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HIXXHOME Smart Birdfeeder and CoolFly App recognized as a House Digest Best of CES 2025

LAS VEGAS, Jan. 15, 2025 /PRNewswire/ — A new smart birdfeeder from HIXXHOME and its companion app from CoolFly have been recognized by Home Digest as a Best of CES 2025 for their innovative features that enhance backyard birding.

Participating in their first CES, HIXXHOME and CoolFly demonstrated the new products outdoors with real bird visitors during the iMpact Connect Smart Home Showcase event nearby the CES venues.

House Digest named the smart bird feeder and app combination as a “top-tier product” in the recent surge of smart bird feeders that are gaining popularity, and awarded it as one of their

The HIXXHOME Bird Feeder with camera features 2.5k HD video quality and a wide 150-degree lens for capturing video of the bird from all angles at the feeder. It is powered by a solar panel, has infrared night vision, and uses AI bird identification to provide real time alerts and what type of bird is at your feeder.  It even has a repellent button that sounds an alarm to scare away squirrels.

The CoolFly app is the world’s first backyard birding app and works as an extension of the HIXXHOME smart bird feeder that allows you to see pictures and videos from the feeder. CoolFly also enables you to share content with other users as part of a bird-watching community. Multiple people can also see what’s happening at one bird feeder through their own accounts, and can discuss what they see within the app.

A few features make CoolFly standout. It provides free AI-powered bird identification, removing unnecessary expenses for bird identification and making the joy of birding accessible to everyone. It also plugs its users into a vibrant global interactive birder community where birders can share photos and videos, like and comment on posts, and engage with other birders worldwide. Dedicated group chats unite users of the same smart bird feeder in a private space, allowing authorized members to conveniently share bird videos and other special moments. The app also integrates a rich and engaging bird knowledge database, covering characteristics, sounds, size, wingspan, weight, diet and more.

CoolFly CEO and Founder Ryan Zhu said during the CES 2025 iMpact Connect Smart Home Showcase, “At CoolFly, we’re not just building a smart birdwatching tool—we’re creating a global community where nature lovers can connect, share, and enjoy birding together. CoolFly is here to bring birdwatchers closer to nature and each other, no matter what device you use.”

The HIXX Bird Feeder with Camera is priced at $129.99 in a selection of colors, and the CoolFly app is free for 30 days, then $5.99 per month or $59.90 per year.

About CoolFly
CoolFly is a pioneering company dedicated to connecting people with nature and fostering connections among birders worldwide through thoughtful tech innovation. CoolFly aims to create a vibrant global community centered around the joys of backyard birding, encouraging sharing and interaction to make birding an enjoyable experience for all. Learn more at the CoolFly website here.

2025 Sunhak Peace Prize: Honoring Global Leaders in Peace innovation

SEOUL, South Korea, Jan. 15, 2025 /PRNewswire/ — The Sunhak Peace Prize Committee, chaired by José Manuel Barroso, former President of the European Commission, proudly announces the laureates to be honored at the 2025 Sunhak Peace Prize Award Ceremony that takes place on April 11, 2025: Patrick Awuah Jr.(Ghana), Hugh Evans(Australia), and Wanjira Mathai(Kenya).

Patrick Awuah (Founder of Ashesi University)

Patrick Awuah Jr., Founder and President of Ashesi University in Ghana, has transformed higher education in Africa. His pioneering efforts have established Ashesi University as a model for cultivating ethical leadership and innovation. With a 90% graduate employment rate and a student body comprising 50% women, Awuah has empowered a new generation of African leaders to address the continent’s most critical challenges.

Hugh Evans, Co-founder and CEO of Global Citizen, has mobilized a remarkable $43.6 billion to combat poverty and advance global development. Through his advocacy, more than 1.3 billion lives worldwide have been positively impacted, with improved access to healthcare, education, and other essential services. Evans has redefined global activism, bridging grassroots movements with systemic policy changes to tackle inequality on a global scale.

Wanjira Mathai, Regional Director for Africa at the World Resources Institute, is a leading force in environmental restoration and sustainable development. As a driving figure in the Green Belt Movement, she has spearheaded the planting of 51 million trees and leads the AFR100 Initiative, which seeks to restore 100 million hectares of degraded land across Africa by 2030. Mathai’s work integrates ecological restoration with economic empowerment, creating sustainable livelihoods and combating climate change.

In addition, the Sunhak Peace Prize Foundation’s prestigious Founder’s Award will be presented to H.E. Xanana Gusmão, a key leader in East Timor’s struggle for independence. As the nation’s first President and current Prime Minister, Gusmão has championed peace and international solidarity through initiatives such as the g7+, fostering collaboration among fragile states to overcome shared challenges.

The award ceremony will take place on April 11, 2025, at 3 PM KST in Seoul, Korea, in a hybrid format. Each laureate will receive $200,000, a medal, and a plaque.

For more information, please visit www.sunhakpeaceprize.org.

Hugh Evans (Founder of Global Citizen)

Xanana Gusmão (Prime Minister of Timor-Leste)

Wanjira Mathai (Managing Director, Africa and Global Partnerships, World Resources Institute)

BLUETTI Unveils New Energy Innovations and Brand Identity at CES 2025

LAS VEGAS, Jan. 15, 2025 /PRNewswire/ — BLUETTI, a trailblazer in clean energy technology, unveiled three new product series—Apex, Elite, and EnergyPro—during its Breaking the Excellence brand refinement event at CES 2025. The highlight included Apex 300 and EnergyPro 6K flagship energy storage systems, reaffirming BLUETTI’s pioneering role in clean energy innovation.

BLUETTI

“This year, we’re redefining our brand to solidify our role as a technology pioneer in clean energy,” said Illia Zahnitko, BLUETTI’s spokesman. “With the 3rd-generation product series, we aim to transform energy storage and lead the way toward a sustainable future.”

BLUETTI’s Product Era 3.0: Elite, Aplex, and EnergyPro series

BLUETTI has evolved from its early EB and AC series and entered a new product era with three new product lineups, including:

  • Elite Series: Compact and portable power stations with outputs under 3kW, tailored for outdoor adventures, light RV use, and short-term home backup.
  • Apex Series: Scalable off-grid power solutions delivering over 3kW power, ideal for off-grid living, commercial applications, and high-demand scenarios.
  • EnergyPro Series: Professional-grade energy storage systems designed for small businesses and large households, offering dependable, long-term backup solutions.

Flagship Products: Apex 300 and EnergyPro 6K

The event spotlighted two groundbreaking products:

  • BLUETTI Apex 300: A versatile off-grid solution supporting 120V and 240V loads. With an expandable capacity of up to 58kWh and a maximum output of 11.52kW, it provides personalized energy solutions for home backup, RV trips, and off-grid living. It boasts industry-leading energy efficiency and supports up to 30,720W solar input.
  • BLUETTI EnergyPro 6K: An affordable home energy system that seamlessly integrates with existing solar setups, standby generators, and EV power sources. The scalable battery system offers reliable energy storage solutions for whole-home backup and energy cost reduction.

Driving Innovation Through Technology

BLUETTI also introduced its advanced tech ecosystem, comprising BLUEPEAK, BLUELINK, BLUEGRID, and BLUELIFE, which underpin its future product development. By combining innovation with sustainability, BLUETTI continues to set benchmarks in clean energy storage solutions.

About BLUETTI

Founded in 2009, BLUETTI is committed to a sustainable future by providing green and independent energy storage solutions for every household. With a strong focus on innovation and customer needs, BLUETTI has gained the trust of 3.5 million customers across over 110 countries & regions. Through initiatives like the LAAF (Lighting An African Family) Program, BLUETTI aims to bring power to millions of off-grid African families.

Samsung Biologics presents business updates at 2025 J.P. Morgan Healthcare Conference

– The company to mark new phase of growth at Bio Campus II with the opening of Plant 5 in April

– Samsung Biologics to offer ADC services and invest in advanced development and manufacturing capabilities to better address clients’ needs

INCHEON, South Korea, Jan. 15, 2025 /PRNewswire/ — Samsung Biologics (KRX: 207940.KS), a global contract development and manufacturing organization (CDMO), today announced its latest business achievements and 2025 outlook at the 43rd J.P. Morgan Healthcare Conference, which was held in San Francisco between January 13-16.

During the main track presentation, Samsung Biologics’ CEO and President John Rim said, “Despite industry challenges, Samsung Biologics is well positioned to kick-start a new phase of growth in 2025 with the opening of Bio Campus II and launch of antibody-drug conjugate (ADC) services.” He added, “We’ll continue to invest in new modalities and technologies to better address client needs, maximizing satisfaction and ensuring the delivery of highest-quality products.”

Key business updates include:

ADC services: To address the increasing demand for ADC-based therapeutics, Samsung Biologics has commenced ADC services at its new dedicated facility. Building on the company’s expertise in large-scale antibody manufacturing and process engineering, Samsung Biologics’ service scope spans late stage discovery, development, and conjugation. Samsung Biologics recently expanded its collaboration with LigaChem Biosciences to support a series of their ADC programs at Samsung Biologics’ new dedicated ADC facility.

Opening of Japan office: To better support Samsung Biologics’ expanding global client base, the company announced plans to open a regional office in Tokyo this year. The local presence will boost Samsung Biologics ability to support and grow its increasing partnerships in Japan.

Expanded Drug Product (DP) services: As part of continued efforts to expand service offerings, Samsung Biologics is investing in pre-filled syringe (PFS) capabilities. The company’s fully automated PFS DP line will be CGMP ready by 2027.

Enhanced development capabilities: Samsung Biologics plans to better support global pharma and emerging biotech companies by investing in core development capabilities. The company is offering services incorporating new tech platforms, including S-HiConTM, S-TensifyTM, S-AfuCHOTM, and S-OptiChargeTM, that ensure higher productivity and quality of a molecule for successful and accelerated drug development.

Capacity expansion: Samsung Biologics will mark a new phase of growth with the opening of Bio Campus II this year. Plant 5, the first facility of the new site, will be operational in April this year and bring up the total capacity to 784,000 liters. The company is also considering the construction of a sixth plant to proactively respond to the rising demand for biologics, which will increase total production capacity to 964,000 liters upon board approval.

Digital transformation: As part of efforts to maximize operational efficiency and client satisfaction, Samsung Biologics will continue to invest in further building its integrated digital systems spanning quality, manufacturing, and operations. Incorporating artificial intelligence and digital twin technology, the company plans to provide clients with data-enabled solutions and insight to optimize project timelines without compromising quality.

About Samsung Biologics Co., Ltd.

Samsung Biologics (KRX: 207940.KS) is a fully integrated, end-to-end CDMO service provider, offering seamless development and manufacturing solutions from cell line development to final aseptic fill/finish as well as laboratory testing support for the biopharmaceutical products we manufacture. Our state-of-the-art facilities are CGMP compliant with bioreactors ranging from small to large scales to serve varying client needs. Maximizing operational efficiency and expanding our capabilities in response to growing biomanufacturing demand, Samsung Biologics offers a combined 604 kL total capacity at Bio Campus I. The company launched Bio Campus II with the construction of Plant 5, which will be operational in April 2025, adding 180 kL biomanufacturing capacity. Additionally, Samsung Biologics America enables the company to work in closer proximity to clients based in the U.S. and Europe. We continue to upgrade our capabilities to accommodate our clients by investing in an ADC facility, mRNA technologies, and additional aseptic filling capacity. As a sustainable CDMO partner of choice, we are committed to on-time, in-full delivery of the products we manufacture with our flexible manufacturing solutions, operational excellence, and proven expertise.

Samsung Biologics Contact
Claire Kim, Head of Global Marketing Communications
cair.kim@samsung.com

QNET’s BELITE 123: Your Trusted Partner in Sustainable Health and Weight Management

HONG KONG, Jan. 15, 2025 /PRNewswire/ — With the start of a new year, many of us set ambitious goals to improve our health and manage our weight. While resolutions often fade, QNET’s

Irfan Aziz from Kuwait is one of many who have experienced life-changing results with BELITE 123. “After years of struggling with my weight, BELITE 123 made all the difference. I initially lost 2 kg, which kept me motivated; now I’ve shed 12.4 kg in total! But it’s not just about the weight—my mental clarity, sleep quality, and overall emotional balance have improved significantly,” Irfan shares. “BELITE 123 takes the ‘T’ out of Can’t!

A Proven Formula for New Year Success

With its three-step system, BELITE 123 has become a cornerstone of health for individuals looking to stay fit and energized, even during festive seasons and indulgent celebrations. Each component is meticulously designed to support the body’s natural processes:

  • BELITE 01 (Green Tea & Kaffir Lime): Boosts metabolism and helps regulate blood pressure.
  • BELITE 02 (African Mango): Reduces appetite and supports cholesterol management, with studies showing a 27.3% reduction in LDL.
  • BELITE 03 (Peppermint & Cinnamon): Detoxifies, improves digestion, and promotes restful sleep.

This effective system allows users to embrace healthier habits without sacrificing enjoyment. Whether it’s savoring holiday treats or maintaining daily routines, BELITE 123 supports a balanced lifestyle year-round.

A Long-Term Commitment to Wellness

Trevor Kuna, QNET’s Chief Marketing Officer, underscores the importance of adopting a sustainable approach to health. “Weight management isn’t just a resolution; it’s a lifestyle. BELITE 123 is built to help people achieve their health goals by integrating seamlessly into daily life. It’s not about quick fixes but creating long-lasting habits that lead to better health and greater vitality.”

Kuna emphasizes that the secret to BELITE 123’s success lies in its holistic approach. “Our product doesn’t just target weight loss; it addresses overall well-being, which is key to maintaining a healthy and fulfilling life,” he adds.

Easy to Follow, Backed by Science

The BELITE 123 system is simple to incorporate into even the busiest lifestyles:

  1. BELITE 01: Drink after breakfast to jumpstart your metabolism.
  2. BELITE 02: Take before lunch to curb appetite and support fat burning.
  3. BELITE 03: Drink after dinner to cleanse and detoxify overnight.

With natural ingredients sourced from Asia, Africa, and Europe, BELITE 123 combines ancient wisdom with modern science to deliver sustainable results. Its global following is a testament to its effectiveness and the trust it has earned over the years.

Renew Your Commitment to Health This Year

As we step into 2025, BELITE 123 offers a trusted solution for anyone looking to take charge of their health. It’s more than just a product; it’s a partner on your journey toward a healthier, more balanced life. Let BELITE 123 help you turn your resolutions into reality—and sustain them throughout the year.

ABOUT QNET
QNET, a global lifestyle and wellness company, uses a direct selling business model to promote unique products that enable people to take charge of their health, well-being, and lifestyle.

Since 1998, QNET’s innovative products and e-commerce-driven business model have helped build a global community of satisfied customers and microentrepreneurs, who are driven by the mission of RYTHM – Raise Yourself To Help Mankind. Popular product brands offered by QNET include the Bernhard H. Mayer range of luxury watches and jewellery, HomePure range of home care products, the Amezcua wellness range, Physio Radiance personal care range, and QVI branded holiday packages.

QNET proudly exemplifies high industry standards and is a member of numerous Direct Selling Associations worldwide. Its active engagement in several global sports sponsorships including in its role as the official direct selling partner of the Manchester City Football Club (MCFC) and the Confederation of African Football (CAF), highlights the company’s commitment to excellence.

Discover a world of new possibilities with QNET by visiting www.qnet.net

French Hydrogen New Energy Partners with Dacheng (National) Trustworthy Auto Repair

Reduce Costs, Improve Efficiency

Promote Energy Conservation and Emission Reduction for Trucks

HONG KONG, Jan. 15, 2025 /PRNewswire/ — In late November last year, Hong Kong-listed company China International Development Holdings (00264.HK) announced that it signed the memorandum of understanding for the possible formation of a joint venture with its strategic partner, French-based Flex Fuel Energy Development Ltd (FFED), are going to form the JV Company as soon as practicable. The collaborate on the research and development, production and sales of the hydrogen injection cleaning system for motor vehicle’s engine, with an aim to address air pollution control for motor vehicles and non-road mobile sources in China, achieving energy-saving, emission reduction, cost reduction, efficiency improvement and contributing to the dual carbon goals of China.

Recently, Dacheng (National) Trustworthy Auto Repair Chain Co., Ltd. and Flex Fuel Energy Development (Shenzhen) Co., Ltd. have reached a strategic partnership for deeper integration. Together, they will provide high-tech, high-efficiency hydrogen engine maintenance equipment to truck drivers and transportation companies across the country, achieving cost reduction, efficiency improvement, energy conservation, and emission reduction benefits—a cooperation worth noting.

As a leading player in the truck repair industry, Dacheng Truck Repair (National) Chain adheres to the principles of “maintenance over repair” and “green repair.” It is a pioneer in China’s truck repair chain industry. Its core business includes technical training, talent supply, vehicle coordination, centralized procurement of spare parts, vehicle lifecycle maintenance services for major clients, and financial services. Additionally, Dacheng Truck Repair and Xinzongan Coordinated Insurance leverage nearly 1,500 chain repair shops nationwide and numerous strategic logistics fleet partnerships to provide internal insurance services for logistics fleets. These services reduce costs, improve efficiency, and increase accident repair volumes for repair shops. This dual approach not only lowers insurance participation costs for logistics fleets and truck drivers but also enhances safety assurance, offering nationwide rescue, joint guarantees, and unified services.

Flex Fuel Energy Development focuses on preventing pollution from motor vehicles and non-road mobile sources. By leveraging technological innovation, it plays a key role in supporting and leading efforts to protect blue skies. It contributes to achieving green, low-carbon, high-quality development while synergizing pollution reduction and carbon reduction. As a leader in “green repair” for the automotive industry, Flex Fuel Energy Development is committed to developing hydrogen-based energy-saving and emission-reduction technologies, helping the industry transition toward high-quality, sustainable, and low-carbon development.

The collaborate on the research and development, production and sales of the hydrogen injection cleaning system for motor vehicle’s engine, with an aim to address air pollution control for motor vehicles and non-road mobile sources in China, achieving energy-saving, emission reduction, cost reduction, efficiency improvement and contributing to the dual carbon goals of the China.

Using Flex Fuel’s hydrogen engine maintenance equipment not only effectively improves engine combustion efficiency but also employs advanced hydrogen cleaning technology for engines in a more environmentally friendly and efficient manner.

Dacheng Car Repair (Nationwide) Chain is the pioneer of China Car Repair Chain.

Flex Fuel Energy Development (Shenzhen) Co., Ltd. is the Asia-Pacific subsidiary of Flex Fuel Energy Development Ltd, a French technology company founded in 2008 and listed among the French Tech 120 Index. The company holds exclusive sales and production authorization for the Asia-Pacific region. Its hydrogen engine maintenance equipment has received official safety certifications from entities such as the French National Railway, the Marine Agency, and the Ministry of Environment. Currently, the group engages in hydrogen research and production equipment, offering comprehensive energy solutions tailored to customer needs. These solutions reduce costs, align with global trends, utilize renewable energy, directly reduce emissions, save energy, and meet commercial ESG standards.

Backed by Real-World Test Data

According to real-world test data, using Flex Fuel’s hydrogen engine maintenance equipment not only effectively improves engine combustion efficiency but also employs advanced hydrogen cleaning technology for engines in a more environmentally friendly and efficient manner. This significantly reduces the maintenance time required by technicians and lowers risks during repairs. For truck drivers, the benefits include improved combustion efficiency, enhanced horsepower, reduced fuel consumption, lower engine noise, reduced idling vibration, lighter throttle response, faster acceleration, elimination of exhaust odor, complete combustion in the engine chamber, and restored vehicle performance to near-new conditions—all in one go.

Advantages for Flex Fuel Energy Development (Shenzhen)

Through its strategic partnership with Dacheng (National) Trustworthy Auto Repair Chain, Flex Fuel Energy Development (Shenzhen) can rely on Dacheng’s extensive network of nearly 1,500 repair chain outlets nationwide and the resources of Xinzongan Coordinated Insurance, which covers nearly 200,000 insured vehicle owners. The hydrogen maintenance project will serve a wide range of truck drivers and logistics fleets. By offering regular maintenance services, large fleet maintenance plans, and value-added insurance services, the partnership between Dacheng and Flex Fuel not only helps truck drivers save costs but also empowers the Dacheng system with the principles of “maintenance over repair” and “green repair,” creating a better future together.

About French Hydrogen New Energy (Shenzhen) Co., Ltd

FFED’s engine hydrogen maintenance equipment has been officially certified by the French Railways Agency, the Oceanic Agency, the Ministry of Environmental Protection and other official safety certifications.

French Hydrogen New Energy (Shenzhen) Co., Ltd. is an Asia-Pacific subsidiary of French French Hydrogen New Energy Co., Ltd. (founded in 2008, one of the French technology 120 index companies). It has the exclusive sales and production authorisation in the Asia-Pacific region. The engine hydrogen maintenance equipment has been officially certified by the French Railways Agency, the Oceanic Agency, the Ministry of Environmental Protection and other official safety certifications. At present, the group is engaged in hydrogen research and development and production equipment, providing a full range of energy solutions, applying its equipment and the hydrogen produced according to customer needs, so as to reduce costs, meet the world trend, apply renewable energy, directly reduce emissions and save energy, and meet the requirements of commercial ESG.

About Dacheng Car Repair (Nationwide) Chain

Dacheng Car Repair (Nationwide) Chain is focusses on technical training, talent transfer, vehicle coordination, accessories collection, full life cycle maintenance services for large customer vehicles, and financial business.

Dacheng Car Repair (Nationwide) Chain is the pioneer of China Car Repair Chain. Its business focuses on technical training, talent transfer, vehicle coordination, accessories collection, full life cycle maintenance services for large customer vehicles, and financial business.

Dacheng Car Repair and Xinzhong’an coordinated insurance, owning nearly 1,500 chain repair shops and many strategic cooperation logistics fleets across the country.

Dacheng Car Repair and Xinzhong’an coordinated insurance, taking the opportunity of nearly 1,500 chain repair shops and many strategic cooperation logistics fleets across the country, not only to carry out internal protection for logistics fleets, reduce costs and increase efficiency, but also increase the maintenance volume of accident vehicles for repair shops, that is, reduce the participation fee for large logistics fleets and car friends, and obtain safety and security. . National rescue, joint insurance and continuous service.

Two Agilent Factories Among 13 to Join World Economic Forum Lighthouse Network

Recognition brings the company a total of four Lighthouse designations as global advanced factory for its breakthroughs in scaling Fourth Industrial Revolution

SANTA CLARA, Calif., Jan. 15, 2025 /PRNewswire/ — Agilent Technologies Inc. (NYSE: A) today announced the World Economic Forum has named two of Agilent’s smart factories in Asia as a Global Lighthouse Network, a community of 189 global leaders leading the way in the Fourth Industrial Revolution (4IR) in advanced manufacturing.

Agilent’s new Lighthouse designation as global advanced factory located at Bayan Lepas in Penang, Malaysia

Agilent sites in Shanghai, China, and Penang, Malaysia, are two of 13 factories across the world that have just been added to the latest cohort of Lighthouses.

This recognition marks Agilent’s third and fourth Lighthouses for its breakthroughs in scaling AI, 3D printing, robotics, big-data analytics, and industrial internet of things (IIoT). Since 2022, two of Agilent’s manufacturing sites – Singapore and Waldbronn, Germany – have earned this prestigious distinction. The company remains the sole analytical and clinical laboratory technology company worldwide to be recognized by the Forum.

“This important milestone showcases Agilent’s leadership in building factories of the future by integrating advanced digital technologies across our end-to-end operations,” said Agilent CEO Padraig McDonnell. “Our factories of the future not only elevate our customers’ experiences and exceed their expectations, but they also continuously develop our future workforce.”

Agilent’s Shanghai factory serves as a global strategic manufacturing hub, integrating R&D, quality-assurance, supply-chain and logistics-management capabilities. To enhance the production of highly customized gas chromatography, it deploys smart manufacturing with AI-assisted instrument design, using cutting-edge indexed repository to optimize precision, efficiency, and innovation.

As a result, the site has improved productivity by 56%, lead time by 31%, and customer satisfaction on delivery exceeding 96%. Today, China has become the single largest market for Agilent outside of the U.S. and has been an important part of the company’s growth strategy.

Agilent Penang deploys game-changing AI in 3D-printing to automate material configuration, optimize printing of highly customized components, and minimize waste. By integrating AI, machine learning, and advanced analytics into additive manufacturing, the factory reshaped a capacity-saturated site into a digital operation with real-time monitoring and predictive insights for smarter, more agile production capabilities.

Its integrated digital platform has improved productivity by 40%, manufacturing cost by 32% and delivery lead time by 48%. As one of Agilent’s global strategic facilities, the Penang factory hosts a state-of-the-art Global Instrument Design Center and a Biochemical Safety and Reliability Lab.

“Empowering the frontline and fostering inclusive digital cultures is at the heart of success for Lighthouses,” said Fernando Perez, Senior Partner and Head of Operations Innovations, McKinsey & Company. “These pioneering sites are building resilient, future-ready workforces and demonstrate that investing in people is as crucial as investing in technology. It is the powerful combination of both that drives meaningful change that extends beyond factory walls to make positive impact across production ecosystems.”

Tapping into 4IR technologies, Agilent successfully built resilient value chain ecosystems capable of quick response to evolving market demands. These advancements provide scientists with faster access to the instruments they need, accelerating research discoveries. With its long-standing values of innovation, Agilent continues pushing its smart factories around the world to bring great science to life and serve as a beacon to other manufacturers globally.

About the Global Lighthouse Network

Launched in 2018, the Global Lighthouse Network brings together and celebrates the success of the world’s leading industrial sites which achieved exceptional performance in productivity, supply chain resilience, customer centricity, sustainability and talent. This global community of influential innovators, deploying over 1,000 solutions in multiple industries, includes 189 sites, 25 of which are Sustainability Lighthouses. The network now spans over 30 countries and 35 sectors. The initiative was co-founded by the World Economic Forum and Mckinsey & Company. Learn more at WEForum.org.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in analytical and clinical laboratory technologies, delivering insights and innovation that help our customers bring great science to life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers’ most challenging questions. The company generated revenue of $6.51 billion in fiscal year 2024 and employs approximately 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.

For Information

Media Relations, South Asia Pacific & Korea
Grace Thong
Agilent Technologies
+65 9688 2152
grace.thong@agilent.com

Axcynsis Therapeutics Receives FDA Clearance for IND Application of AT03-65, a Differentiated CLDN6-Targeting ADC, Powered by AxcynDOT™ Technology

AT03-65 is the first program utilizing AxcynDOT™, a proprietary payload with a differentiated mechanism of action, to enter clinical development

SINGAPORE, Jan. 15, 2025 /PRNewswire/ — Axcynsis Therapeutics Pte Ltd (“Axcynsis”), a privately held biopharmaceutical company specialized in delivering Antibody Drug Conjugates (ADCs) with breakthrough potential, proudly announces the clearance of its Investigational New Drug application (IND) by the United States Food and Drug Administration (FDA) of AT03-65 for the treatment of patients with CLDN-6 positive solid tumors. Axcynsis is planning to initiate a Phase 1 multicentre clinical trial in the United States in 1Q 2025.

AT03-65 is a differentiated ADC that selectively binds to CLDN6 with strong affinity. It is enabled by AxcynDOT™, a proprietary payload that incorporates a derivative of an approved oncology therapeutics with unique mechanism of action and broad anti-tumor activity, and coupled with a cleavable and hydrophilic proprietary linker. CLDN6 is overexpressed in many cancers including lung, ovarian, endometrial, uterine, testicular, and gastric cancers while exhibiting minimal expression in normal tissues.  AT03-65 is designed to deliver targeted therapy to improve patient outcomes with advanced or metastatic CLDN6-positive cancers.

“This is a transformational event for Axcynsis and a significant milestone for our proprietary ADC platform using AxcynDOT™,” said Dr. Zou Bin, CEO of Axcynsis. “We are pleased that FDA has cleared AT03-65 which leverages our AxcynDOT™ technology for this first-in-human study.  We are very excited with the potential of offering a transformative therapeutic option for patients with CLDN6-positive tumors as well as advancing our pipeline with  differentiated  and effective ADCs using AxcynDOT™ to improve the lives of cancer patients worldwide”.

The upcoming Phase 1 multicentre clinical trial in the United States will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of AT03-65 in patients with advanced CLDN6-positive solid tumors.

About AT03-65

AT03-65 is a recombinant anti-CLDN6 monoclonal antibody conjugated to AxcynDOT™, a proprietary payload developed by Axcynsis with a differentiated mechanism of action and broad anti-cancer activities.  AT03-65 is designed to target advanced, recurrent, or metastatic CLDN6+ solid tumors in patients who have progressed on or after standard systemic treatment or for whom no standard therapies are available.

The antibody of AT03-65 is rationally engineered for high affinity and specificity to CLDN6. Upon binding to CLDN6-expressing tumor cells, the ADC is internalized into lysosomes, where it releases its payload to inhibit tumor growth effectively. Preclinical studies demonstrate that AT03-65 not only directly kill CLDN6-positive tumor cells but also exhibits bystander killing effect, targeting neighboring CLDN6-negative tumor cells to enhance its anti-tumor efficacy. AT03-65 has demonstrated promising anti-tumor activities in multiple tumor mouse models and a favorable safety profile in non-human primates.

About AxcynDOT™

This is a proprietary payload developed by Axcynsis. It is a derivative of trabectedin, an approved chemotherapy in the United States, Europe and selected Asian countries, with a unique mechanism of action that is differentiated from other DNA alkylating payloads. AxcynDOT™ is optimized with enhanced potency and improved safety profile compared to trabectedin.

About Axcynsis Therapeutics

Axcynsis Therapeutics is a pioneering biotechnology company headquartered in Singapore with operations in the United States. The company has developed AxcynDOT™ , a proprietary linker payload platform to advance a pipeline of differentiated ADC candidates aimed at addressing key unmet medical needs. The company is committed to advance effective and targeted oncology therapeutics with breakthrough potential to improve the lives of cancer patients worldwide.

For more information, please visit Axcynsis Therapeutics’ official website
https://axcynsis.com/

Contact Information

Axcynsis Therapeutics Pte Ltd
41 Science Park Road
#04-18, The Gemini
Singapore 117610
Email: contactus@axcynsis.com