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ThreatBook Peer-Recognized as a Strong Performer in the 2025 Gartner® Peer Insights™ Voice of the Customer for Network Detection and Response — for the Third Consecutive Year

Recognition we believe underscores global customer trust and proven product excellence for security teams evaluating NDR solutions

SINGAPORE, Nov. 13, 2025 /PRNewswire/ — ThreatBook, a global leader in threat intelligence-based cybersecurity solutions, today announced that for its Threat Detection Platform (TDP), it has been recognized as a Strong Performer in the 2025 Gartner Peer Insights™ Voice of the Customer for Network Detection and Response (NDR).


This marks the third consecutive year that ThreatBook has received this distinction, which we believe underscores consistent customer satisfaction, product innovation, and operational excellence.

According to Gartner: “‘Voice of the Customer’ is a document that synthesizes Gartner Peer Insights reviews into insights for buyers of technology and services. This aggregated peer perspective, along with the individual detailed reviews, is complementary to Gartner expert research and can play a key role in your buying process. Peers are verified reviewers of a technology product or service, who not only rate the offering, but also provide valuable feedback to consider before making a purchase decision.”

“We’re thrilled to be recognized again as a Strong Performer in the Gartner Peer Insights ‘Voice of the Customer’ for NDR,” said Mr. Feng XUE, Chief Executive Officer of ThreatBook. “Our mission is to empower security teams with visibility and precision, especially in the Asia-Pacific region where attacks are becoming more sophisticated and targeted. We believe, this recognition reflects our customers’ trust in ThreatBook TDP’s ability to deliver real detection accuracy and operational resilience.”

Recognition Driven by Real-World Customer Feedback

To be included in the report, vendors must meet stringent inclusion criteria and are positioned within four quadrants based on user interest, product experience, and overall satisfaction — covering areas such as product capabilities, support, and delivery.

According to the research: “in the network detection and response market, Gartner Peer Insights published 1,263 reviews and ratings during the consideration period,” with 11 vendors ultimately meeting the inclusion standards. ThreatBook is among the few vendors recognized as a Strong Performer for three consecutive years. ThreatBook was among the few vendors to meet the full inclusion criteria and achieved 100% of customers willing to recommend ThreatBook TDP, based on 43 overall verified reviews submitted as of Aug 2025.

Enterprise users from finance, manufacturing, energy, services, and retail sectors across Asia-Pacific, North America, the Middle East, and Europe contributed feedback that rated ThreatBook TDP highly in overall product experience, detection precision, and operational efficiency.

TDP: Industry Leading Intelligence-Driven Detection and Response

As the market leader in China’s threat intelligence sector (iResearch, 2024 China Threat Intelligence Industry Development Report), ThreatBook integrates high-fidelity threat intelligence into its detection and response solutions.

ThreatBook TDP is a full-traffic, intelligence-driven NDR platform designed to provide visibility, context, and actionability at scale.

Proven Across Industries and Regions

Today, ThreatBook TDP is deployed in thousands of leading enterprises across critical industries including finance, energy, power, internet, and smart manufacturing.

It has become a core detection and response system for enterprise and government SOCs, helping them achieve visibility, precision, and proactive defense in dynamic threat environments.


Full review:

https://www.gartner.com/reviews/market/network-detection-and-response/vendor/threatbook/product/threatbook-tdp-ndr/review/view/6146934

https://www.gartner.com/reviews/market/network-detection-and-response/vendor/threatbook/product/threatbook-tdp-ndr/review/view/6145510 

About ThreatBook

ThreatBook is a global cybersecurity company specializing in advanced threat intelligence, detection, and response. Founded in 2015, ThreatBook equips enterprises, governments, and service providers with the clarity and context needed to defend against evolving digital risks.

By combining artificial intelligence with deep threat intelligence, ThreatBook delivers real-time visibility, hyper-accurate detections, and early-warning insights against nation-state actors, cybercriminal groups, and emerging attack campaigns. With unique vantage points from across the Asia Pacific region and beyond, ThreatBook provides intelligence coverage that bridges Eastern and Western threat landscapes, offering an unmatched perspective for global defenders.

ThreatBook: Act with Intelligence that Matters. To learn more, visit www.threatbook.io or follow us on LinkedIn.

Mastercard and Thunes Bring Stablecoin Payouts to the Mainstream

Collaboration to enable payouts to stablecoin wallets, giving banks, payment providers, and end-users greater choice and flexibility

SINGAPORE, Nov. 13, 2025 /PRNewswire/ — Mastercard and Thunes, the Smart Superhighway to move money around the world, have teamed up to accelerate global money movement for banks, payment service providers and end-users by expanding stablecoin wallet payout capabilities. Through this strategic collaboration, announced at the Singapore Fintech Festival, Mastercard Move will facilitate near real-time payouts to stablecoin wallets via Thunes’ Direct Global Network, harnessing the speed, liquidity, and 24/7 availability of regulated stablecoins.

Mastercard Move already enables payouts to cards, bank accounts, and cash across its global network. Through this alliance with Thunes, it will offer stablecoin wallets as a new endpoint – giving banks and payment providers greater flexibility in delivering funds, while offering end-users more choice in how they receive them.

Key benefits for banks, payment service providers, and end-users include:

  • Near Real-Time Payouts: Enable fast transfers to recipients’ stablecoin wallets, with 24/7 availability.
  • Expanded Choice: Allow banks and payment providers to offer payouts to stablecoin wallets alongside accounts, cards, and cash—unlocking new corridors and business models.
  • Financial Inclusion: Broaden payout options, mitigate currency volatility and reduce barriers to promote greater financial inclusion, particularly in underserved markets.

“As digital currencies become a bigger part of global money movement, this collaboration with Thunes reinforces our role as a trusted bridge between traditional and digital finance,” said Pratik Khowala, Global Head of Transfer Solutions at Mastercard. “With Mastercard Move, we already enable transfers in 150 currencies to over 10 billion endpoints—including accounts, cards, and cash. With this collaboration we’re adding stablecoin wallets to that mix. It’s all about giving end-users more choice and unlocking new possibilities for banks and payment service providers as digital currencies continue to grow.”

“Collaborating with Mastercard Move to enable stablecoin payouts is another step forward in our mission to enable the next billion end users to take part in the global economy,” said Chloe Mayenobe, President and Chief Operating Officer at Thunes. “By adding Thunes’ trusted Direct Global Network and Pay-to-Stablecoin-Wallets solution to their network and money movement capabilities, Mastercard is delivering faster and more inclusive payment options for individuals and businesses worldwide.”

This collaboration marks a key milestone in Mastercard Move’s commitment to facilitating stablecoin flows for financial institutions and wallets worldwide. It is also a powerful validation of the rapidly accelerating adoption of stablecoin payments for real-world utility. Thunes’ recently launched Pay-to-Stablecoin-Wallets solution, which will be integrated into Mastercard Move’s network, directly addresses the rapidly growing demand from individuals and businesses worldwide to receive instant, 24/7 payouts in a stable digital currency. 

Mastercard Move provides direct disbursers, banks, non-bank financial institutions, and their customers with fast, secure money movement solutions, both domestically and internationally. The portfolio reaches more than 200 markets and 150+ currencies, with access to over 95% of the world’s banked population.

About Mastercard

Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re building a resilient economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.

www.mastercard.com

About Thunes:

Thunes is the Smart Superhighway to move money around the world. Thunes’ proprietary Direct Global Network allows Members to make payments in real-time in over 130 countries and more than 80 currencies. Thunes’ Network connects directly to over 7 billion mobile wallets, stablecoin wallets and bank accounts worldwide, as well as 15 billion cards via more than 320 different payment methods, such as GCash, M-Pesa, Airtel, MTN, Orange, JazzCash, Easypaisa, AliPay, WeChat Pay HK and many more. Thunes’ Direct Global Network differentiates itself through its worldwide reach, in-house SmartX Treasury System and Fortress Compliance Platform, ensuring Members of the Network receive unrivaled speed, control, visibility, protection, and cost efficiencies when making real-time payments, globally. Members of Thunes’ Direct Global Network include gig economy giants like Uber and Deliveroo, super-apps like Grab and WeChat, MTOs, fintechs, PSPs and banks. Headquartered in Singapore, Thunes has offices in 14 locations, including Atlanta, Barcelona, Beijing, Dubai, Hong Kong, Johannesburg, London, Manila, Nairobi, Paris, Riyadh, San Francisco and Shanghai. For more information, visit: https://www.thunes.com/

Thunes to Power Real-Time Mobile Wallet Payouts for Mashreq Customers

Leveraging Thunes’ trusted Direct Global Network, the collaboration will deliver secure, real-time cross-border payments for millions of Mashreq customers.

SINGAPORE and DUBAI, UAE, Nov. 13, 2025 /PRNewswire/ — Thunes, the Smart Superhighway to move money around the world, announces a powerful new collaboration with Mashreq, a leading financial institution in the MENA region, to launch real-time mobile wallet payouts for millions of Mashreq customers.

Thunes to Power Real-Time Mobile Wallet Payouts for Mashreq Customers
Thunes to Power Real-Time Mobile Wallet Payouts for Mashreq Customers

Powered by Thunes’ trusted Direct Global Network, the partnership will enable Mashreq to connect directly to mobile wallets across Asia, Africa, and Europe and deliver faster, more affordable international transfers across key growth markets.

As Mashreq continues to expand across the Middle East and North Africa, this alliance marks a major step in transforming cross-border payments. Initially covering the bank’s top 30 payment corridors, the service will extend to additional countries over time. Together, Thunes and Mashreq are advancing digital banking innovation and making global money movement more seamless and inclusive.

As the world’s second-largest remittance hub, the UAE is expected to process USD 47 billion in outward flows in 2025, a figure which is set to grow by 4.7% annually. By joining forces with Thunes, Mashreq is supporting this growth and paving the way for fast, transparent, and efficient cross-border payments.

Kartik Taneja , Head of Payments & Consumer Lending at Mashreq, said: “By expanding our reach to mobile wallets through Thunes’ trusted Direct Global Network, we’re empowering millions of people to send funds to around 45 new destinations instantly and more affordably than ever before. With mobile wallet users projected to exceed five billion globally in the next few years, this capability is critical to serving our customers in key growth markets and driving greater financial connectivity. We are redefining what’s possible in international payments, and Mashreq is proud to be leading this transformation.”

Simon Nelson , Chief Commercial Officer at Thunes, added: “We are delighted to welcome Mashreq as a Member of our Direct Global Network. This alliance further strengthens our position in the Middle East, amplifying our mission to enable more consumers to take part in the global economy through instant, borderless payments. Trusted by leading banks and financial institutions worldwide, Thunes provides the secure and reliable Network needed to move money with confidence. Together with Mashreq, we’re enabling a new wave of payment innovation and connectivity that will reshape how money moves worldwide.”

ENDS

Contact:

WE Communications, thunes@wecommunications.com 

Anna Birdsall-Strong, Director of Brand and Public Relations, anna.birdsall@thunes.com 

 

Entrepreneur Universe Bright Group Reports Third Quarter 2025 Financial Results

XI’AN, China, Nov. 13, 2025 /PRNewswire/ — Entrepreneur Universe Bright Group (“EUBG” or the “Company”), a Nevada corporation, today announced its unaudited financial results for the quarter ended September 30, 2025.

Financial Highlights

  • Revenue: USD 1,217,966 for the three months ended September 30, 2025, compared to USD 1,670,203 for the three months ended September 30, 2024, representing a 27% decrease.
  • Gross Profit: USD 1,080,656 for the three months ended September 30, 2025, compared to USD 1,490,851 for the three months ended September 30, 2024, a decrease of 28%.
  • Net Income: USD 395,113 for the three months ended September 30, 2025, compared to USD 703,615 for the three months ended September 30, 2024, representing a 44% decrease.
  • Total Comprehensive Income: USD 477,097 for the three months ended September 30, 2025, compared to USD 872,508 for the three months ended September 30, 2024, representing a 45% decrease.
  • Cash Position: Cash and cash equivalents were approximately USD 9.56 million as of September 30, 2025.
  • Total Assets: USD 10.29 million as of September 30, 2025, compared with USD 9.39 million as of December 31, 2024.

Business Overview
EUBG provides digital marketing consultancy services through its wholly-owned PRC subsidiary, Xi’an Yunchuang Space Information Technology Co., Ltd., and its Hong Kong subsidiary. The Company helps startups and small businesses enhance brand visibility and improve sales through online platforms. EUBG does not use any VIE structure, and all operations are conducted through directly held subsidiaries in Hong Kong SAR and Mainland China.

Strategic Outlook
EUBG remains focused on expanding high-value digital advisory and data-driven marketing solutions to better serve clients in China’s rapidly evolving digital economy. The Company aims to strengthen service offerings in brand consulting, omni-channel e-commerce integration, and performance-based marketing campaigns. In addition, EUBG remains committed to maintaining robust cash flow discipline and full compliance with both PRC and U.S. regulatory frameworks.

Management Commentary
Mr. Guolin Tao, CEO of EUBG, stated:

“During the third quarter, we continued to operate prudently under a dynamic market environment. While revenues reflected temporary softness in client budgets, our underlying cash generation and balance sheet remained strong. We will continue to uphold compliance discipline, maintain financial flexibility, and deliver long-term value to our shareholders.”

About Entrepreneur Universe Bright Group
Entrepreneur Universe Bright Group is a Nevada-based holding company that conducts its operations through its wholly-owned subsidiaries in Hong Kong SAR and Mainland China. The Company primarily engages in consulting, sourcing, and digital marketing services to support business clients across multiple industries. For more information, please visit: www.eubggroup.com.

Safe Harbor Statement
This press release contains projections and “forward-looking statements” as defined by the Private Securities Litigation Reform Act of 1995 related to the Company’s business. Forward-looking statements include statements concerning plans, objectives, goals, strategies, future events or performance, and underlying assumptions and other statements that are not historical facts. When the Company uses words such as “may,” “will,” “intend,” “should,” “believe,” “expect,” “anticipate,” “project,” “estimate,” or similar expressions that do not relate solely to historical matters, it is making forward-looking statements.

Forward-looking statements are not guarantees of future performance and involve risks and uncertainties that may cause actual results to differ materially from those discussed in the forward-looking statements. These statements are subject to uncertainties and risks including, but not limited to: the Company’s goals and strategies; future business development; financial condition and results of operations; product and service demand and acceptance; competition and pricing pressures; changes in technology; government regulations; fluctuations in economic and business conditions in China; and assumptions underlying or related to any of the foregoing and other risks contained in the Company’s filings with the SEC. Investors are cautioned not to place undue reliance on any forward-looking statements in this press release. Additional factors are discussed in the Company’s filings with the SEC, available at www.sec.gov. The Company undertakes no obligation to publicly revise these forward-looking statements to reflect subsequent events or circumstances.

 

GAR Continues Record-Breaking Financial Results Run With Nine-Month Revenue High

  • Company builds on first half performance to reach record nine-month revenue of US$9.53 billion, up 21% year-on-year
  • Higher plantation output helped the Company capitalise on CPO price increase
  • EBITDA for the first nine months of 2025 rose by 16% to US$882 million, with recovery in downstream merchandising volume complementing upstream performance.

SINGAPORE, Nov. 13, 2025 /PRNewswire/ — Golden Agri-Resources Ltd (“GAR” or the “Company”) continued its run of record-high revenue for a second consecutive quarter, recording US$9.53 billion for the nine-month period of 2025. Higher plantation output helped the Company capitalise on a 17% rise in crude palm oil (“CPO”) prices (FOB Belawan), while a modest increase in downstream volume further supported revenue growth.

GAR recorded record-high revenue for the first nine months of 2025; continuing its first-half record revenue trend.
GAR recorded record-high revenue for the first nine months of 2025; continuing its first-half record revenue trend.

Nine-month EBITDA grew by 16% to reach US$882 million, preserving a healthy margin of 9.3%. Foreign exchange loss increased from US$2 million in the same period last year to US$15 million. Net profit remained strong, growing by 29% to reach US$284 million.

GAR’s balance sheet has also been strengthened, with an improved gearing ratio of 0.56 times and a much lower net debt to EBITDA ratio of 0.10 times.

On the outlook, Mr. Franky O. Widjaja, GAR Chairman and Chief Executive Officer commented: “Vegetable oil industry fundamentals remain robust, driven by steady and rising global demand. Limitations in supply growth capability, often compounded by unfavourable weather conditions, present ongoing challenges to meeting this demand. For palm oil, short- and medium-term supply growth has been constrained by ageing plantations and replanting activity which provide support to CPO prices. The market is also paying close attention to any changes in biofuel blending mandates across the world. Any shifts in trade, energy, and sustainability policies, coupled with geopolitical tensions, will have significant ripple effects on market dynamics, causing price volatility.”

Operational Highlights

Upstream output grew by 6% year-on-year, with modest increase in downstream volume despite volatile global economic environment
Upstream output grew by 6% year-on-year, with modest increase in downstream volume despite volatile global economic environment

GAR has continued replanting its old estates as part of the Company’s long-term yield improvement initiative. As a result, GAR’s planted area as of 30 September 2025 declined slightly to around 531,000 hectares, of which 491,000 hectares were mature. Nucleus and plasma estates made up 414,000 and 117,000 hectares of this area, respectively.

Fruit yield for the nine months of 2025 rose by 6% year on year from 12.8 to 13.6 tonnes per hectare supported by favourable weather conditions. This translated into a total fruit output of 6.7 million tonnes, with a corresponding increase in palm product output of 6% to almost 2.0 million tonnes.

The Company’s downstream business continued to make progress amidst a volatile global economic environment. While competitive market conditions have constrained downstream performance, GAR’s merchandising volumes have continued to rise over the last two quarters, resulting in increased sales volume for the nine-month period.

The Company will continue to strengthen its competitive edge through value-added products tailored to customer demands for functionality, quality and sustainability; anticipating factors that may influence price trends and trade flows while continuing to deliver on its commitments to responsible production.

Investment in Sustainability

GAR continues to advance its sustainability ambitions under the Company’s Collective for Impact commitments. GAR has commissioned three new methane capture plants at its mills in 2025, targeting annual CO₂e reductions of 150,000 tonnes from its Scope 1 emissions.

The Company has surpassed 2025 targets for its flagship independent smallholder programme Sawit Terampil, reaching 11,000 farmers by the end of September 2025. The programme helps smallholders to improve productivity, meet regulatory requirements, and access sustainable markets through recognised sustainability certification schemes. Almost 300 participants were awarded Roundtable on Sustainable Palm Oil certification at the organisation’s recent Roundtable Conference, bringing the total number of smallholders certified to 800.

At the recent Asia Sustainability Reporting Awards, GAR’s commitment to transparency and quality reporting was recognised with the Platinum Award for Supply Chain Reporting and the Bronze Award for Environmental Impact Reporting. These recognitions reaffirm GAR’s dedication to transparent and credible sustainability disclosures aligned with leading reporting standards.

About Golden Agri-Resources Ltd (GAR)

GAR is a leading fully-integrated agribusiness company. In Indonesia, it manages an oil palm plantation area of approximately 531,000 hectares (including plasma smallholders) as of 30 September 2025. It has integrated operations focused on the technology-driven production and distribution of an extensive portfolio of palm-based products throughout its established international marketing network.

Founded in 1996, GAR was listed on the Singapore Exchange in 1999 and has a market capitalisation of US$2.9 billion as of 30 September 2025. Flambo International Limited, an investment company, is GAR’s largest shareholder, with a 50.56% stake. In addition, GAR’s subsidiary, PT SMART Tbk was listed on the Indonesia Stock Exchange in 1992.

As an integrated agribusiness, GAR delivers an efficient end-to-end supply chain, from responsible production to global delivery. In Indonesia, its primary activities include cultivating and harvesting oil palm trees; the processing of fresh fruit bunch into crude palm oil (CPO) and palm kernel; refining CPO into value-added products such as cooking oil, margarine, shortening, biodiesel and oleo-chemicals; as well as merchandising palm products globally.

GAR’s products are delivered to a diversified customer base in over 110 countries through its global distribution network with shipping and logistics capabilities, destination marketing, on-shore refining and ex-tank operations. GAR also has complementary businesses such as soybean-based products in China, sunflower-based products in India, and sugar businesses.

Agoda Unveils Trending Camping Destinations Among South Korean Travelers This Fall

SEOUL, South Korea, Nov. 13, 2025 /PRNewswire/ — With the number of domestic campers estimated to exceed 7 million according to the Korea Tourism Organization (KTO), digital travel platform Agoda unveiled a ranking of the five most popular domestic camping destinations among South Korean travelers this fall based on booking data, with Jeju taking the crown.

Based on domestic bookings made on Agoda for accommodation types including tents, holiday and caravan parks, and farm stays during the cool fall-weather months of September to November, Jeju, Jeonju, and Gangneung ranked in the top three destinations among South Korean travelers. Samcheok and Namhae followed, rounding out the top five domestic camping destinations.

One of Gangneung’s campsites was listed among the top 10 domestic camping spots in the “Must-Visit Camping Map” curated by the KTO and Kakao Mobility, highlighting the city’s appeal as a premier camping destination.

Meanwhile, Namhae is emerging as a trending campsite with the “2025 Treasure Island Namhae Romantic Camping Festa,” held from September to November. The event offers unique programs that foster a camping culture, which supports local communities and encourages travelers to revisit.

South Koreans are also seeking out camping-style accommodation experiences beyond borders. Bali and Lombok (Indonesia) topped the list of most popular international camping destinations among South Korean travelers according to booking data on Agoda, followed by Pienza (Italy), Phuket (Thailand), and Majorca (Spain). Notably, Lombok has attracted attention among South Korean travelers after being featured on the reality TV show “Youn’s Kitchen,” showcasing the crystal-clear beaches and lush forests, while Pienza drew campers following its appearance on the TV show “Europe Outside Your Tent.”

Jay Lee, Regional Director, North Asia at Agoda, said, “Camping has become a popular form of relaxation and everyday enjoyment, with diverse styles such as traditional outdoor camping and glamping gaining traction. Agoda enables travelers to explore a wide range of accommodations from tents to caravan and holiday parks, making it easier to plan a camping experience that best suits their preferences.”

Travelers looking for the perfect camping or outdoor stays can start their search on Agoda to select from over 6 million holiday properties, more than 130,000 flight routes, and over 300,000 activities, all easily combined in a single booking. Discover the best deals on Agoda’s mobile app and visit Agoda.com for more information.

EdHeroes Awards 2025 Honoring Education Changemakers in Singapore

SINGAPORE, Nov. 13, 2025 /PRNewswire/ — EdHeroes, a global network dedicated to improving education, hosted the EdHeroes Awards 2025 on November 5th, 2025 in Singapore, uniting influential leaders, educators, philanthropists, entrepreneurs, and non-profit organizations who are committed to shaping the future of learning and driving systemic reform across Southeast Asia and beyond.

Left to Right: Jason Ng (ALLiN Technologies), Alina Baimen (CEO and Co-founder of EdHeroes), HRH Mangkoenagoro X, and Farhannisa Nasution (Expansion Director of EdHeroes) during EdHeroes Awards 2025, Glass Dome, Singapore (5/11/2025).
Left to Right: Jason Ng (ALLiN Technologies), Alina Baimen (CEO and Co-founder of EdHeroes), HRH Mangkoenagoro X, and Farhannisa Nasution (Expansion Director of EdHeroes) during EdHeroes Awards 2025, Glass Dome, Singapore (5/11/2025).

The awarding ceremony was attended by His Royal Highness Mangkoenagoro X of Mangkunegaran Palace of Surakarta, Central Java, Indonesia. His Royal Highness, who is also a recipient of the Honorary Award for Contribution to Cultural Preservation and Education, highlighted the challenges emerging in education such as inequality, cultural loss, and the digital divide can be tackled with collaborative efforts. “As we say in Javanese Philosophy, “Urip iku urup”, meaning to live is to give light. Let us continue to give light through knowledge, through compassion, and through collaboration, so from heritage to horizon, we may guide the world toward a brighter, wiser, and more peaceful future,” he emphasized.

In collaboration with ALLiN Technologies, Preschool Market, IECCS, Brands For Good, and The Saturday Movement, the evening featured a forward-looking panel discussion with Katarina Ueltschi (Managing Director of BERNINA), Bruce Liew (Senior Director, Disability & Inclusion of AWWA), Grace Chew (Director of Creative and Community at PayPan and Glassdome), and Dr. Lillian Koh (Founder & Chair of the Fintech Academy).

List of EdHeroes Awards 2025 Nominations and their Winners:

Award Winners:

  • Environmental Education Visionary: Terra SG
  • Early Childhood Education Excellence: New Life Preschool
  • Support for Young Talents: EB Impact
  • Equity and Inclusion in Education: Movement for the Intellectually Disabled of Singapore (MINDS)
  • Parent and Family Engagement: Tzu-Chi Foundation Singapore
  • Lifelong Learning Initiative: NICE Global

Honorary Awards Recipients:

  • Technology and Innovation in Education: Saikr (赛氪)
  • Rural Areas Education: Saturday Movement 
  • STEM Education Innovator: Preschool Market
  • Contribution to Cultural Preservation and Education: His Royal Highness Mangkoenagoro X of Mangkunegaran Palace of Surakarta, Central Java, Indonesia

You can access the full stories and pictures from the EdHeroes Awards 2025 here.

Ascletis Announces Co-formulation of ASC36, Once-Monthly Next-Generation Amylin Receptor Agonist and ASC35, Once-Monthly Next-Generation GLP-1R/GIPR Dual Agonist for Clinical Development

–  Using Ascletis’ proprietary Ultra-Long-Acting Platform technology, co-formulation of ASC36, a once-monthly subcutaneously administered amylin receptor peptide agonist and ASC35, a once-monthly subcutaneously administered GLP-1R/GIPR dual peptide agonist, demonstrated a comparable pharmacokinetic (PK) profile to ASC36 and ASC35 dosed alone in head-to-head non-human primate studies.

–  ASC36 monotherapy demonstrated approximately 32% greater relative body weight reduction compared to eloralintide monotherapy in a head-to-head diet-induced obese (DIO) rat study, while ASC35 monotherapy demonstrated approximately 71% greater relative body weight reduction compared to tirzepatide monotherapy in a head-to-head DIO mouse study.

–  Co-formulation of ASC36 and ASC35 demonstrated approximately 51% greater relative body weight reduction compared to the co-formulation of eloralintide and tirzepatide in a head-to-head DIO rat study.

–  Co-formulation of ASC36 and ASC35 had excellent chemical and physical stability with no aggregation or precipitation caused by fibrillation at neutral pH.

–  Submission of an Investigational New Drug Application to the U.S. Food and Drug Administration for co-formulation of ASC36 and ASC35 is expected in the second quarter of 2026.

–  The Company will host a conference call in Mandarin at 10:00 a.m. China Standard Time on November 13, 2025. 

HONG KONG, Nov. 13, 2025 /PRNewswire/ — Ascletis Pharma Inc. (HKEX: 1672, “Ascletis”) announces the co-formulation of ASC36, a once-monthly next-generation amylin receptor agonist and ASC35, a once-monthly next-generation GLP-1R/GIPR dual agonist for clinical development. Ascletis expects to submit an Investigational New Drug Application (IND) to the U.S. Food and Drug Administration (FDA) for co-formulation of ASC36 and ASC35 for the treatment of obesity in the second quarter of 2026.

Both ASC36, a once-monthly next-generation amylin receptor agonist, and ASC35, a once-monthly next-generation GLP-1R/GIPR dual agonist, were discovered and developed in-house utilizing Ascletis’ Artificial Intelligence-Assisted Structure-Based Drug Discovery (AISBDD) and Ultra-Long-Acting Platform (ULAP) technologies. Ascletis has successfully co-formulated ASC36 and ASC35 in the proprietary ultra-long-acting formulation to enable once monthly subcutaneous (SQ) administration using its ULAP technology. Co-formulation of ASC36 and ASC35 had excellent chemical and physical stability with no aggregation or precipitation caused by fibrillation at neutral pH. Some of amylin receptor peptide agonists aggregate or precipitate at neutral pH, which leads to loss of potency, turbidity/particles, device clogging, and higher immunogenicity risk.

In head-to-head non-human primate (NHP) studies, co-formulation of ASC36 and ASC35 demonstrated a comparable pharmacokinetic profile to ASC36 and ASC35 dosed alone, supporting once-monthly SQ dosing.

ASC36 monotherapy demonstrated approximately 32% greater relative body weight reduction compared to eloralintide monotherapy in a head-to-head diet-induced obese (DIO) rat study. ASC35 monotherapy demonstrated approximately 71% greater relative body weight reduction compared to tirzepatide monotherapy in a head-to-head DIO mouse study (press release). The co-formulation of ASC36 and ASC35 demonstrated approximately 51% greater relative body weight reduction compared to the co-formulation of eloralintide and tirzepatide in a head-to-head DIO rat study (Table 1).

Table 1. ASC36 monotherapy and co-formulation of ASC36 and ASC35 demonstrated statistically and significantly more weight loss than eloralintide monotherapy and the co-formulation of eloralintide and tirzepatide in DIO rats after 7-day treatment

Group

Dosing

Total body weight change
from baseline

Greater relative weight
loss versus eloralintide
monotherapy or co-
formulation of eloralintide
and tirzepatide

Obese rats treated
with vehicle

Vehicle,

SQ, Q2D

-0.5 %

–

Obese rats treated
with ASC36
monotherapy

5 nmol/kg,

SQ, Q2D

-9.6%

(p =0.028 vs eloralintide
monotherapy)

32%

(vs eloralintide
monotherapy)

Obese rats treated
with eloralintide
monotherapy

5 nmol/kg,

SQ, Q2D

-7.3 %

–

Obese rats treated
with co-formulation
of ASC36 and
ASC35

5 nmol/kg
ASC36/8
nmol/kg ASC35,

SQ, Q2D

-14.5%

(p <0.0001 vs eloralintide
monotherapy; p <0.0001
vs co-formulation of
eloralintide and
tirzepatide)

99%

(vs eloralintide
monotherapy)

 

51%

(vs co-formulation of
eloralintide and
tirzepatide)

Obese rats treated
with co-formulation
of eloralintide and
tirzepatide

5 nmol/kg
eloralintide/8
nmol/kg
tirzepatide,

SQ, Q2D

-9.6 %

–

Note: DIO rats/obese rats: diet-induced obese rats; SQ: subcutaneous; Q2D: once every two days. 

“Based on these encouraging preclinical data, we believe the co-formulation of ASC36 and ASC35 has the potential to lead to greater weight loss reduction in people with obesity than single-agent therapies can achieve alone,” said Jinzi Jason Wu, Ph.D., Founder, Chairman and CEO of Ascletis, “The growing body of evidence reinforces our platform technologies’ ability to design, optimize and develop multiple once-monthly SQ ultra-long-acting peptides.”

Monotherapy and Co-formulation Therapies with ASC36

Ascletis is developing ASC36 as the cornerstone of its once-monthly therapies for the treatment of cardio-metabolic diseases including obesity. With the potential for better efficacy and improved tolerability to GLP-1 therapies, ASC36 is an ideal drug candidate to develop as a monotherapy and co-formulations with other long-acting agents such as ASC35 and potentially ASC47, an adipose-targeted thyroid hormone receptor beta (THRβ) agonist. 

Ascletis’ AISBDD and ULAP technologies enable the Company to design, optimize and develop multiple once-monthly SQ ultra-long-acting peptides, including ASC35 and ASC36. Based on the properties of peptides, the Company can design, through its proprietary ULAP technology, various slow-release constants (k) for peptides in SQ depots to precisely release injected peptides over desired dosing intervals to reduce peak-to-trough ratios and improve clinical outcomes.

Conference Call

Ascletis will host a conference call in Mandarin at 10:00 a.m. China Standard Time on November 13, 2025. A live webcast of the call will be available via Tencent Meeting/ VooV Meeting, with the Meeting ID: 573-120-481, or access links of:

Chinese Mainland: https://meeting.tencent.com/dm/uIyhG5Mtu3op; or

International: https://voovmeeting.com/dm/uIyhG5Mtu3op.

About Ascletis Pharma Inc.

Ascletis Pharma Inc. is a fully integrated biotechnology company focused on the development and commercialization of potential best-in-class and first-in-class therapeutics to treat metabolic diseases. Utilizing its proprietary Artificial Intelligence-Assisted Structure-Based Drug Discovery (AISBDD) and Ultra-Long-Acting Platform (ULAP) technologies, Ascletis has developed multiple drug candidates in-house, including both small molecules and peptides, such as its lead program, ASC30, a small molecule GLP-1R agonist designed to be administered once daily orally and once monthly to once quarterly subcutaneously as a treatment therapy and a maintenance therapy for chronic weight management; ASC36, a once-monthly subcutaneously administered amylin receptor peptide agonist and ASC35, a once-monthly subcutaneously administered GLP-1R/GIPR dual peptide agonist for chronic weight management. Ascletis is listed on the Hong Kong Stock Exchange (1672.HK).

For more information, please visit www.ascletis.com.

Contact:

Peter Vozzo
ICR Healthcare
443-231-0505 (U.S.)
Peter.vozzo@icrhealthcare.com 

Ascletis Pharma Inc. PR and IR teams
+86-181-0650-9129 (China)
pr@ascletis.com
ir@ascletis.com