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RETRANSMISSION: RZOLV Reports Approximately 97.0% Gold Recovery on Complex Copper-Gold Ore Without Pretreatment, Highlighting Potential to Simplify Flowsheets Versus Cyanide

New test results support RZOLV as a potential breakthrough solution for complex gold-copper ores, with the potential to avoid cyanide-related SART complexity

Vancouver, British Columbia – Newsfile Corp. – April 16, 2026 – RZOLV Technologies Inc. (TSXV: RZL) (OTCQB: RZOLF) (FSE: S711) (“RZOLV” or the “Company”) is pleased to report the results of recent metallurgical test work in which the Company achieved approximately 97.0% gold recovery on a complex copper-gold ore using the RZOLV formula, without pretreatment.

The tested material graded approximately 9.6 g/t gold and 2.12% copper and is hosted within an alkaline gold-copper porphyry system. The gold mineralization is interpreted to be low-sulphidation epithermal mineralization.

The Company believes these results are significant because copper-bearing gold ores are widely recognized as challenging for conventional cyanide processing. SGS technical publications note that copper minerals can materially increase cyanide consumption and complicate solution management, and that where cyanide-soluble copper becomes significant, operators may consider adding a SART circuit to precipitate copper sulphide and recover cyanide for recycle. By achieving approximately 97.0% gold recovery on this copper-bearing ore without pretreatment, RZOLV believes the test work supports the potential for a simpler and potentially lower-cost processing route relative to a conventional cyanide alternative on similar mineralization.

RZOLV Technologies conducted bottle roll leach tests on the subject material to evaluate performance under controlled laboratory conditions. The test was conducted at 20% pulp density on a 150 g sample crushed to a target size of -500 µm and run for 168 hours with solution sampling at regular intervals.

Figure 1 — Gold Recovery Over Time (Test 137-1, Cu/Au Sample – RZOLV 168 Hours)

To view an enhanced version of this graphic, please visit:
https://images.newsfilecorp.com/files/11597/292813_rzolv.jpg

Table 1 — Gold Recovery Over Time (Cu/Au Sample – RZOLV 168 Hours)

Test Assayed
Head Au
(g/t)
Calculated
Head Au
(g/t)
Final
Residue Au
(g/t)
Recovery
@24h
Recovery
@48h
Recovery
@72h
Recovery
@96h
Recovery
@120h
Recovery
@168h
137 9.5 9.6 0.29 33.95% 79.67% 87.90% 91.27% 91.35% 96.97%

Analytical Basis

Testing was carried out at ambient laboratory temperature. Process pH and oxidation-reduction potential were monitored during the tests. Solution samples were collected at closely spaced intervals during the initial 4 hours to characterize early-stage kinetics, followed by additional sampling at 24, 48, 72, 96, and 120 hours.

Gold extraction values reported herein are based on internal solution and residue calculations generated during the test program. Final solid residues from the test were subsequently submitted to ALS Laboratories for independent assay verification. Results are presented above.

“This is an important result for RZOLV because it goes well beyond recovery alone,” said Duane Nelson, President & CEO of RZOLV Technologies. “To achieve this high gold recovery on a copper-bearing complex ore without pretreatment suggests that RZOLV may offer a practical alternative in mineral systems where cyanide can become penalized by copper. If supported by further work, this could translate into simpler plant design, lower capital costs, lower reagent penalty, and the potential to avoid the need for a costly SART circuit that might otherwise be required under a cyanide flowsheet.”

The Company believes the implications of this result may include:

  • Potential flowsheet simplification, by reducing or potentially eliminating the need for a separate copper-cyanide management circuit;
  • Lower capital intensity, through the possible avoidance of a SART plant and related supporting infrastructure;
  • Reduced operating complexity, including fewer unit operations and less process management associated with copper-cyanide recycling;
  • Improved project economics, particularly for lower-grade or copper-bearing gold ores where processing costs are highly sensitive to reagent consumption and circuit complexity; and
  • Expanded market relevance for RZOLV, further supporting its potential application in ore types that can fall within conventional cyanide “penalty” windows.

The Company further notes that the absence of pretreatment in this test work is particularly encouraging. Pretreatment steps can add substantial cost, time, technical complexity and permitting burden to a project. Demonstrating high gold recovery without such steps may improve the commercial attractiveness of RZOLV for certain complex ore bodies.

These are ore types where conventional cyanide does not merely underperform environmentally, but can become economically burdened by complexity, copper interference, pretreatment requirements, or downstream circuit additions. If this result is supported by further work, it suggests that RZOLV may not simply be an alternative to cyanide, but a superior solution in selected copper-bearing gold systems. The Company intends to continue metallurgical work to further evaluate recovery performance, reagent optimization, copper deportment, process economics and scale-up parameters across broader sample sets and operating conditions.

Exchange Disclaimer

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

About RZOLV Technologies Inc.
RZOLV Technologies Inc. is a clean-technology company advancing a new generation of hydrometallurgical chemistry designed to transform how precious and critical metals are recovered from ores, concentrates, and renewables. The Company is developing proprietary, non-cyanide solutions intended to unlock value from complex materials where conventional methods can be limited.

Its flagship technology, RZOLV™, is a proprietary, water-based dissolution system designed to achieve strong recovery performance without the toxicity, permitting burden, and legacy liabilities associated with conventional cyanide-based processes. By operating in a broader and more controllable chemical window, RZOLV™ has the potential to recover precious and critical metals from challenging feedstocks and support a safer, more sustainable path forward for the mining and resource recovery industries.

For more information, please visit https://www.rzolv.com.

For further information, please contact:
Duane Nelson
President & CEO
RZOLV Technologies Inc.
Tel: +1-604-332-2662
Email: duane@rzolv.com

Forward-Looking Statements
This news release contains forward-looking statements within the meaning of applicable securities laws. Forward-looking statements include, but are not limited to, statements regarding the potential implications of the reported metallurgical results, including possible reductions in capital cost, operating complexity, pretreatment requirements, and the potential to reduce or eliminate the need for a SART circuit under certain conditions, as well as statements regarding future testing, scale-up, commercial applicability and economic performance. Forward-looking statements are based on management’s current expectations, estimates, assumptions and beliefs as of the date hereof. Actual results may differ materially from those expressed or implied by such statements due to a variety of risks, uncertainties and other factors, including the possibility that further test work does not confirm current results, that ore characteristics vary, that scale-up performance differs from laboratory results, and that economic, technical, regulatory or market conditions change. Readers are cautioned not to place undue reliance on forward-looking statements. The Company undertakes no obligation to update or revise forward-looking statements except as required by applicable law.

The issuer is solely responsible for the content of this announcement.

The 2026 World Internet Conference Asia-Pacific Summit Concludes Successfully


HONG KONG SAR – Media OutReach Newswire – 16 April 2026 – On April 14, the two-day 2026 World Internet Conference Asia-Pacific Summit, themed “Digital and Intelligent Empowerment for Innovative Development — Jointly Building a Community with a Shared Future in Cyberspace,” came to a successful conclusion.

The 2026 World Internet Conference Asia-Pacific Summit Concludes Successfully

This year marks the second consecutive time that Hong Kong has hosted the international conference. Approximately 1,000 participants attended, including ministerial-level officials from government departments, senior representatives of international organizations, diplomatic envoys to China, leaders from prominent internet enterprises, as well as experts and scholars from more than 50 countries and regions.

John Lee, Chief Executive of the Hong Kong Special Administrative Region, stated that the successful hosting of the summit fully demonstrates Hong Kong’s unique advantages under the “One Country, Two Systems” framework. The HKSAR Government is accelerating the development of innovation and technology, with artificial intelligence as a key pillar. Hong Kong ranks among the world’s leading economies in AI readiness and is committed to harnessing the power of AI in a responsible and inclusive manner.

Zhuang Rongwen, Chairman of the World Internet Conference and Director of the Cyberspace Administration of China, noted that the summit aims to align with the accelerating trends of digitalization, networking, and intelligent transformation. It seeks to build consensus and pool strengths across sectors, leveraging new achievements and cooperation outcomes in the digital and intelligent fields to make greater contributions toward a brighter digital future for the Asia-Pacific region.

On the afternoon of April 13, the main forum of the 2026 World Internet Conference Asia-Pacific Summit, along with the Distinguished Contributors Ceremony, was held in Hong Kong.

Wang Jingtao, Deputy Director of the Cyberspace Administration of China, and Francis Gurry, Vice Chairman of the World Internet Conference and former Director General of the World Intellectual Property Organization, attended and delivered keynote speeches. Ren Xianliang, Secretary-General of the World Internet Conference, was also present.

Wang Jingtao pointed out that the global wave of intelligent transformation is surging, with breakthroughs in artificial intelligence emerging collectively. He emphasized the need to build consensus and deepen cooperation to address the critical question of how digital technologies can better benefit humanity. He proposed four key measures:

  1. Uphold openness and cooperation to expand the digital economy;
  2. Promote inclusiveness and shared benefits to bridge digital and intelligence divides;
  3. Strengthen coordinated governance to build a fair and equitable cyberspace order;
  4. Reinforce security foundations to safeguard cyberspace safety.

Francis Gurry stated that digital and intelligent empowerment means enabling individuals, enterprises, institutions, and diverse cultural and economic actors to adapt to the digital and AI environment, seize social and economic opportunities, and share in development dividends. He emphasized that all stakeholders bear important responsibilities in this process. The Distinguished Contributors Ceremony was established to honor individuals and enterprises that have driven the development of digital and intelligent technologies, recognizing both their technological excellence and their deep concern for the societal impact of technological transformation.

Paul Chan, Financial Secretary of the HKSAR Government, and Sun Dong, Secretary for Innovation, Technology and Industry, also attended and delivered speeches. Other distinguished participants included Wu Jianping, Academician of the Chinese Academy of Engineering and Director of the Zhongguancun Laboratory; Nii Quaynor, Chairman of Ghana Dot Com and recipient of the 2024 Distinguished Contribution Award; and Kilnam Chon, Honorary Professor at KAIST and also a 2024 award recipient. Wu Dong, Chief Engineer of the Cyberspace Administration of China, also attended the event.

The event invited individuals, enterprises, and prominent figures who have made outstanding contributions to the development of the global internet. Through keynote speeches, roundtable discussions, and personal narratives, participants shared their practices and insights on building a community with a shared future in cyberspace. The program featured four thematic sections: “Tribute to the Connectors of the World,” “Tribute to Technological Innovators,” “Tribute to Digital Pioneers — Hong Kong Dialogue,” and “Tribute to Technology for Good.” Participants also explored future directions and opportunities for artificial intelligence.

During the event, the launch of the 2026 World Internet Conference Leading Science and Technology Awards and the global call for case studies on jointly building a community with a shared future in cyberspace were announced. The launch ceremony for the 2026 Distinguished Contribution Awards was also held.

On April 14, six sub-forums on different themes were held in Hong Kong. Participants engaged in in-depth discussions on topics including intelligent agent innovation and applications, digital finance, AI safety governance, smart livelihoods, digital health, and the digitalization and dissemination of classical texts.

On the same day, ten think tanks participating in the World Internet Conference Think Tank Cooperation Program released a series of research outcomes at the Smart Livelihoods and Digital Finance Forum of the 2026 Asia-Pacific Summit.

The 2026 World Internet Conference Asia-Pacific Summit was organized by the World Internet Conference, hosted by the Hong Kong Special Administrative Region Government, and co-organized by the Innovation, Technology and Industry Bureau of the HKSAR Government.

Hashtag: #WorldInternetConference

The issuer is solely responsible for the content of this announcement.

STRADVISION Enables Scalable ADAS Deployment in India’s Commercial Vehicle Market with Efficient AI Perception

SEOUL, South Korea, April 16, 2026 /PRNewswire/ — STRADVISION, a company specializing in AI-based vision perception technology for automotive applications, today announced that a global commercial vehicle OEM has selected SVNet for deployment across its India vehicle lineup. The program targets fleet-scale ADAS deployment in India’s commercial vehicle segment, where cost-efficient and reliable perception software is critical to broad adoption.

India’s commercial vehicle market presents a distinct set of requirements for ADAS deployment. Delivering reliable perception at scale requires software capable of running on low-cost, resource-constrained hardware while maintaining stable performance across diverse and high-density traffic conditions. For commercial vehicle operators, where uptime and operating efficiency are central concerns, both technical performance and deployment economics must be addressed.

SVNet is designed to meet these requirements. The software delivers stable object detection and classification across the road conditions characteristic of the Indian market, including mixed-traffic environments with two- and three-wheelers, pedestrians, and other vulnerable road users, while operating within the compute budgets suited to commercial-vehicle platforms. This enables OEMs to deploy core ADAS functions, including automatic emergency braking, forward collision warning, and lane departure warning, across multiple vehicle models and configurations from a single software stack.

The program is structured for deployment across multiple vehicle models, enabling the OEM to standardize a single perception platform while adapting to model-specific hardware configurations. With approximately five million cumulative SVNet units deployed globally, STRADVISION brings the production scale and software maturity that high-volume commercial programs require.

Philip Vidal, CBO of STRADVISION, said, “India’s commercial vehicle segment is one of the most consequential ADAS markets opening right now. The scale of the fleet, the complexity of the traffic environment, and the cost requirements make it a genuine test of whether perception software can perform where it matters most. SVNet was built for exactly this kind of deployment, and this program is a strong validation of that.”

This development reflects a broader shift in the automotive industry, where the focus of ADAS competition is expanding from performance to efficiency and scalability. STRADVISION will continue to support OEMs with perception solutions that can be applied across diverse vehicle platforms and market conditions.

About STRADVISION

Founded in 2014, STRADVISION is an automotive industry pioneer in artificial intelligence-based vision perception technology for vehicles. The company is accelerating the advent of fully autonomous vehicles by making Autonomous Driving and ADAS features available at a fraction of the market cost compared with competitors. STRADVISION’s SVNet is being deployed on various vehicle models in partnership with OEMs; can power ADAS and autonomous vehicles worldwide; and is serviced by over 300 employees in Seoul, San Jose, Detroit, Tokyo, Shanghai, and Dusseldorf. STRADVISION has been honored with Frost & Sullivan’s 2022 Global Technology Innovation Leadership Award, the Gold Award at the 2022 and 2021 AutoSens Awards for Best-in-Class Software for Perception Systems, the 2020 Autonomous Vehicle Technology ACES Award in Autonomy (software category), and 2025 Top SME Innovator by CLEPA for Breakthrough AI 3D Perception Network Technology. In addition, STRADVISION and its software have achieved TISAX’s AL3 standard for information security management, as well as being certified to the ISO 9001:2015 for Quality Management Systems and ISO 26262 for Automotive Functional Safety.

www.stradvision.com 

Nexteer to Debut M³ Theme at Auto China 2026

BEIJING and SUZHOU, China, April 16, 2026 /PRNewswire/ — Nexteer Automotive (HK 1316), a global leader in motion control technologies, will showcase its latest innovations at the 19th Beijing International Automotive Exhibition (Auto China 2026). Under the official theme “Future of Intelligence,” the exhibition will be held from April 24th to May 3rd, 2026 at the China International Exhibition Center (Shunyi) and the Capital International Exhibition Center of China in Beijing. Nexteer invites all guests to visit its booth W1B03 in Hall W1.

Motion, Millisecond, Mastery
At this year’s auto show, Nexteer will present its M³ theme, built around three core pillars: Motion, Millisecond, and Mastery — representing motion, precision, and trust. Together, they capture the essence of Nexteer’s strength as a motion control expert: delivering millisecond-level responsiveness for precise vehicle control, backed by a century of engineering heritage that earns the trust of OEMs and drivers alike. The M³ theme reflects Nexteer’s deep commitment to motion control — from the fundamental precision of vehicle dynamics to agile, millisecond-fast decision-making. Leveraging a century of hands-on expertise, Nexteer continues to deliver safe, reliable, and trustworthy motion control solutions to OEMs and end customers worldwide.

3 Highlight Displays: A Panoramic Showcase of Core Strength in Motion-by-WireTM Technologies
Nexteer’s booth will feature three key exhibits that demonstrate the company’s integrated innovation capabilities in Motion‑by‑Wire™ technology:

  • MotionbyWire™ Technology Portfolio – Integrating Steer‑by‑Wire (SbW), Rear‑Wheel Steering (RWS), Brake‑by‑Wire (EMB) and the Motion IQ™ Software Suite into a comprehensive, integrated motion control solution. Visitors can experience the breakthrough innovations of next‑generation vehicles firsthand through a driving simulator, and feel enhanced safety, comfort and overall vehicle performance.
  • Motion X – A multimedia, hands‑on display that brings the dynamic capabilities of Nexteer’s EMB (Electro‑Mechanical Brake) system to life. Visitors can immerse themselves in the braking experience enabled by the EMB system’s independent four‑wheel precision control and millisecond‑level responsiveness across a variety of driving scenarios.
  • Motion Module – An integrated static display that clearly showcases the EMB system’s compact architecture and vehicle‑level packaging solutions, highlighting the efficient integration and flexible configuration of each key module.

Additionally, Nexteer will showcase its Steer-by-Wire (SbW) product and technology portfolio. It offers flexible combinations of Hand Wheel Actuators and Road Wheel Actuators to meet the diverse needs of different vehicle models and driving scenarios, delivering an end-to-end technology chain from steering feel feedback to precise wheel control. Nexteer’s Steer-by-Wire technology is transitioning from innovation to production, with multiple OEM programs scheduled to launch across global markets within the next 12 months.

From Steering Focus to Domain Integration: Nexteer Honors 120 Years of Engineering Heritage with Integrated Steering and Braking Technologies
During the Auto Show, Nexteer will hold a press conference to share its latest technological breakthroughs and production progress in Steer‑by‑Wire and Brake‑by‑Wire — marking a milestone as the company celebrates its 120th anniversary. Since 1906, Nexteer has remained dedicated to the innovation and deep cultivation of motion control technology. Rooted in a century of engineering expertise, the company has evolved from a pure‑play steering systems developer to a provider of advanced, integrated steering and braking solutions. This ongoing commitment to innovation enables Nexteer to deliver leading chassis integration solutions that continue to set the benchmark for the industry.

We sincerely invite you to visit Nexteer at Booth W1B03, Hall W1, China International Exhibition Center (Shunyi) in Beijing, to experience firsthand our latest technological innovations and integration practices in the field of motion control.

ABOUT NEXTEER AUTOMOTIVE
Nexteer Automotive (HK 1316) is a global leading motion control technology company accelerating mobility to be safe, green and exciting. Our innovative portfolio supports Motion-by-WireTM chassis control, including electric and hydraulic power steering systems, steer-by-wire and rear-wheel steering systems, steering columns and intermediate shafts, driveline systems, software solutions and brake-by-wire. Celebrating 120 years of automotive innovation in 2026, Nexteer builds on a strong legacy of engineering excellence while continuing to shape the future of mobility. The company solves motion control challenges across all megatrends – including electrification, software/connectivity, ADAS/automated driving and shared mobility – for global and domestic OEMs around the world including BMW, Ford, GM, RNM, Stellantis, Toyota and VW, as well as automakers in India and China including BYD, Xiaomi, ChangAn, Li Auto, Chery, Great Wall, Geely, Xpeng and others. www.nexteer.com  

Links to Nexteer Media Center

 

Shipsy Named a Niche Player in the 2026 Gartner® Magic Quadrant™ and recognized in Critical Capabilities for Transportation Management Systems

AMSTERDAM, April 16, 2026 /PRNewswire/ — Shipsy, a leading provider of end-to-end AI-native solutions for logistics, today announced its recognition as a Niche Player in the 2026 Gartner® Magic Quadrant™ for Transportation Management Systems (TMS), for the third consecutive year.

Unlike traditional TMS platforms that surface data but leave execution to human teams, Shipsy is built as an AI-native system of action — detecting exceptions, triggering corrective workflows, and executing across planning, dispatch, customer experience, and freight settlement within a single platform.

We believe, this approach to deeply embed AI in workflows and help drive outcomes, across the enterprise has helped Shipsy grow faster than other vendors expanding its average contract value as well as its ARR in the last three years.Today Shipsy counts 9 Fortune 500 companies as customers, as well as 18 category leaders across retail and eCommerce, food and beverage and others.

Shipsy’s growing presence in Europe with local teams has helped it deepen its relationships with enterprise clients, offering a closer, more localized outcome-first engagement model. .

“Logistics has long run on systems that show you what went wrong after the fact. We’re building the layer that closes the loop: where AI detects the exception, coordinates across carriers, drivers, and customers, and resolves it, with humans governing the edge cases that require judgment. To us, being named in the Gartner Magic Quadrant for the third consecutive year reflects the trust of the enterprises that have made this transition with us,” said Soham Chokshi, Co-Founder and CEO, Shipsy.

Shipsy recently launched AgentFleet, an AI-native digital workforce of purpose-built agents- including Clara for customer exception management, Nexa for autonomous freight settlement, Astra for enhanced driver experience, and Vera for dispute resolution— that continuously observe-decide-act for closed loop and execute corrective actions across systems, reducing the manual coordination overhead for enterprise logistics teams.

To learn more about Shipsy’s Gartner recognition or to request access to the full report, visit www.shipsy.ai.

Gartner Disclaimer:

Gartner and Magic Quadrant are trademarks of Gartner, Inc., and/or its affiliates. Gartner does not endorse any vendor, product or service depicted in its research publications, and does not advise technology users to select only those vendors with the highest ratings or other

designation. Gartner research publications consist of the opinions of Gartner’s research organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose. GARTNER is a registered trademark and service mark of Gartner, Inc. and/or its affiliates in the U.S. and internationally. MAGIC QUADRANT is a registered trademark of Gartner, Inc. and/or its affiliates and is used herein with permission. All rights reserved.

Gartner, Magic Quadrant for Transportation Management Systems, By Brock Johns, Oscar Sanchez Duran, Manav Jain, 30 March 2026.

About Shipsy

Shipsy is redefining the multi-trillion-dollar logistics industry with its AI-native Enterprise Transportation Management Platform, helping 9 Fortune 500 companies and marquee global enterprises across logistics, retail, and pharmaceuticals transition to autonomous supply chains. With Agentic AI at its core, Shipsy drives enterprise-wide transformation for 250+ customers in 30+ countries.Shipsy operates from global offices across London, Amsterdam, Riyadh, Dubai, Singapore, and India. Learn more at www.shipsy.ai.

 

Orthocell Secures Approval to sell Remplir™ to the U.S. Department of Defence Hospital Network

  • Orthocell receives approval for Remplir™ to be used across the United States Department of Defence (DoD) and Veterans Affairs (VA) hospital networks, comprising:
    • 51 DoD military hospitals; and
    • 170 Veterans Affairs (VA) medical centres
  • For context, Orthocell has already secured 32 Value Analysis Committee (VAC) approvals providing access to over 115 hospitals, with a further 57 VAC applications currently pending approval[1]
  • Orthocell will now leverage its existing U.S. distributor network to target military and VA surgeons operating within these hospital systems. The Company’s distributor network currently covers 17 states
  • This approval comes at a time when Orthocell is seeing clear evidence of increasing commercialisation and revenue momentum in the U.S. market
  • Remplir has already demonstrated its value in conflict-related injuries in Ukraine, with multiple surgical procedures performed, highlighting its suitability for the types of trauma commonly encountered within military healthcare systems

PERTH, Australia, April 16, 2026 /PRNewswire/ — Regenerative medicine company Orthocell Limited (ASX: OCC, “Orthocell” or the “Company”) is pleased to announce it has secured approval for its Remplir™ nerve repair device to be used across the United States Department of Defence (DoD) and Veterans Affairs (VA) hospital networks.

This approval provides access to approximately 51 DoD military hospitals and 170 VA medical centres across the United States, representing a significant milestone in expanding Orthocell’s access to the U.S. market.

Orthocell’s established U.S. distributor network, which currently covers 17 states, will now target military and VA surgeons operating within these hospital systems. A significant portion of these facilities could be serviced by the Company’s existing distribution footprint, supporting efficient market penetration.

This expansion into the defence setting follows the recent clinical use of Remplir in 23 surgical procedures on injured soldiers in Ukraine, across both primary and secondary nerve repair applications.

The Ukraine experience demonstrates the real-world performance of Remplir in a conflict environment and highlights key attributes of the device, including its portability, ease of use, and suitability for treating major traumatic injuries commonly encountered in military settings.

Orthocell believes this validation further supports Remplir’s applicability within defence healthcare systems and reinforces its potential to address the needs of military surgeons treating complex nerve injuries.

Orthocell Managing Director Paul Anderson said: “Securing access to the U.S. Department of Defence and Veterans Affairs hospital networks is a significant milestone for Orthocell and a major step forward in our U.S. commercial strategy.

This approval enables us to engage directly with military and VA surgeons treating complex nerve injuries and to leverage our existing distributor network to drive adoption of Remplir across these key institutions.

Importantly, Remplir has already demonstrated its value in conflict-related injuries in Ukraine, highlighting its suitability for the types of trauma commonly encountered within military healthcare systems.

Orthocell is well positioned to capitalise on this expanded access with its existing network of distributors and in-house sales and medical education teams, and will continue to pursue opportunities to increase utilisation of Remplir across key U.S. healthcare segments, including military and veteran care.


[1] As at 31 March, 2026

Release authorised by:
Paul Anderson
Orthocell Ltd CEO and MD

For more information, please contact:

General enquiries

 

Paul Anderson

Orthocell Limited

CEO and MD

P: +61 8 9360 2888

E: paul.anderson@orthocell.com 

Media enquiries

 

Haley Chartres

H^CK Director

 

P: +61 423 139 163

E:  haley@hck.digital 

Investor enquiries

 

Shaun Duffy

VECTOR Advisors

 

P: +61 404 094 384

E:  sduffy@vectoradvisors.au  

About Orthocell Limited 
ACN 118 897 135
Registered Office – Building 191 Murdoch University, 90 South Street, Murdoch WA 6150 Australia

Orthocell is a regenerative medicine company focused on regenerating mobility for patients by developing products for the repair of a variety of bone and soft tissue injuries. Orthocell’s portfolio of products include a platform of collagen medical devices which facilitate tissue reconstruction and healing in a variety of dental and orthopaedic reconstructive applications. Striate+™ was the first product approved for dental GBR applications, is cleared for use in the US, Australia, New Zealand, Singapore, UK, Europe, Canada and Brazil and is distributed globally by BioHorizons Implant Systems Inc. Remplir™, for peripheral nerve reconstruction, recently gained clearance for use in the US. The Company has appointed a network of specialist US distributors and recorded initial sales. The Company’s flagship nerve repair product is also approved in Australia, New Zealand and Singapore where it is distributed by Device Technologies Group. Other Remplir approvals include Thailand, Canada and Hong Kong. SmrtGraft™, for tendon repair, is available in Australia under Special Access Scheme or participation in a clinical trial. The Company’s other major products are autologous cell therapies which aim to regenerate damaged tendon and cartilage tissue.  Orthocell is accelerating the development of its tendon cell therapy in the US with technology transfer and FDA engagement to confirm the path to the US market and prepare for partnering discussions.    

For more information on Orthocell, please visit www.orthocell.com or follow us on Twitter @Orthocellltd and LinkedIn www.linkedin.com/company/orthocell-ltd

Forward Looking Statement

Any statements in this press release about future expectations, plans and prospects for the Company, the Company’s strategy, future operations, and other statements containing the words “anticipate,” “believe,” “estimate, “expect,” “intend,” “may,” “plan,” “predict,” “project,” “target, “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions, constitute forward-looking statements. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: the Company’s ability to successfully develop its product candidates and timely complete its planned clinical programs and the Company’s ability to obtain marketing approvals for is product candidates. In addition, the forward-looking statements included in this press release represent the Company’s views as of the date hereof. The Company anticipates that subsequent events and developments will cause the Company’s views to change. However, while the Company may elect to update these forward-looking statements at some point in the future, the Company specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company’s views as of any date subsequent to the date hereof.

First Ever APAC Pharmacists’ Guideline to Tackle Peripheral Neuropathy

Developed By APAC Pharmacist Experts

–  1 in 2 diabetics, and 1 in 10 adults suffer from Peripheral Neuropathy [1],[2]

–  Community pharmacists first and most accessible point of healthcare contact

–  New guidelines highlight emerging role of pharmacists in elevating the standard of care

SINGAPORE, April 16, 2026 /PRNewswire/ — Leading Asia-Pacific pharmacist experts, together with P&G Health, announced the region’s first guideline designed for community pharmacists to identify, assess, and manage patients with peripheral neuropathy (PN) in everyday pharmacy practice.


The “Empowering Community Pharmacists Expert Consensus Guidelines for the Effective Management of Peripheral Neuropathy with Neurotropic B Vitamins’ translates evidence into practical, culturally adaptable recommendations to standardize pharmacy-based screening, counselling, and stepwise management—narrowing the persistent gap of underdiagnosis and delayed treatment.

Dr. Yolanda R. Robles (Lead Author, Chairperson), Professor, College of Pharmacy, University of the Philippines; President of Federation of Asian Pharmaceutical Associations (FAPA) said, “PN is a widespread and often debilitating condition that has high prevalence amongst diabetic patients in APAC [3-7] – the Philippines (58%), Indonesia (58%), Malaysia (54%), Thailand (34%), Singapore (28%), and Australia (21%). With pharmacists being the most accessible health professional in many APAC countries, this consensus translates the best available evidence into simple steps for pharmacists to spot PN earlier, guide patients confidently, and partner physicians to improve long-term outcomes.”

Why this matters in Asia Pacific

Shraddha Vohra, Vice President, Personal Health Care Asia Pacific, P&G Health Singapore said, “Community pharmacies are often the first point of contact for people experiencing numbness, tingling, burning, or pins-and-needles in their hands and feet—symptoms commonly associated with PN. With up to 80% of PN cases in APAC estimated to remain undiagnosed, pharmacists are uniquely positioned to recognize symptoms early, guide patients to appropriate care, and help prevent progression. This guideline is tailored to the realities of pharmacy workflows, multilingual communities, and varied regulatory environments across APAC, and beyond, with tools that can be adapted locally to support rapid adoption.”

Reframing the role of pharmacists: from reactive management to proactive early screening and timely treatment

According to Contributing Author Dr. Apt. Lusy Noviani, Indonesian Pharmacist Association (IAI)“From behind the counter to the frontline, APAC pharmacists are moving from dispensing to early detection and proactive care. In countries like Indonesia, where doctor–to–population ratios are low, community pharmacists play a critical role in early screening and reducing delays in PN care.”

The new guidelines enable pharmacists to function as proactive care partners throughout the PN pathway by empowering them to:

  1. Spot at-risk patients early by applying a newly-created risk mnemonic (MEDIC)
  2. Differentiate nerve pain from muscle pain
  3. Use simple, validated screening questionnaires in-pharmacy (e.g., ACT, DN4, NPQ)[8]
  4. Initiate counselling, consider appropriate over-the-counter options including high-dose nerve nourishing B vitamins (B1, B6, B12) when suitable, and refer promptly when red flags are present
  5. Monitor and follow up to evaluate response, ensure safety and adjust individualized patient care plans

 

Spot PN early with MEDIC

“In busy pharmacy settings, simple tools matter. MEDIC is an easy-to-remember risk mnemonic that stands for M – Medication, E – Elderly, D – Diabetes, I – Infection, C – Chronic. Using MEDIC, pharmacists can flag patients at high risk of nerve damage early— without diagnosing, but by guiding next steps,” shared Dr. Navin Kumar Loganadan, Contributing Author & Head of Ambulatory Pharmacy & DMTAC (Diabetes Medication Therapy Adherence Clinic) Clinic, Malaysia.

“PN is often discovered late when nerve pain is severe. Our guideline empowers pharmacists to differentiate nerve from muscle pain early, apply validated screening tools, and initiate timely referrals. This shift from reaction to prevention can help patients restore nerve function and independence, added Ms. Grace Chew, Independent Pharmacist & Contributing Author, Singapore.

From screening to support: A clear care pathway

Dr. Kenny James P. Merin, Contributing Author & Lyceum of the Philippines University – Davao (LPU Davao) shared, “This guideline is about practical, everyday pharmacy. The steps are clear: identify risk, screen, counsel, consider therapeutic-dose B1, B6, and B12 where appropriate, and follow up consistently. With structured algorithms and checklists, pharmacists can standardize care without slowing workflow.”

It is common for patients to self-medicate for PN with vitamin B products, often using inappropriate dosage. This can lead to a lack of efficacy due to an insufficient dose or, conversely, overdose from certain B vitamins, which can worsen nerve-related symptoms. This is therefore an area where pharmacists can provide critical oversight toward improving patient outcomes.

“Therapeutic-dose neurotropic B vitamins have a role in comprehensive PN management for suitable patients with the right dose and duration. Our guideline emphasizes pharmacist vigilance—reassessing at 3–6 months, watching for red flags, and collaborating closely with physicians,” added Dr. Kitiyot Yotsombut, Contributing Author, Department of Pharmacy Practice, Chulalongkorn University, Thailand.

Access and implementation

The expert consensus guideline will be made available for APAC pharmacists via a newly launched resource portal, P&G Nerve Connect and expert-led webinars in the Philippines, Indonesia, Malaysia, Thailand, Singapore.

P&G Nerve Connect, a one-stop centre for pharmacists
P&G Nerve Connect, a one-stop centre for pharmacists

“Behavior change is never easy, our recent pharmacist survey in the Philippines showed that those completing five or more training sessions demonstrate significantly better knowledge on the right dose of B vitamins for PN. P&G Health’s Nerve Connect provides an always-on omnichannel education solution, transforming paper-based guidelines into engaging, everyday pharmacist practices,” added Dr. Yolanda R. Robles.

Shraddha Vohra from P&G shared, ” P&G Nerve Connect is a one-stop center for nerve health bringing together real-world patient case insights and practical tools to help pharmacists enhance patient interactions and strengthen everyday clinical decision-making. Pharmacists who face high patient flow, multiple tasks and limited capacity will have access to resources such as checklists and training videos. In addition, they will be encouraged to submit their patient cases to inspire their community and exchange learnings across APAC.”

To access the first APAC Pharmacists’ Guidelines for PN, visit https://mobile.swiperxapp.com/png-nerveconnect-ph/clinical-guideline/
To access P&G Nerve Connect, visit https://mobile.swiperxapp.com/png-nerveconnect-ph/

Notes to editors: The guideline is unbranded and intended for healthcare professional use. It complements, not replaces, physician diagnosis and care. Pharmacists should adhere to local regulations governing scope of practice, screening, and referral.

Media contact – MSL

Isha Meleth, MSL Singapore [Isha.meleth@mslgroup.com]

References

1. Malik, R.A. International Review of Neurobiology, Volume 127; 2016, 287-317.

2. Joel R.S, et. al., Current Medical Research and Opinion, 40(6), 977–987. https://doi.org/10.1080/03007995.2024.2352852

3. Diabetes: Australian Facts, Diabetes-Related Complications Available online (accessed on 19 September 2025).

4. Malik, R.A et. al.; J Diabetes Investig 2020, 11, 1097–1103, doi:10.1111/jdi.13269.

5. Malik, R.A. et al. Adv Ther 2017, 34, 1426–1437, doi:10.1007/s12325-017-0536-5.

6. Espiritu-Picar, R.B. et. al. Acta Med Philipp 2023, 57, 46–51, doi:10.47895/amp.vi0.4471.

7. Hu Hanquan, A. et. al.; Proceedings of Singapore Healthcare 2021, 30, 265–270, doi:10.1177/2010105820978993.

8. Gad, H.; et. al. Current Medical Research and Opinion 2025, 41, 93–104, doi:10.1080/03007995.2024.2443109.

 

Agoda Names Chiang Mai Asia’s Premier Culinary Destination

SINGAPORE, April 16, 2026 /PRNewswire/ — Digital travel platform Agoda has revealed that Chiang Mai has emerged as the top destination in Asia for culinary activities, based on activities booked on Agoda from January to March this year. For travelers eager to explore cooking classes, Bangkok, Hoi An, Ho Chi Minh City, and Hanoi round out the top five, underscoring the appeal of Thailand and Vietnam as culinary hubs in Asia.

It’s clear that food-forward activities are increasingly driving travel decisions. Agoda’s 2026 Travel Outlook Report highlights that culinary experiences have climbed into the top three motivators for Asian travelers, jumping from sixth place last year. Cooking classes, in particular, offer a unique way to immerse oneself in a destination’s culture, providing hands-on experiences that bring local traditions and flavors to life.

Here are the top five destinations for culinary enthusiasts, as identified by Agoda:

1. Chiang Mai, Thailand

Travelerscan engage in a hands-on culinary course in a local home and learn about traditional Thai ingredients through a guided tour of an organic farm. Before cooking, select fresh eggs or learn a unique coconut scraping technique. Travelers can discover authentic northern Thai specialties such as Khao Soi (coconut curry noodles) and Kaeng Hang Lei (ginger-tamarind pork curry).

2. Bangkok, Thailand

In the bustling district of Silom, travelers can participate in cooking classes led by expert instructors. These sessions include market visits to select fresh ingredients and lessons on preparing iconic dishes such as Tom Yum, Pad Thai, and various curries. Each day of the week features a different set menu, allowing participants to explore a wide range of Thai flavors and take-home recipes to recreate their favorite dishes.

3. Hoi An, Vietnam

Hoi An offers an exciting blend of cultural and culinary experiences for the food-lover and adventurer alike. At Cam Thanh coconut water village, travelers can enjoy a basket boat ride through the Bay Mau Nipa forest and discover traditional crab fishing methods. The experience provides a unique glimpse into the countryside and daily life of central Vietnam, with opportunities to master Vietnamese cuisine under the guidance of skilled local chefs.

4. Ho Chi Minh City, Vietnam

In the heart of the city, travelers can partake in a 3-course cooking class to prepare classic Vietnamese dishes, each menu carefully curated to highlight the unique flavors and cultural heritage of Vietnam. Those that prefer a specialty drink can opt for the egg coffee class, celebrating Vietnam’s renowned coffee culture. Travelers can also take a day trip to the Mekong Delta to explore local villages and sample regional specialties, including a workshop to learn how to make coconut candies.

5. Hanoi, Vietnam

Participants will prepare dishes like Pho bo (beef noodle soup), Bun cha (grilled pork with vermicelli), and Nem ran (fried spring rolls), enjoying their creations alongside classmates and sampling local rice wine. The experience includes a cookbook and certificate, allowing travelers to take home a piece of Hanoi’s culinary heritage.

Krishna Rathi, Associate Vice President at Agoda, shared, “Culinary experiences are a gateway to understanding a culture, and at Agoda, we are thrilled to connect travelers with these enriching opportunities. In Asia, Thailand and Vietnam stand out as culinary hubs, with rich flavors and an exciting selection of immersive experiences to choose from. Agoda makes it easy to book a wide range of activities alongside flights and accommodations for a seamless connected trip.” 

Travelers seeking unique experiences can browse over 300,000 activities, along with more than 6 million holiday properties and over 130,000 flight routes, all of which can be combined in the same booking. Discover the best deals on Agoda’s mobile app or visit Agoda.com for more.