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Massimo Group Highlights Dealer Network Momentum, Organizational Expansion and Product-Led Strategy Entering 2026

GARLAND, Texas, Dec. 23, 2025 /PRNewswire/ — Massimo Group (NASDAQ: MAMO), a manufacturer and distributor of powersports vehicles and electric mobility solutions, today provided an update on its dealer network momentum, organizational expansion, and strategic initiatives as the Company prepares for accelerated dealer-led growth in 2026.

Massimo Group Dealer Momentum - New Sentinel and MVR Series
Massimo Group Dealer Momentum – New Sentinel and MVR Series

Dealer Network Momentum: 2025 Review and Expansion Outlook

Throughout 2025, Massimo made dealer network development a core pillar of its growth strategy, investing in channel expansion, internal infrastructure and dealer support capabilities. As the Company closes out the year, it continues to strengthen its authorized dealer footprint across key U.S. markets, expanding customer access while laying the groundwork for the rollout of higher-value product platforms.

Management views continued dealer network expansion as critical to supporting product commercialization, improving brand visibility and driving long-term, sustainable growth.

Q4 2025 Momentum and Dealer Signings

Massimo experienced increased momentum in dealer development during the fourth quarter of 2025. In Q4 alone, the Company executed agreements with several new dealer partners, reflecting growing interest from dealers aligned with Massimo’s evolving product strategy and partnership-driven model.

The Company believes this acceleration reflects improved execution, clearer product positioning, and increasing alignment between dealer market needs and Massimo’s long-term roadmap.

Organizational Expansion Supporting 2026 Growth

To support the next phase of dealer expansion, Massimo completed key organizational enhancements in 2025. The Company appointed a Vice President of Dealer Development to lead dealer recruitment, onboarding, and performance initiatives, reinforcing its commitment to building a scalable and high-quality dealer network.

In addition, Massimo hired a Manager of Fleet Sales, further strengthening its commercial capabilities and supporting the development of a more comprehensive dealer and fleet-oriented go-to-market strategy. These hires are integral to the Company’s refreshed dealer program, which is scheduled to launch in January 2026.

Management views these organizational additions as a transition from foundational network building toward a more execution-focused growth phase.

Product Strategy Supporting Dealer Profitability

Massimo’s dealer initiatives are supported by a differentiated product roadmap designed to improve dealer competitiveness and profitability, including:

  • The Sentinel Series, the Company’s next-generation UTV platform positioned to deliver higher-value features and performance.
  • The MVR HVAC Series, a new line of fully enclosed electric vehicles equipped with integrated heating and air conditioning, designed to help dealers differentiate their offerings in both consumer and commercial markets.

Several established dealer partners have already executed purchase agreements for units within these new product series. In addition, Massimo has initiated a preorder program for its 2026 Sentinel models, which is gaining solid early traction as dealers plan for the upcoming selling season.

Positioned for Dealer-Led Growth in 2026

Looking ahead to 2026, Massimo plans to increase its focus and investment in dealer development, emphasizing dealer quality, operational consistency, and long-term partnership alignment. Management believes the dealer channel will remain a key driver of sustainable revenue growth and successful product commercialization.

With an expanded dealer organization, growing dealer engagement, and an increasingly differentiated product lineup, Massimo believes it is well positioned to pursue disciplined, dealer-led growth while continuing to build long-term value for shareholders.

About Massimo Group (NASDAQ: MAMO)

Massimo Group is a manufacturer and distributor of powersports and electric vehicles headquartered in Garland, Texas. The company’s portfolio includes UTVs, ATVs, e-bikes, and electric utility vehicles known for performance, reliability and value.

Forward-Looking Statements

This press release contains certain forward-looking statements within the meaning of the federal securities laws with respect to Massimo Group. All statements other than statements of historical facts contained in this press release, including statements regarding Massimo Group’s future results of operations and financial position, Massimo Group’s business strategy, prospective costs, timing and likelihood of success, plans and objectives of management for future operations, future results of current and anticipated operations of Massimo Group are forward-looking statements. In some cases, forward-looking statements can be identified because they contain words such as “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “predict,” “project,” “target,” “potential,” “seek,” “will,” “would,” “could,” “should,” “continue,” “contemplate,” “plan,” and other words and terms of similar meaning. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including, but not limited to, risks relating to Massimo Group which may be affected by, among other things, competition, the ability of the combined company to grow and manage growth economically and hire and retain key employees; costs; changes in applicable laws or regulations; the possibility that Massimo Group may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties, including those listed under “Risk Factors” in our Annual Report on Form 10-K and other filings with the Securities and Exchange Commission. Moreover, Massimo Group operates in very competitive and rapidly changing environments. Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond Massimo Group’s control, you should not rely on these forward-looking statements as predictions of future events. Forward-looking statements speak only as of the date they are made. No assurance can be given regarding the forward-looking statements, and actual results may differ materially from those as indicated. Massimo Group undertakes no obligation to update these statements for revisions or changes after the date of this release, except as required by law.

Company Contact

Quenton Petersen
Vice President
Massimo Group
Email: ir@massimomotor.com 

Bybit Unveils Mantle Vault: Yield-Bearing, Flexible, and Built for Scalable Stablecoin Returns

DUBAI, UAE, Dec. 23, 2025 /PRNewswire/ — Bybit, the world’s second-largest cryptocurrency exchange by trading volume, in partnership with Mantle and Cian, announces the launch of Mantle Vault on Bybit On-Chain Earn today, a stablecoin on-chain yield asset management product offering competitive APR,  lower risk and highly flexible access through market-neutral strategies. Mantle Vault will become part of Bybit’s On-Chain Earn suite.

Mantle Vault is designed to optimize APR performance across market cycles powered by on-chain yield opportunities, targeting consistent performance even in volatility. Built for long-term stability, it combines institutional-grade DeFi infrastructure, flexible liquidity, and ease of access.

Bybit complements this integration by acting as the global access and distribution layer, allowing millions of users to enter Mantle’s onchain economy through a familiar interface while benefiting from fully onchain execution. The addition of Mantle’s latest flagship on-chain yield product aligns with Bybit Earn‘s vision to provide a pioneering product suite that helps users capture market opportunities in the fast-moving world of digital assets.

Mantle Network provides the scalable infrastructure required for these automated strategies, supporting fast settlement, low fees, and seamless integration across the broader ecosystem. CIAN specializes in developing and operating structured onchain yield products, abstracting complex DeFi strategies into simple, user-friendly vaults. By deploying natively on Mantle, CIAN enables stablecoin yield strategies to operate with greater efficiency, transparency, and composability within Mantle’s low-cost, high-performance execution environment.

“Mantle Vault represents a new era of accessible DeFi yield. This product delivers competitive, market-neutral returns with the flexibility users demand regardless of market conditions. It’s institutional-grade infrastructure made simple for everyone,” said Jerry Li, Head of Financial Products and Wealth Management at Bybit.

“This partnership demonstrates how Mantle serves as the execution and distribution layer for scalable onchain yield,” said Emily, Key Advisor at Mantle. “By abstracting complexity and delivering institutional-grade strategies through familiar access points, Mantle Vault brings structured DeFi yield closer to mainstream adoption.”

How It Works

Mantle Vault deploys user assets into audited, scalable DeFi protocols such as Aave V3, operating across both Ethereum Mainnet and the Mantle network. Yield is generated through stablecoin lending interest, staking rewards, and protocol incentives, which are all automatically compounded and managed through Cians on-chain execution infrastructure.

Key Features

  • Stable Yield Across Market Cycles: Targeting up to 5–10% APR in bear markets; up to 10-25% in bull markets
  • Market-Neutral Risk Management: Structured strategies built to mitigate drastic price volatility
  • Flexible Liquidity: Deposit or request withdrawal anytime
  • Low Entry Threshold: Starting from as little as 10 USDT or USDC

Mantle Vault sets a new standard for stablecoin asset management on Bybit On-Chain Earn, offering professionally structured DeFi yield that is simple, flexible, and built for scalability all in one platform.

Bybit Unveils Mantle Vault: Yield-Bearing, Flexible, and Built for Scalable Stablecoin Returns
Bybit Unveils Mantle Vault: Yield-Bearing, Flexible, and Built for Scalable Stablecoin Returns

Terms and conditions apply. For details on qualification rules, restrictions, and eligibility, users may visit: [Bybit x Mantle x Cian] Introducing Mantle Vault: Stablecoin on-chain yield strategy built for stability, flexibility, and scale

#Bybit / #CryptoArk / #IMakeIt

About Bybit

Bybit is the world’s second-largest cryptocurrency exchange by trading volume, serving a global community of over 80 million users. Founded in 2018, Bybit is redefining openness in the decentralized world by creating a simpler, open and equal ecosystem for everyone. With a strong focus on Web3, Bybit partners strategically with leading blockchain protocols to provide robust infrastructure and drive on-chain innovation. Renowned for its secure custody, diverse marketplaces, intuitive user experience, and advanced blockchain tools, Bybit bridges the gap between TradFi and DeFi, empowering builders, creators, and enthusiasts to unlock the full potential of Web3. Discover the future of decentralized finance at Bybit.com.

For more details about Bybit, please visit Bybit Press
For media inquiries, please contact: media@bybit.com
For updates, please follow: Bybit’s Communities and Social Media

Elong Power Holding Limited Announces Effective Date of Reverse Stock Split

BEIJING, Dec. 23, 2025 /PRNewswire/ — Elong Power Holding Limited (“Elong Power” or the “Company”) (Nasdaq: ELPW), a provider of high power battery technologies for commercial and specialty alternative energy vehicles and energy storage systems, today announced that it has resolved to effect a reverse stock split of the Company’s ordinary shares, with the split ratio set at 16-for-1. The reverse stock split was approved by the Company’s shareholders at a special meeting held on November 24, 2025. Elong Power’s Class A ordinary shares will begin trading on an adjusted basis, reflecting the reverse stock split, on December 26, 2026, under the existing ticker symbol “ELPW.” The new CUSIP number for the Company’s Class A ordinary shares will be G3016G111.

Upon the effectiveness of the reverse stock split, every sixteen shares of the Company’s issued and outstanding Class A ordinary shares as of the effective date will automatically be combined into one Class A ordinary share. This adjustment will reduce the total number of outstanding ordinary shares of Elong Power from approximately 61.3 million to approximately 3.8 million.

In conjunction with the reverse stock split, the Company also amended its Memorandum of Association to proportionately reduce the number of authorized shares for issuance and to adjust the par value of the post-reverse stock split ordinary shares to $0.00016 per share.

The reverse stock split is part of the Company’s efforts to bring its stock into compliance with the minimum bid price requirement for maintaining the listing of its Common Stock on the Nasdaq Capital Market. Nasdaq requires listed companies to maintain a minimum bid price of at least $1.00 per share to remain in compliance with its listing standards.

In addition, outstanding warrants and options will be adjusted on a proportionate basis or pursuant to the terms of such warrants and options in accordance with the reverse stock split. No fractional shares will be issued; instead, shareholders who would otherwise be entitled to a fractional share will have their entitlement rounded up to the nearest whole share.

Further details regarding the reverse stock split and the associated changes to the Company’s share capital can be found in Elong Power’s notice of annual general meeting, filed with the Securities and Exchange Commission on November 3, 2025.

About Elong Power

Elong Power Holding Limited, a Cayman Islands exempted company, is committed to the research and development, manufacturing, sales and service of high-power lithium-ion batteries for electric vehicles and construction machinery, as well as large-capacity, long-cycle lithium-ion batteries for energy storage systems. Elong Power is led by Ms. Xiaodan Liu, Elong Power’s Chairwoman and CEO.

Elong Power has a comprehensive product and technology system that includes battery cells, modules, system integration, and battery management system development, based on high-power lithium-ion batteries and battery system products for long-cycle energy storage devices. Elong Power offers advanced energy applications and full life cycle services. Its product portfolio includes products utilizing lithium manganese oxide and lithium iron phosphate, among others, to meet the needs of high-power applications and energy storage applications in various scenarios.

Forward-looking Statements

This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including statements regarding the benefits of the transaction, the anticipated timing of the transaction, the products offered by Elong Power and the markets in which it operates, and Elong Power’s projected future results. These forward-looking statements generally are identified by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will likely result,” and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this document, including, but not limited to: the ability of Elong Power to maintain the listing of its securities on Nasdaq; the fact that the price of Elong Power’s securities may be volatile due to a variety of factors, including changes in the competitive and highly regulated industries in which Elong Power operates; variations in performance across competitors; changes in laws and regulations affecting Elong Power’s business and changes in its capital structure; the ability to implement business plans, meet forecasts and other expectations; its need for substantial additional funds; the parties’ dependence on third-party suppliers; risks relating to the results of research and development activities, market and other conditions; its ability to attract, integrate, and retain key personnel; risks related to its growth strategy; risks related to patent and intellectual property matters; and the ability to obtain, perform under and maintain financing and strategic agreements and relationships. Accordingly, these forward-looking statements do not constitute guarantees of future performance, and you are cautioned not to place undue reliance on these forward-looking statements. Risks regarding Elong Power’s business are described in detail in Elong Power’s SEC filings which are available on the SEC’s website at www.sec.gov, including in Elong Power’s Shell Company Report on Form 20-F and Elong Power’s subsequent filings with the SEC. These forward-looking statements speak only as of the date hereof, and Elong Power expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions, or circumstances on which any such statement is based, except as required by law.

Elong Power Investor Contact
ir@elongpower.com 

Hyundai Motor Group Tops 2025 IIHS Top Safety Awards Underscoring Automotive Safety Leadership

  • Hyundai Motor Group secures a total of 21 TOP SAFETY PICK (TSP) and TOP SAFETY PICK+ (TSP+) awards in 2025 — the most of any automotive group for the second consecutive year
  • Hyundai Motor Company leads automakers with 10 TSP/TSP+ ratings, while Genesis earns six and Kia secures five
  • Flagship electric SUVs — Hyundai 2026 IONIQ 9 and 2025-26 Kia EV9 — demonstrate top-tier safety performance in IIHS evaluations
  • Results reflect strong performance under IIHS’s more stringent 2025 evaluation criteria, with a notable year-on-year increase in TOP SAFETY PICK+ ratings

SEOUL, South Korea, Dec. 23, 2025 /PRNewswire/ — Hyundai Motor Group (the Group) has reaffirmed its global leadership in automotive safety by securing a combined 21 TOP SAFETY PICK (TSP) and TOP SAFETY PICK+ (TSP+) awards in the 2025 Insurance Institute for Highway Safety (IIHS) evaluations ­— the highest total among automotive groups for the second consecutive year.

Hyundai IONIQ 9
Hyundai IONIQ 9

Of the 21 awarded models, 18 models achieved the highest 2025 TSP+ ratings, representing a significant increase from 12 TSP+ ratings in 2024 and underscoring the Group’s ability to meet increasingly demanding safety requirements.

Among the 2025 TOP SAFETY PICK+ recipients, Hyundai Motor Group’s flagship electric SUVs — including the all-new 2026 Hyundai IONIQ 9 and 2025-26 Kia EV9 — delivered strong performance across all IIHS evaluation categories, earning the top ‘good’ ratings in every applicable crashworthiness and crash-avoidance test.

The Group’s brands achieved the following results in 2025:

  • Hyundai Motor Company leads all automakers with eight TSP+ and two TSP ratings
  • Genesis received five TSP+ ratings and one TSP rating
  • Kia secured five TSP+ ratings

These results demonstrate the Group’s commitment to advancing safety technologies and meeting the industry’s most rigorous testing standards.

More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by Hyundai, Kia Global Media Center (kianewscenter.com), Genesis Newsroom

Greneta Unveils AI-Powered ‘Optimizer 2.0’ at CES 2026; Solves Spatial Computing’s Data Bottleneck with 99.6% Compression

  • Named a CES 2026 Innovation Award Honoree, Greneta’s new engine transforms massive industrial 3D assets into streamable formats for Digital Twins and Physical AI
  • Live demonstrations available at Eureka Park, Korea Pavilion (Booth #62501)

LAS VEGAS, Dec. 23, 2025 /PRNewswire/ — As industries race to adopt spatial computing and Physical AI, they face a critical infrastructure bottleneck: high-fidelity 3D assets are simply too heavy to stream efficiently. Greneta, a deep-tech startup specializing in 3D infrastructure, today announced the global launch of Greneta Optimizer 2.0 at CES 2026. This solution reduces 3D data size by up to 99.6% while preserving the geometric precision required for industrial and medical applications.

Greneta Optimizer 2.0, CES 2026 Innovation Award Honoree in Content & Entertainment
Greneta Optimizer 2.0, CES 2026 Innovation Award Honoree in Content & Entertainment

While traditional compression tools often degrade visual quality—acting like the “MP3 of 3D”—Greneta’s solution maintains professional-grade fidelity. This technological achievement has been recognized by the Consumer Technology Association (CTA), which named Greneta a CES® 2026 Innovation Award Honoree in the Content & Entertainment category.

Bridging the Gap for the Industrial Metaverse

“The era of waiting for 3D files to load is over,” said Tae Woong Kim, CEO of Greneta. “Whether it is a digital twin of a factory or a training simulation for robotics, data weight is the enemy of scale. Optimizer 2.0 removes that friction instantly.”

Key capabilities

  • Extreme Optimization: Compressing Gigabyte-scale CAD and LiDAR scans into Megabytes in seconds, enabling real-time streaming on mobile XR devices.
  • AI-Driven Restoration: Automatically repairing mesh errors and holes common in 3D scans, a critical feature for establishing ‘Physical AI’ environments.
  • Enterprise Compatibility: Seamless integration with major platforms including Unreal Engine, Unity, and NVIDIA Omniverse via plugin architecture.

Validated by Industry Leaders

Greneta is also a member of NVIDIA Inception, a program that nurtures startups revolutionizing industries with technological advancements.

Visit Us at Eureka Park

Greneta invites journalists, investors, and industry partners to witness the comparison between original and optimized data.

  • Location: Venetian Expo, Eureka Park, Korea Pavilion
  • Booth: #62501

About Greneta

Greneta is a spatial data optimization company dedicated to making 3D content accessible on any device. By combining proprietary AI quantization with mesh restoration technology, Greneta serves the manufacturing, construction, and entertainment sectors. For more information, visit https://greneta.ai/

Highway Holdings Plans to Acquire 51% of Regent-Feinbau Adermann GmbH

HONG KONG, Dec. 23, 2025 /PRNewswire/ — Highway Holdings Limited (Nasdaq: HIHO, the “Company” or “Highway Holdings”) today announced it has signed a letter of intent (“LOI”) with LeMALe Beteiligungs-GmbH (“LeMaLe” or “Seller”) to acquire 51% of German-based Regent-Feinbau Adermann GmbH (“Regent-Feinbau”) primarily for cash and a smaller amount of the Company’s unregistered shares.

The proposed acquisition, which targets a close by the end of March 2026, remains subject to the completion of due diligence, negotiation and execution of a definitive purchase agreement, and satisfaction of customary closing conditions. There can be no assurance that the parties will enter into a definitive agreement or that any transaction will be consummated.

Founded in 1949, Regent-Feinbau is a certified manufacturing specialist (IATF 16949, ISO 9001, ISO 14001) for precision sheet metal components and welded assemblies made of aluminum, steel, and copper. With decades of experience and vertically integrated capabilities, Regent-Feinbau delivers high-quality, scalable solutions for demanding applications – from laser-cut parts to fully assembled functional units. Regent-Feinbau’s core competencies include: Laser cutting and bending (efficient, high-precision processing using CNC press brakes and automated systems); Forming technology (flexible production with extender presses and CNC-controlled bending for complex geometries); Component assembly (complete systems with integrated fastening and joining processes); and Advanced welding (including drawn arc, projection, spot, and robotic welding, ensuring strong, repeatable joints across a wide range of materials). Regent-Feinbau primarily serves OEMs directly, while also supporting Tier 1 suppliers with reliable, production-ready components and assemblies across the automotive, commercial vehicle, aerospace, and industrial sectors.

Roland Kohl, chairman, president and chief executive officer of Highway Holdings, commented, “We are extremely excited to have signed a letter of intent to acquire 51% of Regent-Feinbau. The acquisition is part of our short and long-term strategy to reinvigorate our OEM business, which has an urgent need to replace customers whose revenue contribution has declined or halted due to the global business challenges entering and exiting COVID. Regent-Feinbau’s experience with automotive customers and that company’s excellent capabilities, which allows them to be a Tier 1 supplier to companies such as AMG Mercedes Benz, will have a lot of value for our Chinese metal component division, Nissin Shenzhen, in targeting the Chinese automotive market.

The Chinese automotive market is one of the automotive markets left with a positive growth rate, which according to third party estimates currently is about $660 billion with a projected growth rate of over 2% over the next 5 years. The percentage of sheet metal in a car is estimated to be about 8% to 12%. The average sheet metal component business is therefore roughly $50 billion per year, with a 2% growth rate or about $1 billion per year.

While Highway Holdings’ history in China spans over 35 years, the Company has never directly targeted the local Chinese market, with the exception of supporting our international OEM customers that have a local Chinese presence. We view the Regent-Feinbau transaction as a significant opportunity, as prior to a Regent-Feinbau acquisition we could not offer thick sheet metal cutting, bending and welding to potential customers. Regent-Feinbau will expand our portfolio and add these sought after capabilities and experience to our company.”

Mr. Kohl added, “Regent-Feinbau’s business in Europe is also expected to grow with the help of our know-how and experience, allowing it to approach high volume component businesses they could not previously target because of a lack of resources. These synergies are highly valuable, which is why we are so excited about the potential positive impact of this acquisition.”

“Importantly, Regent-Feinbau is only the first step in our M&A strategy. We are currently evaluating  additional transactions in Germany that we have identified and evaluated over the last 24 months.”

“We believe that we have a very strong financial foundation to acquire Regent-Feinbau and potentially other targets, with substantially no debt and approximately $5.3 million in cash and cash equivalents, representing approximately US$1.20 cash per share.”

About Highway Holdings Limited

Highway Holdings is an international manufacturer of a wide variety of quality parts and products for blue chip equipment manufacturers based primarily in Germany. Highway Holdings’ administrative offices are located in Hong Kong and its manufacturing facilities are located in Yangon, Myanmar, and Shenzhen, China. For more information visit website www.highwayholdings.com

Except for the historical information contained herein, the matters discussed in this press release are forward-looking statements which involve risks and uncertainties, including but not limited to economic, competitive, governmental, political and technological factors affecting the company’s revenues, operations, markets, products and prices, and other factors discussed in the company’s various filings with the Securities and Exchange Commission, including without limitation, the company’s annual reports on Form 20-F.

Senhwa Biosciences Highlights AI-Validated Oncology Platform and Strategic Clinical Collaborations Targeting Next-Generation Immuno-Oncology products at Its 2025 Annual Investor Conference

TAIPEI and SAN DIEGO, Dec. 23, 2025 /PRNewswire/ — Senhwa Biosciences, Inc. (TPEx: 6492), a clinical stage companies focusing on development of first-in-class therapeutics for oncology, rare diseases, and infectious diseases, today outlined continued progress across its AI-enabled drug development platform at its 2025 annual investor conference, reinforcing its strategic position as the global immuno-oncology landscape enters a period of generational transition.

Global blockbuster immune-oncology products now face major patent expirations before 2030 pharmaceutical companies are either actively developing or acquiring next-generation assets that are highly combinable, scalable across multiple tumor types with potential of becoming treatment standard in different types of cancers. Senhwa is addressing this demand through an integrated strategy that combines artificial intelligence validation, precision clinical development, and global pharmaceutical partnerships.

Recently, Google DeepMind applied its latest C2S-Scale biological AI model to analyze more than 4,000 drug candidates and identified Senhwa’s lead compound Silmitasertib (CX-4945) as the most potential compound to revigorate immune system to combat with cancer. The study, supported by Google’s computing infrastructure, DeepMind’s proprietary AI models, and preclinical validation conducted by Yale University, demonstrated that CX-4945 significantly enhances tumor antigen presentation—an essential mechanism for improving immune recognition of cancer cells.

This independent third-party validation highlights the potential of CX-4945 as an immune-sensitizing agent and represents a notable milestone in the application of AI to oncology drug discovery. By addressing the long-standing challenge of immunologically “cold” tumors, which had limited response to immunotherapy, CX-4945 has a unique position in the rapidly expanding field of cold-to-hot tumor conversion.

In parallel, Senhwa continues to advance its clinical pipeline through strategic international collaboration. The company recently announced a clinical collaboration with BeOne Medicines to evaluate Senhwa’s lead candidate, Pidnarulex (CX-5461), in combination with BeOne’s commercially approved, best-in-class PD-1 inhibitor tislelizumab. The initial focus of the collaboration includes pancreatic cancer and advanced solid tumors, including immunotherapy-resistant melanoma.

CX-5461 is a first-in-class small molecule with a differentiated dual mechanism of action that stabilizes DNA G-quadruplex (G4) structures while inhibiting RNA polymerase I (Pol I). This dual activity induces replication stress in tumor cells and activates the innate immune cGAS–STING pathway, effectively converting immune-cold tumors into immune-active environments. Robust preclinical data supports the application of CX-5461 in enhancing the efficacy of existing immunotherapies and becoming the ideal candidate for combination therapy with immune-oncology products.

Senhwa believes this pathway-level, multi-target strategic approach positions CX-5461 as a potential next-generation treatment back bone in cancers where immunotherapy is used, rather than positioning the compound as a single-asset or indication-specific solution. This strategic positioning has attracted interest from global pharmaceutical companies seeking high value added platform assets, as reflected by ongoing and prior collaborations involving leading multinational partners.

Looking ahead, Senhwa expects multiple value-driving catalysts over the next one to three years, including clinical data readouts for CX-5461 and CX-4945, expansion of global partnerships, potential licensing collaborations, and increased visibility at major international medical conferences such as ASCO, AACR, and ESMO.

“Senhwa has transitioned beyond early-stage discovery and development into a company building a scalable, AI-validated oncology platform,” said the Company. “At a pivotal moment for immuno-oncology, we are focused on advancing differentiated science with the potential to create long-term value for patients, partners, and shareholders.”

Q101 Foundation Strikes Strategic Partnership with Global Classroom Technology Leader Mynd.ai to Jointly Expand the North American Market

SEATTLE, Dec. 23, 2025 /PRNewswire/ — The Q101 Foundation (“the Foundation”) is pleased to announce that it will enter into a Memorandum of Understanding (“MOU”) with Mynd.ai (NYSE American: MYND), a global leader in classroom technology. Under the MOU, Mynd.ai will act as the Foundation’s exclusive operating partner in North America, supporting user growth and ecosystem development for the Open Quest Academy (“Open-Q”).

The Q101 Foundation is a key ecosystem enabler and governance participant of the Open-Q educational ecosystem. Open-Q is committed to building an AI-driven, globally co-created and shared, decentralized educational ecosystem that empowers educators and learners worldwide.

Seattle-based Mynd.ai is a global leader in interactive technology offering best-in-class hardware and software solutions that help organizations create and deliver dynamic content; simplify and streamline teaching, learning, and communication; and facilitate real-time collaboration. Its award-winning interactive displays and software can be found in more than 1 million learning and training spaces across 126 countries. Its global distribution network of more than 4,000 reseller partners and its dedicated sales and support teams around the world enable Mynd.ai to deliver the highest level of service to its customers.

Pursuant to the MOU, Mynd.ai will operate the platform in North America by driving strategic promotion, ecosystem expansion, and user growth initiatives for the Open-Q ecosystem. In parallel, the Foundation will provide Mynd.ai with necessary support to ensure seamless end users experience in the region.

The mission of the Open-Q is to leverage technology to break down educational barriers, allowing learners and educators worldwide to collectively own the value they create. With the rollout of this strategic partnership with Mynd.ai, Open-Q is expected to achieve accelerated user growth in North America. Looking ahead, the Q101 Foundation will continue to pursue strategic collaborations with education governance bodies, educator and content creator communities, and education technology leaders in other regions to support the ecosystem’s global expansion and long-term development, of which Mynd.ai will be an integral part.