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Cellid Selected for Google for Startups’ “Founders at Campus” Program

Selected as one of the initial members of the Tokyo-based “Founders at Campus” program  

TOKYO, Aug. 15, 2025 /PRNewswire/ — Cellid Inc., a company developing AR glasses displays and spatial recognition engines for next-generation devices, is pleased to announce that it has been selected for “Founders at Campus,” a startup support initiative hosted by “Google for Startups.”

“Founders at Campus” is a global initiative by “Google for Startups” that provides innovative startups with access to the “Google for Startups Tokyo Campus” community hub, enabling them to leverage Google’s knowledge, network, and infrastructure to support their global expansion. The “Google for Startups Campus” has hubs in six cities around the world, one of which is in Tokyo. These hubs provide a workspace where entrepreneurs can collaborate and connect with one another, as well as host various events to foster networking.

Recently, Cellid was selected as one of the initial members of “Founders at Campus,” a new initiative launched by the Tokyo hub of “Google for Startups Tokyo Campus.” This recognition reflects the high evaluation of the growth potential and innovation of the AR glasses and related technologies developed by our company.

Comment from Satoshi Shiraga, CEO, Cellid

“Cellid is currently working to bring AR glasses into mainstream use and is accelerating the development of next-generation AR glasses. Access to the Android ecosystem and collaboration with the global developer community are extremely important factors for our future business development. With our selection for ‘Founders at Campus,’ we will further expand our technical verification and ecosystem from a global perspective to deliver valuable AR experiences to more people.”

About Cellid

Cellid specializes in the development of advanced AR glass display modules, focusing on waveguides and spatial recognition engines for next-generation devices. Leveraging unique optical simulation and proprietary production technologies, Cellid has developed display modules as thin and lightweight as standard eyeglass lenses, delivering clear images and one of the world’s largest fields of view for waveguides. Additionally, Cellid offers industry-specific solutions powered by spatial recognition technologies such as Cellid SLAM. By integrating cutting-edge AR display hardware with real-world spatial recognition software, Cellid is driving the “Blending of Physical and Digital World,” making exceptional information tools more accessible, practical, and convenient for users worldwide.

  

Tie “James” Li, Chairman of NMHI, To Speak at XRP Seoul 2025 Global Conference

ONTARIO, Calif., Aug. 15, 2025 /PRNewswire/ — Tie “James” Li, Chairman and CEO of Nature’s Miracle Holding Inc. (OTCQB:NMHI) will attend the XRP Seoul 2025 Global Conference as a keynote speaker on September 21, 2025.

XRP SEOUL 2025 hosted by XRPL Korea is a global conference bringing together XRP holders, developers, and ecosystem projects from around the world. Taking place on September 21, 2025, the event features sessions on market outlooks, Web3 go-to-market strategies, and the evolving regulatory landscape. There will be over 3,000 attendees and over 100 companies from 40 countries.

According to James LI, chairman and CEO of Nature’s Miracle, “We are pleased to be invited and look forward to participating in this major XRP conference. I am very excited to share our XRP vision with the conference participants.” Mr. Li added “We are very cognizant that Korean is the largest XRP community outside the U.S., holding over 25 billion of XRP. This venue is ideal to promote our XRP business and to seek partners. “

About Nature’s Miracle Holding Inc.

Nature’s Miracle (www.Nature-Miracle.com) is a growing agriculture technology company providing products and services to growers in the Controlled Environment Agriculture (“CEA”) industry in the U.S.  The Company’s Common Stock trades on the OTCQB market (“OTCQB”) under the symbol “NMHI”.

Forward-Looking Statements

The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: the intended use of proceeds from the offering; successful launch and implementation of Nature’s Miracle’s joint projects with manufacturers and other supply chain participants of steel, rubber and other materials; changes in Nature’s Miracle’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; Nature’s Miracle’s ability to develop and launch new products and services; Nature’s Miracle’s ability to successfully and efficiently integrate future expansion plans and opportunities; Nature’s Miracle’s ability to grow its business in a cost-effective manner; Nature’s Miracle’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of Nature’s Miracle’s business model; developments and projections relating to Nature’s Miracle’s competitors and industry; and Nature’s Miracle’s approach and goals with respect to technology.

These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the quotation of the Company’s shares on the OTC; changes in applicable laws or regulations; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which Nature’s Miracle’s operates; the risk that Nature’s Miracle’s and its current and future collaborators are unable to successfully develop and commercialize Nature’s Miracle’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that Nature’s Miracle’s is unable to secure or protect its intellectual property; the possibility that Nature’s Miracle’s may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in Nature’s Miracle’s filings from time to time with the SEC.

Origin Agritech Hosts Industry Summit in Zhengzhou, Strengthens Distribution Network with Over 700 Partners

BEIJING, Aug. 15, 2025 /PRNewswire/ — Origin Agritech Ltd. (NASDAQ: SEED) (the “Company” or “Origin”), a leading Chinese agricultural technology company, today announced the successful completion of its Achievements Exhibition and Seed Industry Innovation Summit held in Zhengzhou, Henan Province on August 9-10, 2025. The summit attracted over 700 distributor partners from across China and more than 30 industry experts, reinforcing Origin’s market position and advancing its strategic growth initiatives.

The two-day event served as a comprehensive platform for showcasing Origin’s latest product portfolio, including four new corn varieties: Jingke 317, Jinqiao 8, Xundan 203, and Aoyu 728. Field demonstrations provided distributors with direct exposure to the agronomic performance of these varieties, which have progressed through multi-year testing protocols and regulatory approvals across multiple provinces.

Strong Distributor Engagement and Market Response

The summit demonstrated significant market interest in Origin’s new product offerings, with distributors actively participating in the new product launch and ordering process. The Company’s ability to convene over 700 distribution partners underscores the strength of its established channel network and the commercial appeal of its product pipeline.

“This summit represents a strategic milestone in our distribution network expansion,” said Weibin Yan, Chief Executive Officer of Origin Agritech. “The strong attendance from our channel partners and their engagement in the ordering process validates our product development strategy and market positioning.”

Product Portfolio and Regulatory Progress

The featured varieties showcase Origin’s continued R&D capabilities:

  • Jinqiao 8: Approved for introduction in five provinces (certificate no.: Anhui: Wan Shen Yu 20211001; Jiangsu: Su Yin Zhong 2022-059, Shandong: Lu Yin Zhong 2022078, Henan: Yu Yin Zhong 2022 Yu 096; Hubei: E Yin Zhong 2023131)
  • Jingke 317: Approved in National Trial (certificate no. Guo Shen Yu 20243348)
  • Aoyu 728: Approved in National Trial  (certificate no. Guo Shen Yu 20226136)
  • Xundan 203: Approved in Henan Province (certificate no. Yu Shen Yu 20242023)

Under the leadership of Vice President and R&D Director Dezhi Deng, Origin’s breeding programs continue to focus on developing varieties with enhanced stress tolerance, yield optimization, and commercial viability suited to China’s diverse agricultural conditions.

Strategic Initiatives and Market Expansion

During the summit, CEO Weibin Yan outlined Origin’s eight-year strategic development plan, emphasizing the Company’s commitment to building a leading position in China’s seed industry. The event also marked the launch of the “Golden Harvest Club,” a strategic alliance designed to strengthen relationships within Origin’s distribution ecosystem.

The summit featured expert presentations from leading agricultural researchers, including Professor Dai Jingrui from China Agricultural University, Chief Corn Scientist Wang Haiyang from Yazhou Bay National Laboratory, and Researcher Zhao Jiuran from Beijing Academy of Agricultural and Forestry Sciences, who endorsed the Jingke 317 variety he developed.

About Origin Agritech Limited

Origin Agritech Limited, founded in 1997 and headquartered in Origin R&D Center, Songzhuang, Tongzhou in Beijing, is a leading Chinese agricultural technology company. In crop seed biotechnologies, Origin Agritech’s phytase corn was the first transgenic corn to receive the Bio-Safety Certificate from China’s Ministry of Agriculture. Over the years, Origin has established a robust biotechnology seed pipeline, including products with glyphosate tolerance and pest resistance (Bt) traits. For further information, please visit the Company’s website at www.originagritech.com. The Company also maintains an X account for updating investors on Company and industry developments which is https://x.com/origin_agritech.

Forward-Looking Statements

This communication contains “forward-looking statements” as defined in the federal securities laws, including Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. Forward-looking statements address expected future business and financial performance and financial condition and contain words like “expect,” “anticipate,” “intend,” “plan,” “believe,” “seek,” “will,” “would,” “target,” and similar expressions and variations. Forward-looking statements address matters that are uncertain. Forward-looking statements are not guarantees of future performance and are based on assumptions and expectations that may not be realized. They are based on management’s current expectations, assumptions, estimates, and projections about the Company and the industry in which the Company operates but involve a number of risks and uncertainties, many of which are beyond the Company’s control. Some of the important factors that could cause the Company’s actual results to differ materially from those discussed in forward-looking statements are: failure to develop and market new products and optimally manage product life cycles; ability to respond to market acceptance, rules, regulations and policies affecting our products; failure to appropriately manage process safety and product stewardship issues; changes in laws and regulations or political conditions; global economic and capital markets conditions, such as inflation, interest and currency exchange rates; business or supply disruptions; natural disasters and weather events and patterns; ability to protect and enforce the Company’s intellectual property rights; and separation of underperforming or non-strategic assets or businesses. The Company undertakes no duty or obligation to publicly revise or update any forward-looking statements as a result of future developments, new information, or otherwise, should circumstances change, except as otherwise required by securities and other applicable laws. Although the Company believes that the expectations expressed in these forward-looking statements are reasonable, it cannot assure that such expectations will be correct. Actual results may differ materially from the anticipated results. You are urged to consider these factors carefully in evaluating the forward-looking statements contained herein. You are cautioned not to place undue reliance on such forward-looking statements, which are qualified in their entirety by these cautionary statements.

For more information, please contact:
Origin Agritech Limited Contact:
Kate Lang (Mandarin/English)
Director of Investor Relations
Phone: +86 186-1839-3368
Email: bing.lang@originseed.com.cn

Investor Relations Contact:
Matthew Abenante, IRC
President
Strategic Investor Relations, LLC
Tel: 347-947-2093
Email: matthew@strategic-ir.com

Awaken in Paradise: The Stunning Sunrise at TUI BLUE Tuy Hoa

TUY HOA, Vietnam, Aug. 15, 2025 /PRNewswire/ — Perched on the 17th floor of TUI BLUE Tuy Hoa, you will be treated to a stunning sunrise, painting the sky a brilliant orange over the East Sea. This unique view offers a profound sense of calm and connection, allowing guests to truly embrace their “Me Moments.”

Awaken in Paradise: The Stunning Sunrise at TUI BLUE Tuy Hoa
Awaken in Paradise: The Stunning Sunrise at TUI BLUE Tuy Hoa

The Serene Beauty of Tuy Hoa

Nestled peacefully on the South Central Coast, Tuy Hoa ward of DakLak province – is one of the rare places where time seems to slow down. Neither flashy nor bustling, this charming coastal ward is defined by its tranquil sea, gentle rice fields, and a leisurely pace of life as light as the wind. While some cities make us eager to explore, places like Tuy Hoa invite us to simply stop, breathe deeply, and feel more than we think.

As evening falls, Nhan Tower sparkles like a lighthouse, and the curve of Chop Chai Mountain appears as a soft, artistic stroke against the sky. In the distance, the sea rests quietly under the horizon, a gentle note in the city’s peaceful melody.

A hotel renowned for wellness and retreats

Located in the city center, amidst majestic mountain scenery and vast rice fields, TUI BLUE Tuy Hoa is a luxury hotel with 221 modern rooms and suites. The highlight is the Lumiere Wellness & Healing Club on the second floor, which offers a unique Jjimjilbang service – a Korean sauna combining spa and wellness therapies. Here, guests can experience deep relaxation and detoxification across eleven dry, wet, hot, and cold sauna rooms.

Beyond relaxation, we encourage an active lifestyle. For those looking to stay active, our exclusive four-seasons swimming pool, pickleball, and tennis courts provide opportunities for friendly competition and energetic fun. At TUI BLUE Tuy Hoa, every moment is crafted for a revival of body and soul, promising a getaway that transcends mere rest.

Meet me at the beach!

Located just 50 meters from the vibrant Phu Yen Square, the TUI BLUE Tuy Hoa beach invites guests to discover a private oasis for ultimate tranquility and rejuvenation.

The recent opening of the Beach Front Bistro & Club marks a significant milestone for TUI BLUE Tuy Hoa, extending our commitment to offering unparalleled, personalized experiences. Imagine a place where the gentle murmur of the ocean complements the vast expanse of the sky, where pristine blue waters invite you for a refreshing dip, and every moment is crafted for pure bliss. This is the essence of our new beachfront haven.

Click here to download hi-res photo

SUNRATE Secures Payment Business Licence In China


SINGAPORE – Media OutReach Newswire – 15 August 2025 – SUNRATE, the global payment and treasury management platform, today announced it has secured a payment business licence in China following its successful acquisition of a 100% stake in Transfar Pay, a unit of Shenzhen-listed Transfar Group. The RMB 315 million (USD 43.8 million) acquisition has received approval from relevant Chinese regulatory authorities. This transaction had been previously announced by the Transfer Group in an exchange filing dated April 1, 2025.

“This acquisition represents a strategic step in SUNRATE’s ongoing commitment to enhancing our global licensing framework and ensuring compliant operations in all jurisdictions, whether through direct licensing or strategic partnerships,” said Paul Meng, co-founder at SUNRATE.

With the addition of this licence, SUNRATE gains greater access to one of the world’s most important and dynamic markets. This further complements SUNRATE’s regulatory presence in key jurisdictions including Singapore, Hong Kong SAR, the United Kingdom, and Indonesia, with further regulatory milestones in other jurisdictions to be announced in due course.

Hashtag: #SUNRATE

The issuer is solely responsible for the content of this announcement.

About SUNRATE

SUNRATE is a global payment and treasury management platform for businesses worldwide. Since its inception in 2016, SUNRATE has been recognised as a leading solution provider and has enabled companies to operate and scale both locally and globally in 190+ countries and regions with its cutting-edge proprietary platform, extensive global network, and robust APIs.

With its global business headquarters in Singapore and offices in Hong Kong, Jakarta, London, and Shanghai, SUNRATE partners with the top global financial institutions, such as Citibank, Standard Chartered, Barclays, J.P. Morgan and is the principal member of both Mastercard and Visa. To learn more about SUNRATE, visit

FINNS Bali Launches Future Nation, Featuring Bali’s First SAR Helicopter And A Beach Cleaning Robot

“Party Like There Is A Tomorrow”

BALI, Indonesia, Aug. 15, 2025 /PRNewswire/ — FINNS Bali, a leading Indonesian hospitality group and home to FINNS Beach Club, today announced the launch of FINNS Future Nation Day, a milestone one-day-only event designed to showcase the company’s growing commitment to sustainability, community impact, and responsible tourism across Indonesia.

FINNS FUTURE NATION PASSPORT
FINNS FUTURE NATION PASSPORT

Hosted at FINNS Beach Club in Canggu, FINNS Future Nation Day takes guests on a uniquely themed journey, from check-in through boarding, layovers, landing, and departure, to explore FINNS’ past, present, and future ESG work. The event highlights the company’s long-term investment in building a hospitality model where world-class entertainment aligns with environmental and social responsibility and paves the way for how leading hospitality brands play their part in tourism and community responsibility towards a better Bali.

As part of the event, FINNS will unveil two major ESG-led innovations to the public for the first time:

  • Bali’s first search and rescue helicopter was developed in partnership with SGI, an accredited leader in air medical transfers as well as search and rescue training and operations. This initiative will significantly enhance emergency response capabilities for both local residents and visitors on the island and surrounding areas, an exciting operation that is the first of its kind in Bali.
  • The BeBot beach-cleaning robot, a remote-controlled, electric innovation that collects microplastics and sand debris without disrupting the natural environment, is an exciting investment in FINNS’ already large-scale, existing waste and recycling operation.

These exclusive announcements underscore FINNS Bali’s leadership in environmental innovation, tourism safety, and long-term community stewardship.

ESG Impact Areas Featured at FINNS Future Nation Day:

  • Sustainability & Waste Reduction
    A behind-the-scenes look at FINNS’ waste diversion, recycling systems, and water conservation technologies. Check out how we have managed to divert 488,140kg of waste from landfills, and how we have recycled 82.3 million litres of water.
  • Community & Culture
    Programs focused on youth development, local employment, and cultural heritage preservation. Check out how we have donated over 12,000 essential items, with over 1,000 staff engaged in our efforts and 1,000 youth and children in need impacted, across Bali.
  • Responsible Innovation
    Showcasing smart technology, infrastructure investments, and partnerships that support Bali’s long-term environmental and tourism resilience.

About FINNS Bali:

Founded in 2010 and based in Bali, Indonesia, FINNS Bali is the parent company of several iconic lifestyle and hospitality venues, including FINNS Beach Club, FINNS Recreation Club and the future FINNS Bali Resort (opening 2026). The group is dedicated to creating unforgettable experiences for both residents and visitors of Bali.

FINNS Beach Club exists to deliver the world’s best beach club party experience, every single day. Known for its innovation, high standards, and commitment to community, FINNS Bali as a whole continues to redefine hospitality in Bali through passion, creativity, and a drive for excellence.

The company operates with a clear vision and strong values that guide every aspect of its journey. More than just venues, FINNS creates moments that guests carry with them long after their visit, experiences that are timeless, joyful, and deeply connected to the spirit of Bali.

With continued growth and the launch of the FINNS Bali Resort on the horizon, FINNS remains a leader in shaping the island’s hospitality and lifestyle landscape.

Discover TUI BLUE Tuy Hoa, Your Sanctuary for Relaxation in Central Vietnam

TUY HOA, Vietnam, Aug. 15, 2025 /PRNewswire/ — Discover a tranquil retreat infused with modern luxuries at TUI BLUE Tuy Hoa, a wellness-focused resort hotel. Begin your day with a stunning vista of Chop Chai Mountain and the historic Nhan Tower, where nature and culture intertwine seamlessly.

Discover TUI BLUE Tuy Hoa, Your Sanctuary for Relaxation in Central Vietnam
Discover TUI BLUE Tuy Hoa, Your Sanctuary for Relaxation in Central Vietnam

A Blissful Sanctuary for Mind and Body

Our dedication to wellness is evident in every facet of the hotel. Find your calm in the serene Tai Chi meditation garden, participating in rejuvenating yoga sessions that harmonize body and spirit. For a truly unique and therapeutic experience, indulge in the traditional Jjimjilbang, a Korean-style spa that promotes deep relaxation and detoxification with eleven dry and wet, hot and cold sauna rooms.

Beyond relaxation, TUI BLUE Tuy Hoa encourages an active lifestyle. Delight your palate at our exquisite on-site restaurants and bars, offering a culinary journey that complements your wellness goals. For those looking to stay active, our exclusive four seasons swimming pool, pickleball and tennis courts provide opportunities for light-hearted competition and energetic spirits. At TUI BLUE Tuy Hoa, every moment is crafted for a revival of body and soul, promising a getaway that transcends mere rest.

Embracing Nature And Local Heritage

At TUI BLUE Tuy Hoa, we take pride in authentically connecting our guests with the rich cultural heritage of Phú Yên. Through our curated BLUE® Experiences program, guests are invited to explore the region’s traditions, cuisine, and natural beauty in meaningful ways. We partner with local artisans, farmers, and cultural performers to bring hands-on activities, such as Vietnamese cooking classes, rice paper making, and local craft workshops, directly to our resort.

Our BLUE® Guides offer tailor-made excursions to iconic landmarks like Ganh Da Dia, Bai Xep, and the Mang Lang Church. On these tours, they share the stories, folklore, and history of this stunning coastal region. Our dining experiences further showcase the province’s culinary identity through farm-to-table menus that use locally sourced ingredients and traditional recipes with a modern twist.

The resort’s architecture and interior styling reflect local motifs and materials, fusing traditional Vietnamese elegance with modern luxury. By weaving these elements into the guest journey, we not only offer a deeper sense of place but also contribute to the preservation and promotion of the cultural heritage of Vietnam’s central coastal provinces.

Click here to download hi-res photo

Novel Gene Therapy for ALS cleared for global trials in China and the U.S.

BEIJING, Aug. 15, 2025 /PRNewswire/ — SineuGene Therapeutics Co., Ltd. (“SineuGene”), clinical-stage biotechnology company that mainly focuses on gene therapies for neurological disorders, announced today that China’s National Medical Products Administration (NMPA) has cleared the Investigational New Drug (IND) application for SNUG01, a groundbreaking gene therapy product for amyotrophic lateral sclerosis (ALS). This milestone follows a prior clearance of SNUG01’s IND application by the U.S. Food and Drug Administration (FDA) in March 2025, paving the way for the initiation of a Phase I/IIa multi-regional clinical trial (MRCT) in both China and the United States.

SNUG01 is a first-in-class recombinant adeno-associated virus serotype 9 (rAAV9) based gene therapy product that expresses the human TRIM72 protein (Tripartite Motif Protein 72), a new drug target for ALS initially identified and characterized by Dr. Yichang Jia’s group at Tsinghua University, upon delivery to the central nervous system (CNS), particularly motor neurons. This global Phase I/IIa trial will evaluate the safety and potential efficacy of SNUG01 and identify dosage for further clinical development in adults with ALS. The study will be conducted in multiple leading academic centers in both countries, including the Healey & AMG Center for ALS at Massachusetts General Hospital (U.S.), Peking University Third Hospital, the Second Affiliated Hospital of Zhejiang University School of Medicine and Fujian Medical University Union Hospital.

“The dual clearance accelerates and validates the strategy for the development of potentially transformative therapies for people with ALS worldwide”, said Professor Merit Cudkowicz, Director of the Healey & AMG Center for ALS at Massachusetts General Hospital and global principal investigator of the trial. “We are pleased to collaborate on this study and look forward to evaluating the therapy’s potential impact on patients living with ALS.”

The regulatory clearances that have been conducted in both the U.S. and China, demonstrating the momentum behind SNUG01’s global development. Through strategic collaborations and scientific rigor, SineuGene is advancing its first-in-class gene therapy to address the unmet and urgent needs of the global ALS community.

About SNUG01

SNUG01, developed by SineuGene via its proprietary AAV technology platform, is a first-in-class gene therapy product using TRIM72 as the gene of interest. TRIM72 was identified as a potential therapeutic gene based on foundational research from Dr. Yichang Jia’s lab at Tsinghua University. SNUG01 utilizes a rAAV9 vector to deliver the human TRIM72 to neurons via intrathecal administration. Preclinical studies have shown that TRIM72 expression could counteract ALS pathogenesis through multiple mechanisms, including reducing oxidative stress, enhancing neuronal membrane repair capacity, restoring mitochondrial homeostasis, inhibiting neuroinflammatory cascades, and suppressing stress granule dysregulation. This multi-dimensional action delays motor neuron degeneration in patients with ALS.

A recently completed investigator-initiated trial (IIT) in China demonstrated SNUG01’s favorable safety, along with early signs of clinical efficacy and biomarker improvements. Crucially, unlike ALS therapies targeting specific genetic mutations, SNUG01’s broad neuroprotective mechanism holds the potential to benefit the sporadic ALS patients —a population occupying over 90% of ALS patients and currently lacking effective treatment options. These promising results support SNUG01’s continued global development.

About ALS

ALS is a rapidly progressive neurodegenerative disorder marked by motor neuron degeneration in the brain and spinal cord, leading to muscle weakness, atrophy, and eventually respiratory failure. Median survival time is 3-5 years. Despite being the most prevalent adult-onset motor neuron disease, existing therapies offer limited clinical benefits, slowing progression marginally and leaving no curative options for patients.

About SineuGene

SineuGene Therapeutics Co., Ltd. is a clinical-stage biotech company pioneering innovative therapies, focusing on AAV-based and nucleic acid-based treatments, for neurological disorders. Founded in late 2021, the company’s initial pipeline was built upon foundational research led by Dr. Yichang Jia at Tsinghua University’s School of Medicine. SineuGene leverages cutting-edge technologies, such as adeno-associated virus (AAV) mediated gene delivery and antisense oligonucleotide (ASO) based gene regulation, to develop a robust pipeline targeting central nervous system disorders including ALS, Stroke, Parkinson’s Disease, Alzheimer’s Disease, Multiple System Atrophy (MSA), and Spinocerebellar Ataxia Type 3 (SCA3). SineuGene is committed to translating scientific discoveries into transformative therapies for patients worldwide with unmet and urgent medical needs.

Website: www.sineugene.com  
Contact:
Ms YAN, Siying
yansiying@sineugene.com