SINGAPORE, Oct. 27, 2025 /PRNewswire/ — Plug and Play APAC has partnered with the Italian Trade Agency (ITA) to support the international expansion of nine innovative Italian startups in the FinTech sector. As part of ITA’s Global Startup Program (GSUP), the cohort will embark on a four-week immersion trip to Singapore from October 21 to November 14, 2025.

The Italian Trade Agency and Plug and Play APAC kick off the 6th Global Startup Program in Singapore, connecting Italian Fintech startups with corporates and investors across Southeast Asia.

The program’s objective is to enable access to the Singaporean and Southeast Asian markets, enabling Italian startups to build strategic partnerships, strengthen organizational and technical capabilities, and position themselves for global growth. During their time in Singapore, the startups aim to validate their solutions in the Southeast Asian market, assess product-market fit, explore commercialization pathways, and establish conversations with corporates and investors.

Commenting on the launch of the fourth edition of the Global Startup Program in Singapore, Giorgio Calveri, Trade Commissioner of the Italian Trade Agency in Singapore, said:

“The Global Startup Program has become a key platform for showcasing Italian innovation, empowering our most promising entrepreneurs to compete and grow on the global stage. With the program being held in Singapore for the fourth time, we are proud to further strengthen Italy’s presence in major international hubs like Singapore, where FinTech plays a crucial role in shaping the future of business. By uniting our startups, global partners, and participation in the Singapore FinTech Festival through the Italian Pavilion, we are creating a bridge of opportunities that will enable Italian innovation to flourish worldwide.”

Plug and Play, a Silicon Valley-based global open innovation platform, has an established presence in Asia Pacific through its regional headquarters in Singapore. From this hub, Plug and Play connects corporates, startups, and venture capitalists within its vast ecosystem, driving cross-border collaboration and accelerating innovation across verticals.

A key highlight of this partnership will be the Italian Trade Agency Demo Day, held as part of the Plug and Play APAC Summit on 28 October 2025. The 9 startups will pitch their solutions to a global audience of corporates, investors, and ecosystem leaders. (https://www.plugandplayapac.com/apac-summit) They will also attend Singapore Week of Innovation and Technology (SWITCH) and the Singapore FinTech Festival (SFF).

“We’re proud to partner with the Italian Trade Agency to support Italian startups as they tap into the opportunities in Southeast Asia’s rapidly growing tech markets. Through this program, we’ll connect these innovators with our extensive network of corporates and investors, and our APAC Summit is the perfect stage to showcase their solutions. We look forward to strengthening cross-border innovation between Italy and Southeast Asia,” said Jupe Tan, Managing Partner, Plug and Play APAC.

The partnership underscores ITA and Plug and Play’s mutual commitment to bridging ecosystems, driving innovation, and creating opportunities for startups to scale beyond their local markets.

About Plug and Play

Plug and Play is the leading innovation platform, connecting startups, corporations, venture capital firms, universities, and government agencies. Headquartered in Silicon Valley, we’re present in 60+ locations across five continents. We offer corporate innovation programs and help our corporate partners in every stage of their innovation journey, from education to execution. We also organize startup acceleration programs and have built an in-house VC to drive innovation across multiple industries, where we’ve invested in hundreds of successful companies, including Dropbox, Guardant Health, Honey, Lending Club, N26, PayPal, and Rappi.

Our Asia Pacific headquarters was launched in Singapore in 2010, and we are now present in five cities in Southeast Asia with additional locations in China, Japan, Korea and India. We work closely with both the public and private sectors with programs, innovation initiatives, and startup investments across the region.

For more information, visit https://www.plugandplayapac.com

About Italian Trade Agency (ITA)

The Italian Trade Agency (ITA) is the governmental agency responsible for supporting the international expansion of Italian companies and promoting foreign investment into Italy. ITA plays a key role in enhancing the competitiveness of Italian businesses and facilitating their presence in global markets.

With a motivated and modern organization and a widespread network of overseas offices, ITA provides information, assistance, consulting, promotion, and training to Italian small and medium-sized businesses. Using the most modern multi-channel promotion and communication tools, it acts to assert the excellence of Made in Italy in the world.

The network. Through its headquarters in Rome, an office in Milan, and a global network of 69 offices and 18 local branches in 74 countries, linked to Italian embassies and consulates, the Italian Trade Agency provides information, assistance, promotion, training, and cooperation in the industrial, consumer goods and services sectors. The Italian Trade Agency collaborates with Italian Regions, Chambers of Commerce, Industry and Trade Associations and other public and private organisations.

For more information, visit https://www.ice.it/en/

Media Contact
press@pnptc.com 

BEIJING, Oct. 27, 2025 /PRNewswire/ — Langjiu, a leading Chinese baijiu brand, has held the “Chinese Langjiu, Welcoming the World” event in Italy from October 20 to 23.

During the event, Langjiu has participated in the Global Fashion Summit 2025 held in Milan, Italy, from October 21 to 22, as the exclusive liquor partner, highlighting the cultural charm of Chinese baijiu on the international stage.

This year’s summit focused on frontier topics in the global fashion industry, including artificial intelligence, creative innovation and sustainability, bringing together representatives from government institutions, industry associations and leading enterprises.

Luo Xi, deputy general manager of Langjiu’s International Business Department, said during the opening ceremony of the summit that although fashion and fine liquor belong to different worlds, both are “arts of time” that embody craftsmanship and inspiration.

“Fashion is the ultimate expression of individuality and aesthetics, while Qinghua Lang, one of Langjiu’s flagship products, represents the harmony of natural beauty and artisan spirit,” Luo said, adding that Langjiu hopes to inspire dialogue between global fashion and China’s ancient liquor-making traditions.

Following the summit, Langjiu hosted a themed cocktail reception featuring its Qinghua Lang, where guests enjoyed creative aperitif-style cocktails inspired by the blend of Eastern and Western traditions.

Italy marked the first stop of Langjiu’s “Chinese Langjiu, Welcoming the World” event. During its visit to Italy, the Langjiu team also traveled to Florence, the cradle of the Renaissance, for a dialogue with Marchesi Mazzei, a renowned Italian winery with over 650 years of history.

The two sides exchanged views on winemaking philosophies, regional terroir and brand internationalization. Francesco Mazzei, chairman of Marchesi Mazzei, praised Langjiu’s craftsmanship and vision, saying there will be great potential for cooperation.

Langjiu also hosted a “Qinghua Lang Night” gala tasting in Florence, attended by city government officials and local winery owners. Guests experienced the refined aroma and cultural depth of China’s sauce-aroma baijiu. During the event, Luo said Langjiu’s visit to Italy demonstrates the brand’s commitment to sharing Chinese baijiu culture globally and advancing the internationalization of traditional industries.

Following its debut in Italy, Langjiu’s global campaign will continue in France, the United States, Japan, Australia and other countries, using fine liquor as a bridge for dialogue, cultural exchange and cooperation.

Original link: https://en.imsilkroad.com/p/348034.html 

SHANGHAI and HONG KONG, Oct. 27, 2025 /PRNewswire/ — Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK), a leading innovative, commercial-stage global biotech company dedicated to discovering, developing and commercialising first-in-class and/or best-in-class medicines for autoimmune disease, solid tumors and hematological malignancies indications, today announced that the latest preclinical data of ATG-201 (CD19 x CD3 TCE) were presented in a Poster Presentation at the 2025 American College of Rheumatology (ACR) Annual Meeting, taking place from October 24th to October 29th in Chicago, IL, the United States. ATG-201 is a lead program developed using AnTenGager™, the company’s proprietary T-cell engager (TCE) platform which features “2+1” bivalent binding for low-expressing targets, steric hindrance masking, and proprietary CD3 sequences with fast on/off kinetics to minimize cytokine release syndrome (CRS) and enhance efficacy.

Details of the Poster Presentation:
ATG-201（CD19 x CD3 TCE）
Title: ATG-201, a Novel Steric Hindrance-based Masking CD19xCD3 T-cell Engager (TCE) for the Treatment of B Cell-related Autoimmune Diseases
Abstract Number: 0001
Session: (0001–0018) B Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster I
Date: Sunday, October 26
Time: 10:30 AM – 12:30 PM (Central Time)

Introduction: A “2+1” TCE Specifically Designed for Autoimmune Diseases

• CD19-targeted therapies, including CAR-T therapies and TCEs have demonstrated promising therapeutic potential in the treatment of autoimmune diseases. However, the clinical development of TCEs has been limited by suboptimal pharmacokinetics (PK), incomplete B cell depletion, and toxicity associated with CRS. To address these challenges, Antengene leveraged its proprietary AnTenGager^TM TCE platform to develop ATG-201, a novel “2+1” CD19 x CD3 TCE designed for B cell driven autoimmune diseases. ATG-201 incorporates steric hindrance masking technology and proprietary CD3 sequences with fast-on-fast-off kinetics, enabling effective B cell depletion with minimal risk of CRS.
• In this study, ATG-201 was evaluated through a series of in vitro and in vivo studies examining binding affinity, B cell depletion, cytokine release, anti-disease efficacy and developability. Safety and PK characteristics of ATG-201 were evaluated in mice and non-human primates (NHP).

Results: Overcoming Toxicities While Achieving Complete B Cell Depletion

• Cryo-electron microscopy (cryo-EM) analysis revealed that, in the absence of CD19 cross-linking, the CD3 binding site is sterically masked by the constant region of the CD19-targeting Fab arm. As a result, ATG-201 exhibits minimal binding to CD3+ T cell binding prior to CD19-crosslinking, and only activates T cells in the presence of CD19+ cells, thereby enabling precise, antigen-dependent immune activation.
• In in vitro studies, ATG-201 demonstrated stronger B cell depletion activity in peripheral blood mononuclear cells (PBMCs) derived from systemic lupus erythematosus (SLE) patient and healthy donors, while inducing substantially lower cytokine release compared to benchmark TCEs.
• In in vivo studies using CD34+ cells humanized NDG mice, a single dose of ATG-201 achieved complete and sustained B cell depletion in the blood, bone marrow and spleen, accompanied by reduced cytokine release.
• Furthermore, ATG-201 was shown to significantly reduce T cell exhaustion compared to first generation TCEs. In a co-culture study using primary T cells and NALM6 leukemia cells with serial antigen restimulation on Days 7 and 14, ATG-201 induced significantly lower expression of exhaustion markers PD-1 and Tim-3 as measured by flow cytometry. This reduced T-cell exhaustion underscores the advantages of the AnTenGager™ structure and novel CD3 binder, which limits both off-target and excessive on-target activation, preventing unnecessary prolonged T-cell stimulation.
• The mouse surrogate CD19 x CD3 TCE demonstrated potent efficacy in both the MOG-EAE and MRL-lpr SLE mouse models, confirming its robust therapeutic potential. In NHPs, the monkey surrogate of ATG-201 achieved deep and durable depletion of naïve B cells with a favorable safety profile, characterized by only a very mild and transient increase in cytokine levels. These findings further support the differentiated profile of ATG-201 as a next-generation T-cell engager designed to combine potent efficacy with superior safety.

Conclusion

• ATG-201 demonstrates CD19-dependent CD3 binding and activation, effectively inducing B cell depletion and disease suppression both in vitro and in vivo. With its favorable PK and safety profile, the data support further clinical evaluation of ATG-201 in B cell related autoimmune diseases. Antengene plans to advance ATG-201 into clinical development in Q4 2025.

About Antengene

Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK) is a global, R&D-driven, commercial-stage biotech company focused on developing first-in-class/best-in-class therapeutics for diseases with significant unmet medical needs. Its pipeline spans from preclinical to commercial stages and includes several in-house discovered programs, including ATG-022 (CLDN18.2 ADC), ATG-037 (oral CD73 inhibitor), ATG-101 (PD-L1 × 4-1BB bispecific antibody), ATG-031 (CD24-targeting macrophage activator), and ATG-042 (oral PRMT5-MTA inhibitor).

Antengene has also developed AnTenGager™, a proprietary T cell engager 2.0 platform featuring “2+1” bivalent binding for low-expressing targets, steric hindrance masking, and proprietary CD3 sequences with fast on/off kinetics to minimize cytokine release syndrome (CRS) and enhance efficacy. These characteristics support the platform’s broad applicability across autoimmune disease, solid tumors and hematological malignancies indications.

To date, Antengene has obtained 31 investigational new drug (IND) approvals in the U.S. and Asia, and submitted new drug applications (NDAs) in 11 Asia Pacific markets. Its lead commercial asset, XPOVIO® (selinexor), is approved in Mainland of China, Taiwan China, Hong Kong China, Macau China, South Korea, Singapore, Malaysia, Thailand, Indonesia and Australia, and has been included in the national insurance schemes in five of these markets (Mainland of China, Taiwan China, Australia, South Korea and Singapore).

Forward-looking statements

The forward-looking statements made in this article relate only to the events or information as of the date on which the statements are made in this article. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect. In this article, statements of, or references to, our intentions or those of any of our Directors or our Company are made as of the date of this article. Any of these intentions may alter in light of future development. For a further discussion of these and other factors that could cause future results to differ materially from any forward-looking statement, please see the other risks and uncertainties described in the Company’s Annual Report for the year ended December 31, 2024, and the documents subsequently submitted to the Hong Kong Stock Exchange.

For more information, please contact:

Investor Contacts: 
Donald Lung
E-mail: donald.lung@antengene.com 

BD Contacts:
Ariel Guo
E-mail: ariel.guo@antengene.com

SINGAPORE, Oct. 27, 2025 /PRNewswire/ — YeePay, a leading digital transaction service provider for the global aviation and travel ecosystem, made a strong appearance at ITB Asia 2025, Asia’s largest B2B travel trade show, held from October 15–17 at the Sands Expo & Convention Centre in Singapore.

Under the theme “Exploring Trends and Innovations Shaping the Future of Travel,” this year’s ITB Asia gathered over 1,900 exhibitors and 18,500 industry professionals from the Asia-Pacific, Europe, the Middle East, Africa, and the Americas. The event served as a major platform for global collaboration, innovation, and industry exchange.

As an exhibitor, YeePay presented its One-Stop Global Enterprise Account Transaction Solution, designed to address key challenges faced by airlines, OTAs, and travel service providers in managing cross-border payments. The solution enables businesses to handle global collection, disbursement, and FX management seamlessly through a single account — offering lower costs, better rates, and faster settlements.

“ITB Asia marks our third consecutive year participating in this global event,” said Yu Chen, Co-Founder of YeePay. “We believe payments are more than just a means of transferring funds — they are the bridge that connects global tourism resources. Through professional and compliant transaction services, YeePay aims to help Chinese cultural and tourism organizations expand internationally while enabling overseas travel enterprises to enter the Chinese market with ease.”

Backed by 22 years of industry expertise and technological innovation, YeePay has built an intelligent global transaction network covering over 200 countries and regions and supporting more than 60 currencies. With its smart FX engine, global account system, and intelligent fund routing infrastructure, YeePay provides clients with compliant fund management, optimized FX services, and tailored transaction solutions that align with diverse business needs.

By integrating financial technology with cultural tourism, YeePay remains committed to powering the innovation, recovery, and sustainable growth of the global travel economy.

About YeePay

Founded in 2003, YeePay is one of China’s leading licensed third-party payment service providers, regulated by the People’s Bank of China. YeePay serves more than one million enterprise clients across industries including travel, retail, fintech, cross-border trade, and digital government services.

Learn more at global.yeepay.com.
Follow us on LinkedIn

Business Contact:
Lingshu Meng 
lingshu.meng@yeepay.com

GUANGZHOU, China, Oct. 27, 2025 /PRNewswire/ — At Phase 2 of the 138th Canton Fair, the Gardening Products and Weaving, Rattan & Iron Products sections are attracting strong interest for their focus on practical aesthetics, merging everyday functionality with artistry and sustainable design. Exhibitors are demonstrating how craftsmanship and green innovation can elevate the beauty and usability of modern living spaces.

A leading exhibitor in eco-friendly garden supplies has transformed nearly its entire booth into a display of new products, with 90% of the showcased items being first-time launches. Among the highlights is an innovative self-watering, root-protection flowerpot featuring a patented plant breathing system. This breakthrough design redefines conventional planting methods by enabling the flowerpot to absorb and regulate water automatically, preventing root rot and ensuring consistent hydration without manual intervention. Another centerpiece, the “unbreakable” Jun porcelain flowerpot, combines traditional ceramic artistry with modern polymer technology. By integrating recycled marine plastics into its composition, the design merges heritage craftsmanship with advanced material science, reflecting a broader industry shift toward sustainability and functional aesthetics.

Another exhibitor is turning agricultural by-products into valuable decorative items. Through circular design principles, discarded materials such as tea and mulberry branches are repurposed into high-end crafts, achieving full reuse of raw materials and significantly reducing agricultural waste. Among its featured products, the Tea Branch Art Frame Series and Color Wood Inlay Ornaments have attracted attention for their fusion of natural textures, Chinese design motifs, and Western decorative sensibilities—a combination increasingly favored by global buyers.

In the same section, a long-time Canton Fair participant is highlighting innovation in eco-conscious storage solutions. By combining traditional hand-weaving with modern aesthetics, the company introduces over 1,000 new designs each year using recyclable and certified materials. Its integration of natural fibers, textiles, and recycled plastics reflects a continued commitment to low-carbon manufacturing and sustainable living.

Through these innovations, the Canton Fair underscores its pivotal role in promoting eco-conscious design and practical beauty in everyday living. As global consumers embrace sustainable and artisanal products, exhibitors are redefining the intersection between functionality, craftsmanship, and environmental responsibility.

To register the 138th Canton Fair, please click https://buyer.cantonfair.org.cn/register/buyer/email?source_type=16.  

SINGAPORE and AUSTIN, Texas, Oct. 27, 2025 /PRNewswire/ — Augmentus, the Singapore-based pioneer in AI-robotics and adaptive automation, today announced a strategic investment from Applied Ventures, LLC, the venture capital arm of Applied Materials, Inc. This investment marks a significant milestone in Augmentus’ mission to enable intelligent, autonomous robotics for high-mix, high-variability manufacturing across the globe.

At the heart of Augmentus’ innovation is its flagship AutoPath™ robotics stack, designed to be both the eyes and the brains of industrial robots. The system combines advanced 3D vision with adaptive intelligence to give robots an unprecedented ability to perceive, understand, and act. By generating highly precise and comprehensive point clouds, AutoPath allows robots to capture even the most intricate geometries and surface deviations. These insights are then translated into dynamic, real-time path generation, enabling robots to adjust motion on the fly and deliver consistent accuracy across complex, high-mix environments.

This convergence of perception and cognition creates a true no-code intelligence layer, eliminating the reliance on expert programming and manual robot teaching. Robots can now be deployed and reconfigured in minutes, not hours or days, transforming them from rigidly pre-programmed machines into adaptive collaborators capable of learning from and responding to the variability of real-world production.

“Our vision is to enable factories to adapt as quickly as the world changes,” said Daryl Lim, Co-Founder & CEO of Augmentus. “With the support of Applied Ventures, we are accelerating toward a future where robots can truly see, understand, and act — bringing agility, precision, and resilience to global manufacturing.”

“At Applied Ventures, we invest in innovative companies that are driving breakthroughs in AI, automation and advanced manufacturing,” said Abhishek Sud, Senior Investment Director at Applied Ventures, LLC. “Our investment in Augmentus underscores the rising importance of adaptive robotics in enabling efficiency and resilience in a rapidly evolving industrial landscape.”

About Augmentus

Augmentus is a Deeptech robotics software company headquartered in Singapore with U.S. operations in Austin, Texas. Its no-code, AI-powered platform integrates 3D scanning, automatic toolpath generation, and adaptive robotic motion — enabling manufacturers to automate complex processes with speed and flexibility. Deployed across aerospace, automotive, energy, and heavy industries, Augmentus allows robots to adapt to real-world variability, cutting setup times from hours to minutes. Learn more at www.augmentus.tech.

About Applied Ventures, LLC

Applied Ventures, LLC, the venture capital arm of Applied Materials, Inc., invests in innovative technology companies globally that are poised to deliver high growth and exceptional strategic and financial returns. For more than a decade, Applied Ventures has invested in startups globally, that are pioneering innovations in semiconductor and display technologies, robotics, advanced manufacturing, high-performance computing, smartphones, augmented and virtual reality, AI/ML, fab automation software, sensors, advanced materials, and cleantech. Learn more at www.appliedventures.com. 

CONTACT: Juanne Tan, marketing@augmentus.tech