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Sustainable Shared Transport and Fujitsu launch open platform for joint transportation and delivery in Japan, enhancing logistics efficiency across industries

TOKYO and KAWASAKI, Japan, Jan. 27, 2025 /PRNewswire/ — Sustainable Shared Transport Inc. (SST), a subsidiary of Yamato Holdings Co., Ltd. and Fujitsu Limited, today announced the launch of a joint transportation and delivery system for shippers and logistics providers in Japan. SST will start providing the service on February 1, 2025.

SST, established on May 21, 2024, aims to build a sustainable supply chain through this platform, which utilizes standardized pallet transportation (physical) and standardized information exchange (digital). This new joint transportation and delivery service, provided by SST, matches shippers and logistics providers on the system, primarily focusing on trunk transport.

Fujitsu, recognizing the crucial role of responsible supply chain management in its commitment to developing a digital society, views solving logistics challenges as a key priority within its Materiality. Fujitsu will utilize SST’s joint transportation and delivery service as a shipper and has jointly built a data integration platform with the company. On February 1, 2025, Fujitsu will invest 50 million yen in SST.

This initiative comes as the logistics industry in Japan faces various challenges, including transportation capacity shortages and climate change concerns, and all companies are being urged to undergo significant transformations to further improve logistical efficiency and create an attractive work environment. Furthermore, to foster sustainable logistics growth, the Japanese government amended legislation, encouraging shippers and logistics companies to implement logistics optimization measures from April 2025 onwards.

However, industry-specific systems, standards, and business practices hinder widespread solutions. To address this task, the Yamato Group established SST in May 2024, fostering open collaboration across industries. Together with Fujitsu, SST has developed a foundational system for data integration across companies.

Future Plans

SST and Fujitsu aim to create a sustainable and cross-industry supply chain by combining Yamato Group’s partnerships with approximately 1.7 million corporate clients and over 3,500 logistics providers, its transportation network and operational expertise, and Fujitsu’s expertise in manufacturing, distribution, and system development. Furthermore, the two companies will build a digital infrastructure linking commercial and logistics information, and promote data integration with related organizations and platforms to optimize and strengthen the entire supply chain.

For full release click here:

Tiger Brokers Wins Two Prestigious Awards from CME Group, Strengthening Its Global Fintech Leadership

HONG KONG, Jan. 27, 2025 /PRNewswire/ — Tiger Brokers (HK) Global Limited (“Tiger Brokers (HK)”) has been honored with two prestigious awards by the Chicago Mercantile Exchange Group (CME Group): “Broker Program Key Partner 2024” and “Futures and Options Nurturer 2024.” These accolades not only reinforce Tiger Brokers’ position as a leading global fintech broker but also recognize its outstanding achievements in the futures and options investment sector.


As a world-class online securities trading platform, Tiger Brokers is dedicated to providing clients with a superior trading experience and a diverse range of investment options. Last year, Tiger Brokers became one of the first mainstream online brokerage firms in Hong Kong to support the trading of both traditional securities and virtual assets on a single platform. Currently, professional investors in Hong Kong can access Tiger Brokers’ flagship platform, Tiger Trade, to conduct one-stop trading of 20 different virtual assets, including Bitcoin (BTC) and Ethereum (ETH), as well as stocks, options, futures, US Treasuries, funds, and other global assets. This integration allows customers to manage global asset allocation more conveniently and seamlessly without the need to open multiple accounts across different brokers and platforms.

Felix Huang, Deputy CEO of Tiger Brokers, said “The awards from the CME Group recognize outstanding Asian brokers in the marketing and promotion of CME Group products. This recognition is a testament to Tiger Brokers’ unwavering commitment to serving global investors and injects new momentum into the Company’s future business development. Tiger Brokers will continue to invest in technology, products, and services, constantly optimizing and expanding its trading product range to provide clients with a more premium, convenient, and comprehensive global financial investment experience. Additionally, we will further deepen our strategic cooperation with international exchanges to jointly drive fintech innovation and development in the Hong Kong and global financial markets.”

About Tiger Brokers (HK)

Tiger Brokers (HK) Global Limited (Central number: BMU940) holds type 1, 2, 4, 5 and 9 licenses of the Securities and Futures Commission. Starting from 30th November 2022, with Tiger Trade, Tiger Brokers’ flagship app, Hong Kong users can trade financial products from major markets around the world, such as Hong Kong stocks, warrants, options, US stocks, US fractional shares and ETFs, etc., providing a one-stop solution to their investment needs. In the future, we will continue to expand our trading markets and categories to better serve Hong Kong investors.

About Tiger Brokers

Tiger Brokers (Nasdaq: TIGR), founded in 2014, is a leading online brokerage group with a focus on redefining global investing with technologies for the next generation.

Since our inception, the company has relentlessly offered a superior user experience to let everyone enjoy efficient and smart global investing, by bringing a multitude of quality financial products and services across brokerage, employee stock ownership plan (ESOP) management, investment banking, wealth management, investor community, and investor education in our pursuit of becoming a world-leading online brokerage group.

We strive to elevate financial technology R&D to a new level. While we inherit the best traditions from the financial sector and blend them with the best minds of tech experts, we develop our own technology infrastructure—an aggregation that enables multi-currency trading of various products across markets, guaranteeing our reliable, secure, and scalable services accessible to all with low latency.

Currently, we serve over 10 million users and over 2 million account holders worldwide on our flagship platform “Tiger Trade”, own 77 licenses and qualifications in different markets, and have over 1,000 employees on the team in Hong Kong, Singapore, New Zealand, the US, Australia, and Mainland China. In 2019, the company was listed on Nasdaq as UP Fintech Holding Limited under the ticker TIGR.         

Innophys Launches Sales of “Muscle Suit (R)” Powered Exoskeletons in Singapore

– Addressing Needs of Aging Population and Reducing Workload, Aiming for Expansion in Southeast Asian Markets –

TOKYO, Jan. 27, 2025 /PRNewswire/ — Innophys Co., Ltd. (hereinafter referred to as “Innophys”), a venture originating from Tokyo University of Science, located in Hachioji City, Tokyo, started sales in Singapore of its Muscle Suit (R) powered exoskeleton series on January 6.

Image1:
https://cdn.kyodonewsprwire.jp/prwfile/release/M106291/202501223205/_prw_PI1fl_V3mwXd0T.jpg

Innophys launched the lightweight model “Muscle Suit Soft-Power EASY-LIFT” in October last year. The company is progressing with its market expansion, tailoring its offerings to meet local needs.

Following its foray into Romania last year, Innophys has begun selling its Muscle Suit (R) in Singapore as part of its efforts to strengthen its presence in overseas markets. Singapore boasts a high economic standard and is proactive in enhancing labor conditions, adopting advanced technologies. Additionally, as an important logistics hub, Singapore has seen rising interest in the Muscle Suit (R) series for tasks such as cargo handling in factories and warehouses, as well as in the healthcare and caregiving sectors.

The country faces a growing need to address the aging population and reduce labor burdens. Through the Muscle Suit (R) model, Innophys aims to improve worker safety and productivity. Singapore is positioned as a hub for the Southeast Asian market. By leveraging the country as a base, Innophys is committed to further expanding into additional overseas markets.

The current overseas Muscle Suit (R) distributors are located in the following countries/regions (as January 27, 2025):

Asia: Mainland China, South Korea, Taiwan region, Hong Kong SAR & Macau SAR, Malaysia, Thailand, Singapore

– EU: France, Spain, Italy, Germany, Poland, Denmark, Estonia, Latvia, Lithuania, Romania, Czech Republic, Slovakia, Slovenia

Latin America: Mexico

Official global websites of Muscle Suit (R):
Muscle Suit: https://innophys.net/musclesuit/
Information on oversea distributors: https://innophys.net/musclesuit/distributors-and-retailers/

About Muscle Suit Soft-Power EASY-LIFT

Image2:
https://cdn.kyodonewsprwire.jp/prwfile/release/M106291/202501223205/_prw_PI2fl_72dluVqM.jpg

Released on October 21, 2024, this entry-level model is designed for tasks like farming, construction, and transport, reducing lower back strain by 33%. Weighing only 310g, it is lightweight, flexible, easy to wear, washable, and affordable, making it highly practical for users.

129Knots launches with $10M investment led by Sing Fuels, over $500M deal pipeline, and first of its kind real-world asset origination to distribution (OTD) technology

SINGAPORE, Jan. 27, 2025 /PRNewswire/ — Global fintech venture 129Knots has launched with a $10 million investment led by  Sing Fuels. Backed by a $500 million deal pipeline, it is set to revolutionize the industry  with its real-world asset origination to distribution (OTD) technology.

(L-R) Mahesh Kumar, Vikash Dhanuka
(L-R) Mahesh Kumar, Vikash Dhanuka

The OTD technology will reinvent deep-tier industries by delivering and deploying scalable liquidity solutions through secure chain technologies. This will elevate supply  chains into high-value assets that meet investment-grade standards. Moreover, the  platform is driven by a proprietary data driven credit engine named Tribal Knots. Tribal  Knots uses advanced machine learning and integrates both structured and  unstructured data from global networks to offer real-time insights into buyer behavior,  transaction patterns, and industry benchmarks.

129Knots was incubated and launched under the Singapore Economic Development  Board (EDB) Corporate Venture Launchpad programme, which supports companies  with venture creation and startup partnerships from Singapore. The corporation  partnered with McKinsey & Company to validate its market opportunity, which led to the  creation of 129Knots to drive innovation in the real-world asset economy. The  additional support from Enterprise Singapore and IBM consulting, combined with the  $10 million capital injection, will help scale 129Knots globally as it aims to solve the  $2.5 trillion gap between trade finance requests and approvals, which is its first market  entry value proposition.

129Knots will also offer a vast range of next-gen OTD solutions across trade credit,  asset tokenization, programmable money, stablecoin-powered transactions, blockchain  technology, advanced trade audit trails, innovative credit risk assessment models, and  trade governance. These technologies will redefine real-world asset management,  increase transparency, and enhance risk mitigation beginning in the marine energy  transition sector, with plans to expand into other high growth industries.

The pipeline of over $500 million in deals, combined with the financial vote of  confidence from one of Singapore’s fastest-growing companies, is clear evidence of the  overwhelming demand for state-of-the-art asset origination to distribution platform,  according to 129Knots.

Vikash Dhanuka, Founder & Group CEO, said: “The homogeneous approach of  balance-sheet led lending is obsolete. A one-size-fits-all approach simply fails in a  dynamic sector such as global trade. At 129Knots, we redefine the game with a tailored  integration of OTD technology, business risk management, and finance.

As an example, a small marine energy supplier in an emerging market can tokenize  receivables using programmable money, enabling instant credit disbursement upon  achieving predefined milestones verified in real-time through advanced governance  audit trails. This innovation provides financiers with full visibility into trade assets, mitigates risks and unlocks capital previously unavailable through conventional  channels.”

Mahesh Kumar, co-founder and interim CEO at 129Knots, said: “At the forefront of the  real-world asset economy, 129Knots strives to become the world’s most trusted  originator and distributor of real-world assets and to revolutionize deep-tier trade industries with safe, efficient, and next-gen secure chain technologies.

129Knots is therefore more than just a fintech platform; it is designed for scalability and  adaptability. Our cutting-edge OTD technology seamlessly provides end-to-end data  visibility from asset origination to distribution. 

About 129Knots:

129Knots is pioneering a state-of-the-art, real-world asset origination to distribution  (OTD) platform. Our breakthrough technology will reinvent deep-tier industries by  delivering and deploying scalable liquidity solutions through secure chain technologies.  Powered by a proprietary credit engine named Tribal Knots, 129Knots will elevate  supply chains into high-value assets that meet investment-grade standards. 

129Knots was incubated and launched under the Singapore Economic Development  Board (EDB) Corporate Venture Launchpad programme, with additional support from  McKinsey & Company, Enterprise Singapore and IBM consulting.

Visit 129Knots here for more info.

 

SERES Leads Chinese EV Innovation at Davos, Championing Global Collaboration for the Intelligent Age

CHONGQING, China, Jan. 27, 2025 /PRNewswire/ — During the World Economic Forum’s 2025 annual meeting held from January 20-24 in Davos-Klosters, Switzerland, nearly 3,000 representatives from 130 countries and regions discussed the theme “Collaboration for the Intelligent Age,” exploring topics such as reimagining growth and industries in the intelligent era. SERES Vice President Kang Bo was the sole Chinese new energy vehicle enterprise representative invited to attend and participate in multiple forum activities.

Media reports
Media reports

In today’s globalized landscape, open collaboration has become essential. By sharing resources and expertise across industries, innovative business models and development approaches are emerging, enabling high-quality collaboration in the intelligent age. Kang Bo emphasized that sector boundaries are becoming increasingly fluid, with cross-industry collaboration becoming critical. SERES has substantially benefited from this collaborative approach, building partnerships with global automotive suppliers and leading technology companies to enhance its products’ intelligence and connectivity. The company now shares its powertrain technology with 12 partners worldwide, driving collective progress in the automotive industry.

Media reports
Media reports

“Advancements in new quality productive forces have propelled China’s new energy vehicle industry to new heights,” Kang Bo highlighted. Domestic automakers have made significant strides in core competencies, developing cutting-edge technologies in electric powertrains, artificial intelligence, new materials, and advanced manufacturing processes. These innovations have strengthened the entire industry value chain, positioning Chinese vehicle enterprises competitively in the high-end market. SERES stands as a prime example of high-quality innovation, with its brand image and perceived value continuously evolving.

In 2024, SERES achieved remarkable results, with annual new energy vehicle sales exceeding 420,000 units, representing a year-on-year growth of over 182%. Kang Bo believes the core competitiveness of intelligent vehicles lies in Software-Defined Vehicles (SDV). Through continuous over-the-air (OTA) updates, they provide users with an innovative and frequently renewed driving experience, enhancing both software features and overall hardware performance throughout the vehicle’s lifecycle.

SERES has pioneered innovative technology in intelligent manufacturing, establishing a globally benchmarked Super Factory in Chongqing. The facility, housing over 3,000 robots, achieves 100% automation in critical processes and comprehensive vehicle inspections, significantly boosting production efficiency and product quality. The company has implemented 10,000-ton integrated die-casting technology, dramatically reducing component count and enhancing overall vehicle quality.

 

FOUR POINTS BY SHERATON BANGKOK, SUKHUMVIT 22 OPENS ITS DOORS IN THE HEART OF THE THAI CAPITAL

 New Hotel to Elevate Business and Leisure Stays with Striking Vintage Design and Modern Amenities, Surrounded by World-Class Attractions in the Commercial Center of Bangkok

BANGKOK, Jan. 27, 2025 /PRNewswire/ — Four Points by Sheraton, part of Marriott Bonvoy’s portfolio of over 30 extraordinary hotel brands, proudly announces the opening of Four Points by Sheraton Bangkok, Sukhumvit 22. Redefining urban hospitality, this stylish new hotel combines timeless design concept with seamless connectivity and modern amenities to provide guests with a comfortable, convenient and inspiring stay in the beating heart of Thailand’s capital city.

FOUR POINTS BY SHERATON BANGKOK, SUKHUMVIT 22 OPENS ITS DOORS IN THE HEART OF THE THAI CAPITAL
FOUR POINTS BY SHERATON BANGKOK, SUKHUMVIT 22 OPENS ITS DOORS IN THE HEART OF THE THAI CAPITAL

“We are excited to welcome a new Four Points by Sheraton property to Bangkok’s buzzing Sukhumvit district,” said Brad Edman, Market Vice President – Thailand, Cambodia & Myanmar, Marriot International. “This hotel will resonate with guests who want to kick back, relax and explore Bangkok’s many attractions. With its unique design, genuine hospitality and great value, Four Points by Sheraton Bangkok, Sukhumvit 22 will meet the rising demand from business and leisure travelers in this dynamic metropolis.”

Four Points by Sheraton Bangkok, Sukhumvit 22 is strategically located in Bangkok’s bustling Sukhumvit district, just 300 meters from The EmDistrict – a major retail and lifestyle haven comprising three world-class malls, The Emporium, EmQuartier and EmSphere, plus UOB Live, Southeast Asia’s newest live entertainment venue – and surrounded by corporate offices, cultural attractions, and the city’s vibrant nightlife. Queen Sirikit National Convention Centre (QSNCC) is less than 3km away, and the BTS SkyTrain stations at Phrom Phong and Asoke, and MRT Sukhumvit put the entire city within easy reach.

The hotel’s striking interior concept was created by Pomme Chan, the iconic Thai designer, and blends modern urban and industrial design with vintage elements, including old shophouse gates, chandeliers and street photography. With original artworks and installations by Bangkok Street artists, this hotel captures the transformation of the Sukhumvit area from the mid-20th Century to the present day.

The 333 rooms & suites are restful retreats where travelers can take a break from the city’s fast-paced energy. With soothing tones and textures, comfortable king or twin beds, dedicated workspaces with integrated USB ports, Bluetooth alarm clocks with wireless charging, fast Wi-Fi, 55″ LED TVs, and refreshing bathrooms with rain showers, every guest can unwind and stay productive.

Every day can start with breakfast at The Mesh, the casual all-day dining destination which also sets the scene for daytime bites and business lunches. Then as evening falls, this inviting venue transforms into a contemporary beer house and sports bar, where hotel guests and local residents can come together and sip Bangkok’s BestBrews™, in line with Four Points’ signature craft beer program, along with a wide range of freshly prepared Thai and international dishes.

The Mesh Lounge is a flexible and fully connected space for corporate meetings and social events with up to 25 guests, while the boardrooms can host inspiring sessions with up to 10 people, all equipped with state-of-the-art technology. When visitors are not working or exploring the city, they can work out at the 24/7 fitness center or chill out at the rooftop pool, with stunning views of Bangkok’s skyline.

“At Four Points by Sheraton Bangkok, Sukhumvit 22, we aim to redefine urban hospitality with timeless design, convenient amenities and thoughtful service,” said Peter Feran, General Manager, Four Points by Sheraton Bangkok, Sukhumvit 22. “We are delighted to welcome guests to this dynamic part of Bangkok and provide them with everything they need to rest, relax and stay connected, all underpinned by the timeless standards of the Four Points by Sheraton brand.”

The hotel participates in Marriott Bonvoy – the award-winning travel program from Marriott International – allowing members to earn and redeem points for their stay at the new hotel, and at other hotels and resorts across Marriott Bonvoy’s portfolio of extraordinary hotel brands. With the Marriott Bonvoy app, members enjoy a level of personalization that allows them to travel with peace of mind.

For more information or to book your stay, please visit www.fourpointsbangkoksukhumvit22.com.

About Four Points by Sheraton

Four Points by Sheraton is a global brand with over 310 hotels in over 45 countries and territories. At Four Points, travel is reinvented where timeless classics are woven with modern details, paired with genuine service in a casual environment—all around the world. Four Points hotels can be found in the heart of urban centers, near the beach, by the airport, or in the suburbs. Each hotel offers a familiar place to kick back and relax with an authentic sense of the local, where guests can watch sports and enjoy the brand’s Best Brews® program. Four Points is proud to participate in Marriott Bonvoy®, the global travel program from Marriott International. The program offers members an extraordinary portfolio of global brands, exclusive experiences on Marriott Bonvoy Moments and unparalleled benefits including free nights and Elite status recognition. To enroll for free or for more information about the program, visit marriottbonvoy.com. To learn more about Four Points, visit us online.

About Marriott Bonvoy®

Marriott Bonvoy, Marriott International’s portfolio of more than 30 hotel brands and 10,000 global destinations, offers renowned hospitality in the most memorable locations around the world. The award-winning travel program and marketplace gives members access to transformative, eye-opening experiences around the corner and across the globe. To enroll for free or for more information about Marriott Bonvoy, visit marriottbonvoy.com. To download the Marriott app, go here. Travelers can also connect with Marriott Bonvoy on Facebook, X, Instagram, and TikTok.

Shanghai Lights Up in Celebration of UNESCO Recognition of China’s Spring Festival as an Intangible Cultural Heritage

Shanghai Invites the World to Celebrate Its Rich Heritage during the Spring Festival Celebrations

SHANGHAI, Jan. 27, 2025 /PRNewswire/ — On December 4, 2024, the United Nations Educational, Scientific and Cultural Organization (UNESCO) added China’s Spring Festival to its Representative List of the Intangible Cultural Heritage of Humanity. The recognition celebrates the Spring Festival’s significant role in fostering social practices and communal spirit as the Chinese people welcome their traditional new year. The designation will further boost Shanghai as a must-visit destination during this year’s Spring Festival celebrations.


Shanghai is hosting a series of exciting events that highlight this rich cultural heritage. The city’s renowned Shanghai Lantern Festival, a tradition with a history that spans more than two millennia, will illuminate the festivities. This year, the festival draws inspiration from the ancient “Classic of Mountains and Seas,” featuring the theme “The Beauty of All Things, the Wonder of Existence.” Visitors to the Yuyuan Lantern Festival can expect an enchanting experience with displays that transform the area into a mythical jungle paradise adorned with fluttering butterflies, vibrant flowers, lush forests, and winding snakes.


Moreover, historic locales within Shanghai, including Nanxiang, Luodian in Baoshan, Fengjing in Jinshan, and Qingxi Old Street, will each present their unique interpretations of lantern art. The displays not only dazzle the senses but also pay homage to the enduring folk traditions that enrich China’s cultural tapestry. Throughout the Spring Festival period, over 200 performances, exhibitions, and interactive experiences will be showcased, providing a deep dive into the festive and communal atmosphere that characterizes this time of year.

The city of Shanghai extends a warm invitation to visitors from around the world to explore the cultural magnificence of the Spring Festival and the mesmerizing beauty of the Shanghai Lantern Festival. The celebration is a testament to the living heritage that UNESCO aims to protect and promote for future generations.

CStone Partners with SteinCares to Market Sugemalimab in Latin America

  • CStone will receive upfront, regulatory and commercial milestone payments, and book revenue from SteinCares through the supply of sugemalimab in 10 Latin American (LATAM) countries.
  • This marks CStone’s third major global commercialization partnership for sugemalimab, with additional deals in Western Europe, Southeast Asia, Canada, and other regions anticipated soon. CStone has received marketing approval for sugemalimab in the EU, EEA countries (Iceland, Liechtenstein, and Norway), and the UK, while actively advancing regulatory submissions for additional indications.

SUZHOU, China, Jan. 27, 2025 /PRNewswire/ — CStone Pharmaceuticals (“CStone”, HKEX: 2616), an innovation-driven biopharmaceutical company focused on the research and development of anti-cancer therapies, today announced a strategic commercialization partnership with SteinCares, a leading pharmaceutical company with over 40 years of experience and a strong presence in Latin America. Under this agreement, SteinCares will gain the commercialization rights for sugemalimab in 10 LATAM countries, including Brazil, Argentina, Mexico, Chile, Colombia, Costa Rica, Panama, Peru, Guatemala and Ecuador.

As part of this collaboration, SteinCares will be responsible for the regulatory affairs and commercialization activities of sugemalimab in these regions. CStone will supply sugemalimab and will receive upfront, regulatory, and commercial milestone payments as well as revenue from product supply.

Dr. Jason Yang, CEO, President of R&D and Executive Director at CStone, stated, “Following our successful market entries in Central and Eastern Europe, Switzerland, as well as the Middle East and Africa, we are excited to announce another key milestone in the global expansion of sugemalimab. As the first anti-PD-L1 monoclonal antibody approved in both the EU and UK for first-line, all-comer, Stage IV non-small cell lung cancer (NSCLC), sugemalimab is well-positioned for success in Latin America. SteinCares’ extensive distribution network and deep marketing expertise will significantly enhance sugemalimab’s reach.

We are also actively discussing with international partners in Western Europe, Southeast Asia, and Canada, while advancing regulatory submissions for additional indications of sugemalimab. We are confident that these efforts will further unlock the therapeutic and commercial potential of sugemalimab, ultimately benefiting patients worldwide.”

Mitchell Waserstein, CEO of SteinCares, added: “This agreement with CStone represents a significant step forward in our mission to create healthcare opportunities for patients in LATAM. At SteinCares, we are committed to providing more Latin Americans with greater access to safe, innovative, and affordable therapies. With our extensive experience and established sales network across the region, we are confident in our ability to successfully commercialize sugemalimab in LATAM and make a meaningful impact on patients’ health and well-being.”

About Sugemalimab

The anti-PD-L1 monoclonal antibody sugemalimab was developed by CStone using OmniRat® transgenic animal platform, which allows creation of fully human antibodies in one step. Sugemalimab is a fully human, full-length anti-PD-L1 immunoglobulin G4 (IgG4) monoclonal antibody, which may reduce the risk of immunogenicity and toxicity for patients, a unique advantage over similar drugs. Sugemalimab’s differentiated molecular design enables a dual mechanism of action that not only blocks PD-1/PD-L1 interaction, but also induces antibody dependent cellular phagocytosis (ADCP) by cross-linking PD-L1 expressing tumor cells with tumor associated macrophages (TAMs) without harming Effector T-cells. This differentiation has resulted in competitive efficacy/safety across a variety of tumor types.

The National Medical Products Administration (NMPA) of China has approved sugemalimab for five indications:

  • In combination with chemotherapy as first-line treatment of patients with metastatic squamous and non-squamous NSCLC;
  • For the treatment of patients with unresectable Stage III NSCLC whose disease has not progressed following concurrent or sequential platinum-based chemoradiotherapy;
  • For the treatment of patients with relapsed or refractory extranodal NK/T-cell lymphoma;
  • In combination with fluorouracil and platinum-based chemotherapy as first-line treatment of patients with unresectable locally advanced, recurrent or metastatic ESCC; and
  • In combination with fluoropyrimidine- and platinum-containing chemotherapy as first-line treatment for unresectable locally advanced or metastatic gastric or gastroesophageal junction (G/GEJ) adenocarcinoma with a PD-L1 expression (Combined Positive Score [CPS] ≥5).

The European Commission (EC) has approved sugemalimab (brand name: Cejemly®) in combination with platinum-based chemotherapy for the first-line treatment of patients with metastatic NSCLC with no sensitizing EGFR mutations, or ALK, ROS1 or RET genomic tumor aberrations.

The Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom has approved the marketing authorization application for sugemalimab in combination with platinum-based chemotherapy for first-line treatment of metastatic NSCLC with no sensitizing EGFR mutations, or ALK, ROS1 or RET genomic tumor aberrations.

About CStone 

CStone (HKEX: 2616), established in late 2015, is an innovation-driven biopharmaceutical company focused on the research and development of anti-cancer therapies. Dedicated to addressing patients’ unmet medical needs in China and globally, the Company has made significant strides since its inception. To date, the Company has successfully launched 4 innovative drugs and secured approvals for 16 new drug applications (NDAs) covering 9 indications. The company’s pipeline is balanced by 17 promising candidates, featuring potentially first-in-class or best-in-class antibody-drug conjugates (ADCs), multispecific antibodies, immunotherapies and precision medicines. CStone also prides itself on a management team with comprehensive experiences and capabilities that span the entire drug development spectrum, from preclinical and translational research to clinical development, drug manufacturing, business development, and commercialization. For more information about CStone, please visit www.cstonepharma.com.

IR contact: ir@cstonepharma.com
PR contact: pr@cstonepharma.com

About SteinCares

SteinCares is a leader in commercializing and distributing specialty healthcare products in Latin America, including innovative pharmaceuticals, biosimilars, plasma-derived therapies and complex generics. With more than 40 years of progressive healthcare experience and operations in over 30 countries in Latin America and the Caribbean, SteinCares serves as a bridge between global pharmaceutical companies and the region’s healthcare providers. The company is deeply committed to creating healthcare opportunities that positively impact the lives of patients and their families in Latin America, with a vision of increasing access to innovative and cost-effective healthcare for patients in the region.

For more information, visit http://www.steincares.com/ or follow the company on LinkedIn.

Forward-looking statements 

The forward-looking statements made in this article only relate to events or information as of the date when the statements are made in this article. Except as required by law, we undertake no obligation to update or publicly revise any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect. All statements in this article are made on the date of publication of this article and may change due to future developments.

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