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EVOLVE Partners with Pangaea Connectivity (1473.HK) to Power the Future of Real-World Asset Tokenisation

HONG KONG, Oct. 8, 2025 /PRNewswire/ — Real-world asset (RWA) tokenisation — turning physical and income-generating assets into tradable digital tokens — is emerging as one of the most transformative shifts in global finance. While many platforms promise tokenisation, the critical challenge lies in bridging the gap between the physical world and blockchain. Pangaea Connectivity Technology Limited (“Pangaea Connect”, stock code: 1473.HK), in strategic collaboration with Mile Green Company Limited (“Mile Green“), provides a concrete solution to this challenge, combining advanced AIoT-driven visibility with a comprehensive RWA ecosystem, now extended through the Velo Protocol and Lightnet.

Why IoT is the Foundation for Credible RWA

For an asset to be credibly tokenised on-chain, it must first be able to be “seen” and continuously monitored in real time. Without IoT, investors face significant risks: dependence on intermediaries, delayed financial reporting, and opaque collateral conditions. This creates information asymmetry and undermines trust in asset-backed finance.

Pangaea Connect contributes to address this bottleneck through its extensive experience in HPC, AIoT, and connectivity solutions which form the foundational digital infrastructure required for reliable, high-speed data transmission in blockchain-based tokenisation. This foundation ensures continuous, intelligent data flow to monitor and preserve the value and legitimacy of tokenised asset, supporting its marketplace credibility. From solar farms and EV chargers reporting live energy output, to goods-in-transit verified by GPS and condition sensors, to high-value machinery monitored in real time, Pangaea Connect orchestrates connectivity technologies and solutions to provides verifiable data that supports yield, valuation, and collateral integrity. This capability not only enhances transparency and traceability but also enables smart contracts to automate dividend payments, loan terms, and ESG impact validation.

EVOLVE: A Comprehensive RWA Ecosystem, Powered by Pangaea IoT

Mile Green, through its EVOLVE platform, has proven its ability to commercialize RWA tokenisation, EVOLVE integrates top-tier blockchain networks, licensed financial institutions, fiat-crypto payment providers, legal advisors, independent valuers, and ESG consultants into a seamless end-to-end platform. With Pangaea’s IoT backbone ensuring real-time monitoring, EVOLVE offers a complete environment where RWAs can be reliably tracked, tokenised, and traded with confidence.

The Path Forward: Building an Institutional-Grade Tokenisation Network

Building on this foundation, EVOLVE is taking the lead in building the next generation of RWA infrastructure, with Pangaea Connect contributing the alignment of the critical technology. Strengthened by advanced AIoT-enabled connectivity that links real-world data with blockchain settlement, this integrated approach establishes the transparency, scalability, and institutional-grade reliability required to transform RWAs into a credible and investable asset class, with foreseeable potentials:

  • Develop Tokenised Assets Backed by Real-Time IoT Data: Creating a new class of transparent, data-verified digital assets.
  • Create De-Risked Financial Products: Leveraging verifiable asset data for supply chain finance and asset-backed lending with unprecedented transparency.
  • Integrate IoT Platforms with Blockchain Settlement: Merging real-world monitoring data with Velo’s PayFi network and Lightnet’s compliant payment rails for seamless, scalable, and transparent transactions between fiat and digital assets.
  • Participate in the Digital Asset Ecosystem: Exploring Opportunities to launch a digital asset treasury program such as Velo tokens, strengthening institutional-grade participation and expanding Asia’s digital finance infrastructure.

Through the combined expertise and resourced of Mile Green, Velo Protocol, Lightnet, and Pangaea Connect, EVOLVE is setting a new benchmark for the RWA market. By unlocking transparency, enhancing risk management, and ensuring verifiable value creation, the collaboration is providing the foundation to scale tokenisation from isolated pilots into a global, investable, and sustainable ecosystem.

Gorilla Technology Launches Quantum-Safe SD-WAN to Future-Proof National AI and Network Infrastructure

– Establishes Gorilla Intelligent Network Director, which is among the industry’s first PQC-enabled SD-WAN solutions

– Designed in alignment with U.S. CNSA 2.0 and emerging global post-quantum security standards

London, United Kingdom – (Newsfile Corp. – October 8, 2025) – Gorilla Technology Group Inc. (NASDAQ: GRRR) (“Gorilla” or the “Company”), a global solution provider in Security Intelligence, Network Intelligence, Business Intelligence and IoT technology, today announced the launch of an industry first, post-quantum cryptography (PQC) Quantum-Safe Software-Defined Wide Area Network (SD-WAN) Initiative. This enhanced security offering will be housed under the flagship Gorilla Intelligent Network Director platform.

The Gorilla Intelligent Network Director performs a hybrid key exchange using both Elliptic-Curve Diffie-Hellman (ECDH) and Kyber algorithms, providing crypto-agility and long-term confidentiality even under potential quantum threats. Simultaneously, Dilithium-based digital signatures secure node authentication and control-plane integrity, protecting both orchestration and data channels. The result is a quantum-resistant connectivity layer designed for hybrid, multi-cloud and sovereign network environments that underpin national AI and digital infrastructure. Notably, this initiative integrates NIST-approved PQC algorithms – CRYSTALS-Kyber for key exchange and CRYSTALS-Dilithium for digital signatures – into the secure communications framework of the Gorilla Intelligent Network Director.

“In today’s world, quantum-safe networking is an operational imperative,” said Dr. Rajesh Natarajan, Chief Technology Officer at Gorilla Technology. “With the Gorilla Intelligent Network Director, we are embedding post-quantum resilience directly into the connectivity fabric that powers AI platforms and sovereign clouds. This initiative puts important national security and digital sovereignty measures in place, and positions Gorilla to deliver on a key priority for governments around the globe.”

The U.S. government’s planned rollout of CNSA 2.0 (Commercial National Security Algorithm Suite 2.0) between 2025 and 2030 sets a global precedent for cryptographic modernisation. Gorilla’s alignment with these standards ensures that every deployment of the Gorilla Intelligent Network Director will meet or exceed post-quantum-resilient security expectations, achieving readiness for the 2030-2033 compliance horizon.

The quantum-safe evolution of the Gorilla Intelligent Network Director builds on Gorilla’s multi-billion-dollar AI and data centre initiatives, globally – including the recently signed US$1.4 billion Southeast Asia network with Freyr Technology AI and ongoing public-safety and digital-infrastructure deployments in Thailand and Taiwan. It extends the company’s post-quantum security deployments for government networks in MENA and Thailand, which establishes a standards-based architecture for cryptographic agility. These offerings are designed to generate multi-year recurring revenue as governments and enterprises undertake their post-quantum transitions.

Customers adopting the Gorilla Intelligent Network Director gain:

  • Crypto-Agility – Seamless upgrade paths as PQC standards evolve
  • End-to-End Protection – Quantum-safe encryption from data centre core to edge device
  • Regulatory Readiness – Compliance with CNSA 2.0, NIST SP 800-208 and UK NCSC transition frameworks

“Our mission is to safeguard and harden every connection by default,” added Dr. Natarajan. “As AI platforms become the new critical infrastructure, the Gorilla Intelligent Network Director ensures that data, control and identity remain quantum-safe from the core to the edge.”

To accelerate adoption, Gorilla is establishing Quantum-Safe Readiness Labs in Taiwan and India, enabling governments, telecom operators and enterprises to validate hybrid key exchange, simulate quantum migration strategies and adopt reference blueprints for secure national network transformation.

About Gorilla Technology Group Inc.
Headquartered in London U.K., Gorilla is a global solution provider in Security Intelligence, Network Intelligence, Business Intelligence and IoT technology. We provide a wide range of solutions, including Smart City, Network, Video, Security Convergence and IoT, across select verticals of Government & Public Services, Manufacturing, Telecom, Retail, Transportation & Logistics, Healthcare and Education, by using AI and Deep Learning Technologies.

Our expertise lies in revolutionizing urban operations, bolstering security and enhancing resilience. We deliver pioneering products that harness the power of AI in intelligent video surveillance, facial recognition, license plate recognition, edge computing, post-event analytics and advanced cybersecurity technologies. By integrating these AI-driven technologies, we empower Smart Cities to enhance efficiency, safety and cybersecurity measures, ultimately improving the quality of life for residents.

For more information, please visit our website: Gorilla-Technology.com.

Forward-Looking Statements:
This press release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Gorilla’s actual results may differ from its expectations, estimates and projections and consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “might” and “continues,” and similar expressions are intended to identify such forward-looking statements. These forward-looking statements include, without limitation, statements regarding our beliefs about future revenues, our ability to convert our pipeline, our ability to and the circumstances under which we would reduce our debt, our ability to attract the attention of customers and investors alike, our expansion into southeast Asia, Gorilla’s largest projects and ability to win additional projects and execute definitive contracts related thereto, along with those other risks described under the heading “Risk Factors” in the Form 20-F Gorilla filed with the Securities and Exchange Commission (the “SEC”) on April 30, 2025 and those that are included in any of Gorilla’s future filings with the SEC. These forward-looking statements involve significant risks and uncertainties that could cause actual results to differ materially from expected results. Most of these factors are outside of the control of Gorilla and are difficult to predict. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those indicated or anticipated by such forward-looking statements. Readers are cautioned not to place undue reliance upon any forward-looking statements, which speak only as of the date made. Gorilla undertakes no obligation to update forward-looking statements to reflect events or circumstances after the date they were made except as required by law or applicable regulation.

Public Relations Contact:
Samantha Dowd
Prosek Partners
GRRR@prosek.com

Investor Relations Contact:
Dave Gentry
RedChip Companies, Inc.
1-407-644-4256
GRRR@redchip.com

The issuer is solely responsible for the content of this announcement.

NYSE Content Advisory: Pre-Market Update + The AW Playmaker Awards Take the Stage at 11 Wall Street

NEW YORK, Oct. 8, 2025 /PRNewswire/ — The New York Stock Exchange (NYSE) provides a daily pre-market update directly from the NYSE Trading Floor. Access today’s NYSE Pre-market update for market insights before trading begins. 

 

NYSE Content Advisory: Pre-Market Update + The AW Playmaker Awards Take the Stage at 11 Wall Street

Ashley Mastronardi delivers the pre-market update on October 8th

  • Stocks are fractionally higher Wednesday as traders await minutes from the Federal Reserve’s latest meeting. The gains come after the S&P 500 snapped a seven-day winning streak.
  • The Federal Reserve meeting minutes should provide clues this afternoon on the path forward for interest rates, while investors keep their focus on long-term opportunities.
  • Fanatics Advertising will present the Advertising Week Playmaker Awards at the NYSE this evening. They spotlight innovators in sports that are rewriting the rules of engagement.

Opening Bell
Empire State Realty Trust (NYSE: ESRT) celebrates the 47th Annual Empire State Building Run-Up – Presented by NYU Langone Health

Closing Bell
Nuvation Bio (NYSE: NUVB) celebrates the approval of its first medicine in June and transforming into a commercial-stage company with a promising pipeline

Click here to download the NYSE TV App

Video – https://mma.prnasia.com/media2/2791509/NYSE_Market_Update_October_8.mp4 

 

First Phosphate Thanks Canada’s Minister of Energy and Natural Resources for Visiting Saguenay-Lac-St-Jean, Quebec, Canada

This ministerial visit highlights the strategic importance of high-purity phosphate for the North American energy transition


Saguenay, Quebec – Newsfile Corp. – October 8, 2025 – First Phosphate Corp. (CSE: PHOS) (OTCQX: FRSPF) (FSE: KD0) (“First Phosphate” or the “Company”) was pleased to welcome the Honourable Timothy Hodgson, Canada’s Minister of Energy and Natural Resources, MP Claude Guay, Parliamentary Secretary to the Minister of Energy and Natural Resources, and Members of Parliament (“MPs”) Mario Simard and Richard Martel, to the planned site of its future phosphoric acid plant at Port Saguenay in the Saguenay-Lac-Saint-Jean region of Quebec, Canada on Saturday, October 4, 2025, during Minister Hodgson and Parliamentary Secretary Guay’s visit to the region.

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To view an enhanced version of this graphic, please visit:
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“We were honoured to welcome Minister Hodgson, Parliamentary Secretary Guay and others to Saguenay-Lac-Saint-Jean. This visit demonstrates the strategic importance of high-purity igneous phosphate for the future of Canada -a key resource for Canada’s energy transition and prosperity,” said Armand MacKenzie, President of First Phosphate.

This ministerial visit highlights the potential role of First Phosphate’s high-purity igneous phosphate project in Canada’s energy transition and in the sustainable development of a North American supply chain for lithium iron phosphate (“LFP”) batteries. These batteries are essential to the future of North America’s energy storage, mobility, data centre, robotics, and defence sectors.

Mr. Guay is Member of Parliament for LaSalle-Émard-Verdun and Parliamentary Secretary to the Minister of Energy and Natural Resources. Mr. Simard is Member of Parliament for Jonquière and Vice-Chair of the Standing Committee on Natural Resources, Canada. Mr. Martel is Member of Parliament for Chicoutimi-Le Fjord and member of the Standing Committee on Natural Resources, Canada.

Mr. Guay stated: “As Parliamentary Secretary to the Minister of Energy and Natural Resources, and a Quebec MP, I know this province and this country has what we need to leverage our natural resources into the strongest economy in the G7. Quebec has long been a leader in clean tech and sustainable mining, and I look forward to the Saguenay region continuing to show leadership and innovation.”

Mario Simard stated: “I am delighted with the constructive discussions we had today regarding the First Phosphate project. This is a promising initiative, and today’s meeting follows the presentation made to the Minister last June in Ottawa. The phosphate industry is on the right track and is fully in line with our region’s economic diversification objectives. Now we must continue our work to ensure that the project can benefit from federal programs supporting critical minerals.”

Richard Martel added: “I support the development of First Phosphate, a company that sees beyond simply operating a mine. It is this VISION that will enable us to develop phosphate and our critical minerals to their full potential.”

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To view an enhanced version of this graphic, please visit:
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About First Phosphate Corp
First Phosphate (CSE: PHOS) (OTCQB: FRSPF) (FSE: KD0) is a mineral development company dedicated to producing high-purity phosphate for the LFP battery industry. The Company’s vertically integrated approach connects sustainable phosphate mining in Quebec with North American battery supply chains, targeting the energy storage, data center, robotics, mobility, and defense sectors. First Phosphate’s flagship Bégin-Lamarche Property in Saguenay-Lac-Saint-Jean is one of North America’s rare igneous phosphate resources, yielding high-purity phosphate with minimal impurities.

For additional information, please contact:
Armand MacKenzie
President
armand@firstphosphate.com
Tél : +1 (514) 618-5289

Investor Relations: investor@firstphosphate.com
Media Relations: media@firstphosphate.com
Website: www.FirstPhosphate.com

Follow First Phosphate:
X : https://x.com/FirstPhosphate
LinkedIn : https://www.linkedin.com/company/first-phosphate

Forward-Looking Information and Cautionary Statement
This release includes certain statements that may be deemed “forward-looking information”. Any statement that discusses predictions, expectations, beliefs, plans, projections, objectives, assumptions, future events or performance (often but not always using phrases such as “expects”, or “does not expect”, “is expected”, “anticipates” or “does not anticipate”, “plans”, “budget”, “scheduled”, “forecasts”, “estimates”, “believes” or “intends” or variations of such words and phrases or stating that certain actions, events or results “may” or “could”, “would”, “might” or “will” be taken to occur or be achieved) are not statements of historical fact and may be forward-looking information. In particular, this press release contains forward-looking information relating to, among other things, the Company’s planned exploration and production activities; the properties and composition of any extracted phosphate; the Company’s plans for vertical integration into North American supply chains, the Company’s plans relating to the design, build, operation and maintenance of the Bégin-Lamarche Phosphate Mine (and the possibility of eventual economic extraction of minerals from therefrom); the Company’s entering into of a definitive land lease for planned site of its future phosphoric acid plant at Port Saguenay and the achievement of preconditions thereto; the achievement and completion of all required steps, including, without limitation, access to financing, satisfactory feasibility studies, and receipt of regulatory and environmental approvals to build and operate a phosphoric acid plant. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include development and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. These statements are based on a number of assumptions including, among other things, assumptions regarding general business and economic conditions; there being no significant disruptions affecting the activities of the Company or inability to access required project inputs; permitting and development of the projects being consistent with the Company’s expectations; the accuracy of the current mineral resource estimates for the Company and results of metallurgical testing; certain price assumptions for P2O5 and Fe2O3; inflation and prices for Company project inputs being approximately consistent with anticipated levels; the Company’s relationship with First Nations and other Indigenous parties remaining consistent with the Company’s expectations; the Company’s relationship with other third party partners and suppliers remaining consistent with the Company’s expectations; government relations and actions being consistent with Company expectations. Investors are cautioned that any such statements are not guarantees of future performance and actual results or developments may differ materially from those projected in the forward-looking statements. Accordingly, readers should not place undue reliance on the forward-looking information contained in this press release. The Company does not assume any obligation to update or revise its forward-looking statements, whether because of new information, future events or otherwise, except as required by applicable law. All forward-looking information contained in this release is qualified by these cautionary statements.

The issuer is solely responsible for the content of this announcement.

About First Phosphate Corp.

Public Interest Registry Unveils Winners of 7th Annual .ORG Impact Awards at DC Ceremony Hosted by Grammy-Award Winning Artist Common

The Fund for Congolese Women named 2025 .ORG of the Year, selected from nearly 3,000 applicants from more than 120 countries

WASHINGTON, Oct. 8, 2025 /PRNewswire/ — Public Interest Registry (PIR), the people behind the .ORG domain, announced the winners of the 2025 ORG Impact Awards, an annual celebration recognizing and rewarding outstanding mission-driven individuals and organizations from around the world for their positive contributions to society. The seven winners — selected from nearly 3,000 applicants from more than 120 countries — were announced live at the awards ceremony, which took place on Tuesday in Washington, D.C.

Public_Interest_Registry_Common
Public_Interest_Registry_Common

Common, the first rapper to win a Grammy, Oscar and Emmy award and star of the Apple TV+ show Silo, hosted this year’s event where PIR awarded a total of $180,000 in donations to organizations from the global .ORG Community across seven categories:

  • Community Building
  • Quality Education for All
  • Environmental Stewardship
  • Diversity, Equity, and Inclusion
  • Health and Healing
  • Hunger and Poverty
  • Rising Star (leaders under 30 making a difference in their communities)

In addition to the category winners, PIR named Democratic Republic of Congo-based nonprofit Fonds pour les Femmes Congolaises (The Fund for Congolese Women) the winner of the prestigious .ORG of the Year award, recognizing the organization’s work to empower women within the DRC by advancing initiatives to eliminate gender-based sexual violence, provide empowerment programs for women and girls, educate women about HIV/AIDS and reproductive health, and advocate for environmental justice and equitable access to resources and land.

The .ORG Impact Award judging panelists were inspired by how the organization’s work not only bridges the gap between international donors and local women’s initiatives but also creates the conditions for women to move from victims of violence to survivors, advocates, and leaders within their communities. As the 2025 .ORG of the Year, the Fund for Congolese Women will receive $50,000 in donations from Public Interest Registry.

“The winners of the .ORG Impact Awards are the very best of the .ORG Community and work tirelessly to create positive change every day. Public Interest Registry is thrilled to uplift their efforts and humbled by the work they are doing to build a bright future for us all,” said Jon Nevett, President and CEO of Public Interest Registry. “The work that this year’s .ORG of the Year winner, The Fund for Congolese Women, does to drive change from the ground up and uplift women in their communities deeply inspires me. I’m honored to celebrate them and shine a global spotlight on their extraordinary impact.”

In the seven years since the .ORG Impact Awards first started, Public Interest Registry has cumulatively donated $865,000 to .ORGs across the world. This year is a continuation of PIR’s ongoing commitment to uplift the changemakers making the world a better place.

“It’s an honor to join Public Interest Registry in celebrating this year’s .ORG Impact Award winners. These organizations are proof that passion and purpose can change lives and communities around the world. Their stories remind us that when we care and do for each other the world is naturally better,said Common.

“Community-building is at the heart of our mission at Fonds pour les Femmes Congolaises. Our organization started when a group of women came together and decided to fight for a better future for women and girls in the Democratic Republic of Congo,” said Gisele Kambesa, Program Assistant & Office Manager at Fonds pour les Femmes Congolaises (The Fund for Congolese Women). “We hope to use the award money to invest in even more women-led organizations who are making a positive impact on their communities. This award is not just for Congolese women, but all women that impact the world.”

2025 .ORG Impact Award Winners

.ORG of the Year – Fonds pour les Femmes Congolaises (The Fund for Congolese Women)

Donation Amount: $50,000 USD

Fonds pour les Femmes Congolaises is a nonprofit based in the Democratic Republic of Congo that funds and strengthens grassroots women’s organizations to advance peace, justice, and gender equality from the ground up. The organization empowers women through initiatives that combat gender-based violence, provide education on HIV/AIDS and reproductive health, and champion environmental justice. By bridging the gap between international donors and local women-led efforts, the Fund ensures resources reach communities that need them most.

Community Building – Fonds pour les Femmes Congolaises (The Fund for Congolese Women)

In addition to being named the .ORG of the Year, Fonds pour les Femmes Congolaises (The Fund for Congolese Women) is also the winner in the Community Building category.

Quality Education for All – IncluEdu

Donation Amount: $10,000 USD

IncluEdu is transforming education across Latin America by harnessing AI to teach sign language and advance deaf inclusion. Their platform equips educators with inclusive tools, provides real-time feedback, and creates accessible learning environments for students. By breaking down communication barriers, IncluEdu is helping build more inclusive schools, workplaces, and communities.

Environmental Stewardship – Nature Environment and Wildlife Society (NEWS)

Donation Amount: $10,000 USD

The Nature Environment and Wildlife Society (NEWS) is advancing biodiversity and climate resilience across India by restoring mangrove ecosystems. Working hand in hand with local communities, NEWS empowers women climate leaders and promotes sustainable livelihoods that protect natural resources. Its efforts ensure that both people and ecosystems can thrive together.

Diversity, Equity, and Inclusion – Humanos 3D

Donation Amount: $10,000 USD

Humanos 3D harnesses the power of emerging technologies to create personalized assistive devices for people with upper limb disabilities. Through 3D printing and community-driven innovation, the organization promotes inclusion, education, and independence. Their work transforms the lives of disabled individuals while fostering greater awareness and acceptance of disability inclusion.

Health and Healing – Access to Specialist Knowledge

Donation Amount: $10,000 USD

Access to Specialist Knowledge connects healthcare workers in underserved regions with U.S. board-certified specialists who provide pro bono consultations. This exchange of expertise empowers local providers, expands treatment options, and ensures patients in remote or resource-limited areas have access to high-quality care. The initiative is closing the global healthcare equity gap.

Hunger and Poverty – Andando

Donation Amount: $10,000 USD

Andando supports rural communities in Senegal through long-term partnerships that break the cycle of poverty. Their holistic approach strengthens access to clean water, healthcare, education, agroforestry, and microfinance programs. By focusing on the growth of entire villages, Andando creates pathways to financial independence and sustainable development.

Rising Star – Jovia Kisaakye, Ecobed Biotech

Donation Amount: $10,000 USD

Ecobed Biotech, founded and led by youth changemaker Jovia Kisaakye in East Africa, transforms food waste into mosquito-repellent lotion, clean fuel, and organic farm inputs. By addressing waste management, health, and agricultural needs simultaneously, Ecobed is advancing climate resilience, improving livelihoods, and protecting communities from disease. Their innovative approach demonstrates how young leaders are driving solutions with global impact.

About Public Interest Registry
Public Interest Registry (PIR) is a nonprofit that operates the .ORG top-level domain—one of the world’s largest generic top-level domains with more than 11 million domain names registered worldwide. .ORG is open to everyone, providing a global platform for organizations, associations, clubs, businesses and individuals to bring their ideas to life. PIR has been a champion for a free and open Internet for two decades with a clear mission to be an exemplary domain name registry, provide a trusted digital identity and help educate those who dedicate themselves to improving our world. PIR was founded by the Internet Society (internetsociety.org) in 2002 and is based in Reston, Virginia, USA. Visit www.pir.org for more information.

Media contact: pir@berlinrosen.com

 

Alpha Fusion and Kobe City Medical Center General Hospital Establish At-211 Investigational Drug Supply System

〜Driving Technology Transfer and Test Manufacturing Following Regulatory Approval to Launch Company-Led af-001 Trial〜

TOKYO, Oct. 8, 2025 /PRNewswire/ — Alpha Fusion Inc. (Alpha Fusion) is proud to announce a joint initiative with the Kobe City Medical Center General Hospital (KCGH) to establish a domestic supply system for investigational drugs utilizing Astatine-211 (At-211). This collaboration significantly advances the foundational work for what is expected to be the world’s first company-sponsored clinical trial using At-211 (as of September 2025).

KCGH has secured usage approval for At-211 from Nuclear Regulation Authority. The hospital is now proceeding with technology transfer and test manufacturing of the investigational drug for Alpha Fusion’s lead pipeline, af-001 (targeting differentiated thyroid cancer), in preparation for clinical trial initiation. This pioneering effort is setting up a system to seamlessly translate At-211 drug discovery into clinical practice.

Pioneering the World’s First Company-Led At-211 Investigational Drug Supply Chain

At-211 is recognized as an exceptionally promising radionuclide for targeted alpha therapy due to its short half-life (approx. 7.2 hours) and simple decay properties. However, a stable supply system for the investigational drug has been a major global hurdle, resulting in all clinical trials to date being academia-led.

In a breakthrough, the partnership with KCGH has established the crucial supply chain necessary to conduct clinical trials in Japan. KCGH operates a radioactive investigational drug GMP manufacturing facility. The hospital’s extensive experience in manufacturing investigational drugs using short-lived radionuclides for PET (Positron Emission Tomography) will be adapted for At-211 formulations. Establishing this supply system represents a landmark achievement for global therapeutic development using At-211.

Alpha Fusion has already formed a network with Japanese academic cyclotron facilities capable of At-211 production. By incorporating the hospital’s GMP manufacturing facility into the system, Alpha Fusion is building the world’s first multi-site supply chain for an At-211 radiopharmaceutical, connecting radionuclide production, drug manufacturing, and clinical trial sites.

af-001: The Lead Pipeline Harnessing At-211’s Unique Properties

At-211 supply chain development in Japan
At-211 supply chain development in Japan

Utilizing the collaborative framework with KCGH, Alpha Fusion is preparing to launch its first company-led trial with its lead pipeline, af-001. This program targets differentiated thyroid cancer. It exploits At-211’s unique property—shared with iodine—of being taken up by the Sodium-Iodide Symporter (NIS), allowing the drug to selectively accumulate in cancer cells. This specific approach is only feasible with At-211 among alpha-emitting radionuclides. Furthermore, the low surrounding radiation risk associated with At-211 is expected to allow for outpatient treatment, offering a powerful and highly convenient new therapeutic option for thyroid cancer patients.

This advancement solidifies the company’s leading global position as a “clinical-stage At-211 drug discovery company”.

Comment from Sunao Fujioka, CEO of Alpha Fusion:

“Targeted alpha therapy with At-211 could become a new cornerstone of cancer treatment, yet supply has been the global bottleneck. By partnering with KCGH to launch this investigational drug supply system, we have solved this key challenge ahead of the world, marking a giant leap toward clinical implementation. We are accelerating both our clinical development and supply efforts to deliver this new treatment to patients as quickly as possible.”

Comment from Tomohiko Yamane, Director of Department of Molecular Imaging Research, KCGH:

KCGH has, over the past decade, manufactured in-house investigational PET diagnostic radiopharmaceuticals, supporting numerous clinical trials, including those for Alzheimer’s disease treatments. In recent years, the use of radiopharmaceuticals has expanded from diagnostics to cancer treatment. We regard our participation in Alpha Fusion’s company-led trial as a significant step forward in applying our manufacturing and quality-control expertise in radiopharmaceuticals to therapeutic applications. From Kobe, we are committed to delivering new treatment options to patients in our community and around the world as swift as possible.”

Future Outlook

The valuable expertise gained by Alpha Fusion in technology transfer, investigational drug manufacturing, and logistics for At-211 therapeutics can be applied to future overseas clinical trials and commercial supply chain design. The successful system established in Japan will serve as a model case for replication and expansion in international markets, starting with the U.S. We are already in active discussions with domestic and international partners to manage these future supply chains.

At-211 supply chain development in US
At-211 supply chain development in US

Alpha Fusion plans to launch the clinical development of multiple At-211 pipelines both domestically and internationally, beginning with af-001. With the domestic investigational drug supply system now in place, we will accelerate the international rollout of At-211 drug discovery, aiming to create medicines for patients currently without treatment options.

Portland General Electric and GridCARE Accelerate Hundreds of Megawatts of Data Center Power in Leading U.S. Market

GridCARE’s AI-enabled grid planning approach accelerates time-to-power in Hillsboro, Oregon

REDWOOD CITY, Calif., Oct. 8, 2025 /PRNewswire/ — Portland General Electric (PGE) and GridCARE successfully completed their first joint project to accelerate large load interconnections using flexibility for data centers in Hillsboro, Oregon. This will result in over 80 MW of incremental capacity available for data center load in 2026, part of a total of more than 400 MW that will be energized by 2029. The novel generative AI-forecasting methodology more efficiently uses existing grid infrastructure to meet growing electricity demand in key economic sectors.

Hillsboro is a major data center hub in the U.S., thanks to its access to a diverse energy mix, robust fiber connectivity, and temperate climate. These advantages have attracted a large number of data center projects with billions of dollars to invest. Meeting this demand requires innovative approaches that both accelerate load interconnections and safeguard affordability for all customers.

“Delivering safe, reliable electricity at the lowest possible cost are our core customer commitments,” said Larry Bekkedahl, SVP of Strategy and Advanced Energy Delivery, Portland General Electric. “By working with GridCARE, we’ve successfully implemented an AI-based approach that helps us serve fast-growing data center demand while keeping costs low and maintaining system reliability. This kind of beneficial electrification is a win for our customers, our communities, and Oregon’s economy.”

A Breakthrough Approach

To identify and validate capacity on the existing system, PGE used GridCARE’s patented DeFlex™ methodology, to apply generative AI forecasting, detailed hourly demand modeling, and grid flexibility solutions. By optimizing the use of flexible resources such as batteries and onsite generation, PGE is able to interconnect multiple data center customers years earlier than initially expected.

This breakthrough approach provides multiple benefits:

  • Faster interconnection for large loads without waiting for multi-year upgrades,
  • More efficient use of existing grid assets, controlling costs for all customers, and
  • Increased flexibility that supports both system reliability and energy goals.

“The pace of AI and cloud growth demands new thinking about how we power the digital economy,” said Christian Belady, retired VP of Datacenter Advanced Development at Microsoft. “What PGE and GridCARE have accomplished in Hillsboro is the kind of innovation that not only enables AI and cloud expansion — it unlocks billions in new investment and accelerates returns across the entire North American ecosystem.”

Broader Impact

Nationally, electricity demand from data centers is projected to reach 6.7% to 12% of U.S. consumption by 2028, according to Lawrence Berkeley National Lab1. Utilities everywhere are grappling with how to deliver new capacity quickly while managing system costs and maintaining fair cost allocation for growth demand across customer classes.

GridCARE’s platform helps utilities validate their planning, model flexibility at scale, and relieve interconnection queues. By doing so, it supports billions in new local and regional economic investment while reinforcing the utility’s core mission of reliable and safe power delivery, while serving energy at the lowest cost possible.

This partnership strengthens Oregon’s role as a national technology hub and also positions Portland General Electric as one of the first utilities to utilize AI for large-scale load forecasting to benefit the grid and customers. 

“Utilities face a once-in-a-generation opportunity to meet exponential load growth,” said Amit Narayan, CEO of GridCARE. “By combining generative AI with grid flexibility, we help utilities like PGE move at the pace the AI economy requires. This project shows what’s possible when utilities and innovators partner closely.”

About GridCARE
GridCARE solves data center developers’ most urgent bottleneck — immediate access to power — through a pioneering physics-based generative AI platform that unlocks gigawatts of near-term capacity from today’s grid. Partnering with utilities, GridCARE applies a proprietary playbook to create additional network capacity on existing transmission infrastructure without costly upgrades or multi-year delays. Founded at Stanford’s Doerr School and backed by leading investors in Energy and AI, GridCARE is working with major technology and data center companies to accelerate interconnection requests for large-load and data center projects.

About Portland General Electric
Portland General Electric (NYSE: POR) is an integrated energy company that generates, transmits and distributes electricity to nearly 950,000 customers serving an area of 1.9 million Oregonians. Since 1889, Portland General Electric (PGE) has been powering social progress, delivering safe, affordable, reliable and increasingly clean electricity while working to transform energy systems to meet evolving customer needs. PGE customers have set the standard for prioritizing clean energy with the No. 1 voluntary renewable energy program in the country. PGE was ranked the No. 1 utility in the 2024 Forrester U.S. Customer Experience Index and is committed to reducing emissions from its retail power supply by 80% by 2030 and 100% by 2040. In 2024, PGE employees, retirees and the PGE Foundation donated $5.5 million and volunteered nearly 23,000 hours to more than 480 nonprofit organizations. For more information visit www.PortlandGeneral.com/news

1 Shehabi, A.; Newkirk, A.; Smith, S.; Hubbard, A.; Lei, N.; Siddik, M., et al. (2024). 2024 United States Data Center Energy Usage Report. Lawrence Berkeley National Laboratory. Report #: LBNL-2001637. http://dx.doi.org/10.71468/P1WC7Q Retrieved from https://escholarship.org/uc/item/32d6m0d1

Cisco Sets Benchmark with Industry’s Most Scalable, Efficient 51.2T Routing Systems for Distributed AI Workloads

Powered by the introduction of the new Silicon One P200 chip, Cisco’s groundbreaking 8223 routing systems redefine secure, efficient AI networking – enabling seamless ‘scale-across’ architectures that connect AI clusters across multiple data centers.

News Summary:

  • Cisco’s new AI networking systems redefine what’s possible with unprecedented scalability, power efficiency, and programmability built to directly address the critical challenges of connecting multiple data centers to securely run AI workloads.
  • The 8223 routing systems deliver industry-leading capacity and efficiency in a single ASIC router, and are now shipping to initial hyperscalers for secure, scalable AI infrastructure.
  • Cisco Silicon One is powering the next generation of AI networking with the new P200 chip, delivering deep-buffer routing silicon and enabling interconnect bandwidth scale of over 3 Exabits per second.

SAN JOSE, Calif., Oct. 8, 2025 /PRNewswire/ — Today, Cisco (NASDAQ: CSCO) unveiled the Cisco 8223, the industry’s most optimized routing system for efficiently and securely connecting data centers and powering the next generation of artificial intelligence (AI) workloads. As AI adoption accelerates, data centers face soaring demand, rising power constraints, and evolving security threats. The Cisco 8223 rises to the challenge as the only 51.2 terabits per second (Tbps) Ethernet fixed router built for the intense traffic of AI workloads between data centers.  Cisco today also announced its latest Silicon One innovation – the P200 chip – which sits at the core of the 8223. Together, these innovations empower organizations to shatter bottlenecks and future-proof their infrastructure for the AI era.

Cisco 8223 Routing Systems and the Cisco Silicon One P200
Cisco 8223 Routing Systems and the Cisco Silicon One P200

“AI compute is outgrowing the capacity of even the largest data center, driving the need for reliable, secure connection of data centers hundreds of miles apart,” said Martin Lund, EVP, Cisco’s Common Hardware Group. “With the Cisco 8223, powered by the new Cisco Silicon One P200, we’re delivering the massive bandwidth, scale and security needed for distributed data center architectures.”

In many of the world’s data centers, AI workloads are stretching power and space limitations. Hyperscalers can’t scale-up (add more capacity into each individual system) or scale-out (connect multiple systems within a data center) any further. This dynamic puts increasing demand on data center interconnects, as the industry must “scale-across” by distributing AI workloads across multiple data centers. Without addressing the connection points between data centers, organizations could face performance challenges, capacity bottlenecks and suboptimal processing that wastes time, power and money. The Cisco 8223 system gives organizations the flexibility and programmability necessary to build these networks, with deep buffering to provide the cross-site security and reliability necessary for crucial workloads.

Power Efficient. Scalable. Programmable. Secure.
Building a future-ready backbone AI network today is essential – one that can meet the power consumption challenges while remaining scalable, flexible and secure. The Cisco 8223 provides customers the capacity to handle surging workloads, the necessary flexibility with fully programmability, and the power efficiency to directly address power consumption challenges.

The 8223 is uniquely:

  • Power Efficient: The 8223 is the most power efficient routing system for scale-across networking. It is a deep-buffer routing solution optimized for fixed deployments that offers switch-like power efficiency, directly addressing the high energy demands of AI workloads. As a 3RU system, it is the most space efficient system of its kind. As AI clusters continue to ‘scale-across,’ power and space efficiency will only grow in importance.
  • Scalable without Compromise: The 8223 offers industry-leading bandwidth and the highest density of any fixed routing system in the industry. The only fixed routing system featuring 64 ports of 800G, the 8223 offers unmatched routing performance capable of processing over 20 billion packets per second and scaling up to 3 Exabits per second. It also features 800G coherent optics support, enabling data center interconnect and metro applications reaching up to 1000km. With the P200’s deep buffering capabilities, the new routing systems can absorb massive traffic surges from AI training, maintaining performance and preventing network slowdowns.
  • Intelligent and Adaptable: The 8223 can intelligently adapt to real-time network conditions. With the smart and programmable P200 silicon, it can support new, emerging network protocols and standards without requiring costly hardware upgrades. Networks can remain agile while preventing performance bottlenecks and accelerating the adoption of new features as AI traffic continues to evolve.
  • Secure: The 8223 offers protection at all levels – across hardware, software and entire networks. With features like line-rate encryption using post-quantum resilient algorithms, integrated security safeguards and continuous monitoring tools, the 8223 can safeguard against emerging threats. Seamless integration into Cisco’s observability platforms gives customers granular insights into network performance to help identify and resolve issues quickly, ensuring AI data traffic is secure and reliable.

Flexibility – An AI ‘Must Have’
The demands of AI networking aren’t simply growing, but are also constantly changing and evolving. Organizations demand infrastructure that is agile enough to change as business requirements do, and are seeking flexibility in deployment models so they can build networks for their exact needs. The Cisco 8223 will initially be available for open-source SONiC deployments, with IOS XR on the horizon.

In addition to its availability in the fixed 8223 system, the P200 silicon itself will be deployable in modular platforms and disaggregated chassis, offering customers architectural consistency for any size network. The Cisco Nexus portfolio will also support systems running NX-OS based on the P200 in the near future. Cisco is delivering the agility and operational flexibility required for today’s AI infrastructure.

Cisco Silicon One: The Industry’s Most Scalable and Programmable Unified Networking Architecture
Cisco Silicon One is a complete portfolio of networking devices across AI, hyperscaler, data center, enterprise and service provider use cases. Introduced in 2019, Cisco Silicon One is playing critical roles in major networks around the world.

Industry Reaction
“The increasing scale of the cloud and AI requires faster networks with more buffering to absorb bursts.  We’re pleased to see the P200 providing innovation and more options in this space.  Microsoft was an early adopter of Silicon One, and the common ASIC architecture has made it easier for us to expand from our initial use cases to multiple roles in DC, WAN, and AI/ML environments.” Dave Maltz, Technical Fellow and Corporate Vice President, Azure Networking, Microsoft

“As Alibaba continues to invest in and expand the cloud infrastructure, DCI is a critical pillar of our strategy. We are pleased to see the launch of Cisco Silicon One P200, the industry’s first 51.2T routing ASIC that delivers high bandwidth, lower power consumption, and full P4 programmability. This breakthrough chip aligns perfectly with the evolution of Alibaba’s eCore architecture. We plan to leverage the P200 to build a single chip platform, serving as a foundational building block for expanding our eCore deployment. Beyond supporting our Cisco Silicon One Q200 deployment scenarios, this new routing chip will enable us to extend into the Core network, replacing traditional chassis-based routers with a cluster of P200-powered devices. This transition will significantly enhance the stability, reliability, and scalability of our DCI network while keeping the simplicity. In addition, we are developing and exploring innovative disaggregated architectures using Cisco G200 for our high-performance datacenter network. The introduction of this advanced routing chip marks a pivotal step forward, empowering Alibaba to accelerate innovation and drive infrastructure expansion in the AI era.” Dennis Cai, Vice President, Head of Network Infrastructure, Alibaba Cloud

“As a long-standing Cisco customer, Lumen is actively advancing our network infrastructure to support the AI-driven economy. Cisco’s 8000 Series, Cisco Silicon One and Cisco’s pluggable optic technology represent key innovations that align with our goals for scalable, efficient multi-cloud connectivity. As we look to the future, we are exploring how the new Cisco 8223 technology may fit into our plans to enhance network performance and roll out superior services to our customers.” Dave Ward, Chief Technology Officer and Product Officer, Lumen

“As AI workloads rapidly outpace the capabilities of traditional data centers, the industry faces new challenges in bandwidth, reliability, and scale. The migration of data centers to remote locations for power access makes ultra-reliable, high-bandwidth interconnects essential. Cisco’s 8223, powered by Silicon One P200, marks a significant step forward, delivering the industry’s first 51.2-terabit fixed Ethernet router purpose-built for secure, power efficient scale-across networking.” Patrick Moorhead, CEO and Chief Analyst for Moor Insights & Strategy

Additional Resources:

About Cisco
Cisco (NASDAQ: CSCO) is the worldwide technology leader that is revolutionizing the way organizations connect and protect in the AI era. For more than 40 years, Cisco has securely connected the world. With its industry leading AI-powered solutions and services, Cisco enables its customers, partners and communities to unlock innovation, enhance productivity and strengthen digital resilience. With purpose at its core, Cisco remains committed to creating a more connected and inclusive future for all. Discover more on The Newsroom and follow us on X at @Cisco.

Cisco and the Cisco logo are trademarks or registered trademarks of Cisco and/or its affiliates in the U.S. and other countries. A listing of Cisco’s trademarks can be found at http://www.cisco.com/go/trademarks. Third-party trademarks mentioned are the property of their respective owners. The use of the word ‘partner’ does not imply a partnership relationship between Cisco and any other company.

Disclaimer: Many of the products and features mentioned are still in development and will be made available as they are finalized, subject to ongoing evolution in development and innovation. The timeline for their release is subject to change.