BOSTON, Jan. 22, 2025 /PRNewswire/ — Antennova, a clinical-stage biotech company focused on oncology today announced the presentation of latest data from its Phase I/II CLINCH study ongoing in China and Australia evaluating ATN-022 (CLDN18.2 antibody-drug conjugate [ADC]) in patients with advanced or metastatic gastric cancer at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium 2025 (ASCO GI 2025).

• The CLINCH study is a Phase I/II study ongoing in China and Australia with a dose escalation phase followed by a dose expansion phase. As of November 22, 2024, among 21 gastric cancer patients in dose expansion phase with CLDN 18.2 expression of IHC 2+ ≥ 20% who had at least 1 tumor evaluation, the overall response rate (ORR) was 42.9%, and the disease control rate (DCR) was 95.2% (9 partial responses [PRs] including 8 confirmed PRs; and 11 stable diseases [SDs]). 
• Among 10 gastric cancer patients with CLDN 18.2 expression of IHC 2+ < 20% treated at efficacious doses of 1.8 – 2.4 mg/kg, the ORR was 30.0% (1 complete response [CR] and 2 PRs, all PR/CR were confirmed with CLDN 18.2 expression of IHC 2+ < 5%), and the DCR was 50.0%. The patient with CR has demonstrated durable response and has been on the study for over 14 months as of the cut-off date.
• ATN-022 demonstrated a manageable safety profile and promising preliminary antitumor activity in late stage gastric cancer patients across various levels of CLDN18.2 expression, supporting further clinical investigations of ATN-022 in gastric cancer patients. The enrollment of gastric cancer patients for dose optimization and patients with other solid tumors is ongoing in China and Australia.

Details of the Poster Presentation:

ATN-022 (also known as ATG-022, CLDN18.2 antibody-drug conjugate)

Title: Safety and Preliminary Efficacy of ATG-022 in Patients with Advanced/Metastatic Gastric Cancer (CLINCH)

Abstract Number: 456

Session: Poster Session A: Cancers of Esophagus and Stomach and Other Gastrointestinal Cancers

Presenter: Jinfeng Ma  Shanxi Cancer Hospital

Date: Thursday, January 23, 2025

Time: 11:30 AM – 1:00 PM (Pacific time)

3:30 AM – 5:00 AM, January 24, 2025 (Beijing time)

About ATN-022

ATN-022 is an antibody-drug conjugate (ADC) designed to target CLDN18.2, a member of the Claudin family of cell adhesion molecules. Under normal conditions, Claudins are located within tight junctions between cells, forming a barrier to regulate cell permeability. However, in cancer, Claudins are aberrantly expressed on the cell surface due to changes in cell polarity. CLDN18.2 is frequently overexpressed in a range of primary malignant tumors, including gastric, esophageal, cholangiocarcinoma, pancreatic and other cancers. The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug Designations to ATN-022, for gastric and pancreatic cancers.

Data from the ongoing CLINCH study of ATN-022 has shown promising clinical efficacy in gastric cancer patients with various levels of CLDN18.2 expression. The efficacy already observed across all levels of CLDN18.2 expression in patients with gastric cancer suggests that ATN-022 holds the promise as a competitive treatment option.

About Antennova

Antennova, a Delaware corporation and a subsidiary of Antengene (HKEX: 6996), is a clinical-stage biotech company specialized in developing innovative therapeutics that target the critical biological mechanisms that enable cancers to evade and resist treatment by current drugs. Antennova is developing a pipeline of oncology candidates that can potentially enhance the effectiveness of standard therapies.

Forward-Looking Statements

The forward-looking statements made in this document relate only to the events or information as of the date on which the statements are made in this document. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this document completely and with the understanding that our actual future results or performance may be materially different from what we expect. In this document, statements of, or references to, our intentions or those of any of our Directors or our Company are made as of the date of this document. Any of these intentions may alter in light of future development.

For more information, please contact:

Investor Relations
Email: ir@antennova.com

BANGKOK, Jan. 22, 2025 /PRNewswire/ — Thailand is set to make a grand debut at Expo 2025 Osaka, Kansai, Japan, highlighting the country’s commitment to becoming one of the global leaders in medical and wellness services. In line with the Expo’s theme “Designing Future Society for Our Lives,” Thailand will demonstrate how its unique blend of traditional practices and advanced medical services fosters the greatest happiness and well-being for all.

Promoting Thailand as a Preferred Global Medical Hub

According to Thailand’s Minister of Public Health Somsak Thepsutin, the World Expo provides an exceptional opportunity for nations to connect and showcase innovations that shape a better future.

“We are excited to take part in this global event, where Thailand will share its unmatched expertise in both traditional Thai medicine and modern healthcare,” Minister Somsak stated. “Thailand’s policies are focused on transforming the country into an international medical hub, and our participation in Expo 2025 in Osaka will highlight our strengths in these areas.”

Thailand’s Medical and Wellness Excellence

The Thai Pavilion at Expo 2025 will feature five key areas of excellence that set Thailand apart as a leader in healthcare:

1. Traditional Thai Healthcare: Emphasizing the harmony between humans and nature, traditional Thai medicine has been practiced for centuries and remains integral to the country’s identity.
2. Thai Herbs and Culinary Health: Thailand’s rich culinary traditions, such as the world-famous Tom Yum Goong, incorporate the healing power of Thai herbs, showcasing their health benefits.
3. Thai Herbal Medicine: Visitors will learn about unique herbal products such as aroma inhalers and therapeutic massage oils, commonly used to promote health and well-being.
4. Thai Massage: Recognized as a UNESCO cultural heritage, Thai massage is world-renowned for its healing properties, combining therapeutic techniques with relaxation.
5. Modern Medical Excellence: Thailand is a recognized leader in modern healthcare, with 62 medical organizations accredited by the Joint Commission International (JCI), ranking the country 4th globally and No. 1 in Southeast Asia.

A Thriving Medical Tourism Industry

Thailand’s healthcare services and exceptional hospitality have helped the country rank among the world’s top five medical tourism destinations. The industry is valued at one trillion baht and is expected to reach 2.2 trillion baht (64.02 billion USD) by 2034, contributing significantly to the country’s economic growth.

The Thai Experience at Expo 2025

“Thailand’s appeal as a medical and wellness hub is not only due to our advanced healthcare system but also our warm hospitality, rich cultural heritage, and stunning natural beauty,” Minister Somsak continued. “At Expo 2025, visitors will have the opportunity to experience these elements firsthand, and we hope to inspire them to explore more about Thai medicine and visit Thailand to discover these healing practices in person.”

A Global Gathering in Osaka

Expo 2025 will be held in Osaka, Japan, from April 13 to October 13, 2025, and is expected to attract 28 million visitors from around the world. Thailand’s participation will be a key opportunity to share its medical and wellness excellence on the global stage.

For more information, please contact
Thailand’s Ministry of Public Health
Email: thaipavilion.official@gmail.com
FACEBOOK: Thailandpavilionworldexpo2025

BEIJING, Jan. 22, 2025 /PRNewswire/ — Professor WANG Neng, Dean’s Distinguished Chair Professor of Finance and Senior Associate Dean at Cheung Kong Graduate School of Business (CKGSB), has been awarded the prestigious 2024 CBER-Circle Insight Award, an award jointly founded by the Crypto and Blockchain Economic Research (CBER) Forum and Circle, a prominent U.S. fintech company, which recognizes one groundbreaking academic study each year for its global impact. This honor highlights the world-class research expertise and significant global impact of CKGSB’s faculty.

Blockchain economics has become a pivotal area of exploration within economic research. The award-winning study, “Tokenomics: Dynamic Adoption and Valuation”, co-authored with Professor William Lin CONG from Cornell University’s SC Johnson College of Business and Professor Ye LI from the University of Washington, is one of the earliest theoretical frameworks in token pricing and a foundational study in the field. It has laid the groundwork for a wide range of theoretical and empirical studies, many of which have been featured in top-tier academic journals and presented at prominent conferences worldwide.

The study introduces a dynamic asset pricing model for blockchain platform tokens, illustrating how tokens drive user adoption and foster ecosystem growth. It also analyzes the nonlinear relationships between token prices and factors such as platform productivity, user heterogeneity, and network size. This research holds profound implications for understanding competition among blockchain platforms and the pricing of related assets.

As of January 2025, “Tokenomics: Dynamic Adoption and Valuation” had garnered over 730 citations on Google Scholar, ranking among the most-cited papers published in recent years by the Review of Financial Studies, one of the leading finance journals. Recognized as a top 1% highly cited paper in the Scopus database, the research has also informed policy decisions by major organizations, including the International Monetary Fund (IMF) and the Government of Canada.

About Cheung Kong Graduate School of Business (CKGSB)

Established in Beijing in November 2002, Cheung Kong Graduate School of Business (CKGSB) is China’s first privately-funded and research-driven business school. The school aims to cultivate transformative business leaders with a global vision, sense of social responsibility, innovative mindset, and ability to lead with empathy and compassion (https://english.ckgsb.edu.cn).

TAIPEI, Jan. 22, 2025 /PRNewswire/ — TPIsoftware has been commended with Best Employer Brand Awards by digital talent recruitment site Yourator in recognition of its commitment to Diversity, Equity and Inclusion (DEI) in the workplace. The award names 20 Taiwanese enterprises out of hundreds who excel in promoting fair treatment, equitable opportunities and workplace inclusiveness. TPIsoftware’s initiatives to foster gender equality, diversity and inclusion at work acknowledges its effective approaches to challenges of complex needs of talents, making it the most popular employer among candidates and employees.

The accolade follows the company’s last year recognition of 104 Best Employer Awards in the Employer of Choice by 104 Job Bank—Taiwan’s largest job search platform that connects millions of talents with employers across a broad range of industries. TPIsoftware’s unwavering focus on talent employment has earned recognition not only by prominent career platforms, but also the Taiwan Corporate Sustainability Award (TCSA) by the Taiwan Institute for Sustainable Energy—a prestigious award that validates a company’s effort to implement the Sustainable Development Goals.

Executive Vice President of TPIsoftware Mina Yieh said, “We commit ourselves to shaping an inclusive environment where everyone feels valued, respected and supported. Benefits and perks such as flexible working hours, remote working options, paid leave, mental health therapies and health check-ups are offered as we prioritize our employees’ well-being and development, both personally and professionally. We also support working parents by offering parental leave, childcare subsidies and accessibility to nursery rooms, showcasing our approaches to fulfilling parental responsibilities and family needs. At TPIsoftware, celebrating diversity and inclusion is not just a mantra or statement we make, it is reflected through well-rounded policies and programs.”

General Manager of TPIsoftware Yilan Yeh said, “Being a TCSA honoree reaffirms our endeavor in cultivating a gender-friendly, supportive workplace for all. A notable 3:2 male-to-female staff ratio is achieved, with a gender balance on managerial level. This makes TPIsoftware exceptional in the tech industry, where male dominance is the norm. Every member at our company can expect to reach their full potential and thrive regardless of their sociodemographic backgrounds. Not only do we invest in the workforce to lead in the digital world, but also inspire those around us to propel toward success and professional growth as we believe diverse talents fuel and sustain our journey of innovation and transformation.”

 TAIPEI, Jan. 22, 2025 /PRNewswire/ — TPIsoftware has been commended with Best Employer Brand Awards by digital talent recruitment site Yourator in recognition of its commitment to Diversity, Equity and Inclusion (DEI) in the workplace. The award names 20 Taiwanese enterprises out of hundreds who excel in promoting fair treatment, equitable opportunities and workplace inclusiveness. TPIsoftware’s initiatives to foster gender equality, diversity and inclusion at work acknowledges its effective approaches to challenges of complex needs of talents, making it the most popular employer among candidates and employees.

The accolade follows the company’s last year recognition of 104 Best Employer Awards in the Employer of Choice by 104 Job Bank—Taiwan’s largest job search platform that connects millions of talents with employers across a broad range of industries. TPIsoftware’s unwavering focus on talent employment has earned recognition not only by prominent career platforms, but also the Taiwan Corporate Sustainability Award (TCSA) by the Taiwan Institute for Sustainable Energy—a prestigious award that validates a company’s effort to implement the Sustainable Development Goals.

Executive Vice President of TPIsoftware Mina Yieh said, “We commit ourselves to shaping an inclusive environment where everyone feels valued, respected and supported. Benefits and perks such as flexible working hours, remote working options, paid leave, mental health therapies and health check-ups are offered as we prioritize our employees’ well-being and development, both personally and professionally. We also support working parents by offering parental leave, childcare subsidies and accessibility to nursery rooms, showcasing our approaches to fulfilling parental responsibilities and family needs. At TPIsoftware, celebrating diversity and inclusion is not just a mantra or statement we make, it is reflected through well-rounded policies and programs.”

General Manager of TPIsoftware Yilan Yeh said, “Being a TCSA honoree reaffirms our endeavor in cultivating a gender-friendly, supportive workplace for all. A notable 3:2 male-to-female staff ratio is achieved, with a gender balance on managerial level. This makes TPIsoftware exceptional in the tech industry, where male dominance is the norm. Every member at our company can expect to reach their full potential and thrive regardless of their sociodemographic backgrounds. Not only do we invest in the workforce to lead in the digital world, but also inspire those around us to propel toward success and professional growth as we believe diverse talents fuel and sustain our journey of innovation and transformation.”

Discover new destinations and partners in Tokyo with Tokyo Virtual Trip 2025!

TOKYO, Jan. 22, 2025 /PRNewswire/ — Tokyo Convention & Visitors Bureau is announcing a limited-time event in February 2025 hosted on its online business matching platform, Tokyo Tourism Connection ( https://tokyotourismconnection.jp ), as part of their efforts to promote business and attract inbound tourism. This event offers an excellent opportunity for international travel industry professionals to discover a new side of Tokyo, as a means to create more engaging tours that fully highlight the city’s unique charms.

Overview

Event name:  Virtual Tour of Tokyo 2025

1) Tokyo Islands Chill Out – Hachijojima Island
2) Tokyo New Basic
Organizer: Tokyo Convention & Visitors Bureau
Location:  https://tokyotourismconnection.jp

Format: Online
Objective: Participating travel industry professionals can explore the hidden gems and undiscovered wonders of Tokyo, contribute to the development of new Tokyo-bound travel packages, and gain ideas for strengthening new partnerships.
Target: Travel industry professionals
Language: English only
Participation: Free of charge (prior registration is required on the official website).
Register: https://tokyotourismconnection.jp

Event Details

1. Tokyo Islands Chill Out – Hachijojima Island

• Period: Monday, February 10, 2025 – Saturday, February 15, 2025
• Overview: Let’s explore the nature and culture of Hachijojima, an island in Tokyo known for its rich natural environment.

A perfect chill out and sustainable tourism experience, while enjoying trekking among the woods and savory local cuisine.
This event should give you an idea to plan your new itinerary to Tokyo.

2. Tokyo New Basic

• Period: Monday, February 17, 2025 – Saturday, February 22, 2025
• Overview: Discover a “New Tokyo”, where Tokyo’s tradition and innovation blend seamlessly.

Be the first to introduce Tokyo’s latest cultural experiences in Harajuku, Ginza, Asakusa and Shinjuku,which should satisfy both first-time and repeat visitors to Tokyo.

About Tokyo Tourism Connection
Tokyo Tourism Connection is an online platform that helps partner overseas companies interested in developing travel products with local businesses in Tokyo. The platform supports overseas companies in the planning of special experiences and trips through a network of Tokyo tourism providers. Additionally, it offers resources for global travel industry professionals to explore Tokyo’s culture, cuisine, and entertainment, helping them design memorable travel experiences for visitors.
Those who register receive continuous access to related events and materials, offering insights and resources to support the growth of tourism-related businesses in Tokyo.

Services Provided:

• Business Events and Seminars – Join Tokyo’s online seminars and access event video archives.
• Business Matching Support – Search and contact tourism business partners in Tokyo.
• Tokyo Tourist Information and Tips – Find Tokyo tourism information and links to various useful sites.

Website URL: https://tokyotourismconnection.jp