22.6 C
Vientiane
Monday, October 20, 2025
spot_img
Home Blog Page 508

Well-Known Chinese Brand Publishes Landmark Paper in Springer Nature’s Top Journal Nano-Micro Letters

A leading Chinese kid’s brand’s sunscreen technology sets a new global benchmark.

GUANGZHOU, China, Aug. 28, 2025 /PRNewswire/ — Hi!papa, a leading Chinese kid’s brand, recently published a paper on sunscreen technology in Nano-Micro Letters, a top international journal under Springer Nature with an impact factor of 36.3. The study is the world’s first to apply advanced materials technology from mobile phone manufacturing to skincare, breaking through a 20-year bottleneck in sunscreen innovation and setting a new benchmark for the global sunscreen industry.


Nano-Micro Letters is a peer-reviewed, top-ranked international journal in materials science, covering interdisciplinary research on nano- and microscale structures across physics, chemistry, biology, and pharmacy. In the 2025 Journal Citation Reports, the journal ranked in the top two percent globally in three disciplines. Its content highlights industrial breakthroughs that often enter daily life within a short period of time. Hi!papa’s inclusion highlights the exceptional weight of this achievement.

This scientific breakthrough reflects the cross-disciplinary research approach of Associate Professor Qiu Ling of Tsinghua University, Chief Scientific Advisor of Hi!papa.. His background includes work at the joint research platform of the Shenzhen Geim Graphene Research Center and Tsinghua University Shenzhen Research Institute, established by 2010 Nobel Prize winner André Geim. In collaboration with major consumer electronics companies, Prof. Qiu pioneered the use of modified boron nitride in mobile phone cooling systems, highlighting the potential of structural modification in light and heat management.

Drawing on graphene’s light transmission and its ability to block ultraviolet rays and harmful substances, Hi!papa’s team, led by Associate Professor Qiu Ling of Tsinghua University, Chief Scientific Advisor of Hi!papa, redefined sunscreen design to create a Chinese Invisible Sunscreen Film. The global beauty industry takes a cautious approach to applying materials science across disciplines, but Hi!papa has broken new ground by adapting molecular structure optimization methods used in mobile phone manufacturing to skincare, achieving a breakthrough in healthy, invisible, and non-whitening sun protection.

The advanced material minimizes skin burden from sunscreen use, ushering in a new era of healthy sun protection. The Invisible Film technology reduces residue and penetration of traditional sun protection, while delivering comprehensive defense for skin health. By using structural modification and metal doping to reconstruct two-dimensional lamellar titanium dioxide, the team has broken through an almost 20-year technological bottleneck.

Over the past two decades, few advances in sunscreen have been recognized as true technological breakthroughs by leading academic journals. Most claimed improvements focus on adjusting particle size, adding moisturizers, or combining physical and chemical sunscreen. By contrast, Hi!papa’s innovative Invisible Sunscreen Film technology achieves fundamental progress at the materials level, paving the way for safer, more effective products and setting a new benchmark for the industry.

Founder and CEO, Xu Yujiangsheng, commented: “This achievement not only advances sunscreen technology through the tremendous potential of cross-disciplinary research, but also represents a meaningful contribution from a Chinese brand to global skincare innovation. Hi!papa will remain research-driven, bringing safer and more scientifically grounded skincare to new generations worldwide.”

About Hi!papa

Backed by LVMH-affiliated investment, Hi!papa is a leading scientific and functional skincare brand for kids. It independently established the Xihe Laboratory, China’s first research center dedicated to children and teen’s skincare, and has collaborated with leading experts including teams from Tsinghua University. In just four years, the brand has grown to a billion-yuan scale and now holds 60 patents and 29 special sunscreen certifications. According to Euromonitor International, Hi!papa is ranked as Asia’s No. 1 baby and child sunscreen brand, maintaining the top spot for four consecutive years, underscoring its global recognition for innovation and growth potential, underscoring its global recognition of innovation and growth potential.

Coventry Responds to Lapetus’s Secrecy Claim

Urges transparency on life expectancy accuracy

Following Lapetus’s imminent closure, argues elimination of any claim to trade secret protection

TALLAHASSEE, Fla., Aug. 28, 2025 /PRNewswire/ — Coventry First LLC (“Coventry”), the market leader in life settlements, this week filed a legal response opposing Lapetus Solutions, Inc.’s (“Lapetus”) attempt to block disclosure of statutorily required life expectancy audit reports. The filing underscores Coventry’s long-held view that the integrity of the life settlement market demands transparency around the accuracy of life expectancy estimates. At the same time, Coventry filed its own motion for summary judgment, arguing that Lapetus’s announced shutdown on August 31, 2025, should eliminate any claim to trade secret protection.

Florida law requires life expectancy providers to submit triennial life expectancy audit reports to Florida’s Office of Insurance Regulation (“OIR”) for the five calendar years preceding each audit. Because these reports measure the accuracy of prior predictions and do not contain the proprietary methods used to generate such predictions, Coventry argues that they are not entitled to trade secret protection. In addition, Lapetus itself has repeatedly publicized its reported “accuracy” in marketing materials, public statements, and direct communications with Coventry. For these reasons, Coventry contends that a ruling in Lapetus’s favor is inappropriate and should be denied.

“Investors and regulators alike need confidence that life expectancy estimates are accurate, reliable, and compliant with actuarial standards,” said Alan H. Buerger, Coventry’s Executive Chairman. “Transparency protects investors and the integrity of the entire life settlement market. As the creator of the secondary market for life insurance, we maintain our commitment to advocating for consumer rights and are active in promoting rigorous industry regulations, as demonstrated by our response to Lapetus’s claim.”

Lapetus’s Imminent Closure Should Make Trade Secret Claims Moot

In an email dated August 18, 2025, Lapetus CEO, Co-Founder and Chief Scientist S. Jay Olshansky, Ph.D. confirmed that the company will be “shutting the doors to all of its business lines on the 31st of August.” After that date, Coventry argues that the audit results will not meet the statutory definition of trade secrets because they will not be used “in the operation of a business” or to confer any competitive advantage.

Accordingly, Coventry asserts that it is entitled to summary judgment requiring disclosure of the audit results.

Importance of Accurate Life Expectancies  

The stakes extend beyond this litigation. Life expectancies are the linchpin of life settlement valuations. If estimates are routinely too short, the resulting distortions could mislead investors, cause substantial losses, and erode confidence in the market. As Coventry Executive Chairman Alan H. Buerger declared in support of the motion, independent academic review shows Lapetus’s life expectancies were shorter in more than 80% of tested cases compared to peers, with an actual-to-expected ratio of just 31%, far short of the 96.3% accuracy rate claimed by Lapetus.

Florida regulators previously recognized this danger after the $800 million Mutual Benefits fraud, where chronically short life expectancies fueled one of the largest Ponzi schemes in state history. As a consequence of Mutual Benefits, the Legislature mandated that life expectancy providers be registered with the OIR and file regular audit reports.

About Coventry

Coventry is the leader and creator of the secondary market for life insurance. For more than 20 years, we have been driving the industry forward and expanding opportunities for life insurance policyowners. Coventry’s deep experience combined with a fierce commitment to consumer rights makes Coventry the clear market leader, a position we use to raise industry standards and expand consumer choice. To date, we have delivered more than $6 billion to policyowners who no longer have a need for their policies. To learn more about Coventry, please visit Coventry.com.

Prosek Partners for Coventry
Andrew Merrill / Kiki Tarkhan
Pro-Coventry@prosek.com

SANY Reports Strong First Half 2025 Results, Delivering Profitable Growth

Revenue Up 15% to $6.24 Billion; Operating Cash Flow Up 20% to $1.42 Billion

SHANGHAI, Aug. 28, 2025 /PRNewswire/ — On August 21, SANY Heavy Industry released its interim results for the first half of 2025. The company executed on its strategy of globalization, digitalization, and decarbonization, achieving balanced growth across scale, expansion, and profitability through continued product innovation and disciplined operations. Revenue reached $6.24 billion, a year-on-year increase of 14.96%; net income attributable to shareholders was $0.73 billion, up 46.00%; operating cash flow was $1.42 billion, an increase of 20.11%. Net income margin rebounded to 11.65%, up 2.50 p.p. compared to the same period last year. As of June 30, 2025, total assets stood at $21.54 billion, while net equity attributable to shareholders reached $10.30 billion.

SANY Reports Strong First Half 2025 Results, Delivering Profitable Growth
SANY Reports Strong First Half 2025 Results, Delivering Profitable Growth

Global Expansion and Continued Progress in Sustainability

In the first half of 2025, international revenue from the company’s core businesses reached $3.69 billion, up 11.72%, accounting for 60.26% of total revenue. Sales in the AsiaAustralia region rose 16.3% to $1.606 billion; Europe contributed $0.863 billion, up 0.66%; the Americas generated $0.71 billion, an increase of 1.36%; and Africa saw strong growth with revenue surging 40.48% to $0.509 billion

Benefiting from factors such as a more optimized product structure, SANY’s gross margin on international business reached 31.18% in the first half of 2025, an increase of 1.04 p.p. 

The company also accelerated its renewable energy initiatives, launching over 30 environmentally responsible products during the period and securing 30 authorized low-carbon patents on core components. The service life of reinforced slewing reducers GS23 and GS27 surpassed 15,000 hours. The successful introduction of the 100-ton excavator slewing reducer addressed a technology gap in the ultra-durable excavator reducer segment. 

Strengthening Core Businesses and R&D

SANY reported excavating machinery revenue of $2.45 billion, up 15.00% year-on-year. Revenue from concrete machinery reached $1.04 billion, down 6.49%, while hoisting machinery rose 17.89% to $1.09 billion. Piling machinery revenue increased 15.05% to $0.19 billion, and road machinery revenue surged 36.83% to $0.3 billion.

During the period, the company invested $0.3 billion in R&D and filed 246 patent applications (excluding software copyrights), of which 131 were invention patents.

Looking ahead, the company will continue to invest in innovation and modernizing operations, building a more resilient, competitive industry ecosystem while delivering sustainable growth and long-term value for shareholders. 

 

 

EPWK Launches International Platform, Aims to Bridge Global Markets for Creative Services

XIAMEN, China, Aug. 28, 2025 /PRNewswire/ — EPWK (NASDAQ: EPWK), a Xiamen-based online marketplace for creative services, has launched its international platform at intl.epwk.com, positioning itself as a global gateway for digital service outsourcing. The company specializes in connecting SMEs with freelance talent across diverse fields including design, software development, AI, content, and marketing.

Strong Market Position Backed by Scale and Data

EPWK operates in a high-potential sector driven by three key forces: first, the global creative services market is expanding, with growing demand for flexible and efficient digital solutions as businesses accelerate their shift online. Second, AI is reshaping content production—technologies like AIGC (AI-Generated Content) are lowering entry barriers and boosting productivity. EPWK’s “AI Assistant” is built to leverage this shift. Third, China offers a large pool of skilled, cost-effective creative talent, giving EPWK a competitive edge in serving global demand.

According to Frost & Sullivan’s 2023 report on China’s crowdsourcing sector, EPWK ranks among the top platforms by gross merchandise value (GMV). The platform processed $350 million in GMV in 2023, placing it second nationwide. As of June 2024, EPWK has over 25.6 million registered users across 2,800+ regions, with a cumulative GMV exceeding $1.67 billion and over 4.6 million projects completed.

Behind EPWK’s growth metrics is a long-standing focus on service quality and user experience. The platform enforces strict vetting and reputation systems to ensure provider reliability and professional standards. A robust transaction framework protects both parties’ rights, promoting a fair, transparent, and secure environment. This consistent emphasis on trust and quality has earned EPWK a strong reputation across the industry.

EPWK is certified as a national high-tech enterprise in China, and has contributed to national tech initiatives and policy frameworks. It led the development of China’s first industry standard for creative skill-sharing platforms.

AI-Powered Service Matching and Workflow Tools

Since its founding, EPWK has consistently invested in R&D to build a service infrastructure powered by big data and AI. Its proprietary task recommendation engine uses deep learning to analyse user behaviour, skill tags, and task requirements, enabling highly accurate matching between clients and service providers. This system significantly reduces the time and effort needed to find the right partner, improving transaction success rates and user satisfaction.

The platform supports over 300 service categories across design, development, AI, marketing, video, and copywriting—catering to the diverse needs of SMEs. From logo and animation design to web and software development, from industrial and interior design to branding, copywriting, and trademark registration, EPWK offers a full range of creative services through a single, integrated platform.

The company also rolled out “EPWK AI Assistant,” built on DeepSeek’s LLM, which automates demand analysis, task publishing, and progress tracking. It can interpret large volumes of task data to extract implicit priorities, helping reduce friction between parties.

Coming features include a smart pricing tool that evaluates project complexity, historical behaviour, and market rates to suggest budgets and fees—improving quote accuracy on both sides.

According to founder and CEO Huang Guohua, EPWK will double down on its core operations while expanding AI integration. This includes enhancing the “EPWK AI Assistant” to improve task matching, streamline user experience, and explore applications in AIGC-driven content generation. The aim is to build defensible technology infrastructure that boosts platform efficiency, user retention, and transaction volume.

The company also plans to expand into higher-value services beyond design and development—such as marketing, AI solutions, and full-cycle brand management. These verticals are expected to drive up average transaction value and profit margins, helping to diversify and strengthen the company’s revenue model.

Global Rollout Targets Southeast Asia, Japan, and the West

With the launch of its international version, EPWK is officially scaling its cross-border infrastructure. The company—among the first Chinese creative platforms to list in the US via a VIE structure—aims to tap overseas creative labor pools while helping Chinese SMEs expand internationally.

Global expansion has become a strategic priority for EPWK following its listing on Nasdaq. The company plans to localise operations in key growth markets—particularly Europe, North America, and Southeast Asia—by offering multilingual support and region-specific services. The goal is to tap into strong demand for creative services, build new growth channels, and strengthen the company’s brand presence abroad.

EPWK is also focused on building a global network by partnering with local businesses and institutions to attract international buyers and sellers. This approach aims to accelerate market integration and expand the platform’s ecosystem.

Ultimately, EPWK positions itself as a global engine linking creative talent with business demand—an AI-powered marketplace for digital services, mirroring what Alibaba built for physical goods.

Frost & Sullivan estimates that China’s creative crowdsourcing market could reach $24.3 billion by 2028. With scale, tech infrastructure, and international momentum, EPWK is positioning itself to lead that transformation.

Looking Ahead: Building a Global Creative Services Ecosystem

According to Frost & Sullivan, China’s creative crowdsourcing market is projected to reach $24.3 billion by 2028. With its strong market position, solid technical foundation, and expanding international footprint, EPWK aims to further optimise its platform capabilities and user experience, while strengthening IP protection mechanisms. The company’s long-term goal is to provide SMEs, creative professionals, and global buyers with a reliable and efficient service infrastructure—bringing China’s crowdsourcing model to the global stage and establishing a creative services marketplace with international influence.

CEO Huang Guohua notes that EPWK will continue to drive innovation through data and emerging technologies. By leveraging platform data to fine-tune its algorithms, the company intends to deliver more accurate task matching and market trend predictions, increasing matching efficiency and extracting greater value from its data assets. EPWK is also exploring blockchain applications for transaction security and copyright verification, and investigating virtual workspaces in the metaverse as future service environments.

To reinforce its ecosystem, the company plans to activate stronger network effects through incentive policies and high-quality service delivery—attracting more buyers and sellers and amplifying its two-sided marketplace dynamics. In parallel, it will roll out value-added services such as skills training and SaaS tools for service providers, boosting retention and unlocking new revenue streams.

EPWK also positions social responsibility as part of its long-term strategy. By providing technical support and connecting resources, the company aims to help SMEs undergo digital transformation and contribute to the broader growth of the creative economy. Through its global platform, EPWK seeks to connect creative talent across borders and deliver greater value to users worldwide.

About EPWK:

EPWK is operated by Xiamen EPWK Network Technology Co., Ltd., a national high-tech enterprise in China and a Nasdaq-listed company (EPWK) as of February 6, 2025. It has 179 tech achievements (including 137 software copyrights) and 17 patent applications (9 granted). The company is recognized as a leader in digital crowdsourcing infrastructure and a key player in China’s creative economy.

As the first China-based digital creative services marketplace to go public in the U.S., EPWK is widely regarded as the country’s pioneering crowdsourcing platform. Looking ahead, the company plans to evolve beyond a transactional marketplace into a monetisation-driven ecosystem—enabling users not just to connect, but to convert skills and creativity into scalable value.

EPWK envisions a global creative value chain that spans design, production, and distribution. The long-term strategy is to build a hybrid platform that integrates virtual services with physical products, bridges online and offline workflows, and links domestic demand with international markets. By combining platform economics with ecosystem incubation, EPWK aims to establish itself as a next-generation internet enterprise—one that not only facilitates transactions but actively drives value creation across the creative economy.

DXC Named a Leader by IDC MarketScape in Industrial IoT End-to-End Engineering and Lifecycle Services

ASHBURN, Va., Aug. 28, 2025 /PRNewswire/ — DXC Technology (NYSE: DXC), a leading Fortune 500 global technology services provider, has been named a Leader in the “IDC MarketScape: Worldwide Industrial IoT End-to-End Engineering and Life-Cycle Services 2025 Vendor Assessment*.” The recognition highlights DXC’s Industrial IoT services to enhance operations and provide greater visibility into the supply chain for industries that rely heavily on physical assets like property, machinery, and equipment.

DXC Named a Leader by IDC MarketScape in Industrial IoT End-to-End Engineering and Lifecycle Services
DXC Named a Leader by IDC MarketScape in Industrial IoT End-to-End Engineering and Lifecycle Services

“To help our customers unlock the full potential of Industrial IoT, we combine deep industry expertise, digital twin technology, and IoT which creates a more comprehensive capability around simulation, process engineering, and recovery,” said Pete McEvoy, Head of Data and AI at DXC. “We believe this recognition by the IDC MarketScape highlights our industry expertise and value as a trusted partner, delivering measurable business outcomes as our clients navigate their digital transformation journey.”

DXC delivers IIoT services using a consistent approach that was designed by its industry experts, delivering the following benefits across manufacturing:

  • Asset Management: Lower maintenance costs and optimize production and scheduling.
  • Incident Mitigation: Rapidly detect, assess, and resolve failures, quality issues, or disruptions across manufacturing, supply chains, and asset-intensive operations.
  • Quality Control: Minimize waste, defects, and rework by identifying product or supply chain issues early and triggering near real-time alerts through custom apps and interfaces.
  • ESG Compliance: Gain real-time visibility into energy use, analyze consumption and pricing trends, boost efficiency, reduce energy costs, and prevent waste.

“IDC Identifies DXC’s strength as its comprehensive Industrial IoT solutions and services portfolio, proprietary frameworks for IIoT and Industry 4.0 solutions and services and delivery ecosystem. DXC’s clients highly appreciate its focus on meeting the business KPIs, proactiveness in bringing new Industrial IoT and Industry 4.0 use cases and showcasing of ROI implications upfront. Its onshore and nearshore heavy model further resonates well with its customers in terms of delivery effectiveness and efficiency. DXC’s investments in R&D, partnerships and extending its delivery ecosystems to other high growth markets are expected to bolster its position in the market and confidence amongst its clients,” said Abhishek Mukherjee, Research Manager, Digital Engineering and Operational Technology Services at IDC.     

DXC helps enterprises design, deploy and manage secure, scalable Industrial IoT and digital twin solutions, powering smart factories, connected operations, and advanced public services such as healthcare, traffic management, and aerospace and defense. Our strategies have delivered maintenance cost savings across fleets, equipment, and machines, and ROI through improved production visibility and quality in manufacturing and supply chain.

This first IDC MarketScape for IIoT end-to-end engineering and life-cycle services evaluated 15 vendors. This evaluation provides a combined view of these service providers’ capabilities in IIoT strategy/consulting, systems integration, engineering, and managed services. 

An excerpt of the IDC MarketScape report and more information on its methodology is available to view here. To learn more about DXC’s IIoT and Digital Twin Services, click here. More information on DXC’s expertise in the manufacturing sector can be found here.

About IDC MarketScape:  
IDC MarketScape vendor assessment model is designed to provide an overview of the competitive fitness of technology and service suppliers in a given market. The research utilizes a rigorous scoring methodology based on both qualitative and quantitative criteria that results in a single graphical illustration of each supplier’s position within a given market. IDC MarketScape provides a clear framework in which the product and service offerings, capabilities and strategies, and current and future market success factors of technology suppliers can be meaningfully compared. The framework also provides technology buyers with a 360-degree assessment of the strengths and weaknesses of current and prospective suppliers. 

About DXC Technology
DXC Technology (NYSE: DXC) is a leading global provider of information technology services. We’re a trusted operating partner to many of the world’s most innovative organizations, building solutions that move industries and companies forward. Our engineering, consulting and technology experts help clients simplify, optimize and modernize their systems and processes, manage their most critical workloads, integrate AI-powered intelligence into their operations, and put security and trust at the forefront. Learn more on dxc.com.

* Doc # US51812924, August 2025

Angelena Abate, Media Relations, +1.646.234.8060, angelena.abate@dxc.com

D3 Bio, Inc. Announces FDA Breakthrough Therapy Designation and Orphan Drug Designation for D3S-001 for the Treatment of Patients with KRAS G12C-Mutated Cancers

  • Breakthrough Therapy Designation was granted for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) who have had prior treatment with platinum-based chemotherapy and anti-PD-(L)1 antibody but have not been previously treated with a KRAS G12C inhibitor
  • Orphan Drug Designation was granted for treatment of colorectal cancer (CRC) harboring KRAS G12C mutant protein.

SHANGHAI, Aug. 28, 2025 /PRNewswire/ — D3 Bio, Inc, a clinical-stage oncology company focuses on discovery and development of precision oncology therapies, today announced that the U.S. Food and Drug Administration (FDA) has granted a Breakthrough Therapy Designation to D3S-001, the company’s next generation KRAS G12C-selective inhibitor, for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic NSCLC who have received prior chemotherapy and immunotherapy but have not been previously treated with a KRAS G12C inhibitor. Additionally, D3S-001 has been granted Orphan Drug Designation for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic CRC.

The Breakthrough Therapy and Orphan Drug Designations are based on clinical data from an ongoing Phase 1/2 study (NCT05410145) evaluating D3S-001 in patients with advanced solid tumors harboring a KRAS G12C mutation. Results from this ongoing clinical trial demonstrated highly compelling and durable efficacy according to RECIST (Response Evaluation Criteria in Solid Tumors) with a favorable safety and tolerability profile.

We are very pleased to receive both Breakthrough Therapy and Orphan Drug Designations from the FDA for D3S-001, which highlights D3S-001’s promising potential to address critical unmet needs in patients with KRAS G12C-mutated cancers,” said George Chen, Founder and CEO of D3 Bio. “These designations also recognize D3S-001’s novel profile as a next-generation KRAS G12C inhibitor. We look forward to bringing this exciting new treatment to patients with support and collaboration from health authorities.”

KRAS mutations are among the most common oncogenic drivers in human cancers, found in approximately 25 to 30% of all tumors. The KRAS G12C mutation occurs in approximately 12% of NSCLC cases and 3 to 4% of CRC. Patients with KRAS G12C-mutated cancers often have more aggressive disease and limited responses to standard therapies, such as immunotherapy and/or chemotherapy.

About D3S-001

D3S-001 is a next-generation KRAS G12C inhibitor designed to achieve rapid and complete KRAS G12C target engagement. D3S-001 potently, selectively, and covalently binds to the oncogenic RAS (Off) form of the RAS G12C variant, functionally abolishing the nucleotide cycling between RAS (Off) and RAS (On) forms of the G12C mutant protein. In preclinical investigations, D3S-001 demonstrated high covalent potency, complete engagement of KRAS G12C at clinically relevant doses and CNS penetration properties. D3S-001 is currently under evaluation as monotherapy and in combination regimens in a Phase II global clinical trial in patients with advanced solid tumors harboring KRAS G12C mutations, including NSCLC, CRC, and other tumor types. Key publications:

  • D3S-001, a KRAS G12C Inhibitor with Rapid Target Engagement Kinetics, Overcomes Nucleotide Cycling, and Demonstrates Robust Preclinical and Clinical Activities. Cancer Discov. (2024)14 (9):1675–1698.
  • D3S-001 in advanced solid tumors with KRASG12C mutations: a phase 1 trial. Nat Med. 2025 Aug;31(8):2768-2777.

About D3 Bio

D3 Bio is a global biotechnology company focused on the discovery, development, and registration of new medicines in oncology and immunology. The company’s discovery and development platforms leverage proprietary clinical insight and biomarker strategies to create novel and clinically meaningful therapies for patients in need. D3 Bio’s oncology programs target driver mutations or critical immune pathways and are designed to have first-in-class or best-in-class potential. D3 Bio owns global rights for all of its programs. For more information, please visit www.d3bio.com.

Contacts

Media Contact:
Rui Liu
Head, Corporate Affairs
bd@d3bio.com

Binance Execution Services Now Aggregates OTC Liquidity for Tighter Spreads and Faster Execution

Institutional users can choose between instant spot and options OTC and fully-managed bespoke execution to meet their needs

DUBAI, UAE, Aug. 28, 2025 /PRNewswire/ — Binance, the world’s largest cryptocurrency exchange by trading volume and users, today announced it has upgraded its Execution Services to aggregate spot and options liquidity from an extensive network of liquidity providers, in addition to the exchange’s deep and proprietary native order books. The new approach prioritizes flow internalization, helping large-volume users improve speed, price performance, and execution time. Depending on their requirements, users can choose between OTC risk-pricing, and bespoke execution whereby the execution desk will leverage Binance’s algorithmic capabilities and market leading liquidity.

Binance supports two primary types of algorithmic trading, Time Weighted Average Price (TWAP) and Percentage of Volume (POV), and users can directly manage their own algorithmic trade through the Binance VIP Portal as well as request for Binance VIP assistance in running their trading where they can specify certain instructions.

As with traditional finance, over-the-counter or OTC trading lets users secure risk-pricing for large transactions to minimize slippage and avoid impacting the market, especially for illiquid assets. Binance will aggregate and submit the most competitive live OTC quotes when users initiate a request, and the trade can settle in as little as 15 minutes, a significant improvement over the industry standard of T+1. Users also have the flexibility of choosing a longer settlement window to fit their liquidity needs.

Binance Execution Services appeals to a wide range of institutional and sophisticated users, including:

  • Large-volume traders: users can lock in pricing for large-volume trades to minimize slippage they otherwise can encounter when trading on the order book
  • Long-time holders and less active “whales”: long-time holders with infrequent trading experience can find it more convenient and efficient to outsource execution
  • Mid-sized entities: market participants such as mid-sized hedge firms can utilize OTC trading to complement their trading strategies and better compete
  • High-frequency trading firms: participants that transact in high frequency trading can opt to become liquidity providers and leverage their very high volume requirements

“Clients who prioritize pricing and speed for larger trades will enjoy our enhanced OTC service, and clients who prefer bespoke execution can also rely on us to fully manage the process for them. By tailoring solutions for the different segments, we help sophisticated clients from high-net-worth individuals and family offices to larger institutions optimize their crypto experience,” commented Catherine Chen, Head of VIP & Institutional at Binance.

The number of VIP and institutional users on Binance grew by 21% and 20% respectively in H1/2025 as compared to H1/2024. Trading volume for the two categories grew by 10% and 12% respectively for the same period.

“We are enhancing our execution capabilities alongside our other offerings to ensure we continue to be well-positioned to support our institutional clients’ growing demand for exposure to crypto,” added Chen.

Institutional users can explore how Binance can enhance their trading experience by visiting Binance Execution Services or contacting Binance VIP & Institutional here.

Disclaimer: The products and services referred to herein may be restricted in certain jurisdictions or regions or to certain users, in accordance with applicable legal and regulatory requirements. These materials are intended only for those users who are permitted to access and receive the products and services referred to and are not intended for users to whom restrictions apply. Digital asset prices are subject to high market risk and price volatility. The value of your investment may go down or up, and you may not get back the amount invested. You are solely responsible for your investment decisions and Binance is not liable for any losses you may incur. Past performance is not a reliable predictor of future performance. You should only invest in products you are familiar with and where you understand the risks. You should carefully consider your investment experience, financial situation, investment objectives and risk tolerance and consult an independent financial adviser prior to making any investment. This material should not be construed as financial advice. For more information, see our Terms of Use and Risk Warning.

About Binance

Binance is a leading global blockchain ecosystem behind the world’s largest cryptocurrency exchange by trading volume and registered users. Binance is trusted by more than 280 million people in 100+ countries for its industry-leading security, transparency, trading engine speed, protections for investors, and unmatched portfolio of digital asset products and offerings from trading and finance to education, research, social good, payments, institutional services, and Web3 features. Binance is devoted to building an inclusive crypto ecosystem to increase the freedom of money and financial access for people around the world with crypto as the fundamental means.

For more information, visit: https://www.binance.com 

About Binance VIP & Institutional

Binance VIP & Institutional empowers institutions and private wealth clients with robust asset management infrastructure, personalized VIP services and advanced end-to-end institutional trading tools on the world’s largest cryptocurrency exchange by trading volume and registered users. With deep financial services experience in both traditional and crypto markets, its global team of trusted experts provides VIP & Institutional clients with the support they need to confidently capitalize on the industry’s deepest liquidity and tightest markets.

For more information, visit: https://www.binanceinstitutional.com

IMG Shares 2025 Autumn Travel Trends: Top Destinations and Increased Spending

  • IMG took a sample of its customers and reviewed more than 30,000 travel itineraries of members with upcoming travel plans between September 1st and November 30th of 2025 to determine emerging travel trends this autumn.

INDIANAPOLIS, Aug. 28, 2025 /PRNewswire/ — IMG (International Medical Group) has conducted a review of customers’ travel plans from the beginning of September to the end of November and predicts this autumn’s top 5 international destinations for U.S. travelers to be:

  1. Mexico – top country 3 years in a row
  2. Italy
  3. United Kingdom
  4. Canada
  5. Spain

IMG data shows a 13% increase in the average insured trip cost among IMG travelers this autumn compared to the same time period in 2024, and those planning to travel this season will be taking trips averaging 11 days in length, which is two days longer than the average for autumn 2024 travelers.

With longer trips and more money invested in their travels, more travelers want to make sure their trip investment is protected. IMG has seen more than a 50% increase in travel protection plan purchases among travelers this autumn compared to last autumn.

“As travelers plan longer and more expensive trips this autumn, we’re seeing a clear shift toward prioritizing protection and peace of mind,” said Justin Poehler, IMG Chief Commercial Officer. “With the increase in travel protection plan purchases, it’s evident that travelers are taking a more thoughtful approach to planning their experiences abroad.”

To learn more about IMG’s award-winning travel and health safety solutions, please visit www.imglobal.com.

About IMG® (International Medical Group®)
IMG® (International Medical Group®), a SiriusPoint company, is an award-winning global insurance benefits and assistance services company that has served millions of members worldwide since its founding in 1990. The preeminent provider of travel and health safety solutions, IMG offers a wide range of insurance programs, including international private medical insurance, travel medical insurance, and travel insurance, as well as enterprise services, including insurance administrative services and 24/7 emergency medical, security, and travel assistance. IMG’s world-class services, combined with an extensive product portfolio, provide Global Peace of Mind® for travelers, students, missionaries, marine crews, and other individuals or groups traveling, working, or living away from home. For more information, please visit www.imglobal.com.

Media Contact: Carly Kessler, IMG Communications Manager, carly.kessler@imglobal.com