cardiovascular disease by collecting robust patient experience data. The research guides recommendations towards improving patient care for women. The preliminary findings highlighted the need for improved symptom recognition and patient education to support earlier identification and more equitable, patient-centred care across cardiovascular settings.

Learn more about IPEC2: globalhearthub.org/ipec2 

Global Heart Hub’s Insights and Patient Experiences with Cardiovascular Disease (IPEC) study is a patient-led initiative made possible with the support of Amgen Inc., Daiichi Sankyo Europe, and Novartis Pharmaceuticals Corporation.

About Global Heart Hub:

Established in 2019 and headquartered in Ireland, Global Heart Hub (GHH) is the first international non-profit organisation established to provide a voice for those living with, or affected by, cardiovascular disease. We are an alliance of 150+ heart patient organisations across 40+ countries, aiming to create a unified global voice for those living with or affected by heart disease. Learn more: globalhearthub.org

• Heart symptoms continue to be dismissed or mistaken for other conditions, such as anxiety, new global patient-led research reveals.
• Findings were presented at the European Society of Cardiology’s ACNAP Congress 2026, organised by the Association of Cardiovascular Nursing & Allied Professions, the leading congress for nurses and allied professionals committed to advancing patient-centred cardiovascular care.

GALWAY, Ireland, June 13, 2026 /PRNewswire/ — Global Heart Hub, the international alliance of heart patient organisations, has released insights from their latest patient-led qualitative research study exploring women’s experiences with cardiovascular disease. The findings reveal that women are slow to seek medical help and there are ongoing gaps in the recognition and diagnosis of heart disease in women despite it remaining the leading cause of death among women globally.

The study, IPEC2 (Insights & Patient Experiences with Cardiovascular Disease), collected patient experience data from women across eight countries and includes women with elevated low-density lipoprotein cholesterol (LDL-C), elevated LP(a), heart valve disease and cardiomyopathy. The research explored women’s experiences of heart disease; their awareness and recognition of cardiovascular symptoms; barriers across the care pathway and assessed the burden of managing heart disease on women’s lives. The Global Heart Hub study is guided by both an independent Steering Committee and Review Committee. The committees are comprised of people with lived experience, patient organisation leaders and international clinical experts.

ACNAP 2026

IPEC2 preliminary findings were presented at the European Society of Cardiology’s ACNAP Congress 2026 on 12 June, focusing on women with elevated low-density lipoprotein cholesterol who were hospitalised at least once for a cardiac event (heart attack, stroke, or unstable angina). Uncontrolled elevated LDL cholesterol is a primary driver of atherosclerotic cardiovascular disease (ASCVD), the leading cause of death in women across the world. The IPEC2 preliminary findings included women aged 18 years or older in the US, Canada, China and Italy.

“We now have incredible therapies to deal with high LDL-C ‘bad cholesterol’. However, the study findings highlight that women may not receive a timely diagnosis and, therefore, cannot access any treatment. The reasons are due to delays in women seeking care, frequently putting others (family) before their own health. In addition, the findings describe delays in diagnosis due to under-recognition of symptoms, life factors and clinician bias. This means that women continue to be treated later in the disease progression, sometimes at the point of their life-threatening cardiac event, which often diminishes their opportunity for better outcomes,” says Professor Vijay Kunadian, Professor of Interventional Cardiology and Cardiovascular Medicine, Newcastle University & Newcastle Hospitals, UK; and Member of IPEC2’s Steering Committee.

The preliminary findings reveal that women across every focus group experienced perceived bias in their healthcare journey, sharing their perceptions of times in their diagnosis and treatment journey where others indicated they were “too young” or “not the type” for cardiovascular disease. The gender bias in diagnosis is also evident, with women reporting that their cardiovascular disease symptoms were commonly misdiagnosed as other non-cardiac conditions, most frequently anxiety. Women described a broad and varied range of cardiovascular symptoms, including symptoms beyond those reported in guidelines. These findings highlight the need for improved symptom recognition and patient education to support earlier identification and more equitable, patient-centred care across cardiovascular settings.

“Cardiovascular disease is the leading cause of death among women, and the IPEC2 findings confirm that women continue to experience late, missed or misdiagnosed heart disease, often compounded by fragmented care. Women often experience symptoms that differ from those traditionally described in men, yet these are frequently not recognised as cardiac. We need to think ‘heart first’ for every woman, everywhere,” says Neil Johnson, Executive Director, Global Heart Hub.

IPEC2 seeks to deepen understanding of women’s experiences with cardiovascular disease by collecting robust patient experience data. The research guides recommendations towards improving patient care for women. The preliminary findings highlighted the need for improved symptom recognition and patient education to support earlier identification and more equitable, patient-centred care across cardiovascular settings.

Learn more about IPEC2: globalhearthub.org/ipec2 

Global Heart Hub’s Insights and Patient Experiences with Cardiovascular Disease (IPEC) study is a patient-led initiative made possible with the support of Amgen Inc., Daiichi Sankyo Europe, and Novartis Pharmaceuticals Corporation.

About Global Heart Hub:

Established in 2019 and headquartered in Ireland, Global Heart Hub (GHH) is the first international non-profit organisation established to provide a voice for those living with, or affected by, cardiovascular disease. We are an alliance of 150+ heart patient organisations across 40+ countries, aiming to create a unified global voice for those living with or affected by heart disease. Learn more: globalhearthub.org