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Polyplastics Launches New Eco-friendly PLASTRON (R) ︎LFT with Reduced Weight, Higher Rigidity, and Strong Damping

TOKYO, Feb. 13, 2025 /PRNewswire/ — Polyplastics Co., Ltd., a global leader in engineering plastics, has launched PLASTRON (R) LFT (long fiber-reinforced thermoplastic) RA627P, an eco-friendly composite of polypropylene (PP) resin and long cellulose fiber which delivers low density, high specific rigidity, high impact strength, and excellent damping for a range of applications, including audio components (speaker diaphragms) and housings of industrial components.

Image 1: https://cdn.kyodonewsprwire.jp/prwfile/release/M100475/202502043779/_prw_PI1fl_4W1kxGBW.png

Image 2: https://cdn.kyodonewsprwire.jp/prwfile/release/M100475/202502043779/_prw_PI3fl_3xCP5TL4.jpg

The development of PLASTRON (R) LFT RA627P reinforces Polyplastics’ commitment to reduce the environmental impact of its materials and bring about a sustainable society. Thanks to its regenerated cellulose fiber content, PLASTRON (R) RA627P boasts a reduced carbon footprint — roughly 30% less than that of 30% short glass fiber-reinforced PP resin. The new LFT is a composite of PP resin and uninterrupted 30% long cellulose fiber of the same length which is oriented in the same direction. The regenerated cellulose fiber exhibits high strength and elasticity thanks to unique spinning conditions and polymerization of the raw cellulose materials.

PLASTRON (R) RA627P provides roughly 10% lower density than 30% short glass fiber- reinforced PP resin, while maintaining roughly the same flexural modulus. The material also has a specific rigidity level that is higher than that of 30% short glass fiber-reinforced PP resin, with a large loss coefficient at the same time.

The properties of high specific rigidity and large loss coefficient typically have an inverse relationship, but PLASTRON (R) RA627P offers an excellent balance of these properties, making it suited for audio equipment components such as speaker diaphragms which require this balance.

Image 3: https://cdn.kyodonewsprwire.jp/prwfile/release/M100475/202502043779/_prw_PI2fl_9aV2sDpg.png

Image 4: https://cdn.kyodonewsprwire.jp/prwfile/release/M100475/202502043779/_prw_PI4fl_PQ6XXkm7.png

Polyplastics is developing new grades made from recycled PP resin that can further mitigate carbon footprint levels while also expanding its portfolio of PLASTRON (R) LFT products to meet growing market needs.

For more information, visit: https://www.polyplastics-global.com/en/approach/35.html

About Polyplastics: https://kyodonewsprwire.jp/attach/202502043779-O1-f3kx6N6F.pdf

PLASTRON (R) is a registered trademark of Polyplastics Co., Ltd. in Japan and other countries.

Fujitsu to offer Fujitsu Cloud Service Generative AI Platform for secure and flexible enterprise data management

KAWASAKI, Japan, Feb. 13, 2025 /PRNewswire/ — Fujitsu today announced the launch of the Fujitsu Cloud Service Generative AI Platform. The new service, which combines data confidentiality with the ease of use of the cloud, will be made available in Japan during fiscal year 2025, with a global rollout planned for the future. Fujitsu will begin accepting applications for a trial of this service in Japan starting February 13, 2025.

Generative AI offers significant productivity gains across various business functions from brainstorming and meeting minute generation to automated code creation. However, its adoption in sectors handling sensitive data has been limited due to concerns about data leakage, unintended AI learning, and compliance with internal regulations. Fujitsu’s new platform directly addresses these challenges.

To ensure data security and compliance, the service combines Fsas Technologies Inc.’s Private AI Platform on PRIMERGY, Supermicro’s GPU servers, and Fujitsu’s Takane large language model (LLM) which is the core technology of the Fujitsu Kozuchi AI service and renowned for its world-leading Japanese language capabilities, as well as generative AI security enhancement technologies to offer an on-demand cloud-based generative AI solution through Fujitsu’s data centers. This architecture manages client data in a private area on the cloud in Fujitsu’s data center, allowing for the secure processing of confidential information.

In addition to Takane, Fujitsu plans to gradually increase the number of available LLMs from other companies to meet customer needs.

Fujitsu will add the new service to its Fujitsu Computing as a Service (1) portfolio. Fujitsu will provide comprehensive support, from initial implementation to ongoing optimization, enabling businesses to maximize the efficiency and productivity gains of generative AI and drive significant business transformation.

For full release click here

CRIMSONLOGIC AND BDO SINGAPORE SIGN STRATEGIC PARTNERSHIP TO DEVELOP SPECIALIZED GENERATIVE AI ADVISORY PLATFORM

This strategic partnership aims to transform professional advisory services by leveraging cutting-edge Generative AI to provide accurate, domain-specific insights

SINGAPORE, Feb. 13, 2025 /PRNewswire/ — Global technology company CrimsonLogic, a wholly-owned subsidiary of PSA International and a leader in digital trade, digital ports, and technology solutions, is expanding its proprietary Generative AI (GenAI) advisory platform “AskCL”, through a strategic collaboration with BDO Singapore, a leading professional services firm. Together, they are co-creating “AskBDO” – an innovative Generative AI (GenAI) advisory platform designed to provide accurate, domain-specific insights for professionals in legal, tax, and finance.

Currently, GenAI solutions commonly encounter issues such as hallucination, where AI generates plausible but incorrect information, as well as data lineage inconsistencies, contextual limitations, data freshness, privacy concerns, and ethical considerations. These are critical areas that any robust GenAI solution must address to be effective and trustworthy.

“AskBDO” combines CrimsonLogic’s technological expertise with BDO’s domain-specific insights to deliver accurate, reliable, and relevant responses to specialized queries, providing users with a dedicated virtual advisor to access precise information quickly, thereby enhancing their decision-making processes and reducing the risk of errors. This improved efficiency allows these professionals in specialized fields such as legal, tax, and finance to focus on complex tasks that require human expertise, ultimately delivering greater value to their clients and organizations.

The “AskBDO” platform leverages updated, curated knowledge bases and fine-tunes solutions for specific industries to provide verifiable responses. It also allows multiple organizations to use the platform while keeping their data isolated and secure, as its multi-universe knowledge base separates and manages both public and private data, enhancing the contextual accuracy of responses. Additionally, the platform offers robust customization capabilities, empowering users to develop tailored topics and knowledge bases.

“This strategic partnership with BDO Singapore represents a significant milestone in our commitment to revolutionize professional advisory services through advanced technology. Together, we are not just developing a tool, but shaping the future of how businesses leverage AI for strategic decision-making and operational excellence,” said Lawrence Ng, CEO of CrimsonLogic.

Frankie Chia, Managing Partner at BDO Singapore, said, “This collaboration with CrimsonLogic enables us to innovate and leverage cutting-edge technology to deliver practical, tailored solutions for our clients. “AskBDO” will empower our professionals with enhanced access to specialized knowledge and domain expertise, acting as a valuable resource that supports their day-to-day work. Looking ahead, we also aim to offer our clients the opportunity to experience a Digital BDO, providing them with faster, more accurate insights and greater value through innovative, AI-driven solutions.”

Together, CrimsonLogic and BDO Singapore mark a transformative leap in the adoption of GenAI across industries, setting a new benchmark for professional advisory services in the digital age.

ABOUT CRIMSONLOGIC

CrimsonLogic, a wholly-owned subsidiary of PSA International, is a global technology company driven by innovation to digitally transform and simplify global trade. With over 36 years of experience worldwide, CrimsonLogic specializes in technology enablement in the fields of trade facilitation and compliance, port operations, government services and logistics. As a trusted partner to businesses, logistics service providers and governments, their tailored solutions are designed to meet the unique needs of every client, enabling seamless and secure optimization of supply chains and operations. Having pioneered the world’s first single window trade facilitation system for Singapore, CrimsonLogic continues to drive digital transformation in global trade via cutting-edge technology, exemplified by the successful implementation of innovation solutions in over 40 countries worldwide.

ABOUT BDO SINGAPORE

BDO Singapore is a leading professional services firm offering audit, tax, and advisory solutions to SMEs, large private businesses, and multinational corporations. Established in 1972, we have built a strong reputation with a team of over 600 professionals delivering services such as Audit & Assurance, Tax & Risk Advisory, Business Restructuring & Forensics, Deal, Cyber Security & Digital Advisory, Management Consulting and Outsourced Accounting.

As an independent member of BDO International, the world’s fifth-largest professional services network with a presence in 166 countries — they provide global expertise with local insights. BDO’s partners and directors foster trust and innovation, helping clients grow and transform in a culture of collaboration and excellence.

Bad Data Makes Bad Decisions: 65% of Asia-Pacific Leaders Report Companies Using Inaccurate Data for Big Decisions

On average, APAC leaders are struggling more with data management issues compared to North America/EMEA counterparts, according to global study from SoftServe

SINGAPORE, Feb. 13, 2025 /PRNewswire/ — SoftServe, a premier IT consulting and digital services provider, has released survey results on the state of data management in 2025, unveiling significant benefits of strong data foundations while exposing the widespread deficits in data maturity affecting most businesses. Majority of the 250 business leaders surveyed in Asia-Pacific (APAC) barely grasp the value of their data as 77% of all APAC respondents believe no one at their organization understands all the data collected and how to access it. Further, 65% say key business decisions are based on inaccurate or inconsistent data – most of the time, if not always – raising concerns for companies across industries and borders. Both percentages are higher than the global average of 65% and 58%, respectively.

This study, commissioned by SoftServe and conducted by Wakefield Research, assesses data readiness in enterprises by the degree of data quality, strategy, organization, investment, and governance implemented. Responses indicate a lack of knowledge in data management is coupled with an internal disconnect and noticeable divide between the C-suite, VPs, and senior management, putting entire organizations at odds when it comes to how data is used, acquired, and funded.

Key survey findings include:

  • Outdated or Misaligned Strategies: Many think it’s time to hit ‘refresh’ on their data strategy as 78% report major updates or a complete overhaul is needed, and nearly all (99%) believe an updated data strategy would be required for strategic initiatives like Gen AI.
  • Leadership Impact: Less visibility among APAC leaders can lead to skewed perceptions of data usage and comprehension, with 69% of C-suite and 66% of VPs and directors claiming their organization’s investment priorities are negatively impacted by leaders not fully understanding how data can generate value. Factors like varied tech solutions used throughout their organization (58%) and non-consolidated data ownership (44%) are the top challenges C-suite leaders face while trying to improve their data strategy.
  • Data on Demand: For 66%, decision-makers getting access to data when they need it is a challenge – and one that may not be an easy fix, as more than half (52%) of the 65% whose organization makes most or all decisions using inaccurate or inconsistent data now believe a significant increase in data management investment is needed to meet their goals.
  • Misallocated Investments: 8 in 10 (80%) APAC business leaders believe poor prioritization has diverted needed funds and talent away from valuable data projects to broad Gen AI initiatives with weaker ROI.

All deficits aside, the survey results include a silver lining: strong data management has allowed organizations to open new revenue streams (43%) or monetize their data (35%) with the right infrastructure and governance to transform information into a vital source of income. Organizations also attributed increases in productivity and efficiency (55%), as well as improved decision-making and forecasting abilities (43%), to having strong data foundations. Most respondents hope to follow suit this year as the bulk (92%) prepare to slightly or significantly increase their data budget and over half (51%) of those with a fully mature data strategy expect to significantly increase their overall data investments.

“Digitally transformative, data-driven technologies like AI are developing rapidly in the APAC region, and what this means is that an updated data strategy will be key,” said Wells Vaughan,  APAC Chief Technology Officer at SoftServe. “Business leaders need to make sure they are not pursuing technology innovation at the expense of a mature, agile data foundation, which will help them maximize return on investments for emerging technology projects and provide them with a competitive edge.”

Out of 750 total business or technology leaders surveyed across eight countries, 250 respondents were from the APAC region. All participants were responsible for data management or AI use at global companies with $1 billion or more in annual revenue throughout eight different industries. See the full demographic breakdown and explore even more data in SoftServe’s comprehensive report on the data divide at this link.

ABOUT SOFTSERVE

SoftServe is a premier IT consulting and digital services provider. We expand the horizon of new technologies to solve today’s complex business challenges and achieve meaningful outcomes for our clients. Our boundless curiosity drives us to explore and reimagine the art of the possible. Clients confidently rely on SoftServe to architect and execute mature and innovative capabilities, such as digital engineering, data and analytics, cloud, and AI/ML.

Our global reputation is gained from more than 30 years of experience delivering superior digital solutions at exceptional speed by top-tier engineering talent to enterprise industries, including high tech, financial services, healthcare, life sciences, retail, energy, and manufacturing. Visit our websiteblogLinkedInFacebook, and X (Twitter) pages for more information.

Webull Masters 2025 Kicks Off: an Exciting Stock Trading Competition in Thailand with Over THB170,000 in Prizes

BANGKOK, Feb. 13, 2025 /PRNewswire/ — Webull Securities (Thailand) Co. Ltd. (“Webull Thailand”), the Thai subsidiary of Webull Corporation (“Webull”), a leading global digital investment platform, has officially announced the launch of the Webull Masters 2025 trading competition for its users in Thailand. This marks Webull Thailand’s inaugural live trading competition, which began on February 10 and will run through March 9, 2025.

The competition will take place over multiple rounds, with participants competing in five events for a chance to win generous rewards and demonstrate their investment skills. Rankings will be determined by participants’ return on investment, with weekly leaderboards published at the end of each week. The top three participants with the highest returns each week will be awarded trading vouchers valued at THB 5,000, THB 3,000, and THB 1,000, respectively. At the end of the competition, the top ten participants on the monthly leaderboard will receive prizes, with the first-place winner taking home a trading voucher worth up to THB 50,000, along with a trophy. The total prize pool for the competition exceeds THB 170,000.


Chonladet Khemarattana, CEO of Webull Thailand, commented, “Thai investors have shown a strong enthusiasm for US stock trading, which inspired us to organize this trading competition. We are encouraged by the love Thai investors have shown for Webull, as we now have over 300,000 registered users. The competition provides an excellent platform for participants to showcase their skills and learn from others. Additionally, we will be promoting investment knowledge during the competition by requiring participants to watch an introductory video, helping them enhance their trading skills.”

Since entering the Thai market last year, Webull has continually optimized its products and services, achieving rapid growth. Earlier this year, Webull was honored with the title of Best Trading Platform for US Stocks by The Global Economics Awards 2024, further validating Webull’s commitment to providing investors with a leading trading platform.

For more details and to participate in the competition, please visit the Webull App, official website, or social media platforms.

About Webull:

Webull is a leading digital investment platform built on next generation global infrastructure. The Webull Group operates in 15 regions globally and is backed by private equity investors located in the United States, Europe and Asia. Webull serves more than 20 million registered users globally, providing retail investors with 24/7 access to global financial markets. Users can put investment strategies to work by trading global stocks, ETFs, options, futures and fractional shares through Webull’s trading platform, which seamlessly integrates market data and information, its user community, and investor education resources. Learn more at https://www.webullcorp.com/.

MEDIA CONTACTS
Webull Securities (Thailand) Co. Ltd.
Email: marketing@webull.co.th 
Telephone number: +66 (0) 2026 5222

Schwab Makes Expanded 24-Hour Trading Available to All Clients

Overnight trading of all S&P 500®, Nasdaq-100® stocks and hundreds of ETFs is now available to all Schwab clients via the thinkorswim® platform suite

 Hong Kong was Fifth Highest Source of Overnight Trading Activity in Pilot Period

HONG KONG, Feb. 13, 2025 /PRNewswire/ — Charles Schwab, a leader in investing and trading with US$10.10 trillion in total client assets that facilitates approximately six million daily average trades, today announced the launch of broad access to an expanded range of securities in the overnight trading session following a series of successful pilots at the end of 2024. Now, all Schwab clients can trade an expanded list of securities including the S&P 500 and Nasdaq-100 stocks and hundreds of additional exchange-traded funds (ETFs) 24 hours a day, five days a week (24/5), via the thinkorswim platform suite.

Ameritrade, which was acquired by Schwab in 2020, pioneered 24/5 trading in 2018 as the first U.S. retail broker-dealer to make it available to traders, offering approximately two dozen ETFs in the overnight trading session. Schwab began piloting expanded overnight access with a small group of clients in November 2024 and has gradually expanded the reach in the intervening months in preparation for broad availability. During the pilot period, Hong Kong was the fifth most popular region to engage in overnight trading, following markets such as the U.S., Mainland China and Taiwan.

“We are proud to have a long legacy as overnight trading pioneers and that we continue to evolve and enhance our capabilities and platforms today,” said Isabella Chan, Director, Business Development, at Charles Schwab Hong Kong. “Schwab facilitates about two times the trades each day of any competitor that reports that figure publicly, so we know that it’s a significant milestone not just for Schwab but for our industry as we expand access to overnight trading to our millions of clients. We have worked hard to combine the power of our world-class trading platforms, specialized 24-hour service and support, and tailored education to deliver a trading experience that balances the unique dynamics and potential risks of the overnight session while empowering clients to trade in the ways and during the hours that, particularly for our clients in Asia, may suit them and their lifestyle best.”

Insights from Schwab’s recent 24/5 expansion pilot

During the expanded 24/5 pilot period, which ran from November 2024 through January 2025 beginning with a small group of clients and grew in phases, the most active trading hours of the overnight session were the first and last, between 8-9pm ET and 3-4am ET. The stocks Schwab clients most actively bought, sold, or both during the overnight session pilot were:

  • Tesla Inc. (TSLA)
  • NVIDIA Corp. (NVDA)
  • Palantir Technologies Inc. (PLTR)
  • MicroStrategy Inc. (MSTR)
  • Advanced Micro Devices (AMD)

Schwab clients may access expanded 24/5 trading by selecting the EXTO order type for eligible securities on the thinkorswim trading platforms. Visit our website to learn more about trading platforms at Schwab.

Disclosures

Investing involves risk, including, for some products, more than your initial investment.

Extended-Hours Trading Information

  • Please note that the commissions for trades executed in multiple sessions (i.e., pre-market, regular or after hours) are not aggregated. Extended hours trades will normally settle one business day from the date the order is executed, just like orders placed during regular market hours. Orders placed after 8:05 p.m. ET are eligible for execution once the next Pre-market session opens at 7:00 a.m. ET.
  • Extended Hours Trading may not be suitable for all investors and poses certain risks. These risks include, but are not limited to, lower liquidity, higher volatility, price changes between regular and extended hours market sessions, unlinked markets, news announcements, and wider spreads. To learn more call +852-2101-0511.
  • Due to limited liquidity in Extended Hours Trading sessions, there are no assurances that an investor’s stock order will be executed.
  • Extended Hours Trading will not take place on official Exchange holidays or when Exchanges close early. Schwab reserves the right to change or modify hours of operation for Extended Hours Trading at any time. A Schwab Extended Hours Trading session, or any security traded therein, may be temporarily or permanently suspended at our discretion.

The information provided here is for general informational purposes only and should not be considered an individualized recommendation or personalized investment advice. All expressions of opinion are subject to changes without notice in reaction to shifting market, economic, and geopolitical conditions.

Data herein is obtained from what are considered reliable sources; however, its accuracy, completeness, or reliability cannot be guaranteed. Supporting documentation for any claims or statistical information is available upon request.

ETFs can entail risks similar to direct stock ownership, including market, liquidity, tracking errors, sector, or industry risks. Some ETFs e.g. synthetic ETFs and leveraged inverse may involve emerging market, passive investment, tax, currency, commodity, leverage, credit and interest rate risk. Trading prices may not reflect the net asset value of the underlying securities.

All corporate names and market data shown above are for illustrative purposes only and are not a recommendation, offer to sell, or a solicitation of an offer to buy any security. Supporting documentation for any claims or statistical information is available upon request.

This material is published by Charles Schwab, Hong Kong, Ltd. and has not been reviewed by the Securities & Futures Commission of Hong Kong (SFC).

Charles Schwab, Hong Kong, Ltd. is an affiliate of Charles Schwab & Co., Inc. Nothing here is an offer or solicitation of these securities, products and services by Charles Schwab, Hong Kong, Ltd. and Charles Schwab & Co., Inc. in any jurisdiction where their offer or sale is not qualified or exempt from registration.

©2025 Charles Schwab, Hong Kong, Limited. Room 3401, Gloucester Tower, The Landmark, 15 Queen’s Road Central, Central, Hong Kong. All rights reserved.

About Charles Schwab

At Charles Schwab, we believe in the power of investing to help individuals create a better tomorrow. We have a history of challenging the status quo in our industry, innovating in ways that benefit investors and the advisors and employers who serve them, and championing our clients’ goals with passion and integrity.

More information is available at aboutschwab.com. Follow us on X, Facebook, YouTube, and LinkedIn.

About Charles Schwab Hong Kong

Charles Schwab, Hong Kong, Ltd., is a subsidiary of Charles Schwab Corporation and is registered with the Securities & Futures Commission (“SFC”) to carry out the regulated activities in dealing in securities and advising on securities under CE number ADV256. The company currently provides services via its Hong Kong office, its telephone system (+852 2101-0511) and web site (www.schwab.com.hk). 

(0225-TBLT)

Happy Chinese New Year 2025: Jiangsu’s Intangible Cultural Heritage Takes the Global Spotlight

NANJING, China, Feb. 13, 2025 /PRNewswire/ — On December 4th, 2024, UNESCO inscribed the “Spring Festival, Social Practices of the Chinese People in Celebration of Traditional New Year” on its Representative List of the Intangible Cultural Heritage of Humanity. To mark this exciting milestone, @Visit Jiangsu has launched a dazzling array of “Happy Chinese New Year 2025” festive events across Facebook, X, Instagram, YouTube, and TikTok as part of the Jiangsu Provincial Department of Culture and Tourism’s global outreach and promotion campaign.

Blending Jiangsu’s rich and diverse intangible cultural heritage with cutting-edge technology, the global cultural feast weaves a magical tapestry of Jiangsu’s Chinese New Year traditions, including the Qinhuai Lantern Fair, Taohuawu Woodblock New Year Paintings and Taibo Temple Fair, all taken to the next level with AR filters, online games, digital exhibitions and more.

Traditional Culture Meets Pioneering Technology: Intangible Cultural Heritage Revived

During the “Happy Chinese New Year 2025” celebrations, @Visit Jiangsu has been pushing the boundaries of international cultural communications through digital technology to share its beloved intangible cultural heritage with a global audience. One of the followers’ favorites is the AR filter inspired by the Taohuawu Woodblock New Year Paintings that launched on January 13th. With over 580,000 views and 47,000 interactions, people from all over the world used the filter to create their own version of Chinese New Year greeting cards, embracing the spirit of the festive season while exploring Jiangsu’s traditional culture and art from a whole new perspective.

Captivating Games Get Fans in the Spirit: Jiangsu’s New Year Traditions Go Global

On Chinese New Year’s Eve, a fun matchup game launched by @Visit Jiangsu connected global culture lovers across multiple social media platforms. Tens of thousands of people dived into the journey of Jiangsu festive cuisines, matching the enchanting pictures of dishes like Eight Treasure Gourd Duck and Plum Blossom Cake with their names. And many fans injected even more creativity into the game by crafting their own personalized Chinese New Year’s Eve menus. The fascinating blend of culture and fun gained over 164,000 views and 22,000 interactions, spreading the warm Chinese New Year culture of family reunions to every corner across the globe.

And on January 29th, the 1st day of the Year of the Snake, the festive vibes among the global audience are brought to the climax with a drawing challenge, where they are encouraged to draw a cartoon snake’s missing body in the most creative way. @Visit Jiangsu received creative drawings of all sorts of styles created with all kinds of drawing tools from their global followers. With over 223,000 views and 36,000 interactions, every piece of artwork became a powerful cultural ambassador of “Charm of Jiangsu“, deepening the global audience’s awareness and understanding of not only the culture of Jiangsu but also Chinese culture in general.

Up-close to the Jiangsu Splendor: Intangible Cultural Heritage and Authentic Chinese New Year Vibes

As one of the highlights during the Chinese New Year celebrations, the Qinhuai Lantern Fair in Nanjing, Jiangsu, has been attracting numerous visitors every year since over 1,700 years ago. This time, Miss Su, the digital cultural ambassador of Jiangsu, takes viewers worldwide on a virtual tour through the stunning lantern displays, and provides vibrant insights into the profound cultural background and techniques behind them. The unique charm of Qinhuai Lanterns reached over 30,000 global viewers, bringing a piece of Jiangsu’s legacy to their hearts.

Meanwhile, the Taibo Temple Fair in Wuxi, Jiangsu, renowned for its historical roots and rich cultural significance, also played a vital role in the 2025 Chinese New Year celebrations. Through an online digital exhibition, a thousand-year-old scroll of the fair’s history, traditions and folk art performances unfolded before an international audience, reaching approximately 41,000 views and 10,000 interactions. “I feel more bonded to Jiangsu culture than ever.” One of the channel’s overseas followers commented, giving us a glimpse into the strengthened cultural exchange between Jiangsu and the world.

As part of the “Happy Chinese New Year 2025” celebrations, @Visit Jiangsu also published 11 posts featuring Chinese New Year holiday travel plans across Jiangsu, as well as 2 posts spotlighting Miss Su’s must-visit recommendations, receiving around 1.37 million views and 178,000 interactions altogether. In addition, innovative short videos created by @Visit Jiangsu also received overwhelmingly positive feedback. Nantong Langshan Mountain Lantern Show captivated audiences with an immersive display of Jiangsu’s distinctive lantern fair culture, creating a vibrant festive atmosphere. With 1.2 million views and 46,000 likes, the fair won the hearts of numerous international viewers. Meanwhile, Origins of the Year of the Snake delved into the cultural significance of the Year of the Snake, receiving 1.1 million views and 110,000 likes by sparking interest and discussions in traditional Chinese culture among overseas audiences.

In this digital age, celebrating traditions together, no matter where we are and who we are, has never been more meaningful. By leveraging cutting-edge technology with a touch of innovation, @Visit Jiangsu is dedicated to bridging cultures between the East and the West in an innovative way, making the world a better place for generations to come.

Stay tuned with @Visit Jiangsu on Facebook, X, Instagram, YouTube, and TikTok to be a part of the global cultural exchange and dive into upcoming events around Jiangsu.

Study Results Abstracts From Kelun-Biotech’s TROP2 ADC Sacituzumab Tirumotecan (sac-TMT) At 2025 ASCO Genitourinary Cancers Symposium

CHENGDU, China, Feb. 13, 2025 /PRNewswire/ — At the American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium 2025, to be held in San Francisco, USA, from Feb. 13-15, 2025, Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd (”Kelun-Biotech” will present efficacy and safety results from the Phase 1/2 KL264-01/MK-2870-001 study (NCT04152499) of its anti-TROP2 ADC sacituzumab tirumotecan (sac-TMT, formerly SKB-264/MK-2870) as monotherapy in patients with unresectable, locally advanced or metastatic urothelial carcinoma (UC) who progressed on or after prior anti-cancer therapies. These findings will be presented in a poster session on February 14, 2025, local time (Abstract #796).

The abstract for the above study was also published on the official website of the ASCO GU Cancers Symposium 2025 on February 10, 2025, local time.

UC

Eligible participants had histologically/cytologically confirmed locally advanced or metastatic UC, had experienced progression of disease on ≥1 prior line of platinum-based therapy and had received prior anti-PD-(L)1 therapy; platinum-ineligible patients were eligible if they received prior anti-PD-(L)1 therapy (prior neoadjuvant/adjuvant therapy counted as a line of therapy if patients progressed within 12 months). Patients had Eastern Cooperative Oncology Group (ECOG) performance status (PS) ≤1 and measurable disease by CT/MRI. Patients received sac-TMT 5 mg/kg every two weeks (Q2W) until progression of disease, unacceptable toxicity or withdrawal of consent.

As of data cutoff on June 30, 2024, 49 treated patients had a minimum follow-up of ≥9 weeks. Eleven patients received sac-TMT as 2L treatment; 38 received sac-TMT as 3L+ treatment. Median age was 62 and 61 years old, respectively; most patients were Asian (82%; 100%). Median (range) follow-up was 9.5 (7.5-16.2) months and 11.7 (7.8-17.4) months, respectively. Among all patients, objective response rate (ORR) was 31%. Efficacy data are shown below:

Outcome

UC 2L

sac-TMT 5 mg/kg

(n=11)

UC 3L+

sac-TMT 5 mg/kg

(n=38)

Confirmed ORRa n (%)

5 (45)

10 (26)

   95% CI

16.7-76.6

13.4-43.1

CR n (%)

1 (9)

0

PR n (%)

4 (36)

10 (26)

SD n (%)

3 (27)

17 (45)

PD n (%)

2 (18)

10 (26)

Not evaluable n (%)

1 (9)

1 (3)

Median DoRb, months (range)

NE (3.5+ to 13.9+)

NE (2.1 to 15.0+)

Median PFSb, months (95% CI)

5.8 (1.7-NE)

5.0 (3.5-7.4)

Median OSb, months (95% CI)

NE (2.0-NE)

11.5 (8.9-NE)

CI=Confidence interval, CR=Complete response, PR=Partial response, SD=Stable disease, PD=Progression of disease, DoR=Duration of response, PFS=Progression-free survival, OS=Overall survival, NE=Not evaluable.

“+” No progressive disease or death as of last disease assessment.

a Includes all patients as-treated.

b Kaplan-Meier method for censored data.

By safety data cutoff (May 21, 2024), grade ≥3 treatment-related adverse events (TRAEs) occurred in 59% of patients. The most common Grade 3-4 TRAEs were anemia (39%), neutrophil count decreased (29%), white blood cells count decreased (16%), stomatitis (12%), and platelet count decreased (8%), which were generally reversible with dose modifications and/or supportive care. No Grade 5 TRAEs occurred; TRAEs led to sac-TMT discontinuation in one patient.

About sac-TMT

Sac-TMT, a core product of the Company, is a novel human TROP2 ADC in which the Company has proprietary intellectual property rights, targeting advanced solid tumors such as NSCLC, breast cancer (BC), gastric cancer (GC), gynecological tumors, among others. Sac-TMT is developed with a novel linker to conjugate the payload, a belotecan-derivative topoisomerase I inhibitor with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on the surface of tumor cells by recombinant anti-TROP2 humanized monoclonal antibodies, which is then endocytosed by tumor cells and releases KL610023 intracellularly. KL610023, as a topoisomerase I inhibitor, induces DNA damage to tumor cells, which in turn leads to cell-cycle arrest and apoptosis. In addition, it also releases KL610023 in the tumor microenvironment. Given that KL610023 is membrane permeable, it can enable a bystander effect, or in other words kill adjacent tumor cells.

Previously, the National Medical Products Administration (NMPA) has approved the marketing of sac-TMT in China for 2L+ advanced triple negative breast cancer (TNBC), and accepted two supplemental new drug applications (sNDA) seeking the approvals of sac-TMT monotherapy for 2L/3L EGFR-mutant non-small cell lung cancer (NSCLC).

In May 2022, the Company licensed the exclusive rights to MSD (the tradename of Merck & Co., Inc, Rahway, NJ, USA) to develop, use, manufacture and commercialize sac-TMT in all territories outside of Greater China (which includes Mainland China, Hong Kong, Macao and Taiwan).

About Kelun-Biotech

Kelun-Biotech(6990.HK)is a holding subsidiary of Kelun Pharmaceutical (002422.SZ), which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. The company focuses on major disease areas such as solid tumors, autoimmune, inflammatory, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. The Company is committed to becoming a leading global enterprise in the field of innovative drugs. At present, the Company has more than 30 ongoing key innovative drug projects, of which 3 projects have been approved for marketing, 1 project is in the NDA stage, and more than 10 projects are in the clinical stage. The company has established one of the world’s leading proprietary ADC platforms, OptiDC™, and has 1 ADC project approved for marketing, 1 ADC project in NDA stage, and multiple ADC or novel ADC projects in clinical or preclinical research stage. For more information, please visit https://kelun-biotech.com/.