– Expected to enroll approximately 4,600 participants with obesity or overweight across two pivotal trials (AURORA-1 and AURORA-2) in the U.S., Europe, and Canada. 

– Global Phase III clinical program to investigate efficacy and safety of three maintenance doses (20 mg, 40 mg, and 60 mg) over 72 weeks in participants with obesity or overweight without type 2 diabetes (AURORA-1) and with type 2 diabetes (AURORA-2).

– Topline data from the AURORA Phase III clinical program are expected in the third quarter of 2028, with a U.S. Food and Drug Administration (FDA) New Drug Application (NDA) submission expected by the end of 2028 and European Medicines Agency (EMA) Marketing Authorisation Application (MAA) submission expected in early 2029.

– ASC30 has the potential to become the second oral small molecule GLP-1 receptor agonist available in the U.S. and Europe, if approved.

HONG KONG, Aug. 30, 2026 /PRNewswire/ — Ascletis Pharma Inc. (HKEX: 1672, “Ascletis”) announced that the first participant has been dosed in a global Phase III clinical program of ASC30 for chronic weight management. ASC30 is an investigational, proprietary once-daily oral small molecule glucagon-like peptide-1 receptor (GLP-1R) agonist being developed for chronic weight management and diabetes.

The global Phase III clinical program consists of two pivotal, multicenter, randomized, double-blind, placebo-controlled Phase III trials, AURORA-1 (NCT07743463) and AURORA-2 (NCT07743450), evaluating the long-term efficacy, safety, and tolerability of ASC30 once-daily oral tablets in approximately 4,600 participants across clinical sites in the U.S., Europe, and Canada.

“Obesity is a complex, chronic disease associated with over 200 comorbidities and represents an immense global public health burden. While injectable incretin therapies have transformed obesity care, there remains substantial unmet need for an oral small molecule that is effective, well-tolerated, and convenient enough to expand patient access and support long-term adherence.” said Jinzi Jason Wu, Ph.D., Founder, Chairman and CEO of Ascletis, “Dosing the first participant in our AURORA global Phase III clinical program marks a transformative milestone for Ascletis. ASC30 enters this pivotal stage backed by a competitive Phase II weight loss profile, favorable gastrointestinal tolerability, and no observed hepatic safety signals. We believe this foundation supports ASC30’s potential as a category-leading oral therapy, with the goal of bringing patients a once-daily oral GLP-1 option approved globally.”

Ascletis expects to report topline data from the AURORA Phase III clinical program in the third quarter of 2028. The Company expects to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) by the end of 2028 and a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) in early 2029. Ascletis maintains a strong balance sheet with sufficient cash on hand to support operations into 2029, fully funding the program beyond the planned U.S. and European regulatory submissions.

Ascletis has one of the most comprehensive and leading oral small molecule portfolios for obesity. In addition to the AURORA global Phase III monotherapy program, Ascletis is also developing the first tirzepatide-like oral small molecule dual agonist fixed-dose combination GLP-1/GIP (ASC30_48FDC), the first tirzepatide/eloralintide-like oral small molecule triple agonist fixed-dose combination GLP-1/GIP/amylin (ASC30_48_39FDC), and a fixed-dose combination of our small molecule oral GLP-1 and oral amylin (ASC30_39FDC).

About the ASC30 Global Phase III Clinical Program

The ASC30 global Phase III clinical program consists of two pivotal, multicenter, randomized, double-blind, placebo-controlled Phase III trials, AURORA-1 (NCT07743463) and AURORA-2 (NCT07743450), which are designed to evaluate the long-term efficacy, safety, and tolerability of once-daily oral ASC30 compared to placebo in approximately 4,600 adults living with obesity or overweight, with treatment duration of 72 weeks and across both pivotal trials:

AURORA-1 (NCT07743463): A pivotal trial evaluating efficacy and safety of once-daily oral ASC30 in participants with obesity (body mass index (BMI) ≥ 30 kg/m²) or overweight (BMI ≥ 27 kg/m² with at least one weight-related comorbidity), excluding type 2 diabetes. Participants are randomized to one of three maintenance doses of ASC30 (20 mg, 40 mg, or 60 mg) or placebo. The primary endpoint is the percentage change in body weight from baseline to Week 72.

AURORA-2 (NCT07743450): A pivotal trial evaluating efficacy and safety of once-daily oral ASC30 in participants with obesity or overweight (BMI ≥ 27 kg/m²) and with type 2 diabetes. Participants are randomized to one of three maintenance doses of ASC30 (20 mg, 40 mg, or 60 mg), or placebo. The primary endpoint is the percentage change in body weight from baseline to Week 72.

About ASC30

ASC30 was discovered and developed in-house by Ascletis as an investigational oral small molecule GLP-1R fully biased agonist. It serves as the primary pillar of Ascletis’ comprehensive, industry-leading oral small molecule obesity portfolio, which also includes fixed-dose combinations spanning GLP-1, GIP, and amylin targets (such as ASC30_48FDC, ASC30_48_39FDC and ASC30_39FDC) to provide convenient, one-pill, once-daily treatment options for people living with obesity and other metabolic diseases.

About Ascletis Pharma Inc.

Ascletis Pharma Inc. is a fully integrated biotechnology company focused on the development and commercialization of potentially best-in-class and first-in-class therapeutics to treat metabolic diseases. Utilizing its proprietary Artificial Intelligence-assisted Structure-Based Drug Discovery (AISBDD) and Ultra-Long-Acting Platform (ULAP) technologies as well as Peptide Oral Transport ENhancement Technology (POTENT), Ascletis has developed multiple drug candidates in-house, including both small molecules and peptides, such as its lead program, ASC30, a once-daily oral small molecule GLP-1R agonist for chronic weight management and diabetes; ASC30_48FDC, a once-daily oral small molecule dual agonist, a fixed dose combination of ASC30 (GLP-1R agonist) and ASC48 (GIPR agonist), ASC30_48_39FDC, a once-daily oral small molecule triple agonist, a fixed dose combination of ASC30 (GLP-1R agonist), ASC48 (GIPR agonist) and ASC39 (amylin receptor agonist (SARA)), ASC39, an eloralintide-like potent selective amylin receptor agonist (SARA) once-daily oral small molecule, ASC30_39FDC, a once-daily oral small molecule dual agonist, a fixed dose combination of ASC30 (GLP-1R agonist) and ASC39 (amylin receptor agonist (SARA)), ASC36, an amylin peptide, designed to be administered once monthly to once quarterly subcutaneously and once daily orally, ASC35, a once-monthly subcutaneously administered GLP-1R/GIPR dual peptide agonist, ASC36_35FDC, a once-monthly subcutaneous triple peptide agonist, a fixed combination of ASC36 (amylin receptor agonist) and ASC35 (GLP-1R/GIPR agonist), ASC37, a GLP-1R/GIPR/GCGR triple peptide agonist, designed to be administered once monthly subcutaneously and once daily orally, and ASC36_37FDC, a once-monthly subcutaneous quadruple peptide agonist, a fixed dose combination of ASC36 (amylin receptor agonist) and ASC37 (GLP-1R/GIPR/GCGR agonist), for chronic weight management. Ascletis is listed on the Hong Kong Stock Exchange (1672.HK).

For more information, please visit www.ascletis.com. 

Contact:

Peter Vozzo
ICR Healthcare
443-231-0505 (U.S.)
Peter.vozzo@icrhealthcare.com 

Ascletis Pharma Inc. PR and IR Teams
+86-181-0650-9129 (China)
pr@ascletis.com
ir@ascletis.com

NEW YORK, Aug. 30, 2026 /PRNewswire/ — Gaming peripheral brand ATTACK SHARK has announced the launch of the R86 HE Carbon Fiber Magnetic Switch Gaming Keyboard, a flagship model designed to elevate expectations for high-end competitive gaming keyboards. Scheduled for release on 7 September 2026, the R86 HE is among the few magnetic switch keyboards to combine a 75% layout with a carbon fiber composite top case, bringing together advanced materials, precision magnetic switch technology, refined acoustics, and extensive customization.

As magnetic switch technology becomes a key driver of innovation in the gaming peripheral market, user expectations have expanded beyond speed alone. Today’s players are increasingly seeking a combination of performance, build quality, sound, and personalization. The R86 HE answers those demands with a carbon fiber composite structure, tournament-grade magnetic switch performance, and a Hi-Fi-inspired acoustic design, creating a new-generation 82-key gaming keyboard that balances competitive capability with everyday usability.

Carbon Fiber Construction Meets Practical 75% Layout

The R86 HE features a compact 82-key, 75% layout that retains dedicated arrow keys and essential functions while saving valuable desk space. Designed for both competitive gaming and everyday productivity, it delivers functionality without the bulk of larger keyboards.

Its premium design combines a carbon fiber composite top case with anodized CNC aluminum alloy side accents, creating a distinctive flagship look inspired by high-performance materials. The forged carbon texture offers exceptional rigidity and durability, while carbon fiber composite keycaps provide a crisp, consistent typing feel suited to fast-paced gaming.

0.005mm Rapid Trigger Accuracy for Competitive Play

In competitive FPS titles, a perfectly timed counter-strafe can be the difference between landing a decisive shot and missing a critical opportunity. The R86 HE’s 0.005mm Rapid Trigger Accuracy enables extremely precise key reset and actuation control, helping players transition seamlessly between movement and aiming. Combined with a custom esports chipset featuring 256K scanning and an 8000Hz polling rate, the keyboard achieves response times as low as 0.08ms, delivering the speed and consistency needed for fast-paced competitive gameplay.

Hi-Fi Acoustics for a Refined Typing Experience

Magnetic switch keyboards are often defined by speed, but the R86 HE goes beyond raw performance. A five-layer sound-dampening structure, comprising PE foam, IXPE switch pads, PET acoustic film, switch socket foam, and bottom silicone padding, helps reduce unwanted resonance for a cleaner, more refined typing sound. A premium fiberglass positioning plate enhances stability and feedback, while custom Huano Glass Jade magnetic switches balance ultra-fast responsiveness with a crisp, satisfying acoustic profile.

Built for Personalization

The R86 HE supports multiple high-performance magnetic switches and independent curve tuning, enabling personalized actuation settings for different gaming styles.

Full-key RGB lighting and dual-side dynamic light strips add visual impact, while web-based and PC software provide convenient access to key mapping, switch adjustments, and other customization options.

More than a high-performance gaming keyboard, the ATTACK SHARK R86 HE represents a fusion of advanced materials, acoustic engineering, and competitive-grade technology. By combining a unique 75% layout, carbon fiber flagship design, Hi-Fi acoustics, and 0.005mm Rapid Trigger Accuracy, it introduces a distinctive new option for users seeking both elite performance and premium craftsmanship.

For more information, visit https://attackshark.com/ or connect with the brand on social media and Discord.

To place an order, visit ATTACK SHARK Amazon Store for the US, UK, Europe, Australia, Mexico, Saudi Arabia and Japan.

NEW YORK, Aug. 30, 2026 /PRNewswire/ — Yaber announced the launch of the Yaber HP20 Cordless Vacuum Cleaner, redefining what budget–conscious consumers can expect, featuring TÜV–certified true 180AW suction, SGS–verified H13 HEPA filtration, and SenseClean AI that automatically adjusts power based on real-time debris detection.

TÜV–tested 180AW Suction Powerful Performance from Floor to Carpet

Compared to other low-aw vacuums, The HP20 delivers genuine TÜV–tested 180AW suction – a rarity in this price bracket. Its stiff–bristle roller brush effectively loosens embedded dirt from carpets and floors, while the powerful airflow lifts even stubborn debris, leaving surfaces spotless. Unlike ordinary vacuums, the HP20’s cyclone technology ensures consistent, fade–free performance from start to finish – so you never have to worry about weakening pickup halfway through cleaning.

SGS-certified H13 HEPA Filtration for Healthier Homes

Beyond visible dirt, the HP20 features a sealed 5–stage filtration system with H13 HEPA media, certified by SGS to capture 99.97% of microscopic particles, including fine dust, pollen, and pet dander under lab conditions. An anti–backflow design prevents contaminants from escaping back into the air – making it a top choice for families with children, pets, or allergy–sensitive members.

Auto-Suction Based on Dust Level by SenseClean AI Technology

No more manual mode switching. Equipped with Yaber’s SenseClean AI technology, the HP20 scans the floor thousands of times per second to detect dust levels in real time. It then automatically adjusts suction power – high for heavy messes, low for light dust – optimizing cleaning efficiency while maximizing battery life, so you clean smarter, not harder.

Visible Cleaning with Green LED Light and Versatile Attachments

To help users clean areas often overlooked, the HP20 incorporates a green LED dust detection light, revealing hidden dust, pet hair, and fine particles that ordinary lighting may miss.

Combined with an adjustable extension tube and multiple cleaning accessories, the HP20 easily converts into a handheld cleaner for stairs, furniture, sofas, car interiors, corners, baseboards, and other hard-to-reach spaces.

Pricing and Availability

The Yaber HP20 is now live on Amazon’s official Yaber store：https://www.amazon.com/gp/product/B0H2LWWYCX?maas=maas_adg_2F3844CE879126CA012EB35527CF1C50_afap_abs&ref_=aa_maas&tag=maas&th=1. For a limited time, apply code HP20PANPR at checkout to enjoy the exclusive launch price of $139.99. Don’t miss this opportunity to experience premium cleaning performance at an exceptional value.

HONG KONG, Aug. 30, 2026 /PRNewswire/ — While many students are still making their final preparations for the new school year, more than 350 student members of the Hong Kong Academy for Gifted Education (HKAGE, or the Academy) have already embarked on a distinctive start to their learning year. The Academy held three sessions of “Programme Showcase Day 2026” on 28 and 29 August, offering a diverse range of programme experiences that allowed student members to explore the Academy’s various gifted education courses for the coming year – covering areas such as artificial intelligence (AI), astronomy, environmental science, forensic science, art, and creative writing – thereby embarking on a new year of gifted learning.

Several top education leaders were invited to serve as officiating guests, including Dr LAM Tat Ho Lander, Chief Curriculum Development Officer (Gifted Education) of the Education Bureau; Prof WOO Kam Tim, Chairperson of the Talent Development Committee; and Principal WAN Shuk Fan Suki, Chairperson of the School and Student Services Committee. Drawing on their own rich learning and teaching experiences, they encouraged student members to discover their personal interests and potential, and to actively embrace the learning challenges ahead.

Diverse Programmes Inspire Members to Explore Their Interests

To enable students to explore different learning domains before the start of the new school year, seven themed interactive booths were set up for the Programme Showcase Day. Student members explored different classrooms at the Academy, engaging in hands-on interactive learning activities in a lively atmosphere:

• “Young Astronomers: Discover the Night Sky!“ – themed around astronomy and stargazing, participants were guided in using telescopes, star charts, and smart telescopes to learn about constellations, celestial motion, and the movements of the Moon and planets, sparking their curiosity about astronomy;

• “AI Arms in Action: Innovation for Social Good“ – showcased student members’ designs and creations from AI programmes, where participants could input commands on the spot to control robotic arms to identify and move objects, experiencing first-hand the application of AI technology. Senior students shared with their peers how the programmes integrate knowledge from AI, engineering, biomechanics, and product design, as well as their visits to elderly centres, explaining how they use creativity, knowledge, and technology to design innovative solutions for seniors and other people in need, improving quality of life through technology;

• Other booths included “Inclusive Storybook Corner“ – related to art and creative expression, where participants experienced using picture books and experiential games to promote the concept of inclusion in the community; “Forensic Science in Fiber Analysis“ – learning to explore forensic science knowledge through experiments, inquiry, and hands-on activities; “Environmental Science: Guardians of Our Urban Wildlife“ – an environmental science programme exploring Hong Kong’s forest history, seed dispersal mechanisms, and field studies on native tree planting; and “Maker Workshop“ – an innovation and technology programme covering the entire process from design and fabrication to the use of various tools.

At the opening ceremony, Dr LAM Tat Ho Lander, Chief Curriculum Development Officer (Gifted Education) of the Education Bureau; Prof WOO Kam Tim, Chairperson of the Talent Development Committee; and Principal WAN Shuk Fan Suki, Chairperson of the School and Student Services, each delivered a speech encouraging students to seize learning opportunities, expand their knowledge, enhance their capabilities, and unleash their creativity, so as to become future talents who possess both moral integrity and a sense of social responsibility.

The three guests pointed out that in an era of rapid AI development and rapid technological advancement, students should not only build a solid knowledge foundation, but also cultivate innovative thinking, critical thinking, and problem-solving skills. They should learn to make good use of technology and integrate knowledge across disciplines, so as to play to their strengths and contribute to the community in the future development of society and the global community.

Mr WONG Chung Po, Acting Executive Director of the HKAGE, said that through the Programme Showcase Day, the Academy hopes to offer student members a first-hand experience of the unique appeal of its gifted education programmes. By providing learning opportunities beyond the regular school curriculum, the Academy aims to ignite the passion for learning among gifted students. Through the provision of learning platform for student members, the Academy assists them in discovering their potential and enables them to plan ahead to enrol in their preferred gifted programmes at the earliest opportunity.

About the HKAGE
Established in 2008 and subvented by the Education Bureau, the HKAGE offers gifted education services actively to local primary and secondary school students to unleash their potential. It also provides gifted education-related information and support for teachers, parents, and other relevant stakeholders.

SINGAPORE, Aug. 30, 2026 /PRNewswire/ — AIMX Singapore 2026 has successfully concluded at Sands Expo & Convention Centre. Mr Tan Kiat How, Senior Minister of State, Ministry of Digital Development and Information, visited Runjian Co., Ltd.’s booth. As an official Platinum Partner of the event, Runjian focused firmly on Token overseas expansion, showcasing its Token-as-a-Service ecosystem layout across the ASEAN region under the theme “Token as a Service: Powering a Smarter ASEAN”.

At the exhibition, Runjian displayed a full lineup of innovative technological solutions covering multiple industry scenarios, including Wuxiang Cloud Valley Token Factory, Apollo 11 CEL enterprise platform, Lawer — ASEAN Legal AI Agent, Hanmate — Online Chinese Learning Platform, and iRun Renewable Energy Platform. The diversified product matrix fully demonstrates Runjian’s robust technical strength and practical application capabilities in core fields such as computing power service, green energy management, intelligent education, enterprise intelligent transformation and government digital governance. The innovative Token-driven technology system attracted extensive attention from global industry clients, developers and ecological partners, who conducted in-depth exchanges on ASEAN localized digital cooperation.

During the summit, Runjian delivered two influential keynote speeches at the main forum to share its overseas development layout. Athena Zhao, Vice President of Runjian Co. Ltd, elaborated on the innovative value of the Token-as-a-Service (TaaS) model in realizing inclusive and on-demand computing power services, helping Southeast Asian enterprises achieve efficient and cost-effective large-scale AI deployment. Meanwhile, Jake Yin, Vice President of the AI Business Group at Runjian Co. Ltd, shared the ontology-native advantages of the Apollo 11 platform, explaining how to help enterprises eliminate fragmented AI application pain points and build independent, controllable and continuously evolving proprietary intelligent systems.

Leveraging the high-end international platform of AIMX Singapore, Runjian actively connects global industrial resources to accelerate cross-border computing power circulation and Token overseas layout. Adhering to its unique regional development strategy, the company has set up overseas branches in Jakarta (Indonesia), Kuala Lumpur (Malaysia) and Thailand, with business coverage spanning all major ASEAN countries. Empowered by its solid local operational foundation, Runjian continues to deepen localized technological innovation and ecological cooperation across the ASEAN market. Moving forward, Runjian will join hands with global partners to build an open and win-win regional AI ecosystem, continuously empowering the high-quality development of the China-ASEAN digital economy.

CONTACT:
Annie Wang
marketing@runjian.com
18535579700

KOH SAMUI, Thailand, Aug. 29, 2026 /PRNewswire/ — A groundbreaking ceremony for the new Club Med Koh Samui resort was held on Tuesday, 25 August 2026, marking a significant milestone for both Club Med and Central Capital Group, one of Thailand’s leading business conglomerates.

#ClubMed #ClubMedKohSamui #ClubMedExclusiveCollection
Download high-resolution images:https://bit.ly/4r0xL5D

The event included a traditional ceremony as well as a symbolic planting of native Samui coconut seedlings, signifying a tribute to the locale as well as a brand new beginning and a vision of future success. This closely follows the signing of the Hotel Management Agreement (HMA) just earlier this year.

The highly anticipated Club Med Koh Samui resort will be a Club Med Exclusive Collection Resort, the third in this product range in the East and South Asia, and Pacific (ESAP) region. Club Med Exclusive Collection Koh Samui will mark the brand’s first Exclusive Collection Resort in Thailand and second in the country, following Club Med Phuket which opened its doors 40 years back in 1985.

This expansion of Club Med and the Exclusive Collection product range continues the upscale trajectory of Club Med’s global upgrade which was completed in 2024. Since then, the group has been focused on accelerating the development of new resorts around the globe, including both Premium All-Inclusive as well as Exclusive Collection resorts.

With the ambition to double the number of resorts globally by 2030, Club Med’s development expansion roadmap is well-paced to deliver outstanding new resorts such as Club Med South Africa (newly opened in July 2026) and a brand new beach resort Club Med Borneo in Kota Kinabalu, Malaysia (end of 2026).

Other upcoming projects by Club Med include opening of resorts in Canada, Italy, Oman and Indonesia in the next few years.

About Club Med

Club Med, founded in 1950 by Gérard Blitz, invented the all-inclusive holiday club concept, adding in activities especially for children with the creation of the Mini Club in 1967. Led by its pioneering spirit, Club Med seeks out exceptional destinations and sites. Today, Club Med is the world’s leading provider of upscale, all-inclusive holiday packages with a French touch for families, active couples and individuals. Present in 40 countries around the world, and with over 60 Premium and Exclusive Collection Resorts, Club Med offers a vacation to experience free spirit in exceptional destinations and sites. Club Med employs nearly 28,000 Gentle Organisers (G.Os) and Gentle Employees (G.Es), representing 110 nationalities.