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Lao PM Sonexay Thanks Thailand for Xaysomboun Cave Rescue Support

Sonexay Siphandone, Prime Minster of Laos.

Prime Minister of Laos, Sonexay Siphandone, sent a letter of gratitude to Thai Prime Minister Anutin Charnvirakul, expressing his appreciation for Thailand’s support in the search and rescue operation at a flooded cave in Xaysomboun Province.

In the letter, dated 7 June, Sonexay said that on behalf of the Government and the people of Laos, he wished to express sincere gratitude to the Government of Thailand for authorizing the Saithan Thailand Association, the Metta Tham Kalasin Rescue Unit, and the Sawang Sivilay Rescue Unit to assist in the rescue of seven Lao citizens trapped in a cave in Longchaeng District following heavy rainfall.

He noted that the Lao government highly valued the timely assistance and tireless efforts of the Thai rescue teams, who had worked alongside Lao units and international experts from 24 May onward. 

Sonexay added that five of the trapped individuals had been successfully rescued and that efforts to locate the remaining two missing persons were continuing. 

The letter was sent as Sonexay departed for an official visit to Vietnam, scheduled from 7 to 9 June.

Seven Villagers in Xaysomboun Cave

Flash floods trapped seven men inside the cave on 20 May. 

Rescue teams found five survivors on 27 May and spent days pumping out floodwater while delivering food, medicine, and essential supplies. They brought the first survivor out on 29 May and rescued the remaining four on 30 May, despite repeated setbacks caused by heavy rain.

On 6 June, rescue teams suspended operations inside the partially flooded cave after they detected signs of a possible collapse at the entrance, raising serious safety concerns. 

Despite more than 10 days of intensive searches, they have not located the two remaining villagers, who entered the cave separately.

Before leaving, rescuers placed food, drinking water, and emergency supplies at several points inside the cave in case the missing villagers were still alive.

Expanding its partnership with non-profits, EZVIZ upgrades its Green Initiative to make a true impact on harmony between humans and nature with a week-long advocacy campaign

HOOFDDORP, Netherlands, June 8, 2026 /PRNewswire/ — EZVIZ, a world-leading smart home brand, announced to enter a new chapter of its EZVIZ Green Initiative by expanding environmental protection with two multi-year projects. Under the theme “Clean. Conserve. Coexist.”, the brand is launching a green advocacy week across the World Environment Day and World Oceans Day to engage partners and users in larger joint actions. By combining calls for climate resilience and ocean protection, EZVIZ responds to environmental issues with a larger proposition of sustainable coexistence between humans and nature.

EZVIZ launches a Green Advocacy Week to kick off its upgraded joint project in the new collaborative year with Treedom and Plastic Bank.
EZVIZ launches a Green Advocacy Week to kick off its upgraded joint project in the new collaborative year with Treedom and Plastic Bank.

“In the new phase, EZVIZ Green eyes on ecological vitality that benefits both people and other creatures,” said Joanne Cao, EZVIZ Board Secretary and Director of the ESG Committee. Highlighting its year-long projects with Treedom, a world-leading tree planting platform, and Plastic Bank, a global pioneer in ocean protection, EZVIZ tries to involve local communities more deeply to balance environmental protection with economic value. This aligns with the United Nations’ appeal to repair the relationship between humans and the planet. By building a positive cycle where people can gain from a vital ecosystem, it helps shape sustainability that endures over time, fulfilling its role as the participant in the UNGC and contributing to the SDGs.

“Like humans, all creatures are stakeholders of this planet,” said Cao. “With our Green Initiative, we aim to help create healthy ecosystems where nature and people complement each other.”

The EZVIZ Green upgrade drives change from land to sea through partnerships with Treedom and Plastic Bank. With Treedom, EZVIZ supports local farmers in planting trees, integrating agriculture with forestry across 11 countries. Estimated to reduce more than 738.2 tons of CO₂ in the next decade at the current scale, the growing global forest is expected to exceed 6,000 trees by 2027, further improving food security and economic development. In the new collaborative year, forest cover will extend to more regions across Southeast Asia, South America, and Africa, focusing on vital ecological areas like Ecuador to offset climate change.

Through Plastic Bank, EZVIZ helps combat plastic pollution by engaging collectors worldwide to gather bottles for additional income. To date, it has enabled the recycling of 1,000,000 bottles, prevented 20,000 kg of plastic from polluting water, and empowered collectors from 29 communities with exchanged social benefits. This year, EZVIZ concentrates on Southeast Asia, home to one of the world’s longest coastal archipelagos, to implement more careful and systematic plastic recycling, creating leverage to boost marine biodiversity and economic stability.

As part of the Initiative, EZVIZ also synergizes external cooperation with internal practices to amplify its impact. It strives for green innovation and launched the 4G battery camera family this year, which minimizes energy consumption without compromising safety. Innovation is in high gear to enhance wild animal detection, offering greater protection for both users and wildlife in remote areas.

Sensing Meets Connectivity: Calterah Launches Ultra-Powerful mmWave Radar Chips for High-Performance ADAS and Leading-Edge UWB Radar Solutions

SHANGHAI, June 8, 2026 /PRNewswire/ — On June 5, 2026, Calterah, a global leader in mmWave radar chips, unveiled its latest high-performance radar SoCs for ADAS and groundbreaking UWB radar solutions at its annual product and technology showcase, Calterah Day.

The newly launched Kunlun-Pro and Andes-Pro radar SoCs are engineered to address the market needs and emerging regulatory requirements for high-performance ADAS radar. As Euro NCAP 2026 raises the bar for automotive active safety and China progresses its national L2 ADAS and AEB regulations (currently in draft), ADAS radar is increasingly expected to deliver all-condition, full-speed-range perception for all road users.

  • Kunlun-Pro is an automotive 5T4R mmWave radar SoC featuring a 10 times more powerful RSP 2.0, higher DMIPS CPU performance, larger memory, over 2.5 dB SNR boost, and 25% more virtual channels compared to existing 4T4R products on the market. In demanding test scenarios, Kunlun-Pro reliably tracks weak targets at significantly longer ranges than 4T4R solutions.
  • Andes-Pro features the world’s first 6T6R ADAS radar SoC, achieving a 200 m detection range for weak targets and outstanding angular resolution (1° in azimuth; 3° in elevation). As a cost-effective alternative to expensive 8T8R products, the chip can also be scaled into a cascaded 12T12R imaging radar system, delivering high performance at lower system cost.

Beyond mmWave radar chip innovations, Calterah further explores the UWB radar functionality and emerging applications. The company claims the world’s first implementation of IEEE 802.15.4ab Sensing in the Dubhe CAL1106AQ SoC and has released two groundbreaking solutions—a Child Presence Detection (CPD) development suite and a Parking Assist System (PAS) development suite. The two suites are both built on CAL1106AQ—the world’s first IEEE 802.15.4ab-compliant and FiRa 4.0-certified 2T4R UWB SoC. With a unique 2T4R architecture, a Radar Leakage Suppression (RLS) module, and the IEEE 802.15.4ab Sensing feature, CAL1106AQ is capable of accurate height measurement, detection of nearby stationary objects, and high-speed parking lot search—tasks extremely challenging for conventional UWB products.

As of Q1 2026, Calterah has shipped over 30 million mmWave chips cumulatively, powering vehicle models from more than 30 OEMs. Calterah Founder and CEO Dr. Jiashu CHEN noted: “Combining mmWave and UWB technologies creates a seamless, safe, and intelligent driving experience—from car locating, unlocking, and assisted driving, to automated parking, car locking, child presence detection (CPD), and intrusion alerts.”

Chula Researchers Transform Cocoa Waste into Premium Livestock Feed

BANGKOK, June 8, 2026 /PRNewswire/ — A researcher from Chulalongkorn University has developed an innovative “cocoa-based mineral supplement” that transforms low-grade cocoa and discarded cocoa husks into value-added livestock feed, helping farmers reduce costs, improve cattle health, and lower greenhouse gas emissions under a circular economy model.

Chula Researchers Transform Cocoa Waste into Premium Livestock Feed
Chula Researchers Transform Cocoa Waste into Premium Livestock Feed

The project was led by Asst. Prof. Dr. Tansiphorn Na Nan, Acting Assistant Dean for Research and Academic Services at the Faculty of Integrated Agriculture and Director of the Innovation Center for Research and Development of Sustainable Cocoa Thailand (ISTC) in Nan province. The innovation emerged in response to worsening climate conditions that have caused cocoa crop losses of up to 80–90%, leaving farmers with large quantities of unsellable cocoa waste. At the same time, livestock farmers have faced rising feed costs during prolonged drought.

The research team created two forms of supplement: a compressed “lick block” for small farms and a powdered supplement for larger feed-mixing systems. Both products can incorporate cocoa waste as up to 30% of the ingredient formulation, creating a practical way to reduce agricultural waste while generating additional income for cocoa farmers.

According to the research, compounds naturally found in cocoa—including flavonoids, polyphenols, theobromine, and tannins—provide significant health benefits for livestock. Theobromine was found to improve cattle well-being, reduce inflammation, and enhance feed-to-meat conversion efficiency. In dairy cattle, testing showed that the supplement reduced somatic cell counts associated with mastitis by more than 70% and increased milk fat content by up to 15%.

Results in beef cattle were equally striking. Farmers who previously sold ordinary beef cattle for 20,000–30,000 baht per animal reported improved meat quality after using the supplement, with some cattle reaching premium A3 and A4 grades valued at more than 100,000 baht. Researchers also found that tannins in cocoa help suppress methane-producing bacteria in the rumen, reducing greenhouse gas emissions by up to 44% while redirecting energy toward muscle and fat production, improving marbling and meat quality.

Beyond cattle farming, the research is being expanded into poultry, goats, and shrimp farming, reinforcing the project’s guiding principle that “every cocoa bean must have a purpose” and demonstrating how circular economy innovation can create sustainable value across multiple agricultural sectors.

For more information, contact the Faculty of Integrated Agriculture, Chulalongkorn University at Tel. +662 218 1243, or visit www.cusar.chula.ac.th.

Media Contact:  
Chula Communication Center
Email: Pataraporn.r@chula.ac.th

Technology Empowers Buddhist Wisdom: NetDragon Websoft (Hong Kong) Debuts a Suite of Digital Buddhist Products at the 21st UN Vesak Day

BANGKOK, THAILAND – Media OutReach Newswire – 8 June 2026 – On May 29, the commemorative event for the 21st United Nations Vesak Day was grandly convened at the United Nations Conference Centre (UNCC) in Bangkok. NetDragon Websoft (Hong Kong) consistently applies state-of-the-art digital technologies to advance the digital transformation and global promotion of Buddhist culture. As the world’s sole tech company invited to showcase at the UN Vesak Day for ten straight years, it presented an array of digital products at this year’s event.

Debut of In-house Developed Products, Including Dharma AI-Agent and All-in-one Digital Terminals

At its Bangkok UNCC exhibition booth, NetDragon presented its full lineup of self-developed digital solutions, demonstrating real-world applications of large language models, multimodal interaction and artificial intelligence in Buddhist cultural promotion and digital meditation. Headlining the showcase was Dharma AI-Agent, an all-in-one intelligent tool platform unveiled to the public for the first time. Live demonstrations featured core practical capabilities including one-click AI generation of images, texts and videos, instant cross-platform social media distribution and traffic generation, intelligent pastoral care for devotees, and full-spectrum SaaS operation and maintenance for Buddhist monasteries.

The Most Ven. Phrabrahmapundit Visits the Booth and Commends Tech-driven Dharma Propagation

During the event, The Most Ven. Phrabrahmapundit paid a special visit to NetDragon’s exhibition stand to inspect Dharma AI-Agent in detail and spoke highly of the company’s innovative achievements in advancing Dharma dissemination through digital technology.

Mi Xiong, CEO of the Thailand National Digital Buddhism Innovation & Research Center and General Manager of NetDragon’s Digital Life Education Division, remarked in an interview: “Following Thailand’s 2023–2037 Buddhist development roadmap, we help its Supreme Sangha Council deliver national digital Buddhism plans and launched the country’s first official digital Buddhism center setting Theravada digital standards. Through UN Vesak, we’ll cooperate with global Buddhist groups, upgrade Dharma AI-Agent and AI meditation tools to ease scripture promotion and advance Buddhist modernization and globalization, boosting cross-cultural communication and global sustainability.”

The harmonious integration of technological advancement and Buddhist humanistic philosophy perfectly embodies this year’s conference theme: The Role of Buddhist Wisdom in Advancing Global Sustainable Development and Building a Shared Future for Mankind.

Virtual Tour of Wat Prayoon:https://www.thaidigitaltemple.com/digital/map/buddhism/newTemp/

Online Donations for Wat Prayoon:
https://www.thaidigitaltemple.com/digital/lamp/buddhism/newTemp
Hashtag: #DigitalBuddhism

The issuer is solely responsible for the content of this announcement.

Luxury Hair Clinic Sheer Reprime Marks 8th Anniversary with a Flagship Expansion into Hong Kong’s Prestigious Wellington Street

Luxury hair and scalp rejuvenation pioneer Sheer Reprime invests nearly HK$10 million to deploy next-generation, FDA and CE-certified hair restoration and scalp rejuvenation technologies.


HONG KONG SAR – Media OutReach Newswire – 8 June 2026 – Celebrating eight years of clinical excellence, premier hair and scalp rejuvenation brand Sheer Reprime today announced the grand opening of its ultra-luxury flagship center on Wellington Street, Central. Representing a strategic investment of nearly HKD10 million, the expansive facility positions Sheer Reprime at the epicenter of Hong Kong’s elite financial and cultural district. This expansion marks a new era of medical-grade, advanced hair restoration and scalp rejuvenation.

Hair and scalp rejuvenation pioneer Sheer Reprime expands into Hong Kong's Wellington Street with a flagship center.
Hair and scalp rejuvenation pioneer Sheer Reprime expands into Hong Kong’s Wellington Street with a flagship center.

Located at 50 Wellington Street, adjacent to the iconic Yung Kee restaurant, the near-full-floor flagship features private treatment suites engineered for maximum comfort and discretion. The venue is optimized for busy and successful individuals, stars and celebrities seeking world-class clinical trichology with exceptional hospitality.

Bridging Follicle Biology and Biophotonics

Sheer Reprime’s expansion directly addresses a surging global market demand for scientifically backed hair-loss solutions, particularly as stress and lifestyle factors accelerate the onset of premature thinning among younger demographics.

“Our expansion into the heart of Central marks a watershed moment for Sheer Reprime,” said a Brand Spokesperson. “The modern consumer demands rigorous, evidence-based hair and scalp treatments. Sheer Reprime is built at the intersection of Follicle Biology and Biophotonics. Our multi-million-dollar investment into an advanced clinical instrumentation allows us to optimize the scalp microenvironment at a cellular level, far surpassing the limitations of older generation treatments.”

Internal clinical metrics validate the brand’s scientific approach. In a recent study tracking 100 urban professionals over a 12-week regimen of Sheer Reprime’s laser hair rejuvenation therapy, participants demonstrated an average increase of 22% in hair shaft thickness and an 18% increase in active follicular density.

Departing from standard industry practices focused merely on surface-level scalp cleansing, Sheer Reprime introduces its proprietary Connotation Therapy. This multi-modality framework combines technologies which have received FDA, Medical CE, and EU MDR (Medical Device Regulation) certifications. Amongst them SLD LLLT hair loss treatment, which delivers biophotonic laser energy 3–5mm beneath the scalp surface to revive the follicular base. Winback Tecar Therapy and 500kHZ cellular radio frequency, which utilizes deep thermal energy to enhance localized microcirculation across the head, neck, and shoulders, maximizing nutrient and oxygen delivery to the hair bulb while flushing out metabolic waste and DHT (dihydrotestosterone).

The launch of Sheer Reprime’s Wellington Street flagship redefines the luxury trichology landscape in Hong Kong, merging clinically proven regenerative technologies with an unparalleled bespoke experience.

Hashtag: #sheerreprime #煥光活髮

The issuer is solely responsible for the content of this announcement.

About Sheer Reprime

Sheer Reprime is a premier scientific hair and scalp rejuvenation brand. By fusing Follicle Biology with Biophotonics, the brand transcends the boundaries of traditional hair care. Operating its multi-million-dollar flagship in Central, Sheer Reprime deploys FDA and CE-certified medical-grade technologies to lead the global industry into the era of cellular hair restoration. For more information, visit:

Trransfer Technologies And LINE GO Partner To Expand Enterprise Ground Transportation Across Taiwan And Global Markets

Partnership combines LINE GO’s MaaS ecosystem platform with Trransfer Technologies’ global B2B ground transportation platform to serve Taiwan’s growing outbound business travel demand


SINGAPORE – Media OutReach Newswire – 8 June 2026 – Trransfer Technologies, a global B2B ground transportation platform serving corporate travel managers, private aviation firms, banks, luxury concierge services and enterprise customers to fulfill across more than 80 destinations worldwide, announced the official launch of its strategic partnership with LINE GO, Taiwan’s premier MaaS (Mobility as a Service) ecosystem platform. Officially commencing today, the partnership follows a successful one-month operational pilot since May 11, 2026, and is designed to unlock new enterprise demand in Taiwan while creating a scalable outbound travel solution for Taiwanese companies, multinational corporations and business travelers.

Taiwan’s outbound travel market reached 18.94 million departures in 2025, a 12.43 percent increase from 2024 and a new historical high. This upward trajectory underscores a compelling opportunity for enterprise-focused mobility providers to capture demand from corporations and business travelers who require seamless, reliable ground transportation solutions across global destinations.

A Partnership Built on Complementary Strengths

Trransfer Technologies will bring international corporate and enterprise travel demand into Taiwan, with LINE GO providing local fulfillment through its established mobility network, operational capabilities and deep integration within the LINE ecosystem. LINE GO’s MaaS platform aggregates seven mobility services including taxi-hailing, car rentals, airport shuttles, designated driver services, scooter sharing, private car charters and an EV charging network, giving enterprise clients a comprehensive local mobility experience upon arrival in Taiwan.

Looking ahead, both companies will extend their collaboration to serve the outbound travel needs of Taiwan-based enterprises, leveraging Trransfer Technologies’ global destination network across more than 80 destinations worldwide. This positions both companies to become the preferred mobility partner for Taiwanese businesses and multinationals requiring end-to-end ground transportation coordination across borders.

Targeting Taiwan’s Enterprise Traveler Segment

The partnership specifically targets multinational corporations, corporate travel managers, enterprise clients and high-frequency business travelers. As Taiwan’s outbound travel continues its upward trajectory, enterprises increasingly need partners who understand both local logistics and the complexity of global coordination.

“This partnership creates immediate strategic value for both companies. LINE GO brings market-leading mobility technology and operational insights, while Trransfer Technologies contributes the global platform, enterprise workflows and international fulfillment network. Together, we are building a scalable outbound mobility solution for Taiwanese enterprises traveling globally.”

Michael Chiay, Chief Executive Officer, Trransfer Technologies

“This collaboration marks a transformative milestone in LINE GO’s journey. We are proud to offer our partners a one-stop solution that delivers on our promise to make every journey smarter, safer, and more efficient.”

Isaac Lin, Managing Director, LINE GO
Hashtag: #TrransferTechnologies #MaaS #BusinessTravel #CorporateTravel #TravelTech #GlobalMobility #TrransferTechnologies #LineGo #EnterpriseTravel #SmartMobility #concierge

The issuer is solely responsible for the content of this announcement.

About Trransfer Technologies

Trransfer Technologies is a global B2B ground transportation platform connecting corporate travel managers, private aviation firms, banks, luxury concierge services and enterprise customers with local ground transportation operators to fulfill across more than 80 destinations worldwide. The company provides a unified platform designed to simplify business travel mobility, improve supplier coordination and support seamless ground transportation fulfillment across markets.

For more information, please visit .

About LINE GO

LINE GO is Taiwan’s premier MaaS platform offering taxi-hailing, car rentals, airport shuttles, designated driver services, scooter sharing, private car charters and an EV charging network, all within the LINE ecosystem. In 2025, LINE GO achieved dual ISO 27001 and ISO 27701 certifications, underscoring its commitment to world-class information security and data privacy.

Head-to-head Study Validates the Clinical Advantage of New-generation Biased GLP-1: Ecnoglutide Delivers 35% Greater Weight Loss than Semaglutide

NEW ORLEANS, June 8, 2026 /PRNewswire/ — Hangzhou Sciwind Biosciences Co., Ltd. (“Sciwind Biosciences”), a commercial-stage biopharmaceutical company focused on discovering and developing innovative therapies for metabolic diseases, today announced that key data from a head-to-head study (SLIMMER-UP-SWITCH) evaluating ecnoglutide versus semaglutide was presented as a Late-Breaking abstract at the 86th Scientific Sessions of the American Diabetes Association (ADA) 2026. Interim analysis results showed that ecnoglutide, the world’s first approved cAMP-biased GLP-1 receptor agonist, demonstrated greater weight loss compared to semaglutide, with a 35% greater reduction in body weight, a 20% greater reduction in waist circumference at Week 20, and nearly twice as many patients achieving ≥10% body weight loss.

Professor Linong Ji, Director of the Department of Endocrinology at Peking University People’s Hospital, stated that this study provides the first direct clinical evidence validating the clinical advantages of the innovative cAMP-biased GLP-1 receptor agonist mechanism. By optimizing GLP-1 receptor signal transduction, it delivers superior clinical benefits over traditional GLP-1 receptor agonists, providing high-quality evidence-based medical evidence for the field of weight management.

Clear Weight Loss Advantage at Week 20: 35% Greater Mean Weight Reduction vs. Semaglutide, ≥10% Weight Loss Response Rate Nearly Twofold Higher

This study enrolled 163 adult patients with obesity (body mass index [BMI]≥30 kg/m²) across 17 research centers in China. Participants were randomized 1:1 to receive once-weekly subcutaneous injections of either ecnoglutide or semaglutide at the same maintenance dose of 2.4 mg¹.

Study data showed that at week 20, the least-squares mean percentage change in body weight from baseline was -12.8% in the ecnoglutide group and -9.5% in the semaglutide group (P<0.0001). The proportion of participants achieving ≥5% weight loss was 99% in the ecnoglutide group versus 86% in the semaglutide group (P<0.01). The proportion achieving ≥10% weight loss was 74% in the ecnoglutide group versus 40% in the semaglutide group (P<0.001).

Significant Circumference Benefits: 20% Greater Waist Circumference Reduction vs. Semaglutide

In addition to potent weight loss, ecnoglutide also demonstrated remarkable advantages in improving body circumference. Study data showed that at week 20, the mean reduction in waist circumference from baseline was 10.5 cm in the ecnoglutide group and 8.7 cm in the semaglutide group (P<0.05), representing a 20% greater reduction for ecnoglutide. Improvements in other circumference measures including arm circumference and neck circumference were also superior to those of semaglutide¹.

Professor Linong Ji noted: “Central obesity, characterized by abdominal fat accumulation, not only affects body shape but is also a key risk factor for type 2 diabetes, metabolic syndrome and cardiovascular diseases. While effectively reducing body weight, ecnoglutide significantly improves central obesity and local fat accumulation, optimizing body shape while lowering the risk of related metabolic diseases.”

Nobel Prize-Winning Research Translation: Biased Mechanism Achieves Balance Between Efficacy and Safety

Traditional GLP-1 receptor agonists mostly adopt a “full pathway activation” mode, which activates weight loss signaling pathways but also often activates pathways associated with gastrointestinal adverse events and receptor desensitization, making it difficult to balance potent weight loss and good tolerability.

Based on Nobel Prize-winning research findings3, ecnoglutide further contributes the industry-wide challenge of balancing efficacy and tolerability in traditional weight loss therapies by optimizing GLP-1 receptor signal transduction. Its safety profile was also reaffirmed in this head-to-head study. Consistent with previous SLIMMER study results, ecnoglutide demonstrated favorable gastrointestinal safety1,2.

Dr. Hai Pan, Founder and CEO of Sciwind Biosciences, stated: “We are honored to present this major breakthrough at the ADA Scientific Sessions, the world’s most influential academic conference in the global metabolic field. Better weight loss therapies do not come from simple stacking of targets, but from precise regulation of key biological mechanisms. The head-to-head study of ecnoglutide versus semaglutide provides direct clinical evidence for this innovative concept, marking an important milestone in the translation of biased agonist mechanisms from cutting-edge science to clinical application. From Nobel Prize-level basic research to patient-accessible clinical products, we will remain committed to scientific translation, turning more cutting-edge scientific achievements into tangible health benefits for patients worldwide.”

Jean-Christophe Pointeau, Global Senior Vice President and President of Pfizer China, stated: “These new findings add to the clinical evidence that new generation biased GLP-1 therapies in weight management and metabolic treatment can offer patients enhanced efficacy, tolerability and safety. As the commercialization partner for ecnoglutide in China, Pfizer is proud to support the introduction of this therapy and help expand access, providing new options to help people in China manage weight in a healthy way.”

About the SLIMMER-UP-SWITCH Head-to-Head Study¹

SLIMMER-UP-SWITCH is a multicenter, randomized, open-label Phase 2 clinical trial conducted at 17 research centers in China, enrolling 163 adult patients with obesity (BMI ≥30 kg/m²). Participants were randomized 1:1 to receive once-weekly subcutaneous injections of ecnoglutide or semaglutide for a 60-week treatment period, with a pre-specified interim analysis conducted at Week 20. The interim analysis data of this study has been selected as a Late Breaking abstract and presented as a poster at the 2026 ADA Scientific Sessions.

About the SLIMMER Study²

The SLIMMER study is a large-scale Phase 3 clinical trial that enrolled 664 Chinese adult subjects with overweight or obesity. In the SLIMMER study, ecnoglutide demonstrated clinically meaningful efficacy. After 48 weeks of treatment, subjects in the highest dose group (2.4 mg) achieved an average weight loss of 15.4%, with 92.8% of subjects losing more than 5% of their body weight. The study also observed a significant reduction in waist circumference (average reduction of 12.8 cm), a 53.1% average reduction in liver fat content in subjects with baseline fatty liver disease, and significant improvements in multiple metabolic indicators including blood pressure, blood lipids and blood glucose; in addition, uric acid levels decreased by an average of 54.3 μmol/L. In the study, the treatment discontinuation rate due to adverse events was 2%, and the discontinuation rate due to gastrointestinal adverse events was 0.6%.

About Ecnoglutide

Ecnoglutide is a cAMP-biased GLP-1 receptor agonist developed by Sciwind Biosciences for obesity and related metabolic diseases. Pfizer has exclusive commercialization rights for Sciwind’s injectible ecnoglutide product in Mainland China.

About Sciwind Biosciences

Sciwind Biosciences is a commercial-stage biopharmaceutical company, dedicated to addressing the unmet medical needs in the field of weight management and metabolic diseases. Sciwind has established a robust pipeline anchored by the lead asset, ecnoglutide (XW003). It has developed multiple proprietary technology platforms, including biased agonist discovery platform, long-acting and oral peptide delivery platforms, and has identified a series of drug candidates based on these core technology platforms. Sciwind has built an extensive pipeline targeting GLP-1 and synergistic pathways, offering both injectable and oral treatment solutions to deliver sustainable and high-quality therapies for patients with metabolic diseases.

For more information, please visit Sciwind Biosciences’ official website: www.sciwind.com.cn 

References

  1. 2026 ADA poster 12-B. Study number SCW0502-1122
  2. Ji L, et al. Lancet Diabetes Endocrinol. 2025 Sep;13(9):777-789
  3. Mullard A. Nat Rev Drug Discov. 2023 May;22(5)347-348.