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Ascletis Announces ASC47, a Muscle-Preserving Weight Loss Drug Candidate for Treatment of Obesity, Demonstrated Greater Efficacy with Tirzepatide than Semaglutide in a Preclinical Model

–         The combination of ASC47 low dose with tirzepatide in diet-induced obese (DIO) mice resulted in an 87% greater reduction in body weight compared to tirzepatide monotherapy.

 –          ASC47 low dose in combination with tirzepatide demonstrated statistically significantly greater increase in efficacy than ASC47 low dose in combination with semaglutide, 87% vs 55%, respectively, in the DIO mouse model.

–          The combination of ASC47 low dose with tirzepatide also restored the body composition of obese mice to the level of healthy non-obese mice.  At the end of treatment, the percentage of total muscle mass over the total body weight of obese mice treated with the combination of ASC47 low dose with tirzepatide was similar to healthy non-obese mice, 60.4% vs 62.0% respectively.

HONG KONG, Aug. 13, 2025 /PRNewswire/ — Ascletis Pharma Inc. (HKEX:1672, “Ascletis”) announces encouraging efficacy results from its study in diet-induced obese (DIO) mice combining ASC47, a first-in-class muscle-preserving weight loss drug candidate for the treatment of obesity, with tirzepatide.

ASC47 is an adipose-targeted, once-monthly subcutaneously (SQ) injected thyroid hormone receptor beta (THRβ) selective small molecule agonist, discovered and developed in-house at Ascletis. ASC47 possesses unique and differentiated properties to enable adipose targeting, resulting in dose-dependent high drug concentrations in the adipose tissue.

The objective of the DIO mouse study was to compare a low dose of ASC47 (9 mg/kg, single dose) combined with tirzepatide (3 nmol/kg, SQ, once daily) against tirzepatide monotherapy (3 nmol/kg, SQ, once daily). The treatment duration in the DIO mice was 14 days. Results showed that the combination of ASC47 low dose with tirzepatide was superior to tirzepatide monotherapy, with an average total body weight reduction of 38.1% compared to 20.4%, achieving 87% more relative weight loss compared to tirzepatide monotherapy (Table 1). In comparison, the combination of ASC47 low dose with semaglutide demonstrated statistically significantly lower efficacy  (p=0.006)  in the DIO mouse study, showing a 55% greater reduction in body weight compared to semaglutide monotherapy.

Table 1. ASC47 low dose demonstrated greater efficacy with tirzepatide than semaglutide

Group

Dosing

Total body

weight change
from baseline

Greater body weight
reduction of combination
vs monotherapy

Obese mice treated
with tirzepatide

Tirzepatide,

3 nmol/kg,

SQ, QD

-20.4 %

Obese mice treated
with ASC47 low
dose combination
with tirzepatide

ASC47,

9 mg/kg,

SQ, a single dose

+

tirzepatide,

3 nmol/kg,

SQ, QD

-38.1%

(p<0.0001 vs
tirzepatide monotherapy)

87 %

Obese mice treated
with semaglutide

Semaglutide,

30 nmol/kg,

SQ, QD

-23.1 %

Obese mice treated
with ASC47 low
dose combination
with semaglutide

ASC47,

9 mg/kg,

SQ, a single dose

+

semaglutide,

30 nmol/kg,

SQ, QD

-35.9%

(p<0.0001 vs
semaglutide monotherapy

55 %

Note: Treatment duration: 14 days for tirzepatide monotherapy and ASC47/tirzepatide combination therapy; 28 days for semaglutide monotherapy and ASC47/semaglutide combination therapy; Obese mice: diet-induced obese mice; SQ: subcutaneous; QD: once daily.

The combination of ASC47 low dose with tirzepatide also restored the body composition of obese mice to the level of healthy non-obese mice.  At the end of treatment, the percentage of total muscle mass over the total body weight of obese mice treated with ASC47 low dose and tirzepatide (60.4%) was similar to healthy non-obese mice (62.0%), indicating healthy weight loss. Tirzepatide monotherapy was unable to restore body composition to healthy levels.

“These preclinical data build upon a body of evidence demonstrating the potential of ASC47 as an important therapeutic approach for the treatment of obesity.” said Jinzi Jason Wu, Ph.D., Founder, Chairman and CEO of Ascletis, “With topline data in participants with obesity from the combination study of ASC47 with semaglutide coming soon, we look forward to the combinations of ASC47 with other incretin drugs including tirzepatide in future clinical trials.”

About Ascletis Pharma Inc.

Ascletis Pharma Inc. is a fully integrated biotechnology company focused on the development and commercialization of potential best-in-class and first-in-class therapeutics to treat metabolic diseases. Utilizing its proprietary Artificial Intelligence-Assisted Structure-Based Drug Discovery (AISBDD) Platform and Ultra-Long-Acting Platform (ULAP), Ascletis has developed multiple drug candidates in-house, including its lead program, ASC30, a small molecule GLP-1R agonist in development as a once-daily oral tablet and once-monthly subcutaneous injection for weight management. Ascletis is listed on the Hong Kong Stock Exchange (1672.HK).

For more information, please visit www.ascletis.com.

Contact:

Peter Vozzo
ICR Healthcare
443-231-0505 (U.S.)
Peter.vozzo@icrhealthcare.com

Ascletis Pharma Inc. PR and IR teams
+86-181-0650-9129 (China)
pr@ascletis.com
ir@ascletis.com

Daesang’s Jongga Launches Collaborative Menus with Popular Restaurants in the U.S. and Australia

  • Partnering with Rokstar Chicken and Kochi in New York and CHAE in Australia, to debut bold kimchi-crafted creations
  • Kimchi-inspired chicken sandwiches, bibimbap, and fine dining courses winning over consumers worldwide

SEOUL, South Korea, Aug. 13, 2025 /PRNewswire/ — Daesang announced on 13th that its kimchi brand, Jongga, is teaming up with renowned restaurants in the United States and Australia to launch an innovative range of kimchi-forward dishes.

Daesang Jongga Restaurant Collaboration - (From left) Rokstar Chicken's Jongga Kimchi Chicken Sandwich & French Fries, KOCHI's Jongga Kimchi Bibimbap, CHAE’s Official Collaboration Poster
Daesang Jongga Restaurant Collaboration – (From left) Rokstar Chicken’s Jongga Kimchi Chicken Sandwich & French Fries, KOCHI’s Jongga Kimchi Bibimbap, CHAE’s Official Collaboration Poster

As the global K-Food craze continues, interest in kimchi—the quintessential representative of Korean cuisine—is on the rise. To share kimchi’s appeal with a wider range of global consumers, Daesang has teamed up with celebrated international restaurants to create new menus. By partnering with popular local establishments across diverse formats—from casual franchises to fine dining and traditional Korean cuisine—the company aims to showcase the versatility of Jongga Kimchi to a broad customer base.

Rokstar Chicken, the rising star of New York’s dining scene, is redefining Korean-style fried chicken with bold flavors and a modern edge, embodied in its slogan, Korean Flavor, New York Attitude. Through this collaboration, the Jongga Kimchi Chicken Sandwich and Jongga Kimchi French Fries will be available at its five New York locations through March next year. The menu items were first previewed at the Head in the Clouds Los Angeles 2025 global music festival in June, and received an enthusiastic response from local attendees. In addition, the two brands plan to produce co-branded T-shirts and tableware featuring the Jongga and Rokstar Chicken emblems for use in-store.

Another highlight is Jongga’s collaboration with Kochi in New York, a Korean fine dining restaurant specializing in skewer-based courses. Kochi earned one Michelin star in 2021 and is helmed by Chef Sungchul Shim, formerly of the three-Michelin-starred Per Se restaurant. Beginning in September and running through August next year, Kochi will serve its signature bibimbap topped with finely chopped Jongga Mat Kimchi, offered as the Jongga Kimchi Bibimbap. The two brands are also working to jointly develop new products using Jongga Kimchi.

In Melbourne, Australia, the acclaimed Korean restaurant CHAE will present a special kimchi-themed course menu during October and November. Each course will feature kimchi at different stages of fermentation, offering a multi-dimensional flavor experience—from appetizers made with fully fermented kimchi to later dishes incorporating younger, less-fermented kimchi. Reservations for the October menu will open in early August via CHAE’s official website, with November reservations opening in early September, and diners will be selected by lottery each month. From December through July next year, Jongga Kimchi will be served as part of CHAE’s standard banchan (side dish) offerings, and in the second half of next year, the restaurant will host a hands-on kimchi-making workshop (Kimjang Workshop).

Through these collaborations, Daesang’s Jongga is elevating kimchi from a humble side dish to a gourmet centerpiece, showcasing its limitless potential to audiences worldwide. The brand will broaden its reach through partnerships with top dining destinations worldwide.

Lee Kyung-ae, Head of Daesang’s Global Kimchi Business Division, stated, “As Korea’s No. 1 kimchi brand, Jongga seeks to create more opportunities for global consumers to experience and enjoy kimchi in authentic and exciting ways. We will continue to collaborate with renowned restaurants to develop unique menu items and innovative products that highlight the health benefits and culinary appeal of Jongga Kimchi in the global market.”

Meanwhile, to meet the surging demand for kimchi in the U.S. and European markets, Daesang became the first Korean food company to operate a large-scale kimchi production facility in Los Angeles in 2022, and is currently building a new plant in Kraków, Poland. Jongga products are sold through major retail channels across the U.S. and Europe, including not only original kimchi but also locally tailored varieties that reflect the food culture and consumption trends of each market. As the world’s No. 1 packaged kimchi brand, Jongga actively promotes the excellence and appeal of kimchi through consumer engagement initiatives including pop-up stores, cooking competitions, and appearances at music festivals. 

MindHYVE.ai Partners with ICS Pakistan and NEI Pakistan to Revolutionize Nursing Education with AI-Powered ArthurAI

ISLAMABAD, Aug. 13, 2025 /PRNewswire/ –In a pioneering step towards elevating nursing education in Pakistan, MindHYVE.ai has signed strategic Memorandum of Understanding (MoU) with the Institute of Contemporary Studies (ICS) and the National Excellence Institute (NEI).

MindHYVE.ai, ICS, and NEI Forge Partnership to Revolutionize Nursing Education in Pakistan with AI-Powered ArthurAI™
MindHYVE.ai, ICS, and NEI Forge Partnership to Revolutionize Nursing Education in Pakistan with AI-Powered ArthurAI™

Pakistan faces a critical shortage of nursing professionals, with approximately 0.47 nurses and midwives per 1,000 people—significantly below the World Health Organization’s recommended minimum of 2.5 per 1,000 (World Bank, 2019; International Labour Organization). In clinical settings, the ideal nurse-to-patient ratio is 3 nurses for every 10 patients, yet many facilities operate with fewer, affecting care quality and increasing workforce strain (Pakistan Nursing Council).

ArthurAI™ licenses will initially target 2,000 nursing students within the first year, scaling to 10,000 nursing students within two years. Over the longer term, MindHYVE.ai aims to empower 80,000 nurses nationwide with ArthurAI™, positioning this collaboration as a transformative force in Pakistan’s nursing education and healthcare workforce development. Bill Faruki, CEO of Mindhyve.ai stated “Our partnerships with ICS and NEI reflect a shared commitment to harness AI’s power in shaping the future of healthcare education in Pakistan. ArthurAI™ will empower both students and educators to achieve unprecedented levels of personalization, efficiency, and academic success.” Mohammad Aurangzeb Nadeem, Executive Director of ICS and NEI added “We are excited to pioneer AI-driven transformation in nursing education. This unified effort will strengthen our academic programs, enhance student outcomes, and support Pakistan’s healthcare sector with skilled nursing professionals ready for tomorrow’s challenges.”

About ICS & NEI Pakistan

ICS, a leading private-sector institution, hosts and delivers the Post-RN BSN nursing program for Khyber Medical University, focusing on inclusive education and AI-enhanced curriculum development. NEI, a specialized healthcare education institute, advances nursing excellence and digital innovation by embedding ArthurAI™ as a virtual assistant within its Post-RN BSN program.

About MindHYVE.ai™

MindHYVE.ai™ is redefining the boundaries of intelligence by engineering autonomous systems and deploying domain-specific AGI agents across real-world sectors. Powered by the Ava-Fusion™ large reasoning model and architected for agent coordination, swarm intelligence, and adaptive autonomy, MindHYVE’s technology stack is revolutionizing law, medicine, finance, education, and governance.

With operations in North America, Asia, and in Africa, MindHYVE.ai™ is on a mission to democratize access to transformative intelligence and architect the infrastructure for post-scarcity economies. Backed by HYVE Labs, the company continues to shape the future of agentic systems on a global scale.

Website: www.mindhyve.ai | Email: hello@mindhyve.ai | Contact: +1 (949) 200-8668

Media Contact
Marc Ortiz
Email: marc.ortiz@mindhyve.ai

 

CGTN AMERICA & CCTV UN: “Echoes of Peace” Event to Mark the 80th Anniversary of WWII End

WASHINGTON, Aug. 13, 2025 /PRNewswire/ — CGTN America & CCTV UN releases “Echoes of Peace” Event to Mark the 80th Anniversary of WWII End.

“Echoes of Peace” cultural exchange event in New York City features global delegations, veterans, and unique multimedia experiences to commemorate the 80th anniversary of the end of World War II and the founding of the United Nations. The event, which is scheduled to take place at 8 p.m. ET on August 13 at the UN Headquarters, aims to honor the heroes, reflect on resilience, and reaffirm the principles of peace that have guided the international community for eight decades.

Delegations from approximately 30 countries, including United Nations officials, representatives for WWII veterans, and diplomats, will attend the cultural exchange event.

The program feature keynote speeches from prominent figures from China, the U.S. and the United Nations. Musicians will perform “Tennessee” from the film Pearl Harbor, capturing the bittersweet essence of love in the shadow of war. They will also present “Flowers of Peace,” a tribute to hope and the triumph over adversity.

An impressive mapping projection will be displayed on the side wall of the Secretariat Building. The projection will visually narrate the world’s journey toward peace and the establishment of the United Nations. The UN Headquarters complex in New York City was officially inaugurated on January 9, 1951. The iconic Secretariat Building was completed in 1950. These buildings embody the post-WWII international community’s shared vision of peace and cooperation, grounded in the ideals of the UN Charter and Universal Declaration of Human Rights.

Presented by China Media Group, “Echoes of Peace” cultural exchange event underscores the ongoing importance of the United Nations in fostering global peace and cooperation.

(This material is distributed by MediaLinks TV, LLC on behalf of CCTV. Additional information is available at the Department of Justice, Washington, D.C.)

Contact : Distribution@cgtnamerica.com

GameChange Solar Rises to Third Globally and Second in U.S. Solar Tracker Market

NORWALK, Conn., Aug. 13, 2025 /PRNewswire/ — GameChange Solar has solidified its position as one of the world’s leading solar tracker manufacturers, ranking third globally and second in the United States in the latest Global Solar PV Tracker Market Share Report 2025 from Wood Mackenzie.

In 2024, GameChange Solar shipped 13.7 GWdc of trackers, securing a 26% share of the U.S. market—its highest-ever U.S. ranking and maintaining a strong global footprint. The company also achieved notable success internationally, ranking second in India with 3.9 GWdc of shipments, and second in Africa due to major projects in South Africa and Egypt, both key drivers of its global performance.

“Reaching second place in the U.S. and holding third globally is a powerful milestone that reflects our relentless focus on delivering reliable, high-performance tracker solutions with a rock-solid supply chain,” said Phillip Vyhanek, President and COO of GameChange Solar. “It’s proof that when you combine innovative technology with rapid, dependable project delivery, you can reshape markets and help accelerate the global transition to clean energy.”

GameChange’s global growth is supported by a 35 GW U.S. manufacturing footprint and over 50 GW of total global manufacturing capacity, along with operational facilities in key markets including India and Saudi Arabia. The company’s flagship Genius Tracker® product line—featuring 1P, 2P, and two-row 1P configurations—was its most popular technology in 2024, designed for rapid installation, terrain adaptability, and optimized energy yield.

Looking ahead, GameChange plans to continue scaling its global operations, advancing tracker technology, and delivering value to customers across the utility-scale solar sector.

About GameChange Solar

GameChange is one of the top three global providers of solar tracker solutions used in utility-scale and ground-mounted distributed generation solar projects around the world. We have delivered over 43 GW of solar tracker and fixed tilt systems that combine fast installation, bankable quality, and unbeatable value through superior engineering, innovative design, and high-volume manufacturing. Our products enable solar panels at power plants to follow the sun’s movement across the sky, optimizing plant performance while protecting the array from damaging weather conditions.

For more information, visit www.gamechangesolar.com

Contact:
Lisa Andrews
Director of Marketing
GameChange Solar
lisa.andrews@gamechangesolar.com

 

Public Interest Registry Announces 2025 .ORG Impact Awards Finalists, Artist & Actor Common to Host

35 innovative, mission-driven organizations and changemakers selected from nearly 3,000 applicants across more than 120 countries

RESTON, Va., Aug. 13, 2025 /PRNewswire/ — Public Interest Registry (PIR), the people behind the .ORG domain, named the finalists for the 7th annual .ORG Impact Awards on Tuesday and announced that philanthropist and activist Common will host this year’s awards ceremony in Washington, D.C. The .ORG Impact Awards recognize outstanding mission-driven individuals and organizations from around the world for their positive contributions to society.

All finalists, which range from a women-led nonprofit transforming lives in East Africa, to an organization recycling hair into tools to help the environment, to a .ORG using AI to teach sign language across Latin America, will receive donations of $2,500 USD. All 35 finalists will also be invited to Washington, D.C. for a celebration that includes opportunities to meet with other nonprofit leaders and culminates with the final award ceremony on October 7.

“The .ORG Impact Awards continues to be one of the most meaningful initiatives we look forward to all year, and I’m honored to welcome the extraordinary 2025 finalists to our global .ORG Community. These finalists represent the very best of our community — their dedication and impact embody the very spirit of the .ORG domain,” said Jon Nevett, President and CEO of Public Interest Registry. “We’re thrilled to have Common join us and help uplift the forward-thinking changemakers honored at this year’s awards. A long-time advocate for criminal justice and youth empowerment, Common is a changemaker himself and brings a powerful voice to this celebration of purpose-driven work.”

Common is an award-winning rapper and actor: the first rapper to win a Grammy, Oscar and Emmy and star of the Apple TV+ show Silo. He is also the founder of the nonprofit Free to Dream, which works across four pillars — education, justice, wellness, and jobs — to create the conditions necessary for these dreams to come true. From Art in Motion charter school in Chicago to enrichment programs that take place in schools, communities, and prisons, Free To Dream is dismantling the school-to-prison pipeline at both ends helping people of all ages reclaim their life’s true trajectory. Free To Dream reflects 20 years of Common’s leadership as a changemaker, using his entertainment platform to advance critical social causes.

“I’m passionate about making sure youth in the U.S. are able to see positive role models and pathways to achieve their dreams, especially those involved in the justice system, so it’s inspiring to see people from all over the world creating positive change for the next generation in their communities,” said Common. “I’m excited to celebrate the hard work of these organizations and individuals creating powerful change at this year’s .ORG Impact Awards.”

This year’s finalists represent the top five entries across seven award categories:

  • Community Building
  • Quality Education for All
  • Environmental Stewardship
  • Diversity, Equity, and Inclusion
  • Health and Healing
  • Hunger and Poverty
  • Rising Stars (leaders under 30 making a difference in their communities)

Winners in these award categories and the prestigious .ORG of the Year, will be announced as part of the in-person .ORG Impact Awards celebration on October 7. The winner of the .ORG of the Year award will receive a donation of $50,000 USD while the other category winners will each receive $10,000 USD. Beyond the donation, receiving a .ORG Impact Award will help raise the profile of winning organizations, ultimately driving donations, funding, talent acquisition, partnership development, and increasing audience reach.

Please visit www.orgimpactawards.org for more information.

2025 .ORG Impact Award Finalists

Community Building

Empower Mali
empowermali.org
Empower Mali improves lives in rural Malian communities through clean water, education, agriculture, and solar energy, with a focus on community co-investment and long-term sustainability.

Fonds pour les Femmes Congolaises (The Fund for Congolese Women)
www.ffcrdc.org
Fonds pour les Femmes Congolaises funds and strengthens grassroots women’s organizations in the DRC to advance peace, justice, and gender equality from the ground up.

Long Way Home
lwhome.org
Long Way Home engages people in democracy and creates economic and environmental justice through green building, employment, and education.

Techo
techo.org
TECHO is a youth-led organization working in Latin America’s informal settlements, mobilizing volunteers and communities to overcome poverty through housing, civic engagement, and community-building programs that promote dignity and social justice.

Well Aware
wellawareworld.org
Well Aware is a women-led nonprofit transforming lives in East Africa through sustainable, community-driven clean water systems that advance health, education, and gender equity.

Quality Education for All

Central Leadership Academy
centralleadershipacademy.org
Central Leadership Academy delivers holistic education rooted in community, leadership, and innovation, transforming learning access for underserved youth and children in Liberia and beyond.

INCLUDEU
incluedu.org
IncluEdu uses AI to teach sign language and equip educators with inclusive tools, offering real-time feedback and fostering deaf inclusion in schools, workplaces, and communities across Latin America.

Rocket Learning Foundation
rocketlearning.org
Rocket Learning uses tech to connect parents, teachers, and governments in India, improving foundational learning and early childhood education at scale.

NABU
nabu.org
NABU aims to solve the global literacy crisis. By providing culturally relevant, bilingual storybooks in mother tongue languages, NABU ensures that every child can read and rise to their full potential.

Yellow Boat of Hope Indonesia
yellowboat-id.org
Yellow Boat of Hope Indonesia builds boats, clean water systems, scholarships, and volunteer-led learning to help children in remote coastal communities access education and opportunity.

Environmental Stewardship

Matter of Trust
matteroftrust.org
Matter of Trust connects surplus with need. Their flagship program recycles hair into tools that regenerate soil and clean water, empowering communities in 52+ countries through circular, nature-based solutions for climate resilience and restoration.

Nature Environment and Wildlife Society (NEWS)
naturewildlife.org
NEWS restores and protects mangrove ecosystems by co-creating with communities, nurturing women climate leaders, and promoting nature-based livelihoods, advancing biodiversity and climate resilience across India.

Ocean Alliance, Inc.
whale.org
Ocean Alliance protects whales and their ocean environment through global research, education, and innovative drone tech based in Gloucester, Massachusetts.

Wandusoa Organic Cameroon Development Association
wandusoa.org
Wandusoa trains marginalized youths and smallholder farmers in regenerative agriculture and business skills, cultivating socially and ecologically responsible entrepreneurs in rural Cameroon.

The Welman Project
thewelmanproject.org
The Welman Project diverts surplus materials from landfills and redistributes them to schools and nonprofits, supporting education, sustainability, and creativity.

Diversity, Equity, and Inclusion

Found in Translation
found-in-translation.org
Found in Translation trains low-income bilingual women as medical interpreters, advancing health equity and economic mobility in underserved communities.

Humanos 3D
humanos3d.org
Humanos 3D provides personalized assistive devices for people with upper limb disabilities using 3D printing and emerging technologies, fostering inclusion, innovation, and education through community driven impact.

Imkaan Welfare Organization
imkaan.org
Imkaan Welfare Organization empowers marginalized, undocumented, and stateless communities—especially women and children—through education, healthcare, vocational and digital learning, economic opportunities, and legal aid, fostering dignity and inclusion.

Purnata
purnata.org
Purnata rescues and rehabilitates trafficking survivors in India, providing safe spaces, education, jobs, and long-term care to break the cycle of exploitation.

Red Dot Global Foundation
reddotfoundation.org
Red Dot Foundation crowdsources data on sexual violence through its Safecity platform, using local insights to promote safety, justice, and survivor-led change.

Health and Healing

Access to Specialist Knowledge
accesstospecialistknowledge.org
Access to Specialist Knowledge connects healthcare workers in underserved regions of the globe to U.S. board-certified medical specialists, offering pro bono support that empowers local providers and promotes equitable access to healthcare.

The BIG Fix Uganda
thebigfixuganda.org
The BIG FIX Uganda provides lifesaving vet care, animal welfare education, free rabies vaccines, and Africa’s first animal-assisted trauma therapy program—pairing war survivors with rescued dogs to heal PTSD, promote compassion, and transform communities in Northern Uganda.

Global Response Medicine
global-response.org
Global Response Medicine provides emergency medical care and professional training to populations affected by conflict and disaster, deploying veteran-led teams to high-risk areas to save lives.

Nunchi Health
nunchihealth.org
Nunchi Health reimagines youth mental health by centering cultural identity, peer leadership, and community healing. They provide free, accessible, and affirming support to immigrant and minority youth often excluded from traditional systems.

Tiba Foundation
tibafoundation.org
Tiba Foundation partners with Kenyan health organizations to strengthen rural clinics, train providers, and improve women’s economic empowerment and access to life-saving healthcare.

Hunger and Poverty

Andando
andando.org
Andando helps rural Senegalese communities break the cycle of poverty by focusing on long-term partnerships and the growth of the whole village through integrated support in water, health, education, agroforestry, and financial independence.

Kula Project
kulaproject.org
Kula partners with Rwandan coffee farmers to build thriving farms and sustainable incomes through agricultural training and entrepreneurial development.

Manna Cafe Ministries
mannacafeministries.org
Manna Café Ministries serves the hungry and hurting in Tennessee by providing essentials, support services, and opportunities rooted in dignity, wellness, and community.

MicroLoan Foundation USA
microloanfoundationusa.org
MicroLoan Foundation USA alleviates poverty and promotes gender equality for women in sub-Saharan Africa by providing microfinance, business training, and savings support to help them build resilient livelihoods and transform their families’ futures.

The Rahul Kotak Foundation
therahulkotakfoundation.org
The Rahul Kotak Foundation transforms children’s lives in Kenya by tackling school hunger, advancing menstrual health and expanding access to education in underserved communities.

Rising Stars

Aworanti Salvation Grace, Voices Against Rape and Sexual Harrassment Foundation
varshfoundation.org
VARSH Foundation empowers women and girls across Africa through feminist-led leadership, advocacy, and legal aid to end sexual and gender-based violence and promote peace.

Joshua Williams, Joshua’s Heart Foundation
joshuasheart.org
Joshua’s Heart Foundation trains the next generation of hungry leaders by equipping service-oriented students with the strategic vision, operational skill-set, and trusted network they need to combat food insecurity and poverty in their own communities.

Jovia Kisaakye, Ecobed Biotech Brand
ecobedbiotech.org
Ecobed Biotech transforms food waste into mosquito-repellent lotion, clean fuel, and organic farm inputs, advancing climate resilience, health, and livelihoods across East Africa.

Nicholas Lowinger, Gotta Have Sole
gottahavesole.org
Gotta Have Sole’s mission is to provide under-resourced youth with brand new shoes to help them feel confident, comfortable, and special. They are opening opportunities for kids to go to school, play sports, and be kids.

Zofia Kierner, Girls Future Ready Foundation 
girlsfutureready.org
Girls Future Ready builds confidence and professional skills in young women across Central and Eastern Europe through global mentorship and education programs.

.ORG of The Year

The 2025 .ORG Impact Award, .ORG of the Year, recognizes an outstanding nonprofit or nongovernmental organization nominated in one of the seven categories for their incredible achievement in the past year as evidenced by results and contributions to their sector, constituents, community or society at large. The winner will be announced on October 7.

About Public Interest Registry
Public Interest Registry (PIR) is a nonprofit that operates the .ORG top-level domain—one of the world’s largest generic top-level domains with more than 11 million domain names registered worldwide. .ORG is open to everyone, providing a global platform for organizations, associations, clubs, businesses and individuals to bring their ideas to life. PIR has been a champion for a free and open Internet for two decades with a clear mission to be an exemplary domain name registry, provide a trusted digital identity and help educate those who dedicate themselves to improving our world. PIR was founded by the Internet Society (internetsociety.org) in 2002 and is based in Reston, Virginia, USA. Visit www.pir.org for more information.

Media contact: pir@berlinrosen.com
Contact: Shane Tan, shane.tan@berlinrosen.com, (718) 883-0699

VivaVision Strengthens Scientific Advisory Board with a World-Renowned Expert in Ophthalmology

WENZHOU, China, Aug. 13, 2025 /PRNewswire/ — Recently, VivaVision Biotech (Zhejiang) Co., Ltd. (VivaVision) announced the appointment of Quan Dong Nguyen, MD, MSc, FAAO, FARVO, FASRS to its Scientific Advisory Board.

Quan Dong Nguyen, MD, MSc, FAAO, FARVO, FASRS, is currently a professor of ophthalmology at the Byers Eye Institute, Stanford University School of Medicine; he is also a professor of medicine (immunology and rheumatology) and professor of pediatrics at Stanford. Dr. Nguyen serves as principal investigator on multiple clinical trials sponsored by the National Eye Institute and other organizations for macular edema (from diabetes and uveitis), neovascular AMD, and ocular inflammatory and uveitic diseases, as well as co-investigator on numerous clinical trials involving novel therapeutic agents. Professor Nguyen was among the first clinician scientists in the world to evaluate the safety and efficacy of aflibercept for neovascular AMD and ranibizumab for diabetic macular edema (DME), which became the foundation for subsequent trials leading to FDA approval of anti-VEGF therapy for retinal vascular diseases. He also led other trials, including READ-2, READ-3, and iDEAL studies for diabetic macular edema and SAVE, SAVE-2, STOP-UVEITIS, SATURN, ACTHAR, and ATLAS, and recently LEOPARD and LION studies for uveitis and ocular inflammatory diseases. Dr. Nguyen received both B.S. and M.Sc. in Molecular Biophysics and Biochemistry from Yale and M.D. from the University of Pennsylvania Perelman School of Medicine. He completed his internship in Internal Medicine at the Massachusetts General Hospital and residency in ophthalmology at the Massachusetts Eye and Ear Infirmary, Harvard Medical School. Dr. Nguyen also obtained fellowships in Uveitis as well as Vitreoretinal Surgery at the Massachusetts Eye and Ear Infirmary, and Ocular Immunology at the Wilmer Eye Institute, Johns Hopkins University. Dr. Nguyen is a member of many prestigious organizations, including the Macula Society, the Retina Society, the American Society of Retina Specialists, the Club Jules Gonin, the American Ophthalmological Society, the Association for Research in Vision and Ophthalmology, the International Uveitis Study Group, the Foster Ocular Immunology Society, and the American Uveitis Society, among others. Professor Nguyen is the current President of the International Ocular Inflammation Society, which is the largest society in the world devoted to ocular inflammation.

Dr. Wang Shen, Founder and Chief Executive Officer of VivaVision Biotech, stated:

“We are very honored to welcome Professor Quan Dong Nguyen as a member of VivaVision Biotech’s Scientific Advisory Board (SAB). Professor Quan Dong Nguyen’s expertise and extensive experience in diabetic/uveitis-related macular edema, neovascular age-related macular degeneration (AMD), and intraocular inflammatory diseases will help VivaVision to further its innovative pipeline. In particular, we look forward to collaborating with Professor Quan Dong Nguyen on our dual JAK1/TYK2 inhibitor VVN461 (an ophthalmic solution) and VVN481 (a suspension for suprachoroidal injection). VivaVision will continue to strengthen its capabilities in R&D innovation, advance its pipeline both in China and abroad, and establish ourselves as a global leader in ophthalmic drug discovery.”

“It is a tremendous pleasure for me to join the Scientific Advisory Board at VivaVision,” said Professor Nguyen. “I believe that VivaVision’s JAK1/TYK2 inhibitor has the potential to be a novel therapeutic option for patients who are using and dependent on corticosteroids of different routes of administration for their ocular inflammatory diseases. I look forward to advising the Company on the clinical programs and trial preparation and the development of promising therapeutic candidates in the future.”

About VivaVision Biotech

Founded in 2016, VivaVision Biotech is a clinical-stage pharmaceutical company dedicated to advance first-in-class and best-in-class therapies for ocular diseases. The company’s leading pipeline assets include:

  • VVN461: non-steroidal dual JAK1/TYK2 immunomodulator for post-operative inflammation after cataract surgery and non-infectious anterior uveitis.
  • VVN001: an investigational treatment for dry eye disease.
  • VVN1901: a therapy for neurotrophic keratitis
  • VVN481: a non-steroidal dual JAK1/TYK2 inhibitor for suprachoroidal injection to treat posterior/pan-uveitis and posterior inflammatory diseases

In addition to its pipeline, VivaVision is actively engaged in the discovery and development of innovative therapies for anterior and posterior ocular diseases to address unmet patient needs. For more information, please visit www.vivavisionbio.com.

RepTrak Appoints Thierry D’Hers and Catherine Hernandez-Blades to Board of Directors

BOSTON, Aug. 12, 2025 /PRNewswire/ –The RepTrak Company™, the world’s leading provider of reputation intelligence, proudly announces the appointment of Thierry D’Hers and Catherine Hernandez-Blades to its Board of Directors. These strategic appointments underscore RepTrak’s commitment to scaling its reputation intelligence suite with cutting-edge technologies, AI-driven insights, and product innovation. 

Thierry D’Hers  

Thierry D’Hers brings more than two decades of experience in product innovation, engineering leadership, and advisory roles. He is most known for his foundational role at Tableau, where he helped scale the company’s data visualization platform, PowerBI, into a global business intelligence leader. Most recently, he served as Chief Product & Engineering Officer at Vivun. D’Hers has also advised several tech organizations including Pigment, Radar, Indico Labs, and Headwaters Economics — holding strategic roles in both enterprise and mission-driven technology ventures.  

“RepTrak is uniquely positioned at the intersection of technology, data, and trust,” said D’Hers. “I’m excited to join the Board at a time when innovation and AI are reshaping how organizations manage stakeholder perception. I look forward to aiding the growth of the world’s most powerful reputation intelligence platform.” 

Catherine Hernandez-Blades

Catherine Hernandez-Blades holds a distinguished track record across the financial services, defense, aerospace, technology, and government sectors. She currently serves as an independent board director for CoreCivic, Inc., where she sits on the Nominating & Governance and Risk Committees.  

Previously, she held C-suite roles at three Fortune 500 companies: Chief Marketing and Communications Officer at SAIC, Aflac, and Flex. In addition, she is an EMMY® winner, Cannes Lions recipient, Forbes Top 50 Global CMO, and the first and only American recipient of the Relations 4 the Future medal at Davos.  

“Having relied on RepTrak’s products and services for over a decade across multiple Fortune 500 companies, I can personally attest to the platform’s immense value. It not only quantifies the business impact driven by teams but also plays a crucial role in strategic decision-making — extending its influence to the entire C-suite and Board of Directors. I’m particularly excited about the innovative new products in development and am delighted to join RepTrak’s board.”  

Fueling Product and Platform Evolution 

These appointments reflect a deliberate move to accelerate the evolution of RepTrak’s recently launched platform, Compass™ — deepening its technology, product, governance, and communications expertise. D’Hers and Hernandez-Blades bring strengths that will help guide RepTrak through its next phase of growth and innovation. 

“Thierry and Catherine bring distinct and deeply aligned expertise to RepTrak. Thierry’s product and AI leadership, paired with Catherine’s global reputation leadership, governance insight, and ESG acumen, position us to serve clients with sharper intelligence, deeper trust, and greater value than ever before. We are proud to welcome them both to the Board” says Mark Sonders, CEO of The RepTrak Company.

About The RepTrak Company  

The RepTrak Company is the world’s premier provider of reputation data and insights, helping businesses harness reputation intelligence to secure competitive advantage. RepTrak’s predictive insights enable subscribers to safeguard business value, optimize ROI, and amplify their positive societal impact. Combining advanced metrics with dedicated reputation advisors, RepTrak delivers actionable analyses that align business goals with stakeholder sentiment across global markets and diverse industries.  

Established in 2004, The RepTrak Company owns the world’s largest reputation benchmarking database, gathering over 1 million company ratings per year used by CEOs, boards, and executives in more than 60 countries worldwide.  

For more information, please visit www.reptrak.com.  

About RepTrak Compass 

Compass is the only truly integrated global solution for reputation intelligence — combining RepTrak’s world-class Global Advisory expertise with AI-enabled navigation. Designed for today’s dynamic stakeholder environment, Compass enables leaders to shift from measuring reputation to actively shaping it. 

RepTrak invites communications, corporate affairs, brand, and reputation leaders around the world to explore Compass — and see how it empowers them to lead reputation, not just report on it.  

To learn more about Compass, visit https://www.reptrak.com/compass