HONG KONG, Aug. 19, 2025 /PRNewswire/ — The Digital Asset Anti-Money Laundering Council (DAAMC), a groundbreaking, industry-led nonprofit organization supported by the Hong Kong Virtual Assets Industry Association (HKVAIA), proudly announces its launch. DAAMC is dedicated to promoting compliant stablecoin issuance and enhancing financial integrity in Hong Kong’s digital asset ecosystem through collaboration among regulated financial institutions to develop and promote best-in-class Anti-Money Laundering and Counter-Financing of Terrorism (AML/CFT) standards and practices.

DAAMC responds to the Hong Kong Monetary Authority’s (HKMA) Guideline on Anti-Money Laundering and Counter-Financing of Terrorism (For Licensed Stablecoin Issuers) and explores emerging global industry compliance standards, such as on-chain identity verification, to ensure Hong Kong’s regulated stablecoins achieve mainstream adoption by balancing risk control with sustainable business development.

The Council, initiated by four leading organizations with diverse expertise, is committed to shaping the future of digital finance in Hong Kong, focusing on stablecoin innovation and compliance: 

• HashKey Group: A leading digital asset financial services group in Asia with global operations. Its subsidiary, HashKey Exchange, is the licensed virtual asset exchange in Hong Kong, holding Type 1, Type 7, and AMLO licenses issued by the Hong Kong Securities and Futures Commission.
• RD InnoTech Limited (a subsidiary of RD Technologies Group): A participant in the HKMA Stablecoin Issuer Sandbox, advancing compliant stablecoin issuance, ecosystem development, and use-case expansion. 
• Beosin: A leading blockchain security and compliance solutions company specializing in smart contract security audit, AML/CFT tools, and blockchain forensics.
• SlowMist: A leading blockchain threat intelligence firm, providing services such as security audits, red teaming, AML/CFT solutions, and more.

This diverse coalition reflects DAAMC’s commitment to uniting industry expertise to address the unique AML/CFT challenges of digital assets, including stablecoins, to achieve large-scale adoption and integration with traditional finance. By integrating expertise in digital asset trading, stablecoin innovation, blockchain analytics, and threat intelligence, DAAMC aims to establish a compliant ecosystem, setting a global benchmark for financial integrity in Hong Kong’s stablecoin issuance.

A Strategic Response to Hong Kong’s Stablecoin Ambitions

Hong Kong is solidifying its position as a global leader in digital finance through the government’s Digital Asset Policy Statement 2.0 (June 2025) and the recently effective Stablecoins Ordinance. DAAMC’s establishment aligns with this vision, directly supporting the HKMA’s Guideline on Anti-Money Laundering and Counter-Financing of Terrorism (For Licensed Stablecoin Issuers) to ensure regulated stablecoins comply with global financial standards while promoting innovation. DAAMC actively engages with industry discussions on regulatory strictness, committed to researching and exploring how to balance regulatory requirements with business development, enabling Hong Kong-issued compliant stablecoins to achieve mainstream adoption by regulated institutions and traditional enterprises.

Initiated by founding members HashKey Group, RD InnoTech Limited, Beosin, and SlowMist, DAAMC is dedicated to promoting digital asset industry development and collaboration, through activities such as offline seminars to engage relevant industry stakeholders in exploring innovative compliance solutions for stablecoins. DAAMC will soon release two AML technical reports on stablecoins to provide further industry guidance. At the end of this month, DAAMC will host a seminar, bringing together industry experts to discuss stablecoin compliance and innovation strategies. All industry stakeholders are cordially invited to participate.

DAAMC’s Mission and Impact

DAAMC serves as a central platform for regulated financial institutions—including banks, licensed Virtual Asset Service Providers (VASPs), and future licensed stablecoin issuers—to collaborate on critical initiatives. Led by its founding members, the Council will focus on: 

• Developing Industry Best Practices: Creating practical guidelines for on-chain identity verification, Travel Rule implementation, risk-based digital asset management, and AML frameworks for Decentralized Finance (DeFi) to ensure compliance aligns with traditional financial standards. 
• Fostering Regulatory Dialogue: Building trusted communication channels with regulators and law enforcement to shape effective policies that support stablecoin mainstreaming. 
• Promoting Professional Education: Partnering with academic institutions to elevate AML/CFT expertise tailored to stablecoin issuance and digital asset compliance. 
• Encouraging Responsible Innovation: Balancing risk control with sustainable business development, ensuring regulated stablecoins thrive in Hong Kong’s compliant ecosystem.

DAAMC welcomes participation from a wide range of stakeholders, including Institutional Members (banks, VASPs, stablecoin issuers), Associate Members (audit firms, legal firms, professional bodies such as ACAMS and HKIB), and Educational Partners. By joining DAAMC, organizations will shape policy, manage risks, and demonstrate a commitment to financial integrity while promoting the mainstream adoption of regulated stablecoins.

A Call to Action

With Hong Kong’s Stablecoins Ordinance taking effect in August 2025, DAAMC’s launch underscores its commitment to driving digital asset industry compliance and integrity through collaborative leadership. DAAMC invites leading industry companies, compliance institutions, and innovative enterprises to join this transformative initiative. 

BEIJING, Aug. 19, 2025 /PRNewswire/ — Masanda is an ordinary young woman from Myanmar working at Youngor (Ruili) Co., Ltd. She has a gentle and simple personality and is quite shy. During her shifts, she works diligently, and in her leisure time, like her fellow Myanmar coworkers, she listens to music, sings, and dreams of finding a boyfriend she likes, hoping to create a life of her own.

The year 2025 marks the 75th anniversary of the establishment of diplomatic relations between China and Myanmar. The two countries are connected by shared mountains and rivers, and their peoples have maintained a friendship across generations, bound by the profound “pauk-phaw” bond. As Zhang Bo, the workshop director of this company, explained, she understands “pauk-phaw” as “sincerity for sincerity” in human interactions. Masanda and this group of young people from neighboring Myanmar, in the prime of their youth, have experienced firsthand in China what “pauk-phaw” truly means.

We captured the most vibrant details of their daily lives through our lens. Please watch the third episode of the micro-documentary series The Asian Century, titled Myanmar Workers in China.

The Asian Century is a social and cultural documentary series centered on the theme of building an Asian community with a shared future. Through authentic, multidimensional, and comprehensive storytelling, it showcases the shared historical roots, cultural bonds, and developmental aspirations of Asian nations.

https://www.youtube.com/watch?v=QdQkgGr_iyY

SINGAPORE, Aug. 19, 2025 /PRNewswire/ — 123 Food Pte Ltd, Singapore’s only MUIS halal-certified cuttlefish snack manufacturer, is accelerating its regional expansion across Southeast Asia. Building on its recent export success in Brunei and past exports to East Malaysia, the company is now actively seeking distribution partners in Indonesia, Thailand, and Mainland Malaysia to meet growing demand for halal-certified heritage snacks made in Singapore.

With increasing regional interest in quality snacks that combine tradition, authenticity, and food safety, 123 Food is uniquely positioned to scale. Backed by a strong track record in OEM and private label production, the brand is now offering exclusive distribution opportunities and custom production partnerships across Asia.

“We’re excited to connect with partners who value quality, halal certification, and the rich food heritage of Singapore,” said Shannon Lee, Director of 123 Food Pte Ltd. “Our goal is to bring Singapore’s beloved cuttlefish snacks to a new generation of snack lovers across the region.”

From Heritage Recipes to Modern Production: A Legacy Carried Forward

Founded in 2017, 123 Food Pte Ltd took over the recipes and traditional snack preparation methods passed down from the older generation of local snack makers. These time-honoured techniques, such as manually rolling cuttlefish through sugar cane presses and grilling over charcoal, are part of Singapore’s broader snack heritage, inspiring the brand’s commitment to preserving authentic flavours.

In the 1950s to 1970s, cuttlefish sheets were cut into squares and pasted onto tikam tikam boards, a nostalgic nod to childhood street-side games that left many fond memories for generations of Singaporeans. These playful yet humble beginnings laid the foundation for the brand’s enduring identity, reminding today’s consumers of the deep cultural roots behind each snack.

While 123 Food has modernised its operations, the artisanal craft remains at the heart of production. Today, high-efficiency baking and conveyor ovens ensure consistency and scalability, while decades of seasoning know-how from previous generations continue to deliver bold, umami-packed flavours that honour its heritage.

The Only MUIS Halal-Certified Cuttlefish Snack in Singapore

All products are proudly made in Singapore, manufactured under strict adherence to the country’s renowned food safety and hygiene regulations. With ISO22000:2018 certification and MUIS halal certification, 123 Food upholds the highest quality standards trusted by both distributors and consumers. This reputation as a Singapore-made product gives the brand a competitive edge in regional markets, where “Made in Singapore” is synonymous with reliability, cleanliness, and premium quality.

Made without preservatives or MSG, and seasoned with only natural ingredients, 123 Food’s products come in a variety of flavours and textures, crispy or chewy, spicy or sweet, ensuring appeal to a wide market base.

Flexible B2B Solutions, OEM and Private Label Services

123 Food Pte Ltd partners with a growing list of supermarkets, minimarts, distributors, and wholesalers. The company offers OEM and private-label solutions to help partners introduce halal-certified heritage snacks under their own branding. With the recent closure of several local cuttlefish snack producers, 123 Food is uniquely positioned to fill the gap and meet increasing regional demand.

Businesses looking to expand their product portfolio, explore exclusive distribution agreements, or request custom samples are welcome to connect.

Preserving Singapore’s Snack Culture, One Pack at a Time

Every pack from 123 Food is a celebration of Singapore’s rich culinary history. The brand bridges the past with the present and brings beloved seafood jerky into the hands and mouths of new generations. Proudly made in Singapore and grounded in decades of authenticity, the company continues its mission to share local flavours with the world.

For business enquiries, OEM/private label production, or to explore distribution opportunities with 123 Food Pte Ltd, contact:

Email: sales@123food.sg

About 123 Food Pte Ltd

123 Food Pte Ltd is Singapore’s only local halal-certified cuttlefish snack manufacturer, dedicated to honouring local snack heritage and delivering high-quality products made with natural ingredients. Proudly “Made in Singapore,” the company leverages the nation’s strict food safety and hygiene standards to provide products trusted by both domestic and regional markets. 123 Food partners with distributors across Singapore, Brunei, and East Malaysia, while continuing to expand its reach throughout Southeast Asia with OEM and private-label production.

123 Food Official Website

• Focus on empowering Urban Solutions and Sustainability to solve the world’s most essential, urgent challenges
• Pioneered a new AI screening platform to enhance the discovery of disruptive startups
• Record global participation with S$2.5 million+ prize pool 

SINGAPORE, Aug. 19, 2025 /PRNewswire/ — Singapore Management University (SMU) has announced the 60 finalists of the 12th Lee Kuan Yew Global Business Plan Competition (LKYGBPC), marking a milestone year as Singapore celebrates its 60th anniversary. Organised by SMU’s Institute of Innovation and Entrepreneurship (IIE), the biennial competition set new records for global participation, reaffirming its status as one of Asia’s largest university-led startup competitions.

This year’s Grand Finals Week will be held from 29 September to 2 October 2025 at SMU’s city campus, where finalists will compete for a prize pool of over S$2.5 million. Startups will compete across 12 focus areas, including Climate Tech, Energy Transition, Sustainable Materials, Urban Mobility, and Public Health.

The competition continues to attract global attention, receiving over 1,500 applications from more than 1,200 universities across 91 countries – a 57% increase from 2023. Entries from Asia grew by 70%.

“This reflects growing confidence in Singapore as a business and technology gateway to Asia,” said Shirley Wong, Entrepreneur-in-Residence at SMU IIE and Chairperson of the LKYGBPC Advisory Committee. “Hosting the competition alongside SG60 and the Singapore Grand Prix amplifies its energy and global reach, making it a powerful platform for entrepreneurs to connect and co-create.”

Many see Singapore as a regional springboard for growth. Evangelos Moschos, Co-Founder and CTO of Amphitrite, said, “Singapore is the world’s busiest transhipment hub where we can access shipping lines, investors, and a world-class R&D ecosystem. We’re also keen to hire Singaporean talent, including SMU students.”

New to this edition is the DueAI™ Challenge, which uses AI to streamline startup evaluation, reflecting trends in global venture capital. “DueAI™ shows how AI can scale and enhance objectivity in entrepreneurial evaluation,” said Dr Sze Tiam Lin, Senior Licensing Advisor at IIE.

The Grand Finals Week will feature roundtables with influential business families, an inaugural Talent Exchange linking students to global deep tech startups, and Blaze Mixer Night, an open networking event for Singapore’s youth to meet the founders.

The 12th LKYGBPC also welcomes A*STAR as its first Scientific Knowledge Partner and introduces new awards, including the Future of Sustainable Materials Award by Indorama Ventures, tapping its end-to-end R&D and manufacturing expertise to spotlight breakthrough materials innovations, and the Zhang Fan Global AI Initiative Award, empowering startups pushing boundaries in AI. This edition also witnessed growing support from investors including Antler, TRIREC, and Wavemaker Partners.

“Over the years, LKYGBPC has attracted bold founders from around the world, reinforcing Singapore’s role as a rising global hub for entrepreneurship,” said Paul Santos, Managing Partner of Wavemaker Partners. “It aligns with our mission to back companies solving meaningful problems and creating lasting impact.”

• Beyfortus (nirsevimab) is the only option that can offer RSV protection designed for all infants with proven high, sustained efficacy, favourable safety and public health impact demonstrated in the real world.^[1]
• In the recent HARMONIE trial findings, Beyfortus reduced RSV hospitalisations in infants by 82.7% (95% CI: 67.8 to 91.5; p<0,0001) through six months (180 days). ^{[2], [3]}
• Administration can be timed during the first year of life to provide protection from birth, or as early as possible.

SINGAPORE, Aug. 19, 2025 /PRNewswire/ — The Health Sciences Authority (HSA) has approved Sanofi and AstraZeneca’s BEYFORTUS (nirsevimab) for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in newborns and infants born during or entering their first RSV season, and for children up to 24 months of age who remain vulnerable to severe RSV disease through their second RSV season.

Globally, around 2 in 3 babies will catch RSV before their first birthday^[4] and it remains the most common cause of lower respiratory tract disease, including bronchiolitis and pneumonia, in infants^[5]. RSV is also a leading cause of hospitalisation among infants in Singapore, with most cases occurring in otherwise healthy, full-term babies. Each year, approximately 1,804 children under 29 months are hospitalised due to RSV-related illness^[6-10].

A panel of leading paediatricians in Singapore recently published an expert consensus, underscoring the urgent need for RSV protection in all infants. They concur that nirsevimab is key to alleviating the RSV burden on the healthcare system and recommend that immunisation be considered for all infants under the National Immunisation Programme in Singapore.^[11]

Zainab Sadat, Head of Vaccines, Sanofi Southeast Asia & India

“Today, Singapore joins other countries worldwide where an innovative immunisation solution is now available to protect all infants against RSV. The approval of BEYFORTUS marks a critical step towards giving parents the ability to protect their babies during their first year of life, when they are most vulnerable to severe RSV disease. We are committed to working with stakeholders across the RSV care continuum to ensure seamless implementation and broad availability of this innovative preventive solution — because every baby needs protection. Our goal is simple: to help parents protect their babies, and give them peace of mind.” 

The approval was based on results from the extensive BEYFORTUS clinical development programme spanning three pivotal late-stage clinical trials. Across all clinical endpoints, a single dose of BEYFORTUS demonstrated high and consistent efficacy against RSV disease sustained for at least five months. BEYFORTUS was well tolerated with a favourable safety profile that was consistent across all clinical trials. The overall rates of adverse events were comparable between BEYFORTUS and placebo and the majority of adverse events were mild or moderate in severity.

In temperate countries, the single administration of BEYFORTUS was developed to correspond with the beginning of the RSV season for babies born prior to the season or at birth for those born during the RSV season. In clinical trials, BEYFORTUS helped prevent RSV disease requiring medical care in all infant populations studied, including those born healthy, at term or preterm, or with specific health conditions that make them vulnerable to severe RSV disease. RSV disease requiring medical care included physician office, urgent care, emergency room visits and hospitalisations.

About RSV

RSV is a highly contagious virus that can lead to serious respiratory illness for infants.^[5] It is a leading cause of hospitalisation in all infants, with most hospitalisations for RSV occurring in otherwise healthy infants born at term^[6-10]. Two out of three infants are infected with RSV during their first year of life and almost all children are infected by their second birthday^[4]. Globally, in 2019, there were approximately 33 million cases of acute lower respiratory infections leading to more than three million hospitalisations, and it was estimated that there were 26,300 in-hospital deaths of children younger than five years^[12]. RSV-related direct medical costs, globally — including hospital, outpatient and follow-up care — were estimated at €4.82 billion in 2017^[13]. 

About BEYFORTUS

BEYFORTUS (nirsevimab) is the first immunisation designed for all newborns and infants for protection against RSV disease through their first RSV season, including for those born healthy at term or preterm, or with specific health conditions. It is also indicated for children up to 24 months of age who remain vulnerable to severe RSV disease through their second RSV season. 

As a long-acting antibody provided directly to newborns and infants as a single dose, BEYFORTUS offers rapid protection to help prevent lower respiratory tract disease caused by RSV without requiring activation of the immune system. BEYFORTUS administration can be timed to coincide with the RSV season.

BEYFORTUS has been approved for use in the European Union, the US, China, Japan, and many other countries around the world. Special designations to facilitate expedited development of BEYFORTUS were granted by several regulatory agencies, including Breakthrough Therapy Designation and Priority Review designation by The China Center for Drug Evaluation under the National Medical Products Administration; Breakthrough Therapy Designation and Fast Track Designation from the US Food and Drug Administration; access granted to the European Medicines Agency (EMA) PRIority MEdicines (PRIME) scheme and EMA accelerated assessment; Promising Innovative Medicine designation by the UK Medicines and Healthcare products Regulatory Agency; and BEYFORTUS has been named “a medicine for prioritized development” under the Project for Drug Selection to Promote New Drug Development in Pediatrics by the Japan Agency for Medical Research and Development.

About the clinical trials

The Phase 2b trial^[14] was a randomised, placebo-controlled trial designed to measure the efficacy of BEYFORTUS against medically attended lower respiratory tract disease (LRTD) caused by RSV through 150 days post-dose in healthy preterm infants of 29 to less than 35 weeks’ gestation (n=1,453). Infants were randomised (2:1) to receive a single 50 mg intramuscular injection of BEYFORTUS (n=969) or placebo (n=484) regardless of weight at the RSV season start. The primary endpoint was met, significantly reducing the incidence of medically attended RSV LRTD by 70.1% (95% CI: 52.3, 81.2; P<0.001) compared to placebo. In a prespecified secondary endpoint, BEYFORTUS reduced medically attended RSV LRTD with hospitalisation by 78.4% (95% CI 51.9, 90.3) versus placebo.

The BEYFORTUS dosing regimen was determined based on further exploration of the Phase 2b data and was used in subsequent trials as a single 50 mg dose for infants who weigh less than 5 kg, or a single 100 mg dose for those who weigh 5 kg or greater. A post-hoc analysis of the Phase 2b study that applied the recommended 50 mg dose in a subgroup of infants weighing less than 5 kg showed the efficacy of BEYFORTUS against medically attended RSV LRTD and medically attended RSV LRTD with hospitalisation was 86.2% (95% CI 68.0, 94.0) and 86.5% (95% CI 53.5, 96.1), respectively.

The Phase 3 MELODY trial^[15] was a randomised, double-blind, placebo-controlled trial conducted across 21 countries designed to determine the safety and efficacy of BEYFORTUS against medically attended LRTD caused by RSV in healthy term and late preterm infants (35 weeks gestational age or greater) entering their first RSV season, including efficacy against severe disease such as hospitalisation, through 150 days after dosing. The primary endpoint was met, reducing the incidence of medically attended RSV LRTD by 74.5% (95% CI 49.6, 87.1; P<0.001) compared to placebo. The efficacy of BEYFORTUS against the secondary endpoint of hospitalisation was 62.1% (-8.6, 86.8). A pre-specified pooled analysis of the Phase 3 MELODY trial showed the efficacy of BEYFORTUS against medically attended RSV LRTD and medically attended RSV LRTD with hospitalisation was 79.5% (95% CI 65.9, 87.7; P<0.0001) and 77.3% (95% CI 50.3, 89.7; P<0.001), respectively.

MEDLEY was a Phase 2/3^[16], randomised, double-blind, palivizumab-controlled trial with the primary objective of assessing safety and tolerability for BEYFORTUS in preterm infants of less than 35 weeks’ gestational age and infants with congenital heart disease (CHD) and/or chronic lung disease (CLD) of prematurity eligible to receive palivizumab. Between July 2019 and May 2021, a total of 925 infants at higher risk for severe RSV disease entering their first RSV season were randomised to receive BEYFORTUS or palivizumab. Safety was assessed by monitoring the occurrence of treatment emergent adverse events (TEAEs) and treatment emergent severe adverse events (TESAEs) through 360 days post-dose. Serum levels of BEYFORTUS following dosing (on day 151) in this trial were comparable with those observed in the Phase 3 MELODY trial, indicating similar protection in this population to that in healthy term and late preterm infants is likely.

BEYFORTUS was well tolerated with a favourable safety profile that was similar to palivizumab in the MEDLEY Phase 2/3 trial and consistent with the safety profile in healthy term and preterm infants compared to placebo across the MELODY and Phase 2b trials. The overall rates of adverse events were comparable between BEYFORTUS and placebo and the majority of adverse events were mild or moderate in severity.

The results of MELODY, Phase 2/3 MEDLEY and the Phase 2b trials illustrate that BEYFORTUS helped prevent RSV disease requiring medical care in all infant populations studied, including those born healthy at term or preterm, or with specific health conditions that make them vulnerable to severe RSV disease. RSV disease requiring medical care included physician office, urgent care, emergency room visits and hospitalisations.^[11]

These trials form the basis of regulatory submissions that began in 2022.

Another study, the Hospitalized RSV Monoclonal Antibody Prevention (HARMONIE) trial^{[2], [3]}, was a large European interventional clinical trial in 250 sites and including over 8,000 infants aiming to determine the efficacy and safety of a single intramuscular (IM) dose of BEYFORTUS (<5 kg 50 mg; ≥5 kg 100 mg), compared to no intervention (standard of care), for the prevention of hospitalisations due to RSV-related LRTD in infants under 12 months of age who are not eligible to receive palivizumab.

The data from HARMONIE show that BEYFORTUS reduced the incidence of hospitalisations due to RSV-related LRTD by 82.7% (95% CI: 67.8-91.5; p<0.0001) through 180 days after administration compared to no intervention, exceeding the typical length of the five-month RSV season. The high efficacy of 83.2% previously reported in the primary analysis was sustained over the longer follow-up period with no evidence of waning protection in infants born before or during the RSV season. BEYFORTUS maintained a favorable safety profile, consistent with clinical study results. ^{[2], [3]}

About Sanofi

Sanofi is an R&D driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time.

For more information, visit www.sanofi.com.

Sanofi Forward-Looking Statements  

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words “expects”, “anticipates”, “believes”, “intends”, “estimates”, “plans” and similar expressions. Although Sanofi’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates, the fact that product candidates if approved may not be commercially successful, the future approval and commercial success of therapeutic alternatives, Sanofi’s ability to benefit from external growth opportunities, to complete related transactions and/or obtain regulatory clearances, risks associated with intellectual property and any related pending or future litigation and the ultimate outcome of such litigation, trends in exchange rates and prevailing interest rates, volatile economic and market conditions, cost containment initiatives and subsequent changes thereto, and the impact that pandemics or other global crises may have on us, our customers, suppliers, vendors, and other business partners, and the financial condition of any one of them, as well as on our employees and on the global economy as a whole. The risks and uncertainties also include the uncertainties discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under “Risk Factors” and “Cautionary Statement Regarding Forward-Looking Statements” in Sanofi’s annual report on Form 20-F for the year ended December 31, 2022. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements.

References  

1. Beyfortus® Product Prescribing Information for Singapore.
2. Drysdale SB, Cathie K, Flamein F, Knuf M, Collins AM, Hill HC, Kaiser F, Cohen R, Pinquier D, Felter CT, Vassilouthis NC, Jin J, Bangert M, Mari K, Nteene R, Wague S, Roberts M, Tissières P, Royal S, Faust SN; HARMONIE Study Group. Nirsevimab for Prevention of Hospitalizations Due to RSV in Infants. N Engl J Med. 2023 Dec 28;389(26):2425-2435. doi: 10.1056/NEJMoa2309189.
3. Munro APS, Drysdale SB, Cathie K, Flamein F, Knuf M, Collins AM, Hill HC, Kaiser F, Cohen R, Pinquier D, Vassilouthis NC, Carreno M, Moreau C, Bourron P, Marcelon L, Mari K, Roberts M, Tissières P, Royal S, Faust SN; HARMONIE Study Group. 180-day efficacy of nirsevimab against hospitalisation for respiratory syncytial virus lower respiratory tract infections in infants (HARMONIE): a randomised, controlled, phase 3b trial. Lancet Child Adolesc Health. 2025 Jun;9(6):404-412. doi: 10.1016/S2352-4642(25)00102-6.
4. Walsh, EE. Respiratory Syncytial Virus Infection: An Illness for All Ages. Clinics in Chest Medicine. 2017;38(1):29-36.
5. Karron A. Respiratory Syncytial Virus Vaccines and Monoclonal antibodies. Orenstein W, Offit P, Edwards KM, Plotkin S. Plotkin’s Vaccines, eighth edition: 998-1004. Elsevier 2023.
6. Leader S, Kohlhase K. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. J Pediatr. 2003;143(5 Suppl):S127-S132. doi:10.1067/s00223476(03)00510-9.
7. Zhou H, et al. Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993-2008. Clin Infect Dis. 2012;54:1427–1436.
8. Rha B, et al. Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016. Pediatrics. 2020;146:e20193611.
9. Arriola CS, et al. Estimated Burden of Community-Onset Respiratory Syncytial Virus-Associated Hospitalizations Among Children Aged <2 Years in the United States, 2014-15. J Pediatric Infect Dis Soc. 2020;9:587-595
10. Tam CC, et al. Burden and Cost of Hospitalization for Respiratory Syncytial Virus in Young Children, Singapore. Emerg Infect Dis. 2020 Jul;26(7):1489-1496
11. Goh, D.Y.T., Goh, A., Chen, C.K. et al. Expert consensus on the burden of respiratory syncytial virus disease and the utility of nirsevimab for disease prevention and protection of infants. World J Pediatr 21, 552–565 (2025). https://doi.org/10.1007/s12519-025-00926-2
12. Li Y, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet 2022;399:92047–64.
13. Zhang S, et al. Cost of Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection Management in Young Children at the Regional and Global Level: A Systematic Review and Meta-Analysis. J Infect Dis. 2020;222(Suppl 7):S680-687.
14. Simões EAF, Madhi SA, Muller WJ, Atanasova V, Bosheva M, Cabañas F, Baca Cots M, Domachowske JB, Garcia-Garcia ML, Grantina I, Nguyen KA, Zar HJ, Berglind A, Cummings C, Griffin MP, Takas T, Yuan Y, Wählby Hamrén U, Leach A, Villafana T. Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials. Lancet Child Adolesc Health. 2023 Mar;7(3):180-189. doi: 10.1016/S2352-4642(22)00321-2. Epub 2023 Jan 9. 
15. Hammitt LL, Dagan R, Yuan Y, Baca Cots M, Bosheva M, Madhi SA, Muller WJ, Zar HJ, Brooks D, Grenham A, Wählby Hamrén U, Mankad VS, Ren P, Takas T, Abram ME, Leach A, Griffin MP, Villafana T; MELODY Study Group. Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants. N Engl J Med. 2022 Mar 3;386(9):837-846. doi: 10.1056/NEJMoa2110275.
16. Domachowske J, Madhi SA, Simões EAF, Atanasova V, Cabañas F, Furuno K, Garcia-Garcia ML, Grantina I, Nguyen KA, Brooks D, Chang Y, Leach A, Takas T, Yuan Y, Griffin MP, Mankad VS, Villafana T; MEDLEY Study Group. Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity. N Engl J Med. 2022 Mar 3;386(9):892-894. doi: 10.1056/NEJMc2112186.

Issued on behalf of Sanofi Singapore by IN.Deed Communications.
For more information:
Jar Wong | +65 9188 3227 | jar@indeedcommunications.com
Janet Han | +6012-2363 460 | janet@indeedcommunications.com