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SuperX Forms Joint Venture with Zhonhen Electric to Revolutionize Global AI Data Center Power Infrastructure

Newly formed entity “SuperX Digital Power” will integrate the strengths of both companies to deliver advanced High-Voltage Direct Current (HVDC) solutions to the global market (excluding Mainland China, Hong Kong, and Macau), directly addressing the high energy consumption of AI computing with a next-generation, high-efficiency, low-cost power architecture.

SINGAPORE, Sept. 15, 2025 /PRNewswire/ — Super X AI Technology Limited (NASDAQ: SUPX) (“the Company” or “SuperX”) an AI infrastructure solutions provider, today announced that its wholly-owned subsidiary, SuperX AI Solution Limited, a company incorporated in the British Virgin Islands, has entered into a joint venture agreement with Enervell Power Pte. Ltd., a Singapore subsidiary of Hangzhou Zhonhen Electric Co., Ltd., (Shenzhen Stock Exchange: 002364) (“Zhonhen Electric”) and certain affiliates, related parties and designees of Zhonhen Electric, to establish a joint venture through a new entity incorporated in Singapore, SuperX Digital Power Pte. Ltd. Zhonhen Electric is one of the established providers in China’s digital power industry.

This strategic partnership marks a critical vertical integration for SuperX, extending its capabilities from AI compute infrastructure to core power technology. The joint venture is designed to solve one of the most pressing challenges of the AI era: exponential growth in energy consumption. It will combine Zhonhen Electric’s HVDC technology that is proven in large-scale AI Data Center (AIDC) deployments with SuperX’s global brand and AIDC expertise to offer customers a superior, end-to-end “Compute + Power” integrated solution.

HVDC: The Disruptive Power Architecture for AI Compute

As next-generation GPUs like the NVIDIA Blackwell push single-rack power consumption beyond 100kW, traditional alternating current (AC) power architectures have become a significant bottleneck for AI data center growth. The multiple AC-DC conversion steps in legacy systems lead to energy losses of approximately 10-15%, [1]increase system complexity, consume valuable floor space, and drive up the total cost of ownership (TCO).

HVDC technology fundamentally changes this paradigm by simplifying the power distribution path, enabling a “DC-to-chip” architecture. Its core advantages include:

  • Ultimate Energy Efficiency: Reduces power conversion stages from 4-5 to just 1-2, boosting end-to-end efficiency from approximately 85-90% [2]to over 96% and dramatically lowering electricity loss and operational expenditures (OPEX).
  • Higher Power Density & Smaller Footprint: Eliminates bulky Uninterruptible Power Supply (UPS) and power distribution units, freeing up as much as 50% of facility space to deploy more AI servers and maximize compute density.
  • Enhanced Reliability: A simpler architecture means fewer points of failure. HVDC is also natively compatible with battery energy storage systems, providing more stable power for mission-critical AI training workloads.
  • Lower Total Cost of Ownership (TCO): Through significant savings in electricity, reduced capital expenditure on equipment, and simplified maintenance, HVDC solutions can lower a data center’s TCO by over 20%.

Figure 1. SuperX PANAMA-HVDC jointly launched with Zhonhen
Figure 1. SuperX PANAMA-HVDC jointly launched with Zhonhen

Industry visionaries, including NVIDIA CEO Jensen Huang, have repeatedly highlighted the importance of power efficiency for AI industry[3]. With NVIDIA’s planned Rubin Ultra NVL576 expected to reach 600kW per rack after 2027, the disruptive energy efficiency of HVDC is shifting it from an “option” to a “necessity” for building next-generation AI data centers.

Zhonhen is the definitive leader and standard-setter for HVDC technology in China. Its solutions are trusted by the country’s top-tier technology and telecom giants—including China Mobile, China Telecom, Alibaba, Tencent, and Baidu—and have been massively deployed, proving their stability and performance in powering China’s core digital economy.

Synergistic Value: Empowering SuperX as a Global Full-Stack AI Infrastructure Leader

The partnership with Zhonhen Electric delivers immense strategic value to SuperX:

  1. Completes the “One-Stop-Shop” Solution: This venture extends SuperX’s capabilities from AI servers, liquid cooling, and networking to the very heart of the data center—the power system. SuperX will be able to offer a fully optimized solution from power-in to model-out, giving SuperX an edge over its competitors.
  2. Builds a Core Technology Moat: The joint venture enables SuperX to offer HVDC products that are deeply integrated with its AI servers and liquid cooling solutions, creating a “Compute + Cooling + Power” trifecta. This provides customers with unmatched performance and TCO.
  3. Secures a First-Mover Advantage Globally: By bringing Zhonhen Electric’s market-leading technology to the international stage through its global channels, SuperX can rapidly meet the urgent demand for fast-deployment, high-efficiency AI data centers, helping customers gain a competitive edge worldwide.

“The race in AI is also a race for energy efficiency,” said Kenny Sng, CTO of SuperX. “SuperX is proud to announce a strategic alliance with Zhonhen, the leading authority in China’s HVDC technology. This partnership represents a deep synergy between our respective technology roadmaps, culminating in the launch of ‘SuperX Digital Power’. This collaboration will establish a new global standard for energy-efficient AI data centers, empowering our clients to scale computational resources with operational efficiency and reduced environmental impact.

About Hangzhou Zhonhen Electric Co., Ltd. (002364.SZ)

Founded in 1996 and listed on the Shenzhen Stock Exchange (SZSE: 002364) since March 2010, Hangzhou Zhonhen Electric Co., Ltd. (“Zhonhen”) is one of the established digital energy companies dedicated to building a zero-carbon intelligent society. Zhonhen Electric provides end-to-end products and solutions for energy decarbonization across four key areas: Green ICT Infrastructure, Low-Carbon Transportation, New Power Systems, and Integrated Energy Services. Its offerings include High-Voltage Direct Current (HVDC) power systems for data centers, prefabricated power modules, and intelligent charging/swapping solutions. Headquartered in Hangzhou, China, Zhonhen is committed to its mission of “Making Energy Smarter” by building a more efficient, intelligent, and secure digital energy ecosystem. For more information, please visit: https://www.zhonhen.com/ 

About Super X AI Technology Limited (NASDAQ: SUPX)

Super X AI Technology Limited is an AI infrastructure solutions provider, and through its wholly-owned subsidiaries in Singapore, SuperX Industries Pte. Ltd. and SuperX AI Pte. Ltd., offers a comprehensive portfolio of proprietary hardware, advanced software, and end-to-end services for AI data centers. The Company’s services include advanced solution design and planning, cost-effective infrastructure product integration, and end-to-end operations and maintenance. Its core products include high-performance AI servers, High-Voltage Direct Current (HVDC) solutions, high-density liquid cooling solutions, as well as AI cloud and AI agents. Headquartered in Singapore, the Company serves institutional clients globally, including enterprises, research institutions, and cloud and edge computing deployments. For more information, please visit www.superx.sg

Contact Information

Product Inquiries: sales@superx.sg

Investor Relation: ir@superx.sg

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Safe Harbor Statement

This press release may contain forward-looking statements. In addition, from time to time, we or our representatives may make forward-looking statements orally or in writing. We base these forward-looking statements on our expectations and projections about future events, which we derive from the information currently available to us. You can identify forward-looking statements by those that are not historical in nature, particularly those that use terminology such as “may,” “should,” “expects,” “anticipates,” “contemplates,” “estimates,” “believes,” “plans,” “projected,” “predicts,” “potential,” or “hopes” or the negative of these or similar terms. In evaluating these forward-looking statements, you should consider various factors, including: our ability to change the direction of the Company; our ability to keep pace with new technology and changing market needs; and the competitive environment of our business. These and other factors may cause our actual results to differ materially from any forward-looking statement.

Forward-looking statements are only predictions. The reader is cautioned not to rely on these forward-looking statements. The forward-looking events discussed in this press release and other statements made from time to time by us or our representatives, may not occur, and actual events and results may differ materially and are subject to risks, uncertainties, and assumptions about us. We are not obligated to publicly update or revise any forward-looking statement, whether as a result of uncertainties and assumptions, the forward-looking events discussed in this press release and other statements made from time to time by us or our representatives might not occur.

[1] This loss is cumulative. A 2010 IEEE study on legacy data center power systems found that the multiple AC-DC conversion steps resulted in a total energy loss of approximately 17%. Source: N. Bourgeois et al., “Powering the data centres of the future,” in 2010 IEEE International Telecommunications Energy Conference, 2010, pp. 1-7.

[2] The 85-90% efficiency range is characteristic of traditional AC power distribution architectures where losses are compounded at each conversion stage. A typical path from the facility entry to the server rack involves conversions at the uninterruptible power supply (UPS), the power distribution unit (PDU), and finally the server’s internal power supply unit (PSU). 

[3] During the GTC 2025 keynote, NVIDIA CEO Jensen Huang stated, “Every single data center will be power limited… it is absolutely essential that we have the most energy-efficient compute architecture possible.” Source: NVIDIA, “GTC March 2025 Keynote with NVIDIA CEO Jensen Huang,” YouTube, March 19, 2025, timestamp 1:14:28. Available at: https://www.youtube.com/watch?v=_waPvOwL9Z8

 

Univers Named a Leader in 2025 Gartner® Magic Quadrant™ for Global Industrial IoT Platforms

SINGAPORE, Sept. 15, 2025 /PRNewswire/ — Univers, a global leader in AI for Energy, today announced that it has been positioned as a Leader in the 2025 Gartner Magic Quadrant for Global Industrial IoT Platforms.

Univers Named a Leader in 2025 Gartner® Magic Quadrant™ for Global Industrial IoT Platforms
Univers Named a Leader in 2025 Gartner® Magic Quadrant™ for Global Industrial IoT Platforms

The Gartner assessment recognizes Univers for its EnOS™ platform for its ability to execute and its completeness of vision.

In just seven years, Univers has built a global AI-first platform that now connects 365 million devices and manages 845 GW of renewable energy — nearly one-fifth of the world’s total capacity.

“Being recognized as a Leader in the Magic Quadrant so early in our journey is a proud moment for Univers.  This recognition underscores the company’s ability to innovate at speed and deliver impact at scale,” said Michael Ding, Global Executive Director, Univers. “It affirms that that an AI-first approach to energy and industrial IoT delivers tangible business results and sustainability outcomes for customers worldwide. We believe that this recognition validates our vision and fuels our commitment to help industries decarbonize and innovate at scale.”

Rather than siloed tools, EnOS™ offers a unified platform where industries can move from automation to autonomous intelligence. With applied AI, enterprises can detect risks before they escalate, balance energy flows across global operations, and accelerate the transition to low-carbon systems.

Univers’ rapid rise also reflects its ecosystem strength: global integrators are embedding EnOS™ into large-scale deployments, while technology partners extend AI capabilities into new industrial and energy use cases.

“Looking ahead, Univers remains focused on pushing the boundaries of AI for Energy, advancing from monitoring and optimization to fully autonomous operations and empowering industries worldwide to achieve resilience, efficiency, and sustainability at scale,” added Michael.

Gartner, Magic Quadrant for Global Industrial IoT Platforms, By Scot Kim, Sudip Pattanayak et al., 8 September 2025

GARTNER is a registered trademark and service mark of Gartner, Inc. and/or its affiliates in the U.S. and internationally, Magic Quadrant is a registered trademark of Gartner, Inc. and/or its affiliates and is used herein with permission. All rights reserved. Gartner does not endorse any vendor, product or service depicted in its research publications and does not advise technology users to select only those vendors with the highest ratings or other designation. Gartner research publications consist of the opinions of Gartner’s Research & Advisory organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose.

About Univers

Univers is a global leader for AI in Energy.

Univers’ EnOS™ platform empowers enterprises across industries to solve complex energy challenges with intelligent, data-driven insights.

With 365 million devices connected, 845GW of renewable energy managed, and a global network of 800+ customers, we are the only global technology partner offering a truly comprehensive, end-to-end energy management solution, supporting enterprises at every stage of their energy transition journey.

For more information, please visit univers.com.

MINT Incorporation Limited Announces the Launch of New Subsidiary, Axonex Intelligence Limited, Expanding into Smart Facility Management Solutions


HONG KONG SAR – Media OutReach Newswire – 15 September 2025 – MINT Incorporation Limited (NASDAQ: MIMI) (“MINT” or the “Company”), a leading Hong Kong-based provider of integrated interior design and fit out works, today announced the official launch of its wholly owned subsidiary, Axonex Intelligence Limited (“Axonex”), a company incorporated with limited liability under the laws of Hong Kong, marking MINT’s expansion into the technology realm with the fast-growing smart facility management sector. Building on this foundation, MINT is extending its expertise to harness robotics, IoT, and AI technologies to enhance the way properties are managed and experienced.

Axonex provides total solutions for smart facility management, integrating advanced technologies to improve efficiency, safety, and user experience across different property types. Its key capabilities include:

  • Robotic solutions to automate routine facility management tasks, improve efficiency, and reduce manpower needs.
  • Object identification and human posture recognition for enhanced security and operational monitoring.
  • Digital twin solutions enabling real-time visualization and management of facilities.
  • AI-powered analytics to optimize maintenance, space utilization, and resource allocation.

Axonex is set to serve a diverse range of clients, including shopping malls, government premises, residential complexes, and warehouses. By leveraging its design background and new technological focus, Axonex aims to provide a holistic approach to property and facility management.

To support its solutions, Axonex is collaborating with technology partners such as AIMO and Sharp Peak, ensuring strong hardware and software integration.

With this strategic move, MINT reaffirms its commitment to innovation and its mission to provide comprehensive solutions that blend design excellence with cutting-edge technology.

Forward Looking Statements

This press release contains forward-looking statements. In addition, from time to time, we or our representatives may make forward-looking statements orally or in writing. We base these forward-looking statements on our expectations and projections about future events, which we derive from the information currently available to us. Such forward-looking statements relate to future events or our future performance, including: our financial performance and projections; our growth in revenue and earnings; and our business prospects and opportunities. You can identify forward-looking statements by those that are not historical in nature, particularly those that use terminology such as “may,” “should,” “expects,” “anticipates,” “contemplates,” “estimates,” “believes,” “plans,” “projected,” “predicts,” “potential,” or “hopes” or the negative of these or similar terms. In evaluating these forward-looking statements, you should consider various factors, including: our ability to change the direction of the Company; our ability to keep pace with new technology and changing market needs; and the competitive environment of our business. These and other factors may cause our actual results to differ materially from any forward-looking statement. Forward-looking statements are only predictions. The forward-looking events discussed in this press release and other statements made from time to time by us or our representatives, may not occur, and actual events and results may differ materially and are subject to risks, uncertainties, and assumptions about us. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include the risks and uncertainties described in the Company’s annual report on Form 20-F for the year ended March 31, 2025. We are not obligated to publicly update or revise any forward-looking statement, whether as a result of uncertainties and assumptions, the forward-looking events discussed in this press release and other statements made from time to time by us or our representatives might not occur.

Hashtag: #MINTIncorporation #AxonexIntelligence

The issuer is solely responsible for the content of this announcement.

About MINT Incorporation Limited

The Company is a Hong Kong-based interior design and fit out works provider, with a strategic focus on providing integrated and industry-specific interior design and fit out works for commercial properties. The Company’s work encompasses offices of different industries and various kinds of retail stores with a view to reflect its customers’ corporate values and conceptualizing our customers’ brands. The Company’s commercial projects cover internationally renowned retail stores, F&B outlet chains and offices and other premises of a premier charitable organization in Hong Kong. The Company also provides integrated interior design and fit out works for luxury residential properties in order to enhance both the aesthetics and functionality of the interior space.

About Axonex Intelligence Limited
Axonex Intelligence Limited, a company incorporated with limited liability under the laws of Hong Kong and subsidiary of MINT Incorporation Limited, delivers comprehensive solutions for smart facility management through the integration of robotics, IoT devices, and AI-powered analytics. By enabling real-time monitoring, predictive insights, and digital twin technologies, Axonex helps clients optimize operations and elevate user experiences across diverse property types. Guided by its vision of being a one-stop partner, Axonex is committed to helping organizations seamlessly integrate cutting-edge technologies into their daily operations.

TCTM Kids IT Education Inc. Announces Name Change to VisionSys AI Inc.

BEIJING, Sept. 15, 2025 /PRNewswire/ — TCTM Kids IT Education Inc. (NASDAQ: VSA) (“VSA” or the “Company“), an emerging technology services company, specializing in brain machine interaction businesses leveraging the core algorithms and related software and hardware systems, is pleased to announce that it has changed its name to “VisionSys AI Inc” after receiving the Certificate of Incorporation on Change of Name from the Registry of Companies, Cayman Islands, on September 10, 2025. The change of name will be effective on Nasdaq on September 19, 2025. The Company’s ADSs will continue trading on the Nasdaq Capital Market under the trading symbol “VSA”, and the CUSIP number shall remain unchanged.

About VisionSys AI Inc (formerly known as TCTM Kids IT Education Inc.)

VSA is an emerging technology services company, specializing in brain machine interaction businesses leveraging the core algorithms and related software and hardware systems. We are dedicated to advancing AI-powered healthcare and biotech solutions that transform industries. Our mission is to empower individuals and organizations through intelligent systems, bridging innovation with real-world impact to create a smarter, more connected future.

Safe Harbor Statement

This announcement contains forward-looking statements made under the “safe harbor” provisions of Section 21E of the Securities Exchange Act of 1934, as amended, and the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates,” “confident” and similar statements. Such statements are based upon management’s current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond the Company’s control. Further information regarding these and other risks, uncertainties or factors is included in the Company’s filings with the U.S. Securities and Exchange Commission. The Company does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under law.

For further information, please contact:

Investor Relations Contact
VisionSys AI Inc (formerly known as TCTM Kids IT Education Inc.)
Email:  info@visionsysai.com 

The Korea Industry Daily: Industrial AI EXPO 2025 Concludes, Marking Milestone in Korea’s AI-Driven Industrial Transformation

SEOUL, South Korea, Sept. 15, 2025 /PRNewswire/ — The first-ever Industrial AI EXPO wrapped up at COEX Magok Convention Center after a three-day run from September 3 to 5, positioning itself as a key platform for accelerating the adoption of artificial intelligence across Korea’s industrial sectors.

The first-ever Industrial AI EXPO wrapped up at COEX Magok Convention Center after a three-day run from September 3 to 5, positioning itself as a key platform for accelerating the adoption of artificial intelligence across Korea’s industrial sectors.
The first-ever Industrial AI EXPO wrapped up at COEX Magok Convention Center after a three-day run from September 3 to 5, positioning itself as a key platform for accelerating the adoption of artificial intelligence across Korea’s industrial sectors.

The exhibition brought together 133 companies across 320 booths, unveiling a wide range of industrial AI equipment and solutions for the first time. The event opened with a series of high-level activities, including a memorandum of understanding (MOU) on building a data-sharing ecosystem for manufacturing and a Minister of Trade, Industry and Energy Award ceremony, recognizing 25 individuals and organizations for their contributions to industrial digital transformation and AI utilization.

Government officials and industry leaders—including executives from HD Hyundai, LG CNS, Microsoft Korea, Dassault Systèmes, HP Korea, Salesforce, and major domestic institutions—attended the opening ceremony, underscoring collective commitment to advancing industrial AI.

Vertical AI Showcases and Technology Debuts

The expo highlighted 12 key industrial AI task areas, covering market forecasting, supply chain optimization, process control, predictive maintenance, safety, workforce training, and cybersecurity. Exhibitors demonstrated how AI can improve efficiency and resilience in manufacturing and beyond.

Notably, HD Hyundai shared AI adoption cases from shipbuilding and construction equipment, while debuting its broader AIX (AI Transformation) strategy. Robotics, on-device AI, and physical AI technologies also made their first appearances, reflecting the next phase of industrial automation.

Global players including Microsoft, Dassault Systèmes, HP, NVIDIA (with domestic partner Leaders Systems), and Salesforce joined with Korean partners to showcase AI-driven innovations in manufacturing, customer management, and design—expanding both domestic B2B pipelines and global collaboration opportunities.

Conferences, Forums, and Business Networking

Beyond the exhibition floor, the event hosted a series of programs designed to strengthen the industrial AI ecosystem:

  • Industrial AI Conference – case studies and business models from leading corporations
  • AI-Tech Seminars – new technology launches and commercialization success stories
  • 1:1 Business Matching – connecting suppliers with demand-side enterprises
  • Startup IR and Investment Networking – pitches, mentoring, and investor sessions
  • Industrial AI International Certification Forum – discussions on reliability, safety, and standards with global stakeholders

Visitors also participated in guided docent tours, LG Science Park programs, and interactive events that highlighted industrial AI use cases across physical AI, manufacturing AI, and AI agent domains.

Building Korea’s Industrial AI Ecosystem

Lee Gil-seon, Executive Managing Director of the Korea Smart Manufacturing Industry Association, emphasized:

“As the country’s first vertical AI exhibition, Industrial AI EXPO presented a wealth of successful application cases. By serving as a matching platform between supply and demand, the expo will accelerate the adoption of AI across industries, strengthen Korea’s industrial AI ecosystem, and enhance global competitiveness.”

The successful conclusion of the Industrial AI EXPO 2025 underscored Korea’s determination to leverage artificial intelligence not only as a technological tool but as a transformative driver of industrial innovation.

Biostar Pharma Successively Achieved First Patient Dosing for Two Phase II/III Multiregional Clinical Trials of Utidelone Capsule (UTD2)

SAN FRANCISCO, Sept. 15, 2025 /PRNewswire/ — Biostar Pharma, Inc., the US subsidiary of Beijing Biostar Pharmaceuticals Co., Ltd. (“Biostar”, Stock Code: 2563.HK) which is a synthetic biology driven biopharma company focusing on the discovery, development and commercialization of innovative oncology drugs, is pleased to announce that the first patients have been dosed for two phase II/III multiregional clinical trials (MRCT) of “Utidelone Capsule (UTD2) first-line treatment for locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma” (NCT06841679) and “UTD2 treatment for platinum-resistant advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer” (NCT07044349) on September 11, 2025 and September 12, 2025, respectively.

Utidelone has demonstrated excellent clinical data in gastric cancer: in a completed Phase II study of Utidelone Injection (UTD1) combined with PD-1 inhibitor and oxaliplatin for the first-line treatment of unresectable locally advanced or recurrent/metastatic HER2-negative gastric cancer, 23 patients had completed efficacy evaluation. Among them, 15 achieved partial response (PR) and 8 achieved stable disease (SD), resulting in a 65.2% objective response rate (ORR) and 100% clinical benefit rate (CBR). The median progression-free survival (mPFS) was 6.1 months. The combination regimen was generally well-tolerated. Most treatment-related adverse events (TRAEs) were Grade 1-2, reversible, and manageable. The longest treatment duration received by a patient was 22 cycles [1]. Consequently, Utidelone was granted an Orphan Drug Designation by the U.S. FDA for the treatment of advanced gastric cancer.

Besides gastric cancer, Utidelone has also shown considerable potential for treating ovarian cancer in previous clinical studies. A US Phase I clinical study of UTD2 as a monotherapy for advanced solid tumors had 12 evaluable patients, including one ovarian cancer patient with a complete response (CR) and another with PR, who had previously undergone 7 and 9 lines of therapy, respectively [2]. A Phase II clinical study of UTD1 as monotherapy for the treatment of advanced solid tumors had 10 evaluable patients in advanced ovarian cancer cohort, among them there were 1 PR and 3 SD.

Compared to taxanes, which are difficult for oral formulation development, Utidelone is not susceptible to P-glycoprotein thus cannot be pumped out of the cancer cell by P-glycoprotein and has the advantage for higher oral bioavailability and lower risk of developing cross-resistance. By utilizing its technology platform, Biostar developed Utidelone Capsule, and its efficacy and safety have been confirmed in both US and China’s studies. Utidelone Capsule will significantly improve the convenience of administration, compliance of patients, decrease in treatment cost and ease of combination therapy with other oral anti-cancer drugs, and more suitable for adjuvant or maintenance therapy. Beyond gastric and ovarian cancers, Biostar is actively planning and advancing multiple clinical studies to expand UTD2’s indications, including breast cancer adjuvant intensification therapy, pancreatic cancer, esophageal cancer, colorectal cancer, and so on.

About NCT06841679 Study

This study is a multi-national, open-label, randomized phase II/III clinical study of UTD2 combined with standard of care to evaluate the efficacy and safety in first-line patients with locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma, untreated with systemic treatment in the advanced setting. For the Phase II part, 78 subjects are planned to be enrolled in China, US, Europe and Japan. Its primary objectives are to evaluate the safety, efficacy, and pharmacokinetic profile of UTD2 in combination therapy. The Phase III part plans to enroll 700 subjects across multiple countries/regions. The primary endpoint is overall survival (OS), with secondary endpoints including PFS, ORR, and safety.

About NCT07044349 Study

This study is a multi-national, open-label, randomized Phase II/III clinical trial of UTD2 for the treatment of patients with platinum-resistant advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer. The Phase II part plans to enroll approximately 84 subjects. Its primary objective is to evaluate the safety, efficacy, and pharmacokinetic (PK) characteristics of UTD2 under different dosing regimens in the target patient population and to recommend a dose for Phase III. The Phase III part plans to enroll 480 subjects and is planned to be conducted in multiple countries and regions worldwide. Its primary objective is to evaluate the efficacy and safety of UTD2 compared to the investigator’s choice of standard treatment in the target patient population. The primary endpoint is PFS, with secondary endpoints including OS, ORR, and others.

About Utidelone

Utidelone is a new-generation genetically engineered microtubule inhibitor, and has similar mechanism of action with that of taxanes while demonstrating multiple advantages, including better anti-tumor activity, broader anti-tumor spectrum, better safety profile with very low hematologic toxicity, effective against multidrug-resistant tumors, less prone to developing drug resistance, capability of crossing the blood-brain barrier to prevent and treat brain tumors, and high oral bioavailability. Biostar has developed two formulations of Utidelone: injection (UTD1) and capsule (UTD2). UTD1 has been launched in China in 2021 for the treatment of metastatic breast cancer (MBC), who have progressed after at least one anthracycline- or taxane-containing chemotherapy regimen. The phase III study data showed that UTD1 plus capecitabine achieved both PFS and OS benefits versus capecitabine for heavily pretreated MBC patients, and the results were orally presented twice at ASCO annual meetings and published in prestigious journals [3-4].

About Biostar

Biostar is an integrated biopharma company focusing on the development of innovative anti-cancer drugs utilizing its synthetic biology R&D platform. The company is listed on the Hong Kong Stock Exchange (HK 2563) in 2024. We are actively selecting reliable global partners through out-licensing or co-development of Utidelone assets. We believe that our strong capabilities of R&D and manufacturing, coupled with our enriched commercial expertise, make us the preferred partner for global biopharmaceutical companies who share our goal of bringing innovative anti-cancer products to patients around the world. For additional information on partnering with Biostar, please contact our business development team at bd@biostar-pharma.com.

Reference
[1] 2025 ASCO Abstract #: 4040
[2] 2025 ASCO Abstract #: 3030
[3] B. Xu, T. Sun, Q. Zhang, et al. Annals of Oncology, 2021, 32(2): 218-228
[4] Pin Zhang, Tao Sun, Qingyuan Zhang, et al. Lancet Oncol 2017; 18: 371-83

Rona Therapeutics Announces IND Filing of RN3161, a Highly Potent and Durable INHBE siRNA for Obesity

SHANGHAI and SANTA BARBARA, Calif., Sept. 15, 2025 /PRNewswire/ — Rona Therapeutics, a global leader in developing next-generation RNAi therapeutics, announced today the successful submission of RN3161 to the Australian Human Research Ethics Committee (HREC). RN3161 is a proprietary GalNAc-conjugated siRNA targeting INHBE, a novel therapeutic mechanism for adults with overweight and obesity.

Obesity is a global health crisis, but treatments often cause significant side effects, including nausea, vomiting and muscle loss, and are difficult to adhere to over time. The INHBE gene, found in the liver, produces Activin E, a protein that helps control fat metabolism. People with certain INHBE gene changes have better fat distribution, body composition, healthier cholesterol levels, and lower risks of type 2 diabetes or heart disease. This makes INHBE a promising target for improved obesity treatments.

RN3161, a novel siRNA developed through Rona’s proprietary GAIA™ platform, targets INHBE to reduce fat while preserving lean mass, setting it apart from existing treatments. Engineered with optimized GalNAc-conjugated delivery and chemical modifications, it minimizes off-target risks and demonstrated more than 90% INHBE mRNA knockdown in monkeys with a low single dose. RN3161’s long-lasting gene silencing supports Q6M to Q12M dosing, enhancing patient adherence and suitability for long-term obesity management. As the fourth clinical candidate from GAIA™, RN3161 underscores Rona’s consistent excellence to advance innovative RNAi medicines from bench to bedside.

Alex M. DePaoli, CMO, said, “The successful HREC submission of RN3161 marks an exciting step in advancing a novel therapeutic to treat obesity. RN3161 offers the potential benefit of losing weight with preserved muscle mass, but also the potential to enhance the metabolic benefits associated with fat loss. Further, infrequent dosing offers better adherence and weight loss maintenance. This represents a potential new paradigm in the field of obesity management. “

Stella Shi, CEO, added, “RN3161 could maintain high quality weight loss post GLP-1 era. This milestone reflects our ambition to reshape the obesity treatment paradigm for healthier weight loss. It renews our mission to bring innovative and durable therapies to patients worldwide. We’re committed to translating cutting-edge siRNA technologies into therapies in multiple areas.”

About Rona Therapeutics

Rona Therapeutics is a pioneering RNAi platform company dedicated to addressing cardiometabolic diseases and obesity worldwide. Rona’s pipeline is fueled by highly effective and proprietary liver and extra-hepatic delivery platforms. The company has raised $100M USD since inception.

Sercomm Showcases Next-Gen RDK Video Accelerator STB Based on Broadcom BCM74116 at the RDK Global Summit 2025

AMSTERDAM, Sept. 15, 2025 /PRNewswire/ — At the RDK Global Summit, Sercomm Corporation (TWSE: 5388), a leading global provider of entertainment and broadband equipment, today introduced its newest RDK Video Accelerator based on the latest Broadcom BCM74116 integrated System on Chip (SoC). This new state-of-the-art STB will also use the latest RDK7 software release. 

RDK is an open-source software platform that standardizes core functions used in video and broadband devices. RDK enables service providers to control their device diagnostics data, business models, and apps to improve the customer experience and drive business results. The new Sercomm STB platform is designed to accelerate integration with operator user interfaces and video services, enabling speedier product launches, robust long-term support, and pre-integrated with several premium streaming apps. 

Sercomm’s RDK-7 Streamer with NPU
Sercomm’s RDK-7 Streamer with NPU

“Sercomm’s market innovation continues with the launch of their new RDK7-ready set-top box,” said Jason Briggs, President and GM of RDK. “As a Preferred Member of the RDK community, we’re very proud to see Sercomm’s ongoing commitment to serve our expansive operator community across the globe.”

“We are proud to announce our latest RDK Video Accelerator together with our partners Broadcom and RDK,” said Amir Mobini, Vice President of Global Product Marketing at Sercomm. “As a vertically-integrated, globally diverse OEM with a strong record as a leading shipper of RDK streaming set-top boxes worldwide, Sercomm stands ready to support operators who are looking for a set-top box platform solution based on the latest RDK architecture that can be quickly launched and tightly integrated into their subscriber services and offerings. This platform is one of the first of its kind to offer integrated edge AI powering a new wave of monetization opportunities for our operator partners.”

About Sercomm

Founded in 1992, Sercomm (TWSE: 5388) is a global leader in providing integrated networking and telecom solutions. Partnering with the world’s top service providers, system integrators, and leading technology companies, Sercomm’s expertise in designing and manufacturing innovative, customized solutions makes embedding connectivity more accessible across the globe.

For more information, please visit https://www.sercomm.com/